Gene: Itpr1 (inositol 1,4,5-trisphosphate receptor, type 1)  Rattus norvegicus

Symbol: Itpr1
Name: inositol 1,4,5-trisphosphate receptor, type 1
Description: ENCODES a protein that exhibits inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; protein C-terminus binding; protein complex binding; INVOLVED IN cellular response to cAMP; cellular response to hypoxia; elevation of cytosolic calcium ion concentration; PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; Alzheimer disease pathway; ASSOCIATED WITH Asthma; Heart Arrest; Huntington Disease; FOUND IN cytoplasm; dendrite; endoplasmic reticulum membrane; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: I145TR; inositol 1,4,5-triphosphate receptor 1; inositol 1,4,5-triphosphate receptor type 1; inositol 1,4,5-triphosphate receptor, type 1; inositol 1,4,5-trisphosphate receptor type 1; inositol 1,4,5-trisphosphate receptor, type 1; inositol 145-triphosphate receptor type 1; InsP3R; InsP3R1; IP-3-R; IP3 receptor; IP3R 1; type 1 inositol 1,4,5-trisphosphate receptor; type 1 InsP3 receptor
Orthologs: Homo sapiens : ITPR1 (inositol 1,4,5-trisphosphate receptor, type 1)  HGNC
Mus musculus : Itpr1 (inositol 1,4,5-trisphosphate receptor 1)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map4q41 NCBI
RGSC Genome Assembly v5.04204,714,826 - 205,047,900+NCBI
RGSC Genome Assembly v3.44143,705,360 - 144,030,051+NCBI
Rat Celera Assembly4129,839,611 - 130,162,656+NCBI
Genome Assembly 3.14143,950,200 - 144,274,892+NCBI
RH 3.44890.9 RGD
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Itpr1
Entrez Gene
Ensembl Gene
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RGD Object Information
RGD ID: 2933
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE