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ONTOLOGY REPORT - ANNOTATIONS

Term:CD4-positive, alpha-beta T cell activation
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Accession:GO:0035710 term browser browse the term
Definition:The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.


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CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDH26 cadherin 26 involved_in IDA (PMID:28051089) UniProt PMID:28051089 NCBI chr20:59,958,423...60,035,934
Ensembl chr20:59,958,423...60,034,011 		JBrowse link
G NKG7 natural killer cell granule protein 7 involved_in ISS UniProt GO_REF:0000024 NCBI chr19:51,371,620...51,372,654
Ensembl chr19:51,371,606...51,372,701 		JBrowse link
G RSAD2 radical S-adenosyl methionine domain containing 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:6,865,885...6,898,239
Ensembl chr 2:6,865,557...6,898,239 		JBrowse link
G STOML2 stomatin like 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:35,099,776...35,103,195
Ensembl chr 9:35,099,776...35,103,195 		JBrowse link
activated CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFSF18 TNF superfamily member 18 NOT|involved_in ISO (MGI:5551556|PMID:24107315) UniProt PMID:24107315 MGI:5551556 NCBI chr 1:173,039,202...173,050,941
Ensembl chr 1:173,039,202...173,050,941 		JBrowse link
CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD81 CD81 molecule involved_in IDA (PMID:22307619) UniProt PMID:22307619 NCBI chr11:2,376,180...2,397,397
Ensembl chr11:2,376,177...2,397,802 		JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (MGI:4819294|PMID:20639485) BHF-UCL PMID:20639485 MGI:4819294 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,183,731...173,207,331 		JBrowse link
CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARMC5 armadillo repeat containing 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28169274) Ensembl
MGI		 PMID:28169274 GO_REF:0000107 NCBI chr16:31,458,304...31,467,167
Ensembl chr16:31,458,080...31,467,166 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23334952) Ensembl
MGI		 PMID:23334952 GO_REF:0000107 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929 		JBrowse link
G CD83 CD83 molecule involved_in
acts_upstream_of		 IEA
ISO		 (PMID:15322158) Ensembl
MGI		 PMID:15322158 GO_REF:0000107 NCBI chr 6:14,117,256...14,136,918
Ensembl chr 6:14,117,256...14,136,918 		JBrowse link
G FOXP3 forkhead box P3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17028180) Ensembl
MGI		 PMID:17028180 GO_REF:0000107 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G GIMAP1 GTPase, IMAP family member 1 acts_upstream_of_or_within ISO (PMID:20194894) MGI PMID:20194894 NCBI chr 7:150,716,613...150,724,284
Ensembl chr 7:150,716,606...150,724,284 		JBrowse link
G NKX2-3 NK2 homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10926756) Ensembl
MGI		 PMID:10926756 GO_REF:0000107 NCBI chr10:99,532,942...99,536,524
Ensembl chr10:99,532,942...99,536,524 		JBrowse link
G PAX1 paired box 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16093716) Ensembl
MGI		 PMID:16093716 GO_REF:0000107 NCBI chr20:21,705,664...21,718,481
Ensembl chr20:21,705,659...21,718,481 		JBrowse link
G RSAD2 radical S-adenosyl methionine domain containing 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:6,865,885...6,898,239
Ensembl chr 2:6,865,557...6,898,239 		JBrowse link
G SASH3 SAM and SH3 domain containing 3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16227612) Ensembl
MGI		 PMID:16227612 GO_REF:0000107 NCBI chr  X:129,779,949...129,795,201
Ensembl chr  X:129,779,949...129,795,201 		JBrowse link
G SATB1 SATB homeobox 1 acts_upstream_of_or_within ISO (PMID:10716941) MGI PMID:10716941 NCBI chr 3:18,345,377...18,445,592
Ensembl chr 3:18,345,377...18,445,621 		JBrowse link
CD4-positive, alpha-beta T cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTSL cathepsin L involved_in ISS UniProt GO_REF:0000024 NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469 		JBrowse link
G TOX thymocyte selection associated high mobility group box involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:58,805,412...59,119,147
Ensembl chr 8:58,805,412...59,119,147 		JBrowse link
CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARD11 caspase recruitment domain family member 11 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:12867038) Ensembl
MGI		 PMID:12867038 GO_REF:0000107 NCBI chr 7:2,906,142...3,043,867
Ensembl chr 7:2,906,142...3,044,228 		JBrowse link
G CBLB Cbl proto-oncogene B involved_in
acts_upstream_of		 IEA
ISO		 (PMID:14973438) Ensembl
MGI		 PMID:14973438 GO_REF:0000107 NCBI chr 3:105,655,461...105,869,449
Ensembl chr 3:105,655,461...105,869,552 		JBrowse link
G CD24 CD24 molecule acts_upstream_of ISO (PMID:15314074)
(PMID:8125140)		 MGI PMID:8125140 PMID:15314074 NCBI chr 6:106,969,831...106,976,855
Ensembl chr 6:106,969,831...106,975,627 		JBrowse link
G CD28 CD28 molecule involved_in
acts_upstream_of		 IEA
ISO		 (PMID:14973438), (PMID:8125140), (PMID:9368605)
(PMID:9368605)		 Ensembl
MGI		 PMID:8125140 PMID:9368605 PMID:14973438 GO_REF:0000107 NCBI chr 2:203,706,482...203,738,912
Ensembl chr 2:203,706,475...203,738,912 		JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex involved_in
acts_upstream_of		 IEA
ISO		 (PMID:11894097), (PMID:14973438), (PMID:8125140) Ensembl
MGI		 PMID:8125140 PMID:11894097 PMID:14973438 GO_REF:0000107 NCBI chr11:118,304,730...118,316,173
