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ONTOLOGY REPORT - ANNOTATIONS


Term:lysosome organization
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Accession:GO:0007040 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
Synonyms:exact_synonym: lysosome organisation
 related_synonym: lysosome organization and biogenesis


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lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07008608.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 2:66,600,151...66,608,324 JBrowse link
G AABR07019209.2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr15:93,634,820...93,639,250 JBrowse link
G AABR07026291.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 Ensembl chr16:70,778,913...70,831,164 JBrowse link
G AABR07028902.1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr17:90,370,882...90,522,091 JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 involved_in ISO (PMID:15163665) RGD PMID:15163665 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Acp2 acid phosphatase 2, lysosomal involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2180084|MGI:3574793 (MGI:3522374|PMID:15604265), (MGI:894905|PMID:9228031)
RGD PMID:9228031 PMID:15604265, PMID:21873635 MGI:3522374 MGI:894905, RGD:13792537 NCBI chr 3:80,020,346...80,030,365
Ensembl chr 3:80,021,440...80,030,363
JBrowse link
G Acp3 acid phosphatase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:112,838,574...112,884,062
Ensembl chr 8:112,834,707...112,884,077
JBrowse link
G Acp4 acid phosphatase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:100,226,311...100,234,536
Ensembl chr 1:100,227,157...100,234,040
JBrowse link
G Aktip AKT interacting protein involved_in ISO
ISS
(PMID:18799622)
GO_REF:0000024
RGD
UniProt
PMID:18799622 GO_REF:0000024 NCBI chr19:17,290,048...17,300,054
Ensembl chr19:17,290,178...17,300,050
JBrowse link
G Ap3b1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within ISO (MGI:1330543|PMID:9931340), (MGI:6415001|PMID:30786955) RGD PMID:9931340 PMID:30786955 MGI:1330543 MGI:6415001 NCBI chr 2:24,022,815...24,227,522
Ensembl chr 2:24,024,791...24,226,224
JBrowse link
G Becn1 beclin 1 acts_upstream_of_or_within ISO MGI:2683696 (MGI:3801567|PMID:18497889) RGD PMID:18497889 MGI:3801567 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Chmp5 charged multivesicular body protein 5 acts_upstream_of_or_within ISO MGI:3626293 (MGI:3622513|PMID:16567502) RGD PMID:16567502 MGI:3622513 NCBI chr 5:57,267,312...57,284,455
Ensembl chr 5:57,267,312...57,284,448
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1933976|MGI:2388887|MGI:3623134 (MGI:1337525|PMID:10191119), (MGI:1343910|PMID:10440905), (MGI:1346962|PMID:10527801), (MGI:3527911|PMID:15588329)
RGD PMID:10191119 PMID:10440905 PMID:10527801 PMID:15588329, PMID:21873635 MGI:1337525 MGI:1343910 MGI:1346962 MGI:3527911, RGD:13792537 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
G Cln5 CLN5, intracellular trafficking protein acts_upstream_of_or_within ISO MGI:3521802 (MGI:3512689|PMID:15459177) RGD PMID:15459177 MGI:3512689 NCBI chr15:93,634,815...93,644,146 JBrowse link
G Cln6 CLN6, transmembrane ER protein involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2159328 (MGI:1203267|PMID:9600738), (MGI:5751614|PMID:26681805)
RGD PMID:9600738 PMID:26681805, PMID:21873635 MGI:1203267 MGI:5751614, RGD:13792537 NCBI chr 8:67,733,215...67,748,170
