CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: dibromobenzene
Accession: CHEBI:37147
browse the term
Definition: Any member of the class of bromobenzenes that consists of a benzene or a substituted benzene ring carrying two bromo groups at unspecified positions.
Synonyms: related_synonym: Formula=C6H4Br2; dibromobenzenes
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Cat
catalase
decreases activity
EXP
1,4-dibromobenzene results in decreased activity of CAT protein
CTD
PMID:16411567
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Casp3
caspase 3
increases expression multiple interactions
ISO
2,4-dibromophenol metabolite results in increased expression of CASP3 protein modified form Acetylcysteine inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of CASP3 protein modified form]; pifithrin promotes the reaction [2,4-dibromophenol metabolite results in increased expression of CASP3 protein modified form]; TRP53 inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of CASP3 protein modified form]
CTD
PMID:33961949
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
multiple interactions increases expression
ISO
Acetylcysteine inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of CDKN1A protein]; pifithrin inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of CDKN1A protein]; TRP53 promotes the reaction [2,4-dibromophenol metabolite results in increased expression of CDKN1A protein]
CTD
PMID:33961949
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cyp11a1
cytochrome P450, family 11, subfamily a, polypeptide 1
increases expression
ISO
2,4-dibromophenol results in increased expression of CYP11A1 mRNA
CTD
PMID:17447562
NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
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Cyp11b3
cytochrome P450, family 11, subfamily b, polypeptide 3
increases expression
ISO
2,4-dibromophenol results in increased expression of CYP11B2 mRNA
CTD
PMID:17447562
NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
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Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
increases expression
ISO
2,4-dibromophenol results in increased expression of CYP17A1 mRNA
CTD
PMID:17447562
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
increases expression
ISO
2,4-dibromophenol results in increased expression of CYP19A1 mRNA
CTD
PMID:17447562
NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
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H2ax
H2A.X variant histone
multiple interactions increases expression
ISO
Acetylcysteine inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of H2AX protein modified form]; pifithrin promotes the reaction [2,4-dibromophenol metabolite results in increased expression of H2AX protein modified form]; TRP53 inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of H2AX protein modified form]
CTD
PMID:33961949
NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
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Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
increases expression
ISO
2,4-dibromophenol results in increased expression of HMGCR mRNA
CTD
PMID:17447562
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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Hsd17b1
hydroxysteroid (17-beta) dehydrogenase 1
increases expression
ISO
2,4-dibromophenol results in increased expression of HSD17B1 mRNA
CTD
PMID:17447562
NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
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Hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
increases expression
ISO
2,4-dibromophenol results in increased expression of HSD17B4 mRNA
CTD
PMID:17447562
NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
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Hsd3b2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
increases expression
ISO
2,4-dibromophenol results in increased expression of HSD3B2 mRNA
CTD
PMID:17447562
NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852
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Star
steroidogenic acute regulatory protein
increases expression
ISO
2,4-dibromophenol results in increased expression of STAR mRNA
CTD
PMID:17447562
NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
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Tp53
tumor protein p53
multiple interactions increases expression
ISO
2,4-dibromophenol metabolite results in increased expression of and affects the localization of TRP53 protein; Acetylcysteine inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of TRP53 protein modified form]; Acetylcysteine inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of TRP53 protein]; TRP53 inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of CASP3 protein modified form]; TRP53 inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of H2AX protein modified form]; TRP53 promotes the reaction [2,4-dibromophenol metabolite results in increased expression of CDKN1A protein]
CTD
PMID:33961949
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Ttr
transthyretin
affects binding
ISO
2,4-dibromophenol binds to TTR protein
CTD
PMID:10869457
NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
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Cyp11b3
cytochrome P450, family 11, subfamily b, polypeptide 3
decreases expression
ISO
2,6-dibromophenol results in decreased expression of CYP11B2 mRNA
CTD
PMID:17447562
NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
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Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
decreases expression
ISO
2,6-dibromophenol results in decreased expression of CYP17A1 mRNA
CTD
PMID:17447562
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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Hsd17b1
hydroxysteroid (17-beta) dehydrogenase 1
decreases expression
ISO
2,6-dibromophenol results in decreased expression of HSD17B1 mRNA
CTD
PMID:17447562
NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
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Hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
decreases expression
ISO
2,6-dibromophenol results in decreased expression of HSD17B4 mRNA
CTD
PMID:17447562
NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
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Hsd3b2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
increases expression
ISO
2,6-dibromophenol results in increased expression of HSD3B2 mRNA
CTD
PMID:17447562
NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852
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Star
steroidogenic acute regulatory protein
decreases expression
ISO
2,6-dibromophenol results in decreased expression of STAR mRNA
CTD
PMID:17447562
NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
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Gja1
gap junction protein, alpha 1
decreases activity
EXP
bromoxynil results in decreased activity of GJA1 protein
CTD
PMID:20510257
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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Ttr
transthyretin
affects binding
EXP
bromoxynil binds to TTR protein
CTD
PMID:2043046
NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
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Abcb11
ATP binding cassette subfamily B member 11
decreases activity multiple interactions
ISO
Benzbromarone results in decreased activity of ABCB11 protein Benzbromarone inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
CTD
PMID:20829430 PMID:23956101 PMID:24014644 PMID:28437613
NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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Abcb1a
ATP binding cassette subfamily B member 1A
affects expression
EXP
Benzbromarone affects the expression of ABCB1A mRNA
CTD
PMID:19483382
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Abcb4
ATP binding cassette subfamily B member 4
decreases activity
ISO
Benzbromarone results in decreased activity of ABCB4 protein
CTD
PMID:28437613
NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
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Abcc1
ATP binding cassette subfamily C member 1
multiple interactions affects activity
ISO
Benzbromarone inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]; Benzbromarone inhibits the reaction [ABCC1 protein results in increased secretion of Daunorubicin] Benzbromarone affects the activity of ABCC1 protein
CTD
PMID:9096673 PMID:9334814 PMID:15041471 PMID:16101123
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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Abcc2
ATP binding cassette subfamily C member 2
multiple interactions decreases activity
EXP ISO
[Benzbromarone results in decreased activity of ABCC2 protein] inhibits the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]; [Benzbromarone results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium Benzbromarone inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]
CTD
PMID:19782883 PMID:19853032 PMID:22646477 PMID:31348918
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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Abcc3
ATP binding cassette subfamily C member 3
multiple interactions
ISO
Benzbromarone inhibits the reaction [ABCC3 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; yu ping feng san inhibits the reaction [Benzbromarone results in increased activity of ABCC3 protein]
CTD
PMID:31348918 PMID:34135758
NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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Abcc5
ATP binding cassette subfamily C member 5
multiple interactions
ISO
Benzbromarone inhibits the reaction [ABCC5 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]
CTD
PMID:31348918
NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
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Abcc6
ATP binding cassette subfamily C member 6
multiple interactions affects expression decreases activity
ISO EXP
Benzbromarone inhibits the reaction [ABCC6 protein affects the transport of N-ethylmaleimide-S-glutathione] Benzbromarone affects the expression of ABCC6 mRNA Benzbromarone results in decreased activity of ABCC6 protein
CTD
PMID:11880368 PMID:14667841 PMID:19483382
NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
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Abcg5
ATP binding cassette subfamily G member 5
affects expression
EXP
Benzbromarone affects the expression of ABCG5 mRNA
CTD
PMID:19483382
NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
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Abhd1
abhydrolase domain containing 1
affects expression
EXP
Benzbromarone affects the expression of ABHD1 mRNA
CTD
PMID:19483382
NCBI chr 6:25,422,526...25,427,514
Ensembl chr 6:25,422,526...25,427,514
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Abhd14b
abhydrolase domain containing 14b
affects expression
EXP
Benzbromarone affects the expression of ABHD14B mRNA
CTD
PMID:19483382
NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119
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Abhd17a
abhydrolase domain containing 17A, depalmitoylase
affects expression
EXP
Benzbromarone affects the expression of ABHD17A mRNA
CTD
PMID:19483382
NCBI chr 7:9,124,332...9,132,762
Ensembl chr 7:9,124,332...9,130,762
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Acaca
acetyl-CoA carboxylase alpha
affects expression
EXP
Benzbromarone affects the expression of ACACA mRNA
CTD
PMID:19483382
NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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Acadl
acyl-CoA dehydrogenase, long chain
affects expression
EXP
Benzbromarone affects the expression of ACADL mRNA
CTD
PMID:19483382
NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
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Ace2
angiotensin converting enzyme 2
decreases expression
ISO
Benzbromarone results in decreased expression of ACE2 mRNA
CTD
PMID:32808185
NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
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Aco1
aconitase 1
affects expression
EXP
Benzbromarone affects the expression of ACO1 mRNA
CTD
PMID:19483382
NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
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Aco2
aconitase 2
affects expression
EXP
Benzbromarone affects the expression of ACO2 mRNA
CTD
PMID:19483382
NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
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Acot12
acyl-CoA thioesterase 12
affects expression
EXP
Benzbromarone affects the expression of ACOT12 mRNA
CTD
PMID:19483382
NCBI chr 2:22,986,867...23,027,538
Ensembl chr 2:22,986,626...23,027,536
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Acot4
acyl-CoA thioesterase 4
affects expression
EXP
Benzbromarone affects the expression of ACOT4 mRNA
CTD
PMID:19483382
NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917
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Adam15
ADAM metallopeptidase domain 15
affects expression
EXP
Benzbromarone affects the expression of ADAM15 mRNA
CTD
PMID:19483382
NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113
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Add1
adducin 1
affects expression
EXP
Benzbromarone affects the expression of ADD1 mRNA
CTD
PMID:19483382
NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182
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Adh4
alcohol dehydrogenase 4 (class II), pi polypeptide
affects expression
EXP
Benzbromarone affects the expression of ADH4 mRNA
CTD
PMID:19483382
NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591
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Adipoq
adiponectin, C1Q and collagen domain containing
multiple interactions increases expression
ISO
2-chloro-5-nitrobenzanilide inhibits the reaction [Benzbromarone results in increased expression of ADIPOQ mRNA] Benzbromarone results in increased expression of ADIPOQ protein
CTD
PMID:19048458 PMID:21329621
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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Adtrp
androgen-dependent TFPI-regulating protein
affects expression
EXP
Benzbromarone affects the expression of ADTRP mRNA
CTD
PMID:19483382
NCBI chr17:22,907,758...22,993,834
Ensembl chr17:22,930,740...22,993,826
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Afm
afamin
affects expression
EXP
Benzbromarone affects the expression of AFM mRNA
CTD
PMID:19483382
NCBI chr14:17,531,022...17,563,868
Ensembl chr14:17,531,024...17,563,870
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Agt
angiotensinogen
affects expression
EXP
Benzbromarone affects the expression of AGT mRNA
CTD
PMID:19483382
NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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Agtr1a
angiotensin II receptor, type 1a
affects expression
EXP
Benzbromarone affects the expression of AGTR1A mRNA
CTD
PMID:19483382
NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
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Akr1a1
aldo-keto reductase family 1 member A1
affects expression
EXP
Benzbromarone affects the expression of AKR1A1 mRNA
CTD
PMID:19483382
NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
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Akr1c1
aldo-keto reductase family 1, member C1
multiple interactions
ISO
Benzbromarone binds to and results in decreased activity of AKR1C1 protein
CTD
PMID:12604236
NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
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Akr1c2
aldo-keto reductase family 1, member C2
decreases activity
ISO
Benzbromarone results in decreased activity of AKR1C2 protein
CTD
PMID:12604236
NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
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Akr1c3
aldo-keto reductase family 1, member C3
decreases activity
ISO
Benzbromarone results in decreased activity of AKR1C3 protein
CTD
PMID:12604236
NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
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Akr7a2
aldo-keto reductase family 7, member A2
affects expression
EXP
Benzbromarone affects the expression of AKR7A2 mRNA
CTD
PMID:19483382
NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
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Akr7a3
aldo-keto reductase family 7 member A3
affects expression
EXP
Benzbromarone affects the expression of AKR7A3 mRNA
CTD
PMID:19483382
NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
affects expression
EXP
Benzbromarone affects the expression of ALDH1A1 mRNA
CTD
PMID:19483382
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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Aldh2
aldehyde dehydrogenase 2 family member
affects expression
EXP
Benzbromarone affects the expression of ALDH2 mRNA
CTD
PMID:19483382
NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
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Alkbh7
alkB homolog 7
affects expression
EXP
Benzbromarone affects the expression of ALKBH7 mRNA
CTD
PMID:19483382
NCBI chr 9:1,838,886...1,841,044
Ensembl chr 9:1,838,811...1,841,044
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Ap2m1
adaptor related protein complex 2 subunit mu 1
affects expression
EXP
Benzbromarone affects the expression of AP2M1 mRNA
CTD
PMID:19483382
NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
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Apcs
amyloid P component, serum
affects expression
EXP
Benzbromarone affects the expression of APCS mRNA
CTD
PMID:19483382
NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298
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Apoa4
apolipoprotein A4
affects expression
EXP
Benzbromarone affects the expression of APOA4 mRNA
CTD
PMID:19483382
NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
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Apoh
apolipoprotein H
affects expression
EXP
Benzbromarone affects the expression of APOH mRNA
CTD
PMID:19483382
NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
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Apool
apolipoprotein O-like
affects expression
EXP
Benzbromarone affects the expression of APOOL mRNA
CTD
PMID:19483382
NCBI chr X:77,377,723...77,443,672
Ensembl chr X:77,377,781...77,443,900
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Arg1
arginase 1
affects expression
EXP
Benzbromarone affects the expression of ARG1 mRNA
CTD
PMID:19483382
NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
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Arl6ip1
ADP-ribosylation factor like GTPase 6 interacting protein 1
affects expression
EXP
Benzbromarone affects the expression of ARL6IP1 mRNA
CTD
PMID:19483382
NCBI chr 1:172,430,475...172,439,990
Ensembl chr 1:172,430,489...172,439,994
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Asgr2
asialoglycoprotein receptor 2
affects expression
EXP
Benzbromarone affects the expression of ASGR2 mRNA
CTD
PMID:19483382
NCBI chr10:54,821,407...54,834,624
Ensembl chr10:54,821,438...54,834,617
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Atf5
activating transcription factor 5
affects expression
EXP
Benzbromarone affects the expression of ATF5 mRNA
CTD
PMID:19483382
NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
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Atp5f1e
ATP synthase F1 subunit epsilon
affects expression
EXP
Benzbromarone affects the expression of ATP5F1E mRNA
CTD
PMID:19483382
NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450
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Atp6ap2
ATPase H+ transporting accessory protein 2
affects expression
EXP
Benzbromarone affects the expression of ATP6AP2 mRNA
CTD
PMID:19483382
NCBI chr X:10,183,983...10,210,948
Ensembl chr X:10,183,068...10,210,918
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Atp6v1a
ATPase H+ transporting V1 subunit A
affects expression
EXP
Benzbromarone affects the expression of ATP6V1A mRNA
CTD
PMID:19483382
NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
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Atp6v1f
ATPase H+ transporting V1 subunit F
affects expression
EXP
Benzbromarone affects the expression of ATP6V1F mRNA
CTD
PMID:19483382
NCBI chr 4:58,067,666...58,070,628
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Baat
bile acid CoA:amino acid N-acyltransferase
affects expression
EXP
Benzbromarone affects the expression of BAAT mRNA
CTD
PMID:19483382
NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
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Bcl6b
BCL6B, transcription repressor
affects expression
EXP
Benzbromarone affects the expression of BCL6B mRNA
CTD
PMID:19483382
NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974
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Bltp3b
bridge-like lipid transfer protein family member 3B
affects expression
EXP
Benzbromarone affects the expression of BLTP3B mRNA
CTD
PMID:19483382
NCBI chr 7:24,181,635...24,261,720
Ensembl chr 7:24,181,644...24,261,720
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Bmf
Bcl2 modifying factor
affects expression
EXP
Benzbromarone affects the expression of BMF mRNA
CTD
PMID:19483382
NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
G
Bnip3
BCL2 interacting protein 3
affects expression
EXP
Benzbromarone affects the expression of BNIP3 mRNA
CTD
PMID:19483382
NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
G
Btf3
basic transcription factor 3
affects expression
EXP
Benzbromarone affects the expression of BTF3 mRNA
CTD
PMID:19483382
NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
G
C1qbp
complement C1q binding protein
affects expression
EXP
Benzbromarone affects the expression of C1QBP mRNA
CTD
PMID:19483382
NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649
G
C1s
complement C1s
affects expression
EXP
Benzbromarone affects the expression of C1S mRNA
CTD
PMID:19483382
NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
G
C2cd2
C2 calcium-dependent domain containing 2
affects expression
EXP
Benzbromarone affects the expression of C2CD2 mRNA
CTD
PMID:19483382
NCBI chr11:37,225,321...37,289,741
Ensembl chr11:37,227,415...37,289,739
G
C4bpa
complement component 4 binding protein, alpha
affects expression
EXP
Benzbromarone affects the expression of C4BPA mRNA
CTD
PMID:19483382
NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205
G
C7
complement C7
affects expression
EXP
Benzbromarone affects the expression of C7 mRNA
CTD
PMID:19483382
NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535
G
C8b
complement C8 beta chain
affects expression
EXP
Benzbromarone affects the expression of C8B mRNA
CTD
PMID:19483382
NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565
G
Cadps2
calcium dependent secretion activator 2
affects expression
EXP
Benzbromarone affects the expression of CADPS2 mRNA
CTD
PMID:19483382
NCBI chr 4:51,780,415...52,309,641
Ensembl chr 4:51,781,053...52,309,829
G
Caprin1
cell cycle associated protein 1
affects expression
EXP
Benzbromarone affects the expression of CAPRIN1 mRNA
CTD
PMID:19483382
NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502
G
Car2
carbonic anhydrase 2
affects expression
EXP
Benzbromarone affects the expression of CA2 mRNA
CTD
PMID:19483382
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
G
Car3
carbonic anhydrase 3
affects expression
EXP
Benzbromarone affects the expression of CAR3 mRNA
CTD
PMID:19483382
NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
G
Casp3
caspase 3
affects expression
EXP
Benzbromarone affects the expression of CASP3 mRNA
CTD
PMID:19483382
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
G
Cat
catalase
increases activity
EXP
Benzbromarone results in increased activity of CAT protein
CTD
PMID:2260096
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
G
Cbr1
carbonyl reductase 1
affects expression
EXP
Benzbromarone affects the expression of CBR1 mRNA
CTD
PMID:19483382
NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393
G
Cd36
CD36 molecule
increases expression
ISO
Benzbromarone results in increased expression of CD36 mRNA
CTD
PMID:19048458
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
G
Cdo1
cysteine dioxygenase type 1
affects expression
EXP
Benzbromarone affects the expression of CDO1 mRNA
CTD
PMID:19483382
NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
G
Cept1
choline/ethanolamine phosphotransferase 1
affects expression
EXP
Benzbromarone affects the expression of CEPT1 mRNA
CTD
PMID:19483382
NCBI chr 2:193,994,220...194,036,141
Ensembl chr 2:193,993,447...194,035,578
G
Ces2h
carboxylesterase 2H
affects expression
EXP
Benzbromarone affects the expression of CES2 mRNA
CTD
PMID:19483382
NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
G
Cfi
complement factor I
affects expression
EXP
Benzbromarone affects the expression of CFI mRNA
CTD
PMID:19483382
NCBI chr 2:218,389,079...218,430,565
Ensembl chr 2:218,387,990...218,430,561
G
Chp1
calcineurin-like EF-hand protein 1
affects expression
EXP
Benzbromarone affects the expression of CHP1 mRNA
CTD
PMID:19483382
NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251
G
Cisd1
CDGSH iron sulfur domain 1
affects expression
EXP
Benzbromarone affects the expression of CISD1 mRNA
CTD
PMID:19483382
NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924
G
Clcn4
chloride voltage-gated channel 4
affects expression
EXP
Benzbromarone affects the expression of CLCN4 mRNA
CTD
PMID:19483382
NCBI chr X:23,729,194...23,795,391
Ensembl chr X:23,729,338...23,793,238
G
Clpp
caseinolytic mitochondrial matrix peptidase proteolytic subunit
affects expression
EXP
Benzbromarone affects the expression of CLPP mRNA
CTD
PMID:19483382
NCBI chr 9:1,831,680...1,837,700
Ensembl chr 9:1,830,311...1,837,693
G
Clptm1l
CLPTM1-like
affects expression
EXP
Benzbromarone affects the expression of CLPTM1L mRNA
CTD
PMID:19483382
NCBI chr 1:29,667,545...29,683,530
Ensembl chr 1:29,667,545...29,683,530
G
Cmbl
carboxymethylenebutenolidase homolog
affects expression
EXP
Benzbromarone affects the expression of CMBL mRNA
CTD
PMID:19483382
NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009
G
Cmpk1
cytidine/uridine monophosphate kinase 1
affects expression
EXP
Benzbromarone affects the expression of CMPK1 mRNA
CTD
PMID:19483382
NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830
G
Copg1
COPI coat complex subunit gamma 1
affects expression
EXP
Benzbromarone affects the expression of COPG1 mRNA
CTD
PMID:19483382
NCBI chr 4:120,366,540...120,392,502
Ensembl chr 4:120,366,542...120,415,616
G
Cops4
COP9 signalosome subunit 4
affects expression
EXP
Benzbromarone affects the expression of COPS4 mRNA
CTD
PMID:19483382
NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,078,576...9,108,887
G
Coq3
coenzyme Q3 methyltransferase
affects expression
EXP
Benzbromarone affects the expression of COQ3 mRNA
CTD
PMID:19483382
NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607
G
Cox4i1
cytochrome c oxidase subunit 4i1
affects expression
EXP
Benzbromarone affects the expression of COX4I1 mRNA
CTD
PMID:19483382
NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
G
Cpn1
carboxypeptidase N subunit 1
affects expression
EXP
Benzbromarone affects the expression of CPN1 mRNA
CTD
PMID:19483382
NCBI chr 1:242,844,575...242,873,465
Ensembl chr 1:242,844,212...242,873,465
G
Cpq
carboxypeptidase Q
affects expression
EXP
Benzbromarone affects the expression of CPQ mRNA
CTD
PMID:19483382
NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546
G
Cpt1a
carnitine palmitoyltransferase 1A
increases expression
ISO
Benzbromarone results in increased expression of CPT1A mRNA; Benzbromarone results in increased expression of CPT1A protein
CTD
PMID:25108121
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
G
Crem
cAMP responsive element modulator
affects expression
EXP
Benzbromarone affects the expression of CREM mRNA
CTD
PMID:19483382
NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
G
Crp
C-reactive protein
multiple interactions decreases expression
ISO
Benzbromarone inhibits the reaction [IL1B protein results in increased expression of CRP protein] Benzbromarone results in decreased expression of CRP protein
CTD
PMID:21329621
NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
G
Csnk2b
casein kinase 2 beta
affects expression
EXP
Benzbromarone affects the expression of CSNK2B mRNA
CTD
PMID:19483382
NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133
G
Csrp1
cysteine and glycine-rich protein 1
affects expression
EXP
Benzbromarone affects the expression of CSRP1 mRNA
CTD
PMID:19483382
NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
G
Ctnna1
catenin alpha 1
affects expression
EXP
Benzbromarone affects the expression of CTNNA1 mRNA
CTD
PMID:19483382
NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
decreases activity
ISO
Benzbromarone results in decreased activity of CYP1A1 protein
CTD
PMID:33814510
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
G
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
decreases activity
ISO
Benzbromarone results in decreased activity of CYP1B1 protein
CTD
PMID:33814510
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
G
Cyp2a1
cytochrome P450, family 2, subfamily a, polypeptide 1
affects expression
EXP
Benzbromarone affects the expression of CYP2A1 mRNA
CTD
PMID:19483382
NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
G
Cyp2b2
cytochrome P450, family 2, subfamily b, polypeptide 2
affects expression
EXP
Benzbromarone affects the expression of CYP2B2 mRNA
CTD
PMID:19483382
NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
G
Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
affects expression
EXP
Benzbromarone affects the expression of CYP2B3 mRNA
CTD
PMID:19483382
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
G
Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
multiple interactions
ISO
Benzbromarone analog binds to and results in decreased activity of CYP2C19 protein; Benzbromarone binds to and results in decreased activity of CYP2C19 protein
CTD
PMID:15615526
NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
G
Cyp2d3
cytochrome P450, family 2, subfamily d, polypeptide 3
affects expression
EXP
Benzbromarone affects the expression of CYP2D3 mRNA
CTD
PMID:19483382
NCBI chr 7:113,917,711...113,922,068
Ensembl chr 7:113,908,947...113,922,084
G
Cyp2d4
cytochrome P450, family 2, subfamily d, polypeptide 4
affects expression
EXP
Benzbromarone affects the expression of CYP2D4 mRNA
CTD
PMID:19483382
NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
G
Cyp2f4
cytochrome P450, family 2, subfamily f, polypeptide 4
affects expression
EXP
Benzbromarone affects the expression of CYP2F4 mRNA
CTD
PMID:19483382
NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896
G
Cyp2j4
cytochrome P450, family 2, subfamily j, polypeptide 4
affects expression
EXP
Benzbromarone affects the expression of CYP2J4 mRNA
CTD
PMID:19483382
NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
G
Cyp2t1
cytochrome P450, family 2, subfamily t, polypeptide 1
affects expression
EXP
Benzbromarone affects the expression of CYP2T1 mRNA
CTD
PMID:19483382
NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:82,446,921...82,451,563
G
Cyp3a23-3a1
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
affects expression
EXP
Benzbromarone affects the expression of CYP3A23-3A1 mRNA
CTD
PMID:19483382
NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 Ensembl chr12:9,254,475...9,285,030
G
Cyp3a9
cytochrome P450, family 3, subfamily a, polypeptide 9
affects expression
EXP
Benzbromarone affects the expression of CYP3A9 mRNA
CTD
PMID:19483382
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
G
Cyp4a8
cytochrome P450, family 4, subfamily a, polypeptide 8
affects expression
EXP
Benzbromarone affects the expression of CYP4A8 mRNA
CTD
PMID:19483382
NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:128,702,131...128,733,476
G
Cyp4f6
cytochrome P450, family 4, subfamily f, polypeptide 6
affects expression
EXP
Benzbromarone affects the expression of CYP4F6 mRNA
CTD
PMID:19483382
NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
G
Dbi
diazepam binding inhibitor
affects expression
EXP
Benzbromarone affects the expression of DBI mRNA
CTD
PMID:19483382
NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
G
Dcaf11
DDB1 and CUL4 associated factor 11
affects expression
EXP
Benzbromarone affects the expression of DCAF11 mRNA
CTD
PMID:19483382
NCBI chr15:29,046,744...29,057,450
Ensembl chr15:29,046,826...29,057,669
G
Dcxr
dicarbonyl and L-xylulose reductase
affects expression
EXP
Benzbromarone affects the expression of DCXR mRNA
CTD
PMID:19483382
NCBI chr10:106,006,404...106,008,293
G
Decr1
2,4-dienoyl-CoA reductase 1
affects expression
EXP
Benzbromarone affects the expression of DECR1 mRNA
CTD
PMID:19483382
NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
G
Dexi
Dexi homolog
affects expression
EXP
Benzbromarone affects the expression of DEXI mRNA
CTD
PMID:19483382
NCBI chr10:5,126,021...5,138,746
Ensembl chr10:5,137,288...5,138,738
G
Dgat1
diacylglycerol O-acyltransferase 1
affects expression
EXP
Benzbromarone affects the expression of DGAT1 mRNA
CTD
PMID:19483382
NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
G
Dhcr24
24-dehydrocholesterol reductase
affects expression
EXP
Benzbromarone affects the expression of DHCR24 mRNA
CTD
PMID:19483382
NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
G
Dhrs4
dehydrogenase/reductase 4
affects expression
EXP
Benzbromarone affects the expression of DHRS4 mRNA
CTD
PMID:19483382
NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127
G
Dhrs7b
dehydrogenase/reductase 7B
affects expression
EXP
Benzbromarone affects the expression of DHRS7B mRNA
CTD
PMID:19483382
NCBI chr10:45,504,344...45,537,094
Ensembl chr10:45,504,426...45,537,076
G
Dhx16
DEAH-box helicase 16
affects expression
EXP
Benzbromarone affects the expression of DHX16 mRNA
CTD
PMID:19483382
NCBI chr20:2,862,000...2,874,991
Ensembl chr20:2,862,000...2,874,948
G
Dmac2l
distal membrane arm assembly component 2 like
affects expression
EXP
Benzbromarone affects the expression of DMAC2L mRNA
CTD
PMID:19483382
NCBI chr 6:88,205,580...88,223,934
Ensembl chr 6:88,205,700...88,223,933
G
Dnajc3
DnaJ heat shock protein family (Hsp40) member C3
affects expression
EXP
Benzbromarone affects the expression of DNAJC3 mRNA
CTD
PMID:19483382
NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181
G
Dpp4
dipeptidylpeptidase 4
affects expression
EXP
Benzbromarone affects the expression of DPP4 mRNA
CTD
PMID:19483382
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
G
Dpyd
dihydropyrimidine dehydrogenase
affects expression
EXP
Benzbromarone affects the expression of DPYD mRNA
CTD
PMID:19483382
NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
G
Ears2
glutamyl-tRNA synthetase 2, mitochondrial
affects expression
EXP
Benzbromarone affects the expression of EARS2 mRNA
CTD
PMID:19483382
NCBI chr 1:176,597,986...176,625,848
Ensembl chr 1:176,597,986...176,625,836
G
Echs1
enoyl-CoA hydratase, short chain 1
affects expression
EXP
Benzbromarone affects the expression of ECHS1 mRNA
CTD
PMID:19483382
NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
G
Eci1
enoyl-CoA delta isomerase 1
affects expression
EXP
Benzbromarone affects the expression of ECI1 mRNA
CTD
PMID:19483382
NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
G
Eci2
enoyl-CoA delta isomerase 2
affects expression
EXP
Benzbromarone affects the expression of ECI2 mRNA
CTD
PMID:19483382
NCBI chr17:29,850,884...29,886,781
Ensembl chr17:29,870,391...29,886,781
G
Eef1g
eukaryotic translation elongation factor 1 gamma
affects expression
EXP
Benzbromarone affects the expression of EEF1G mRNA
CTD
PMID:19483382
NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382
G
Ehhadh
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
affects expression
EXP
Benzbromarone affects the expression of EHHADH mRNA
CTD
PMID:19483382
NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
G
Eif4a2
eukaryotic translation initiation factor 4A2
affects expression
EXP
Benzbromarone affects the expression of EIF4A2 mRNA
CTD
PMID:19483382
NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
G
Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
affects expression
EXP
Benzbromarone affects the expression of EIF4EBP1 mRNA
CTD
PMID:19483382
NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
G
Eif4h
eukaryotic translation initiation factor 4H
affects expression
EXP
Benzbromarone affects the expression of EIF4H mRNA
CTD
PMID:19483382
NCBI chr12:22,083,155...22,099,876
Ensembl chr12:22,082,835...22,099,876
G
Enc1
ectodermal-neural cortex 1
affects expression
EXP
Benzbromarone affects the expression of ENC1 mRNA
CTD
PMID:19483382
NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
G
Eno1
enolase 1
affects expression
EXP
Benzbromarone affects the expression of ENO1 mRNA
CTD
PMID:19483382
NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
G
Enpep
glutamyl aminopeptidase
affects expression
EXP
Benzbromarone affects the expression of ENPEP mRNA
CTD
PMID:19483382
NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947
G
Enpp1
ectonucleotide pyrophosphatase/phosphodiesterase 1
affects expression
EXP
Benzbromarone affects the expression of ENPP1 mRNA
CTD
PMID:19483382
NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
G
Epcam
epithelial cell adhesion molecule
affects expression
EXP
Benzbromarone affects the expression of EPCAM mRNA
CTD
PMID:19483382
NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
G
Erp29
endoplasmic reticulum protein 29
affects expression
EXP
Benzbromarone affects the expression of ERP29 mRNA
CTD
PMID:19483382
NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
G
Esd
esterase D
affects expression
EXP
Benzbromarone affects the expression of ESD mRNA
CTD
PMID:19483382
NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144
G
Etfb
electron transfer flavoprotein subunit beta
affects expression
EXP
Benzbromarone affects the expression of ETFB mRNA
CTD
PMID:19483382
NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068
G
Eya2
EYA transcriptional coactivator and phosphatase 2
decreases activity
ISO
Benzbromarone results in decreased activity of EYA2 protein
CTD
PMID:22545090
NCBI chr 3:154,335,598...154,519,006
Ensembl chr 3:154,335,400...154,518,793
G
Eya3
EYA transcriptional coactivator and phosphatase 3
decreases activity
ISO
Benzbromarone results in decreased activity of EYA3 protein
CTD
PMID:22545090
NCBI chr 5:144,806,523...144,934,522
Ensembl chr 5:144,806,577...144,934,518
G
Faah
fatty acid amide hydrolase
affects expression
EXP
Benzbromarone affects the expression of FAAH mRNA
CTD
PMID:19483382
NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677
G
Fabp4
fatty acid binding protein 4
increases expression
ISO
Benzbromarone results in increased expression of FABP4 mRNA
CTD
PMID:19048458
NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
G
Fads2
fatty acid desaturase 2
affects expression
EXP
Benzbromarone affects the expression of FADS2 mRNA
CTD
PMID:19483382
NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
G
Fbp1
fructose-bisphosphatase 1
affects expression
EXP
Benzbromarone affects the expression of FBP1 mRNA
CTD
PMID:19483382
NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
G
Fdft1
farnesyl diphosphate farnesyl transferase 1
affects expression
EXP
Benzbromarone affects the expression of FDFT1 mRNA
CTD
PMID:19483382
NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
G
Fdps
farnesyl diphosphate synthase
affects expression
EXP
Benzbromarone affects the expression of FDPS mRNA
CTD
PMID:19483382
NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
G
Fdx2
ferredoxin 2
affects expression
EXP
Benzbromarone affects the expression of FDX2 mRNA
CTD
PMID:19483382
NCBI chr 8:19,604,916...19,609,832
Ensembl chr 8:19,604,916...19,609,849
G
Fmo1
flavin containing dimethylaniline monoxygenase 1
affects expression
EXP
Benzbromarone affects the expression of FMO1 mRNA
CTD
PMID:19483382
NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
G
Gamt
guanidinoacetate N-methyltransferase
affects expression
EXP
Benzbromarone affects the expression of GAMT mRNA
CTD
PMID:19483382
NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:9,448,628...9,451,778
G
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
affects expression
EXP
Benzbromarone affects the expression of GAPDH mRNA
CTD
PMID:19483382
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
G
Gbe1
1,4-alpha-glucan branching enzyme 1
affects expression
EXP
Benzbromarone affects the expression of GBE1 mRNA
CTD
PMID:19483382
NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210
G
Gchfr
GTP cyclohydrolase I feedback regulator
affects expression
EXP
Benzbromarone affects the expression of GCHFR mRNA
CTD
PMID:19483382
NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080
G
Ggh
gamma-glutamyl hydrolase
affects expression
EXP
Benzbromarone affects the expression of GGH mRNA
CTD
PMID:19483382
NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787
G
Gjb1
gap junction protein, beta 1
affects expression
EXP
Benzbromarone affects the expression of GJB1 mRNA
CTD
PMID:19483382
NCBI chr X:66,501,848...66,509,783
Ensembl chr X:66,501,820...66,509,925
G
Gpld1
glycosylphosphatidylinositol specific phospholipase D1
affects expression
EXP
Benzbromarone affects the expression of GPLD1 mRNA
CTD
PMID:19483382
NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
G
Gpx1
glutathione peroxidase 1
affects expression
EXP
Benzbromarone affects the expression of GPX1 mRNA
CTD
PMID:19483382
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
G
Gpx4
glutathione peroxidase 4
affects expression
EXP
Benzbromarone affects the expression of GPX4 mRNA
CTD
PMID:19483382
NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
G
Grina
glutamate ionotropic receptor NMDA type subunit associated protein 1
affects expression
EXP
Benzbromarone affects the expression of GRINA mRNA
CTD
PMID:19483382
NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366
G
Grpel1
GrpE-like 1, mitochondrial
affects expression
EXP
Benzbromarone affects the expression of GRPEL1 mRNA
CTD
PMID:19483382
NCBI chr14:74,292,023...74,298,243
Ensembl chr14:74,292,023...74,298,200
G
Gstt1
glutathione S-transferase theta 1
affects expression
EXP
Benzbromarone affects the expression of GSTT1 mRNA
CTD
PMID:19483382
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
G
Gtf2h5
general transcription factor IIH subunit 5
affects expression
EXP
Benzbromarone affects the expression of GTF2H5 mRNA
CTD
PMID:19483382
NCBI chr 1:46,656,804...46,663,512
Ensembl chr 1:46,656,859...46,664,939
G
Gzma
granzyme A
affects expression
EXP
Benzbromarone affects the expression of GZMA mRNA
CTD
PMID:19483382
NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493
G
H3f3b
H3.3 histone B
affects expression
EXP
Benzbromarone affects the expression of H3F3B mRNA
CTD
PMID:19483382
NCBI chr10:101,256,484...101,258,716
Ensembl chr10:101,256,480...101,258,709
G
Hal
histidine ammonia lyase
affects expression
EXP
Benzbromarone affects the expression of HAL mRNA
CTD
PMID:19483382
NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
G
Hao2
hydroxyacid oxidase 2
affects expression
EXP
Benzbromarone affects the expression of HAO2 mRNA
CTD
PMID:19483382
NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425
G
Hba-a2
hemoglobin alpha, adult chain 2
affects expression
EXP
Benzbromarone affects the expression of HBA-A2 mRNA
CTD
PMID:19483382
NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392
G
Hbb
hemoglobin subunit beta
affects expression
EXP
Benzbromarone affects the expression of HBB mRNA
CTD
PMID:19483382
NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
G
Hdc
histidine decarboxylase
affects expression
EXP
Benzbromarone affects the expression of HDC mRNA
CTD
PMID:19483382
NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
G
Hgd
homogentisate 1, 2-dioxygenase
affects expression
EXP
Benzbromarone affects the expression of HGD mRNA
CTD
PMID:19483382
NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323
G
Hmgn1
high mobility group nucleosome binding domain 1
affects expression
EXP
Benzbromarone affects the expression of HMGN1 mRNA
CTD
PMID:19483382
NCBI chr11:35,422,328...35,428,247
Ensembl chr11:35,422,328...35,428,254
G
Hprt1
hypoxanthine phosphoribosyltransferase 1
affects expression
EXP
Benzbromarone affects the expression of HPRT1 mRNA
CTD
PMID:19483382
NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154
G
Hps5
HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
affects expression
EXP
Benzbromarone affects the expression of HPS5 mRNA
CTD
PMID:19483382
NCBI chr 1:97,281,626...97,320,945
Ensembl chr 1:97,247,598...97,321,019
G
Hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
affects expression
EXP
Benzbromarone affects the expression of HSD17B4 mRNA
CTD
PMID:19483382
NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
G
Hsdl2
hydroxysteroid dehydrogenase like 2
affects expression
EXP
Benzbromarone affects the expression of HSDL2 mRNA
CTD
PMID:19483382
NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
G
Htra1
HtrA serine peptidase 1
affects expression
EXP
Benzbromarone affects the expression of HTRA1 mRNA
CTD
PMID:19483382
NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379
G
Igf1
insulin-like growth factor 1
affects expression
EXP
Benzbromarone affects the expression of IGF1 mRNA
CTD
PMID:19483382
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
G
Igfals
insulin-like growth factor binding protein, acid labile subunit
affects expression
EXP
Benzbromarone affects the expression of IGFALS mRNA
CTD
PMID:19483382
NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677
G
Igfbp2
insulin-like growth factor binding protein 2
affects expression
EXP
Benzbromarone affects the expression of IGFBP2 mRNA
CTD
PMID:19483382
NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
G
Il1a
interleukin 1 alpha
multiple interactions
ISO
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone
CTD
PMID:19362101
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
G
Il1b
interleukin 1 beta
multiple interactions
ISO
Benzbromarone inhibits the reaction [IL1B protein results in increased expression of CRP protein]
CTD
PMID:21329621
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il6
interleukin 6
multiple interactions
ISO
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone
CTD
PMID:19362101
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Impa1
inositol monophosphatase 1
affects expression
EXP
Benzbromarone affects the expression of IMPA1 mRNA
CTD
PMID:19483382
NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:91,462,799...91,484,313
G
Inhbe
inhibin subunit beta E
affects expression
EXP
Benzbromarone affects the expression of INHBE mRNA
CTD
PMID:19483382
NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
G
Isyna1
inositol-3-phosphate synthase 1
affects expression
EXP
Benzbromarone affects the expression of ISYNA1 mRNA
CTD
PMID:19483382
NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979
G
Itih4
inter-alpha-trypsin inhibitor heavy chain 4
affects expression
EXP
Benzbromarone affects the expression of ITIH4 mRNA
CTD
PMID:19483382
NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708
G
Iyd
iodotyrosine deiodinase
decreases activity
ISO
Benzbromarone results in decreased activity of IYD protein
CTD
PMID:24012475
NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
G
Jak1
Janus kinase 1
affects expression
EXP
Benzbromarone affects the expression of JAK1 mRNA
CTD
PMID:19483382
NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
G
Kdelr2
KDEL endoplasmic reticulum protein retention receptor 2
affects expression
EXP
Benzbromarone affects the expression of KDELR2 mRNA
CTD
PMID:19483382
NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153
G
Kdr
kinase insert domain receptor
affects expression
EXP
Benzbromarone affects the expression of KDR mRNA
CTD
PMID:19483382
NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
G
Krt8
keratin 8
affects expression
EXP
Benzbromarone affects the expression of KRT8 mRNA
CTD
PMID:19483382
NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
G
Lcat
lecithin cholesterol acyltransferase
affects expression
EXP
Benzbromarone affects the expression of LCAT mRNA
CTD
PMID:19483382
NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
G
Lcmt1
leucine carboxyl methyltransferase 1
affects expression
EXP
Benzbromarone affects the expression of LCMT1 mRNA
CTD
PMID:19483382
NCBI chr 1:177,904,119...177,960,111
Ensembl chr 1:177,904,139...177,960,112
G
Lipc
lipase C, hepatic type
affects expression
EXP
Benzbromarone affects the expression of LIPC mRNA
CTD
PMID:19483382
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
G
Lox
lysyl oxidase
affects expression
EXP
Benzbromarone affects the expression of LOX mRNA
CTD
PMID:19483382
NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
G
Lpl
lipoprotein lipase
increases expression
ISO
Benzbromarone results in increased expression of LPL protein
CTD
PMID:18274627
NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
G
Lrp3
LDL receptor related protein 3
affects expression
EXP
Benzbromarone affects the expression of LRP3 mRNA
CTD
PMID:19483382
NCBI chr 1:87,843,815...87,859,147
Ensembl chr 1:87,844,868...87,859,110
G
Man2b1
mannosidase, alpha, class 2B, member 1
affects expression
EXP
Benzbromarone affects the expression of MAN2B1 mRNA
CTD
PMID:19483382
NCBI chr19:23,055,092...23,074,398
Ensembl chr19:23,055,097...23,074,389
G
Map2k2
mitogen activated protein kinase kinase 2
affects expression
EXP
Benzbromarone affects the expression of MAP2K2 mRNA
CTD
PMID:19483382
NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
G
Masp2
MBL associated serine protease 2
affects expression
EXP
Benzbromarone affects the expression of MASP2 mRNA
CTD
PMID:19483382
NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580
G
Me1
malic enzyme 1
affects expression
EXP
Benzbromarone affects the expression of ME1 mRNA
CTD
PMID:19483382
NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
G
Mmut
methylmalonyl-CoA mutase
affects expression
EXP
Benzbromarone affects the expression of MMUT mRNA
CTD
PMID:19483382
NCBI chr 9:19,928,720...19,956,985
Ensembl chr 9:19,928,727...19,957,046
G
Mro
maestro
affects expression
EXP
Benzbromarone affects the expression of MRO mRNA
CTD
PMID:19483382
NCBI chr18:67,450,186...67,467,593
Ensembl chr18:67,450,595...67,467,044
G
Mrpl2
mitochondrial ribosomal protein L2
affects expression
EXP
Benzbromarone affects the expression of MRPL2 mRNA
CTD
PMID:19483382
NCBI chr 9:14,333,233...14,337,006
Ensembl chr 9:14,333,234...14,337,040
G
mrpl9
mitochondrial ribosomal protein L9
affects expression
EXP
Benzbromarone affects the expression of MRPL9 mRNA
CTD
PMID:19483382
NCBI chr 2:182,082,012...182,086,758
Ensembl chr 2:182,076,369...182,087,095
G
Mug2
murinoglobulin 2
affects expression
EXP
Benzbromarone affects the expression of PZP mRNA
CTD
PMID:19483382
NCBI chr 4:155,164,061...155,236,894
Ensembl chr 4:155,164,011...155,236,475
G
Myadm
myeloid-associated differentiation marker
affects expression
EXP
Benzbromarone affects the expression of MYADM mRNA
CTD
PMID:19483382
NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:65,864,173...65,874,035
G
Mycbp2
MYC binding protein 2
affects expression
EXP
Benzbromarone affects the expression of MYCBP2 mRNA
CTD
PMID:19483382
NCBI chr15:79,937,354...80,175,432
Ensembl chr15:79,937,354...80,175,498
G
Myo1d
myosin ID
affects expression
EXP
Benzbromarone affects the expression of MYO1D mRNA
CTD
PMID:19483382
NCBI chr10:65,489,153...65,765,812
Ensembl chr10:65,489,154...65,766,349
G
Naa38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
affects expression
EXP
Benzbromarone affects the expression of NAA38 mRNA
CTD
PMID:19483382
NCBI chr10:54,117,754...54,118,913
Ensembl chr10:54,117,163...54,119,494
G
Nap1l1
nucleosome assembly protein 1-like 1
affects expression
EXP
Benzbromarone affects the expression of NAP1L1 mRNA
CTD
PMID:19483382
NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
G
Nat8
N-acetyltransferase 8
affects expression
EXP
Benzbromarone affects the expression of NAT8 mRNA
CTD
PMID:19483382
NCBI chr 4:118,279,521...118,284,671
Ensembl chr 4:118,270,954...118,281,763
G
Ndrg2
NDRG family member 2
affects expression
EXP
Benzbromarone affects the expression of NDRG2 mRNA
CTD
PMID:19483382
NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626
G
Ndufs5
NADH:ubiquinone oxidoreductase subunit S5
affects expression
EXP
Benzbromarone affects the expression of NDUFS5 mRNA
CTD
PMID:19483382
NCBI chr 5:135,974,029...135,979,705
Ensembl chr 5:135,974,034...135,979,603 Ensembl chr14:135,974,034...135,979,603 Ensembl chr 2:135,974,034...135,979,603
G
Ndufv3
NADH:ubiquinone oxidoreductase subunit V3
affects expression
EXP
Benzbromarone affects the expression of NDUFV3 mRNA
CTD
PMID:19483382
NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074 Ensembl chr13:9,612,431...9,623,074
G
Neu2
neuraminidase 2
affects expression
EXP
Benzbromarone affects the expression of NEU2 mRNA
