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ONTOLOGY REPORT - ANNOTATIONS

Term:small GTPase-mediated signal transduction
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Accession:GO:0007264 term browser browse the term
Definition:An intracellular signaling cassette in which a small monomeric GTPase relays a signal.
Synonyms:narrow_synonym: Ras family protein signal transduction


show annotations for term's descendants           Sort by:
small GTPase-mediated signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARHGAP1 Rho GTPase activating protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:8253717), (PMID:8288572) MGI
TreeGrafter
Ensembl		 PMID:8253717 PMID:8288572 GO_REF:0000107 GO_REF:0000118 NCBI chr11:46,626,174...46,651,308
Ensembl chr11:47,185,415...47,209,765 		JBrowse link
G ARHGAP18 Rho GTPase activating protein 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:127,368,377...127,558,136
Ensembl chr 6:131,477,383...131,609,221 		JBrowse link
G ARHGAP30 Rho GTPase activating protein 30 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:136,459,485...136,482,384
Ensembl chr 1:140,372,824...140,395,323 		JBrowse link
G ARHGAP31 Rho GTPase activating protein 31 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11744688) Ensembl
MGI
TreeGrafter		 PMID:11744688 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:116,412,238...116,536,900
Ensembl chr 3:123,324,166...123,450,236 		JBrowse link
G ARHGAP32 Rho GTPase activating protein 32 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:123,780,028...124,096,494
Ensembl chr11:127,684,622...127,909,822 		JBrowse link
G ARHGAP33 Rho GTPase activating protein 33 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:32,704,877...32,710,778
Ensembl chr19:41,439,010...41,452,173 		JBrowse link
G ARHGAP8 Rho GTPase activating protein 8 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:25,650,927...25,755,578
Ensembl chr22:43,760,203...43,820,836
Ensembl chr22:43,760,203...43,820,836 		JBrowse link
G ARHGEF18 Rho/Rac guanine nucleotide exchange factor 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14512443) InterPro
MGI		 PMID:14512443 GO_REF:0000002 NCBI chr19:6,677,468...6,763,286 JBrowse link
G ARHGEF7 Rho guanine nucleotide exchange factor 7 ISO RGD PMID:12226077 RGD:633693 NCBI chr13:92,246,107...92,436,173
Ensembl chr13:111,427,905...111,545,413 		JBrowse link
G ARL3 ADP ribosylation factor like GTPase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:99,271,620...99,312,784
Ensembl chr10:102,735,325...102,775,849 		JBrowse link
G BCAR3 BCAR3 adaptor protein, NSP family member involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:96,230,498...96,508,028
Ensembl chr 1:94,960,966...95,080,565 		JBrowse link
G BCR BCR activator of RhoGEF and GTPase involved_in ISO (PMID:23940119) UniProt PMID:23940119
G CCDC88A coiled-coil domain containing 88A involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:55,445,060...55,576,479
Ensembl chr2A:56,589,221...56,715,362 		JBrowse link
G CCDC88C coiled-coil domain containing 88C involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:71,897,602...72,044,242
Ensembl chr14:91,244,434...91,393,715 		JBrowse link
G CDC42 cell division cycle 42 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:21,245,970...21,286,210 JBrowse link
G CHM CHM Rab escort protein involved_in IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr  X:74,928,576...75,115,733
Ensembl chr  X:85,038,154...85,224,761 		JBrowse link
G DAB1 DAB adaptor protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15062102) Ensembl
MGI		 PMID:15062102 GO_REF:0000107 NCBI chr 1:56,279,089...57,529,881
Ensembl chr 1:58,005,136...58,286,708 		JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11116152) Ensembl
MGI		 PMID:11116152 GO_REF:0000107 NCBI chr16:3,351,825...3,381,914
Ensembl chr16:4,519,965...4,550,786 		JBrowse link
G DOCK1 dedicator of cytokinesis 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr10:123,485,345...124,041,337
Ensembl chr10:127,803,236...128,288,897 		JBrowse link
G DOCK10 dedicator of cytokinesis 10 involved_in IEA InterPro GO_REF:0000002 NCBI chr2B:112,006,479...112,283,939
Ensembl chr2B:230,578,452...230,854,877 		JBrowse link
G DOCK11 dedicator of cytokinesis 11 involved_in IEA InterPro GO_REF:0000002 NCBI chr  X:107,502,955...107,694,069
Ensembl chr  X:117,952,995...118,161,009 		JBrowse link
G DOCK2 dedicator of cytokinesis 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:165,000,368...165,447,148
Ensembl chr 5:171,778,952...172,206,238 		JBrowse link
G DOCK3 dedicator of cytokinesis 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr 3:50,603,069...51,314,876
Ensembl chr 3:51,944,251...52,546,569 		JBrowse link
G DOCK4 dedicator of cytokinesis 4 involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:103,697,418...104,169,469
Ensembl chr 7:116,400,535...116,871,755 		JBrowse link
G DOCK5 dedicator of cytokinesis 5 involved_in IEA InterPro GO_REF:0000002 NCBI chr 8:24,463,582...24,696,736
Ensembl chr 8:21,372,756...21,605,877 		JBrowse link
G DOCK6 dedicator of cytokinesis 6 involved_in IEA InterPro GO_REF:0000002 NCBI chr19:10,747,850...10,811,483
Ensembl chr19:11,459,062...11,513,220 		JBrowse link
G DOCK7 dedicator of cytokinesis 7 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:61,713,217...61,946,371
Ensembl chr 1:63,529,227...63,740,970 		JBrowse link
G DOCK8 dedicator of cytokinesis 8 involved_in IEA InterPro GO_REF:0000002 NCBI chr 9:6,791...256,837
Ensembl chr 9:201,156...446,910 		JBrowse link
G DOCK9 dedicator of cytokinesis 9 involved_in IEA InterPro GO_REF:0000002 NCBI chr13:79,964,350...80,256,416
Ensembl chr13:99,106,971...99,325,589 		JBrowse link
G GDI1 GDP dissociation inhibitor 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr  X:143,878,690...143,885,251
Ensembl chr  X:153,749,661...153,755,877 		JBrowse link
G GDI2 GDP dissociation inhibitor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7782346) InterPro
MGI		 PMID:7782346 GO_REF:0000002 NCBI chr10:5,806,336...5,854,676
Ensembl chr10:5,789,496...5,839,003 		JBrowse link
G HMOX1 heme oxygenase 1 ISO RGD PMID:12511545 RGD:628519 NCBI chr22:16,388,368...16,401,289
Ensembl chr22:34,230,825...34,244,063 		JBrowse link
G HRAS HRas proto-oncogene, GTPase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14712229) Ensembl
MGI		 PMID:14712229 GO_REF:0000107 NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078 		JBrowse link
G ITSN1 intersectin 1 acts_upstream_of_or_within ISO (PMID:11744688) MGI PMID:11744688 NCBI chr21:20,009,385...20,266,835
Ensembl chr21:33,457,081...33,625,248 		JBrowse link
G KNDC1 kinase non-catalytic C-lobe domain containing 1 involved_in IEA InterPro GO_REF:0000002 Ensembl chr10:134,068,936...134,132,964 JBrowse link
G LIPA lipase A, lysosomal acid type involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22383970) Ensembl
MGI		 PMID:22383970 GO_REF:0000107 NCBI chr10:85,938,240...85,976,610
Ensembl chr10:89,477,082...89,516,874 		JBrowse link
G LOC100969771 ral-GDS-related protein involved_in IEA InterPro GO_REF:0000002 NCBI chr22:4,424,113...4,432,004 JBrowse link
G LOC100989777 ras-related C3 botulinum toxin substrate 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 6:141,918,410...141,919,483 JBrowse link
G LOC100993131 cell division control protein 42 homolog involved_in IEA InterPro GO_REF:0000002 NCBI chr 9:33,260,425...33,262,300 JBrowse link
G LRRC45 leucine rich repeat containing 45 involved_in IEA InterPro GO_REF:0000002 NCBI chr17:76,427,929...76,435,779
Ensembl chr17:82,133,217...82,143,623 		JBrowse link
G NUCB1 nucleobindin 1 involved_in ISO PMID:21653697 UniProt PMID:21653697 RGD:14929204 NCBI chr19:45,900,098...45,923,056
Ensembl chr19:54,832,426...54,855,962 		JBrowse link
G NUCB2 nucleobindin 2 involved_in ISO PMID:21653697 UniProt PMID:21653697 RGD:14929204 NCBI chr11:17,331,742...17,404,682
Ensembl chr11:17,036,038...17,072,447 		JBrowse link
G PLCD4 phospholipase C delta 4 involved_in ISO (PMID:30194280) UniProt PMID:30194280 NCBI chr2B:105,864,706...105,895,114
Ensembl chr2B:224,461,261...224,490,345 		JBrowse link
G PLCE1 phospholipase C epsilon 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr10:90,731,695...91,065,846
Ensembl chr10:94,278,550...94,575,024 		JBrowse link
G RAB4A RAB4A, member RAS oncogene family acts_upstream_of_or_within ISO (PMID:11172003) MGI PMID:11172003 NCBI chr 1:204,818,445...204,849,775
Ensembl chr 1:209,848,620...209,883,305 		JBrowse link
G RABIF RAB interacting factor involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:178,479,806...178,488,599
Ensembl chr 1:182,774,480...182,783,647 		JBrowse link
G RAC1 Rac family small GTPase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12525493), (PMID:23967341) InterPro
MGI		 PMID:12525493 PMID:23967341 GO_REF:0000002 NCBI chr 7:7,039,379...7,068,866 JBrowse link
G RAC2 Rac family small GTPase 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr22:18,138,517...18,159,023
Ensembl chr22:35,973,229...35,992,026 		JBrowse link
G RAC3 Rac family small GTPase 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr17:76,436,264...76,439,492
Ensembl chr17:82,133,217...82,143,623 		JBrowse link
G RALBP1 ralA binding protein 1 involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl
InterPro		 PMID:7623849 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:633902 NCBI chr18:4,747,555...4,810,710
Ensembl chr18:7,028,188...7,090,934 		JBrowse link
G RALGDS ral guanine nucleotide dissociation stimulator involved_in IEA InterPro GO_REF:0000002 NCBI chr 9:104,218,338...104,269,322
Ensembl chr 9:132,832,924...132,865,901 		JBrowse link
G RALGPS1 Ral GEF with PH domain and SH3 binding motif 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 9:98,033,100...98,342,582
Ensembl chr 9:126,689,557...126,992,628 		JBrowse link
G RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:154,224,362...154,411,202
Ensembl chr 1:157,916,856...158,097,550 		JBrowse link
G RAP1A RAP1A, member of RAS oncogene family acts_upstream_of_or_within ISO (PMID:12473665) MGI PMID:12473665 NCBI chr 1:114,279,255...114,376,977
Ensembl chr 1:125,971,598...125,994,813 		JBrowse link
G RAP1B RAP1B, member of RAS oncogene family acts_upstream_of_or_within ISO (PMID:14712229) MGI PMID:14712229 NCBI chr12:66,122,212...66,172,450
Ensembl chr12:68,942,053...68,955,649 		JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000117 NCBI chr 9:102,698,970...102,861,482
Ensembl chr 9:131,337,001...131,495,664 		JBrowse link
G RAPGEF2 Rap guanine nucleotide exchange factor 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 4:151,419,402...151,680,769
Ensembl chr 4:163,316,396...163,487,495 		JBrowse link
G RAPGEF3 Rap guanine nucleotide exchange factor 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr12:40,974,756...40,999,471
Ensembl chr12:41,848,785...41,873,252 		JBrowse link
G RAPGEF4 Rap guanine nucleotide exchange factor 4 involved_in IEA InterPro GO_REF:0000002 NCBI chr2B:60,022,738...60,339,981
Ensembl chr2B:177,655,733...177,793,644 		JBrowse link
G RAPGEF5 Rap guanine nucleotide exchange factor 5 involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:22,806,855...23,047,663
Ensembl chr 7:22,122,434...22,317,650 		JBrowse link
G RAPGEF6 Rap guanine nucleotide exchange factor 6 involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:126,852,474...127,064,421
Ensembl chr 5:133,018,249...133,228,851 		JBrowse link
G RAPGEFL1 Rap guanine nucleotide exchange factor like 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr17:17,093,714...17,111,187
Ensembl chr17:17,315,114...17,335,258 		JBrowse link
G RASGEF1A RasGEF domain family member 1A involved_in IEA InterPro GO_REF:0000002 NCBI chr10:40,168,940...40,241,547
Ensembl chr10:43,351,953...43,386,875 		JBrowse link
G RASGEF1B RasGEF domain family member 1B involved_in IEA InterPro GO_REF:0000002 NCBI chr 4:42,153,818...42,771,749
Ensembl chr 4:48,004,253...48,620,978 		JBrowse link
G RASGEF1C RasGEF domain family member 1C involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:175,277,643...175,313,874 JBrowse link
G RASGRF1 Ras protein specific guanine nucleotide releasing factor 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr15:57,933,152...58,063,824
Ensembl chr15:76,891,556...77,022,534 		JBrowse link
G RASGRF2 Ras protein specific guanine nucleotide releasing factor 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:34,048,832...34,326,755
Ensembl chr 5:34,359,896...34,635,488 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr15:17,417,684...17,494,333
Ensembl chr15:35,675,348...35,750,315 		JBrowse link
G RASGRP2 RAS guanyl releasing protein 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr11:60,081,781...60,101,400
Ensembl chr11:63,423,112...63,440,917 		JBrowse link
G RASGRP3 RAS guanyl releasing protein 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr2A:33,444,941...33,572,829
Ensembl chr2A:34,196,421...34,284,307 		JBrowse link
