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Gene: OTUD5 (OTU deubiquitinase 5) Homo sapiens
Symbol: OTUD5
Name: OTU deubiquitinase 5
Description: Exhibits Lys48-specific deubiquitinase activity; Lys63-specific deubiquitinase activity; and thiol-dependent ubiquitin-specific protease activity. Involved in protein K48-linked deubiquitination; protein K63-linked deubiquitination; and response to lipopolysaccharide. Predicted to localize to the cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: deubiquinating enzyme A; deubiquitinating enzyme A; DKFZp761A052; DUBA; MGC104871; OTU domain containing 5; OTU domain-containing protein 5
Mus musculus (house mouse) : Otud5 (OTU domain containing 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Otud5 (OTU deubiquitinase 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Otud5 (OTU deubiquitinase 5)
Pan paniscus (bonobo/pygmy chimpanzee) : OTUD5 (OTU deubiquitinase 5)
Canis lupus familiaris (dog) : OTUD5 (OTU deubiquitinase 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Otud5 (OTU deubiquitinase 5)
Sus scrofa (pig) : OTUD5 (OTU deubiquitinase 5)
Chlorocebus sabaeus (African green monkey) : OTUD5 (OTU deubiquitinase 5)
Heterocephalus glaber (naked mole-rat) : Otud5 (OTU deubiquitinase 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX48,922,028 - 48,958,386 (-)Ensembl
GRCh38X48,922,024 - 48,960,783 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X48,779,301 - 48,815,880 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,664,432 - 48,699,837 (-)NCBINCBI36hg18NCBI36
CeleraX52,847,869 - 52,884,227 (+)NCBI
Cytogenetic MapXp11.23NCBI
HuRefX46,435,456 - 46,472,247 (-)NCBIHuRef
CHM1_1X48,810,457 - 48,846,938 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on OTUD5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1604609
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.