Ensembl chr11:118,304,730...118,316,175 		JBrowse link
G FOXP3 forkhead box P3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17028180) Ensembl
MGI		 PMID:17028180 GO_REF:0000107 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G ITCH itchy E3 ubiquitin protein ligase involved_in
acts_upstream_of		 IEA
ISO		 (PMID:14973438) Ensembl
MGI		 PMID:14973438 GO_REF:0000107 NCBI chr20:34,363,273...34,511,773
Ensembl chr20:34,363,235...34,511,773 		JBrowse link
G NDFIP1 Nedd4 family interacting protein 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17137798) Ensembl
MGI		 PMID:17137798 GO_REF:0000107 NCBI chr 5:142,108,779...142,154,440
Ensembl chr 5:142,108,779...142,154,440 		JBrowse link
G PRKCQ protein kinase C theta involved_in
acts_upstream_of		 IEA
ISO		 (PMID:12867038) Ensembl
MGI		 PMID:12867038 GO_REF:0000107 NCBI chr10:6,394,097...6,580,646
Ensembl chr10:6,427,143...6,580,301 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:11894098)
(PMID:11894097)		 Ensembl
MGI		 PMID:11894097 PMID:11894098 GO_REF:0000107 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G TNFRSF14 TNF receptor superfamily member 14 acts_upstream_of ISO (PMID:15568026) MGI PMID:15568026 NCBI chr 1:2,554,234...2,563,829
Ensembl chr 1:2,555,639...2,565,382 		JBrowse link
CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP3 forkhead box P3 involved_in
acts_upstream_of		 IMP
ISO
IEA		 (PMID:22079196)
(PMID:16301745), (PMID:18573908)
(PMID:16275384)		 CACAO
MGI
Ensembl		 PMID:16275384 PMID:16301745 PMID:18573908 PMID:22079196 GO_REF:0000107 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G FUT7 fucosyltransferase 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18573908) Ensembl
MGI		 PMID:18573908 GO_REF:0000107 NCBI chr 9:137,030,174...137,032,088
Ensembl chr 9:137,030,174...137,032,088 		JBrowse link
G IL2RG interleukin 2 receptor subunit gamma involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16227984) Ensembl
MGI		 PMID:16227984 GO_REF:0000107 NCBI chr  X:71,107,404...71,111,577
Ensembl chr  X:71,107,404...71,112,108 		JBrowse link
G NCOR1 nuclear receptor corepressor 1 acts_upstream_of_or_within ISO (PMID:11030619) MGI PMID:11030619 NCBI chr17:16,029,157...16,215,534
Ensembl chr17:16,029,065...16,218,185 		JBrowse link
G PLA2G2D phospholipase A2 group IID involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19564598) Ensembl
MGI		 PMID:19564598 GO_REF:0000107 NCBI chr 1:20,111,939...20,119,536
Ensembl chr 1:20,111,939...20,119,566 		JBrowse link
CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP3 forkhead box P3 involved_in TAS (PMID:18368049) UniProt PMID:18368049 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G TOX thymocyte selection associated high mobility group box involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:58,805,412...59,119,147
Ensembl chr 8:58,805,412...59,119,147 		JBrowse link
negative regulation of CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TARM1 T cell-interacting, activating receptor on myeloid cells 1 involved_in IDA (PMID:26311901) UniProt PMID:26311901 NCBI chr19:54,069,895...54,081,365
Ensembl chr19:54,069,895...54,081,365 		JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 involved_in IDA (PMID:17164348) BHF-UCL PMID:17164348 NCBI chr18:9,334,773...9,402,420
Ensembl chr18:9,334,767...9,402,420 		JBrowse link
negative regulation of CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD160 CD160 molecule involved_in IDA (PMID:18193050) UniProt PMID:18193050 NCBI chr 1:145,719,499...145,739,288
Ensembl chr 1:145,719,471...145,739,288 		JBrowse link
negative regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBFB core-binding factor subunit beta involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:67,029,149...67,101,058
Ensembl chr16:67,028,984...67,101,058 		JBrowse link
G HMGB1 high mobility group box 1 involved_in IDA (PMID:22473704) UniProt PMID:22473704 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G RUNX1 RUNX family transcription factor 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr21:34,787,801...35,049,302
Ensembl chr21:34,787,801...36,004,667 		JBrowse link
G RUNX3 RUNX family transcription factor 3 involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:24,899,511...24,965,138
Ensembl chr 1:24,899,511...24,965,121 		JBrowse link
negative regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARG2 arginase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708 		JBrowse link
G CBLB Cbl proto-oncogene B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14973438) Ensembl
MGI		 PMID:14973438 GO_REF:0000107 NCBI chr 3:105,655,461...105,869,449
Ensembl chr 3:105,655,461...105,869,552 		JBrowse link
G CD274 CD274 molecule involved_in IDA (PMID:24691993) UniProt PMID:24691993 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566 		JBrowse link
G CD44 CD44 molecule (IN blood group) involved_in ISO (MGI:5688819|PMID:25065622) UniProt PMID:25065622 MGI:5688819 NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402 		JBrowse link
G FOXP3 forkhead box P3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17028180) Ensembl
MGI		 PMID:17028180 GO_REF:0000107 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G ITCH itchy E3 ubiquitin protein ligase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14973438) Ensembl
MGI		 PMID:14973438 GO_REF:0000107 NCBI chr20:34,363,273...34,511,773