Ensembl chr 8:67,733,215...67,748,172
JBrowse link
G Cln8 CLN8, transmembrane ER and ERGIC protein acts_upstream_of_or_within ISO MGI:1856959 (MGI:1333651|PMID:10087069), (MGI:65559|PMID:8144516), (MGI:66707|PMID:8160780), (MGI:71226|PMID:7613514) RGD PMID:7613514 PMID:8144516 PMID:8160780 PMID:10087069 MGI:1333651 MGI:65559 MGI:66707 MGI:71226 NCBI chr16:79,828,321...79,838,212
Ensembl chr16:79,828,324...79,838,212
JBrowse link
G Clvs1 clavesin 1 involved_in IBA
IMP
IEA
PMID:21873635
PMID:19651769
GO_REF:0000002
InterPro PMID:21873635, PMID:19651769 GO_REF:0000002, RGD:13792537, RGD:8553526 NCBI chr 5:22,380,318...22,580,391
Ensembl chr 5:22,380,334...22,578,297
JBrowse link
G Clvs2 clavesin 2 involved_in IMP
IBA
PMID:19651769
PMID:21873635
UniProt
GO_Central
PMID:19651769, PMID:21873635 RGD:8553526, RGD:13792537 NCBI chr 1:25,173,089...25,217,625
Ensembl chr 1:25,173,242...25,296,927
JBrowse link
G Fhip1b FHF complex subunit HOOK interacting protein 1B involved_in ISS
ISO
GO_REF:0000024
(PMID:18799622)
UniProt
RGD
PMID:18799622 GO_REF:0000024 NCBI chr 1:170,216,505...170,238,898
Ensembl chr 1:170,212,817...170,238,890
JBrowse link
G Gaa alpha glucosidase involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
MGI:2148550|MGI:2179961 (MGI:1195358|PMID:9384603), (MGI:1275872|PMID:9668092), (MGI:1346721|PMID:10547605), (MGI:2136118|PMID:11328962), (MGI:3618942|PMID:15169761), (MGI:3664400|PMID:12115977)
PMID:21873635
(PMID:7717400)
Ensembl
RGD
PMID:7717400 PMID:9384603 PMID:9668092 PMID:10547605 PMID:11328962 PMID:12115977 PMID:15169761, PMID:21873635 GO_REF:0000107 MGI:1195358 MGI:1275872 MGI:1346721 MGI:2136118 MGI:3618942 MGI:3664400, RGD:13792537 NCBI chr10:108,395,873...108,412,999
Ensembl chr10:108,395,860...108,413,059
JBrowse link
G Gba glucosylceramidase beta involved_in ISO (PMID:27378698)
(MGI:5817293|PMID:27378698)
RGD PMID:27378698 MGI:5817293 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601
JBrowse link
G Gnptab N-acetylglucosamine-1-phosphate transferase subunits alpha and beta involved_in ISO (PMID:21719679) RGD PMID:21719679 NCBI chr 7:28,956,363...29,023,232
Ensembl chr 7:28,956,512...29,022,868
JBrowse link
G Grn granulin precursor involved_in ISS
ISO
GO_REF:0000024
(MGI:6274951|PMID:27789271)
UniProt
RGD
PMID:27789271 GO_REF:0000024 MGI:6274951 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Hexa hexosaminidase subunit alpha acts_upstream_of_or_within ISO MGI:1857181|MGI:2429698|MGI:3581540|MGI:96074 (MGI:1097747|PMID:9302266), (MGI:1271008|PMID:9645704), (MGI:1352198|PMID:10591619), (MGI:3033296|PMID:14972652), (MGI:69059|PMID:7937929), (MGI:77946|PMID:8747922), (MGI:83770|PMID:8896570), (MGI:86923|PMID:9103204), (MGI:894634|PMID:9184660) RGD PMID:7937929 PMID:8747922 PMID:8896570 PMID:9103204 PMID:9184660 PMID:9302266 PMID:9645704 PMID:10591619 PMID:14972652 MGI:1097747 MGI:1271008 MGI:1352198 MGI:3033296 MGI:69059 MGI:77946 MGI:83770 MGI:86923 MGI:894634 NCBI chr 8:64,325,435...64,350,775
Ensembl chr 8:64,325,435...64,350,773
JBrowse link
G Hexb hexosaminidase subunit beta involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2429701|MGI:96073 (MGI:1271008|PMID:9645704), (MGI:78473|PMID:8789434), (MGI:83770|PMID:8896570), (MGI:894634|PMID:9184660)
Ensembl
RGD
PMID:8789434 PMID:8896570 PMID:9184660 PMID:9645704 GO_REF:0000107 MGI:1271008 MGI:78473 MGI:83770 MGI:894634 NCBI chr 2:27,983,925...28,003,260
