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Gene: TBX21 (T-box transcription factor 21) Homo sapiens
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Symbol: TBX21
Name: T-box transcription factor 21
Description: Exhibits sequence-specific DNA binding activity and transcription regulatory region DNA binding activity. Involved in lymphocyte migration; regulation of transcription, DNA-templated; and response to virus. Predicted to localize to the nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: T-bet; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; TBET; TBLYM; transcription factor TBLYM
Orthologs:
Mus musculus (house mouse) : Tbx21 (T-box 21)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tbx21 (T-box transcription factor 21)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbx21 (T-box transcription factor 21)
Pan paniscus (bonobo/pygmy chimpanzee) : TBX21 (T-box transcription factor 21)
Canis lupus familiaris (dog) : TBX21 (T-box transcription factor 21)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbx21 (T-box transcription factor 21)
Sus scrofa (pig) : TBX21 (T-box transcription factor 21)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381747,733,236 - 47,746,122 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371745,810,610 - 45,823,485 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361743,165,609 - 43,178,484 (+)NCBINCBI36hg18NCBI36
Build 341743,165,608 - 43,178,484NCBI
Celera1742,263,420 - 42,276,290 (+)NCBI
Cytogenetic Map17q21.32NCBI
HuRef1741,179,683 - 41,192,556 (+)NCBIHuRef
CHM1_11745,875,536 - 45,888,411 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TBX21
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317938
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.