Ensembl chr20:34,363,235...34,511,773 		JBrowse link
G LGALS12 galectin 12 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:63,506,084...63,516,772
Ensembl chr11:63,506,052...63,516,774 		JBrowse link
G LGALS9 galectin 9 involved_in IDA
IEA
IBA		 (PMID:20209097) UniProt
TreeGrafter
GO_Central		 PMID:20209097 GO_REF:0000033 GO_REF:0000118 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
G LGALS9B galectin 9B involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr17:20,449,395...20,467,539
Ensembl chr17:20,449,395...20,467,539 		JBrowse link
G LGALS9C galectin 9C involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr17:18,476,789...18,494,945
Ensembl chr17:18,476,737...18,494,945 		JBrowse link
G LOC124907928 galectin-9C-like involved_in IEA TreeGrafter GO_REF:0000118
G NDFIP1 Nedd4 family interacting protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17137798) Ensembl
MGI		 PMID:17137798 GO_REF:0000107 NCBI chr 5:142,108,779...142,154,440
Ensembl chr 5:142,108,779...142,154,440 		JBrowse link
G TARM1 T cell-interacting, activating receptor on myeloid cells 1 involved_in ISO (MGI:5908526|PMID:26311901) UniProt PMID:26311901 MGI:5908526 NCBI chr19:54,069,895...54,081,365
Ensembl chr19:54,069,895...54,081,365 		JBrowse link
G TNFRSF14 TNF receptor superfamily member 14 acts_upstream_of_or_within ISO (PMID:15568026) MGI PMID:15568026 NCBI chr 1:2,554,234...2,563,829
Ensembl chr 1:2,555,639...2,565,382 		JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 involved_in IDA (PMID:17164348) BHF-UCL PMID:17164348 NCBI chr18:9,334,773...9,402,420
Ensembl chr18:9,334,767...9,402,420 		JBrowse link
G VSIR V-set immunoregulatory receptor involved_in
acts_upstream_of_or_within		 IMP
ISO		 (PMID:24691993)
(PMID:21383057)		 UniProt
MGI		 PMID:21383057 PMID:24691993 NCBI chr10:71,747,556...71,773,520
Ensembl chr10:71,747,556...71,773,520 		JBrowse link
G XCL1 X-C motif chemokine ligand 1 involved_in IDA (PMID:10887101) BHF-UCL PMID:10887101 NCBI chr 1:168,576,605...168,582,069
Ensembl chr 1:168,576,605...168,582,069 		JBrowse link
negative regulation of T-helper 1 cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G XCL1 X-C motif chemokine ligand 1 involved_in IDA (PMID:10887101) BHF-UCL PMID:10887101 NCBI chr 1:168,576,605...168,582,069
Ensembl chr 1:168,576,605...168,582,069 		JBrowse link
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL2 achaete-scute family bHLH transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:2,268,498...2,270,588
Ensembl chr11:2,268,498...2,270,588 		JBrowse link
G IL4R interleukin 4 receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16424184) Ensembl
MGI		 PMID:16424184 GO_REF:0000107 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G JAK3 Janus kinase 3 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr19:17,824,782...17,847,982
Ensembl chr19:17,824,780...17,848,071 		JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,183,731...173,207,331 		JBrowse link
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL2 achaete-scute family bHLH transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:2,268,498...2,270,588
Ensembl chr11:2,268,498...2,270,588 		JBrowse link
G FOXP3 forkhead box P3 involved_in IMP (PMID:23169781) UniProt PMID:23169781 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G IL2 interleukin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL4 interleukin 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18792410) TreeGrafter
MGI		 PMID:18792410 GO_REF:0000118 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G PF4 platelet factor 4 ISO RGD PMID:24986443 RGD:329901907 NCBI chr 4:73,980,811...73,982,124
Ensembl chr 4:73,980,811...73,982,027 		JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:173,931,084...174,022,357
Ensembl chr 1:173,931,084...174,022,357 		JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:122,844,556...122,905,359
Ensembl chr 9:122,844,556...122,905,359 		JBrowse link
G SMAD7 SMAD family member 7 involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr18:48,919,853...48,950,965
Ensembl chr18:48,919,853...48,950,965 		JBrowse link
G TBX21 T-box transcription factor 21 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122 		JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23034280) Ensembl
MGI		 PMID:23034280 GO_REF:0000107 NCBI chr 1:155,001,750...155,018,523
Ensembl chr 1:155,002,630...155,018,523 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:37,474,580...37,484,377
Ensembl chr 1:37,474,580...37,484,377 		JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOXL3 lysyl oxidase like 3 involved_in IEA
IDA
ISS		 (PMID:28065600) Ensembl
UniProt		 PMID:28065600 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:74,532,258...74,555,702
Ensembl chr 2:74,532,258...74,555,690 		JBrowse link
G TBX21 T-box transcription factor 21 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122 		JBrowse link
G TNFSF18 TNF superfamily member 18 involved_in ISO (MGI:5551556|PMID:24107315) UniProt PMID:24107315 MGI:5551556 NCBI chr 1:173,039,202...173,050,941
Ensembl chr 1:173,039,202...173,050,941 		JBrowse link
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 involved_in IDA
IEA		 (PMID:17008549) UniProt
TreeGrafter		 PMID:17008549 GO_REF:0000118 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393 		JBrowse link