Ensembl chr 2:27,984,117...28,003,186
JBrowse link
G Hook1 hook microtubule-tethering protein 1 involved_in ISO (PMID:18799622) RGD PMID:18799622 NCBI chr 5:114,940,053...115,000,691
Ensembl chr 5:114,940,053...115,000,691
JBrowse link
G Hook2 hook microtubule-tethering protein 2 involved_in ISO (PMID:18799622) RGD PMID:18799622 NCBI chr19:26,106,713...26,119,353
Ensembl chr19:26,106,838...26,119,352
JBrowse link
G Hook3 hook microtubule-tethering protein 3 involved_in ISO (PMID:18799622) RGD PMID:18799622 NCBI chr16:70,710,347...70,818,789 JBrowse link
G Hps1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 acts_upstream_of_or_within ISO (MGI:6415001|PMID:30786955) RGD PMID:30786955 MGI:6415001 NCBI chr 1:261,989,178...262,015,282
Ensembl chr 1:261,989,178...262,015,153
JBrowse link
G Hps4 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 involved_in ISO (PMID:12663659) RGD PMID:12663659 NCBI chr12:50,285,239...50,315,893
Ensembl chr12:50,285,278...50,314,406
JBrowse link
G Idua alpha-L-iduronidase acts_upstream_of_or_within ISO MGI:2176236|MGI:4415188 (MGI:4414887|PMID:19751987), (MGI:86916|PMID:9097952) RGD PMID:9097952 PMID:19751987 MGI:4414887 MGI:86916 NCBI chr14:2,041,828...2,056,762
Ensembl chr14:2,042,411...2,056,762
JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:4887551|PMID:19177150)
UniProt
RGD
PMID:19177150 GO_REF:0000024 MGI:4887551 NCBI chr 1:166,991,474...166,997,045
Ensembl chr 1:166,991,474...166,997,045
JBrowse link
G LOC100361543 RhoA activator C11orf59-like involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:37,261,428...37,262,470
Ensembl chr 1:166,991,474...166,997,045
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:25416817) RGD PMID:25416817 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Lyst lysosomal trafficking regulator acts_upstream_of_or_within ISO MGI:1855968|MGI:1855969 (MGI:1099544|PMID:9368050), (MGI:53816|PMID:4697831), (MGI:53992|PMID:1113502), (MGI:55104|PMID:6170520), (MGI:56449|PMID:4031470) RGD PMID:1113502 PMID:4031470 PMID:4697831 PMID:6170520 PMID:9368050 MGI:1099544 MGI:53816 MGI:53992 MGI:55104 MGI:56449 NCBI chr17:90,323,055...90,522,091 JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:21719679)
UniProt
RGD
PMID:21719679 GO_REF:0000024 NCBI chr19:52,146,507...52,206,310
Ensembl chr19:52,146,808...52,206,310
JBrowse link
G Mfsd8 major facilitator superfamily domain containing 8 acts_upstream_of_or_within ISO MGI:4456699 (MGI:5575728|PMID:24423645), (MGI:5751614|PMID:26681805) RGD PMID:24423645 PMID:26681805 MGI:5575728 MGI:5751614 NCBI chr 2:127,706,618...127,784,129
Ensembl chr 2:127,699,761...127,781,003
JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISO
ISS
(PMID:22692423)
GO_REF:0000024
RGD
UniProt
PMID:22692423 GO_REF:0000024 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Myo7a myosin VIIA involved_in ISS
ISO
GO_REF:0000024
(PMID:16001398)
UniProt
RGD
PMID:16001398 GO_REF:0000024 NCBI chr 1:163,001,313...163,071,545
Ensembl chr 1:163,001,875...163,071,508
JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO MGI:1934018 (MGI:3769195|PMID:17712420) RGD PMID:17712420 MGI:3769195 NCBI chr10:88,979,363...88,986,879
Ensembl chr10:88,979,383...88,986,867
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 acts_upstream_of_or_within ISO MGI:2176390|MGI:3527191 (MGI:3612221|PMID:16368712), (MGI:3654230|PMID:16542649) RGD PMID:16368712 PMID:16542649 MGI:3612221 MGI:3654230 NCBI chr 5:140,538,260...140,558,163
