NISCH (nischarin) - Rat Genome Database

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Gene: NISCH (nischarin) Pan paniscus
Analyze
Symbol: NISCH
Name: nischarin
RGD ID: 11773329
Description: ENCODES a protein that exhibits identical protein binding (inferred); integrin binding (inferred); phosphatidylinositol binding (inferred); INVOLVED IN actin cytoskeleton organization (ortholog); glucose metabolic process (ortholog); negative regulation of cell migration (ortholog); ASSOCIATED WITH Bradycardia (ortholog); Breast Neoplasms (ortholog); congenital disorder of glycosylation In (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); intercellular bridge (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2252,450,617 - 52,488,273 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1352,455,389 - 52,493,045 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0352,397,576 - 52,435,127 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1353,626,176 - 53,663,128 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl353,626,317 - 53,662,567 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NISCH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2252,450,617 - 52,488,273 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1352,455,389 - 52,493,045 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0352,397,576 - 52,435,127 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1353,626,176 - 53,663,128 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl353,626,317 - 53,662,567 (+)Ensemblpanpan1.1panPan2
NISCH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38352,455,604 - 52,493,068 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl352,455,118 - 52,493,068 (+)EnsemblGRCh38hg38GRCh38
GRCh37352,489,620 - 52,527,084 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36352,464,564 - 52,502,128 (+)NCBINCBI36Build 36hg18NCBI36
Build 34352,464,671 - 52,502,125NCBI
Celera352,468,769 - 52,506,327 (+)NCBICelera
Cytogenetic Map3p21.1NCBI
HuRef352,552,184 - 52,589,631 (+)NCBIHuRef
CHM1_1352,441,901 - 52,479,443 (+)NCBICHM1_1
T2T-CHM13v2.0352,488,505 - 52,525,966 (+)NCBIT2T-CHM13v2.0
Nisch
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391430,892,885 - 30,928,783 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1430,892,887 - 30,938,903 (-)EnsemblGRCm39 Ensembl
GRCm381431,170,928 - 31,206,826 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1431,170,930 - 31,216,946 (-)EnsemblGRCm38mm10GRCm38
MGSCv371431,984,114 - 32,020,012 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361429,999,937 - 30,020,559 (-)NCBIMGSCv36mm8
Celera1427,429,490 - 27,465,449 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1419.09NCBI
Nisch
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8166,370,809 - 6,407,104 (-)NCBIGRCr8
mRatBN7.2166,364,370 - 6,400,675 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl166,364,374 - 6,400,668 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx166,388,854 - 6,412,881 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0167,534,079 - 7,558,106 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0166,395,765 - 6,419,885 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0167,254,372 - 7,290,670 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl167,254,974 - 7,290,561 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0167,182,941 - 7,219,320 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4166,601,521 - 6,637,734 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1166,602,120 - 6,637,709 (-)NCBI
Celera168,788,272 - 8,824,554 (+)NCBICelera
Cytogenetic Map16p16NCBI
Nisch
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554302,443,029 - 2,491,123 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554302,443,029 - 2,488,267 (+)NCBIChiLan1.0ChiLan1.0
NISCH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12037,278,660 - 37,312,549 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2037,279,282 - 37,312,636 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2037,260,489 - 37,294,003 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02037,628,115 - 37,662,575 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2037,628,116 - 37,662,560 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12036,992,617 - 37,026,536 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02037,401,248 - 37,435,163 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02037,679,538 - 37,719,774 (-)NCBIUU_Cfam_GSD_1.0
Nisch
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118170,156,942 - 170,192,753 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364733,295,515 - 3,331,324 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NISCH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1334,595,782 - 34,630,303 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11334,595,788 - 34,630,306 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21337,809,589 - 37,844,045 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NISCH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12213,821,026 - 13,860,430 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2213,841,352 - 13,860,498 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041153,039,458 - 153,078,870 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nisch
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248224,726,407 - 4,763,508 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248224,725,715 - 4,763,579 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000016103   ⟹   ENSPPAP00000003494
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl353,626,317 - 53,662,567 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000016109   ⟹   ENSPPAP00000003496
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl353,626,317 - 53,651,009 (+)Ensembl
RefSeq Acc Id: XM_034956607   ⟹   XP_034812498
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2252,450,622 - 52,488,273 (+)NCBI
NHGRI_mPanPan1352,455,394 - 52,493,045 (+)NCBI
Mhudiblu_PPA_v0352,397,583 - 52,435,127 (+)NCBI
RefSeq Acc Id: XM_034956608   ⟹   XP_034812499
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2252,450,617 - 52,488,273 (+)NCBI
NHGRI_mPanPan1352,455,389 - 52,493,045 (+)NCBI
Mhudiblu_PPA_v0352,397,584 - 52,435,127 (+)NCBI
RefSeq Acc Id: XM_034956609   ⟹   XP_034812500
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2252,450,617 - 52,477,166 (+)NCBI
NHGRI_mPanPan1352,455,389 - 52,481,938 (+)NCBI
Mhudiblu_PPA_v0352,397,576 - 52,424,805 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034812498 (Get FASTA)   NCBI Sequence Viewer  
  XP_034812499 (Get FASTA)   NCBI Sequence Viewer  
  XP_034812500 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000003494.1
  ENSPPAP00000003496.1
RefSeq Acc Id: XP_034812500   ⟸   XM_034956609
- Peptide Label: isoform X3
- UniProtKB: A0A2R8ZL75 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034812498   ⟸   XM_034956607
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZF67 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034812499   ⟸   XM_034956608
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZF67 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000003494   ⟸   ENSPPAT00000016103
Ensembl Acc Id: ENSPPAP00000003496   ⟸   ENSPPAT00000016109
Protein Domains
PX


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000014444 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000016103.1 UniProtKB/TrEMBL
  ENSPPAT00000016109.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1520.10 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_4 UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  Nischarin_PX UniProtKB/TrEMBL
  PX_dom UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/TrEMBL
NCBI Gene NISCH ENTREZGENE
PANTHER NISCHARIN UniProtKB/TrEMBL
  NISCHARIN RELATED UniProtKB/TrEMBL
Pfam LRR_1 UniProtKB/TrEMBL
  LRR_4 UniProtKB/TrEMBL
  PF00787 UniProtKB/TrEMBL
PRINTS LEURICHRPT UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
  PS50195 UniProtKB/TrEMBL
SMART LRR_SD22 UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  SM00312 UniProtKB/TrEMBL
Superfamily-SCOP Outer arm dynein light chain 1 UniProtKB/TrEMBL
  SSF64268 UniProtKB/TrEMBL
UniProt A0A2R8ZF67 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZL75 ENTREZGENE, UniProtKB/TrEMBL