Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:Rho protein signal transduction
go back to main search page
Accession:GO:0007266 term browser browse the term
Definition:An intracellular signaling cassette in which a small monomeric GTPase of the Rho subfamily relays a signal.
Synonyms:exact_synonym: Rho mediated signal transduction


show annotations for term's descendants           Sort by:
Rho protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of ISO (PMID:23595732) MGI PMID:23595732 NCBI chr 1:154,586,423...154,711,621
Ensembl chr 1:158,280,994...158,313,915 		JBrowse link
G ADGRG1 adhesion G protein-coupled receptor G1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:37,896,177...37,942,040
Ensembl chr16:57,036,425...57,074,221 		JBrowse link
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:18306009 RGD:5129131 NCBI chr10:110,642,491...110,646,595 JBrowse link
G AGTR1 angiotensin II receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:145,722,475...145,767,550
Ensembl chr 3:153,341,947...153,345,380 		JBrowse link
G ARHGAP35 Rho GTPase activating protein 35 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:23595732) Ensembl
MGI
TreeGrafter		 PMID:23595732 GO_REF:0000107 GO_REF:0000118 NCBI chr19:43,850,692...43,994,487
Ensembl chr19:52,435,379...52,521,104 		JBrowse link
G ARHGAP5 Rho GTPase activating protein 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:12,844,042...12,934,411
Ensembl chr14:31,036,511...31,125,349 		JBrowse link
G ARHGDIA Rho GDP dissociation inhibitor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15093731) Ensembl
MGI
TreeGrafter
InterPro		 PMID:15093731 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr17:76,273,196...76,276,942
Ensembl chr17:81,975,340...81,978,447 		JBrowse link
G ARHGDIB Rho GDP dissociation inhibitor beta involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr12:14,944,746...14,964,357
Ensembl chr12:15,341,491...15,361,160 		JBrowse link
G ARHGDIG Rho GDP dissociation inhibitor gamma involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 Ensembl chr16:271,739...273,605 JBrowse link
G ARHGEF11 Rho guanine nucleotide exchange factor 11 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:132,277,514...132,390,041
Ensembl chr 1:136,101,732...136,208,896 		JBrowse link
G ARHGEF12 Rho guanine nucleotide exchange factor 12 involved_in IEA InterPro GO_REF:0000002 NCBI chr11:115,173,575...115,327,040
Ensembl chr11:119,098,903...119,251,522 		JBrowse link
G ARHGEF7 Rho guanine nucleotide exchange factor 7 involved_in ISO (PMID:25500533) ParkinsonsUK-UCL PMID:25500533 NCBI chr13:92,246,107...92,436,173
Ensembl chr13:111,427,905...111,545,413 		JBrowse link
G BCL6 BCL6 transcription repressor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15860730) Ensembl
MGI		 PMID:15860730 GO_REF:0000107 NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124 		JBrowse link
G CDC42EP1 CDC42 effector protein 1 acts_upstream_of_or_within ISO (PMID:10490598) MGI PMID:10490598 NCBI chr22:18,478,478...18,487,416
Ensembl chr22:36,316,902...36,319,349 		JBrowse link
G CDC42EP4 CDC42 effector protein 4 acts_upstream_of_or_within ISO (PMID:10490598) MGI PMID:10490598 NCBI chr17:67,212,571...67,239,844 JBrowse link
G CDC42EP5 CDC42 effector protein 5 acts_upstream_of_or_within ISO (PMID:10490598) MGI PMID:10490598 NCBI chr19:51,411,848...51,419,686 JBrowse link
G CDH13 cadherin 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:63,255,482...64,418,053
Ensembl chr16:82,883,184...83,808,996 		JBrowse link
G CELSR1 cadherin EGF LAG seven-pass G-type receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20223754) Ensembl
MGI		 PMID:20223754 GO_REF:0000107 Ensembl chr22:45,428,159...45,604,453 JBrowse link
G COL1A2 collagen type I alpha 2 chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:86,344,657...86,381,282
Ensembl chr 7:99,935,185...99,971,803 		JBrowse link
G CTNNAL1 catenin alpha like 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12270917) MGI
TreeGrafter
InterPro		 PMID:12270917 GO_REF:0000002 GO_REF:0000118 NCBI chr 9:80,093,492...80,164,461 JBrowse link