CTD
PMID:19483382
NCBI chr 9:88,218,494...88,267,356
Ensembl chr 9:88,249,135...88,267,355
G
Nfx1
nuclear transcription factor, X-box binding 1
affects expression
EXP
Benzbromarone affects the expression of NFX1 mRNA
CTD
PMID:19483382
NCBI chr 5:56,104,945...56,162,912
Ensembl chr 5:56,105,234...56,162,912
G
Nipal2
NIPA-like domain containing 2
affects expression
EXP
Benzbromarone affects the expression of NIPAL2 mRNA
CTD
PMID:19483382
NCBI chr 7:65,774,477...65,884,807
Ensembl chr 7:65,774,477...65,884,807
G
Nit1
nitrilase 1
affects expression
EXP
Benzbromarone affects the expression of NIT1 mRNA
CTD
PMID:19483382
NCBI chr13:83,769,888...83,773,324
Ensembl chr13:83,765,941...83,773,332
G
Nme2
NME/NM23 nucleoside diphosphate kinase 2
affects expression
EXP
Benzbromarone affects the expression of NME2 mRNA
CTD
PMID:19483382
NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538
G
Nr1i3
nuclear receptor subfamily 1, group I, member 3
affects expression
EXP
Benzbromarone affects the expression of NR1I3 mRNA
CTD
PMID:19483382
NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
G
Nr3c1
nuclear receptor subfamily 3, group C, member 1
affects expression
EXP
Benzbromarone affects the expression of NR3C1 mRNA
CTD
PMID:19483382
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
G
Oaf
out at first homolog
affects expression
EXP
Benzbromarone affects the expression of OAF mRNA
CTD
PMID:19483382
NCBI chr 8:43,594,362...43,612,334
Ensembl chr 8:43,594,363...43,612,334
G
Obp3
alpha-2u globulin PGCL4
affects expression
EXP
Benzbromarone affects the expression of OBP3 mRNA
CTD
PMID:19483382
NCBI chr 5:74,842,316...74,845,858
Ensembl chr 5:74,842,316...74,845,757
G
Ogdh
oxoglutarate dehydrogenase
affects expression
EXP
Benzbromarone affects the expression of OGDH mRNA
CTD
PMID:19483382
NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
G
Olr59
olfactory receptor 59
affects expression
EXP
Benzbromarone affects the expression of OLR59 mRNA
CTD
PMID:19483382
NCBI chr 1:157,193,051...157,227,707
Ensembl chr 1:157,193,080...157,211,179
G
Ostc
oligosaccharyltransferase complex non-catalytic subunit
affects expression
EXP
Benzbromarone affects the expression of OSTC mRNA
CTD
PMID:19483382
NCBI chr 2:219,250,549...219,266,076
Ensembl chr 2:219,236,952...219,266,107
G
Otc
ornithine transcarbamylase
affects expression
EXP
Benzbromarone affects the expression of OTC mRNA
CTD
PMID:19483382
NCBI chr X:12,453,834...12,529,954
Ensembl chr X:12,453,834...12,566,918
G
Pabpc4
poly(A) binding protein, cytoplasmic 4
affects expression
EXP
Benzbromarone affects the expression of PABPC4 mRNA
CTD
PMID:19483382
NCBI chr 5:135,563,142...135,578,985
Ensembl chr 5:135,563,562...135,578,979
G
Paics
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
affects expression
EXP
Benzbromarone affects the expression of PAICS mRNA
CTD
PMID:19483382
NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635
G
Pc
pyruvate carboxylase
affects expression
EXP
Benzbromarone affects the expression of PCX mRNA
CTD
PMID:19483382
NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
G
Pccb
propionyl-CoA carboxylase subunit beta
affects expression
EXP
Benzbromarone affects the expression of PCCB mRNA
CTD
PMID:19483382
NCBI chr 8:101,591,218...101,641,213
Ensembl chr 8:101,590,737...101,641,234
G
Pcsk6
proprotein convertase subtilisin/kexin type 6
affects expression
EXP
Benzbromarone affects the expression of PCSK6 mRNA
CTD
PMID:19483382
NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:119,429,265...119,627,596
G
Pctp
phosphatidylcholine transfer protein
affects expression
EXP
Benzbromarone affects the expression of PCTP mRNA
CTD
PMID:19483382
NCBI chr10:74,808,887...74,856,260
Ensembl chr10:74,808,887...74,849,867
G
Pdcl3
phosducin-like 3
affects expression
EXP
Benzbromarone affects the expression of PDCL3 mRNA
CTD
PMID:19483382
NCBI chr 9:41,234,322...41,243,769
Ensembl chr 9:41,234,234...41,243,735
G
Pdia3
protein disulfide isomerase family A, member 3
affects expression
EXP
Benzbromarone affects the expression of PDIA3 mRNA
CTD
PMID:19483382
NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
G
Pdia6
protein disulfide isomerase family A, member 6
affects expression
EXP
Benzbromarone affects the expression of PDIA6 mRNA
CTD
PMID:19483382
NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
G
Pex19
peroxisomal biogenesis factor 19
affects expression
EXP
Benzbromarone affects the expression of PEX19 mRNA
CTD
PMID:19483382
NCBI chr13:84,592,277...84,608,793
Ensembl chr13:84,592,312...84,608,608
G
Pgam1
phosphoglycerate mutase 1
affects expression
EXP
Benzbromarone affects the expression of PGAM1 mRNA
CTD
PMID:19483382
NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
G
Pgrmc1
progesterone receptor membrane component 1
affects expression
EXP
Benzbromarone affects the expression of PGRMC1 mRNA
CTD
PMID:19483382
NCBI chr X:115,832,865...115,841,060
Ensembl chr X:115,832,884...115,888,682
G
Phyh
phytanoyl-CoA 2-hydroxylase
affects expression
EXP
Benzbromarone affects the expression of PHYH mRNA
CTD
PMID:19483382
NCBI chr17:73,329,461...73,346,359
Ensembl chr17:73,329,082...73,346,409
G
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
affects expression
EXP
Benzbromarone affects the expression of PIGP mRNA
CTD
PMID:19483382
NCBI chr11:33,682,943...33,689,111
Ensembl chr11:33,682,948...33,689,321
G
Pklr
pyruvate kinase L/R
affects expression
EXP
Benzbromarone affects the expression of PKLR mRNA
CTD
PMID:19483382
NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
G
Plbd1
phospholipase B domain containing 1
affects expression
EXP
Benzbromarone affects the expression of PLBD1 mRNA
CTD
PMID:19483382
NCBI chr 4:169,472,983...169,529,277
Ensembl chr 4:169,472,983...169,529,277
G
Plg
plasminogen
affects expression
EXP
Benzbromarone affects the expression of PLG mRNA
CTD
PMID:19483382
NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786
G
Pls3
plastin 3
affects expression
EXP
Benzbromarone affects the expression of PLS3 mRNA
CTD
PMID:19483382
NCBI chr X:111,589,193...111,683,908
Ensembl chr X:111,589,254...111,683,891
G
Pon2
paraoxonase 2
affects expression
EXP
Benzbromarone affects the expression of PON2 mRNA
CTD
PMID:19483382
NCBI chr 4:33,389,702...33,425,186
Ensembl chr 4:33,389,714...33,425,248
G
Pparg
peroxisome proliferator-activated receptor gamma
affects expression
ISO
Benzbromarone affects the expression of PPARG mRNA
CTD
PMID:19048458
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
G
Ppdpf
pancreatic progenitor cell differentiation and proliferation factor
affects expression
EXP
Benzbromarone affects the expression of PPDPF mRNA
CTD
PMID:19483382
NCBI chr 3:168,299,309...168,301,040
Ensembl chr 3:168,299,791...168,301,036
G
Prdx2
peroxiredoxin 2
affects expression
EXP
Benzbromarone affects the expression of PRDX2 mRNA
CTD
PMID:19483382
NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
G
Prdx6
peroxiredoxin 6
affects expression
EXP
Benzbromarone affects the expression of PRDX6 mRNA
CTD
PMID:19483382
NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
G
Proc
protein C, inactivator of coagulation factors Va and VIIIa
affects expression
EXP
Benzbromarone affects the expression of PROC mRNA
CTD
PMID:19483382
NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133
G
Prpsap1
phosphoribosyl pyrophosphate synthetase-associated protein 1
affects expression
EXP
Benzbromarone affects the expression of PRPSAP1 mRNA
CTD
PMID:19483382
NCBI chr10:101,701,094...101,750,753
Ensembl chr10:101,701,096...101,750,751
G
Psma6
proteasome 20S subunit alpha 6
affects expression
EXP
Benzbromarone affects the expression of PSMA6 mRNA
CTD
PMID:19483382
NCBI chr 6:72,765,534...72,796,554
Ensembl chr 6:72,765,473...72,796,554
G
Psmb1
proteasome 20S subunit beta 1
affects expression
EXP
Benzbromarone affects the expression of PSMB1 mRNA
CTD
PMID:19483382
NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560
G
Psmb3
proteasome 20S subunit beta 3
affects expression
EXP
Benzbromarone affects the expression of PSMB3 mRNA
CTD
PMID:19483382
NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521
G
Psmc1
proteasome 26S subunit, ATPase 1
affects expression
EXP
Benzbromarone affects the expression of PSMC1 mRNA
CTD
PMID:19483382
NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123
G
Psmc3
proteasome 26S subunit, ATPase 3
affects expression
EXP
Benzbromarone affects the expression of PSMC3 mRNA
CTD
PMID:19483382
NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358
G
Psmc5
proteasome 26S subunit, ATPase 5
affects expression
EXP
Benzbromarone affects the expression of PSMC5 mRNA
CTD
PMID:19483382
NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135
G
Psmd1
proteasome 26S subunit, non-ATPase 1
affects expression
EXP
Benzbromarone affects the expression of PSMD1 mRNA
CTD
PMID:19483382
NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211
G
Psmd4
proteasome 26S subunit ubiquitin receptor, non-ATPase 4
affects expression
EXP
Benzbromarone affects the expression of PSMD4 mRNA
CTD
PMID:19483382
NCBI chr 2:182,598,934...182,608,250
Ensembl chr 2:182,598,934...182,608,194
G
Ptms
parathymosin
affects expression
EXP
Benzbromarone affects the expression of PTMS mRNA
CTD
PMID:19483382
NCBI chr 4:157,722,384...157,726,575
Ensembl chr 4:157,722,386...157,727,009
G
Ptprf
protein tyrosine phosphatase, receptor type, F
affects expression
EXP
Benzbromarone affects the expression of PTPRF mRNA
CTD
PMID:19483382
NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
G
Pttg1ip
PTTG1 interacting protein
affects expression
EXP
Benzbromarone affects the expression of PTTG1IP mRNA
CTD
PMID:19483382
NCBI chr20:11,030,013...11,047,742
Ensembl chr20:11,030,015...11,047,316
G
Pygl
glycogen phosphorylase L
affects expression
EXP
Benzbromarone affects the expression of PYGL mRNA
CTD
PMID:19483382
NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
G
Rab5if
RAB5 interacting factor
affects expression
EXP
Benzbromarone affects the expression of RAB5IF mRNA
CTD
PMID:19483382
NCBI chr 3:145,357,990...145,368,012
Ensembl chr 3:145,357,861...145,368,012
G
Rida
reactive intermediate imine deaminase A homolog
affects expression
EXP
Benzbromarone affects the expression of RIDA mRNA
CTD
PMID:19483382
NCBI chr 7:65,691,429...65,705,257
Ensembl chr 7:65,691,435...65,705,716
G
Rnase4
ribonuclease A family member 4
affects expression
EXP
Benzbromarone affects the expression of RNASE4 mRNA
CTD
PMID:19483382
NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117
G
Rnf103
ring finger protein 103
affects expression
EXP
Benzbromarone affects the expression of RNF103 mRNA
CTD
PMID:19483382
NCBI chr 4:103,526,456...103,542,529
Ensembl chr 4:103,526,502...103,555,919
G
Rnps1
RNA binding protein with serine rich domain 1
affects expression
EXP
Benzbromarone affects the expression of RNPS1 mRNA
CTD
PMID:19483382
NCBI chr10:13,445,516...13,455,858
Ensembl chr10:13,445,653...13,455,858
G
Rpl11
ribosomal protein L11
affects expression
EXP
Benzbromarone affects the expression of RPL11 mRNA
CTD
PMID:19483382
NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599
G
Rpl13
ribosomal protein L13
affects expression
EXP
Benzbromarone affects the expression of RPL13 mRNA
CTD
PMID:19483382
NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014
G
Rpl15
ribosomal protein L15
affects expression
EXP
Benzbromarone affects the expression of RPL15 mRNA
CTD
PMID:19483382
NCBI chr15:7,503,883...7,507,166
Ensembl chr15:7,503,883...7,507,165
G
Rpl17
ribosomal protein L17
affects expression
EXP
Benzbromarone affects the expression of RPL17 mRNA
CTD
PMID:19483382
NCBI chr18:68,581,141...68,584,253
Ensembl chr18:68,581,098...68,584,253
G
Rpl23
ribosomal protein L23
affects expression
EXP
Benzbromarone affects the expression of RPL23 mRNA
CTD
PMID:19483382
NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870
G
Rpl3
ribosomal protein L3
affects expression
EXP
Benzbromarone affects the expression of RPL3 mRNA
CTD
PMID:19483382
NCBI chr 7:111,622,255...111,627,640
Ensembl chr 7:111,621,610...111,636,468
G
Rpl32
ribosomal protein L32
affects expression
EXP
Benzbromarone affects the expression of RPL32 mRNA
CTD
PMID:19483382
NCBI chr 4:148,864,048...148,867,612
Ensembl chr 4:148,864,044...148,867,612
G
Rpl4
ribosomal protein L4
affects expression
EXP
Benzbromarone affects the expression of RPL4 mRNA
CTD
PMID:19483382
NCBI chr 8:64,671,177...64,676,301
Ensembl chr 8:64,671,160...64,676,306
G
Rpn2
ribophorin II
affects expression
EXP
Benzbromarone affects the expression of RPN2 mRNA
CTD
PMID:19483382
NCBI chr 3:145,941,787...145,989,271
Ensembl chr 3:145,941,839...145,989,543
G
Rps14
ribosomal protein S14
affects expression
EXP
Benzbromarone affects the expression of RPS14 mRNA
CTD
PMID:19483382
NCBI chr18:54,227,854...54,232,638
Ensembl chr18:54,227,854...54,233,166
G
Rps18
ribosomal protein S18
affects expression
EXP
Benzbromarone affects the expression of RPS18 mRNA
CTD
PMID:19483382
NCBI chr20:4,931,427...4,935,538
Ensembl chr10:101,204,500...101,205,146 Ensembl chr20:101,204,500...101,205,146
G
Rps19
ribosomal protein S19
affects expression
EXP
Benzbromarone affects the expression of RPS19 mRNA
CTD
PMID:19483382
NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508
G
Rps20
ribosomal protein S20
affects expression
EXP
Benzbromarone affects the expression of RPS20 mRNA
CTD
PMID:19483382
NCBI chr 5:16,819,095...16,820,476
Ensembl chr 5:16,819,304...16,820,475 Ensembl chr 9:16,819,304...16,820,475 Ensembl chr 3:16,819,304...16,820,475
G
Rps3a
ribosomal protein S3a
affects expression
EXP
Benzbromarone affects the expression of RPS3A mRNA
CTD
PMID:19483382
NCBI chr 2:171,524,685...171,529,054
Ensembl chr 2:171,524,500...171,529,055
G
Rps6
ribosomal protein S6
affects expression
EXP
Benzbromarone affects the expression of RPS6 mRNA
CTD
PMID:19483382
NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602 Ensembl chr 5:101,371,136...101,374,602
G
Rps8
ribosomal protein S8
affects expression
EXP
Benzbromarone affects the expression of RPS8 mRNA
CTD
PMID:19483382
NCBI chr 5:130,630,362...130,632,932
Ensembl chr 5:130,629,716...130,633,268
G
Rras2
RAS related 2
affects expression
EXP
Benzbromarone affects the expression of RRAS2 mRNA
CTD
PMID:19483382
NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111
G
RT1-S3
RT1 class Ib, locus S3
affects expression
EXP
Benzbromarone affects the expression of RT1-S3 mRNA
CTD
PMID:19483382
NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
G
S1pr1
sphingosine-1-phosphate receptor 1
affects expression
EXP
Benzbromarone affects the expression of S1PR1 mRNA
CTD
PMID:19483382
NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
G
Sbspon
somatomedin B and thrombospondin, type 1 domain containing
affects expression
EXP
Benzbromarone affects the expression of SBSPON mRNA
CTD
PMID:19483382
NCBI chr 5:3,402,763...3,433,338
Ensembl chr 5:3,402,648...3,435,420
G
Sdc2
syndecan 2
affects expression
EXP
Benzbromarone affects the expression of SDC2 mRNA
CTD
PMID:19483382
NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081
G
Sdhc
succinate dehydrogenase complex subunit C
affects expression
EXP
Benzbromarone affects the expression of SDHC mRNA
CTD
PMID:19483382
NCBI chr13:83,544,652...83,565,560
Ensembl chr13:83,544,652...83,566,253
G
Sdhd
succinate dehydrogenase complex subunit D
affects expression
EXP
Benzbromarone affects the expression of SDHD mRNA
CTD
PMID:19483382
NCBI chr 8:50,944,702...50,954,298
Ensembl chr 8:50,944,704...50,954,238
G
Serinc3
serine incorporator 3
affects expression
EXP
Benzbromarone affects the expression of SERINC3 mRNA
CTD
PMID:19483382
NCBI chr 3:152,301,882...152,321,327
Ensembl chr 3:152,301,772...152,321,808
G
Serpina1
serpin family A member 1
affects expression
EXP
Benzbromarone affects the expression of SERPINA1 mRNA
CTD
PMID:19483382
NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
G
Serpina10
serpin family A member 10
affects expression
EXP
Benzbromarone affects the expression of SERPINA10 mRNA
CTD
PMID:19483382
NCBI chr 6:122,756,106...122,764,544
Ensembl chr 6:122,756,108...122,764,544
G
Serpina4
serpin family A member 4
affects expression
EXP
Benzbromarone affects the expression of SERPINA4 mRNA
CTD
PMID:19483382
NCBI chr 6:122,999,970...123,009,083
Ensembl chr 6:122,999,900...123,009,082
G
Serpinf2
serpin family F member 2
affects expression
EXP
Benzbromarone affects the expression of SERPINF2 mRNA
CTD
PMID:19483382
NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243
G
Sfxn1
sideroflexin 1
affects expression
EXP
Benzbromarone affects the expression of SFXN1 mRNA
CTD
PMID:19483382
NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529
G
Shmt2
serine hydroxymethyltransferase 2
affects expression
EXP
Benzbromarone affects the expression of SHMT2 mRNA
CTD
PMID:19483382
NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
G
Slc22a1
solute carrier family 22 member 1
affects expression
EXP
Benzbromarone affects the expression of SLC22A1 mRNA
CTD
PMID:19483382
NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
G
Slc22a12
solute carrier family 22 member 12
affects activity decreases activity multiple interactions affects response to substance
ISO EXP
Benzbromarone affects the activity of SLC22A12 protein Benzbromarone results in decreased activity of SLC22A12 protein Benzbromarone inhibits the reaction [SLC22A12 protein affects the transport of Uric Acid] SLC22A12 protein affects the susceptibility to Benzbromarone Benzbromarone inhibits the reaction [SLC22A12 protein results in increased uptake of Oxypurinol]; Benzbromarone inhibits the reaction [SLC22A12 protein results in increased uptake of Uric Acid]
CTD
PMID:14694169 PMID:14747372 PMID:16135657 PMID:18670416 PMID:20486468 PMID:21074513 PMID:21272127 PMID:21449597 More...
NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555
G
Slc22a6
solute carrier family 22 member 6
multiple interactions
ISO
Benzbromarone inhibits the reaction [SLC22A6 protein affects the transport of Uric Acid]
CTD
PMID:12472777
NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
G
Slc23a1
solute carrier family 23 member 1
affects expression
EXP
Benzbromarone affects the expression of SLC23A1 mRNA
CTD
PMID:19483382
NCBI chr18:27,214,940...27,230,564
Ensembl chr18:27,216,281...27,230,697
G
Slc25a13
solute carrier family 25 member 13
affects expression
EXP
Benzbromarone affects the expression of SLC25A13 mRNA
CTD
PMID:19483382
NCBI chr 4:34,179,224...34,361,912
Ensembl chr 4:34,179,224...34,361,902
G
Slc25a3
solute carrier family 25 member 3
affects expression
EXP
Benzbromarone affects the expression of SLC25A3 mRNA
CTD
PMID:19483382
NCBI chr 7:25,611,937...25,619,401
Ensembl chr 7:25,586,725...25,667,727
G
Slc27a2
solute carrier family 27 member 2
affects expression
EXP
Benzbromarone affects the expression of SLC27A2 mRNA
CTD
PMID:19483382
NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
G
Slc2a9
solute carrier family 2 member 9
multiple interactions
ISO
Benzbromarone inhibits the reaction [SLC2A9 protein results in increased uptake of Uric Acid] Benzbromarone inhibits the reaction [SLC2A9 protein alternative form results in increased transport of Uric Acid]
CTD
PMID:18842065 PMID:19587147
NCBI chr14:72,328,334...72,461,981
Ensembl chr14:72,328,320...72,461,981
G
Slc39a8
solute carrier family 39 member 8
affects expression
EXP
Benzbromarone affects the expression of SLC39A8 mRNA
CTD
PMID:19483382
NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129
G
Slc46a1
solute carrier family 46 member 1
affects expression
EXP
Benzbromarone affects the expression of SLC46A1 mRNA
CTD
PMID:19483382
NCBI chr10:63,361,504...63,367,940
Ensembl chr10:63,361,486...63,368,848
G
Slc66a2
solute carrier family 66 member 2
affects expression
EXP
Benzbromarone affects the expression of SLC66A2 mRNA
CTD
PMID:19483382
NCBI chr18:73,702,472...73,739,678
Ensembl chr18:73,702,564...73,739,676
G
Slc6a6
solute carrier family 6 member 6
affects expression
EXP
Benzbromarone affects the expression of SLC6A6 mRNA
CTD
PMID:19483382
NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
G
Sod2
superoxide dismutase 2
increases expression
ISO
Benzbromarone results in increased expression of SOD2 mRNA
CTD
PMID:25108121
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
G
Sppl2a
signal peptide peptidase-like 2A
affects expression
EXP
Benzbromarone affects the expression of SPPL2A mRNA
CTD
PMID:19483382
NCBI chr 3:114,149,337...114,193,408
Ensembl chr 3:114,151,069...114,193,264
G
Srm
spermidine synthase
affects expression
EXP
Benzbromarone affects the expression of SRM mRNA
CTD
PMID:19483382
NCBI chr 5:159,025,875...159,029,076
Ensembl chr 5:159,025,873...159,029,405
G
Srprb
SRP receptor subunit beta
affects expression
EXP
Benzbromarone affects the expression of SRPRB mRNA
CTD
PMID:19483382
NCBI chr 8:103,768,685...103,782,632
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Ssx2ip
SSX family member 2 interacting protein
affects expression
EXP
Benzbromarone affects the expression of SSX2IP mRNA
CTD
PMID:19483382
NCBI chr 2:235,298,012...235,330,750
Ensembl chr 2:235,298,088...235,330,745
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St3gal6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
affects expression
EXP
Benzbromarone affects the expression of ST3GAL6 mRNA
CTD
PMID:19483382
NCBI chr11:42,061,282...42,121,801
Ensembl chr11:42,077,621...42,121,776
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St6gal1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
affects expression
EXP
Benzbromarone affects the expression of ST6GAL1 mRNA
CTD
PMID:19483382
NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310
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Suclg1
succinate-CoA ligase GDP/ADP-forming subunit alpha
affects expression
EXP
Benzbromarone affects the expression of SUCLG1 mRNA
CTD
PMID:19483382
NCBI chr 4:105,308,236...105,337,595
Ensembl chr 4:105,308,039...105,337,600
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Surf4
surfeit 4
affects expression
EXP
Benzbromarone affects the expression of SURF4 mRNA
CTD
PMID:19483382
NCBI chr 3:10,248,360...10,261,537
Ensembl chr 3:10,241,837...10,263,315
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Synj2bp
synaptojanin 2 binding protein
affects expression
EXP
Benzbromarone affects the expression of SYNJ2BP mRNA
CTD
PMID:19483382
NCBI chr 6:101,189,714...101,227,400
Ensembl chr 6:101,189,714...101,227,406
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Tgfbi
transforming growth factor, beta induced
affects expression
EXP
Benzbromarone affects the expression of TGFBI mRNA
CTD
PMID:19483382
NCBI chr17:7,955,603...7,984,903
Ensembl chr17:7,955,603...7,985,240
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Thnsl2
threonine synthase-like 2
affects expression
EXP
Benzbromarone affects the expression of THNSL2 mRNA
CTD
PMID:19483382
NCBI chr 4:103,112,974...103,132,122
Ensembl chr 4:103,112,963...103,132,017
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Timm21
translocase of inner mitochondrial membrane 21
affects expression
EXP
Benzbromarone affects the expression of TIMM21 mRNA
CTD
PMID:19483382
NCBI chr18:78,314,900...78,319,362
Ensembl chr18:78,314,909...78,319,454
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Tkfc
triokinase and FMN cyclase
affects expression
EXP
Benzbromarone affects the expression of TKFC mRNA
CTD
PMID:19483382
NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737
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Tmbim1
transmembrane BAX inhibitor motif containing 1
affects expression
EXP
Benzbromarone affects the expression of TMBIM1 mRNA
CTD
PMID:19483382
NCBI chr 9:75,871,835...75,889,366
Ensembl chr 9:75,871,835...75,889,069
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Tmco1
transmembrane and coiled-coil domains 1
affects expression
EXP
Benzbromarone affects the expression of TMCO1 mRNA
CTD
PMID:19483382
NCBI chr13:79,460,229...79,483,557
Ensembl chr13:79,460,135...79,483,555
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Tmed2
transmembrane p24 trafficking protein 2
affects expression
EXP
Benzbromarone affects the expression of TMED2 mRNA
CTD
PMID:19483382
NCBI chr12:32,052,542...32,061,628
Ensembl chr12:32,052,543...32,071,903
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Tmed7
transmembrane p24 trafficking protein 7
affects expression
EXP
Benzbromarone affects the expression of TMED7 mRNA
CTD
PMID:19483382
NCBI chr18:39,318,564...39,325,640
Ensembl chr18:39,297,351...39,325,640
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Tmem123
transmembrane protein 123
affects expression
EXP
Benzbromarone affects the expression of TMEM123 mRNA
CTD
PMID:19483382
NCBI chr 8:4,922,077...4,952,228
Ensembl chr 8:4,922,098...4,952,224
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Tmem97
transmembrane protein 97
affects expression
EXP
Benzbromarone affects the expression of TMEM97 mRNA
CTD
PMID:19483382
NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730
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Tnf
tumor necrosis factor
increases expression multiple interactions
ISO
Benzbromarone results in increased expression of TNF protein [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone
CTD
PMID:19362101 PMID:19933411
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Txn1
thioredoxin 1
affects expression
EXP
Benzbromarone affects the expression of TXN1 mRNA
CTD
PMID:19483382
NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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Txnl1
thioredoxin-like 1
affects expression
EXP
Benzbromarone affects the expression of TXNL1 mRNA
CTD
PMID:19483382
NCBI chr18:57,125,362...57,155,167
Ensembl chr18:57,125,369...57,165,266
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Uba52
ubiquitin A-52 residue ribosomal protein fusion product 1
affects expression
EXP
Benzbromarone affects the expression of UBA52 mRNA
CTD
PMID:19483382
NCBI chr16:18,918,614...18,920,807
Ensembl chr16:18,900,616...18,920,807
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Ube2n
ubiquitin-conjugating enzyme E2N
affects expression
EXP
Benzbromarone affects the expression of UBE2N mRNA
CTD
PMID:19483382
NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
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Ufd1
ubiquitin recognition factor in ER associated degradation 1
affects expression
EXP
Benzbromarone affects the expression of UFD1 mRNA
CTD
PMID:19483382
NCBI chr11:82,161,618...82,185,107
Ensembl chr11:82,161,619...82,185,087
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Ugt1a1
UDP glucuronosyltransferase family 1 member A1
affects expression
EXP
Benzbromarone affects the expression of UGT1A1 mRNA
CTD
PMID:19483382
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Uqcr11
ubiquinol-cytochrome c reductase, complex III subunit XI
affects expression
EXP
Benzbromarone affects the expression of UQCR11 mRNA
CTD
PMID:19483382
NCBI chr 7:9,305,042...9,309,753
Ensembl chr 7:9,305,058...9,309,750
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Vnn1
vanin 1
affects expression
EXP
Benzbromarone affects the expression of VNN1 mRNA
CTD
PMID:19483382
NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
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Wdr26
WD repeat domain 26
affects expression
EXP
Benzbromarone affects the expression of WDR26 mRNA
CTD
PMID:19483382
NCBI chr13:92,930,282...92,972,061
Ensembl chr13:92,930,285...92,977,295
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Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
affects expression
EXP
Benzbromarone affects the expression of YWHAG mRNA
CTD
PMID:19483382
NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827
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Zdhhc23
zinc finger DHHC-type palmitoyltransferase 23
affects expression
EXP
Benzbromarone affects the expression of ZDHHC23 mRNA
CTD
PMID:19483382
NCBI chr11:56,718,702...56,735,063
Ensembl chr11:56,718,826...56,734,194
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Zwint
ZW10 interacting kinetochore protein
affects expression
EXP
Benzbromarone affects the expression of ZWINT mRNA
CTD
PMID:19483382
NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
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Tslp
thymic stromal lymphopoietin
multiple interactions
ISO
Phloxine O inhibits the reaction [calcipotriol increases expression of Tslp mRNA and protein in skin of external ear and phorbol 12-myristate 13-acetate increases expression of Tslp protein in keratinocytes]
RGD
PMID:29310423
RGD:38549374
NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548
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Aars1
alanyl-tRNA synthetase 1
increases expression
ISO
thifluzamide results in increased expression of AARS1 mRNA
CTD
PMID:33512557
NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
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Akt1
AKT serine/threonine kinase 1
decreases expression
ISO
thifluzamide results in decreased expression of AKT1 mRNA
CTD
PMID:33512557
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Aldh7a1
aldehyde dehydrogenase 7 family, member A1
decreases expression
ISO
thifluzamide results in decreased expression of ALDH7A1 mRNA
CTD
PMID:33512557
NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193
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Aldoa
aldolase, fructose-bisphosphate A
increases expression
ISO
thifluzamide results in increased expression of ALDOA mRNA
CTD
PMID:33512557
NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
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Anxa2
annexin A2
decreases expression
ISO
thifluzamide results in decreased expression of ANXA2 mRNA
CTD
PMID:33512557
NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
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Arhgap8
Rho GTPase activating protein 8
increases expression
ISO
thifluzamide results in increased expression of ARHGAP8 mRNA
CTD
PMID:33512557
NCBI chr 7:115,842,223...115,902,094
Ensembl chr 7:115,850,654...115,902,093
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Arhgap9
Rho GTPase activating protein 9
increases expression
ISO
thifluzamide results in increased expression of ARHGAP9 mRNA
CTD
PMID:33512557
NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524
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Arhgef2
Rho/Rac guanine nucleotide exchange factor 2
increases expression
ISO
thifluzamide results in increased expression of ARHGEF2 mRNA
CTD
PMID:33512557
NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355
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Arid4a
AT-rich interaction domain 4A
decreases expression
ISO
thifluzamide results in decreased expression of ARID4A mRNA
CTD
PMID:33512557
NCBI chr 6:89,522,459...89,593,868
Ensembl chr 6:89,522,442...89,593,510
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Arrdc4
arrestin domain containing 4
decreases expression
ISO
thifluzamide results in decreased expression of ARRDC4 mRNA
CTD
PMID:33512557
NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290
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Arsg
arylsulfatase G
increases expression
ISO
thifluzamide results in increased expression of ARSG mRNA
CTD
PMID:33512557
NCBI chr10:94,412,261...94,551,224
Ensembl chr10:94,447,399...94,542,941
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Asns
asparagine synthetase (glutamine-hydrolyzing)
increases expression
ISO
thifluzamide results in increased expression of ASNS mRNA
CTD
PMID:33512557
NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
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Ass1
argininosuccinate synthase 1
increases expression
ISO
thifluzamide results in increased expression of ASS1 mRNA
CTD
PMID:33512557
NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
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Atf4
activating transcription factor 4
increases expression
ISO
thifluzamide results in increased expression of ATF4 mRNA
CTD
PMID:33512557
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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Atf5
activating transcription factor 5
increases expression
ISO
thifluzamide results in increased expression of ATF5 mRNA
CTD
PMID:33512557
NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
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Aurkb
aurora kinase B
increases expression
ISO
thifluzamide results in increased expression of AURKB mRNA
CTD
PMID:33512557
NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
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Bid
BH3 interacting domain death agonist
decreases expression
ISO
thifluzamide results in decreased expression of BID mRNA
CTD
PMID:33512557
NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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Birc2
baculoviral IAP repeat-containing 2
decreases expression
ISO
thifluzamide results in decreased expression of BIRC2 mRNA
CTD
PMID:33512557
NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
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Birc5
baculoviral IAP repeat-containing 5
increases expression
ISO
thifluzamide results in increased expression of BIRC5 mRNA
CTD
PMID:33512557
NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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Bmf
Bcl2 modifying factor
decreases expression
ISO
thifluzamide results in decreased expression of BMF mRNA
CTD
PMID:33512557
NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
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Bphl
biphenyl hydrolase like
decreases expression
ISO
thifluzamide results in decreased expression of BPHL mRNA
CTD
PMID:33512557
NCBI chr17:30,800,939...30,837,277
Ensembl chr17:30,799,629...30,837,288
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Bsg
basigin (Ok blood group)
increases expression
ISO
thifluzamide results in increased expression of BSG mRNA
CTD
PMID:33512557
NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387
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C1d
C1D nuclear receptor corepressor
increases expression
ISO
thifluzamide results in increased expression of C1D mRNA
CTD
PMID:33512557
NCBI chr14:91,660,951...91,673,177
Ensembl chr14:91,660,989...91,672,852
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C2cd5
C2 calcium-dependent domain containing 5
decreases expression
ISO
thifluzamide results in decreased expression of C2CD5 mRNA
CTD
PMID:33512557
NCBI chr 4:175,969,544...176,055,597
Ensembl chr 4:175,969,545...176,055,558
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Camk2b
calcium/calmodulin-dependent protein kinase II beta
decreases expression
ISO
thifluzamide results in decreased expression of CAMK2B mRNA
CTD
PMID:33512557
NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
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Cars1