Ensembl chr 5:140,538,260...140,558,162
JBrowse link
G Snapin SNAP-associated protein involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3608768 (MGI:4879078|PMID:20920792)
RGD PMID:20920792, PMID:21873635 MGI:4879078, RGD:13792537 NCBI chr 2:189,878,159...189,880,743
Ensembl chr 2:189,878,168...189,880,743
JBrowse link
G Spg11 SPG11 vesicle trafficking associated, spatacsin acts_upstream_of_or_within ISO MGI:4377985 (MGI:5749311|PMID:26284655) RGD PMID:26284655 MGI:5749311 NCBI chr 3:113,999,600...114,064,438
Ensembl chr 3:113,999,719...114,065,170
JBrowse link
G Tfeb transcription factor EB involved_in ISO (PMID:22692423), (PMID:23434374) RGD PMID:22692423 PMID:23434374 NCBI chr 9:15,208,141...15,264,101
Ensembl chr 9:15,207,822...15,214,596
JBrowse link
G Tmem106b transmembrane protein 106B involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5588048|PMID:25066864)
RGD PMID:25066864, PMID:21873635 MGI:5588048, RGD:13792537 NCBI chr 4:39,517,679...39,534,491
Ensembl chr 4:39,517,548...39,535,169
JBrowse link
G Tpcn2 two pore segment channel 2 involved_in ISO UniProtKB:Q8NHX9 (PMID:25416817) RGD PMID:25416817 NCBI chr 1:218,419,182...218,448,902
Ensembl chr 1:218,419,184...218,448,877
JBrowse link
G Tpp1 tripeptidyl peptidase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3521972 (MGI:3522013|PMID:15483130)
Ensembl
RGD
PMID:15483130 GO_REF:0000107 MGI:3522013 NCBI chr 1:170,588,036...170,594,159
Ensembl chr 1:170,588,035...170,594,168
JBrowse link
G Vps18 VPS18 core subunit of CORVET and HOPS complexes involved_in IBA
ISO
PMID:21873635
(PMID:18799622)
RGD PMID:18799622, PMID:21873635 RGD:13792537 NCBI chr 3:111,097,352...111,108,206
Ensembl chr 3:111,097,326...111,108,295
JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO (MGI:5694519|PMID:26203154) RGD PMID:26203154 MGI:5694519 NCBI chr19:27,464,937...27,500,636
Ensembl chr19:27,464,937...27,500,636
JBrowse link
G Washc5 WASH complex subunit 5 acts_upstream_of_or_within ISO MGI:6246601 (MGI:6199426|PMID:30061306) RGD PMID:30061306 MGI:6199426 NCBI chr 7:99,625,379...99,677,237
Ensembl chr 7:99,625,619...99,677,268
JBrowse link
G Zkscan3 zinc finger with KRAB and SCAN domains 3 involved_in ISO (PMID:23434374) RGD PMID:23434374 NCBI chr17:45,247,724...45,263,422
Ensembl chr17:45,247,776...45,263,418
JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 involved_in ISO
ISS
(PMID:32276428)
GO_REF:0000024
RGD
UniProt
PMID:32276428 GO_REF:0000024 NCBI chr  X:11,137,889...11,164,854
Ensembl chr  X:11,136,939...11,164,915
JBrowse link
G Ccdc115 coiled-coil domain containing 115 involved_in ISO (PMID:28296633) RGD PMID:28296633 NCBI chr 9:37,774,876...37,778,839
Ensembl chr 9:37,775,311...37,779,967
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:11722572)
UniProt
RGD
PMID:11722572, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
G Cln5 CLN5, intracellular trafficking protein involved_in ISO (PMID:11722572) RGD PMID:11722572 NCBI chr15:93,634,815...93,644,146 JBrowse link
G Cln6 CLN6, transmembrane ER protein involved_in ISO (PMID:11722572) RGD PMID:11722572 NCBI chr 8:67,733,215...67,748,170
Ensembl chr 8:67,733,215...67,748,172
JBrowse link
G Grn granulin precursor involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:28073925)
UniProt
Ensembl
RGD
PMID:28073925 GO_REF:0000024 GO_REF:0000107 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in ISO