G EDNRA endothelin receptor type A ISO RGD PMID:16543720 RGD:4892323 NCBI chr 4:139,815,336...139,879,600
Ensembl chr 4:151,476,356...151,536,497 		JBrowse link
G EPS8 EGFR pathway substrate 8, signaling adaptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:15,617,536...15,788,537
Ensembl chr12:16,013,276...16,076,117 		JBrowse link
G EPS8L1 EPS8 signaling adaptor L1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:52,114,011...52,125,981
Ensembl chr19:60,803,996...60,819,833 		JBrowse link
G EPS8L2 EPS8 signaling adaptor L2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:720,528...741,623
Ensembl chr11:765,689...787,128 		JBrowse link
G GNA12 G protein subunit alpha 12 acts_upstream_of_or_within ISO (PMID:10037795) MGI PMID:10037795 NCBI chr 7:2,989,832...3,104,848 JBrowse link
G GNA13 G protein subunit alpha 13 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10037795) InterPro
MGI
TreeGrafter
Ensembl		 PMID:10037795 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr17:58,957,682...59,005,182 JBrowse link
G HACD3 3-hydroxyacyl-CoA dehydratase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10747961) Ensembl
MGI		 PMID:10747961 GO_REF:0000107 NCBI chr15:44,473,542...44,520,885
Ensembl chr15:62,752,762...62,799,950 		JBrowse link
G ITGA3 integrin subunit alpha 3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:23595732) Ensembl
MGI		 PMID:23595732 GO_REF:0000107 NCBI chr17:44,145,974...44,181,343
Ensembl chr17:49,019,892...49,055,245 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462 		JBrowse link
G MCF2L MCF.2 cell line derived transforming sequence like acts_upstream_of_or_within ISO (PMID:12637522) MGI PMID:12637522 NCBI chr13:94,024,030...94,239,491
Ensembl chr13:113,111,066...113,309,224 		JBrowse link
G MYO9B myosin IXB acts_upstream_of_or_within ISO (PMID:20566876) RGD
MGI		 PMID:7882973 PMID:20566876 RGD:633447 NCBI chr19:16,563,005...16,700,312 JBrowse link
G MYO9B myosin IXB involved_in IEA InterPro GO_REF:0000002 Ensembl chr19:17,562,568...17,674,279 JBrowse link
G NCK2 NCK adaptor protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2A:95,939,197...96,089,163
Ensembl chr2A:106,898,547...106,976,363 		JBrowse link
G NFIX nuclear factor I X acts_upstream_of_or_within ISO (PMID:32183151) MGI PMID:32183151 NCBI chr19:12,557,020...12,660,316
Ensembl chr19:13,327,690...13,402,406 		JBrowse link
G NGFR nerve growth factor receptor involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:8,089,600...8,109,361
Ensembl chr17:8,075,316...8,094,966 		JBrowse link
G PDPN podoplanin involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:12,728,569...12,759,781
Ensembl chr 1:13,728,233...13,759,584 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 acts_upstream_of_or_within ISO (PMID:12890700) MGI PMID:12890700 NCBI chr17:58,417,134...58,526,409
Ensembl chr17:63,511,784...63,579,067 		JBrowse link
G PHACTR4 phosphatase and actin regulator 4 involved_in IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107 NCBI chr 1:27,634,440...27,768,139
Ensembl chr 1:28,741,081...28,794,870 		JBrowse link
G PLEKHG5 pleckstrin homology and RhoGEF domain containing G5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:5,228,681...5,259,554
Ensembl chr 1:6,481,782...6,535,643 		JBrowse link
G PTH parathyroid hormone ISO RGD PMID:15476589 RGD:1601516 NCBI chr11:13,653,777...13,657,901
Ensembl chr11:13,347,838...13,351,802 		JBrowse link
G RACGAP1 Rac GTPase activating protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:38,729,885...38,766,063
Ensembl chr12:39,625,796...39,672,256 		JBrowse link
G RHOA ras homolog family member A acts_upstream_of_or_within
involved_in		 ISO
IEA		 PMID:29453251 MGI
TreeGrafter
Ensembl		 PMID:29453251 GO_REF:0000107 GO_REF:0000118 RGD:42721986 NCBI chr 3:49,282,009...49,339,887 JBrowse link
G RHOG ras homolog family member G acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12376551) MGI
Ensembl		 PMID:12376551 GO_REF:0000107 NCBI chr11:3,698,179...3,712,402
Ensembl chr11:3,811,877...3,812,452 		JBrowse link
G RHOJ ras homolog family member J involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10967094) Ensembl
MGI		 PMID:10967094 GO_REF:0000107 NCBI chr14:43,783,185...43,872,000
Ensembl chr14:62,039,418...62,126,908 		JBrowse link
G RIPOR1 RHO family interacting cell polarization regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:47,872,769...47,890,776
Ensembl chr16:67,268,180...67,278,445 		JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 PMID:18332105 MGI
TreeGrafter
Ensembl
UniProt
InterPro		 PMID:18332105 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 RGD:8554725 NCBI chr18:14,192,293...14,352,357
Ensembl chr18:17,833,047...17,990,086 		JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 PMID:18332105 MGI
TreeGrafter
InterPro
UniProt		 PMID:18332105 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 RGD:8554725 NCBI chr2A:11,167,353...11,331,339
Ensembl chr2A:11,318,370...11,478,986 		JBrowse link
G RTKN rhotekin involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:74,492,520...74,509,037
Ensembl chr2A:75,998,494...76,015,046 		JBrowse link
G SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 acts_upstream_of_or_within ISO (PMID:11672528) MGI PMID:11672528 NCBI chr12:24,760,093...25,066,794
Ensembl chr12:25,262,893...25,564,180 		JBrowse link
G SYNJ2BP synaptojanin 2 binding protein acts_upstream_of_or_within ISO (PMID:11882656) MGI PMID:11882656 NCBI chr14:50,958,861...51,009,395
Ensembl chr14:69,835,548...69,879,537 		JBrowse link
G TAX1BP3 Tax1 binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:3,713,211...3,718,959
Ensembl chr17:3,709,600...3,715,342 		JBrowse link
G VANGL2 VANGL planar cell polarity protein 2 acts_upstream_of_or_within ISO (PMID:20223754) MGI PMID:20223754 NCBI chr 1:135,754,897...135,783,031
Ensembl chr 1:139,683,745...139,704,281 		JBrowse link
G WAS WASP actin nucleation promoting factor NOT|involved_in ISO (PMID:8625410) CAFA PMID:8625410 NCBI chr  X:40,982,132...40,989,767
Ensembl chr  X:48,842,765...48,850,380 		JBrowse link
Cdc42 protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC42 cell division cycle 42 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:21,245,970...21,286,210 JBrowse link
G LOC100993131 cell division control protein 42 homolog involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:33,260,425...33,262,300 JBrowse link
G NTN1 netrin 1 involved_in ISO PMID:23453953 UniProt PMID:23453953 RGD:10054078 NCBI chr17:42,409,797...42,631,930
Ensembl chr17:47,152,225...47,368,134 		JBrowse link
G RHOJ ras homolog family member J involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:43,783,185...43,872,000
Ensembl chr14:62,039,418...62,126,908 		JBrowse link
G RHOV ras homolog family member V involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:19,814,817...19,816,925
Ensembl chr15:38,064,587...38,066,873 		JBrowse link
G SHTN1 shootin 1 involved_in ISO PMID:23453953 UniProt PMID:23453953 RGD:10054078 NCBI chr10:113,466,218...113,587,490
Ensembl chr10:116,896,155...117,016,223 		JBrowse link
G WAS WASP actin nucleation promoting factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:40,982,132...40,989,767
Ensembl chr  X:48,842,765...48,850,380 		JBrowse link
negative regulation of Rho protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:23595732)
(PMID:22357865)
(PMID:15084284)		 MGI PMID:15084284 PMID:22357865 PMID:23595732 NCBI chr 1:154,586,423...154,711,621
Ensembl chr 1:158,280,994...158,313,915 		JBrowse link
G ADRA1A adrenoceptor alpha 1A acts_upstream_of_or_within ISO PMID:18332105 MGI PMID:18332105 RGD:8554725 NCBI chr 8:25,947,996...26,138,022
Ensembl chr 8:22,853,677...23,044,388 		JBrowse link
G ADRA1B adrenoceptor alpha 1B acts_upstream_of_or_within ISO PMID:18332105 MGI PMID:18332105 RGD:8554725 NCBI chr 5:155,307,148...155,363,785
Ensembl chr 5:161,923,895...161,979,461 		JBrowse link
G ARHGAP35 Rho GTPase activating protein 35 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15084284)
(PMID:23595732)
(PMID:22357865)		 Ensembl
MGI		 PMID:15084284 PMID:22357865 PMID:23595732 GO_REF:0000107 NCBI chr19:43,850,692...43,994,487
Ensembl chr19:52,435,379...52,521,104 		JBrowse link
G ARHGAP42 Rho GTPase activating protein 42 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24335996) Ensembl
