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ONTOLOGY REPORT - ANNOTATIONS


Term:lytic vacuole organization
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Accession:GO:0080171 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole.
Synonyms:exact_synonym: lytic vacuole organisation
 narrow_synonym: lytic vacuolar assembly
 related_synonym: lytic vacuole biogenesis;   lytic vacuole organization and biogenesis



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lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 involved_in ISO
IEA
ISS
(PMID:32276428)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:32276428 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918
JBrowse link
G Ccdc115 coiled-coil domain containing 115 involved_in ISO (PMID:28296633) RGD PMID:28296633 NCBI chr 9:36,650,384...36,654,348
Ensembl chr 9:36,649,271...36,653,946
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO
IBA
(PMID:11722572)
GO_REF:0000033
RGD
GO_Central
PMID:11722572 GO_REF:0000033 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
JBrowse link
G Cln5 CLN5, intracellular trafficking protein involved_in ISO (PMID:11722572) RGD PMID:11722572 NCBI chr15:79,893,573...79,903,438
Ensembl chr15:79,893,548...79,903,438
JBrowse link
G Cln6 CLN6, transmembrane ER protein involved_in ISO (PMID:11722572) RGD PMID:11722572 NCBI chr 8:63,303,356...63,318,360
Ensembl chr 8:63,303,029...63,318,360
JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 acts_upstream_of_or_within ISO (MGI:6854654|PMID:33966596) RGD PMID:33966596 MGI:6854654 NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308
JBrowse link
G Grn granulin precursor involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:28073925)
UniProt
Ensembl
RGD
PMID:28073925 GO_REF:0000024 GO_REF:0000107 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:37390818)
Ensembl
UniProt
RGD
PMID:37390818 GO_REF:0000024 GO_REF:0000107 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:37390818)
Ensembl
UniProt
RGD
PMID:37390818 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in ISO
ISS
(PMID:11722572)
PMID:8895569
RGD PMID:11722572 PMID:8895569 RGD:8553248 NCBI chr 5:135,121,164...135,142,048
Ensembl chr 5:135,121,163...135,142,048
JBrowse link
G Snapin SNAP-associated protein acts_upstream_of_or_within ISO MGI:3608768 (MGI:4879078|PMID:20920792) RGD PMID:20920792 MGI:4879078 NCBI chr 2:175,971,575...175,974,164
Ensembl chr 2:175,971,257...175,974,231
JBrowse link
G Tmem106b transmembrane protein 106B acts_upstream_of_or_within ISO MGI:5319917 (MGI:6101836|PMID:28728022) RGD PMID:28728022 MGI:6101836 NCBI chr 4:41,328,125...41,347,315
Ensembl chr 4:41,327,994...41,345,619
JBrowse link
G Tmem199 transmembrane protein 199 involved_in ISO
IEA
ISS
(PMID:28296633)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:28296633 GO_REF:0000024 GO_REF:0000107 NCBI chr10:63,402,493...63,407,065
Ensembl chr10:63,402,494...63,407,108
JBrowse link
G Tmem9 transmembrane protein 9 involved_in ISO (PMID:30374053) RGD PMID:30374053 NCBI chr13:47,458,486...47,475,832
Ensembl chr13:47,458,498...47,475,832
JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:10924275) RGD PMID:10924275 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein involved_in ISO (PMID:25513726), (PMID:32966160) RGD PMID:25513726 PMID:32966160 NCBI chr 1:107,116,278...107,446,093
Ensembl chr 1:107,116,278...107,446,074
JBrowse link
G Slc45a2 solute carrier family 45, member 2 involved_in ISO (PMID:32966160)
(MGI:7338895|PMID:35469906)
RGD PMID:32966160 PMID:35469906 MGI:7338895 NCBI chr 2:59,963,599...59,996,408
Ensembl chr 2:59,963,706...59,996,317
JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISS
ISO
GO_REF:0000024
(PMID:35333573), (PMID:35750034), (PMID:37390818)
UniProt
RGD
PMID:35333573 PMID:35750034 PMID:37390818 GO_REF:0000024 NCBI chr14:1,073,410...1,089,764
Ensembl chr14:1,073,523...1,089,819
JBrowse link
lysosomal membrane organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf1 ADP-ribosylation factor 1 IDA RGD PMID:9538255 RGD:9684948 NCBI chr10:43,997,983...44,014,461
Ensembl chr10:43,997,986...44,014,434
JBrowse link
G Atp10b ATPase phospholipid transporting 10B involved_in ISO (PMID:32172343) RGD PMID:32172343 NCBI chr10:27,495,207...27,751,313
Ensembl chr10:27,408,747...27,749,637
JBrowse link
lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 involved_in ISO (PMID:15163665) RGD PMID:15163665 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Acp2 acid phosphatase 2, lysosomal acts_upstream_of_or_within
involved_in
ISO
IEA
IBA
MGI:2180084|MGI:3574793 (MGI:3522374|PMID:15604265), (MGI:894905|PMID:9228031)
GO_REF:0000118
GO_REF:0000033
RGD
TreeGrafter
GO_Central
PMID:9228031 PMID:15604265 GO_REF:0000033 GO_REF:0000118 MGI:3522374 MGI:894905 NCBI chr 3:77,175,022...77,185,180
Ensembl chr 3:77,175,895...77,185,680
JBrowse link
G Acp3 acid phosphatase 3 involved_in IEA
IBA
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr 8:104,905,570...104,956,146
Ensembl chr 8:104,905,586...104,954,236
JBrowse link
G Acp4 acid phosphatase 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:94,736,376...94,751,871
Ensembl chr 1:94,735,514...94,744,623
JBrowse link
G Aktip AKT interacting protein involved_in ISO
IEA
ISS
(PMID:18799622)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:18799622 GO_REF:0000024 GO_REF:0000107 NCBI chr19:15,866,811...15,877,123
Ensembl chr19:15,866,928...15,886,663
JBrowse link
G Ap3b1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within ISO (MGI:1330543|PMID:9931340), (MGI:6415001|PMID:30786955) RGD PMID:9931340 PMID:30786955 MGI:1330543 MGI:6415001 NCBI chr 2:25,600,069...25,800,937
Ensembl chr 2:25,600,040...25,800,935
JBrowse link
G Becn1 beclin 1 acts_upstream_of_or_within ISO MGI:2683696 (MGI:3801567|PMID:18497889) RGD PMID:18497889 MGI:3801567 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Chmp5 charged multivesicular body protein 5 acts_upstream_of_or_within ISO MGI:3626293 (MGI:3622513|PMID:16567502) RGD PMID:16567502 MGI:3622513 NCBI chr 5:56,081,385...56,098,529
Ensembl chr 5:56,081,343...56,098,529
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:1933976|MGI:2388887|MGI:3623134 (MGI:1337525|PMID:10191119), (MGI:1343910|PMID:10440905), (MGI:1346962|PMID:10527801), (MGI:3527911|PMID:15588329)
GO_REF:0000033
RGD
GO_Central
PMID:10191119 PMID:10440905 PMID:10527801 PMID:15588329 GO_REF:0000033 MGI:1337525 MGI:1343910 MGI:1346962 MGI:3527911 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
JBrowse link
G Cln5 CLN5, intracellular trafficking protein acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:3521802 (MGI:3512689|PMID:15459177)
GO_REF:0000033
RGD
GO_Central
PMID:15459177 GO_REF:0000033 MGI:3512689 NCBI chr15:79,893,573...79,903,438
Ensembl chr15:79,893,548...79,903,438
JBrowse link
G Cln6 CLN6, transmembrane ER protein acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:2159328 (MGI:1203267|PMID:9600738), (MGI:5751614|PMID:26681805)
GO_REF:0000033
RGD
GO_Central
PMID:9600738 PMID:26681805 GO_REF:0000033 MGI:1203267 MGI:5751614 NCBI chr 8:63,303,356...63,318,360
Ensembl chr 8:63,303,029...63,318,360
JBrowse link