G RASGRP4 RAS guanyl releasing protein 4 involved_in IEA InterPro GO_REF:0000002 NCBI chr19:35,503,314...35,520,787
Ensembl chr19:44,074,039...44,091,623 		JBrowse link
G RGL1 ral guanine nucleotide dissociation stimulator like 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:159,166,090...159,457,883
Ensembl chr 1:163,429,258...163,614,657 		JBrowse link
G RGL2 ral guanine nucleotide dissociation stimulator like 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 6:32,863,954...32,871,684
Ensembl chr 6:33,978,024...33,985,749 		JBrowse link
G RGL3 ral guanine nucleotide dissociation stimulator like 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr19:10,932,016...10,966,701
Ensembl chr19:11,652,700...11,685,293 		JBrowse link
G RHEB Ras homolog, mTORC1 binding involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:16354680 GO_REF:0000118 RGD:1625606 NCBI chr 7:143,054,747...143,108,011 JBrowse link
G RHEBL1 RHEB like 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:39,680,095...39,686,152
Ensembl chr12:40,560,179...40,565,758 		JBrowse link
G RHOA ras homolog family member A involved_in IEA InterPro GO_REF:0000002 NCBI chr 3:49,282,009...49,339,887 JBrowse link
G RHOB ras homolog family member B involved_in IEA InterPro GO_REF:0000002 NCBI chr2A:20,433,576...20,435,986
Ensembl chr2A:20,549,254...20,549,844 		JBrowse link
G RHOBTB1 Rho related BTB domain containing 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr10:57,410,347...57,541,038
Ensembl chr10:59,740,662...59,815,536 		JBrowse link
G RHOBTB2 Rho related BTB domain containing 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 8:22,246,075...22,269,443
Ensembl chr 8:19,183,931...19,209,420 		JBrowse link
G RHOC ras homolog family member C involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:115,353,868...115,360,036
Ensembl chr 1:124,993,063...125,001,708 		JBrowse link
G RHOD ras homolog family member D involved_in IEA InterPro GO_REF:0000002 NCBI chr11:62,418,466...62,433,453
Ensembl chr11:65,736,668...65,754,761 		JBrowse link
G RHOF ras homolog family member F, filopodia associated involved_in IEA InterPro GO_REF:0000002 NCBI chr12:119,381,412...119,397,229
Ensembl chr12:122,751,751...122,766,800 		JBrowse link
G RHOG ras homolog family member G involved_in IEA InterPro GO_REF:0000002 NCBI chr11:3,698,179...3,712,402
Ensembl chr11:3,811,877...3,812,452 		JBrowse link
G RHOH ras homolog family member H involved_in IEA InterPro GO_REF:0000002 NCBI chr 4:34,517,487...34,569,934
Ensembl chr 4:40,419,549...40,420,124 		JBrowse link
G RHOJ ras homolog family member J involved_in IEA InterPro GO_REF:0000002 NCBI chr14:43,783,185...43,872,000
Ensembl chr14:62,039,418...62,126,908 		JBrowse link
G RHOT1 ras homolog family member T1 involved_in IEA InterPro GO_REF:0000002 NCBI chr17:24,523,047...24,633,559
Ensembl chr17:24,837,093...24,917,310 		JBrowse link
G RHOT2 ras homolog family member T2 involved_in IEA InterPro GO_REF:0000002 Ensembl chr16:682,588...687,861 JBrowse link
G RHOV ras homolog family member V involved_in IEA InterPro GO_REF:0000002 NCBI chr15:19,814,817...19,816,925
Ensembl chr15:38,064,587...38,066,873 		JBrowse link
G RND1 Rho family GTPase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr12:39,882,076...39,890,797
Ensembl chr12:40,760,706...40,769,401 		JBrowse link
G RND2 Rho family GTPase 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr17:14,276,880...14,298,023
Ensembl chr17:14,521,510...14,528,209 		JBrowse link
G RND3 Rho family GTPase 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr2B:9,387,338...9,406,785
Ensembl chr2B:154,810,039...154,832,768 		JBrowse link
G RUFY1 RUN and FYVE domain containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11172003) Ensembl
MGI		 PMID:11172003 GO_REF:0000107 NCBI chr 5:174,699,240...174,760,876
Ensembl chr 5:181,978,601...182,039,332 		JBrowse link
G SH2D3A SH2 domain containing 3A involved_in IEA InterPro GO_REF:0000002 NCBI chr19:5,784,482...5,800,339
Ensembl chr19:6,706,040...6,720,757 		JBrowse link
G SH2D3C SH2 domain containing 3C involved_in IEA InterPro GO_REF:0000002 NCBI chr 9:98,858,018...98,899,661
Ensembl chr 9:127,530,733...127,571,016 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15728722) Ensembl
MGI
InterPro		 PMID:15728722 GO_REF:0000002 GO_REF:0000107 NCBI chr2A:39,019,046...39,162,248
Ensembl chr2A:39,773,760...39,911,961 		JBrowse link
G SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15728722) Ensembl
MGI
InterPro		 PMID:15728722 GO_REF:0000002 GO_REF:0000107 NCBI chr14:30,707,477...30,822,029
Ensembl chr14:49,014,782...49,101,764 		JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12525493) InterPro
MGI
TreeGrafter		 PMID:12525493 GO_REF:0000002 GO_REF:0000118 NCBI chr21:17,483,273...17,925,301
Ensembl chr21:30,868,308...31,016,883 		JBrowse link
G TIAM2 TIAM Rac1 associated GEF 2 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 6:152,809,716...153,074,427
Ensembl chr 6:158,902,783...159,038,777 		JBrowse link
G USO1 USO1 vesicle transport factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15800058) Ensembl
MGI		 PMID:15800058 GO_REF:0000107 NCBI chr 4:48,391,293...48,480,909
Ensembl chr 4:54,229,601...54,317,158 		JBrowse link
G VAV2 vav guanine nucleotide exchange factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15728722) Ensembl
MGI		 PMID:15728722 GO_REF:0000107 NCBI chr 9:104,883,197...105,115,143
Ensembl chr 9:133,494,481...133,668,036 		JBrowse link
G VAV3 vav guanine nucleotide exchange factor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15728722) Ensembl
MGI		 PMID:15728722 GO_REF:0000107 NCBI chr 1:110,101,651...110,531,294
Ensembl chr 1:109,210,813...109,617,658 		JBrowse link
G YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta acts_upstream_of_or_within ISO (PMID:9211421) MGI PMID:9211421 NCBI chr2A:9,573,413...9,620,495 JBrowse link
ARF protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYO9B myosin IXB NOT|involved_in ISO (PMID:15644318) UniProt PMID:15644318 NCBI chr19:16,563,005...16,700,312 JBrowse link
Cdc42 protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC42 cell division cycle 42 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:21,245,970...21,286,210 JBrowse link
G LOC100993131 cell division control protein 42 homolog involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:33,260,425...33,262,300 JBrowse link
G NTN1 netrin 1 involved_in ISO PMID:23453953 UniProt PMID:23453953 RGD:10054078 NCBI chr17:42,409,797...42,631,930
Ensembl chr17:47,152,225...47,368,134 		JBrowse link
G RHOJ ras homolog family member J involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:43,783,185...43,872,000
Ensembl chr14:62,039,418...62,126,908 		JBrowse link
G RHOV ras homolog family member V involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:19,814,817...19,816,925
Ensembl chr15:38,064,587...38,066,873 		JBrowse link
G SHTN1 shootin 1 involved_in ISO PMID:23453953 UniProt PMID:23453953 RGD:10054078 NCBI chr10:113,466,218...113,587,490
Ensembl chr10:116,896,155...117,016,223 		JBrowse link
G WAS WASP actin nucleation promoting factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:40,982,132...40,989,767
Ensembl chr  X:48,842,765...48,850,380 		JBrowse link
negative regulation of ARF protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GIT1 GIT ArfGAP 1 ISO RGD PMID:16439353 RGD:11344921 NCBI chr17:27,185,025...27,201,146
Ensembl chr17:27,706,776...27,717,857 		JBrowse link
negative regulation of Rac protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARHGAP24 Rho GTPase activating protein 24 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21911940) TreeGrafter
MGI		 PMID:21911940 GO_REF:0000118 NCBI chr 4:77,788,074...78,316,357
Ensembl chr 4:88,619,296...89,045,861 		JBrowse link
G ARHGAP44 Rho GTPase activating protein 44 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:38,657,824...38,859,591
Ensembl chr17:43,357,438...43,453,457 		JBrowse link
G NF1 neurofibromin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15665300) Ensembl
MGI		 PMID:15665300 GO_REF:0000107 NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295 		JBrowse link
G STMN3 stathmin 3 involved_in ISO (MGI:3706230|PMID:17135267) HGNC-UCL PMID:17135267 MGI:3706230
negative regulation of Ras protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAB2IP DAB2 interacting protein ISO RGD PMID:11812785 RGD:632628 NCBI chr 9:92,696,798...92,912,425
Ensembl chr 9:121,143,457...121,254,336 		JBrowse link
G DGKZ diacylglycerol kinase zeta acts_upstream_of_or_within ISO (PMID:15894621) MGI PMID:15894621 NCBI chr11:46,291,592...46,339,127
Ensembl chr11:46,841,605...46,889,763 		JBrowse link
G EPHB2 EPH receptor B2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:21,895,961...22,107,649
Ensembl chr 1:22,912,570...23,047,118 		JBrowse link
G FBP1 fructose-bisphosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:65,695,082...65,731,628
Ensembl chr 9:93,825,150...93,860,968 		JBrowse link
G LOC100993573 rab5 GDP/GTP exchange factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15235600) Ensembl
MGI		 PMID:15235600 GO_REF:0000107 NCBI chr 7:59,268,053...59,344,555
Ensembl chr 7:73,775,002...73,850,446 		JBrowse link
G LZTR1 leucine zipper like post translational regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:3,206,019...3,223,050
Ensembl chr22:19,695,228...19,713,007 		JBrowse link
G MAPKAP1 MAPK associated protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:96,561,157...96,825,478
Ensembl chr 9:125,072,137...125,336,658 		JBrowse link
G MFN2 mitofusin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:10,729,933...10,764,865
Ensembl chr 1:11,945,880...11,981,077 		JBrowse link
G NF1 neurofibromin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11246230), (PMID:15944386)
(PMID:17053831)
(PMID:15665300)
(PMID:16835260), (PMID:16893911)		 Ensembl
MGI		 PMID:11246230 PMID:15665300 PMID:15944386 PMID:16835260 PMID:16893911 More... GO_REF:0000107 NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295 		JBrowse link
G NUP62 nucleoporin 62 involved_in ISO (MGI:3526674|PMID:11489947) UniProt PMID:11489947 MGI:3526674 NCBI chr19:46,919,731...46,942,318 JBrowse link
G PPP2CB protein phosphatase 2 catalytic subunit beta ISO RGD PMID:11884620 RGD:729591 NCBI chr 8:30,099,605...30,126,917
Ensembl chr 8:27,288,263...27,302,606 		JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16858399) Ensembl
MGI		 PMID:16858399 GO_REF:0000107 NCBI chr 9:102,698,970...102,861,482
Ensembl chr 9:131,337,001...131,495,664 		JBrowse link
G RASA2 RAS p21 protein activator 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 3:138,520,013...138,648,798
Ensembl chr 3:146,108,019...146,245,637 		JBrowse link
G RASA3 RAS p21 protein activator 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr13:95,036,382...95,195,480
Ensembl chr13:114,123,816...114,271,066 		JBrowse link
G RASAL1 RAS protein activator like 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr12:110,703,420...110,741,025
Ensembl chr12:114,087,715...114,124,540 		JBrowse link
G RASAL3 RAS protein activator like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:14,982,964...14,995,889
Ensembl chr19:15,969,582...15,981,800 		JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11585837) Ensembl
MGI
TreeGrafter		 PMID:11585837 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:115,570,788...115,578,824
Ensembl chr 4:126,718,811...126,719,770 		JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11585837) Ensembl
MGI
TreeGrafter		 PMID:11585837 GO_REF:0000107 GO_REF:0000118 NCBI chr13:61,569,658...61,574,817
Ensembl chr13:80,596,346...80,597,408 		JBrowse link
G SPRY3 sprouty RTK signaling antagonist 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:145,080,299...145,239,922
Ensembl chr  X:155,131,596...155,132,462 		JBrowse link
G SPRY4 sprouty RTK signaling antagonist 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:137,667,280...137,683,578
Ensembl chr 5:143,778,785...143,791,939 		JBrowse link
G STAMBP STAM binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:73,900,128...73,936,571
Ensembl chr2A:75,410,434...75,451,086 		JBrowse link
G SYNGAP1 synaptic Ras GTPase activating protein 1 involved_in ISO
IEA		 RGD
InterPro		 PMID:21382555 GO_REF:0000002 RGD:7241548 NCBI chr 6:32,999,408...33,033,067
Ensembl chr 6:34,110,652...34,144,490 		JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in ISO (MGI:3830400|PMID:19161227) BHF-UCL PMID:19161227 MGI:3830400 NCBI chr 1:193,907,398...194,005,800
Ensembl chr 1:198,758,751...198,859,041 		JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 ISO RGD PMID:15901773 RGD:1598578 NCBI chr17:72,928,692...73,001,892
Ensembl chr17:78,476,807...78,495,649 		JBrowse link
G TNK1 tyrosine kinase non receptor 1 involved_in ISO (MGI:2664463|PMID:12789265) UniProt PMID:12789265 MGI:2664463 NCBI chr17:7,403,403...7,423,942
Ensembl chr17:7,403,209...7,409,366 		JBrowse link
