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Gene: NCK1 (NCK adaptor protein 1) Homo sapiens

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Symbol:

NCK1

Name:

NCK adaptor protein 1

RGD ID:

1321736

HGNC Page

HGNC:7664

Description:

Enables several functions, including eukaryotic initiation factor eIF2 binding activity; molecular condensate scaffold activity; and receptor tyrosine kinase binding activity. Involved in several processes, including antiviral innate immune response; regulation of gene expression; and regulation of signal transduction. Located in several cellular components, including cytosol; endoplasmic reticulum; and ribosome. Part of protein phosphatase type 1 complex. Is active in cytoplasm.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

cytoplasmic protein NCK1; melanoma NCK protein; MGC12668; NCK; NCK adapter protein 1; NCK tyrosine kinase; nck-1; NCKalpha; non-catalytic region of tyrosine kinase; SH2/SH3 adapter protein NCK-alpha; SH2/SH3 adapter protein NCK1; SH2/SH3 adaptor protein NCK-alpha

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Nck1 (non-catalytic region of tyrosine kinase adaptor protein 1)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Nck1 (NCK adaptor protein 1)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Treefam
Chinchilla lanigera (long-tailed chinchilla):	Nck1 (NCK adaptor protein 1)	NCBI	Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):	NCK1 (NCK adaptor protein 1)	NCBI	Ortholog
Canis lupus familiaris (dog):	NCK1 (NCK adaptor protein 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, PhylomeDB, Treefam
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nck1 (NCK adaptor protein 1)	NCBI	Ortholog
Sus scrofa (pig):	NCK1 (NCK adaptor protein 1)	HGNC	EggNOG, Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Chlorocebus sabaeus (green monkey):	NCK1 (NCK adaptor protein 1)	NCBI	Ortholog
Heterocephalus glaber (naked mole-rat):	Nck1 (NCK adaptor protein 1)	NCBI	Ortholog
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Nck1 (NCK adaptor protein 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Nck1 (non-catalytic region of tyrosine kinase adaptor protein 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	nck1b (NCK adaptor protein 1b)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Danio rerio (zebrafish):	nck1a (NCK adaptor protein 1a)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|ZFIN)
Caenorhabditis elegans (roundworm):	nck-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	dock	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	nck1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus laevis (African clawed frog):	nck1.S	Alliance	DIOPT (Xenbase)
Xenopus laevis (African clawed frog):	nck1.L	Alliance	DIOPT (Xenbase)

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	136,862,208 - 136,951,606 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	136,862,208 - 136,951,606 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	136,581,050 - 136,670,448 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	138,063,763 - 138,150,658 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	138,063,770 - 138,150,665	NCBI
Celera	3	135,007,352 - 135,094,246 (+)	NCBI		Celera
Cytogenetic Map	3	q22.3	NCBI
HuRef	3	133,957,144 - 134,043,755 (+)	NCBI		HuRef
CHM1_1	3	136,544,712 - 136,631,607 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	139,602,861 - 139,692,274 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NCK1	Human	Primary Lymphedema with Myelodysplasia		IAGP	RGD:150337922	8554872	ClinVar Annotator: match by term: Emberger syndrome	ClinVar	PMID:22147895\|PMID:25741868

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NCK1	Human	Albuminuria		EXP		11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:19443634
NCK1	Human	nephrotic syndrome		EXP		11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:19443634
NCK1	Human	proteinuria		EXP		11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:19443634