MGI		 PMID:24335996 GO_REF:0000107 NCBI chr11:95,655,874...95,962,003
Ensembl chr11:99,159,634...99,460,060 		JBrowse link
G BCL6 BCL6 transcription repressor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15860730) Ensembl
MGI		 PMID:15860730 GO_REF:0000107 NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124 		JBrowse link
G CCDC125 coiled-coil domain containing 125 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:44,667,688...44,717,872
Ensembl chr 5:46,251,209...46,287,598 		JBrowse link
G CUL3 cullin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:111,714,533...111,827,080
Ensembl chr2B:230,289,195...230,378,991 		JBrowse link
G DLC1 DLC1 Rho GTPase activating protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:12,282,190...12,809,770
Ensembl chr 8:9,037,742...9,460,233 		JBrowse link
G FLCN folliculin involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:34,057,127...34,081,637
Ensembl chr17:38,988,518...39,013,160 		JBrowse link
G HEG1 heart development protein with EGF like domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:122,091,832...122,204,436
Ensembl chr 3:128,969,817...129,028,317 		JBrowse link
G ITGA3 integrin subunit alpha 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23595732) Ensembl
MGI		 PMID:23595732 GO_REF:0000107 NCBI chr17:44,145,974...44,181,343
Ensembl chr17:49,019,892...49,055,245 		JBrowse link
G ITGB1 integrin subunit beta 1 acts_upstream_of_or_within ISO (PMID:22357865) MGI PMID:22357865 NCBI chr10:33,023,573...33,081,384
Ensembl chr10:33,608,978...33,644,031 		JBrowse link
G KANK1 KN motif and ankyrin repeat domains 1 involved_in ISO (PMID:18458160) UniProt PMID:18458160 NCBI chr 9:550,713...556,230 JBrowse link
G KCTD10 potassium channel tetramerization domain containing 10 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:107,025,380...107,054,118
Ensembl chr12:110,419,859...110,448,773 		JBrowse link
G KCTD13 potassium channel tetramerization domain containing 13 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118
G LOC100981597 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:43,451,160...43,452,331 JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:108,646,278...108,772,238
Ensembl chr 7:121,365,438...121,468,159 		JBrowse link
G MYOC myocilin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:147,128,541...147,146,227
Ensembl chr 1:150,841,630...150,858,628 		JBrowse link
G RASIP1 Ras interacting protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:45,720,179...45,740,131 JBrowse link
G RIPOR1 RHO family interacting cell polarization regulator 1 involved_in ISO (PMID:25588844) UniProt PMID:25588844 NCBI chr16:47,872,769...47,890,776
Ensembl chr16:67,268,180...67,278,445 		JBrowse link
G RIPOR2 RHO family interacting cell polarization regulator 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:24,642,239...24,768,074
Ensembl chr 6:24,973,412...25,204,745 		JBrowse link
G SCAI suppressor of cancer cell invasion involved_in IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107 NCBI chr 9:96,063,149...96,264,502
Ensembl chr 9:124,589,616...124,780,072 		JBrowse link
G STMN1 stathmin 1 involved_in ISO (PMID:25198505) CAFA PMID:25198505 NCBI chr 1:25,159,241...25,165,535
Ensembl chr 1:26,208,731...26,230,925 		JBrowse link
G TNFAIP1 TNF alpha induced protein 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:28,427,448...28,438,826
Ensembl chr17:28,929,788...28,941,278 		JBrowse link
G TNS3 tensin 3 acts_upstream_of_or_within ISO (PMID:27505886) MGI PMID:27505886 NCBI chr 7:47,915,668...48,223,267
Ensembl chr 7:48,025,720...48,221,437 		JBrowse link
positive regulation of Rho protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABRA actin binding Rho activating protein involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:103,399,433...103,410,184
Ensembl chr 8:105,546,026...105,556,777 		JBrowse link
G ADGRG1 adhesion G protein-coupled receptor G1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:37,896,177...37,942,040
Ensembl chr16:57,036,425...57,074,221 		JBrowse link
G AKAP13 A-kinase anchoring protein 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:64,076,422...64,438,109