G TRIM67 tripartite motif containing 67 acts_upstream_of_or_within ISO (PMID:22337885) MGI PMID:22337885 NCBI chr 1:206,710,490...206,770,111 JBrowse link
negative regulation of Rho protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:23595732)
(PMID:22357865)
(PMID:15084284)		 MGI PMID:15084284 PMID:22357865 PMID:23595732 NCBI chr 1:154,586,423...154,711,621
Ensembl chr 1:158,280,994...158,313,915 		JBrowse link
G ADRA1A adrenoceptor alpha 1A acts_upstream_of_or_within ISO PMID:18332105 MGI PMID:18332105 RGD:8554725 NCBI chr 8:25,947,996...26,138,022
Ensembl chr 8:22,853,677...23,044,388 		JBrowse link
G ADRA1B adrenoceptor alpha 1B acts_upstream_of_or_within ISO PMID:18332105 MGI PMID:18332105 RGD:8554725 NCBI chr 5:155,307,148...155,363,785
Ensembl chr 5:161,923,895...161,979,461 		JBrowse link
G ARHGAP35 Rho GTPase activating protein 35 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15084284)
(PMID:23595732)
(PMID:22357865)		 Ensembl
MGI		 PMID:15084284 PMID:22357865 PMID:23595732 GO_REF:0000107 NCBI chr19:43,850,692...43,994,487
Ensembl chr19:52,435,379...52,521,104 		JBrowse link
G ARHGAP42 Rho GTPase activating protein 42 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24335996) Ensembl
MGI		 PMID:24335996 GO_REF:0000107 NCBI chr11:95,655,874...95,962,003
Ensembl chr11:99,159,634...99,460,060 		JBrowse link
G BCL6 BCL6 transcription repressor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15860730) Ensembl
MGI		 PMID:15860730 GO_REF:0000107 NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124 		JBrowse link
G CCDC125 coiled-coil domain containing 125 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:44,667,688...44,717,872
Ensembl chr 5:46,251,209...46,287,598 		JBrowse link
G CUL3 cullin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:111,714,533...111,827,080
Ensembl chr2B:230,289,195...230,378,991 		JBrowse link
G DLC1 DLC1 Rho GTPase activating protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:12,282,190...12,809,770
Ensembl chr 8:9,037,742...9,460,233 		JBrowse link
G FLCN folliculin involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:34,057,127...34,081,637
Ensembl chr17:38,988,518...39,013,160 		JBrowse link
G HEG1 heart development protein with EGF like domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:122,091,832...122,204,436
Ensembl chr 3:128,969,817...129,028,317 		JBrowse link
G ITGA3 integrin subunit alpha 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23595732) Ensembl
MGI		 PMID:23595732 GO_REF:0000107 NCBI chr17:44,145,974...44,181,343
Ensembl chr17:49,019,892...49,055,245 		JBrowse link
G ITGB1 integrin subunit beta 1 acts_upstream_of_or_within ISO (PMID:22357865) MGI PMID:22357865 NCBI chr10:33,023,573...33,081,384
Ensembl chr10:33,608,978...33,644,031 		JBrowse link
G KANK1 KN motif and ankyrin repeat domains 1 involved_in ISO (PMID:18458160) UniProt PMID:18458160 NCBI chr 9:550,713...556,230 JBrowse link
G KCTD10 potassium channel tetramerization domain containing 10 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:107,025,380...107,054,118
Ensembl chr12:110,419,859...110,448,773 		JBrowse link
G KCTD13 potassium channel tetramerization domain containing 13 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118
G LOC100981597 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:43,451,160...43,452,331 JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:108,646,278...108,772,238
Ensembl chr 7:121,365,438...121,468,159 		JBrowse link
G MYOC myocilin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:147,128,541...147,146,227
Ensembl chr 1:150,841,630...150,858,628 		JBrowse link
G RASIP1 Ras interacting protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:45,720,179...45,740,131 JBrowse link
G RIPOR1 RHO family interacting cell polarization regulator 1 involved_in ISO (PMID:25588844) UniProt PMID:25588844 NCBI chr16:47,872,769...47,890,776
Ensembl chr16:67,268,180...67,278,445 		JBrowse link
G RIPOR2 RHO family interacting cell polarization regulator 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:24,642,239...24,768,074
Ensembl chr 6:24,973,412...25,204,745 		JBrowse link
G SCAI suppressor of cancer cell invasion involved_in IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107 NCBI chr 9:96,063,149...96,264,502
Ensembl chr 9:124,589,616...124,780,072 		JBrowse link
G STMN1 stathmin 1 involved_in ISO (PMID:25198505) CAFA PMID:25198505 NCBI chr 1:25,159,241...25,165,535
Ensembl chr 1:26,208,731...26,230,925 		JBrowse link
G TNFAIP1 TNF alpha induced protein 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:28,427,448...28,438,826
Ensembl chr17:28,929,788...28,941,278 		JBrowse link
G TNS3 tensin 3 acts_upstream_of_or_within ISO (PMID:27505886) MGI PMID:27505886 NCBI chr 7:47,915,668...48,223,267
Ensembl chr 7:48,025,720...48,221,437 		JBrowse link
negative regulation of small GTPase mediated signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARHGAP12 Rho GTPase activating protein 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:31,932,294...32,061,450
Ensembl chr10:32,527,838...32,628,690 		JBrowse link
G ARHGAP25 Rho GTPase activating protein 25 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr2A:68,775,637...68,867,870
Ensembl chr2A:69,897,974...69,989,955 		JBrowse link
G CD2AP CD2 associated protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:47,065,284...47,210,746
Ensembl chr 6:48,328,863...48,474,163 		JBrowse link
G CGNL1 cingulin like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:36,344,222...36,518,235
Ensembl chr15:54,669,190...54,831,595 		JBrowse link
G CYRIB CYFIP related Rac1 interactor B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:126,478,020...126,653,936
Ensembl chr 8:129,209,655...129,272,844 		JBrowse link
G LOC100968722 chronophin involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:18,552,737...18,585,014
Ensembl chr22:36,391,200...36,407,938 		JBrowse link
G SLIT2 slit guidance ligand 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:14,654,448...15,023,708
Ensembl chr 4:20,158,952...20,314,656 		JBrowse link
positive regulation of ARF protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 involved_in ISO (MGI:6189265|PMID:25490267) ARUK-UCL PMID:25490267 MGI:6189265 Ensembl chr2A:102,750,221...102,945,263 JBrowse link
G MAPRE2 microtubule associated protein RP/EB family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:28,201,711...28,367,813
Ensembl chr18:31,817,015...31,956,771 		JBrowse link
positive regulation of Rac protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGRN agrin involved_in ISO (PMID:14622576)
(PMID:8653787)		 MGI PMID:8653787 PMID:14622576 Ensembl chr 1:936,000...966,808 JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:23389627) AgBase PMID:23389627 NCBI chr 1:131,282,514...131,326,535
Ensembl chr 1:135,112,040...135,159,299 		JBrowse link
G AUTS2 activator of transcription and developmental regulator AUTS2 involved_in ISO (MGI:5908783|PMID:25533347) UniProt PMID:25533347 MGI:5908783 NCBI chr 7:64,822,964...66,015,831
Ensembl chr 7:77,495,909...78,686,763 		JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta ISO RGD PMID:18385282 RGD:6907067 NCBI chr 4:105,957,773...106,271,887
Ensembl chr 4:116,523,850...116,835,387 		JBrowse link
G CRK CRK proto-oncogene, adaptor protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:1,406,335...1,438,587
Ensembl chr17:1,306,509...1,336,569 		JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:3,141,147...3,177,448
Ensembl chr22:19,632,359...19,668,858 		JBrowse link
G DOK7 docking protein 7 involved_in ISO (PMID:16794080)
(PMID:16794080), (PMID:21041412)		 MGI PMID:16794080 PMID:21041412 NCBI chr 4:3,613,018...3,653,764
Ensembl chr 4:3,605,185...3,628,570 		JBrowse link
G DYNLT1 dynein light chain Tctex-type 1 ISO RGD PMID:15992542 RGD:8553295 NCBI chr 6:156,530,068...156,538,346 JBrowse link
G FNTA farnesyltransferase, CAAX box, subunit alpha involved_in ISO (PMID:14622576) MGI PMID:14622576 NCBI chr 8:42,303,987...42,333,743
Ensembl chr 8:39,743,768...39,774,031 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15665300) Ensembl
MGI		 PMID:15665300 GO_REF:0000107 NCBI chr12:61,062,689...61,108,524
Ensembl chr12:63,679,293...63,724,335 		JBrowse link
G LRP4 LDL receptor related protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:46,808,090...46,868,649
Ensembl chr11:47,366,321...47,411,105 		JBrowse link
G MUSK muscle associated receptor tyrosine kinase involved_in ISO (PMID:8653787)
(PMID:16794080)
(PMID:14622576)		 MGI PMID:8653787 PMID:14622576 PMID:16794080 NCBI chr 9:81,814,766...81,947,341
Ensembl chr 9:109,980,748...110,107,480 		JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:135,685,120...135,867,096
Ensembl chr 3:143,288,563...143,431,314 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:98,841,974...98,885,446
Ensembl chr 7:111,570,148...111,611,614 		JBrowse link
G RTN4 reticulon 4 involved_in ISO (MGI:4366092|PMID:19805174) UniProt PMID:19805174 MGI:4366092 NCBI chr2A:55,129,272...55,207,031 JBrowse link
G TEK TEK receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:26,955,339...27,077,809
Ensembl chr 9:27,561,421...27,683,572 		JBrowse link
G TNS3 tensin 3 acts_upstream_of_or_within ISO (PMID:27505886) MGI PMID:27505886 NCBI chr 7:47,915,668...48,223,267
Ensembl chr 7:48,025,720...48,221,437 		JBrowse link
positive regulation of Ras protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARPP19 cAMP regulated phosphoprotein 19 ISO RGD PMID:12221279 RGD:625586 NCBI chr15:31,488,156...31,510,404
Ensembl chr15:49,813,447...49,835,051 		JBrowse link
G CSF1 colony stimulating factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17053831) Ensembl
MGI		 PMID:17053831 GO_REF:0000107 NCBI chr 1:112,555,755...112,575,894
Ensembl chr 1:127,764,916...127,781,943 		JBrowse link
G DGKI diacylglycerol kinase iota involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15894621) Ensembl
MGI		 PMID:15894621 GO_REF:0000107 NCBI chr 7:129,339,330...129,812,443
Ensembl chr 7:141,841,852...142,142,310 		JBrowse link
G EPO erythropoietin involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:92,747,671...92,750,886
Ensembl chr 7:106,148,062...106,150,974 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO RGD PMID:12673197 RGD:1582125 NCBI chr17:17,560,337...17,600,808
Ensembl chr17:17,777,434...17,805,862 		JBrowse link
G FGF10 fibroblast growth factor 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:65,979,443...66,069,314
Ensembl chr 5:71,028,187...71,111,706 		JBrowse link
G HRAS HRas proto-oncogene, GTPase acts_upstream_of_or_within ISO PMID:19029245 MGI PMID:19029245 RGD:8553977 NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078 		JBrowse link
G IGF1 insulin like growth factor 1 involved_in ISO (PMID:9722506) BHF-UCL PMID:9722506 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177 		JBrowse link
G ITPKB inositol-trisphosphate 3-kinase B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15064401) Ensembl
MGI		 PMID:15064401 GO_REF:0000107 NCBI chr 1:202,091,263...202,198,880
Ensembl chr 1:207,084,883...207,191,678 		JBrowse link
G KITLG KIT ligand involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11435472) Ensembl
MGI		 PMID:11435472 GO_REF:0000107 NCBI chr12:86,036,501...86,124,274
Ensembl chr12:89,341,921...89,436,758 		JBrowse link
G LOC100989926 uncharacterized LOC100989926 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:31,666,381...31,667,410
Ensembl chr 6:32,519,252...32,526,782 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 acts_upstream_of_or_within ISO PMID:19029245 MGI PMID:19029245 RGD:8553977 NCBI chr15:45,337,117...45,438,826
Ensembl chr15:63,613,961...63,714,161 		JBrowse link
G MMD2 monocyte to macrophage differentiation associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:5,158,990...5,218,068
Ensembl chr 7:5,194,496...5,246,234 		JBrowse link
G NGF nerve growth factor involved_in ISO (MGI:2179663|PMID:11877426) ParkinsonsUK-UCL PMID:11877426 MGI:2179663 NCBI chr 1:87,223,597...87,276,759 JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740 		JBrowse link
G NOTCH2 notch receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:82,457,829...82,615,142
Ensembl chr 1:117,538,243...117,612,840 		JBrowse link
G NRG1 neuregulin 1 acts_upstream_of_or_within ISO (PMID:8707830) MGI PMID:8707830 NCBI chr 8:30,954,852...32,084,411
Ensembl chr 8:29,050,222...29,263,977 		JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 involved_in
NOT|involved_in		 IEA
ISO		 (PMID:15488758) Ensembl
UniProt		 PMID:15488758 GO_REF:0000107 Ensembl chr 1:136,007,476...136,047,355 JBrowse link
G PICALM phosphatidylinositol binding clathrin assembly protein involved_in ISO (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chr11:81,011,324...81,122,352
Ensembl chr11:84,619,241...84,730,684 		JBrowse link
G RASGEF1A RasGEF domain family member 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:40,168,940...40,241,547
Ensembl chr10:43,351,953...43,386,875 		JBrowse link
G RASGRF1 Ras protein specific guanine nucleotide releasing factor 1 involved_in ISO PMID:21382555 UniProt PMID:21382555 RGD:7241548 NCBI chr15:57,933,152...58,063,824
Ensembl chr15:76,891,556...77,022,534 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:17,417,684...17,494,333
Ensembl chr15:35,675,348...35,750,315 		JBrowse link
G RASGRP4 RAS guanyl releasing protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:35,503,314...35,520,787
Ensembl chr19:44,074,039...44,091,623 		JBrowse link
G SHOC2 SHOC2 leucine rich repeat scaffold protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:107,512,795...107,606,627
Ensembl chr10:110,993,556...111,055,312 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:8626602 RGD:150523772 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634 		JBrowse link
G STK19 serine/threonine kinase 19 involved_in ISO (PMID:30712867) UniProt PMID:30712867
positive regulation of Rho protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABRA actin binding Rho activating protein involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:103,399,433...103,410,184
Ensembl chr 8:105,546,026...105,556,777 		JBrowse link
G ADGRG1 adhesion G protein-coupled receptor G1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:37,896,177...37,942,040
Ensembl chr16:57,036,425...57,074,221 		JBrowse link
G AKAP13 A-kinase anchoring protein 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:64,076,422...64,438,109
Ensembl chr15:83,387,667...83,651,362 		JBrowse link
G APOA1 apolipoprotein A1 involved_in ISO (PMID:23726972) UniProt PMID:23726972 NCBI chr11:111,673,539...111,675,428
Ensembl chr11:115,606,136...115,608,122 		JBrowse link
G ARHGEF3 Rho guanine nucleotide exchange factor 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:56,663,382...57,012,955
Ensembl chr 3:57,878,054...58,179,339 		JBrowse link
G ARRB1 arrestin beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:70,319,935...70,411,276
Ensembl chr11:73,630,276...73,654,155 		JBrowse link
G COL3A1 collagen type III alpha 1 chain involved_in ISO (MGI:5288127|PMID:21768377) UniProt PMID:21768377 MGI:5288127 NCBI chr2B:76,285,115...76,322,703
Ensembl chr2B:194,204,613...194,242,956 		JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:144,919,775...144,977,105
Ensembl chr 5:150,929,420...150,985,912 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:17,560,337...17,600,808
Ensembl chr17:17,777,434...17,805,862 		JBrowse link
G F11R F11 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:136,399,766...136,424,722
Ensembl chr 1:140,324,943...140,346,890 		JBrowse link
G F2R coagulation factor II thrombin receptor involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:38,462,521...38,478,882
Ensembl chr 5:39,110,170...39,129,688
Ensembl chr 5:39,110,170...39,129,688 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118
G F2RL2 coagulation factor II thrombin receptor like 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:38,680,372...38,688,509
Ensembl chr 5:39,297,424...39,305,370 		JBrowse link
G F2RL3 F2R like thrombin or trypsin receptor 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:16,375,572...16,379,587
Ensembl chr19:17,355,542...17,357,628 		JBrowse link
G GPR17 G protein-coupled receptor 17 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2B:32,623,444...32,630,256
Ensembl chr2B:128,316,464...128,321,519 		JBrowse link
G GPR174 G protein-coupled receptor 174 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:68,284,983...68,286,466
Ensembl chr  X:78,395,005...78,396,006 		JBrowse link
G GPR18 G protein-coupled receptor 18 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:80,423,534...80,427,604
Ensembl chr13:99,562,589...99,563,584 		JBrowse link
G GPR20 G protein-coupled receptor 20 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:138,024,139...138,037,886
Ensembl chr 8:141,108,910...141,109,986 		JBrowse link
G GPR35 G protein-coupled receptor 35 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2B:127,853,660...127,887,204
Ensembl chr2B:246,680,998...246,692,090 		JBrowse link
G GPR4 G protein-coupled receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:42,594,996...42,608,032
Ensembl chr19:51,137,138...51,138,226 		JBrowse link
G GPR55 G protein-coupled receptor 55 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr2B:118,159,511...118,163,334
Ensembl chr2B:236,958,210...236,959,169 		JBrowse link
G ITSN1 intersectin 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:20,009,385...20,266,835
Ensembl chr21:33,457,081...33,625,248 		JBrowse link
G ITSN2 intersectin 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2A:24,199,600...24,354,314
Ensembl chr2A:24,297,373...24,419,593 		JBrowse link
G LPAR1 lysophosphatidic acid receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15755723) Ensembl
MGI		 PMID:15755723 GO_REF:0000107 NCBI chr 9:82,013,960...82,179,227
Ensembl chr 9:110,179,600...110,279,038 		JBrowse link
G LPAR2 lysophosphatidic acid receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15755723) Ensembl
MGI		 PMID:15755723 GO_REF:0000107 NCBI chr19:19,060,927...19,065,792
Ensembl chr19:20,057,179...20,061,260 		JBrowse link
G LPAR6 lysophosphatidic acid receptor 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:29,561,219...29,567,414
Ensembl chr13:48,263,254...48,264,291 		JBrowse link
G MCF2L MCF.2 cell line derived transforming sequence like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:94,024,030...94,239,491
Ensembl chr13:113,111,066...113,309,224 		JBrowse link
G NET1 neuroepithelial cell transforming 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:5,457,920...5,503,223
Ensembl chr10:5,444,127...5,489,509 		JBrowse link
G NGFR nerve growth factor receptor ISO RGD PMID:18786176 RGD:5508741 NCBI chr17:8,089,600...8,109,361
Ensembl chr17:8,075,316...8,094,966 		JBrowse link
G P2RY8 P2Y receptor family member 8 involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr  X:1,599,411...1,600,490 JBrowse link
G PDGFRB platelet derived growth factor receptor beta ISO RGD PMID:18561944 RGD:10449505 NCBI chr 5:145,538,330...145,580,312
Ensembl chr 5:151,543,891...151,585,530 		JBrowse link
G PLXNB1 plexin B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:48,325,892...48,352,128
Ensembl chr 3:49,408,666...49,434,913 		JBrowse link
G PRAG1 PEAK1 related, kinase-activating pseudokinase 1 involved_in ISO PMID:16481321 UniProt PMID:16481321 RGD:11555369 NCBI chr 8:10,824,887...10,896,058 JBrowse link
G ROBO1 roundabout guidance receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:78,707,802...79,876,519
Ensembl chr 3:80,581,388...81,569,308 		JBrowse link
G RTN4R reticulon 4 receptor involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 Ensembl chr22:18,673,548...18,680,017 JBrowse link
G SEMA4D semaphorin 4D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:60,451,420...60,588,519
Ensembl chr 9:88,497,528...88,560,811 		JBrowse link
G SYNPO2L synaptopodin 2 like involved_in ISO (MGI:6102963|PMID:29206857) BHF-UCL PMID:29206857 MGI:6102963 NCBI chr10:70,192,289...70,204,008
Ensembl chr10:72,648,952...72,660,184 		JBrowse link
G TEK TEK receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:26,955,339...27,077,809
Ensembl chr 9:27,561,421...27,683,572 		JBrowse link
positive regulation of small GTPase mediated signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCYAP1R1 ADCYAP receptor type I involved_in ISO PMID:18541665 ParkinsonsUK-UCL PMID:18541665 RGD:2325271 NCBI chr 7:31,597,251...31,724,299
Ensembl chr 7:31,784,622...31,843,381 		JBrowse link
G BNIP2 BCL2 interacting protein 2 acts_upstream_of_or_within ISO (PMID:19244314) MGI PMID:19244314 NCBI chr15:38,628,798...38,659,161
Ensembl chr15:56,933,697...56,964,044 		JBrowse link
G CDON cell adhesion associated, oncogene regulated involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19244314) Ensembl
MGI		 PMID:19244314 GO_REF:0000107 NCBI chr11:120,772,160...120,877,529
Ensembl chr11:124,685,084...124,786,091 		JBrowse link
G FRMD7 FERM domain containing 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23967341) Ensembl
MGI		 PMID:23967341 GO_REF:0000107 NCBI chr  X:121,208,961...121,259,708
Ensembl chr  X:131,516,484...131,567,394 		JBrowse link
G ITGAV integrin subunit alpha V involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:73,880,962...73,972,486
Ensembl chr2B:191,680,655...191,773,028 		JBrowse link
G RELN reelin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15062102) Ensembl
MGI		 PMID:15062102 GO_REF:0000107 NCBI chr 7:95,464,285...95,984,813
Ensembl chr 7:108,208,344...108,728,037 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO RGD PMID:20219970 RGD:5686649 NCBI chr2A:39,019,046...39,162,248
Ensembl chr2A:39,773,760...39,911,961 		JBrowse link
G SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2 ISO RGD PMID:20219970 RGD:5686649 NCBI chr14:30,707,477...30,822,029
Ensembl chr14:49,014,782...49,101,764 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634 		JBrowse link
Rab protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD2AP CD2 associated protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27076424) Ensembl
MGI		 PMID:27076424 GO_REF:0000107 NCBI chr 6:47,065,284...47,210,746
Ensembl chr 6:48,328,863...48,474,163 		JBrowse link
G RAB12 RAB12, member RAS oncogene family involved_in IEA InterPro GO_REF:0000002 NCBI chr18:5,646,023...5,675,920
Ensembl chr18:7,972,938...8,027,500 		JBrowse link
G RAB21 RAB21, member RAS oncogene family involved_in IEA InterPro GO_REF:0000002 NCBI chr12:69,278,191...69,309,143
Ensembl chr12:72,137,432...72,171,844 		JBrowse link
G RAB30 RAB30, member RAS oncogene family involved_in IEA InterPro GO_REF:0000002 NCBI chr11:78,040,163...78,136,785
Ensembl chr11:81,659,732...81,711,750 		JBrowse link
G RAB33A RAB33A, member RAS oncogene family involved_in IEA InterPro GO_REF:0000002 NCBI chr  X:119,298,428...119,311,625
Ensembl chr  X:129,591,222...129,605,214 		JBrowse link
G RAB33B RAB33B, member RAS oncogene family involved_in IEA InterPro GO_REF:0000002 NCBI chr 4:131,815,088...131,838,957
Ensembl chr 4:143,123,478...143,147,147 		JBrowse link
G RAB39A RAB39A, member RAS oncogene family involved_in IEA InterPro GO_REF:0000002 NCBI chr11:102,814,825...102,851,700
Ensembl chr11:106,291,348...106,326,587 		JBrowse link
G RAB39B RAB39B, member RAS oncogene family involved_in IEA InterPro GO_REF:0000002 NCBI chr  X:144,728,535...144,734,893
Ensembl chr  X:154,567,361...154,573,715 		JBrowse link
G RAB4A RAB4A, member RAS oncogene family involved_in ISO
IEA		 RGD
InterPro
UniProt		 PMID:9169411 GO_REF:0000002 GO_REF:0000104 RGD:2306443 NCBI chr 1:204,818,445...204,849,775
Ensembl chr 1:209,848,620...209,883,305 		JBrowse link
G RAB4B RAB4B, member RAS oncogene family involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr19:37,821,564...37,840,257
Ensembl chr19:46,328,788...46,346,492 		JBrowse link
G RAB9A RAB9A, member RAS oncogene family involved_in IEA InterPro GO_REF:0000002 NCBI chr  X:6,296,483...6,317,826
Ensembl chr  X:13,604,454...13,605,059 		JBrowse link
G RAB9B RAB9B, member RAS oncogene family involved_in IEA InterPro GO_REF:0000002 NCBI chr  X:93,060,899...93,070,911
Ensembl chr  X:103,444,776...103,445,381 		JBrowse link
Rac protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI2 abl interactor 2 involved_in ISO (PMID:21107423) UniProt PMID:21107423 NCBI chr2B:90,561,708...90,663,072
Ensembl chr2B:208,702,092...208,797,499 		JBrowse link
G AIF1 allograft inflammatory factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,276,215...31,278,051
Ensembl chr 6:32,166,301...32,168,125 		JBrowse link
G ALS2 alsin Rho guanine nucleotide exchange factor ALS2 ISO RGD PMID:16802292 RGD:1599082 NCBI chr2B:88,954,167...89,034,764
Ensembl chr2B:207,108,952...207,189,623 		JBrowse link
G ARHGAP24 Rho GTPase activating protein 24 acts_upstream_of ISO (PMID:21911940) MGI PMID:21911940 NCBI chr 4:77,788,074...78,316,357
Ensembl chr 4:88,619,296...89,045,861 		JBrowse link
G BRK1 BRICK1 subunit of SCAR/WAVE actin nucleating complex involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:10,051,054...10,062,364
Ensembl chr 3:10,403,896...10,415,545 		JBrowse link
G CDH13 cadherin 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:63,255,482...64,418,053
Ensembl chr16:82,883,184...83,808,996 		JBrowse link
G CYFIP1 cytoplasmic FMR1 interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr15:20,462,811...20,573,684 JBrowse link
G DBNL drebrin like acts_upstream_of_or_within ISO (PMID:10637315) MGI PMID:10637315 NCBI chr 7:44,753,062...44,775,717
Ensembl chr 7:44,824,608...44,845,891 		JBrowse link
G DOCK5 dedicator of cytokinesis 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:24,463,582...24,696,736
Ensembl chr 8:21,372,756...21,605,877 		JBrowse link
G ELMO1 engulfment and cell motility 1 involved_in ISO (PMID:11595183) UniProt PMID:11595183 NCBI chr 7:37,493,854...38,085,555 JBrowse link
G EPS8 EGFR pathway substrate 8, signaling adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:15,617,536...15,788,537
Ensembl chr12:16,013,276...16,076,117 		JBrowse link
G FARP1 FERM, ARH/RhoGEF and pleckstrin domain protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:79,300,995...79,615,649
Ensembl chr13:98,522,235...98,761,085 		JBrowse link
G FARP2 FERM, ARH/RhoGEF and pleckstrin domain protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12351724) MGI
Ensembl		 PMID:12351724 GO_REF:0000107 NCBI chr2B:128,627,208...128,766,233
Ensembl chr2B:247,438,265...247,559,735 		JBrowse link
G GARRE1 granule associated Rac and RHOG effector 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:31,191,349...31,292,232
Ensembl chr19:39,951,290...40,021,261 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase involved_in
acts_upstream_of		 IEA
ISO		 (PMID:15665300) Ensembl
MGI		 PMID:15665300 GO_REF:0000107 NCBI chr12:61,062,689...61,108,524
Ensembl chr12:63,679,293...63,724,335 		JBrowse link
G NCKAP1 NCK associated protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:70,193,950...70,308,442
Ensembl chr2B:188,003,235...188,116,710 		JBrowse link
G NF1 neurofibromin 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:15665300) Ensembl
MGI		 PMID:15665300 GO_REF:0000107 NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295 		JBrowse link
G NISCH nischarin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11121431) Ensembl
MGI		 PMID:11121431 GO_REF:0000107 NCBI chr 3:52,397,576...52,435,127
Ensembl chr 3:53,626,317...53,662,567 		JBrowse link
G RAC1 Rac family small GTPase 1 involved_in ISO PMID:15800193
(PMID:14622576)		 SynGO
MGI		 PMID:14622576 PMID:15800193 RGD:12050102 NCBI chr 7:7,039,379...7,068,866 JBrowse link
G RHOG ras homolog family member G acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12376551) MGI
TreeGrafter
Ensembl		 PMID:12376551 GO_REF:0000107 GO_REF:0000118 NCBI chr11:3,698,179...3,712,402
Ensembl chr11:3,811,877...3,812,452 		JBrowse link
G RHOU ras homolog family member U acts_upstream_of_or_within ISO (PMID:11459829) MGI PMID:11459829 NCBI chr 1:204,282,231...204,293,758 JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:17,483,273...17,925,301
Ensembl chr21:30,868,308...31,016,883 		JBrowse link
G WASF1 WASP family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:107,911,751...107,988,821
Ensembl chr 6:111,951,726...111,979,329 		JBrowse link
G WASF2 WASP family member 2 acts_upstream_of_or_within ISO (PMID:12853475) MGI PMID:12853475 NCBI chr 1:26,665,853...26,750,618
Ensembl chr 1:27,717,538...27,737,316 		JBrowse link
Ral protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NKIRAS1 NFKB inhibitor interacting Ras like 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25220458) Ensembl
MGI
TreeGrafter		 PMID:25220458 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:23,804,054...23,829,071
Ensembl chr 3:24,128,587...24,146,611 		JBrowse link
G NKIRAS2 NFKB inhibitor interacting Ras like 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25220458) Ensembl
MGI
TreeGrafter		 PMID:25220458 GO_REF:0000107 GO_REF:0000118 NCBI chr17:15,290,435...15,299,060
Ensembl chr17:15,509,758...15,518,379 		JBrowse link
G RALGAPA2 Ral GTPase activating protein catalytic subunit alpha 2 acts_upstream_of_or_within ISO (PMID:21148297) MGI PMID:21148297 NCBI chr20:20,338,629...20,662,926
Ensembl chr20:20,299,638...20,625,443 		JBrowse link
G RALGAPB Ral GTPase activating protein non-catalytic subunit beta acts_upstream_of_or_within ISO (PMID:21148297) MGI PMID:21148297 NCBI chr20:34,797,472...34,903,367
Ensembl chr20:35,906,029...36,011,685 		JBrowse link
Rap protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLK2 polo like kinase 2 involved_in ISO PMID:21382555 UniProt PMID:21382555 RGD:7241548 NCBI chr 5:55,543,828...55,550,116
Ensembl chr 5:57,177,836...57,184,793 		JBrowse link
G RAP1A RAP1A, member of RAS oncogene family involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:114,279,255...114,376,977
Ensembl chr 1:125,971,598...125,994,813 		JBrowse link
G RAP1B RAP1B, member of RAS oncogene family involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr12:66,122,212...66,172,450
Ensembl chr12:68,942,053...68,955,649 		JBrowse link
G RAP2A RAP2A, member of RAS oncogene family involved_in IEA InterPro
TreeGrafter
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr13:78,595,330...78,629,012
Ensembl chr13:97,751,799...97,785,194 		JBrowse link
G RAP2B RAP2B, member of RAS oncogene family involved_in IEA UniProt
TreeGrafter
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:150,188,107...150,193,060
Ensembl chr 3:157,754,470...157,755,021 		JBrowse link
G RAP2C RAP2C, member of RAS oncogene family involved_in IEA InterPro
TreeGrafter
UniProt
Ensembl		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:121,334,292...121,350,658
Ensembl chr  X:131,641,193...131,656,447 		JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 involved_in ISO (PMID:21840392) UniProt PMID:21840392 NCBI chr 9:102,698,970...102,861,482
Ensembl chr 9:131,337,001...131,495,664 		JBrowse link
G RAPGEF2 Rap guanine nucleotide exchange factor 2 involved_in ISO (PMID:21840392) UniProt PMID:21840392 NCBI chr 4:151,419,402...151,680,769
Ensembl chr 4:163,316,396...163,487,495 		JBrowse link
G RAPGEF3 Rap guanine nucleotide exchange factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:40,974,756...40,999,471
Ensembl chr12:41,848,785...41,873,252 		JBrowse link
G SGSM3 small G protein signaling modulator 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:21,275,464...21,314,652
Ensembl chr22:39,402,336...39,411,884 		JBrowse link
Ras protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARAF A-Raf proto-oncogene, serine/threonine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:39,997,026...40,007,783
Ensembl chr  X:47,893,153...47,904,643 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:132,651,908...132,855,422
Ensembl chr 7:145,138,510...145,327,115 		JBrowse link
G BRAP BRCA1 associated protein acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:14724641) MGI
TreeGrafter
Ensembl		 PMID:14724641 GO_REF:0000107 GO_REF:0000118 NCBI chr12:109,216,171...109,263,160
Ensembl chr12:112,610,179...112,654,017 		JBrowse link
G CCNA2 cyclin A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:114,016,917...114,024,816
Ensembl chr 4:125,153,810...125,161,302 		JBrowse link
G CDK2 cyclin dependent kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:32,940,225...32,946,236
Ensembl chr12:33,189,934...33,195,945 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in ISO (PMID:9054499) BHF-UCL PMID:9054499 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CSF1 colony stimulating factor 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17053831) Ensembl
MGI		 PMID:17053831 GO_REF:0000107 NCBI chr 1:112,555,755...112,575,894
Ensembl chr 1:127,764,916...127,781,943 		JBrowse link
G DGKI diacylglycerol kinase iota involved_in
acts_upstream_of		 IEA
ISO		 (PMID:15894621) Ensembl
MGI		 PMID:15894621 GO_REF:0000107 NCBI chr 7:129,339,330...129,812,443
Ensembl chr 7:141,841,852...142,142,310 		JBrowse link
G DGKZ diacylglycerol kinase zeta acts_upstream_of ISO (PMID:15894621) MGI PMID:15894621 NCBI chr11:46,291,592...46,339,127
Ensembl chr11:46,841,605...46,889,763 		JBrowse link
G DHCR24 24-dehydrocholesterol reductase ISO RGD PMID:15577914 RGD:1600898 NCBI chr 1:54,126,170...54,163,713
Ensembl chr 1:55,714,693...55,754,698 		JBrowse link
G DOK1 docking protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9008161) TreeGrafter
MGI		 PMID:9008161 GO_REF:0000118 NCBI chr2A:74,615,542...74,624,183
Ensembl chr2A:76,126,749...76,130,162 		JBrowse link
G DOK2 docking protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9697832) Ensembl
MGI
TreeGrafter		 PMID:9697832 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:21,153,653...21,159,863
Ensembl chr 8:18,094,383...18,099,225 		JBrowse link
G DOK3 docking protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10567556) Ensembl
MGI
TreeGrafter		 PMID:10567556 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:172,803,094...172,812,613
Ensembl chr 5:179,864,910...179,874,190 		JBrowse link
G DOK4 docking protein 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:37,748,004...37,762,435
Ensembl chr16:56,880,935...56,888,765 		JBrowse link
G DOK5 docking protein 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:50,821,093...50,996,536
Ensembl chr20:52,042,491...52,217,846 		JBrowse link
G DOK6 docking protein 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr18:62,785,687...63,227,505
Ensembl chr18:66,236,817...66,512,229 		JBrowse link
G ERAS ES cell expressed Ras involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:41,125,895...41,127,757
Ensembl chr  X:48,986,812...48,987,513 		JBrowse link
G HRAS HRas proto-oncogene, GTPase involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:12077341 GO_REF:0000107 GO_REF:0000118 RGD:1358732 NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078 		JBrowse link
G IQGAP3 IQ motif containing GTPase activating protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18604197) Ensembl
MGI		 PMID:18604197 GO_REF:0000107 NCBI chr 1:131,869,002...131,916,554
Ensembl chr 1:135,695,602...135,740,564 		JBrowse link
G KITLG KIT ligand involved_in
acts_upstream_of		 IEA
ISO		 (PMID:11435472) Ensembl
MGI		 PMID:11435472 GO_REF:0000107 NCBI chr12:86,036,501...86,124,274
Ensembl chr12:89,341,921...89,436,758 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15665300)
(PMID:22577135)		 Ensembl
MGI
TreeGrafter		 PMID:15665300 PMID:22577135 GO_REF:0000107 GO_REF:0000118 NCBI chr12:61,062,689...61,108,524
Ensembl chr12:63,679,293...63,724,335 		JBrowse link
G KSR1 kinase suppressor of ras 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:29,148,382...29,316,829
Ensembl chr17:29,649,105...29,720,651 		JBrowse link
G KSR2 kinase suppressor of ras 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:115,038,344...115,548,452
Ensembl chr12:118,420,483...118,925,686 		JBrowse link
G LAT linker for activation of T cells involved_in IEA Ensembl GO_REF:0000107
G LOC100969771 ral-GDS-related protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:4,424,113...4,432,004 JBrowse link
G LOC100993573 rab5 GDP/GTP exchange factor involved_in
acts_upstream_of		 IEA
ISO		 (PMID:15235600) Ensembl
MGI		 PMID:15235600 GO_REF:0000107 NCBI chr 7:59,268,053...59,344,555
Ensembl chr 7:73,775,002...73,850,446 		JBrowse link
G MAPKAPK5 MAPK activated protein kinase 5 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:109,416,610...109,471,729
Ensembl chr12:112,812,769...112,863,595 		JBrowse link
G MRAS muscle RAS oncogene homolog involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:135,377,488...135,435,338
Ensembl chr 3:142,827,020...142,884,582 		JBrowse link
G NF1 neurofibromin 1 involved_in
acts_upstream_of
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11246230), (PMID:15944386)
(PMID:16906226), (PMID:8563750), (PMID:9001241)
(PMID:16835260), (PMID:16893911)
(PMID:15665300)
(PMID:17053831)
(PMID:12469121)
(PMID:10845775)
(PMID:10498620), (PMID:11435472)		 Ensembl
MGI		 PMID:8563750 PMID:9001241 PMID:10498620 PMID:10845775 PMID:11246230 More... GO_REF:0000107 NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:87,837,146...87,850,013
Ensembl chr 1:122,890,505...122,903,585 		JBrowse link
G NTN1 netrin 1 involved_in ISO PMID:23453953 UniProt PMID:23453953 RGD:10054078 NCBI chr17:42,409,797...42,631,930
Ensembl chr17:47,152,225...47,368,134 		JBrowse link
G PLCE1 phospholipase C epsilon 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:11179219 GO_REF:0000107 RGD:68714 NCBI chr10:90,731,695...91,065,846
Ensembl chr10:94,278,550...94,575,024 		JBrowse link
G PLK2 polo like kinase 2 involved_in ISO PMID:21382555 UniProt PMID:21382555 RGD:7241548 NCBI chr 5:55,543,828...55,550,116
Ensembl chr 5:57,177,836...57,184,793 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:12,510,084...12,590,598
Ensembl chr 3:12,853,415...12,932,871 		JBrowse link
G RALA RAS like proto-oncogene A involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:44,528,146...44,611,431
Ensembl chr 7:44,559,380...44,580,495 		JBrowse link
G RALB RAS like proto-oncogene B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2B:7,185,192...7,227,220
Ensembl chr2B:120,748,123...120,802,698 		JBrowse link
G RALGDS ral guanine nucleotide dissociation stimulator involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:104,218,338...104,269,322
Ensembl chr 9:132,832,924...132,865,901 		JBrowse link
G RALGPS1 Ral GEF with PH domain and SH3 binding motif 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:98,033,100...98,342,582
Ensembl chr 9:126,689,557...126,992,628 		JBrowse link
G RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:154,224,362...154,411,202
Ensembl chr 1:157,916,856...158,097,550 		JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16858399) Ensembl
