Gene: Itpr1 (inositol 1,4,5-trisphosphate receptor, type 1) Rattus norvegicus
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Symbol: Itpr1
Name: inositol 1,4,5-trisphosphate receptor, type 1
Description: ENCODES a protein that exhibits identical protein binding; inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; protein C-terminus binding; INVOLVED IN cellular response to cAMP; cellular response to hypoxia; negative regulation of neuron death; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH Asthma; asthma; cardiac arrest; FOUND IN cytoplasm; dendrite; endoplasmic reticulum membrane; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE; 17alpha-ethynylestradiol
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: I145TR; inositol 1,4,5-triphosphate receptor 1; inositol 1,4,5-triphosphate receptor type 1; inositol 1,4,5-triphosphate receptor, type 1; inositol 1,4,5-trisphosphate receptor type 1; inositol 145-triphosphate receptor type 1; InsP3R; InsP3R1; IP-3-R; IP3 receptor; IP3R 1; IP3R1; P400; type 1 inositol 1,4,5-trisphosphate receptor; type 1 InsP3 receptor
Orthologs:
Homo sapiens (human) : ITPR1 (inositol 1,4,5-trisphosphate receptor type 1)  HGNC  AGR
Mus musculus (house mouse) : Itpr1 (inositol 1,4,5-trisphosphate receptor 1)  MGI  AGR
Pan paniscus (bonobo/pygmy chimpanzee) : ITPR1 (inositol 1,4,5-trisphosphate receptor type 1)
Canis lupus familiaris (dog) : ITPR1 (inositol 1,4,5-trisphosphate receptor type 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itpr1 (inositol 1,4,5-trisphosphate receptor type 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04140,247,297 - 140,580,749 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04204,714,729 - 205,047,901 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44143,705,360 - 144,030,051NCBIRGSC3.4rn4RGSC3.4
Celera4129,839,611 - 130,162,657 (+)NCBICelera
Cytogenetic Map4q41NCBI
RH 3.4 Map4 RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants