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Gene-Chemical Interaction AnnotationsGene-Chemical Interaction Annotations
Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of RIMS1 mRNA | CTD | PMID:15834898 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of RIMS1 mRNA | CTD | PMID:16483693 | dichlorine | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in increased expression of RIMS1 mRNA | CTD | PMID:18636392 | haloperidol | decreases expression | EXP | | 6480464 | Haloperidol results in decreased expression of RIMS1 mRNA | CTD | PMID:15860345 | mono(2-ethylhexyl) phthalate | increases expression | ISO | RGD:1558300 | 6480464 | mono-(2-ethylhexyl)phthalate results in increased expression of RIMS1 mRNA | CTD | PMID:22401849 | ozone | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in increased expression of RIMS1 mRNA | CTD | PMID:18636392 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsMolecular Pathway Annotations| External Database Links | |
| KEGG Pathway | Retrograde endocannabinoid signaling |
| Synaptic vesicle cycle | |
| Pathway Interaction Database | Effects of Botulinum toxin (PID:200187) |
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Molecular Pathway Annotations| External Database Links | |
| KEGG Pathway | Retrograde endocannabinoid signaling |
| Synaptic vesicle cycle | |
| Pathway Interaction Database | Effects of Botulinum toxin (PID:200187) |
References - curated| 1. |
Coppola T, etal., J Biol Chem 2001 Aug 31;276(35):32756-62. |
| 2. |
NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 3. |
Ohtsuka T, etal., J Cell Biol 2002 Aug 5;158(3):577-90. Epub 2002 Aug 5. |
| 4. |
RGD automated import pipeline for gene-chemical interactions |
| 5. |
RGD Automated Pipelines |
| 6. |
Schoch S, etal., Nature 2002 Jan 17;415(6869):321-6. |
| 7. |
Wang Y, etal., J Biol Chem 2000 Jun 30;275(26):20033-44. |
| 8. |
Wang Y, etal., Nature 1997 Aug 7;388(6642):593-8. |
| 9. |
Yang Y and Calakos N, J Neurosci. 2011 Aug 17;31(33):12053-7. |
References - uncuratedRGD Disease PortalsComparative Map Data| Rims1 (Rattus norvegicus) |
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| RIMS1 (Homo sapiens) |
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| Rims1 (Mus musculus) |
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Position Markers| D9Wox34 |
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| BF386262 |
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| BE101604 |
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| BF400263 |
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| BF401631 |
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| BE113512 |
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| BF405023 |
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| AU048318 |
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| RH138351 |
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| BF390485 |
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| AI406393 |
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QTLs in Region (RGSC Genome Assembly v3.4)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
Nucleotide Sequences| Nucleotide RefSeqs | NM_052829 | (Get FASTA) | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AABR06059249 | (Get FASTA) | Search GEO for Microarray Profiles |
| AABR06059250 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059251 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059252 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059253 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059254 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059255 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059256 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059257 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059258 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059259 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059260 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059261 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059262 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059263 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059264 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059265 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059266 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059267 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059268 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059269 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059270 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059271 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059272 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059273 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059274 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059275 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06059276 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058746 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058747 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058748 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058749 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058750 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058751 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058752 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058753 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058754 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058755 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058756 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058757 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058758 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058759 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058760 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058761 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058762 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058763 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058764 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058765 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058766 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058767 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058768 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058769 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058770 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058771 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058772 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058773 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058774 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058775 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058776 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058777 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AF007836 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AF199333 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CH473987 | (Get FASTA) | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_052829 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Protein Acc Id: | NP_439894 | ||||||||||||||||||||
| Position: |
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Protein Sequences| Protein RefSeqs | NP_439894 | (Get FASTA) |
| GenBank Protein | AAB66703 | (Get FASTA) |
| AAF81655 | (Get FASTA) | |
| EDM18632 | (Get FASTA) | |
| Q9JIR4 | (Get FASTA) |
Strain Sequence Variants
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External Database Links| Database | Acc Id | Source(s) |
| BIND | 128229 | |
| 128230 | ||
| 130538 | ||
| 130594 | ||
| Ensembl Genes | ENSRNOG00000011000 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000015454 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000015453 | ENTREZGENE, UniProtKB/TrEMBL |
| Entrez Gene | 84556 | ENTREZGENE |
| Gene3D-CATH | Znf_RING/FYVE/PHD | UniProtKB/Swiss-Prot |
| HomoloGene Group ID | 128399 | ENTREZGENE |
| InterPro | C2_Ca-dep | UniProtKB/Swiss-Prot |
| C2_Ca/lipid-bd_dom_CaLB | UniProtKB/Swiss-Prot | |
| C2_membr_targeting | UniProtKB/Swiss-Prot | |
| PDZ/DHR/GLGF | UniProtKB/Swiss-Prot | |
| Rab_bd_domain | UniProtKB/Swiss-Prot | |
| Znf_FYVE-rel | UniProtKB/Swiss-Prot | |
| Znf_FYVE_PHD | UniProtKB/Swiss-Prot | |
| Znf_RING/FYVE/PHD | UniProtKB/Swiss-Prot | |
| IPI | IPI00200893 | UniProtKB/Swiss-Prot |
| IPI00206312 | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:84556 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Pfam | PDZ | UniProtKB/Swiss-Prot |
| PF00168 | UniProtKB/Swiss-Prot | |
| PROSITE | PDZ | UniProtKB/Swiss-Prot |
| PS50004 | UniProtKB/Swiss-Prot | |
| RABBD | UniProtKB/Swiss-Prot | |
| ZF_FYVE | UniProtKB/Swiss-Prot | |
| SMART | PDZ | UniProtKB/Swiss-Prot |
| SM00239 | UniProtKB/Swiss-Prot | |
| Superfamily-SCOP | C2_CaLB | UniProtKB/Swiss-Prot |
| FYVE_PHD_ZnF | UniProtKB/Swiss-Prot | |
| PDZ | UniProtKB/Swiss-Prot | |
| UniGene | Rn.10799 | ENTREZGENE |
| UniProt | F1LYS1_RAT | UniProtKB/TrEMBL |
| RIMS1_RAT | UniProtKB/Swiss-Prot |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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| 2005-11-17 | Rims1 | regulating synaptic membrane exocytosis 1 | Symbol updated | 10779 | APPROVED | ||
| 2004-09-10 | RIMS1 | regulating synaptic membrane exocytosis 1 | Rim1 | Rim1 protein | Symbol and Name updated | 10779 | APPROVED |
| 2002-08-07 | Rim1 | Rim1 protein | Symbol and Name status set to provisional | 1724 | PROVISIONAL |
| More on Rims1 | |
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Entrez Gene |
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Ensembl Gene |
| Genome Browser |
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NCBI Map Viewer |
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Vista |
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Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 620000 |
| Created: | 2002-08-06 |
| Species: | Rattus norvegicus |
| Last Modified: | 2013-04-16 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.
