Gene: Plcb3 (phospholipase C beta 3) Rattus norvegicus
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Symbol: Plcb3
Name: phospholipase C beta 3
Description: ENCODES a protein that exhibits phosphatidylinositol phospholipase C activity; calmodulin binding (ortholog); INVOLVED IN G-protein coupled receptor signaling pathway; inositol trisphosphate metabolic process; phosphatidylinositol catabolic process; PARTICIPATES IN endothelin signaling pathway; G protein mediated signaling pathway via Galphaq family; protein kinase C (PKC) signaling pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental; Myocardial Infarction; Skin Ulcer (ortholog); FOUND IN cytosol; sarcolemma; nucleoplasm (ortholog); INTERACTS WITH (R)-noradrenaline; 2,3,7,8-tetrachlorodibenzodioxine; 2-ethoxyethanol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3; phosphoinositide phospholipase C-beta-3; phospholipase C, beta 3 (phosphatidylinositol-specific); phospholipase C-beta-3; PLC-beta-3
Orthologs:
Allele / Splice: Plcb3Tn(sb-T2/Bart3)2.69Mcwi  
Genetic Models: F344-Plcb3Tn(sb-T2/Bart3)2.69Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01222,207,887 - 222,224,993 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01229,198,739 - 229,215,831 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41209,628,425 - 209,643,694 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11209,786,729 - 209,802,063 (-)NCBI
Celera1201,678,898 - 201,694,162 (-)NCBI
Cytogenetic Map1q43NCBImapview
RH 3.4 Map11521.0RGD
Model


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References - uncurated
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Genomics

Comparative Map Data
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QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Plcb3
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 61993
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2016-11-22
Status: ACTIVE