cysteinyl-tRNA synthetase 1
increases expression
ISO
thifluzamide results in increased expression of CARS1 mRNA
CTD
PMID:33512557
NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941
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Cbx4
chromobox 4
increases expression
ISO
thifluzamide results in increased expression of CBX4 mRNA
CTD
PMID:33512557
NCBI chr10:104,337,140...104,343,210
Ensembl chr10:104,336,876...104,356,706
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Ccnb2
cyclin B2
increases expression
ISO
thifluzamide results in increased expression of CCNB2 mRNA
CTD
PMID:33512557
NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
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Ccne2
cyclin E2
decreases expression
ISO
thifluzamide results in decreased expression of CCNE2 mRNA
CTD
PMID:33512557
NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
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Cd24
CD24 molecule
decreases expression
ISO
thifluzamide results in decreased expression of CD24 mRNA
CTD
PMID:33512557
NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
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Cdh10
cadherin 10
decreases expression
ISO
thifluzamide results in decreased expression of CDH10 mRNA
CTD
PMID:33512557
NCBI chr 2:68,628,623...68,850,995
Ensembl chr 2:68,628,780...68,850,995
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Cdk1
cyclin-dependent kinase 1
increases expression
ISO
thifluzamide results in increased expression of CDK1 mRNA
CTD
PMID:33512557
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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Cdk5
cyclin-dependent kinase 5
decreases expression
ISO
thifluzamide results in decreased expression of CDK5 mRNA
CTD
PMID:33512557
NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
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Cdkn3
cyclin-dependent kinase inhibitor 3
increases expression
ISO
thifluzamide results in increased expression of CDKN3 mRNA
CTD
PMID:33512557
NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
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Cebpb
CCAAT/enhancer binding protein beta
increases expression
ISO
thifluzamide results in increased expression of CEBPB mRNA
CTD
PMID:33512557
NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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Cep55
centrosomal protein 55
increases expression
ISO
thifluzamide results in increased expression of CEP55 mRNA
CTD
PMID:33512557
NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394
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Chac1
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
increases expression
ISO
thifluzamide results in increased expression of CHAC1 mRNA
CTD
PMID:33512557
NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
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Chka
choline kinase alpha
increases expression
ISO
thifluzamide results in increased expression of CHKA mRNA
CTD
PMID:33512557
NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
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Chrna4
cholinergic receptor nicotinic alpha 4 subunit
decreases expression
ISO
thifluzamide results in decreased expression of CHRNA4 mRNA
CTD
PMID:33512557
NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
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Cks2
CDC28 protein kinase regulatory subunit 2
increases expression
ISO
thifluzamide results in increased expression of CKS2 mRNA
CTD
PMID:33512557
NCBI chr17:13,570,611...13,575,770
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Cldn5
claudin 5
decreases expression
ISO
thifluzamide results in decreased expression of CLDN5 mRNA
CTD
PMID:33512557
NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992
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Clic4
chloride intracellular channel 4
increases expression
ISO
thifluzamide results in increased expression of CLIC4 mRNA
CTD
PMID:33512557
NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452
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Cpne3
copine 3
decreases expression
ISO
thifluzamide results in decreased expression of CPNE3 mRNA
CTD
PMID:33512557
NCBI chr 5:33,014,658...33,063,934
Ensembl chr 5:33,016,307...33,063,934
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Cpsf4
cleavage and polyadenylation specific factor 4
decreases expression
ISO
thifluzamide results in decreased expression of CPSF4 mRNA
CTD
PMID:33512557
NCBI chr12:9,429,765...9,445,586
Ensembl chr12:9,429,523...9,445,586
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Creg1
cellular repressor of E1A-stimulated genes 1
increases expression
ISO
thifluzamide results in increased expression of CREG1 mRNA
CTD
PMID:33512557
NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308
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Crtap
cartilage associated protein
increases expression
ISO
thifluzamide results in increased expression of CRTAP mRNA
CTD
PMID:33512557
NCBI chr 8:114,047,929...114,067,636
Ensembl chr 8:114,047,933...114,067,631
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Cth
cystathionine gamma-lyase
increases expression
ISO
thifluzamide results in increased expression of CTH mRNA
CTD
PMID:33512557
NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
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Ctnnd1
catenin delta 1
decreases expression
ISO
thifluzamide results in decreased expression of CTNND1 mRNA
CTD
PMID:33512557
NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516
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Ctss
cathepsin S
decreases expression
ISO
thifluzamide results in decreased expression of CTSS mRNA
CTD
PMID:33512557
NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483
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Cxcr4
C-X-C motif chemokine receptor 4
decreases expression
ISO
thifluzamide results in decreased expression of CXCR4 mRNA
CTD
PMID:33512557
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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Daam1
dishevelled associated activator of morphogenesis 1
decreases expression
ISO
thifluzamide results in decreased expression of DAAM1 mRNA
CTD
PMID:33512557
NCBI chr 6:90,389,544...90,550,114
Ensembl chr 6:90,389,688...90,550,114
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Dcx
doublecortin
decreases expression
ISO
thifluzamide results in decreased expression of DCX mRNA
CTD
PMID:33512557
NCBI chr X:107,430,767...107,573,612
Ensembl chr X:107,430,767...107,507,476
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Ddc
dopa decarboxylase
decreases expression
ISO
thifluzamide results in decreased expression of DDC mRNA
CTD
PMID:33512557
NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
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Ddit3
DNA-damage inducible transcript 3
increases expression
ISO
thifluzamide results in increased expression of DDIT3 mRNA
CTD
PMID:33512557
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Ddit4
DNA-damage-inducible transcript 4
increases expression
ISO
thifluzamide results in increased expression of DDIT4 mRNA
CTD
PMID:33512557
NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
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Depdc1b
DEP domain containing 1B
increases expression
ISO
thifluzamide results in increased expression of DEPDC1B mRNA
CTD
PMID:33512557
NCBI chr 2:39,891,163...39,963,779
Ensembl chr 2:39,891,481...39,963,779
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Dnm1
dynamin 1
decreases expression
ISO
thifluzamide results in decreased expression of DNM1 mRNA
CTD
PMID:33512557
NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538
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Dpm2
dolichyl-phosphate mannosyltransferase subunit 2, regulatory
increases expression
ISO
thifluzamide results in increased expression of DPM2 mRNA
CTD
PMID:33512557
NCBI chr 3:15,855,952...15,858,867
Ensembl chr 3:15,856,182...15,869,165 Ensembl chr 3:15,856,182...15,869,165
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Drd2
dopamine receptor D2
decreases expression
ISO
thifluzamide results in decreased expression of DRD2 mRNA
CTD
PMID:33512557
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
G
Dusp14
dual specificity phosphatase 14
increases expression
ISO
thifluzamide results in increased expression of DUSP14 mRNA
CTD
PMID:33512557
NCBI chr10:68,936,483...68,966,347
Ensembl chr10:68,935,330...68,965,329
G
Dusp22
dual specificity phosphatase 22
increases expression
ISO
thifluzamide results in increased expression of DUSP22 mRNA
CTD
PMID:33512557
NCBI chr17:33,780,980...33,831,241
Ensembl chr17:33,780,981...33,831,321
G
Dusp4
dual specificity phosphatase 4
increases expression
ISO
thifluzamide results in increased expression of DUSP4 mRNA
CTD
PMID:33512557
NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
G
Eea1
early endosome antigen 1
increases expression
ISO
thifluzamide results in increased expression of EEA1 mRNA
CTD
PMID:33512557
NCBI chr 7:30,554,686...30,722,186
Ensembl chr 7:30,554,552...30,718,487
G
Egr1
early growth response 1
increases expression
ISO
thifluzamide results in increased expression of EGR1 mRNA
CTD
PMID:33512557
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
G
Eif1
eukaryotic translation initiation factor 1
increases expression
ISO
thifluzamide results in increased expression of EIF1 mRNA
CTD
PMID:33512557
NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327
G
Eif2s2
eukaryotic translation initiation factor 2 subunit beta
increases expression
ISO
thifluzamide results in increased expression of EIF2S2 mRNA
CTD
PMID:33512557
NCBI chr 3:143,374,652...143,395,460
Ensembl chr 3:143,373,686...143,395,432
G
Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
increases expression
ISO
thifluzamide results in increased expression of EIF4EBP1 mRNA
CTD
PMID:33512557
NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
G
Elmod1
ELMO domain containing 1
decreases expression
ISO
thifluzamide results in decreased expression of ELMOD1 mRNA
CTD
PMID:33512557
NCBI chr 8:54,298,363...54,355,348
Ensembl chr 8:54,298,363...54,355,140
G
Ephb2
Eph receptor B2
decreases expression
ISO
thifluzamide results in decreased expression of EPHB2 mRNA
CTD
PMID:33512557
NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059
G
Eps15
epidermal growth factor receptor pathway substrate 15
increases expression
ISO
thifluzamide results in increased expression of EPS15 mRNA
CTD
PMID:33512557
NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221
G
Ero1a
endoplasmic reticulum oxidoreductase 1 alpha
increases expression
ISO
thifluzamide results in increased expression of ERO1A mRNA
CTD
PMID:33512557
NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
G
Etnk1
ethanolamine kinase 1
decreases expression
ISO
thifluzamide results in decreased expression of ETNK1 mRNA
CTD
PMID:33512557
NCBI chr 4:176,126,056...176,170,325
Ensembl chr 4:176,126,180...176,193,770
G
Ets1
ETS proto-oncogene 1, transcription factor
increases expression
ISO
thifluzamide results in increased expression of ETS1 mRNA
CTD
PMID:33512557
NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
G
Etv1
ETS variant transcription factor 1
decreases expression
ISO
thifluzamide results in decreased expression of ETV1 mRNA
CTD
PMID:33512557
NCBI chr 6:55,590,149...55,681,784
Ensembl chr 6:55,590,234...55,681,775
G
Exosc4
exosome component 4
decreases expression
ISO
thifluzamide results in decreased expression of EXOSC4 mRNA
CTD
PMID:33512557
NCBI chr 7:108,047,831...108,050,573
Ensembl chr 7:108,047,831...108,050,573
G
Exosc8
exosome component 8
increases expression
ISO
thifluzamide results in increased expression of EXOSC8 mRNA
CTD
PMID:33512557
NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928
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Fam72a
family with sequence similarity 72, member A
increases expression
ISO
thifluzamide results in increased expression of FAM72A mRNA
CTD
PMID:33512557
NCBI chr13:42,967,701...42,979,083
Ensembl chr13:42,967,578...42,984,208
G
Fgf8
fibroblast growth factor 8
decreases expression
ISO
thifluzamide results in decreased expression of FGF8 mRNA
CTD
PMID:33512557
NCBI chr 1:244,584,477...244,590,578
Ensembl chr 1:244,584,652...244,590,359
G
Fibin
fin bud initiation factor homolog
increases expression
ISO
thifluzamide results in increased expression of FIBIN mRNA
CTD
PMID:33512557
NCBI chr 3:96,942,405...96,944,676
Ensembl chr 3:96,942,406...96,944,676
G
Flna
filamin A
increases expression
ISO
thifluzamide results in increased expression of FLNA mRNA
CTD
PMID:33512557
NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052
G
Fth1
ferritin heavy chain 1
increases expression
ISO
thifluzamide results in increased expression of FTH1 mRNA
CTD
PMID:33512557
NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
G
Ftl1
ferritin light chain 1
increases expression
ISO
thifluzamide results in increased expression of FTL mRNA
CTD
PMID:33512557
NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725
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Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression
ISO
thifluzamide results in increased expression of GADD45A mRNA
CTD
PMID:33512557
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
G
Gadd45b
growth arrest and DNA-damage-inducible, beta
increases expression
ISO
thifluzamide results in increased expression of GADD45B mRNA
CTD
PMID:33512557
NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
G
Galnt3
polypeptide N-acetylgalactosaminyltransferase 3
decreases expression
ISO
thifluzamide results in decreased expression of GALNT3 mRNA
CTD
PMID:33512557
NCBI chr 3:50,742,500...50,779,266
Ensembl chr 3:50,742,512...50,766,268
G
Gclm
glutamate cysteine ligase, modifier subunit
increases expression
ISO
thifluzamide results in increased expression of GCLM mRNA
CTD
PMID:33512557
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
G
Gdf15
growth differentiation factor 15
increases expression
ISO
thifluzamide results in increased expression of GDF15 mRNA
CTD
PMID:33512557
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
G
Gldc
glycine decarboxylase
decreases expression
ISO
thifluzamide results in decreased expression of GLDC mRNA
CTD
PMID:33512557
NCBI chr 1:227,883,249...227,962,119
Ensembl chr 1:227,883,249...227,962,097
G
Glrx
glutaredoxin
decreases expression
ISO
thifluzamide results in decreased expression of GLRX mRNA
CTD
PMID:33512557
NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
G
Gmip
Gem-interacting protein
decreases expression
ISO
thifluzamide results in decreased expression of GMIP mRNA
CTD
PMID:33512557
NCBI chr16:19,600,723...19,614,459
Ensembl chr16:19,600,723...19,614,027
G
Gnai2
G protein subunit alpha i2
decreases expression
ISO
thifluzamide results in decreased expression of GNAI2 mRNA
CTD
PMID:33512557
NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
G
Gnb3
G protein subunit beta 3
decreases expression
ISO
thifluzamide results in decreased expression of GNB3 mRNA
CTD
PMID:33512557
NCBI chr 4:157,639,468...157,645,171
Ensembl chr 4:157,639,469...157,645,173
G
Got1
glutamic-oxaloacetic transaminase 1
increases expression
ISO
thifluzamide results in increased expression of GOT1 mRNA
CTD
PMID:33512557
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
G
Grb10
growth factor receptor bound protein 10
increases expression
ISO
thifluzamide results in increased expression of GRB10 mRNA
CTD
PMID:33512557
NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806
G
Gria2
glutamate ionotropic receptor AMPA type subunit 2
decreases expression
ISO
thifluzamide results in decreased expression of GRIA2 mRNA
CTD
PMID:33512557
NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
G
Grin2d
glutamate ionotropic receptor NMDA type subunit 2D
decreases expression
ISO
thifluzamide results in decreased expression of GRIN2D mRNA
CTD
PMID:33512557
NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793
G
Grm4
glutamate metabotropic receptor 4
decreases expression
ISO
thifluzamide results in decreased expression of GRM4 mRNA
CTD
PMID:33512557
NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821
G
Gsr
glutathione-disulfide reductase
increases expression
ISO
thifluzamide results in increased expression of GSR mRNA
CTD
PMID:33512557
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
G
Gstm2
glutathione S-transferase mu 2
decreases expression
ISO
thifluzamide results in decreased expression of GSTM2 mRNA
CTD
PMID:33512557
NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
G
H1f0
H1.0 linker histone
increases expression
ISO
thifluzamide results in increased expression of H1-0 mRNA
CTD
PMID:33512557
NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694
G
H1f2
H1.2 linker histone, cluster member
increases expression
ISO
thifluzamide results in increased expression of H1-2 mRNA
CTD
PMID:33512557
NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635
G
Herpud1
homocysteine inducible ER protein with ubiquitin like domain 1
increases expression
ISO
thifluzamide results in increased expression of HERPUD1 mRNA