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NCK1	Human	(-)-epigallocatechin 3-gallate	multiple interactions	EXP		6480464	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of NCK1 mRNA	CTD	PMID:22079256
NCK1	Human	1,2-dimethylhydrazine	decreases expression	ISO	RGD:1321737	6480464	1,2-Dimethylhydrazine results in decreased expression of NCK1 mRNA	CTD	PMID:22206623
NCK1	Human	14-Deoxy-11,12-didehydroandrographolide	increases expression	EXP		6480464	14-deoxy-11,12-didehydroandrographolide results in increased expression of NCK1 mRNA	CTD	PMID:22101062
NCK1	Human	17beta-estradiol	increases expression	ISO	RGD:1321737	6480464	Estradiol results in increased expression of NCK1 mRNA	CTD	PMID:39298647
NCK1	Human	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	RGD:1321737	6480464	Tetrachlorodibenzodioxin affects the expression of NCK1 mRNA	CTD	PMID:21570461
NCK1	Human	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	ISO	RGD:1310688	6480464	Tetrachlorodibenzodioxin results in decreased expression of NCK1 mRNA	CTD	PMID:33387578
NCK1	Human	2,4-dinitrotoluene	affects expression	ISO	RGD:1310688	6480464	2,4-dinitrotoluene affects the expression of NCK1 mRNA	CTD	PMID:21346803
NCK1	Human	2-methylcholine	affects expression	EXP		6480464	beta-methylcholine affects the expression of NCK1 mRNA	CTD	PMID:21179406
NCK1	Human	3,4-methylenedioxymethamphetamine	decreases expression	ISO	RGD:1321737	6480464	N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of NCK1 mRNA	CTD	PMID:26251327
NCK1	Human	3,4-methylenedioxymethamphetamine	increases methylation	ISO	RGD:1321737	6480464	N-Methyl-3,4-methylenedioxyamphetamine results in increased methylation of NCK1 promoter	CTD	PMID:26251327
NCK1	Human	4,4'-diaminodiphenylmethane	decreases expression	ISO	RGD:1321737	6480464	4,4'-diaminodiphenylmethane results in decreased expression of NCK1 mRNA	CTD	PMID:18648102
NCK1	Human	4,4'-sulfonyldiphenol	increases expression	ISO	RGD:1321737	6480464	bisphenol S results in increased expression of NCK1 mRNA	CTD	PMID:39298647
NCK1	Human	4-hydroxynon-2-enal	decreases expression	EXP		6480464	4-hydroxy-2-nonenal results in decreased expression of NCK1 mRNA	CTD	PMID:12419474
NCK1	Human	5-aza-2'-deoxycytidine	increases expression	EXP		6480464	Decitabine results in increased expression of NCK1 mRNA	CTD	PMID:20678512
NCK1	Human	5-aza-2'-deoxycytidine	multiple interactions	EXP		6480464	[Decitabine co-treated with trichostatin A] results in increased expression of NCK1 mRNA	CTD	PMID:20678512
NCK1	Human	all-trans-retinoic acid	decreases expression	EXP		6480464	Tretinoin results in decreased expression of NCK1 mRNA	CTD	PMID:15498508
NCK1	Human	aristolochic acid A	decreases expression	EXP		6480464	aristolochic acid I results in decreased expression of NCK1 mRNA	CTD	PMID:33212167
NCK1	Human	aristolochic acid A	multiple interactions	EXP		6480464	aristolochic acid I inhibits the reaction [SLIT2 protein results in increased expression of NCK1 mRNA]; more ...	CTD	PMID:30381256
NCK1	Human	benzo[a]pyrene	decreases expression	EXP		6480464	Benzo(a)pyrene results in decreased expression of NCK1 protein	CTD	PMID:32717239
NCK1	Human	benzo[a]pyrene	decreases methylation	EXP		6480464	Benzo(a)pyrene results in decreased methylation of NCK1 5' UTR	CTD	PMID:27901495