MGI
TreeGrafter		 PMID:16858399 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:102,698,970...102,861,482
Ensembl chr 9:131,337,001...131,495,664 		JBrowse link
G RAPGEF3 Rap guanine nucleotide exchange factor 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:40,974,756...40,999,471
Ensembl chr12:41,848,785...41,873,252 		JBrowse link
G RAPGEF4 Rap guanine nucleotide exchange factor 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2B:60,022,738...60,339,981
Ensembl chr2B:177,655,733...177,793,644 		JBrowse link
G RAPGEF5 Rap guanine nucleotide exchange factor 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:22,806,855...23,047,663
Ensembl chr 7:22,122,434...22,317,650 		JBrowse link
G RAPGEFL1 Rap guanine nucleotide exchange factor like 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:17,093,714...17,111,187
Ensembl chr17:17,315,114...17,335,258 		JBrowse link
G RASGEF1A RasGEF domain family member 1A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:40,168,940...40,241,547
Ensembl chr10:43,351,953...43,386,875 		JBrowse link
G RASGEF1B RasGEF domain family member 1B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:42,153,818...42,771,749
Ensembl chr 4:48,004,253...48,620,978 		JBrowse link
G RASGEF1C RasGEF domain family member 1C involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:175,277,643...175,313,874 JBrowse link
G RASGRF1 Ras protein specific guanine nucleotide releasing factor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:57,933,152...58,063,824
Ensembl chr15:76,891,556...77,022,534 		JBrowse link
G RASGRF2 Ras protein specific guanine nucleotide releasing factor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:34,048,832...34,326,755
Ensembl chr 5:34,359,896...34,635,488 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:17,417,684...17,494,333
Ensembl chr15:35,675,348...35,750,315 		JBrowse link
G RASGRP2 RAS guanyl releasing protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:60,081,781...60,101,400
Ensembl chr11:63,423,112...63,440,917 		JBrowse link
G RASGRP3 RAS guanyl releasing protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15545601) Ensembl
MGI
TreeGrafter		 PMID:15545601 GO_REF:0000107 GO_REF:0000118 NCBI chr2A:33,444,941...33,572,829
Ensembl chr2A:34,196,421...34,284,307 		JBrowse link
G RASGRP4 RAS guanyl releasing protein 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:35,503,314...35,520,787
Ensembl chr19:44,074,039...44,091,623 		JBrowse link
G RASSF1 Ras association domain family member 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:50,255,897...50,267,042
Ensembl chr 3:51,491,548...51,502,392 		JBrowse link
G RB1 RB transcriptional corepressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:29,453,872...29,624,665
Ensembl chr13:48,155,795...48,324,575 		JBrowse link
G RFXANK regulatory factor X associated ankyrin containing protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10329666) Ensembl
MGI		 PMID:10329666 GO_REF:0000107 NCBI chr19:18,630,221...18,639,840
Ensembl chr19:19,631,847...19,640,619 		JBrowse link
G RGL1 ral guanine nucleotide dissociation stimulator like 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:159,166,090...159,457,883
Ensembl chr 1:163,429,258...163,614,657 		JBrowse link
G RGL2 ral guanine nucleotide dissociation stimulator like 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:32,863,954...32,871,684
Ensembl chr 6:33,978,024...33,985,749 		JBrowse link
G RGL3 ral guanine nucleotide dissociation stimulator like 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:10,932,016...10,966,701
Ensembl chr19:11,652,700...11,685,293 		JBrowse link
G RIT1 Ras like without CAAX 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:131,232,277...131,245,437
Ensembl chr 1:135,063,000...135,074,942 		JBrowse link
G RIT2 Ras like without CAAX 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:36,008,302...36,381,259
Ensembl chr18:39,557,814...39,930,393 		JBrowse link
G RRAS RAS related involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:46,649,892...46,654,754
Ensembl chr19:55,569,749...55,573,721 		JBrowse link
G RRAS2 RAS related 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11788587) TreeGrafter
MGI		 PMID:11788587 GO_REF:0000118 NCBI chr11:14,381,173...14,462,192
Ensembl chr11:14,073,679...14,159,611 		JBrowse link
G RSU1 Ras suppressor protein 1 acts_upstream_of_or_within ISO (PMID:1508180) MGI PMID:1508180 NCBI chr10:16,909,912...17,134,697
Ensembl chr10:17,184,511...17,407,769 		JBrowse link
G SDCBP syndecan binding protein acts_upstream_of_or_within ISO (PMID:15014045) MGI PMID:15014045 NCBI chr 8:54,992,627...55,022,560
Ensembl chr 8:56,643,962...56,673,833 		JBrowse link
G SHTN1 shootin 1 involved_in ISO PMID:23453953 UniProt PMID:23453953 RGD:10054078 NCBI chr10:113,466,218...113,587,490
Ensembl chr10:116,896,155...117,016,223 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:15728722 GO_REF:0000107 GO_REF:0000118 RGD:1581104 NCBI chr2A:39,019,046...39,162,248
Ensembl chr2A:39,773,760...39,911,961 		JBrowse link
G SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:30,707,477...30,822,029
Ensembl chr14:49,014,782...49,101,764 		JBrowse link
G SYNGAP1 synaptic Ras GTPase activating protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15014045) Ensembl
MGI		 PMID:15014045 GO_REF:0000107 NCBI chr 6:32,999,408...33,033,067
Ensembl chr 6:34,110,652...34,144,490 		JBrowse link
G TP53 tumor protein p53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120 		JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 acts_upstream_of_or_within ISO (PMID:15014045) MGI PMID:15014045 NCBI chr12:129,549,399...129,579,087 JBrowse link
G USP50 ubiquitin specific peptidase 50 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:29,450,804...29,500,515
Ensembl chr15:47,790,100...47,839,619 		JBrowse link
G USP8 ubiquitin specific peptidase 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11500497) TreeGrafter
MGI		 PMID:11500497 GO_REF:0000118 NCBI chr15:29,374,945...29,451,235
Ensembl chr15:47,713,997...47,790,624 		JBrowse link
regulation of ARF protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARFGAP1 ADP ribosylation factor GTPase activating protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:59,656,731...59,674,802
Ensembl chr20:61,197,583...61,214,635 		JBrowse link
G ARFGEF1 ADP ribosylation factor guanine nucleotide exchange factor 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 8:63,740,512...63,884,189
Ensembl chr 8:65,403,386...65,545,789 		JBrowse link
G ARFGEF2 ADP ribosylation factor guanine nucleotide exchange factor 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr20:45,262,330...45,376,237
Ensembl chr20:46,327,753...46,442,518 		JBrowse link
G ARFGEF3 ARFGEF family member 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr 6:135,916,799...136,100,287
Ensembl chr 6:140,010,542...140,179,197 		JBrowse link
G CYTH1 cytohesin 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr17:72,749,310...72,857,992
Ensembl chr17:78,295,437...78,358,735 		JBrowse link
G CYTH2 cytohesin 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr19:45,471,277...45,481,350
Ensembl chr19:54,063,560...54,073,017 		JBrowse link
G CYTH3 cytohesin 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:7,170,064...7,283,000
Ensembl chr 7:6,357,978...6,386,756 		JBrowse link
G CYTH4 cytohesin 4 involved_in IEA InterPro GO_REF:0000002 NCBI chr22:18,197,307...18,230,274
Ensembl chr22:36,040,326...36,061,264 		JBrowse link
G FBXO8 F-box protein 8 involved_in IEA InterPro GO_REF:0000002 NCBI chr 4:166,462,626...166,509,875
Ensembl chr 4:178,696,995...178,744,895 		JBrowse link
G GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr10:98,849,000...98,986,443
Ensembl chr10:102,316,329...102,452,439 		JBrowse link
G GIT1 GIT ArfGAP 1 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr17:27,185,025...27,201,146
Ensembl chr17:27,706,776...27,717,857 		JBrowse link
G GIT2 GIT ArfGAP 2 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr12:107,505,791...107,572,641
Ensembl chr12:110,901,303...110,967,489 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:26884337 RGD:11560558 NCBI chr16:8,682,169...9,105,581
Ensembl chr16:9,919,143...10,336,167 		JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:26884337 RGD:11560558 NCBI chr12:13,543,104...13,987,437
Ensembl chr12:13,969,387...14,388,799 		JBrowse link
G IQSEC1 IQ motif and Sec7 domain ArfGEF 1 involved_in IEA
ISO		 InterPro
RGD		 PMID:26884337 GO_REF:0000002 RGD:11560558 NCBI chr 3:12,820,552...13,202,925
Ensembl chr 3:13,167,299...13,235,285 		JBrowse link
G IQSEC2 IQ motif and Sec7 domain ArfGEF 2 involved_in IEA
ISO		 InterPro
RGD		 PMID:26884337 GO_REF:0000002 RGD:11560558 NCBI chr  X:45,447,977...45,535,836
Ensembl chr  X:53,557,563...53,644,737 		JBrowse link
G IQSEC3 IQ motif and Sec7 domain ArfGEF 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr12:128,587...236,302
Ensembl chr12:105,804...209,812 		JBrowse link
G PSD pleckstrin and Sec7 domain containing involved_in IEA InterPro GO_REF:0000002 NCBI chr10:99,006,102...99,023,411
Ensembl chr10:102,472,583...102,486,226 		JBrowse link
G PSD2 pleckstrin and Sec7 domain containing 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:135,162,701...135,211,389
Ensembl chr 5:141,294,395...141,329,952 		JBrowse link
G PSD3 pleckstrin and Sec7 domain containing 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr 8:17,758,287...18,308,876
Ensembl chr 8:14,714,575...15,258,823 		JBrowse link
G PSD4 pleckstrin and Sec7 domain containing 4 involved_in IEA InterPro GO_REF:0000002 NCBI chr2A:88,921,973...88,968,297
Ensembl chr2A:114,125,643...114,145,103 		JBrowse link
regulation of Cdc42 protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:75,948,831...76,096,136
Ensembl chr 9:104,076,516...104,224,188 		JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:101,834,189...102,005,811
Ensembl chr 9:130,484,333...130,652,941 		JBrowse link
G APOA1 apolipoprotein A1 involved_in ISO (PMID:16443932) BHF-UCL PMID:16443932 NCBI chr11:111,673,539...111,675,428
Ensembl chr11:115,606,136...115,608,122 		JBrowse link
G APOC3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:111,667,816...111,670,861
Ensembl chr11:115,600,416...115,603,460 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G NRP1 neuropilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:33,298,918...33,456,466
Ensembl chr10:33,883,173...34,039,648 		JBrowse link
G RALBP1 ralA binding protein 1 involved_in ISO PMID:7623849 UniProt PMID:7623849 RGD:633902 NCBI chr18:4,747,555...4,810,710
Ensembl chr18:7,028,188...7,090,934 		JBrowse link
G RIT2 Ras like without CAAX 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:36,008,302...36,381,259
Ensembl chr18:39,557,814...39,930,393 		JBrowse link
regulation of Rab protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DENND1A DENN domain containing 1A involved_in ISO (PMID:20937701) FlyBase PMID:20937701 NCBI chr 9:94,511,281...95,053,490
Ensembl chr 9:123,037,217...123,532,037 		JBrowse link
G DENND3 DENN domain containing 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:137,805,456...137,873,492
Ensembl chr 8:140,889,343...140,956,967 		JBrowse link
G DENND4A DENN domain containing 4A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:44,600,897...44,734,150
Ensembl chr15:62,882,496...63,012,979 		JBrowse link
G DENND4B DENN domain containing 4B involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:129,286,076...129,303,279
Ensembl chr 1:132,914,514...132,929,906 		JBrowse link
G DENND4C DENN domain containing 4C involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:19,046,857...19,183,364
Ensembl chr 9:19,537,997...19,672,299 		JBrowse link
G MADD MAP kinase activating death domain involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:47,216,006...47,276,422
Ensembl chr11:47,773,733...47,828,360 		JBrowse link
G SGSM3 small G protein signaling modulator 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:21,275,464...21,314,652
Ensembl chr22:39,402,336...39,411,884 		JBrowse link
regulation of Rac protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARF6 ADP ribosylation factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:30,482,191...30,486,741
Ensembl chr14:48,789,329...48,789,856 		JBrowse link
G ARHGAP17 Rho GTPase activating protein 17 involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr16:25,161,229...25,220,151 JBrowse link
G CADM4 cell adhesion molecule 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:40,564,288...40,581,830
Ensembl chr19:49,172,485...49,180,023 		JBrowse link
G CRK CRK proto-oncogene, adaptor protein ISO RGD PMID:12198159 RGD:1298803 NCBI chr17:1,406,335...1,438,587
Ensembl chr17:1,306,509...1,336,569 		JBrowse link
G DNM2 dynamin 2 ISO RGD PMID:14617821 RGD:9685179 NCBI chr19:10,272,172...10,386,032
Ensembl chr19:10,933,672...11,106,478 		JBrowse link