Ensembl chr15:83,387,667...83,651,362 		JBrowse link
G APOA1 apolipoprotein A1 involved_in ISO (PMID:23726972) UniProt PMID:23726972 NCBI chr11:111,673,539...111,675,428
Ensembl chr11:115,606,136...115,608,122 		JBrowse link
G ARHGEF3 Rho guanine nucleotide exchange factor 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:56,663,382...57,012,955
Ensembl chr 3:57,878,054...58,179,339 		JBrowse link
G ARRB1 arrestin beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:70,319,935...70,411,276
Ensembl chr11:73,630,276...73,654,155 		JBrowse link
G COL3A1 collagen type III alpha 1 chain involved_in ISO (MGI:5288127|PMID:21768377) UniProt PMID:21768377 MGI:5288127 NCBI chr2B:76,285,115...76,322,703
Ensembl chr2B:194,204,613...194,242,956 		JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:144,919,775...144,977,105
Ensembl chr 5:150,929,420...150,985,912 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:17,560,337...17,600,808
Ensembl chr17:17,777,434...17,805,862 		JBrowse link
G F11R F11 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:136,399,766...136,424,722
Ensembl chr 1:140,324,943...140,346,890 		JBrowse link
G F2R coagulation factor II thrombin receptor involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:38,462,521...38,478,882
Ensembl chr 5:39,110,170...39,129,688
Ensembl chr 5:39,110,170...39,129,688 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118
G F2RL2 coagulation factor II thrombin receptor like 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:38,680,372...38,688,509
Ensembl chr 5:39,297,424...39,305,370 		JBrowse link
G F2RL3 F2R like thrombin or trypsin receptor 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:16,375,572...16,379,587
Ensembl chr19:17,355,542...17,357,628 		JBrowse link
G GPR17 G protein-coupled receptor 17 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2B:32,623,444...32,630,256
Ensembl chr2B:128,316,464...128,321,519 		JBrowse link
G GPR174 G protein-coupled receptor 174 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:68,284,983...68,286,466
Ensembl chr  X:78,395,005...78,396,006 		JBrowse link
G GPR18 G protein-coupled receptor 18 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:80,423,534...80,427,604
Ensembl chr13:99,562,589...99,563,584 		JBrowse link
G GPR20 G protein-coupled receptor 20 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:138,024,139...138,037,886
Ensembl chr 8:141,108,910...141,109,986 		JBrowse link
G GPR35 G protein-coupled receptor 35 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2B:127,853,660...127,887,204
Ensembl chr2B:246,680,998...246,692,090 		JBrowse link
G GPR4 G protein-coupled receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:42,594,996...42,608,032
Ensembl chr19:51,137,138...51,138,226 		JBrowse link
G GPR55 G protein-coupled receptor 55 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr2B:118,159,511...118,163,334
Ensembl chr2B:236,958,210...236,959,169 		JBrowse link
G ITSN1 intersectin 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:20,009,385...20,266,835
Ensembl chr21:33,457,081...33,625,248 		JBrowse link
G ITSN2 intersectin 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2A:24,199,600...24,354,314
Ensembl chr2A:24,297,373...24,419,593 		JBrowse link
G LPAR1 lysophosphatidic acid receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15755723) Ensembl
MGI		 PMID:15755723 GO_REF:0000107 NCBI chr 9:82,013,960...82,179,227
Ensembl chr 9:110,179,600...110,279,038 		JBrowse link
G LPAR2 lysophosphatidic acid receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15755723) Ensembl
MGI		 PMID:15755723 GO_REF:0000107 NCBI chr19:19,060,927...19,065,792
Ensembl chr19:20,057,179...20,061,260 		JBrowse link
G LPAR6 lysophosphatidic acid receptor 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:29,561,219...29,567,414
Ensembl chr13:48,263,254...48,264,291 		JBrowse link
G MCF2L MCF.2 cell line derived transforming sequence like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:94,024,030...94,239,491
Ensembl chr13:113,111,066...113,309,224 		JBrowse link
