FLOT1 (flotillin 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: FLOT1 (flotillin 1) Pan paniscus
Analyze
Symbol: FLOT1
Name: flotillin 1
RGD ID: 11936924
Description: ENCODES a protein that exhibits ionotropic glutamate receptor binding (ortholog); INVOLVED IN axonogenesis (ortholog); plasma membrane raft organization (ortholog); positive regulation of protein phosphorylation (ortholog); ASSOCIATED WITH megacolon (ortholog); proteasome-associated autoinflammatory syndrome 1 (ortholog); Q fever (ortholog); FOUND IN apical part of cell (ortholog); apical plasma membrane (ortholog); caveola (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: flotillin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2545,288,663 - 45,303,454 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1641,251,507 - 41,266,371 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0630,472,839 - 30,487,809 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1631,342,026 - 31,357,505 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl631,342,033 - 31,357,559 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
FLOT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2545,288,663 - 45,303,454 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1641,251,507 - 41,266,371 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0630,472,839 - 30,487,809 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1631,342,026 - 31,357,505 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl631,342,033 - 31,357,559 (-)Ensemblpanpan1.1panPan2
FLOT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38630,727,709 - 30,742,687 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl630,727,709 - 30,742,732 (-)EnsemblGRCh38hg38GRCh38
GRCh37630,695,486 - 30,710,464 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36630,803,490 - 30,818,432 (-)NCBINCBI36Build 36hg18NCBI36
Build 34630,803,491 - 30,818,432NCBI
Celera632,293,643 - 32,308,593 (-)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef630,495,459 - 30,510,242 (-)NCBIHuRef
CHM1_1630,697,639 - 30,712,561 (-)NCBICHM1_1
T2T-CHM13v2.0630,591,911 - 30,606,890 (-)NCBIT2T-CHM13v2.0
Flot1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391736,134,243 - 36,143,674 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1736,134,122 - 36,143,683 (+)EnsemblGRCm39 Ensembl
GRCm381735,823,320 - 35,832,789 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1735,823,230 - 35,832,791 (+)EnsemblGRCm38mm10GRCm38
MGSCv371735,960,302 - 35,969,732 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361735,431,410 - 35,440,840 (+)NCBIMGSCv36mm8
Celera1739,333,424 - 39,342,847 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.7NCBI
Flot1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8202,922,662 - 2,932,906 (-)NCBIGRCr8
mRatBN7.2202,917,864 - 2,927,993 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl202,917,137 - 2,927,978 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx202,969,295 - 2,979,369 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0202,974,276 - 2,984,354 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0203,000,638 - 3,010,732 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0203,427,890 - 3,438,418 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,427,880 - 3,438,396 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0205,524,708 - 5,535,232 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,065,792 - 3,076,166 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1203,066,008 - 3,169,167 (-)NCBI
Celera20343,778 - 353,887 (-)NCBICelera
Cytogenetic Map20p12NCBI
Flot1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955583713,560 - 729,924 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955583717,246 - 729,924 (-)NCBIChiLan1.0ChiLan1.0
FLOT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.112517,941 - 528,677 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl12516,032 - 528,637 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha12655,207 - 665,931 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.012661,078 - 671,802 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl12656,880 - 671,882 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.112519,006 - 529,724 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.012587,853 - 598,598 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.012656,440 - 667,178 (-)NCBIUU_Cfam_GSD_1.0
Flot1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494634,021,923 - 34,035,815 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936837380,288 - 401,071 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936837387,012 - 401,076 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FLOT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl723,253,162 - 23,265,106 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1723,253,157 - 23,265,165 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2726,975,124 - 26,987,109 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FLOT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11741,714,354 - 41,725,820 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1741,714,402 - 41,725,397 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604430,425,408 - 30,437,271 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Flot1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475424,992,929 - 25,003,759 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475424,992,961 - 25,000,463 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000039278   ⟹   ENSPPAP00000016581
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl631,342,033 - 31,357,559 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000039305   ⟹   ENSPPAP00000016608
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl631,342,413 - 31,356,844 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000039306   ⟹   ENSPPAP00000016609
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl631,342,413 - 31,356,844 (-)Ensembl
RefSeq Acc Id: XM_003807347   ⟹   XP_003807395
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2545,288,663 - 45,303,454 (-)NCBI
NHGRI_mPanPan1641,251,507 - 41,266,371 (-)NCBI
Mhudiblu_PPA_v0630,472,849 - 30,487,648 (-)NCBI
PanPan1.1631,342,121 - 31,357,505 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024929086   ⟹   XP_024784854
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2545,288,663 - 45,303,454 (-)NCBI
NHGRI_mPanPan1641,251,507 - 41,266,356 (-)NCBI
Mhudiblu_PPA_v0630,472,839 - 30,487,809 (-)NCBI
PanPan1.1631,342,121 - 31,357,505 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003807395 (Get FASTA)   NCBI Sequence Viewer  
  XP_024784854 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000016581
  ENSPPAP00000016581.1
  ENSPPAP00000016608
  ENSPPAP00000016608.1
  ENSPPAP00000016609.1
RefSeq Acc Id: XP_003807395   ⟸   XM_003807347
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AGW3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024784854   ⟸   XM_024929086
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AHV4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000016609   ⟸   ENSPPAT00000039306
Ensembl Acc Id: ENSPPAP00000016608   ⟸   ENSPPAT00000039305
Ensembl Acc Id: ENSPPAP00000016581   ⟸   ENSPPAT00000039278
Protein Domains
Band


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031390 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000039278.1 UniProtKB/TrEMBL
  ENSPPAT00000039305.1 UniProtKB/TrEMBL
  ENSPPAT00000039306.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.479.30 UniProtKB/TrEMBL
InterPro Band_7 UniProtKB/TrEMBL
  Band_7/SPFH_dom_sf UniProtKB/TrEMBL
  Flotillin_C UniProtKB/TrEMBL
  Flotillin_fam UniProtKB/TrEMBL
KEGG Report pps:100970836 UniProtKB/TrEMBL
NCBI Gene FLOT1 ENTREZGENE
PANTHER FLOTILLIN-1 UniProtKB/TrEMBL
  PTHR13806 UniProtKB/TrEMBL
Pfam Band_7 UniProtKB/TrEMBL
  Flot UniProtKB/TrEMBL
SMART PHB UniProtKB/TrEMBL
Superfamily-SCOP SSF117892 UniProtKB/TrEMBL
UniProt A0A2R9AGW3 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AHV4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9ANS6_PANPA UniProtKB/TrEMBL