G Cln8 CLN8, transmembrane ER and ERGIC protein acts_upstream_of_or_within ISO MGI:1856959 (MGI:1333651|PMID:10087069), (MGI:65559|PMID:8144516), (MGI:66707|PMID:8160780), (MGI:71226|PMID:7613514) RGD PMID:7613514 PMID:8144516 PMID:8160780 PMID:10087069 MGI:1333651 MGI:65559 MGI:66707 MGI:71226 NCBI chr16:74,749,662...74,759,553
Ensembl chr16:74,749,662...74,759,774
JBrowse link
G Clvs1 clavesin 1 involved_in IMP
IEA
IBA
PMID:19651769
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
PMID:19651769 GO_REF:0000033 GO_REF:0000118, RGD:8553526 NCBI chr 5:22,408,384...22,604,281
Ensembl chr 5:22,408,384...22,604,270
JBrowse link
G Clvs2 clavesin 2 involved_in IMP
IBA
IEA
PMID:19651769
GO_REF:0000033
GO_REF:0000118
GO_Central
TreeGrafter
PMID:19651769 GO_REF:0000033 GO_REF:0000118, RGD:8553526 NCBI chr 1:23,735,660...23,842,685
Ensembl chr 1:23,735,272...23,842,692
JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 acts_upstream_of_or_within ISO (MGI:6854654|PMID:33966596) RGD PMID:33966596 MGI:6854654 NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308
JBrowse link
G Fhip1b FHF complex subunit HOOK interacting protein 1B involved_in ISS
IBA
IEA
ISO
GO_REF:0000024
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
(PMID:18799622)
UniProt
GO_Central
TreeGrafter
Ensembl
RGD
PMID:18799622 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:159,718,679...159,748,449
Ensembl chr 1:159,726,004...159,748,408
JBrowse link
G Gaa alpha glucosidase involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
GO_REF:0000107
GO_REF:0000033
MGI:2148550|MGI:2179961 (MGI:1195358|PMID:9384603), (MGI:1275872|PMID:9668092), (MGI:1346721|PMID:10547605), (MGI:2136118|PMID:11328962), (MGI:3618942|PMID:15169761), (MGI:3664400|PMID:12115977)
(PMID:7717400)
Ensembl
GO_Central
RGD
PMID:7717400 PMID:9384603 PMID:9668092 PMID:10547605 PMID:11328962 More... GO_REF:0000033 GO_REF:0000107 MGI:1195358 MGI:1275872 MGI:1346721 MGI:2136118 MGI:3618942 MGI:3664400 NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836
JBrowse link
G Gba1 glucosylceramidase beta 1 involved_in ISO (PMID:27378698)
(MGI:5817293|PMID:27378698)
RGD PMID:27378698 MGI:5817293 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
JBrowse link
G Gnptab N-acetylglucosamine-1-phosphate transferase subunits alpha and beta involved_in ISO (PMID:21719679) RGD PMID:21719679 NCBI chr 7:22,800,502...22,866,336
Ensembl chr 7:22,800,485...22,866,933
JBrowse link
G Grn granulin precursor involved_in ISO
ISS
(MGI:6274951|PMID:27789271)
GO_REF:0000024
RGD
UniProt
PMID:27789271 GO_REF:0000024 MGI:6274951 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Hexa hexosaminidase subunit alpha acts_upstream_of_or_within ISO MGI:1857181|MGI:2429698|MGI:3581540|MGI:96074 (MGI:1097747|PMID:9302266), (MGI:1271008|PMID:9645704), (MGI:1352198|PMID:10591619), (MGI:3033296|PMID:14972652), (MGI:69059|PMID:7937929), (MGI:77946|PMID:8747922), (MGI:83770|PMID:8896570), (MGI:86923|PMID:9103204), (MGI:894634|PMID:9184660) RGD PMID:7937929 PMID:8747922 PMID:8896570 PMID:9103204 PMID:9184660 More... MGI:1097747 MGI:1271008 MGI:1352198 MGI:3033296 MGI:69059 MGI:77946 MGI:83770 MGI:86923 MGI:894634 NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013
JBrowse link
G Hexb hexosaminidase subunit beta involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2429701|MGI:96073 (MGI:1271008|PMID:9645704), (MGI:78473|PMID:8789434), (MGI:83770|PMID:8896570), (MGI:894634|PMID:9184660)
Ensembl
RGD
PMID:8789434 PMID:8896570 PMID:9184660 PMID:9645704 GO_REF:0000107 MGI:1271008 MGI:78473 MGI:83770 MGI:894634 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Hook1 hook microtubule-tethering protein 1 involved_in ISO (PMID:18799622) RGD PMID:18799622 NCBI chr 5:110,824,501...110,887,791
