NCKAP1 (NCK associated protein 1) - Rat Genome Database

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Gene: NCKAP1 (NCK associated protein 1) Pan paniscus
Analyze
Symbol: NCKAP1
Name: NCK associated protein 1
RGD ID: 11995242
Description: ENCODES a protein that exhibits small GTPase binding (inferred); INVOLVED IN apical protein localization (inferred); basal protein localization (inferred); cell migration (inferred); PARTICIPATES IN E-cadherin signaling pathway; platelet-derived growth factor signaling pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic density (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nck-associated protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21385,580,366 - 85,697,222 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B85,595,344 - 85,712,200 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B70,193,950 - 70,308,442 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B188,003,235 - 188,116,704 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B188,003,235 - 188,116,710 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NCKAP1Bonoboautism spectrum disorder  ISONCKAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Autism spectrum disorderClinVarPMID:25741868
NCKAP1Bonoboautistic disorder  ISONCKAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Autistic behaviorClinVarPMID:25741868 and PMID:33157009
NCKAP1Bonobodevelopmental and epileptic encephalopathy 11  ISONCKAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Complex neurodevelopmental disorderClinVarPMID:25741868 more ...
NCKAP1BonoboDevelopmental Disabilities  ISONCKAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Global developmental delayClinVarPMID:25741875
NCKAP1Bonobogenetic disease  ISONCKAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 more ...
NCKAP1Bonoboimmunodeficiency 72  ISONCKAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Immunodeficiency 72 with autoinflammationClinVarPMID:25741868
NCKAP1Bonobointellectual disability  ISONCKAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 
NCKAP1BonoboNeurodevelopmental Disorders  ISONCKAP1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...


Biological Process
1 to 20 of 29 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NCKAP1Bonoboapical protein localization acts_upstream_of_or_withinIEAUniProtKB:P28660 and ensembl:ENSMUSP00000028386150520179 EnsemblGO_REF:0000107
NCKAP1Bonobobasal protein localization acts_upstream_of_or_withinIEAUniProtKB:P28660 and ensembl:ENSMUSP00000028386150520179 EnsemblGO_REF:0000107
NCKAP1Bonobocell migration involved_inIEAPANTHER:PTN000250328 and PANTHER:PTN008533121150520179 TreeGrafterGO_REF:0000118
NCKAP1Bonobocell migration involved in gastrulation acts_upstream_of_or_withinIEAUniProtKB:P28660 and ensembl:ENSMUSP00000028386150520179 EnsemblGO_REF:0000107
NCKAP1Bonobocell morphogenesis involved_inIEAPANTHER:PTN000250328 and PANTHER:PTN008533121150520179 TreeGrafterGO_REF:0000118
NCKAP1Bonobocell projection assembly involved_inIEAPANTHER:PTN000250328 and PANTHER:PTN008533121150520179 TreeGrafterGO_REF:0000118
NCKAP1Bonobocortical actin cytoskeleton organization involved_inIEAPANTHER:PTN000250328 and PANTHER:PTN008533121150520179 TreeGrafterGO_REF:0000118
NCKAP1Bonoboembryonic body morphogenesis acts_upstream_of_or_withinIEAUniProtKB:P28660 and ensembl:ENSMUSP00000028386150520179 EnsemblGO_REF:0000107
NCKAP1Bonoboembryonic foregut morphogenesis acts_upstream_of_or_withinIEAUniProtKB:P28660 and ensembl:ENSMUSP00000028386150520179 EnsemblGO_REF:0000107
NCKAP1Bonoboembryonic heart tube development acts_upstream_of_or_withinIEAUniProtKB:P28660 and ensembl:ENSMUSP00000028386150520179 EnsemblGO_REF:0000107
NCKAP1Bonoboendoderm development acts_upstream_of_or_withinIEAUniProtKB:P28660 and ensembl:ENSMUSP00000028386150520179 EnsemblGO_REF:0000107
NCKAP1Bonoboestablishment or maintenance of actin cytoskeleton polarity acts_upstream_of_or_withinIEAUniProtKB:P28660 and ensembl:ENSMUSP00000028386150520179 EnsemblGO_REF:0000107
NCKAP1Bonoboin utero embryonic development acts_upstream_of_or_withinIEAUniProtKB:P28660 and ensembl:ENSMUSP00000028386150520179 EnsemblGO_REF:0000107
NCKAP1Bonobolamellipodium assembly acts_upstream_of_or_withinIEAUniProtKB:P28660 and ensembl:ENSMUSP00000028386150520179 EnsemblGO_REF:0000107
NCKAP1Bonobomesodermal cell migration acts_upstream_of_or_withinIEAUniProtKB:P28660 and ensembl:ENSMUSP00000028386150520179 EnsemblGO_REF:0000107
NCKAP1Bonoboneural tube closure acts_upstream_of_or_withinIEAUniProtKB:P28660 and ensembl:ENSMUSP00000028386150520179 EnsemblGO_REF:0000107
NCKAP1Bonoboneuron projection morphogenesis involved_inIEAPANTHER:PTN000250328 and PANTHER:PTN008533121150520179 TreeGrafterGO_REF:0000118
NCKAP1Bonobonotochord development acts_upstream_of_or_withinIEAUniProtKB:P28660 and ensembl:ENSMUSP00000028386150520179 EnsemblGO_REF:0000107
NCKAP1Bonobonotochord morphogenesis acts_upstream_of_or_withinIEAUniProtKB:P28660 and ensembl:ENSMUSP00000028386150520179 EnsemblGO_REF:0000107
NCKAP1Bonoboparaxial mesoderm development acts_upstream_of_or_withinIEAUniProtKB:P28660 and ensembl:ENSMUSP00000028386150520179 EnsemblGO_REF:0000107
1 to 20 of 29 rows

