MEN1 (menin 1) - Rat Genome Database

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Gene: MEN1 (menin 1) Homo sapiens
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Symbol: MEN1
Name: menin 1
RGD ID: 736443
HGNC Page HGNC:7010
Description: Enables several functions, including DNA binding activity; R-SMAD binding activity; and protein N-terminus binding activity. Involved in several processes, including negative regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of nucleobase-containing compound metabolic process; and regulation of signal transduction. Acts upstream of or within negative regulation of osteoblast differentiation and osteoblast development. Located in several cellular components, including cleavage furrow; nuclear lumen; and transcription repressor complex. Part of histone methyltransferase complex. Implicated in endocrine gland cancer (multiple); hyperparathyroidism; and multiple endocrine neoplasia type 1. Biomarker of pancreatic ductal carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: endocrine adenomatosis, multiple; MEAI; menin; multiple endocrine neoplasia 1; multiple endocrine neoplasia I; SCG2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381164,803,516 - 64,811,294 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1164,803,510 - 64,811,294 (-)EnsemblGRCh38hg38GRCh38
GRCh371164,570,988 - 64,578,766 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361164,327,564 - 64,335,342 (-)NCBINCBI36hg18NCBI36
Build 341164,327,571 - 64,335,342NCBI
Celera1161,897,163 - 61,904,940 (-)NCBI
Cytogenetic Map11q13.1NCBI
HuRef1160,898,267 - 60,932,150 (-)NCBIHuRef
CHM1_11164,454,762 - 64,462,538 (-)NCBICHM1_1
T2T-CHM13v2.01164,796,826 - 64,804,601 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model