ISS
(PMID:11722572)
PMID:8895569
RGD PMID:11722572, PMID:8895569 RGD:8553248 NCBI chr 5:140,538,260...140,558,163
Ensembl chr 5:140,538,260...140,558,162
JBrowse link
G Snapin SNAP-associated protein acts_upstream_of_or_within ISO MGI:3608768 (MGI:4879078|PMID:20920792) RGD PMID:20920792 MGI:4879078 NCBI chr 2:189,878,159...189,880,743
Ensembl chr 2:189,878,168...189,880,743
JBrowse link
G Tmem106b transmembrane protein 106B acts_upstream_of_or_within ISO MGI:5319917 (MGI:6101836|PMID:28728022) RGD PMID:28728022 MGI:6101836 NCBI chr 4:39,517,679...39,534,491
Ensembl chr 4:39,517,548...39,535,169
JBrowse link
G Tmem199 transmembrane protein 199 involved_in ISO
ISS
(PMID:28296633)
GO_REF:0000024
RGD
UniProt
PMID:28296633 GO_REF:0000024 NCBI chr10:65,775,721...65,780,293
Ensembl chr10:65,775,715...65,780,349
JBrowse link
G Tmem9 transmembrane protein 9 involved_in ISO (PMID:30374053) RGD PMID:30374053 NCBI chr13:52,854,031...52,871,300
Ensembl chr13:52,854,031...52,871,297
JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISS
ISO
GO_REF:0000024
(PMID:10924275)
UniProt
RGD
PMID:10924275 GO_REF:0000024 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
lysosomal membrane organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf1 ADP-ribosylation factor 1 IDA RGD PMID:9538255 RGD:9684948 NCBI chr10:45,562,700...45,579,214
Ensembl chr10:45,563,547...45,579,029
JBrowse link
G Atp10b ATPase phospholipid transporting 10B (putative) involved_in ISO (PMID:32172343) RGD PMID:32172343 NCBI chr10:28,449,248...28,862,423
Ensembl chr10:28,449,335...28,864,255
JBrowse link
multivesicular body-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chmp3 charged multivesicular body protein 3 involved_in ISO (PMID:16554368) RGD PMID:16554368 NCBI chr 4:99,449,213...99,496,156
Ensembl chr 4:99,449,111...99,494,423
JBrowse link
negative regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1 IMP RGD PMID:25561470 RGD:11561937 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
phagolysosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1a coronin 1A involved_in ISO (PMID:12132654) RGD PMID:12132654 NCBI chr 1:198,123,883...198,128,890
Ensembl chr 1:198,123,884...198,128,857
JBrowse link
G Myo7a myosin VIIA acts_upstream_of_or_within ISO MGI:2155422 (MGI:2662763|PMID:12743369) RGD PMID:12743369 MGI:2662763 NCBI chr 1:163,001,313...163,071,545
Ensembl chr 1:163,001,875...163,071,508
JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:3606250 (MGI:3699774|PMID:11544318) RGD PMID:11544318 MGI:3699774 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G Srpx sushi-repeat-containing protein, X-linked acts_upstream_of_or_within ISO MGI:3706175 (MGI:3852261|PMID:19368996) RGD PMID:19368996 MGI:3852261 NCBI chr  X:14,146,618...14,220,756
Ensembl chr  X:14,150,038...14,220,662
JBrowse link
phagolysosome assembly involved in apoptotic cell clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab14 RAB14, member RAS oncogene family involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:14,373,270...14,395,357
Ensembl chr 3:14,373,275...14,395,362
JBrowse link
phagosome-lysosome docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (MGI:5698740|PMID:26450516) RGD PMID:26450516 MGI:5698740 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