G ASCL2 achaete-scute family bHLH transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:2,268,498...2,270,588
Ensembl chr11:2,268,498...2,270,588 		JBrowse link
G BCL6 BCL6 transcription repressor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12594267) Ensembl
MGI		 PMID:12594267 GO_REF:0000107 NCBI chr 3:187,721,377...187,745,468
Ensembl chr 3:187,721,377...187,745,725 		JBrowse link
G HLX H2.0 like homeobox involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16424184) Ensembl
MGI		 PMID:16424184 GO_REF:0000107 NCBI chr 1:220,879,443...220,885,059
Ensembl chr 1:220,879,431...220,885,059 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:46,698,937...46,763,129
Ensembl chr 2:46,698,952...46,780,245 		JBrowse link
G ZNF271P zinc finger protein 271, pseudogene acts_upstream_of_or_within ISO (PMID:19783676) MGI PMID:19783676 NCBI chr18:35,290,272...35,310,766
Ensembl chr18:35,290,276...35,328,390
Ensembl chr18:35,290,276...35,328,390 		JBrowse link
negative regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RC3H1 ring finger and CCCH-type domains 1 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:15917799) BHF-UCL
MGI
Ensembl		 PMID:15917799 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:173,931,084...174,022,357
Ensembl chr 1:173,931,084...174,022,357 		JBrowse link
positive regulation of CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD55 CD55 molecule (Cromer blood group) involved_in IDA (PMID:16818763) UniProt PMID:16818763 NCBI chr 1:207,321,678...207,360,966
Ensembl chr 1:207,321,519...207,386,804 		JBrowse link
G HLA-DRA major histocompatibility complex, class II, DR alpha involved_in IDA (PMID:15265931) UniProt PMID:15265931 NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 involved_in IDA (PMID:15265931) UniProt PMID:15265931 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G HLA-DRB3 major histocompatibility complex, class II, DR beta 3 involved_in IDA (PMID:19531622) UniProt PMID:19531622
positive regulation of CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFSF4 TNF superfamily member 4 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,183,731...173,207,331 		JBrowse link
positive regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD83 CD83 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15322158) Ensembl
MGI		 PMID:15322158 GO_REF:0000107 NCBI chr 6:14,117,256...14,136,918
Ensembl chr 6:14,117,256...14,136,918 		JBrowse link
G FOXP3 forkhead box P3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17028180) Ensembl
MGI		 PMID:17028180 GO_REF:0000107 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:54,497,752...54,548,243
Ensembl chr12:54,497,752...54,548,243 		JBrowse link
G SASH3 SAM and SH3 domain containing 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16227612) Ensembl
MGI		 PMID:16227612 GO_REF:0000107 NCBI chr  X:129,779,949...129,795,201
Ensembl chr  X:129,779,949...129,795,201 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:11,254,417...11,256,204
Ensembl chr16:11,254,417...11,256,204 		JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,183,731...173,207,331 		JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:155,001,750...155,018,523
Ensembl chr 1:155,002,630...155,018,523 		JBrowse link
positive regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARD11 caspase recruitment domain family member 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12867038) Ensembl
MGI		 PMID:12867038 GO_REF:0000107 NCBI chr 7:2,906,142...3,043,867
Ensembl chr 7:2,906,142...3,044,228 		JBrowse link
G CD24 CD24 molecule acts_upstream_of_or_within ISO (PMID:8125140)
(PMID:15314074)		 MGI PMID:8125140 PMID:15314074 NCBI chr 6:106,969,831...106,976,855
Ensembl chr 6:106,969,831...106,975,627 		JBrowse link
G CD28 CD28 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9368605)
(PMID:14973438), (PMID:8125140), (PMID:9368605)		 Ensembl
MGI		 PMID:8125140 PMID:9368605 PMID:14973438 GO_REF:0000107 NCBI chr 2:203,706,482...203,738,912
Ensembl chr 2:203,706,475...203,738,912 		JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894097), (PMID:14973438), (PMID:8125140) Ensembl
MGI		 PMID:8125140 PMID:11894097 PMID:14973438 GO_REF:0000107 NCBI chr11:118,304,730...118,316,173
Ensembl chr11:118,304,730...118,316,175 		JBrowse link
G CD55 CD55 molecule (Cromer blood group) involved_in IDA (PMID:16818763) UniProt PMID:16818763 NCBI chr 1:207,321,678...207,360,966
Ensembl chr 1:207,321,519...207,386,804 		JBrowse link
G CD81 CD81 molecule involved_in IDA (PMID:22307619) UniProt PMID:22307619 NCBI chr11:2,376,180...2,397,397
Ensembl chr11:2,376,177...2,397,802 		JBrowse link
G IRGM immunity related GTPase M involved_in ISO (MGI:3822251|PMID:18806793) UniProt PMID:18806793 MGI:3822251 NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,521...150,900,736 		JBrowse link
G LGALS9 galectin 9 involved_in IDA (PMID:16116184) UniProt PMID:16116184 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
G PRKCQ protein kinase C theta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12867038) Ensembl
MGI		 PMID:12867038 GO_REF:0000107 NCBI chr10:6,394,097...6,580,646
Ensembl chr10:6,427,143...6,580,301 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894098)
(PMID:11894097)		 Ensembl
MGI		 PMID:11894097 PMID:11894098 GO_REF:0000107 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 involved_in IDA (PMID:17164348) BHF-UCL PMID:17164348 NCBI chr 3:30,606,356...30,694,142