G NET1 neuroepithelial cell transforming 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:5,457,920...5,503,223
Ensembl chr10:5,444,127...5,489,509 		JBrowse link
G NGFR nerve growth factor receptor ISO RGD PMID:18786176 RGD:5508741 NCBI chr17:8,089,600...8,109,361
Ensembl chr17:8,075,316...8,094,966 		JBrowse link
G P2RY8 P2Y receptor family member 8 involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr  X:1,599,411...1,600,490 JBrowse link
G PDGFRB platelet derived growth factor receptor beta ISO RGD PMID:18561944 RGD:10449505 NCBI chr 5:145,538,330...145,580,312
Ensembl chr 5:151,543,891...151,585,530 		JBrowse link
G PLXNB1 plexin B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:48,325,892...48,352,128
Ensembl chr 3:49,408,666...49,434,913 		JBrowse link
G PRAG1 PEAK1 related, kinase-activating pseudokinase 1 involved_in ISO PMID:16481321 UniProt PMID:16481321 RGD:11555369 NCBI chr 8:10,824,887...10,896,058 JBrowse link
G ROBO1 roundabout guidance receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:78,707,802...79,876,519
Ensembl chr 3:80,581,388...81,569,308 		JBrowse link
G RTN4R reticulon 4 receptor involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 Ensembl chr22:18,673,548...18,680,017 JBrowse link
G SEMA4D semaphorin 4D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:60,451,420...60,588,519
Ensembl chr 9:88,497,528...88,560,811 		JBrowse link
G SYNPO2L synaptopodin 2 like involved_in ISO (MGI:6102963|PMID:29206857) BHF-UCL PMID:29206857 MGI:6102963 NCBI chr10:70,192,289...70,204,008
Ensembl chr10:72,648,952...72,660,184 		JBrowse link
G TEK TEK receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:26,955,339...27,077,809
Ensembl chr 9:27,561,421...27,683,572 		JBrowse link
regulation of Cdc42 protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:75,948,831...76,096,136
Ensembl chr 9:104,076,516...104,224,188 		JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:101,834,189...102,005,811
Ensembl chr 9:130,484,333...130,652,941 		JBrowse link
G APOA1 apolipoprotein A1 involved_in ISO (PMID:16443932) BHF-UCL PMID:16443932 NCBI chr11:111,673,539...111,675,428
Ensembl chr11:115,606,136...115,608,122 		JBrowse link
G APOC3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:111,667,816...111,670,861
Ensembl chr11:115,600,416...115,603,460 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G NRP1 neuropilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:33,298,918...33,456,466
Ensembl chr10:33,883,173...34,039,648 		JBrowse link
G RALBP1 ralA binding protein 1 involved_in ISO PMID:7623849 UniProt PMID:7623849 RGD:633902 NCBI chr18:4,747,555...4,810,710
Ensembl chr18:7,028,188...7,090,934 		JBrowse link
G RIT2 Ras like without CAAX 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:36,008,302...36,381,259
Ensembl chr18:39,557,814...39,930,393 		JBrowse link
regulation of Rho protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKAP13 A-kinase anchoring protein 13 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:64,076,422...64,438,109
Ensembl chr15:83,387,667...83,651,362 		JBrowse link
G ARHGAP20 Rho GTPase activating protein 20 involved_in IEA InterPro GO_REF:0000002 NCBI chr11:105,457,931...105,593,644
Ensembl chr11:109,289,419...109,437,294 		JBrowse link
G ARHGDIA Rho GDP dissociation inhibitor alpha involved_in ISO (PMID:8262133) UniProt PMID:8262133 NCBI chr17:76,273,196...76,276,942
Ensembl chr17:81,975,340...81,978,447 		JBrowse link
G ARHGDIB Rho GDP dissociation inhibitor beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:14,944,746...14,964,357
Ensembl chr12:15,341,491...15,361,160 		JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15996550) TreeGrafter
MGI		 PMID:15996550 GO_REF:0000118 NCBI chr 1:131,282,514...131,326,535
Ensembl chr 1:135,112,040...135,159,299 		JBrowse link
G ARHGEF28 Rho guanine nucleotide exchange factor 28 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:41,376,631...41,690,868
Ensembl chr 5:41,976,692...42,231,634 		JBrowse link
G BCR BCR activator of RhoGEF and GTPase involved_in ISO (PMID:23940119) UniProt PMID:23940119
G CDC42SE1 CDC42 small effector 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:126,400,094...126,408,769