phagosome-lysosome fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07037545.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr  X:23,416,395...23,417,122 JBrowse link
G Arl8b ADP-ribosylation factor like GTPase 8B involved_in ISS
ISO
GO_REF:0000024
(PMID:21802320)
UniProt
RGD
PMID:21802320 GO_REF:0000024 NCBI chr 4:140,837,745...140,881,866
Ensembl chr 4:140,837,745...140,881,865
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (MGI:5698740|PMID:26450516) RGD PMID:26450516 MGI:5698740 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing involved_in ISO (PMID:28779020)
(MGI:6103777|PMID:28779020)
RGD PMID:28779020 MGI:6103777 NCBI chr 9:71,911,744...72,005,816
Ensembl chr 9:71,915,421...72,005,838
JBrowse link
G Pla2g5 phospholipase A2, group V involved_in ISS
ISO
GO_REF:0000024
(MGI:3841317|PMID:19342668)
UniProt
RGD
PMID:19342668 GO_REF:0000024 MGI:3841317 NCBI chr 5:157,247,601...157,268,968
Ensembl chr 5:157,247,781...157,268,903
JBrowse link
G Rab20 RAB20, member RAS oncogene family involved_in ISO (PMID:21255211) RGD PMID:21255211 NCBI chr16:83,358,116...83,382,326
Ensembl chr16:83,358,116...83,382,326
JBrowse link
G Rab34 RAB34, member RAS oncogene family involved_in IBA
IEA
ISO
ISS
PMID:21873635
GO_REF:0000107
(MGI:5467668|PMID:23197834)
(PMID:21255211)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:21255211 PMID:23197834, PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5467668, RGD:13792537 NCBI chr10:65,448,111...65,452,178
Ensembl chr10:65,448,950...65,452,177
JBrowse link
G Rab39a RAB39A, member RAS oncogene family involved_in ISO (PMID:21255211) RGD PMID:21255211 NCBI chr 8:58,275,984...58,292,995
Ensembl chr 8:58,272,098...58,293,102
JBrowse link
G Rab7a RAB7A, member RAS oncogene family involved_in ISO
IBA
ISS
(PMID:21255211)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:21255211, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 4:119,910,461...119,963,065
Ensembl chr 4:119,910,478...119,959,173
JBrowse link
G Rab7b Rab7b, member RAS oncogene family involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:48,456,143...48,483,714
Ensembl chr13:48,455,923...48,482,138
JBrowse link
G Syt7 synaptotagmin 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:3690533|PMID:16982801)
UniProt
RGD
PMID:16982801 GO_REF:0000024 MGI:3690533 NCBI chr 1:226,435,816...226,498,008
Ensembl chr 1:226,435,979...226,493,377
JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISS
ISO
GO_REF:0000024
(MGI:5693670|PMID:26317472)
UniProt
RGD
PMID:26317472 GO_REF:0000024 MGI:5693670 NCBI chr14:2,083,745...2,100,006
Ensembl chr14:2,083,712...2,100,005
JBrowse link
phagosome-lysosome fusion involved in apoptotic cell clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spg11 SPG11 vesicle trafficking associated, spatacsin acts_upstream_of_or_within ISO MGI:4377985 (MGI:5749311|PMID:26284655) RGD PMID:26284655 MGI:5749311 NCBI chr 3:113,999,600...114,064,438
Ensembl chr 3:113,999,719...114,065,170
JBrowse link
positive regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa8 heat shock protein family A (Hsp70) member 8 IMP RGD PMID:9038169 RGD:10059368 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:19787053) RGD PMID:19787053 NCBI chr 5:149,015,793...149,069,719
Ensembl chr 5:149,047,681...149,069,719
JBrowse link
G Mt3 metallothionein 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:4881636|PMID:20544854)
UniProt
RGD
PMID:20544854 GO_REF:0000024 MGI:4881636 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