CTD
PMID:33512557
NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
G
Hes5
hes family bHLH transcription factor 5
decreases expression
ISO
thifluzamide results in decreased expression of HES5 mRNA
CTD
PMID:33512557
NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001
G
Hhip
Hedgehog-interacting protein
increases expression
ISO
thifluzamide results in increased expression of HHIP mRNA
CTD
PMID:33512557
NCBI chr19:27,863,684...27,952,528
Ensembl chr19:27,863,213...27,952,528
G
Hist1h2ah
histone cluster 1 H2A family member H
increases expression
ISO
thifluzamide results in increased expression of H2AC11 mRNA
CTD
PMID:33512557
NCBI chr17:41,384,521...41,385,018
G
Hist1h2al1
histone cluster 1 H2A family like 1
increases expression
ISO
thifluzamide results in increased expression of H2AC6 mRNA
CTD
PMID:33512557
NCBI chr17:42,707,954...42,708,420
G
Hist1h2bd
histone cluster 1 H2B family member D
increases expression
ISO
thifluzamide results in increased expression of H2BC5 mRNA
CTD
PMID:33512557
NCBI chr17:42,792,887...42,793,268
G
Hmox1
heme oxygenase 1
increases expression
ISO
thifluzamide results in increased expression of HMOX1 mRNA
CTD
PMID:33512557
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Hnrnpm
heterogeneous nuclear ribonucleoprotein M
decreases expression
ISO
thifluzamide results in decreased expression of HNRNPM mRNA
CTD
PMID:33512557
NCBI chr 7:14,438,703...14,476,781
Ensembl chr 7:14,438,688...14,476,762
G
Hsd17b8
hydroxysteroid (17-beta) dehydrogenase 8
decreases expression
ISO
thifluzamide results in decreased expression of HSD17B8 mRNA
CTD
PMID:33512557
NCBI chr20:4,826,725...4,828,742
Ensembl chr20:4,822,026...4,828,742
G
Hspa8
heat shock protein family A (Hsp70) member 8
increases expression
ISO
thifluzamide results in increased expression of HSPA8 mRNA
CTD
PMID:33512557
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
G
Hyou1
hypoxia up-regulated 1
increases expression
ISO
thifluzamide results in increased expression of HYOU1 mRNA
CTD
PMID:33512557
NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
G
Ide
insulin degrading enzyme
increases expression
ISO
thifluzamide results in increased expression of IDE mRNA
CTD
PMID:33512557
NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440
G
Idh3a
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
increases expression
ISO
thifluzamide results in increased expression of IDH3A mRNA
CTD
PMID:33512557
NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084
G
Ifi44
interferon-induced protein 44
decreases expression
ISO
thifluzamide results in decreased expression of IFI44 mRNA
CTD
PMID:33512557
NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844
G
Ifitm2
interferon induced transmembrane protein 2
decreases expression
ISO
thifluzamide results in decreased expression of IFITM2 mRNA
CTD
PMID:33512557
NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741
G
Ifitm3
interferon induced transmembrane protein 3
decreases expression
ISO
thifluzamide results in decreased expression of IFITM3 mRNA
CTD
PMID:33512557
NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203
G
Ifrd1
interferon-related developmental regulator 1
increases expression
ISO
thifluzamide results in increased expression of IFRD1 mRNA
CTD
PMID:33512557
NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
G
Ikzf1
IKAROS family zinc finger 1
decreases expression
ISO
thifluzamide results in decreased expression of IKZF1 mRNA
CTD
PMID:33512557
NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416
G
Inhbe
inhibin subunit beta E
increases expression
ISO
thifluzamide results in increased expression of INHBE mRNA
CTD
PMID:33512557
NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
G
Ipo5
importin 5
increases expression
ISO
thifluzamide results in increased expression of IPO5 mRNA
CTD
PMID:33512557
NCBI chr15:97,990,755...98,041,074
Ensembl chr15:98,005,299...98,041,126
G
Irf1
interferon regulatory factor 1
increases expression
ISO
thifluzamide results in increased expression of IRF1 mRNA
CTD
PMID:33512557
NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
G
Isl1
ISL LIM homeobox 1
decreases expression
ISO
thifluzamide results in decreased expression of ISL1 mRNA
CTD
PMID:33512557
NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584
G
Itpr1
inositol 1,4,5-trisphosphate receptor, type 1
increases expression
ISO
thifluzamide results in increased expression of ITPR1 mRNA
CTD
PMID:33512557
NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
G
Itpr2
inositol 1,4,5-trisphosphate receptor, type 2
decreases expression
ISO
thifluzamide results in decreased expression of ITPR2 mRNA
CTD
PMID:33512557
NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164
G
Jmjd6
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
increases expression
ISO
thifluzamide results in increased expression of JMJD6 mRNA
CTD
PMID:33512557
NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182
G
Kars1
lysyl-tRNA synthetase 1
decreases expression
ISO
thifluzamide results in decreased expression of KARS1 mRNA
CTD
PMID:33512557
NCBI chr19:39,957,846...39,976,837
Ensembl chr19:39,957,846...39,977,632
G
Kcnq2
potassium voltage-gated channel subfamily Q member 2
decreases expression
ISO
thifluzamide results in decreased expression of KCNQ2 mRNA
CTD
PMID:33512557
NCBI chr 3:168,194,776...168,253,831
Ensembl chr 3:168,195,357...168,275,071
G
Kdelr2
KDEL endoplasmic reticulum protein retention receptor 2
increases expression
ISO
thifluzamide results in increased expression of KDELR2 mRNA
CTD
PMID:33512557
NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153
G
Kif13a
kinesin family member 13A
decreases expression
ISO
thifluzamide results in decreased expression of KIF13A mRNA
CTD
PMID:33512557
NCBI chr17:17,766,597...17,948,517
Ensembl chr17:17,766,597...17,943,615
G
Kif20a
kinesin family member 20A
increases expression
ISO
thifluzamide results in increased expression of KIF20A mRNA
CTD
PMID:33512557
NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
G
Klhl24
kelch-like family member 24
decreases expression
ISO
thifluzamide results in decreased expression of KLHL24 mRNA
CTD
PMID:33512557
NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636
G
L1cam
L1 cell adhesion molecule
decreases expression
ISO
thifluzamide results in decreased expression of L1CAM mRNA
CTD
PMID:33512557
NCBI chr X:151,597,270...151,623,776
Ensembl chr X:151,597,277...151,623,857
G
Lamp3
lysosomal-associated membrane protein 3
increases expression
ISO
thifluzamide results in increased expression of LAMP3 mRNA
CTD
PMID:33512557
NCBI chr11:81,153,491...81,224,643
Ensembl chr11:81,193,649...81,221,784
G
Lmod1
leiomodin 1
decreases expression
ISO
thifluzamide results in decreased expression of LMOD1 mRNA
CTD
PMID:33512557
NCBI chr13:46,754,048...46,796,186
Ensembl chr13:46,754,033...46,794,900
G
LOC102549061
histone H2B type 1-N-like
increases expression
ISO
thifluzamide results in increased expression of H2BC3 mRNA
CTD
PMID:33512557
NCBI chr17:41,380,056...41,380,686
G
Loxl1
lysyl oxidase-like 1
decreases expression
ISO
thifluzamide results in decreased expression of LOXL1 mRNA
CTD
PMID:33512557
NCBI chr 8:58,691,763...58,716,365
Ensembl chr 8:58,692,593...58,716,356
G
Lpcat1
lysophosphatidylcholine acyltransferase 1
decreases expression
ISO
thifluzamide results in decreased expression of LPCAT1 mRNA
CTD
PMID:33512557
NCBI chr 1:29,766,070...29,816,401
Ensembl chr 1:29,766,071...29,816,401
G
Map1lc3b
microtubule-associated protein 1 light chain 3 beta
increases expression
ISO
thifluzamide results in increased expression of MAP1LC3B mRNA
CTD
PMID:33512557
NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
G
Map2
microtubule-associated protein 2
decreases expression
ISO
thifluzamide results in decreased expression of MAP2 mRNA
CTD
PMID:33512557
NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
G
Map6
microtubule-associated protein 6
decreases expression
ISO
thifluzamide results in decreased expression of MAP6 mRNA
CTD
PMID:33512557
NCBI chr 1:153,568,020...153,634,415
Ensembl chr 1:153,568,368...153,634,414
G
Mdk
midkine
increases expression
ISO
thifluzamide results in increased expression of MDK mRNA
CTD
PMID:33512557
NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130
G
Me1
malic enzyme 1
increases expression
ISO
thifluzamide results in increased expression of ME1 mRNA
CTD
PMID:33512557
NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
G
Metrn
meteorin, glial cell differentiation regulator
decreases expression
ISO
thifluzamide results in decreased expression of METRN mRNA
CTD
PMID:33512557
NCBI chr10:14,816,684...14,818,702
Ensembl chr10:14,816,572...14,818,701
G
Mok
MOK protein kinase
increases expression
ISO
thifluzamide results in increased expression of MOK mRNA
CTD
PMID:33512557
NCBI chr 6:129,823,794...129,854,669
Ensembl chr 6:129,823,795...129,854,700
G
Msi2
musashi RNA-binding protein 2
decreases expression
ISO
thifluzamide results in decreased expression of MSI2 mRNA
CTD
PMID:33512557
NCBI chr10:73,143,760...73,510,566
Ensembl chr10:73,147,380...73,510,157
G
Mt-nd6
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6
decreases expression
ISO
thifluzamide results in decreased expression of ND6 mRNA
CTD
PMID:33512557
NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
G
Mt2A
metallothionein 2A
increases expression
ISO
thifluzamide results in increased expression of MT2A mRNA
CTD
PMID:33512557
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
G
Mthfd2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
increases expression
ISO
thifluzamide results in increased expression of MTHFD2 mRNA
CTD
PMID:33512557
NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
G
Myb
MYB proto-oncogene, transcription factor
decreases expression
ISO
thifluzamide results in decreased expression of MYB mRNA
CTD
PMID:33512557
NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
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Myc
MYC proto-oncogene, bHLH transcription factor
increases expression
ISO
thifluzamide results in increased expression of MYC mRNA
CTD
PMID:33512557
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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Myl4
myosin, light chain 4
decreases expression
ISO
thifluzamide results in decreased expression of MYL4 mRNA
CTD
PMID:33512557
NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363
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Nav1
neuron navigator 1
decreases expression
ISO
thifluzamide results in decreased expression of NAV1 mRNA
CTD
PMID:33512557
NCBI chr13:46,866,972...47,119,368
Ensembl chr13:46,873,689...47,126,449
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Ncan
neurocan
decreases expression
ISO
thifluzamide results in decreased expression of NCAN mRNA
CTD
PMID:33512557
NCBI chr16:19,301,969...19,328,436
Ensembl chr16:19,301,969...19,328,436
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Nefl
neurofilament light chain
decreases expression
ISO
thifluzamide results in decreased expression of NEFL mRNA
CTD
PMID:33512557
NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
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Nek2
NIMA-related kinase 2
increases expression
ISO
thifluzamide results in increased expression of NEK2 mRNA
CTD
PMID:33512557
NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
ISO
thifluzamide results in increased expression of NQO1 mRNA
CTD
PMID:33512557
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nr2f1
nuclear receptor subfamily 2, group F, member 1
decreases expression
ISO
thifluzamide results in decreased expression of NR2F1 mRNA
CTD
PMID:33512557
NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123
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Nr3c1
nuclear receptor subfamily 3, group C, member 1
increases expression
ISO
thifluzamide results in increased expression of NR3C1 mRNA
CTD
PMID:33512557
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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Nr4a2
nuclear receptor subfamily 4, group A, member 2
decreases expression
ISO
thifluzamide results in decreased expression of NR4A2 mRNA
CTD
PMID:33512557
NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
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Nrcam
neuronal cell adhesion molecule
decreases expression
ISO
thifluzamide results in decreased expression of NRCAM mRNA
CTD
PMID:33512557
NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
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Nrxn1
neurexin 1
decreases expression
ISO
thifluzamide results in decreased expression of NRXN1 mRNA
CTD
PMID:33512557
NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710
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Olfml2b
olfactomedin-like 2B
decreases expression
ISO
thifluzamide results in decreased expression of OLFML2B mRNA
CTD
PMID:33512557
NCBI chr13:82,869,414...82,906,607
Ensembl chr13:82,869,433...82,906,607
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Ormdl3
ORMDL sphingolipid biosynthesis regulator 3
decreases expression
ISO
thifluzamide results in decreased expression of ORMDL3 mRNA
CTD
PMID:33512557
NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620
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P4ha2
prolyl 4-hydroxylase subunit alpha 2
increases expression
ISO
thifluzamide results in increased expression of P4HA2 mRNA
CTD
PMID:33512557
NCBI chr10:38,243,136...38,271,983
Ensembl chr10:38,243,139...38,287,314
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Pcdh8
protocadherin 8
increases expression
ISO
thifluzamide results in increased expression of PCDH8 mRNA
CTD
PMID:33512557
NCBI chr15:55,198,470...55,203,039
Ensembl chr15:55,198,459...55,205,872
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Pdgfb
platelet derived growth factor subunit B
decreases expression
ISO
thifluzamide results in decreased expression of PDGFB mRNA
CTD
PMID:33512557
NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
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Pebp1
phosphatidylethanolamine binding protein 1
decreases expression
ISO
thifluzamide results in decreased expression of PEBP1 mRNA
CTD
PMID:33512557
NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
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Peg10
paternally expressed 10
decreases expression
ISO
thifluzamide results in decreased expression of PEG10 mRNA
CTD
PMID:33512557
NCBI chr 4:32,842,441...32,855,639
Ensembl chr 4:32,848,493...32,852,621
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Pga5
pepsinogen A5
increases expression
ISO
thifluzamide results in increased expression of PGA5 mRNA
CTD
PMID:33512557
NCBI chr 1:207,317,021...207,327,156
Ensembl chr 1:207,317,021...207,327,156
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Phgdh
phosphoglycerate dehydrogenase
increases expression
ISO
thifluzamide results in increased expression of PHGDH mRNA
CTD
PMID:33512557
NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
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Phlda1
pleckstrin homology-like domain, family A, member 1
decreases expression
ISO
thifluzamide results in decreased expression of PHLDA1 mRNA
CTD
PMID:33512557
NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861
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Pink1
PTEN induced kinase 1
decreases expression
ISO
thifluzamide results in decreased expression of PINK1 mRNA
CTD
PMID:33512557
NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
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Plcb3
phospholipase C beta 3
decreases expression
ISO
thifluzamide results in decreased expression of PLCB3 mRNA
CTD
PMID:33512557
NCBI chr 1:204,143,257...204,160,384
Ensembl chr 1:204,144,956...204,160,228
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Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
increases expression
ISO
thifluzamide results in increased expression of PMAIP1 mRNA
CTD
PMID:33512557
NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
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Pou4f2
POU class 4 homeobox 2
decreases expression
ISO
thifluzamide results in decreased expression of POU4F2 mRNA
CTD
PMID:33512557
NCBI chr19:29,486,686...29,490,327
Ensembl chr19:29,486,686...29,490,327
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Ppp1r17
protein phosphatase 1, regulatory subunit 17
decreases expression
ISO
thifluzamide results in decreased expression of PPP1R17 mRNA
CTD
PMID:33512557
NCBI chr 4:85,213,595...85,230,607
Ensembl chr 4:85,213,887...85,230,603
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Prr11
proline rich 11
increases expression
ISO
thifluzamide results in increased expression of PRR11 mRNA
CTD
PMID:33512557
NCBI chr10:71,898,858...71,943,325
Ensembl chr10:71,901,202...71,921,012
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Psat1
phosphoserine aminotransferase 1
increases expression
ISO
thifluzamide results in increased expression of PSAT1 mRNA
CTD
PMID:33512557
NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
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Ptprf