Cellular Component
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NCKAP1Bonobocell projection located_inIEAUniProtKB-KW:KW-0966150520179 UniProtGO_REF:0000043
NCKAP1Bonobofilamentous actin part_ofIEAUniProtKB:P28660 and ensembl:ENSMUSP00000028386150520179 EnsemblGO_REF:0000107
NCKAP1Bonoboglutamatergic synapse is_active_inISONckap1 (Rattus norvegicus)9068941PMID:25293574SynGOPMID:25293574 and REF_RGD_ID:405650371
NCKAP1Bonobolamellipodium located_inIEAUniProtKB:P28660 and ensembl:ENSMUSP00000028386150520179 EnsemblGO_REF:0000107
NCKAP1Bonobolamellipodium membrane located_inIEAUniProtKB-SubCell:SL-0292150520179 UniProtGO_REF:0000044
NCKAP1Bonobomembrane located_inIEAUniProtKB-KW:KW-0472150520179 UniProtGO_REF:0000043
NCKAP1Bonoboplasma membrane located_inIEAUniProtKB-KW:KW-1003150520179 UniProtGO_REF:0000043
NCKAP1Bonobopostsynapse is_active_inIEAUniProtKB:P28660 and ensembl:ENSMUSP00000028386150520179 EnsemblGO_REF:0000107
NCKAP1Bonobopostsynaptic density is_active_inISONckap1 (Rattus norvegicus)9068941PMID:25293574SynGOPMID:25293574 and REF_RGD_ID:405650371
NCKAP1Bonoboruffle located_inIEAUniProtKB:P28660 and ensembl:ENSMUSP00000028386150520179 EnsemblGO_REF:0000107
NCKAP1BonoboSCAR complex part_ofIEAUniProtKB:Q9Y2A7 and ensembl:ENSP00000355348150520179 EnsemblGO_REF:0000107
NCKAP1BonoboSCAR complex part_ofIEAPANTHER:PTN000250328 and PANTHER:PTN008533121150520179 TreeGrafterGO_REF:0000118
1 to 12 of 12 rows

Imported Annotations - PID (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NCKAP1BonoboE-cadherin signaling pathway  ISONCKAP1 (Homo sapiens)9068941 PIDPID:200124 and PID:200182
NCKAP1Bonoboplatelet-derived growth factor signaling pathway  ISONCKAP1 (Homo sapiens)9068941 PIDPID:200149
PMID:30032202  



NCKAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21385,580,366 - 85,697,222 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B85,595,344 - 85,712,200 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B70,193,950 - 70,308,442 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B188,003,235 - 188,116,704 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B188,003,235 - 188,116,710 (-)Ensemblpanpan1.1panPan2
NCKAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382182,909,115 - 183,038,457 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2182,909,115 - 183,038,858 (-)EnsemblGRCh38hg38GRCh38
GRCh372183,773,843 - 183,903,185 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362183,497,850 - 183,611,474 (-)NCBINCBI36Build 36hg18NCBI36
Build 342183,615,110 - 183,728,735NCBI
Celera2177,385,839 - 177,499,386 (-)NCBICelera
Cytogenetic Map2q32.1NCBI
HuRef2175,647,499 - 175,761,404 (-)NCBIHuRef
CHM1_12183,795,489 - 183,909,486 (-)NCBICHM1_1
T2T-CHM13v2.02183,398,094 - 183,527,479 (-)NCBIT2T-CHM13v2.0
Nckap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39280,330,856 - 80,411,526 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl280,330,856 - 80,411,724 (-)EnsemblGRCm39 Ensembl
GRCm38280,500,512 - 80,581,182 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl280,500,512 - 80,581,380 (-)EnsemblGRCm38mm10GRCm38
MGSCv37280,341,452 - 80,421,122 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36280,302,134 - 80,381,804 (-)NCBIMGSCv36mm8
Celera282,167,966 - 82,247,538 (-)NCBICelera
Cytogenetic Map2C3NCBI
cM Map248.21NCBI
Nckap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8385,824,333 - 85,898,748 (-)NCBIGRCr8
mRatBN7.2365,417,450 - 65,491,769 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl365,417,453 - 65,492,217 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx368,763,734 - 68,838,101 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0377,347,303 - 77,421,669 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0375,110,005 - 75,184,226 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0367,725,180 - 67,804,680 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl367,725,947 - 67,787,990 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0374,284,277 - 74,361,208 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4363,191,700 - 63,274,021 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1363,099,188 - 63,170,297 (-)NCBI
Celera364,863,664 - 64,938,000 (-)NCBICelera
Cytogenetic Map3q24NCBI
Nckap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540314,480,162 - 14,554,702 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540314,476,689 - 14,554,380 (+)NCBIChiLan1.0ChiLan1.0
NCKAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13625,965,243 - 26,054,775 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3625,965,938 - 26,054,760 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3625,862,726 - 25,966,235 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03626,119,068 - 26,222,536 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3626,119,080 - 26,222,514 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13626,245,261 - 26,348,621 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03626,176,339 - 26,279,633 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03626,318,225 - 26,421,624 (-)NCBIUU_Cfam_GSD_1.0
Nckap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303142,971,863 - 143,070,930 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650911,524,556 - 11,624,621 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650911,525,764 - 11,624,833 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NCKAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1588,425,142 - 88,528,326 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11588,425,861 - 88,528,417 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21597,930,698 - 98,032,893 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NCKAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11068,434,839 - 68,546,431 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1068,433,258 - 68,545,990 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040130,996,820 - 131,108,402 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nckap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248444,676,741 - 4,773,538 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248444,679,840 - 4,773,617 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