G GABARAP GABA type A receptor-associated protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,270,316...7,272,365
Ensembl chr17:7,257,659...7,260,276 		JBrowse link
G KBTBD6 kelch repeat and BTB domain containing 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:22,329,845...22,335,301
Ensembl chr13:40,921,761...40,923,813 		JBrowse link
G LOC100968722 chronophin involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:18,552,737...18,585,014
Ensembl chr22:36,391,200...36,407,938 		JBrowse link
G LOC100982140 kelch repeat and BTB domain-containing protein 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:22,397,204...22,401,999
Ensembl chr13:40,989,363...40,991,417 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:60,798,219...60,840,948
Ensembl chr  X:70,852,687...70,894,921 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:40,588,100...40,616,479
Ensembl chr19:49,197,341...49,222,561
Ensembl chr19:49,197,341...49,222,561 		JBrowse link
G RASGRF1 Ras protein specific guanine nucleotide releasing factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:57,933,152...58,063,824
Ensembl chr15:76,891,556...77,022,534 		JBrowse link
G SSX2IP SSX family member 2 interacting protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22027834) Ensembl
MGI		 PMID:22027834 GO_REF:0000107 NCBI chr 1:117,192,699...117,239,423
Ensembl chr 1:86,052,733...86,105,769 		JBrowse link
regulation of Ral protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RALGPS1 Ral GEF with PH domain and SH3 binding motif 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:98,033,100...98,342,582
Ensembl chr 9:126,689,557...126,992,628 		JBrowse link
G RGL2 ral guanine nucleotide dissociation stimulator like 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24069211) Ensembl
MGI		 PMID:24069211 GO_REF:0000107 NCBI chr 6:32,863,954...32,871,684
Ensembl chr 6:33,978,024...33,985,749 		JBrowse link
regulation of Rap protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBL Cbl proto-oncogene involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12671687) Ensembl
MGI		 PMID:12671687 GO_REF:0000107 NCBI chr11:114,044,996...114,149,204
Ensembl chr11:117,973,187...118,074,671 		JBrowse link
G KIF14 kinesin family member 14 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23209302) MGI
Ensembl		 PMID:23209302 GO_REF:0000107 NCBI chr 1:176,156,870...176,223,093
Ensembl chr 1:180,462,578...180,526,323 		JBrowse link
G RDX radixin involved_in ISO PMID:21047789 UniProt PMID:21047789 RGD:10054076 NCBI chr11:105,075,716...105,176,660
Ensembl chr11:108,921,477...109,005,557 		JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 ISO RGD PMID:15901773 RGD:1598578 NCBI chr17:72,928,692...73,001,892
Ensembl chr17:78,476,807...78,495,649 		JBrowse link
regulation of Ras protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLCN folliculin involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:34,057,127...34,081,637
Ensembl chr17:38,988,518...39,013,160 		JBrowse link
G FOXM1 forkhead box M1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:2,978,400...2,999,077
Ensembl chr12:2,910,028...2,930,503 		JBrowse link
G ICMT isoprenylcysteine carboxyl methyltransferase acts_upstream_of_or_within ISO (PMID:14966563) MGI PMID:14966563 NCBI chr 1:4,987,384...5,002,213
Ensembl chr 1:6,246,570...6,258,746 		JBrowse link
G LOC100987922 SH2B adapter protein 2 ISO RGD PMID:9856458 RGD:68805
G RABL3 RAB, member of RAS oncogene family like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:117,794,224...117,850,184
Ensembl chr 3:124,707,984...124,748,983 		JBrowse link
G RASGRF1 Ras protein specific guanine nucleotide releasing factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:57,933,152...58,063,824
Ensembl chr15:76,891,556...77,022,534 		JBrowse link
G SYDE1 synapse defective Rho GTPase homolog 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27917469) TreeGrafter
MGI		 PMID:27917469 GO_REF:0000118 NCBI chr19:14,640,493...14,648,080
Ensembl chr19:15,625,096...15,631,600 		JBrowse link
G SYDE2 synapse defective Rho GTPase homolog 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:117,713,925...117,759,382
Ensembl chr 1:86,571,431...86,615,051 		JBrowse link
regulation of Rho protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKAP13 A-kinase anchoring protein 13 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:64,076,422...64,438,109
Ensembl chr15:83,387,667...83,651,362 		JBrowse link
G ARHGAP20 Rho GTPase activating protein 20 involved_in IEA InterPro GO_REF:0000002 NCBI chr11:105,457,931...105,593,644
Ensembl chr11:109,289,419...109,437,294 		JBrowse link
G ARHGDIA Rho GDP dissociation inhibitor alpha involved_in ISO (PMID:8262133) UniProt PMID:8262133 NCBI chr17:76,273,196...76,276,942
Ensembl chr17:81,975,340...81,978,447 		JBrowse link
G ARHGDIB Rho GDP dissociation inhibitor beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:14,944,746...14,964,357
Ensembl chr12:15,341,491...15,361,160 		JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15996550) TreeGrafter
MGI		 PMID:15996550 GO_REF:0000118 NCBI chr 1:131,282,514...131,326,535
Ensembl chr 1:135,112,040...135,159,299 		JBrowse link
G ARHGEF28 Rho guanine nucleotide exchange factor 28 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:41,376,631...41,690,868
Ensembl chr 5:41,976,692...42,231,634 		JBrowse link
G BCR BCR activator of RhoGEF and GTPase involved_in ISO (PMID:23940119) UniProt PMID:23940119
G CDC42SE1 CDC42 small effector 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:126,400,094...126,408,769
Ensembl chr 1:130,047,765...130,056,447 		JBrowse link
G CDC42SE2 CDC42 small effector 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:126,689,882...126,827,208
Ensembl chr 5:132,954,110...132,989,170 		JBrowse link
G CDH2 cadherin 2 ISO RGD PMID:16515795 RGD:1582675 NCBI chr18:21,210,001...21,435,919
Ensembl chr18:24,812,019...25,008,325 		JBrowse link
G DLC1 DLC1 Rho GTPase activating protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:12,282,190...12,809,770
Ensembl chr 8:9,037,742...9,460,233 		JBrowse link
G EPS8 EGFR pathway substrate 8, signaling adaptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:15,617,536...15,788,537
Ensembl chr12:16,013,276...16,076,117 		JBrowse link
G EPS8L1 EPS8 signaling adaptor L1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:52,114,011...52,125,981
Ensembl chr19:60,803,996...60,819,833 		JBrowse link
G EPS8L2 EPS8 signaling adaptor L2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:720,528...741,623
Ensembl chr11:765,689...787,128 		JBrowse link
G FLOT1 flotillin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19458231) Ensembl
MGI		 PMID:19458231 GO_REF:0000107 NCBI chr 6:30,472,839...30,487,809
Ensembl chr 6:31,342,033...31,357,559 		JBrowse link
G KANK1 KN motif and ankyrin repeat domains 1 involved_in ISO (PMID:25961457) UniProt PMID:25961457 NCBI chr 9:550,713...556,230 JBrowse link
G KANK2 KN motif and ankyrin repeat domains 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:10,713,582...10,746,371
Ensembl chr19:11,426,149...11,457,359 		JBrowse link
G MYO9B myosin IXB involved_in ISO (PMID:26529257) UniProt PMID:26529257 NCBI chr19:16,563,005...16,700,312 JBrowse link
G MYO9B myosin IXB involved_in IEA Ensembl GO_REF:0000107 Ensembl chr19:17,562,568...17,674,279 JBrowse link
G NCK2 NCK adaptor protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2A:95,939,197...96,089,163
Ensembl chr2A:106,898,547...106,976,363 		JBrowse link
G OPHN1 oligophrenin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:57,288,297...57,674,685
Ensembl chr  X:67,359,364...67,739,114 		JBrowse link
G PDCD10 programmed cell death 10 NOT|involved_in ISO (PMID:20332113) UniProt PMID:20332113 NCBI chr 3:164,703,909...164,755,085
Ensembl chr 3:172,760,923...172,811,430 		JBrowse link
G STARD13 StAR related lipid transfer domain containing 13 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:14,359,252...14,607,742
Ensembl chr13:32,789,587...33,038,606 		JBrowse link
G STARD8 StAR related lipid transfer domain containing 8 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:57,890,362...57,968,391
Ensembl chr  X:67,954,883...68,031,958 		JBrowse link
G TAGAP T cell activation RhoGTPase activating protein involved_in IEA InterPro GO_REF:0000002 NCBI chr 6:156,923,859...156,934,714
Ensembl chr 6:161,938,457...161,949,158 		JBrowse link
regulation of small GTPase mediated signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMOT angiomotin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17699752) Ensembl
MGI		 PMID:17699752 GO_REF:0000107 NCBI chr  X:101,907,032...101,973,052
Ensembl chr  X:112,362,633...112,428,216 		JBrowse link
G ARHGAP18 Rho GTPase activating protein 18 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:127,368,377...127,558,136
Ensembl chr 6:131,477,383...131,609,221 		JBrowse link
G ARHGAP19 Rho GTPase activating protein 19 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:93,845,870...93,917,842
Ensembl chr10:97,340,568...97,412,538 		JBrowse link
G ARHGAP28 Rho GTPase activating protein 28 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr18:7,366,986...7,548,782
Ensembl chr18:9,690,107...9,775,270 		JBrowse link
G ARHGAP29 Rho GTPase activating protein 29 involved_in IEA UniProt GO_REF:0000117 NCBI chr 1:96,835,259...96,910,999
Ensembl chr 1:95,561,933...95,640,214 		JBrowse link
G ARHGAP40 Rho GTPase activating protein 40 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:34,926,329...34,975,079
Ensembl chr20:36,034,643...36,083,390 		JBrowse link
G ARHGAP45 Rho GTPase activating protein 45 involved_in IEA UniProt GO_REF:0000117 NCBI chr19:41,207...61,193 JBrowse link
G ARHGEF11 Rho guanine nucleotide exchange factor 11 involved_in IEA UniProt GO_REF:0000117 NCBI chr 1:132,277,514...132,390,041
Ensembl chr 1:136,101,732...136,208,896 		JBrowse link
G ARHGEF12 Rho guanine nucleotide exchange factor 12 involved_in IEA UniProt GO_REF:0000117 NCBI chr11:115,173,575...115,327,040
Ensembl chr11:119,098,903...119,251,522 		JBrowse link
G CDC42BPA CDC42 binding protein kinase alpha involved_in ISO PMID:9418861 UniProt PMID:9418861 RGD:632451 NCBI chr 1:202,448,571...202,780,486
Ensembl chr 1:207,438,330...207,766,907 		JBrowse link
G CHN1 chimerin 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr2B:62,074,405...62,283,013 JBrowse link
G CHN2 chimerin 2 involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000117 NCBI chr 7:29,840,194...30,157,363
Ensembl chr 7:29,434,591...29,748,525 		JBrowse link
G GARNL3 GTPase activating Rap/RanGAP domain like 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr 9:98,343,954...98,514,381
Ensembl chr 9:127,038,457...127,168,056 		JBrowse link
G GMIP GEM interacting protein involved_in IEA UniProt GO_REF:0000117 NCBI chr19:19,066,700...19,080,904
Ensembl chr19:20,063,086...20,076,786 		JBrowse link
G IQSEC3 IQ motif and Sec7 domain ArfGEF 3 involved_in ISO PMID:21198641 UniProt PMID:21198641 RGD:8554231 NCBI chr12:128,587...236,302
Ensembl chr12:105,804...209,812 		JBrowse link
G MYO9A myosin IXA involved_in IEA UniProt GO_REF:0000117 NCBI chr15:50,771,747...51,069,700
Ensembl chr15:69,541,318...69,760,771 		JBrowse link
G MYO9B myosin IXB involved_in IEA UniProt GO_REF:0000117 Ensembl chr19:17,562,568...17,674,279 JBrowse link
G PREX1 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr20:44,965,850...45,169,891
Ensembl chr20:46,033,937...46,226,500 		JBrowse link
G PREX2 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 involved_in IEA UniProt GO_REF:0000117 NCBI chr 8:64,489,817...64,769,602
Ensembl chr 8:66,215,974...66,430,138 		JBrowse link
G RACGAP1 Rac GTPase activating protein 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr12:38,729,885...38,766,063
Ensembl chr12:39,625,796...39,672,256 		JBrowse link
G RALGAPA1 Ral GTPase activating protein catalytic subunit alpha 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr14:16,292,189...16,562,880
Ensembl chr14:34,472,880...34,743,430 		JBrowse link
G RALGAPA2 Ral GTPase activating protein catalytic subunit alpha 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr20:20,338,629...20,662,926
Ensembl chr20:20,299,638...20,625,443 		JBrowse link
G RALGAPB Ral GTPase activating protein non-catalytic subunit beta involved_in IEA InterPro GO_REF:0000002 NCBI chr20:34,797,472...34,903,367
Ensembl chr20:35,906,029...36,011,685 		JBrowse link
G RAP1GAP RAP1 GTPase activating protein involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:20,790,076...20,860,511
Ensembl chr 1:21,754,733...21,824,405 		JBrowse link
G RAP1GAP2 RAP1 GTPase activating protein 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr17:2,742,454...3,031,659
Ensembl chr17:2,760,790...3,025,393 		JBrowse link
G SIPA1 signal-induced proliferation-associated 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr11:60,997,292...61,010,155
Ensembl chr11:64,335,136...64,344,955 		JBrowse link
G SIPA1L1 signal induced proliferation associated 1 like 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr14:51,909,444...52,328,719