protein tyrosine phosphatase, receptor type, F
decreases expression
ISO
thifluzamide results in decreased expression of PTPRF mRNA
CTD
PMID:33512557
NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
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Rab31
RAB31, member RAS oncogene family
decreases expression
ISO
thifluzamide results in decreased expression of RAB31 mRNA
CTD
PMID:33512557
NCBI chr 9:105,246,712...105,382,973
Ensembl chr 9:105,246,709...105,381,253
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Rbx1
ring-box 1
decreases expression
ISO
thifluzamide results in decreased expression of RBX1 mRNA
CTD
PMID:33512557
NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051
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Reln
reelin
decreases expression
ISO
thifluzamide results in decreased expression of RELN mRNA
CTD
PMID:33512557
NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211
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Rpl28
ribosomal protein L28
increases expression
ISO
thifluzamide results in increased expression of RPL28 mRNA
CTD
PMID:33512557
NCBI chr 1:69,052,148...69,054,735
Ensembl chr 1:69,053,203...69,055,032
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Rpsa
ribosomal protein SA
increases expression
ISO
thifluzamide results in increased expression of RPSA mRNA
CTD
PMID:33512557
NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247
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Rsl24d1
ribosomal L24 domain containing 1
increases expression
ISO
thifluzamide results in increased expression of RSL24D1 mRNA
CTD
PMID:33512557
NCBI chr 8:73,852,991...73,861,996
Ensembl chr 8:73,852,996...73,862,001
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Rxylt1
ribitol xylosyltransferase 1
increases expression
ISO
thifluzamide results in increased expression of RXYLT1 mRNA
CTD
PMID:33512557
NCBI chr 7:57,770,841...57,782,695
Ensembl chr 7:57,770,842...57,782,657
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Satb1
SATB homeobox 1
decreases expression
ISO
thifluzamide results in decreased expression of SATB1 mRNA
CTD
PMID:33512557
NCBI chr 9:4,677,817...4,773,061
Ensembl chr 9:4,680,920...4,753,251
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Sel1l
SEL1L adaptor subunit of SYVN1 ubiquitin ligase
increases expression
ISO
thifluzamide results in increased expression of SEL1L mRNA
CTD
PMID:33512557
NCBI chr 6:110,735,450...110,779,695
Ensembl chr 6:110,735,450...110,779,648
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Sema6a
semaphorin 6A
decreases expression
ISO
thifluzamide results in decreased expression of SEMA6A mRNA
CTD
PMID:33512557
NCBI chr18:40,050,623...40,171,954
Ensembl chr18:40,050,624...40,171,954
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Sephs2
selenophosphate synthetase 2
increases expression
ISO
thifluzamide results in increased expression of SEPHS2 mRNA
CTD
PMID:33512557
NCBI chr 1:181,893,146...181,895,464
Ensembl chr 1:181,892,599...181,895,497
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Serpine2
serpin family E member 2
increases expression
ISO
thifluzamide results in increased expression of SERPINE2 mRNA
CTD
PMID:33512557
NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
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Sesn2
sestrin 2
increases expression
ISO
thifluzamide results in increased expression of SESN2 mRNA
CTD
PMID:33512557
NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
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Sgcb
sarcoglycan, beta
decreases expression
ISO
thifluzamide results in decreased expression of SGCB mRNA
CTD
PMID:33512557
NCBI chr14:34,563,614...34,578,614
Ensembl chr14:34,563,608...34,578,583
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Slc17a6
solute carrier family 17 member 6
decreases expression
ISO
thifluzamide results in decreased expression of SLC17A6 mRNA
CTD
PMID:33512557
NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542
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Slc1a2
solute carrier family 1 member 2
decreases expression
ISO
thifluzamide results in decreased expression of SLC1A2 mRNA
CTD
PMID:33512557
NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498
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Slc1a4
solute carrier family 1 member 4
increases expression
ISO
thifluzamide results in increased expression of SLC1A4 mRNA
CTD
PMID:33512557
NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418
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Slc2a6
solute carrier family 2 member 6
decreases expression
ISO
thifluzamide results in decreased expression of SLC2A6 mRNA
CTD
PMID:33512557
NCBI chr 3:10,348,395...10,355,208
Ensembl chr 3:10,348,395...10,355,208
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Slc38a1
solute carrier family 38, member 1
increases expression
ISO
thifluzamide results in increased expression of SLC38A1 mRNA
CTD
PMID:33512557
NCBI chr 7:127,733,230...127,802,541
Ensembl chr 7:127,738,226...127,802,218
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Slc3a2
solute carrier family 3 member 2
increases expression
ISO
thifluzamide results in increased expression of SLC3A2 mRNA
CTD
PMID:33512557
NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
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Slc6a3
solute carrier family 6 member 3
decreases expression
ISO
thifluzamide results in decreased expression of SLC6A3 mRNA
CTD
PMID:33512557
NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
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Slc7a5
solute carrier family 7 member 5
increases expression
ISO
thifluzamide results in increased expression of SLC7A5 mRNA
CTD
PMID:33512557
NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
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Slit2
slit guidance ligand 2
decreases expression
ISO
thifluzamide results in decreased expression of SLIT2 mRNA
CTD
PMID:33512557
NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948
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Snai2
snail family transcriptional repressor 2
increases expression
ISO
thifluzamide results in increased expression of SNAI2 mRNA
CTD
PMID:33512557
NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200
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Spag5
sperm associated antigen 5
increases expression
ISO
thifluzamide results in increased expression of SPAG5 mRNA
CTD
PMID:33512557
NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,198,768...63,216,745
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Spc25
SPC25 component of NDC80 kinetochore complex
increases expression
ISO
thifluzamide results in increased expression of SPC25 mRNA
CTD
PMID:33512557
NCBI chr 3:53,930,013...53,988,940
Ensembl chr 3:53,975,704...53,988,959
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Spdef
SAM pointed domain containing ets transcription factor
decreases expression
ISO
thifluzamide results in decreased expression of SPDEF mRNA
CTD
PMID:33512557
NCBI chr20:5,771,440...5,785,893
Ensembl chr20:5,771,441...5,785,893
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Spred2
sprouty-related, EVH1 domain containing 2
increases expression
ISO
thifluzamide results in increased expression of SPRED2 mRNA
CTD
PMID:33512557
NCBI chr14:94,149,210...94,250,787
Ensembl chr14:94,148,837...94,249,162
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Srsf10
serine and arginine rich splicing factor 10
increases expression
ISO
thifluzamide results in increased expression of SRSF10 mRNA
CTD
PMID:33512557
NCBI chr 5:148,088,759...148,102,964
Ensembl chr 5:148,088,823...148,101,768
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Sst
somatostatin
decreases expression
ISO
thifluzamide results in decreased expression of SST mRNA
CTD
PMID:33512557
NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173
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Sytl1
synaptotagmin-like 1
increases expression
ISO
thifluzamide results in increased expression of SYTL1 mRNA
CTD
PMID:33512557
NCBI chr 5:145,452,524...145,462,940
Ensembl chr 5:145,422,669...145,462,940
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Taf9
TATA-box binding protein associated factor 9
increases expression
ISO
thifluzamide results in increased expression of TAF9 mRNA
CTD
PMID:33512557
NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769
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Tcf4
transcription factor 4
decreases expression
ISO
thifluzamide results in decreased expression of TCF4 mRNA
CTD
PMID:33512557
NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425
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Tfdp1
transcription factor Dp-1
decreases expression
ISO
thifluzamide results in decreased expression of TFDP1 mRNA
CTD
PMID:33512557
NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817
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Tgfb3
transforming growth factor, beta 3
decreases expression
ISO
thifluzamide results in decreased expression of TGFB3 mRNA
CTD
PMID:33512557
NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
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Tmem97
transmembrane protein 97
decreases expression
ISO
thifluzamide results in decreased expression of TMEM97 mRNA
CTD
PMID:33512557
NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730
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Tnc
tenascin C
decreases expression
ISO
thifluzamide results in decreased expression of TNC mRNA
CTD
PMID:33512557
NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
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Top2a
DNA topoisomerase II alpha
increases expression
ISO
thifluzamide results in increased expression of TOP2A mRNA
CTD
PMID:33512557
NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
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Tpi1
triosephosphate isomerase 1
decreases expression
ISO
thifluzamide results in decreased expression of TPI1 mRNA
CTD
PMID:33512557
NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
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Tpx2
TPX2, microtubule nucleation factor
increases expression
ISO
thifluzamide results in increased expression of TPX2 mRNA
CTD
PMID:33512557
NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468
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Trib3
tribbles pseudokinase 3
increases expression
ISO
thifluzamide results in increased expression of TRIB3 mRNA
CTD
PMID:33512557
NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
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Trim13
tripartite motif-containing 13
decreases expression
ISO
thifluzamide results in decreased expression of TRIM13 mRNA
CTD
PMID:33512557
NCBI chr15:35,733,548...35,772,676
Ensembl chr15:35,734,107...35,772,677
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Tsc22d3
TSC22 domain family, member 3
increases expression
ISO
thifluzamide results in increased expression of TSC22D3 mRNA
CTD
PMID:33512557
NCBI chr X:104,217,898...104,277,886
Ensembl chr X:104,217,925...104,276,861
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Ttk
Ttk protein kinase
increases expression
ISO
thifluzamide results in increased expression of TTK mRNA
CTD
PMID:33512557
NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
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Tubb2a
tubulin, beta 2A class IIa
decreases expression
ISO
thifluzamide results in decreased expression of TUBB2A mRNA
CTD
PMID:33512557
NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
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Tubb2b
tubulin, beta 2B class IIb
decreases expression
ISO
thifluzamide results in decreased expression of TUBB2B mRNA
CTD
PMID:33512557
NCBI chr17:30,747,734...30,750,781
Ensembl chr17:30,747,734...30,750,638
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Tubb3
tubulin, beta 3 class III
decreases expression
ISO
thifluzamide results in decreased expression of TUBB3 mRNA
CTD
PMID:33512557
NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
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Tut7
terminal uridylyl transferase 7
decreases expression
ISO
thifluzamide results in decreased expression of TUT7 mRNA
CTD
PMID:33512557
NCBI chr17:4,849,287...4,903,542
Ensembl chr17:4,849,283...4,903,169
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Txndc5
thioredoxin domain containing 5
increases expression
ISO
thifluzamide results in increased expression of TXNDC5 mRNA
CTD
PMID:33512557
NCBI chr17:26,289,880...26,318,025
Ensembl chr17:26,289,880...26,318,025
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Txnip
thioredoxin interacting protein
decreases expression
ISO
thifluzamide results in decreased expression of TXNIP mRNA
CTD
PMID:33512557
NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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Txnrd1
thioredoxin reductase 1
increases expression
ISO
thifluzamide results in increased expression of TXNRD1 mRNA
CTD
PMID:33512557
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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Txnrd2
thioredoxin reductase 2
increases expression
ISO
thifluzamide results in increased expression of TXNRD2 mRNA
CTD
PMID:33512557
NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
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Ubb
ubiquitin B
increases expression
ISO
thifluzamide results in increased expression of UBB mRNA
CTD
PMID:33512557
NCBI chr10:47,247,630...47,249,335
Ensembl chr10:47,245,637...47,249,333
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Ube2c
ubiquitin-conjugating enzyme E2C
increases expression
ISO
thifluzamide results in increased expression of UBE2C mRNA
CTD
PMID:33512557
NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
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Uhrf1
ubiquitin-like with PHD and ring finger domains 1
decreases expression
ISO
thifluzamide results in decreased expression of UHRF1 mRNA
CTD
PMID:33512557
NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631
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Vegfa
vascular endothelial growth factor A
increases expression
ISO
thifluzamide results in increased expression of VEGFA mRNA
CTD
PMID:33512557
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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Vegfd
vascular endothelial growth factor D
decreases expression
ISO
thifluzamide results in decreased expression of VEGFD mRNA
CTD
PMID:33512557
NCBI chr X:30,073,122...30,108,413
Ensembl chr X:30,074,163...30,108,295
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Vim
vimentin
increases expression
ISO
thifluzamide results in increased expression of VIM mRNA
CTD
PMID:33512557
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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Wars1
tryptophanyl-tRNA synthetase 1
increases expression
ISO
thifluzamide results in increased expression of WARS1 mRNA
CTD
PMID:33512557
NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269
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Wdtc1
WD and tetratricopeptide repeats 1
decreases expression
ISO
thifluzamide results in decreased expression of WDTC1 mRNA
CTD
PMID:33512557
NCBI chr 5:145,491,460...145,559,631
Ensembl chr 5:145,491,466...145,540,408
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Xbp1
X-box binding protein 1
increases expression
ISO
thifluzamide results in increased expression of XBP1 mRNA
CTD
PMID:33512557
NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
G
Zeb2
zinc finger E-box binding homeobox 2
decreases expression
ISO
thifluzamide results in decreased expression of ZEB2 mRNA
CTD
PMID:33512557
NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
CHEBI ontology
19834
chemical entity
19832
molecular entity
19832
polyatomic entity
19790
heteroatomic molecular entity
19746
halide
18658
organohalogen compound
18531
organobromine compound
6582
bromobenzenes
4047
dibromobenzene
591
(Z)-3',5'-dibromo-2',4,4',6'-tetrahydroxyaurone
0
1,2-dibromobenzene
0
1,3-dibromobenzene +
351
1,4-dibromobenzene
1
2,4-dibromophenol
14
3,5-dibromo-4-hydroxybenzamide
0
3,5-dibromo-4-hydroxybenzoic acid
0
3,5-dibromo-4-hydroxybenzonitrile
2
3,5-dibromocatechol
0
LFM-A13
0
dibromophenol +
351
phloxine O
1
thifluzamide
242
Path 2
CHEBI ontology
19834
subatomic particle
19832
composite particle
19832
hadron
19832
baryon
19832
nucleon
19832
atomic nucleus
19832
atom
19832
main group element atom
19782
p-block element atom
19782
carbon group element atom
19731
carbon group molecular entity
19731
organic molecular entity
19727
organic molecule
19680
organic cyclic compound
19493
organic aromatic compound
19360
benzenoid aromatic compound
18004
benzenes
17867
bromobenzenes
4047
dibromobenzene
591
(Z)-3',5'-dibromo-2',4,4',6'-tetrahydroxyaurone
0
1,2-dibromobenzene
0
1,3-dibromobenzene +
351
1,4-dibromobenzene
1
2,4-dibromophenol
14
3,5-dibromo-4-hydroxybenzamide
0
3,5-dibromo-4-hydroxybenzoic acid
0
3,5-dibromo-4-hydroxybenzonitrile
2
3,5-dibromocatechol
0
LFM-A13
0
dibromophenol +
351
phloxine O
1
thifluzamide
242