NCK1	Human	benzo[a]pyrene	increases methylation	EXP		6480464	Benzo(a)pyrene results in increased methylation of NCK1 3' UTR; Benzo(a)pyrene results in increased methylation of more ...	CTD	PMID:27901495
NCK1	Human	benzo[a]pyrene diol epoxide I	decreases expression	EXP		6480464	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of NCK1 mRNA	CTD	PMID:19150397
NCK1	Human	bis(2-ethylhexyl) phthalate	increases expression	ISO	RGD:1321737	6480464	Diethylhexyl Phthalate results in increased expression of NCK1 mRNA	CTD	PMID:34319233
NCK1	Human	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of NCK1 mRNA	CTD	PMID:20678512
NCK1	Human	bisphenol A	increases expression	ISO	RGD:1310688	6480464	bisphenol A results in increased expression of NCK1 mRNA	CTD	PMID:25181051\|PMID:30816183\|PMID:32528016
NCK1	Human	bisphenol F	increases expression	ISO	RGD:1321737	6480464	bisphenol F results in increased expression of NCK1 mRNA	CTD	PMID:38685157
NCK1	Human	cadmium dichloride	decreases expression	EXP		6480464	Cadmium Chloride results in decreased expression of NCK1 mRNA	CTD	PMID:38568856
NCK1	Human	caffeine	increases phosphorylation	EXP		6480464	Caffeine results in increased phosphorylation of NCK1 protein	CTD	PMID:35688186
NCK1	Human	cyclosporin A	increases expression	EXP		6480464	Cyclosporine results in increased expression of NCK1 mRNA	CTD	PMID:20106945\|PMID:25562108
NCK1	Human	deguelin	increases expression	EXP		6480464	deguelin results in increased expression of NCK1 mRNA	CTD	PMID:33512557
NCK1	Human	Dibutyl phosphate	affects expression	EXP		6480464	di-n-butylphosphoric acid affects the expression of NCK1 mRNA	CTD	PMID:37042841
NCK1	Human	dicrotophos	decreases expression	EXP		6480464	dicrotophos results in decreased expression of NCK1 mRNA	CTD	PMID:28302478
NCK1	Human	Diisodecyl phthalate	increases expression	ISO	RGD:1321737	6480464	diisodecyl phthalate results in increased expression of NCK1 mRNA	CTD	PMID:25270620
NCK1	Human	ethanol	multiple interactions	EXP		6480464	[[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic more ...	CTD	PMID:29432896
NCK1	Human	folic acid	decreases expression	ISO	RGD:1321737	6480464	Folic Acid results in decreased expression of NCK1 mRNA	CTD	PMID:25629700
NCK1	Human	folpet	decreases expression	ISO	RGD:1321737	6480464	folpet results in decreased expression of NCK1 mRNA	CTD	PMID:31558096
NCK1	Human	FR900359	affects phosphorylation	EXP		6480464	FR900359 affects the phosphorylation of NCK1 protein	CTD	PMID:37730182
NCK1	Human	gentamycin	increases expression	ISO	RGD:1310688	6480464	Gentamicins results in increased expression of NCK1 mRNA	CTD	PMID:22061828
NCK1	Human	gentamycin	decreases expression	ISO	RGD:1310688	6480464	Gentamicins results in decreased expression of NCK1 mRNA	CTD	PMID:33387578
NCK1	Human	GSK-J4	increases expression	EXP		6480464	GSK-J4 results in increased expression of NCK1 mRNA	CTD	PMID:29301935
NCK1	Human	irinotecan	decreases expression	EXP		6480464	Irinotecan metabolite results in decreased expression of NCK1 mRNA; Irinotecan results in decreased expression of more ...	CTD	PMID:15956246
NCK1	Human	ivermectin	increases expression	EXP		6480464	Ivermectin results in increased expression of NCK1 protein	CTD	PMID:32959892
NCK1	Human	methotrexate	decreases expression	EXP		6480464	Methotrexate results in decreased expression of NCK1 mRNA	CTD	PMID:17400583
NCK1	Human	methoxychlor	increases methylation	ISO	RGD:1310688	6480464	Methoxychlor results in increased methylation of NCK1 gene	CTD	PMID:23303685