Ensembl chr 5:110,824,501...110,887,787
JBrowse link
G Hook2 hook microtubule-tethering protein 2 involved_in ISO (PMID:18799622) RGD PMID:18799622 NCBI chr19:23,151,869...23,170,139
Ensembl chr19:23,151,870...23,164,181
JBrowse link
G Hook3 hook microtubule-tethering protein 3 involved_in ISO (PMID:18799622) RGD PMID:18799622 NCBI chr16:65,954,293...66,058,812
Ensembl chr16:65,954,350...66,061,338
JBrowse link
G Hps1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 acts_upstream_of_or_within ISO (MGI:6415001|PMID:30786955) RGD PMID:30786955 MGI:6415001 NCBI chr 1:241,551,180...241,577,292
Ensembl chr 1:241,551,175...241,577,268
JBrowse link
G Hps4 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 involved_in ISO (PMID:12663659) RGD PMID:12663659 NCBI chr12:44,264,037...44,294,791
Ensembl chr12:44,264,037...44,294,632
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 acts_upstream_of_or_within ISO MGI:3799948 (MGI:6110397|PMID:29180785) RGD PMID:29180785 MGI:6110397 NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
JBrowse link
G Idua alpha-L-iduronidase acts_upstream_of_or_within ISO MGI:2176236|MGI:4415188 (MGI:4414887|PMID:19751987), (MGI:86916|PMID:9097952) RGD PMID:9097952 PMID:19751987 MGI:4414887 MGI:86916 NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522
JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000002
(MGI:4887551|PMID:19177150)
UniProt
InterPro
RGD
PMID:19177150 GO_REF:0000002 GO_REF:0000024 MGI:4887551 NCBI chr 1:156,272,116...156,277,687
Ensembl chr 1:156,272,064...156,291,179
JBrowse link
G Lamtor1l1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 like 1 involved_in ISS
IEA
GO_REF:0000024
GO_REF:0000002
UniProt
InterPro
GO_REF:0000002 GO_REF:0000024 NCBI chr  X:34,637,460...34,638,509
Ensembl chr  X:34,637,459...34,638,516
JBrowse link
G Lipa lipase A, lysosomal acid type acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:2451080 (MGI:5752449|PMID:25807535), (MGI:6158177|PMID:29374543)
GO_REF:0000107
RGD
Ensembl
PMID:25807535 PMID:29374543 GO_REF:0000107 MGI:5752449 MGI:6158177 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:25416817) RGD PMID:25416817 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Lyset lysosomal enzyme trafficking factor involved_in ISS
ISO
GO_REF:0000024
(PMID:36096887)
UniProt
RGD
PMID:36096887 GO_REF:0000024 NCBI chr 6:121,884,577...121,886,319
Ensembl chr 6:121,884,643...121,886,275
JBrowse link
G Lyst lysosomal trafficking regulator acts_upstream_of_or_within ISO MGI:1855968|MGI:1855969 (MGI:1099544|PMID:9368050), (MGI:53816|PMID:4697831), (MGI:53992|PMID:1113502), (MGI:55104|PMID:6170520), (MGI:56449|PMID:4031470) RGD PMID:1113502 PMID:4031470 PMID:4697831 PMID:6170520 PMID:9368050 MGI:1099544 MGI:53816 MGI:53992 MGI:55104 MGI:56449 NCBI chr17:86,241,384...86,443,501
Ensembl chr17:86,241,384...86,443,480
JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:21719679)
UniProt
Ensembl
RGD
PMID:21719679 GO_REF:0000024 GO_REF:0000107 NCBI chr19:47,561,598...47,612,769
Ensembl chr19:47,561,598...47,612,791
JBrowse link
G Mfsd8 major facilitator superfamily domain containing 8 acts_upstream_of_or_within ISO MGI:4456699 (MGI:5575728|PMID:24423645), (MGI:5751614|PMID:26681805) RGD PMID:24423645 PMID:26681805 MGI:5575728 MGI:5751614 NCBI chr 2:123,822,042...123,847,808
Ensembl chr 2:123,816,614...123,857,971
JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISO
IEA
ISS
(PMID:22692423)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:22692423 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Myo7a myosin VIIA involved_in ISO (PMID:16001398) RGD PMID:16001398 NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157
JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO MGI:1934018 (MGI:3769195|PMID:17712420), (MGI:4412159|PMID:19632871), (MGI:5621235|PMID:25524704), (MGI:6219748|PMID:26607664) RGD PMID:17712420 PMID:19632871 PMID:25524704 PMID:26607664 MGI:3769195 MGI:4412159 MGI:5621235 MGI:6219748 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972
JBrowse link
G Pi4kb phosphatidylinositol 4-kinase beta involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:25365221)
Ensembl
RGD
PMID:25365221 GO_REF:0000107 NCBI chr 2:182,540,377...182,572,684
Ensembl chr 2:182,540,567...182,588,488
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 acts_upstream_of_or_within ISO MGI:2176390|MGI:3527191 (MGI:3612221|PMID:16368712), (MGI:3654230|PMID:16542649) RGD PMID:16368712 PMID:16542649 MGI:3612221 MGI:3654230 NCBI chr 5:135,121,164...135,142,048
Ensembl chr 5:135,121,163...135,142,048
JBrowse link
G Snapin SNAP-associated protein acts_upstream_of_or_within
involved_in
ISO
IEA
IBA
MGI:3608768 (MGI:4879078|PMID:20920792)
GO_REF:0000118
GO_REF:0000033
RGD
TreeGrafter
GO_Central
PMID:20920792 GO_REF:0000033 GO_REF:0000118 MGI:4879078 NCBI chr 2:175,971,575...175,974,164
Ensembl chr 2:175,971,257...175,974,231
JBrowse link
G Spg11 SPG11 vesicle trafficking associated, spatacsin acts_upstream_of_or_within ISO MGI:4377985|MGI:6451766 (MGI:5749311|PMID:26284655), (MGI:6141536|PMID:28237315), (MGI:6433162|PMID:31637311)
(PMID:25365221)
RGD PMID:25365221 PMID:26284655 PMID:28237315 PMID:31637311 MGI:5749311 MGI:6141536 MGI:6433162 NCBI chr 3:109,007,658...109,072,904
Ensembl chr 3:109,008,135...109,072,911
JBrowse link
G Tfe3 transcription factor binding to IGHM enhancer 3 involved_in ISO (PMID:24448649) RGD PMID:24448649 NCBI chr  X:14,729,547...14,742,830
Ensembl chr  X:14,729,550...14,742,571
JBrowse link
G Tfeb transcription factor EB acts_upstream_of_or_within
involved_in
ISO (MGI:6433162|PMID:31637311)
(PMID:22692423), (PMID:23434374), (PMID:32612235), (PMID:32753672), (PMID:35662396)
RGD PMID:22692423 PMID:23434374 PMID:31637311 PMID:32612235 PMID:32753672 More... MGI:6433162 NCBI chr 9:13,198,890...13,254,726
Ensembl chr 9:13,198,891...13,254,714
JBrowse link
G Tmem106b transmembrane protein 106B acts_upstream_of_or_within
involved_in
ISO
IBA
IEA
(MGI:5588048|PMID:25066864)
GO_REF:0000033
GO_REF:0000118
RGD
GO_Central
TreeGrafter
PMID:25066864 GO_REF:0000033 GO_REF:0000118 MGI:5588048 NCBI chr 4:41,328,125...41,347,315
Ensembl chr 4:41,327,994...41,345,619
JBrowse link
G Tpcn2 two pore segment channel 2 involved_in ISO UniProtKB:Q8NHX9 (PMID:25416817) RGD PMID:25416817 NCBI chr 1:200,416,538...200,446,252
Ensembl chr 1:200,416,540...200,446,236
JBrowse link
G Tpp1 tripeptidyl peptidase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:3521972 (MGI:3522013|PMID:15483130)
GO_REF:0000107
RGD
Ensembl
PMID:15483130 GO_REF:0000107 MGI:3522013 NCBI chr 1:160,097,984...160,104,108
Ensembl chr 1:160,096,833...160,104,129
JBrowse link
G Vps18 VPS18 core subunit of CORVET and HOPS complexes involved_in ISO
IBA
(PMID:18799622)
GO_REF:0000033
RGD
GO_Central
PMID:18799622 GO_REF:0000033 NCBI chr 3:106,279,444...106,290,298
Ensembl chr 3:106,279,425...106,291,964
JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO (MGI:5694519|PMID:26203154) RGD PMID:26203154 MGI:5694519 NCBI chr19:21,765,771...21,801,620
Ensembl chr19:21,765,749...21,801,618
JBrowse link
G Washc5 WASH complex subunit 5 acts_upstream_of_or_within ISO MGI:6246601 (MGI:6199426|PMID:30061306) RGD PMID:30061306 MGI:6199426 NCBI chr 7:90,884,192...90,936,096
