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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of lysosomal lumen pH
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Accession:GO:0035751 term browser browse the term
Definition:Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.


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regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC681325 hypothetical protein LOC681325 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:80,359,555...80,363,168
Ensembl chr  X:80,359,555...80,363,168
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:22012985) RGD PMID:22012985 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in IBA
ISO
PMID:21873635
(PMID:31001245)
RGD PMID:31001245, PMID:21873635 RGD:13792537 NCBI chr  X:54,390,733...54,409,466
Ensembl chr  X:54,390,733...54,409,466
JBrowse link
G Tmem165 transmembrane protein 165 involved_in ISO
ISS
(PMID:23569283)
GO_REF:0000024
RGD
UniProt
PMID:23569283 GO_REF:0000024 NCBI chr14:34,503,037...34,528,262
Ensembl chr14:34,503,038...34,528,262
JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISS
ISO
GO_REF:0000024
(MGI:5693670|PMID:26317472)
UniProt
RGD
PMID:26317472 GO_REF:0000024 MGI:5693670 NCBI chr14:2,083,745...2,100,006
Ensembl chr14:2,083,712...2,100,005
JBrowse link
G Vps33a VPS33A core subunit of CORVET and HOPS complexes involved_in ISO
ISS
(PMID:28013294)
GO_REF:0000024
RGD
UniProt
PMID:28013294 GO_REF:0000024 NCBI chr12:38,459,816...38,482,903
Ensembl chr12:38,459,832...38,484,512
JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 involved_in ISO
ISS
(PMID:32276428)
GO_REF:0000024
RGD
UniProt
PMID:32276428 GO_REF:0000024 NCBI chr  X:11,137,889...11,164,854
Ensembl chr  X:11,136,939...11,164,915
JBrowse link
G Ccdc115 coiled-coil domain containing 115 involved_in ISO (PMID:28296633) RGD PMID:28296633 NCBI chr 9:37,774,876...37,778,839
Ensembl chr 9:37,775,311...37,779,967
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:11722572)
UniProt
RGD
PMID:11722572, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
G Cln5 CLN5, intracellular trafficking protein involved_in ISO (PMID:11722572) RGD PMID:11722572 NCBI chr15:93,634,815...93,644,146 JBrowse link
G Cln6 CLN6, transmembrane ER protein involved_in ISO (PMID:11722572) RGD PMID:11722572 NCBI chr 8:67,733,215...67,748,170
Ensembl chr 8:67,733,215...67,748,172
JBrowse link
G Grn granulin precursor involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:28073925)
UniProt
Ensembl
RGD
PMID:28073925 GO_REF:0000024 GO_REF:0000107 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in ISO
ISS
(PMID:11722572)
PMID:8895569
RGD PMID:11722572, PMID:8895569 RGD:8553248 NCBI chr 5:140,538,260...140,558,163
Ensembl chr 5:140,538,260...140,558,162
JBrowse link
G Snapin SNAP-associated protein acts_upstream_of_or_within ISO MGI:3608768 (MGI:4879078|PMID:20920792) RGD PMID:20920792 MGI:4879078 NCBI chr 2:189,878,159...189,880,743
Ensembl chr 2:189,878,168...189,880,743
JBrowse link
G Tmem106b transmembrane protein 106B acts_upstream_of_or_within ISO MGI:5319917 (MGI:6101836|PMID:28728022) RGD PMID:28728022 MGI:6101836 NCBI chr 4:39,517,679...39,534,491
Ensembl chr 4:39,517,548...39,535,169
JBrowse link
G Tmem199 transmembrane protein 199 involved_in ISO
ISS
(PMID:28296633)
GO_REF:0000024
RGD
UniProt
PMID:28296633 GO_REF:0000024 NCBI chr10:65,775,721...65,780,293
Ensembl chr10:65,775,715...65,780,349
JBrowse link
G Tmem9 transmembrane protein 9 involved_in ISO (PMID:30374053) RGD PMID:30374053 NCBI chr13:52,854,031...52,871,300
Ensembl chr13:52,854,031...52,871,297
JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISS
ISO
GO_REF:0000024
(PMID:10924275)
UniProt
RGD
PMID:10924275 GO_REF:0000024 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19599
    cellular process 18451
      cellular component organization or biogenesis 6720
        cellular component organization 6475
          organelle organization 4054
            vacuole organization 204
              lytic vacuole organization 82
                lysosome organization 82
                  regulation of lysosomal lumen pH 17
                    lysosomal lumen acidification 11
                    lysosomal lumen pH elevation 1
Path 2
Term Annotations click to browse term
  biological_process 19599
    biological regulation 13562
      regulation of biological quality 4167
        homeostatic process 1979
          chemical homeostasis 1348
            ion homeostasis 868
              cation homeostasis 809
                monovalent inorganic cation homeostasis 159
                  cellular monovalent inorganic cation homeostasis 108
                    regulation of cellular pH 82
                      regulation of intracellular pH 73
                        regulation of lysosomal lumen pH 17
                          lysosomal lumen acidification 11
                          lysosomal lumen pH elevation 1
paths to the root