NCK1	Human	methyl methanesulfonate	decreases expression	EXP		6480464	Methyl Methanesulfonate results in decreased expression of NCK1 mRNA	CTD	PMID:23649840
NCK1	Human	methylmercury chloride	decreases expression	EXP		6480464	methylmercuric chloride results in decreased expression of NCK1 mRNA	CTD	PMID:28001369
NCK1	Human	paracetamol	decreases expression	ISO	RGD:1310688	6480464	Acetaminophen results in decreased expression of NCK1 mRNA	CTD	PMID:33387578
NCK1	Human	phenobarbital	affects expression	EXP		6480464	Phenobarbital affects the expression of NCK1 mRNA	CTD	PMID:19159669
NCK1	Human	phenylmercury acetate	decreases expression	EXP		6480464	Phenylmercuric Acetate results in decreased expression of NCK1 mRNA	CTD	PMID:26272509
NCK1	Human	piroxicam	decreases expression	EXP		6480464	Piroxicam results in decreased expression of NCK1 mRNA	CTD	PMID:21858171
NCK1	Human	potassium chromate	decreases expression	EXP		6480464	potassium chromate(VI) results in decreased expression of NCK1 mRNA	CTD	PMID:22079256
NCK1	Human	potassium chromate	multiple interactions	EXP		6480464	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of NCK1 mRNA	CTD	PMID:22079256
NCK1	Human	progesterone	increases expression	ISO	RGD:1310688	6480464	Progesterone results in increased expression of NCK1 mRNA	CTD	PMID:21770760
NCK1	Human	propiconazole	increases expression	ISO	RGD:1321737	6480464	propiconazole results in increased expression of NCK1 mRNA	CTD	PMID:21278054
NCK1	Human	rotenone	increases expression	EXP		6480464	Rotenone results in increased expression of NCK1 mRNA	CTD	PMID:33512557
NCK1	Human	silicon dioxide	increases expression	ISO	RGD:1321737	6480464	Silicon Dioxide results in increased expression of NCK1 mRNA	CTD	PMID:23221170
NCK1	Human	sodium arsenate	increases expression	ISO	RGD:1321737	6480464	sodium arsenate results in increased expression of NCK1 mRNA	CTD	PMID:30953684
NCK1	Human	sodium arsenite	increases expression	EXP		6480464	sodium arsenite results in increased expression of NCK1 mRNA	CTD	PMID:12016162
NCK1	Human	tamibarotene	affects expression	EXP		6480464	tamibarotene affects the expression of NCK1 mRNA	CTD	PMID:15498508
NCK1	Human	tetrachloromethane	increases expression	ISO	RGD:1321737	6480464	Carbon Tetrachloride results in increased expression of NCK1 mRNA	CTD	PMID:31919559
NCK1	Human	titanium dioxide	decreases methylation	ISO	RGD:1321737	6480464	titanium dioxide results in decreased methylation of NCK1 gene	CTD	PMID:35295148
NCK1	Human	trichostatin A	multiple interactions	EXP		6480464	[decitabine co-treated with trichostatin A] results in increased expression of NCK1 mRNA	CTD	PMID:20678512
NCK1	Human	triphenyl phosphate	affects expression	EXP		6480464	triphenyl phosphate affects the expression of NCK1 mRNA	CTD	PMID:37042841
NCK1	Human	triptonide	increases expression	ISO	RGD:1321737	6480464	triptonide results in increased expression of NCK1 mRNA	CTD	PMID:33045310
NCK1	Human	troglitazone	decreases expression	ISO	RGD:1321737	6480464	troglitazone results in decreased expression of NCK1 mRNA	CTD	PMID:28973697
NCK1	Human	valproic acid	decreases expression	EXP		6480464	Valproic Acid results in decreased expression of NCK1 mRNA	CTD	PMID:26272509\|PMID:29154799
NCK1	Human	zoledronic acid	increases expression	EXP		6480464	zoledronic acid results in increased expression of NCK1 mRNA	CTD	PMID:24714768