Ensembl chr 3:30,606,601...30,694,142 		JBrowse link
G XCL1 X-C motif chemokine ligand 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:168,576,605...168,582,069
Ensembl chr 1:168,576,605...168,582,069 		JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP3 forkhead box P3 involved_in
acts_upstream_of_or_within		 TAS
ISO
IEA		 (PMID:18368049)
(PMID:16275384)
(PMID:16301745), (PMID:18573908)
(PMID:12612578)		 UniProt
MGI
Ensembl		 PMID:12612578 PMID:16275384 PMID:16301745 PMID:18368049 PMID:18573908 GO_REF:0000107 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G GIMAP5 GTPase, IMAP family member 5 ISO RGD PMID:15778366 RGD:2303772 NCBI chr 7:150,737,418...150,743,646
Ensembl chr 7:150,722,253...150,750,033 		JBrowse link
G HLA-DRA major histocompatibility complex, class II, DR alpha involved_in IDA (PMID:28467828) UniProt PMID:28467828 NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 involved_in IDA (PMID:28467828) UniProt PMID:28467828 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G IL2RG interleukin 2 receptor subunit gamma involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16227984) Ensembl
MGI		 PMID:16227984 GO_REF:0000107 NCBI chr  X:71,107,404...71,111,577
Ensembl chr  X:71,107,404...71,112,108 		JBrowse link
G KLHL25 kelch like family member 25 involved_in IEA
IDA		 (PMID:34491895) Ensembl
UniProt		 PMID:34491895 GO_REF:0000107 NCBI chr15:85,759,326...85,794,925
Ensembl chr15:85,759,326...85,794,925 		JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma involved_in IDA (PMID:20209097) UniProt PMID:20209097 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G LGALS9 galectin 9 involved_in IDA (PMID:20209097) UniProt PMID:20209097 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 involved_in IDA
IEA		 (PMID:17008549) UniProt
TreeGrafter		 PMID:17008549 GO_REF:0000118 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393 		JBrowse link
G CCL19 C-C motif chemokine ligand 19 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 9:34,689,570...34,691,276
Ensembl chr 9:34,689,570...34,691,276 		JBrowse link
G CD80 CD80 molecule involved_in NAS (PMID:9915850) UniProt PMID:9915850 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614 		JBrowse link
G HLX H2.0 like homeobox involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16424184) Ensembl
MGI		 PMID:16424184 GO_REF:0000107 NCBI chr 1:220,879,443...220,885,059
Ensembl chr 1:220,879,431...220,885,059 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894097) Ensembl
MGI		 PMID:11894097 GO_REF:0000107 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:46,698,937...46,763,129
Ensembl chr 2:46,698,952...46,780,245 		JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MALT1 MALT1 paracaspase involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr18:58,671,465...58,754,477
Ensembl chr18:58,671,465...58,754,477 		JBrowse link
G MIR21 microRNA 21 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MIR326 microRNA 326 acts_upstream_of_or_within ISO (PMID:19838199) MGI PMID:19838199 NCBI chr11:75,335,092...75,335,186
Ensembl chr11:75,335,092...75,335,186 		JBrowse link
G NFKBID NFKB inhibitor delta involved_in ISS UniProt GO_REF:0000024 NCBI chr19:35,887,952...35,902,303
Ensembl chr19:35,887,653...35,902,303 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:101,827,990...101,861,022
Ensembl chr 3:101,827,991...101,861,022 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108 		JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRD2 bromodomain containing 2 involved_in IEA
IDA		 (PMID:28262505) Ensembl
UniProt		 PMID:28262505 GO_REF:0000107 NCBI chr 6:32,968,594...32,981,505
Ensembl chr 6:32,968,594...32,981,505 		JBrowse link
G BRD4 bromodomain containing 4 involved_in ISS UniProt GO_REF:0000024 NCBI chr19:15,235,519...15,332,539
Ensembl chr19:15,235,519...15,332,545 		JBrowse link
G EP300 E1A binding protein p300 involved_in IDA (PMID:28262505) UniProt PMID:28262505 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077 		JBrowse link
G IL12B interleukin 12B involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL12RB1 interleukin 12 receptor subunit beta 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr19:18,058,995...18,098,816
Ensembl chr19:18,058,995...18,098,944 		JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IEA
IBA
ISS		 Ensembl
GO_Central
BHF-UCL		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410 		JBrowse link
G IL23R interleukin 23 receptor involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:67,138,637...67,265,903
Ensembl chr 1:67,138,907...67,259,979 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase involved_in ISS UniProt GO_REF:0000024 NCBI chr 3:193,593,208...193,697,811
Ensembl chr 3:193,593,144...193,697,811 		JBrowse link
positive regulation of T-helper 2 cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKCQ protein kinase C theta involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:6,394,097...6,580,646
Ensembl chr10:6,427,143...6,580,301 		JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (MGI:3763508|PMID:12496423) BHF-UCL PMID:12496423 MGI:3763508 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,183,731...173,207,331 		JBrowse link