positive regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grn granulin precursor involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:28073925)
GO_REF:0000107
(MGI:5905514|PMID:28073925)
UniProt
RGD
Ensembl
PMID:28073925 GO_REF:0000024 GO_REF:0000107 MGI:5905514 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC681325 hypothetical protein LOC681325 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:80,359,555...80,363,168
Ensembl chr  X:80,359,555...80,363,168
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:22012985) RGD PMID:22012985 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in IBA
ISO
PMID:21873635
(PMID:31001245)
RGD PMID:31001245, PMID:21873635 RGD:13792537 NCBI chr  X:54,390,733...54,409,466
Ensembl chr  X:54,390,733...54,409,466
JBrowse link
G Tmem165 transmembrane protein 165 involved_in ISO
ISS
(PMID:23569283)
GO_REF:0000024
RGD
UniProt
PMID:23569283 GO_REF:0000024 NCBI chr14:34,503,037...34,528,262
Ensembl chr14:34,503,038...34,528,262
JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISS
ISO
GO_REF:0000024
(MGI:5693670|PMID:26317472)
UniProt
RGD
PMID:26317472 GO_REF:0000024 MGI:5693670 NCBI chr14:2,083,745...2,100,006
Ensembl chr14:2,083,712...2,100,005
JBrowse link
G Vps33a VPS33A core subunit of CORVET and HOPS complexes involved_in ISO
ISS
(PMID:28013294)
GO_REF:0000024
RGD
UniProt
PMID:28013294 GO_REF:0000024 NCBI chr12:38,459,816...38,482,903
Ensembl chr12:38,459,832...38,484,512
JBrowse link
regulation of lysosomal membrane permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Laptm4b lysosomal protein transmembrane 4 beta involved_in ISO
ISS
(PMID:26280656)
GO_REF:0000024
RGD
UniProt
PMID:26280656 GO_REF:0000024 NCBI chr 7:72,924,911...72,968,099
Ensembl chr 7:72,924,799...72,968,101
JBrowse link
regulation of lysosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grn granulin precursor acts_upstream_of_or_within ISO MGI:3762618 (MGI:6101836|PMID:28728022) RGD PMID:28728022 MGI:6101836 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Laptm4b lysosomal protein transmembrane 4 beta involved_in ISO
ISS
(PMID:26280656)
GO_REF:0000024
RGD
UniProt
PMID:26280656 GO_REF:0000024 NCBI chr 7:72,924,911...72,968,099
Ensembl chr 7:72,924,799...72,968,101
JBrowse link
G Tmem106b transmembrane protein 106B acts_upstream_of_or_within ISO MGI:5319917 (MGI:6101836|PMID:28728022) RGD PMID:28728022 MGI:6101836 NCBI chr 4:39,517,679...39,534,491
Ensembl chr 4:39,517,548...39,535,169
JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:3052754 (MGI:5460923|PMID:23160154) RGD PMID:23160154 MGI:5460923 NCBI chr 8:117,796,127...117,797,427
Ensembl chr 8:117,796,128...117,797,427
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    cellular process 18457
      cellular component organization or biogenesis 6724
        cellular component organization 6479
          organelle organization 4057
            vacuole organization 203
              lytic vacuole organization 82
                lysosome organization 82
                  lysosomal membrane organization + 7
                  negative regulation of lysosome organization 1
                  phagolysosome assembly + 18
                  positive regulation of lysosome organization 1
                  regulation of lysosomal lumen pH + 17
                  regulation of lysosome organization + 5
paths to the root