Ensembl chr14:71,038,600...71,192,916 		JBrowse link
G SIPA1L2 signal induced proliferation associated 1 like 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:207,944,776...208,180,227
Ensembl chr 1:212,966,023...213,101,179 		JBrowse link
G SIPA1L3 signal induced proliferation associated 1 like 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr19:35,006,279...35,317,501
Ensembl chr19:43,749,134...43,869,953 		JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr21:17,483,273...17,925,301
Ensembl chr21:30,868,308...31,016,883 		JBrowse link
G TIAM2 TIAM Rac1 associated GEF 2 involved_in IEA UniProt GO_REF:0000117 NCBI chr 6:152,809,716...153,074,427
Ensembl chr 6:158,902,783...159,038,777 		JBrowse link
G TSC2 TSC complex subunit 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr16:615,776...655,411
Ensembl chr16:2,135,696...2,175,569 		JBrowse link
Rho protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of ISO (PMID:23595732) MGI PMID:23595732 NCBI chr 1:154,586,423...154,711,621
Ensembl chr 1:158,280,994...158,313,915 		JBrowse link
G ADGRG1 adhesion G protein-coupled receptor G1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:37,896,177...37,942,040
Ensembl chr16:57,036,425...57,074,221 		JBrowse link
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:18306009 RGD:5129131 NCBI chr10:110,642,491...110,646,595 JBrowse link
G AGTR1 angiotensin II receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:145,722,475...145,767,550
Ensembl chr 3:153,341,947...153,345,380 		JBrowse link
G ARHGAP27 Rho GTPase activating protein 27 involved_in ISO PMID:15147912 HGNC-UCL PMID:15147912 RGD:1302833 NCBI chr17:11,894,453...11,933,618
Ensembl chr17:12,069,342...12,105,357 		JBrowse link
G ARHGAP35 Rho GTPase activating protein 35 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:23595732) Ensembl
MGI
TreeGrafter		 PMID:23595732 GO_REF:0000107 GO_REF:0000118 NCBI chr19:43,850,692...43,994,487
Ensembl chr19:52,435,379...52,521,104 		JBrowse link
G ARHGAP5 Rho GTPase activating protein 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:12,844,042...12,934,411
Ensembl chr14:31,036,511...31,125,349 		JBrowse link
G ARHGDIA Rho GDP dissociation inhibitor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15093731) Ensembl
MGI
TreeGrafter
InterPro		 PMID:15093731 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr17:76,273,196...76,276,942
Ensembl chr17:81,975,340...81,978,447 		JBrowse link
G ARHGDIB Rho GDP dissociation inhibitor beta involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr12:14,944,746...14,964,357
Ensembl chr12:15,341,491...15,361,160 		JBrowse link
G ARHGDIG Rho GDP dissociation inhibitor gamma involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 Ensembl chr16:271,739...273,605 JBrowse link
G ARHGEF11 Rho guanine nucleotide exchange factor 11 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:132,277,514...132,390,041
Ensembl chr 1:136,101,732...136,208,896 		JBrowse link
G ARHGEF12 Rho guanine nucleotide exchange factor 12 involved_in IEA InterPro GO_REF:0000002 NCBI chr11:115,173,575...115,327,040
Ensembl chr11:119,098,903...119,251,522 		JBrowse link
G ARHGEF7 Rho guanine nucleotide exchange factor 7 involved_in ISO (PMID:25500533) ParkinsonsUK-UCL PMID:25500533 NCBI chr13:92,246,107...92,436,173
Ensembl chr13:111,427,905...111,545,413 		JBrowse link
G BCL6 BCL6 transcription repressor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15860730) Ensembl
MGI		 PMID:15860730 GO_REF:0000107 NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124 		JBrowse link
G CDC42EP1 CDC42 effector protein 1 acts_upstream_of_or_within ISO (PMID:10490598) MGI PMID:10490598 NCBI chr22:18,478,478...18,487,416
Ensembl chr22:36,316,902...36,319,349 		JBrowse link
G CDC42EP4 CDC42 effector protein 4 acts_upstream_of_or_within ISO (PMID:10490598) MGI PMID:10490598 NCBI chr17:67,212,571...67,239,844 JBrowse link
G CDC42EP5 CDC42 effector protein 5 acts_upstream_of_or_within ISO (PMID:10490598) MGI PMID:10490598 NCBI chr19:51,411,848...51,419,686 JBrowse link
G CDH13 cadherin 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:63,255,482...64,418,053
Ensembl chr16:82,883,184...83,808,996 		JBrowse link
G CELSR1 cadherin EGF LAG seven-pass G-type receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20223754) Ensembl
MGI		 PMID:20223754 GO_REF:0000107 Ensembl chr22:45,428,159...45,604,453 JBrowse link
G COL1A2 collagen type I alpha 2 chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:86,344,657...86,381,282
Ensembl chr 7:99,935,185...99,971,803 		JBrowse link
G CTNNAL1 catenin alpha like 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12270917) MGI
TreeGrafter
InterPro		 PMID:12270917 GO_REF:0000002 GO_REF:0000118 NCBI chr 9:80,093,492...80,164,461 JBrowse link
G EDNRA endothelin receptor type A ISO RGD PMID:16543720 RGD:4892323 NCBI chr 4:139,815,336...139,879,600
Ensembl chr 4:151,476,356...151,536,497 		JBrowse link
G EPS8 EGFR pathway substrate 8, signaling adaptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:15,617,536...15,788,537
Ensembl chr12:16,013,276...16,076,117 		JBrowse link
G EPS8L1 EPS8 signaling adaptor L1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:52,114,011...52,125,981
Ensembl chr19:60,803,996...60,819,833 		JBrowse link
G EPS8L2 EPS8 signaling adaptor L2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:720,528...741,623
Ensembl chr11:765,689...787,128 		JBrowse link
G GNA12 G protein subunit alpha 12 acts_upstream_of_or_within ISO (PMID:10037795) MGI PMID:10037795 NCBI chr 7:2,989,832...3,104,848 JBrowse link
G GNA13 G protein subunit alpha 13 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10037795) InterPro
MGI
TreeGrafter
Ensembl		 PMID:10037795 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr17:58,957,682...59,005,182 JBrowse link
G HACD3 3-hydroxyacyl-CoA dehydratase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10747961) Ensembl
MGI		 PMID:10747961 GO_REF:0000107 NCBI chr15:44,473,542...44,520,885
Ensembl chr15:62,752,762...62,799,950 		JBrowse link
G ITGA3 integrin subunit alpha 3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:23595732) Ensembl
MGI		 PMID:23595732 GO_REF:0000107 NCBI chr17:44,145,974...44,181,343
Ensembl chr17:49,019,892...49,055,245 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462 		JBrowse link
G MCF2L MCF.2 cell line derived transforming sequence like acts_upstream_of_or_within ISO (PMID:12637522) MGI PMID:12637522 NCBI chr13:94,024,030...94,239,491
Ensembl chr13:113,111,066...113,309,224 		JBrowse link
G MYO9B myosin IXB acts_upstream_of_or_within ISO (PMID:20566876) RGD
MGI		 PMID:7882973 PMID:20566876 RGD:633447 NCBI chr19:16,563,005...16,700,312 JBrowse link
G MYO9B myosin IXB involved_in IEA InterPro GO_REF:0000002 Ensembl chr19:17,562,568...17,674,279 JBrowse link
G NCK2 NCK adaptor protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2A:95,939,197...96,089,163
Ensembl chr2A:106,898,547...106,976,363 		JBrowse link
G NFIX nuclear factor I X acts_upstream_of_or_within ISO (PMID:32183151) MGI PMID:32183151 NCBI chr19:12,557,020...12,660,316
Ensembl chr19:13,327,690...13,402,406 		JBrowse link
G NGFR nerve growth factor receptor involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:8,089,600...8,109,361
Ensembl chr17:8,075,316...8,094,966 		JBrowse link
G PDPN podoplanin involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:12,728,569...12,759,781
Ensembl chr 1:13,728,233...13,759,584 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 acts_upstream_of_or_within ISO (PMID:12890700) MGI PMID:12890700 NCBI chr17:58,417,134...58,526,409
Ensembl chr17:63,511,784...63,579,067 		JBrowse link
G PHACTR4 phosphatase and actin regulator 4 involved_in IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107 NCBI chr 1:27,634,440...27,768,139
Ensembl chr 1:28,741,081...28,794,870 		JBrowse link
G PLEKHG5 pleckstrin homology and RhoGEF domain containing G5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:5,228,681...5,259,554
Ensembl chr 1:6,481,782...6,535,643 		JBrowse link
G PTH parathyroid hormone ISO RGD PMID:15476589 RGD:1601516 NCBI chr11:13,653,777...13,657,901
Ensembl chr11:13,347,838...13,351,802 		JBrowse link
G RACGAP1 Rac GTPase activating protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:38,729,885...38,766,063
Ensembl chr12:39,625,796...39,672,256 		JBrowse link
G RHOA ras homolog family member A acts_upstream_of_or_within
involved_in		 ISO
IEA		 PMID:29453251 MGI
TreeGrafter
Ensembl		 PMID:29453251 GO_REF:0000107 GO_REF:0000118 RGD:42721986 NCBI chr 3:49,282,009...49,339,887 JBrowse link
G RHOG ras homolog family member G acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12376551) MGI
Ensembl		 PMID:12376551 GO_REF:0000107 NCBI chr11:3,698,179...3,712,402
Ensembl chr11:3,811,877...3,812,452 		JBrowse link
G RHOJ ras homolog family member J involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10967094) Ensembl
MGI		 PMID:10967094 GO_REF:0000107 NCBI chr14:43,783,185...43,872,000
Ensembl chr14:62,039,418...62,126,908 		JBrowse link
G RIPOR1 RHO family interacting cell polarization regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:47,872,769...47,890,776
Ensembl chr16:67,268,180...67,278,445 		JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 PMID:18332105 MGI
TreeGrafter
Ensembl
UniProt
InterPro		 PMID:18332105 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 RGD:8554725 NCBI chr18:14,192,293...14,352,357
Ensembl chr18:17,833,047...17,990,086 		JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 PMID:18332105 MGI
TreeGrafter
InterPro
UniProt		 PMID:18332105 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 RGD:8554725 NCBI chr2A:11,167,353...11,331,339
Ensembl chr2A:11,318,370...11,478,986 		JBrowse link
G RTKN rhotekin involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:74,492,520...74,509,037
Ensembl chr2A:75,998,494...76,015,046 		JBrowse link
G SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 acts_upstream_of_or_within ISO (PMID:11672528) MGI PMID:11672528 NCBI chr12:24,760,093...25,066,794
Ensembl chr12:25,262,893...25,564,180 		JBrowse link
G SYNJ2BP synaptojanin 2 binding protein acts_upstream_of_or_within ISO (PMID:11882656) MGI PMID:11882656 NCBI chr14:50,958,861...51,009,395
Ensembl chr14:69,835,548...69,879,537 		JBrowse link
G TAX1BP3 Tax1 binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:3,713,211...3,718,959
Ensembl chr17:3,709,600...3,715,342 		JBrowse link
G VANGL2 VANGL planar cell polarity protein 2 acts_upstream_of_or_within ISO (PMID:20223754) MGI PMID:20223754 NCBI chr 1:135,754,897...135,783,031
Ensembl chr 1:139,683,745...139,704,281 		JBrowse link
G WAS WASP actin nucleation promoting factor NOT|involved_in ISO (PMID:8625410) CAFA PMID:8625410 NCBI chr  X:40,982,132...40,989,767
Ensembl chr  X:48,842,765...48,850,380 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16447
    cellular process 15499
      signal transduction 5443
        intracellular signal transduction 2614
          intracellular signaling cassette 1830
            small GTPase-mediated signal transduction 445
              ARF protein signal transduction + 24
              Rab protein signal transduction + 19
              Rac protein signal transduction + 54
              Ral protein signal transduction + 6
              Ran protein signal transduction 0
              Rap protein signal transduction + 14
              Ras protein signal transduction + 120
              Rho protein signal transduction + 136
              negative regulation of small GTPase mediated signal transduction + 63
              positive regulation of small GTPase mediated signal transduction + 89
              regulation of small GTPase mediated signal transduction + 257
              septation initiation signaling + 0
Path 2
Term Annotations click to browse term
  biological_process 16447
    biological regulation 11463
      regulation of biological process 11110
        signaling 5940
          signal transduction 5443
            intracellular signal transduction 2614
              intracellular signaling cassette 1830
                small GTPase-mediated signal transduction 445
                  ARF protein signal transduction + 24
                  Rab protein signal transduction + 19
                  Rac protein signal transduction + 54
                  Ral protein signal transduction + 6
                  Ran protein signal transduction 0
                  Rap protein signal transduction + 14
                  Ras protein signal transduction + 120
                  Rho protein signal transduction + 136
                  negative regulation of small GTPase mediated signal transduction + 63
                  positive regulation of small GTPase mediated signal transduction + 89
                  regulation of small GTPase mediated signal transduction + 257
                  septation initiation signaling + 0
paths to the root