Ensembl chr 7:90,884,197...90,936,103
JBrowse link
G Zfyve26 zinc finger FYVE-type containing 26 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:25365221)
GO_REF:0000107
RGD
Ensembl
PMID:25365221 GO_REF:0000107 NCBI chr 6:98,031,874...98,095,538
Ensembl chr 6:98,032,520...98,095,480
JBrowse link
G Zkscan3 zinc finger with KRAB and SCAN domains 3 involved_in ISO (PMID:23434374) RGD PMID:23434374 NCBI chr17:43,217,168...43,232,828
Ensembl chr17:43,217,222...43,232,827
JBrowse link
multivesicular body-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chmp3 charged multivesicular body protein 3 involved_in ISO (PMID:16554368) RGD PMID:16554368 NCBI chr 4:103,576,453...103,622,566
Ensembl chr 4:103,576,515...103,623,959
JBrowse link
negative regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1 IMP RGD PMID:25561470 RGD:11561937 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Flcn folliculin involved_in ISO (PMID:37079666) RGD PMID:37079666 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Fnip1 folliculin interacting protein 1 involved_in ISO (PMID:37079666) RGD PMID:37079666 NCBI chr10:38,567,728...38,650,824
Ensembl chr10:38,567,729...38,650,824
JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISO
ISS
IEA
(PMID:24448649), (PMID:32612235)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:24448649 PMID:32612235 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
phagolysosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1a coronin 1A involved_in ISO (PMID:12132654) RGD PMID:12132654 NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534
JBrowse link
G Myo7a myosin VIIA acts_upstream_of_or_within ISO MGI:2155422 (MGI:2662763|PMID:12743369) RGD PMID:12743369 MGI:2662763 NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157
JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:3606250 (MGI:3699774|PMID:11544318) RGD PMID:11544318 MGI:3699774 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Rpgr retinitis pigmentosa GTPase regulator involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr  X:12,566,447...12,628,171
Ensembl chr  X:12,566,645...12,747,882
JBrowse link
G Srpx sushi-repeat-containing protein, X-linked acts_upstream_of_or_within
involved_in
ISO
IBA
IEA
MGI:3706175 (MGI:3852261|PMID:19368996)
GO_REF:0000033
GO_REF:0000118
RGD
GO_Central
TreeGrafter
PMID:19368996 GO_REF:0000033 GO_REF:0000118 MGI:3852261 NCBI chr  X:12,676,984...12,751,296
Ensembl chr  X:12,566,645...12,747,882
JBrowse link
phagolysosome assembly involved in apoptotic cell clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab14 RAB14, member RAS oncogene family involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:18,501,953...18,523,253
Ensembl chr 3:18,501,963...18,523,172
JBrowse link
phagosome-lysosome docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (MGI:5698740|PMID:26450516) RGD PMID:26450516 MGI:5698740 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
JBrowse link
phagosome-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl8b ADP-ribosylation factor like GTPase 8B involved_in ISS
ISO
GO_REF:0000024
(PMID:21802320)
UniProt
RGD
PMID:21802320 GO_REF:0000024 NCBI chr 4:141,748,634...141,792,605
Ensembl chr 4:141,748,587...141,792,596
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (MGI:5698740|PMID:26450516) RGD PMID:26450516 MGI:5698740 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
JBrowse link
G Dnajc27 DnaJ heat shock protein family (Hsp40) member C27 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 6:27,068,713...27,098,449
Ensembl chr 6:27,068,686...27,098,449
JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing involved_in ISO
IBA
(PMID:28779020)
GO_REF:0000033
(MGI:6103777|PMID:28779020)
RGD
GO_Central
PMID:28779020 GO_REF:0000033 MGI:6103777 NCBI chr 9:66,563,747...66,657,873
Ensembl chr 9:66,563,727...66,657,868
JBrowse link
G Pla2g5 phospholipase A2, group V involved_in ISS
ISO
GO_REF:0000024
(MGI:3841317|PMID:19342668)
UniProt
RGD
PMID:19342668 GO_REF:0000024 MGI:3841317 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658
JBrowse link
G Rab20 RAB20, member RAS oncogene family involved_in ISO (PMID:21255211) RGD PMID:21255211 NCBI chr16:78,019,337...78,043,529
Ensembl chr16:78,019,337...78,043,529
JBrowse link
G Rab29 RAB29, member RAS oncogene family involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr13:43,307,757...43,313,420
Ensembl chr13:43,307,775...43,313,417
JBrowse link
G Rab34 RAB34, member RAS oncogene family involved_in ISS
IBA
IEA
ISO
GO_REF:0000024
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
(MGI:5467668|PMID:23197834)
(PMID:21255211)
UniProt
GO_Central
TreeGrafter
Ensembl
RGD
PMID:21255211 PMID:23197834 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:5467668 NCBI chr10:63,083,319...63,087,538
Ensembl chr10:63,083,338...63,087,538
JBrowse link
G Rab38 RAB38, member RAS oncogene family involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 1:142,182,566...142,262,923
Ensembl chr 1:142,182,556...142,262,924
JBrowse link
G Rab39a RAB39A, member RAS oncogene family involved_in ISO
IBA
(PMID:21255211)
GO_REF:0000033
RGD
GO_Central
PMID:21255211 GO_REF:0000033 NCBI chr 8:54,088,246...54,105,867
Ensembl chr 8:54,088,129...54,106,483
JBrowse link
G Rab7a RAB7A, member RAS oncogene family involved_in ISO
IBA
IEA
ISS
(PMID:21255211)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000024
RGD
GO_Central
TreeGrafter
UniProt
PMID:21255211 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889
JBrowse link
G Rab7b Rab7b, member RAS oncogene family involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:43,121,168...43,147,581
Ensembl chr13:43,121,226...43,147,581
JBrowse link
G Syt7 synaptotagmin 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:3690533|PMID:16982801)
UniProt
RGD
PMID:16982801 GO_REF:0000024 MGI:3690533 NCBI chr 1:207,031,359...207,093,787
Ensembl chr 1:207,031,592...207,089,026
JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISS
ISO
GO_REF:0000024
(MGI:5693670|PMID:26317472)
UniProt
RGD
PMID:26317472 GO_REF:0000024 MGI:5693670 NCBI chr14:1,073,410...1,089,764
Ensembl chr14:1,073,523...1,089,819
JBrowse link
phagosome-lysosome fusion involved in apoptotic cell clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spg11 SPG11 vesicle trafficking associated, spatacsin acts_upstream_of_or_within ISO MGI:4377985 (MGI:5749311|PMID:26284655) RGD PMID:26284655 MGI:5749311 NCBI chr 3:109,007,658...109,072,904
Ensembl chr 3:109,008,135...109,072,911
JBrowse link
positive regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa8 heat shock protein family A (Hsp70) member 8 IMP RGD PMID:9038169 RGD:10059368 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:19787053) RGD PMID:19787053 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807
JBrowse link
positive regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grn granulin precursor involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:28073925)
GO_REF:0000107
(MGI:5905514|PMID:28073925)
UniProt
RGD
Ensembl
PMID:28073925 GO_REF:0000024 GO_REF:0000107 MGI:5905514 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Irgm immunity-related GTPase M involved_in ISO (PMID:32753672) RGD PMID:32753672 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578
JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 involved_in ISO (PMID:25720963) RGD PMID:25720963 NCBI chr12:1,560,341...1,574,252
Ensembl chr12:1,560,359...1,574,252
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta involved_in ISO (PMID:25720963), (PMID:32753672) RGD PMID:25720963 PMID:32753672 NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981
JBrowse link
regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC681325 hypothetical protein LOC681325 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:74,312,698...74,316,311
Ensembl chr  X:74,312,661...74,316,635
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:22012985) RGD PMID:22012985 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Spns1 SPNS lysolipid transporter 1, lysophospholipid acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:7345668|PMID:36161949)
GO_REF:0000107
RGD
Ensembl
PMID:36161949 GO_REF:0000107 MGI:7345668 NCBI chr 1:180,942,088...180,949,415
Ensembl chr 1:180,942,088...180,949,370
JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO
IBA
(PMID:31001245)
GO_REF:0000033
RGD
GO_Central
PMID:31001245 GO_REF:0000033 NCBI chr  X:50,403,962...50,423,141
Ensembl chr  X:50,361,248...50,423,269
JBrowse link
G Tmem165 transmembrane protein 165 involved_in ISO
ISS
(PMID:23569283)
GO_REF:0000024
RGD
UniProt
PMID:23569283 GO_REF:0000024 NCBI chr14:31,993,489...32,018,717
Ensembl chr14:31,993,493...32,018,717
JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISS
ISO
GO_REF:0000024
(PMID:35750034)
(MGI:5693670|PMID:26317472)
UniProt
RGD
PMID:26317472 PMID:35750034 GO_REF:0000024 MGI:5693670 NCBI chr14:1,073,410...1,089,764
Ensembl chr14:1,073,523...1,089,819
JBrowse link
G Vps33a VPS33A core subunit of CORVET and HOPS complexes involved_in ISO
IEA
ISS
(PMID:28013294)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:28013294 GO_REF:0000024 GO_REF:0000107 NCBI chr12:33,024,596...33,051,399
Ensembl chr12:33,024,650...33,051,393
JBrowse link
regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Laptm4b lysosomal protein transmembrane 4 beta involved_in ISO
IEA
ISS
(PMID:26280656)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:26280656 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:65,434,525...65,477,386
Ensembl chr 7:65,434,394...65,477,383
JBrowse link
regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grn granulin precursor acts_upstream_of_or_within ISO MGI:3762618 (MGI:6101836|PMID:28728022) RGD PMID:28728022 MGI:6101836 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Laptm4b lysosomal protein transmembrane 4 beta involved_in ISO
IEA
ISS
(PMID:26280656)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:26280656 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:65,434,525...65,477,386
Ensembl chr 7:65,434,394...65,477,383
JBrowse link
G Tmem106b transmembrane protein 106B acts_upstream_of_or_within ISO MGI:5319917 (MGI:6101836|PMID:28728022) RGD PMID:28728022 MGI:6101836 NCBI chr 4:41,328,125...41,347,315
Ensembl chr 4:41,327,994...41,345,619
JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:3052754 (MGI:5460923|PMID:23160154) RGD PMID:23160154 MGI:5460923 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20328
    cellular process 18788
      cellular component organization or biogenesis 7188
        cellular component organization 6877
          organelle organization 3816
            vacuole organization 224
              lytic vacuole organization 97
                lysosome organization + 97
paths to the root