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD86 CD86 molecule involved_in NAS (PMID:9915850) UniProt PMID:9915850 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G IL18 interleukin 18 involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL4R interleukin 4 receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16424184) Ensembl
MGI		 PMID:16424184 GO_REF:0000107 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G IL6 interleukin 6 acts_upstream_of_or_within ISO (PMID:12594267) MGI PMID:12594267 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108 		JBrowse link
G PRKCZ protein kinase C zeta involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:2,048,504...2,185,395
Ensembl chr 1:2,050,411...2,185,395 		JBrowse link
G RARA retinoic acid receptor alpha involved_in IDA (PMID:18416830) BHF-UCL PMID:18416830 NCBI chr17:40,309,180...40,357,643
Ensembl chr17:40,309,180...40,357,643 		JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,183,731...173,207,331 		JBrowse link
positive regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SHB SH2 domain containing adaptor protein B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24645804) Ensembl
MGI		 PMID:24645804 GO_REF:0000107 NCBI chr 9:37,915,898...38,069,227
Ensembl chr 9:37,915,898...38,069,227 		JBrowse link
regulation of CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor involved_in IDA (PMID:22473704) UniProt PMID:22473704 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SH3RF1 SH3 domain containing ring finger 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 4:169,094,259...169,270,956
Ensembl chr 4:169,094,259...169,270,956 		JBrowse link
regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL2 interleukin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16227984) Ensembl
MGI		 PMID:16227984 GO_REF:0000107 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL2RA interleukin 2 receptor subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16227984) Ensembl
MGI		 PMID:16227984 GO_REF:0000107 NCBI chr10:6,010,689...6,062,367
Ensembl chr10:6,010,689...6,062,370 		JBrowse link
regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL27 interleukin 27 involved_in IDA
IBA		 (PMID:12734330) UniProt
GO_Central		 PMID:12734330 GO_REF:0000033 NCBI chr16:28,499,362...28,506,834
Ensembl chr16:28,499,362...28,512,051 		JBrowse link
regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor involved_in NAS (PMID:29234109) ComplexPortal PMID:29234109 NCBI chr14:75,522,469...75,546,992
Ensembl chr14:75,522,455...75,546,993 		JBrowse link
G CCL20 C-C motif chemokine ligand 20 NOT|involved_in ISO (MGI:3820359|PMID:19050256) UniProt PMID:19050256 MGI:3820359 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564 		JBrowse link
G CCR6 C-C motif chemokine receptor 6 NOT|involved_in ISO (MGI:3820359|PMID:19050256) UniProt PMID:19050256 MGI:3820359 NCBI chr 6:167,111,795...167,139,141
Ensembl chr 6:167,111,807...167,139,141 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit involved_in NAS (PMID:29234109) ComplexPortal PMID:29234109 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315 		JBrowse link
G MIR301A microRNA 301a acts_upstream_of_or_within ISO (PMID:22517757) MGI PMID:22517757 NCBI chr17:59,151,136...59,151,221
Ensembl chr17:59,151,136...59,151,221 		JBrowse link
regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA3 GATA binding protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18776904) Ensembl
MGI		 PMID:18776904 GO_REF:0000107 NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,378...8,075,198 		JBrowse link
G HLA-DRA major histocompatibility complex, class II, DR alpha involved_in IDA (PMID:15322540) UniProt PMID:15322540 NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 involved_in IDA (PMID:15322540) UniProt PMID:15322540 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G IRF4 interferon regulatory factor 4 involved_in NAS (PMID:12374808) UniProt PMID:12374808 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443 		JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18776904) Ensembl
MGI		 PMID:18776904 GO_REF:0000107 NCBI chr 1:155,001,750...155,018,523
Ensembl chr 1:155,002,630...155,018,523 		JBrowse link
T follicular helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL2 achaete-scute family bHLH transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:2,268,498...2,270,588
Ensembl chr11:2,268,498...2,270,588 		JBrowse link
G FOXP1 forkhead box P1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 3:70,954,708...71,583,978
Ensembl chr 3:70,954,693...71,583,978 		JBrowse link
G GPR183 G protein-coupled receptor 183 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr13:99,294,539...99,307,399
Ensembl chr13:99,294,539...99,307,399 		JBrowse link
G IL21 interleukin 21 involved_in ISS UniProt GO_REF:0000024 NCBI chr 4:122,610,108...122,621,066
Ensembl chr 4:122,610,108...122,621,066 		JBrowse link
G IL6 interleukin 6 involved_in ISS UniProt GO_REF:0000024 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23583643) Ensembl
MGI		 PMID:23583643 GO_REF:0000107 NCBI chr 1:173,931,084...174,022,357
Ensembl chr 1:173,931,084...174,022,357 		JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23583643) Ensembl
MGI		 PMID:23583643 GO_REF:0000107 NCBI chr 9:122,844,556...122,905,359
Ensembl chr 9:122,844,556...122,905,359 		JBrowse link
T-helper 1 cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEBPB CCAAT enhancer binding protein beta involved_in ISS UniProt GO_REF:0000024 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668 		JBrowse link