Ensembl Acc Id: ENSPPAT00000062802   ⟹   ENSPPAP00000039890
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B188,003,235 - 188,116,710 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000062812   ⟹   ENSPPAP00000039900
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B188,003,235 - 188,116,710 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000062832   ⟹   ENSPPAP00000039919
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B188,004,050 - 188,116,619 (-)Ensembl
RefSeq Acc Id: XM_003823525   ⟹   XP_003823573
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21385,580,366 - 85,697,222 (-)NCBI
NHGRI_mPanPan12B85,595,344 - 85,712,200 (-)NCBI
Mhudiblu_PPA_v02B70,193,950 - 70,308,046 (-)NCBI
PanPan1.12B188,003,235 - 188,116,704 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003823526   ⟹   XP_003823574
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21385,580,366 - 85,697,222 (-)NCBI
NHGRI_mPanPan12B85,595,344 - 85,712,200 (-)NCBI
Mhudiblu_PPA_v02B70,193,956 - 70,308,442 (-)NCBI
PanPan1.12B188,003,235 - 188,116,619 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034954612   ⟹   XP_034810503
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21385,580,366 - 85,697,067 (-)NCBI
NHGRI_mPanPan12B85,595,344 - 85,711,980 (-)NCBI
Mhudiblu_PPA_v02B70,193,952 - 70,307,814 (-)NCBI
RefSeq Acc Id: XM_034954614   ⟹   XP_034810505
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21385,580,366 - 85,697,092 (-)NCBI
NHGRI_mPanPan12B85,595,344 - 85,711,980 (-)NCBI
Mhudiblu_PPA_v02B70,193,952 - 70,307,814 (-)NCBI
RefSeq Acc Id: XM_063595233   ⟹   XP_063451303
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21385,580,366 - 85,663,098 (-)NCBI
Protein RefSeqs XP_003823573 (Get FASTA)   NCBI Sequence Viewer  
  XP_003823574 (Get FASTA)   NCBI Sequence Viewer  
  XP_034810503 (Get FASTA)   NCBI Sequence Viewer  
  XP_034810505 (Get FASTA)   NCBI Sequence Viewer  
  XP_063451303 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000039890.1
  ENSPPAP00000039900.1
  ENSPPAP00000039919.1
RefSeq Acc Id: XP_003823573   ⟸   XM_003823525
- Peptide Label: isoform X3
- UniProtKB: A0A2R9CD88 (UniProtKB/TrEMBL),   A0A2R9CDG5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003823574   ⟸   XM_003823526
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CD78 (UniProtKB/TrEMBL),   A0A2R9CDG5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034810505   ⟸   XM_034954614
- Peptide Label: isoform X4
- UniProtKB: A0A2R9CDG5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034810503   ⟸   XM_034954612
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CDG5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000039890   ⟸   ENSPPAT00000062802



1 to 13 of 13 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSPPAG00000042498 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000062802.1 UniProtKB/TrEMBL
  ENSPPAT00000062812.1 UniProtKB/TrEMBL
  ENSPPAT00000062832.1 UniProtKB/TrEMBL
InterPro Nck-associated_protein-1 UniProtKB/TrEMBL
KEGG Report pps:100979519 UniProtKB/TrEMBL
NCBI Gene NCKAP1 ENTREZGENE
PANTHER NCK-ASSOCIATED PROTEIN 1 UniProtKB/TrEMBL
  PTHR12093 UniProtKB/TrEMBL
Pfam Nckap1 UniProtKB/TrEMBL
UniProt A0A2R9CD78 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CD88 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CDG5 ENTREZGENE, UniProtKB/TrEMBL
1 to 13 of 13 rows