Gene: Plat (plasminogen activator, tissue type) Rattus norvegicus
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Symbol: Plat
Name: plasminogen activator, tissue type
Description: ENCODES a protein that exhibits phosphoprotein binding (ortholog); receptor binding (ortholog); serine-type endopeptidase activity (ortholog); INVOLVED IN cellular response to dexamethasone stimulus; cellular response to follicle-stimulating hormone stimulus; cellular response to luteinizing hormone stimulus; PARTICIPATES IN acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; aminocaproic acid pharmacodynamics pathway; ASSOCIATED WITH Acute Traumatic Coagulopathy; Brain Edema; brain edema; FOUND IN cytoplasm; extracellular space; synapse; INTERACTS WITH (+)-catechin; (R)-mevalonic acid; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: PATISS; plasminogen activator, tissue; t-PA; t-plasminogen activator; tissue plasminogen activator; tissue-type plasminogen activator; tPA
Orthologs:
Homo sapiens (human) : PLAT (plasminogen activator, tissue type)  HGNC
Mus musculus (house mouse) : Plat (plasminogen activator, tissue)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Plat (plasminogen activator, tissue type)
Pan paniscus (bonobo/pygmy chimpanzee) : PLAT (plasminogen activator, tissue type)
Canis lupus familiaris (dog) : PLAT (plasminogen activator, tissue type)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plat (plasminogen activator, tissue type)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01674,098,263 - 74,122,897 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01673,730,256 - 73,754,851 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41673,711,323 - 73,736,328 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11673,711,587 - 73,736,593 (-)NCBI
Celera1667,134,451 - 67,159,047 (-)NCBI
Cytogenetic Map16q12.5NCBImapview
RH 3.4 Map16644.8RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Plat
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 3342
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-05-30
Status: ACTIVE