Ensembl chr 1:130,047,765...130,056,447 		JBrowse link
G CDC42SE2 CDC42 small effector 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:126,689,882...126,827,208
Ensembl chr 5:132,954,110...132,989,170 		JBrowse link
G CDH2 cadherin 2 ISO RGD PMID:16515795 RGD:1582675 NCBI chr18:21,210,001...21,435,919
Ensembl chr18:24,812,019...25,008,325 		JBrowse link
G DLC1 DLC1 Rho GTPase activating protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:12,282,190...12,809,770
Ensembl chr 8:9,037,742...9,460,233 		JBrowse link
G EPS8 EGFR pathway substrate 8, signaling adaptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:15,617,536...15,788,537
Ensembl chr12:16,013,276...16,076,117 		JBrowse link
G EPS8L1 EPS8 signaling adaptor L1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:52,114,011...52,125,981
Ensembl chr19:60,803,996...60,819,833 		JBrowse link
G EPS8L2 EPS8 signaling adaptor L2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:720,528...741,623
Ensembl chr11:765,689...787,128 		JBrowse link
G FLOT1 flotillin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19458231) Ensembl
MGI		 PMID:19458231 GO_REF:0000107 NCBI chr 6:30,472,839...30,487,809
Ensembl chr 6:31,342,033...31,357,559 		JBrowse link
G KANK1 KN motif and ankyrin repeat domains 1 involved_in ISO (PMID:25961457) UniProt PMID:25961457 NCBI chr 9:550,713...556,230 JBrowse link
G KANK2 KN motif and ankyrin repeat domains 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:10,713,582...10,746,371
Ensembl chr19:11,426,149...11,457,359 		JBrowse link
G MYO9B myosin IXB involved_in ISO (PMID:26529257) UniProt PMID:26529257 NCBI chr19:16,563,005...16,700,312 JBrowse link
G MYO9B myosin IXB involved_in IEA Ensembl GO_REF:0000107 Ensembl chr19:17,562,568...17,674,279 JBrowse link
G NCK2 NCK adaptor protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2A:95,939,197...96,089,163
Ensembl chr2A:106,898,547...106,976,363 		JBrowse link
G OPHN1 oligophrenin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:57,288,297...57,674,685
Ensembl chr  X:67,359,364...67,739,114 		JBrowse link
G PDCD10 programmed cell death 10 NOT|involved_in ISO (PMID:20332113) UniProt PMID:20332113 NCBI chr 3:164,703,909...164,755,085
Ensembl chr 3:172,760,923...172,811,430 		JBrowse link
G STARD13 StAR related lipid transfer domain containing 13 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:14,359,252...14,607,742
Ensembl chr13:32,789,587...33,038,606 		JBrowse link
G STARD8 StAR related lipid transfer domain containing 8 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:57,890,362...57,968,391
Ensembl chr  X:67,954,883...68,031,958 		JBrowse link
G TAGAP T cell activation RhoGTPase activating protein involved_in IEA InterPro GO_REF:0000002 NCBI chr 6:156,923,859...156,934,714
Ensembl chr 6:161,938,457...161,949,158 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16313
    cellular process 15397
      signal transduction 5399
        intracellular signal transduction 2589
          intracellular signaling cassette 1812
            small GTPase-mediated signal transduction 444
              Rho protein signal transduction 135
                Cdc42 protein signal transduction + 15
                negative regulation of Rho protein signal transduction 26
                positive regulation of Rho protein signal transduction 38
                regulation of Rho protein signal transduction + 93
Path 2
Term Annotations click to browse term
  biological_process 16313
    biological regulation 11327
      regulation of biological process 10982
        signaling 5900
          signal transduction 5399
            intracellular signal transduction 2589
              intracellular signaling cassette 1812
                small GTPase-mediated signal transduction 444
                  Rho protein signal transduction 135
                    Cdc42 protein signal transduction + 15
                    negative regulation of Rho protein signal transduction 26
                    positive regulation of Rho protein signal transduction 38
                    regulation of Rho protein signal transduction + 93
paths to the root