G HMGB1 high mobility group box 1 involved_in IDA (PMID:22473704) UniProt PMID:22473704 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G IL12A interleukin 12A acts_upstream_of_or_within ISO (PMID:22851706) MGI PMID:22851706 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019 		JBrowse link
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15284856) Ensembl
MGI		 PMID:15284856 GO_REF:0000107 NCBI chr11:68,039,025...68,053,762
Ensembl chr11:68,039,025...68,050,895 		JBrowse link
T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRACR2A calcium release activated channel regulator 2A involved_in IMP (PMID:29987160) UniProt PMID:29987160 NCBI chr12:3,615,328...3,753,109
Ensembl chr12:3,606,633...3,764,819 		JBrowse link
G HLX H2.0 like homeobox involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16424184) Ensembl
MGI		 PMID:16424184 GO_REF:0000107 NCBI chr 1:220,879,443...220,885,059
Ensembl chr 1:220,879,431...220,885,059 		JBrowse link
G HMGB1 high mobility group box 1 involved_in IMP (PMID:15944249) UniProt PMID:15944249 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G IL18R1 interleukin 18 receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10227969) Ensembl
MGI		 PMID:10227969 GO_REF:0000107 NCBI chr 2:102,355,796...102,398,776
Ensembl chr 2:102,311,529...102,398,777 		JBrowse link
G IL4R interleukin 4 receptor involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16424184) Ensembl
MGI		 PMID:16424184 GO_REF:0000107 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G LEF1 lymphoid enhancer binding factor 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:108,047,548...108,168,932
Ensembl chr 4:108,047,545...108,168,956 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:101,827,990...101,861,022
Ensembl chr 3:101,827,991...101,861,022 		JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16081776) Ensembl
MGI		 PMID:16081776 GO_REF:0000107 NCBI chr19:45,001,464...45,038,192
Ensembl chr19:45,001,461...45,038,192 		JBrowse link
G SEMA4A semaphorin 4A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:156,147,373...156,177,744
Ensembl chr 1:156,147,366...156,177,752 		JBrowse link
G STAT4 signal transducer and activator of transcription 4 involved_in IDA (PMID:14688310) UniProt PMID:14688310 NCBI chr 2:191,029,576...191,151,596
Ensembl chr 2:191,029,576...191,151,596 		JBrowse link
G TMEM98 transmembrane protein 98 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:32,928,153...32,944,315
Ensembl chr17:32,927,910...32,945,106 		JBrowse link
T-helper 1 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL4 interleukin 4 acts_upstream_of_or_within ISO (PMID:20706986) MGI PMID:20706986 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G SPN sialophorin involved_in IDA (PMID:18036228) UniProt PMID:18036228 NCBI chr16:29,662,963...29,670,876
Ensembl chr16:29,662,979...29,670,876 		JBrowse link
G STAT6 signal transducer and activator of transcription 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20706986) Ensembl
MGI		 PMID:20706986 GO_REF:0000107 NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139 		JBrowse link
G TBX21 T-box transcription factor 21 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122 		JBrowse link
T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:75,522,469...75,546,992
Ensembl chr14:75,522,455...75,546,993 		JBrowse link
G ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:99,659,509...99,711,241
Ensembl chr10:99,659,509...99,711,241 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:101,827,990...101,861,022
Ensembl chr 3:101,827,991...101,861,022 		JBrowse link
G RORA RAR related orphan receptor A involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:60,488,284...61,229,302
Ensembl chr15:60,488,284...61,229,302 		JBrowse link
G RORC RAR related orphan receptor C involved_in
acts_upstream_of_or_within		 ISS
ISO		 (PMID:18792410) UniProt
MGI		 PMID:18792410 GO_REF:0000024 NCBI chr 1:151,806,071...151,831,802
Ensembl chr 1:151,806,071...151,831,845 		JBrowse link
T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:75,522,469...75,546,992
Ensembl chr14:75,522,455...75,546,993 		JBrowse link
G IL6 interleukin 6 involved_in ISS (PMID:27893700) UniProt PMID:27893700 GO_REF:0000024 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL6R interleukin 6 receptor involved_in IEA
ISS		 (PMID:27893700) Ensembl
UniProt		 PMID:27893700 GO_REF:0000107 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450 		JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer involved_in ISS (PMID:27893700) UniProt PMID:27893700 NCBI chr 5:55,935,095...55,994,963
Ensembl chr 5:55,935,095...55,995,022 		JBrowse link
G IRF4 interferon regulatory factor 4 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443 		JBrowse link
G JAK1 Janus kinase 1 involved_in TAS (PMID:27893700) UniProt PMID:27893700 NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,223...65,067,754 		JBrowse link
G LY9 lymphocyte antigen 9 involved_in IDA (PMID:22184727) UniProt PMID:22184727 NCBI chr 1:160,796,174...160,828,255
Ensembl chr 1:160,796,074...160,828,261 		JBrowse link
G OTUD5 OTU deubiquitinase 5 acts_upstream_of_or_within ISO (PMID:25470037) MGI PMID:25470037 NCBI chr  X:48,922,024...48,958,381
Ensembl chr  X:48,922,024...48,958,386 		JBrowse link
G SLAMF6 SLAM family member 6 involved_in IDA
IBA
IEA		 (PMID:22184727) UniProt
GO_Central
TreeGrafter		 PMID:22184727 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:160,485,036...160,523,255
Ensembl chr 1:160,485,030...160,523,262 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 involved_in TAS (PMID:27893700) UniProt PMID:27893700 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
T-helper 2 cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFSF4 TNF superfamily member 4 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,183,731...173,207,331 		JBrowse link
T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:75,522,469...75,546,992
Ensembl chr14:75,522,455...75,546,993 		JBrowse link
G BCL3 BCL3 transcription coactivator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16081776) Ensembl
MGI		 PMID:16081776 GO_REF:0000107 NCBI chr19:44,747,705...44,760,044
Ensembl chr19:44,747,705...44,760,044 		JBrowse link
G BCL6 BCL6 transcription repressor involved_in
acts_upstream_of		 IEA
ISO		 (PMID:12594267) Ensembl
MGI		 PMID:12594267 GO_REF:0000107 NCBI chr 3:187,721,377...187,745,468
Ensembl chr 3:187,721,377...187,745,725 		JBrowse link
G GATA3 GATA binding protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO
IDA		 (PMID:20706986)
(PMID:20484083)		 Ensembl
MGI
UniProt		 PMID:20484083 PMID:20706986 GO_REF:0000107 NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,378...8,075,198 		JBrowse link
G HLX H2.0 like homeobox involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16424184) Ensembl
MGI		 PMID:16424184 GO_REF:0000107 NCBI chr 1:220,879,443...220,885,059
Ensembl chr 1:220,879,431...220,885,059 		JBrowse link
G IL4 interleukin 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20706986) TreeGrafter
MGI		 PMID:20706986 GO_REF:0000118 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL4R interleukin 4 receptor involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16424184) Ensembl
MGI		 PMID:16424184 GO_REF:0000107 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G IL6 interleukin 6 acts_upstream_of ISO (PMID:12594267) MGI PMID:12594267 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G KMT2A lysine methyltransferase 2A involved_in IDA (PMID:20484083) UniProt PMID:20484083 NCBI chr11:118,436,492...118,526,832
Ensembl chr11:118,436,456...118,526,832 		JBrowse link
G MEN1 menin 1 involved_in IDA (PMID:20484083) UniProt PMID:20484083 NCBI chr11:64,803,516...64,811,294
Ensembl chr11:64,803,510...64,811,294 		JBrowse link
G MYB MYB proto-oncogene, transcription factor involved_in IMP (PMID:20484083) UniProt PMID:20484083 NCBI chr 6:135,181,308...135,219,172
Ensembl chr 6:135,181,308...135,219,173 		JBrowse link
T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha involved_in
acts_upstream_of_or_within		 ISS
ISO		 (PMID:8434133) UniProt
MGI		 PMID:8434133 GO_REF:0000024 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,690...78,050,395 		JBrowse link
G IL12B interleukin 12B involved_in IDA (PMID:1673147) UniProt PMID:1673147 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G PDP2 pyruvate dehydrogenase phosphatase catalytic subunit 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:66,880,515...66,891,101
Ensembl chr16:66,878,589...66,895,754 		JBrowse link
G PTGER4 prostaglandin E receptor 4 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:40,679,915...40,746,800
Ensembl chr 5:40,679,915...40,693,735 		JBrowse link
G RORC RAR related orphan receptor C involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:151,806,071...151,831,802
Ensembl chr 1:151,806,071...151,831,845 		JBrowse link
T-helper cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZFPM1 zinc finger protein, FOG family member 1 involved_in IC (PMID:21646796) BHF-UCL PMID:21646796 NCBI chr16:88,451,769...88,537,031
Ensembl chr16:88,453,280...88,537,031 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19670
    immune system process 3226
      leukocyte activation 1138
        lymphocyte activation 932
          T cell activation 667
            alpha-beta T cell activation 222
              CD4-positive, alpha-beta T cell activation 146
                CD4-positive, alpha-beta T cell differentiation + 112
                CD4-positive, alpha-beta T cell proliferation + 30
                T-helper 1 cell activation + 5
                T-helper 2 cell activation + 2
                negative regulation of CD4-positive, alpha-beta T cell activation + 41
                positive regulation of CD4-positive, alpha-beta T cell activation + 53
                regulation of CD4-positive, alpha-beta T cell activation + 96
Path 2
Term Annotations click to browse term
  biological_process 19670
    cellular process 18301
      cell activation 1311
        leukocyte activation 1138
          lymphocyte activation 932
            T cell activation 667
              alpha-beta T cell activation 222
                CD4-positive, alpha-beta T cell activation 146
                  CD4-positive, alpha-beta T cell differentiation + 112
                  CD4-positive, alpha-beta T cell proliferation + 30
                  T-helper 1 cell activation + 5
                  T-helper 2 cell activation + 2
                  negative regulation of CD4-positive, alpha-beta T cell activation + 41
                  positive regulation of CD4-positive, alpha-beta T cell activation + 53
                  regulation of CD4-positive, alpha-beta T cell activation + 96
paths to the root