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NCK1	Human	actin filament organization	acts_upstream_of_or_within	IEA	UniProtKB:Q99M51\|ensembl:ENSMUSP00000112221	150520179		Ensembl	GO_REF:0000107
NCK1	Human	antiviral innate immune response	involved_in	IDA		150520179	PMID:18835251	UniProt	PMID:18835251
NCK1	Human	cell migration	involved_in	IBA	FB:FBgn0024811\|MGI:104686\|MGI:109601\|MGI:1306821\|MGI:88508\|PANTHER:PTN001072514\|WB:WBGene00000416	150520179		GO_Central	GO_REF:0000033
NCK1	Human	cell migration	acts_upstream_of_or_within	IEA	UniProtKB:Q99M51\|ensembl:ENSMUSP00000112221	150520179		Ensembl	GO_REF:0000107
NCK1	Human	ephrin receptor signaling pathway	involved_in	IBA	MGI:109601\|MGI:1306821\|PANTHER:PTN002543470	150520179		GO_Central	GO_REF:0000033
NCK1	Human	ephrin receptor signaling pathway	acts_upstream_of_or_within	IEA	UniProtKB:Q99M51\|ensembl:ENSMUSP00000112221	150520179		Ensembl	GO_REF:0000107
NCK1	Human	lamellipodium assembly	acts_upstream_of_or_within	IEA	UniProtKB:Q99M51\|ensembl:ENSMUSP00000112221	150520179		Ensembl	GO_REF:0000107
NCK1	Human	negative regulation of insulin receptor signaling pathway	involved_in	IMP		150520179	PMID:21707536	FlyBase	PMID:21707536
NCK1	Human	negative regulation of PERK-mediated unfolded protein response	involved_in	IBA	MGI:109601\|MGI:1306821\|PANTHER:PTN002543470\|UniProtKB:P16333	150520179		GO_Central	GO_REF:0000033
NCK1	Human	negative regulation of PERK-mediated unfolded protein response	involved_in	IDA		150520179	PMID:14676213	ParkinsonsUK-UCL	PMID:14676213
NCK1	Human	negative regulation of PERK-mediated unfolded protein response	involved_in	IEA	UniProtKB:Q99M51\|ensembl:ENSMUSP00000112221	150520179		Ensembl	GO_REF:0000107
NCK1	Human	negative regulation of T cell receptor signaling pathway	involved_in	IDA		150520179	PMID:38614099	UniProt	PMID:38614099
NCK1	Human	negative regulation of transcription by RNA polymerase II	involved_in	IEA	UniProtKB:Q99M51\|ensembl:ENSMUSP00000112221	150520179		Ensembl	GO_REF:0000107
NCK1	Human	negative regulation of transcription by RNA polymerase II	involved_in	IDA		150520179	PMID:16835242	ParkinsonsUK-UCL	PMID:16835242
NCK1	Human	positive regulation of actin filament polymerization	involved_in	IEA	UniRule:UR000736768	150520179		UniProt	GO_REF:0000104
NCK1	Human	positive regulation of actin filament polymerization	acts_upstream_of_or_within	IEA	UniProtKB:Q99M51\|ensembl:ENSMUSP00000112221	150520179		Ensembl	GO_REF:0000107
NCK1	Human	positive regulation of actin filament polymerization	involved_in	IMP		150520179	PMID:12110186	UniProt	PMID:12110186
NCK1	Human	positive regulation of cap-dependent translational initiation	involved_in	IDA		150520179	PMID:11959995	ParkinsonsUK-UCL	PMID:11959995
NCK1	Human	positive regulation of cap-independent translational initiation	involved_in	IDA		150520179	PMID:11959995	ParkinsonsUK-UCL	PMID:11959995
NCK1	Human	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	involved_in	IBA	MGI:109601\|MGI:1306821\|PANTHER:PTN002543470\|UniProtKB:P16333	150520179		GO_Central	GO_REF:0000033
NCK1	Human	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	involved_in	IEA	UniProtKB:Q99M51\|ensembl:ENSMUSP00000112221	150520179		Ensembl	GO_REF:0000107
NCK1	Human	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	involved_in	IDA		150520179	PMID:14676213	ParkinsonsUK-UCL	PMID:14676213
NCK1	Human	positive regulation of neuron projection development	acts_upstream_of_or_within	IEA	UniProtKB:Q99M51\|ensembl:ENSMUSP00000112221	150520179		Ensembl	GO_REF:0000107
NCK1	Human	positive regulation of T cell proliferation	involved_in	IMP		150520179	PMID:12110186	UniProt	PMID:12110186
NCK1	Human	positive regulation of transcription by RNA polymerase II	involved_in	IDA		150520179	PMID:10026169	UniProt	PMID:10026169
NCK1	Human	positive regulation of translation in response to endoplasmic reticulum stress	involved_in	IBA	MGI:109601\|MGI:1306821\|PANTHER:PTN002543470\|UniProtKB:P16333	150520179		GO_Central	GO_REF:0000033
NCK1	Human	positive regulation of translation in response to endoplasmic reticulum stress	involved_in	IDA		150520179	PMID:14676213	ParkinsonsUK-UCL	PMID:14676213
NCK1	Human	positive regulation of translation in response to endoplasmic reticulum stress	involved_in	IEA	UniProtKB:Q99M51\|ensembl:ENSMUSP00000112221	150520179		Ensembl	GO_REF:0000107
NCK1	Human	regulation of cell migration	acts_upstream_of_or_within	IEA	UniProtKB:Q99M51\|ensembl:ENSMUSP00000112221	150520179		Ensembl	GO_REF:0000107
NCK1	Human	regulation of translation	involved_in	IEA	UniProtKB-KW:KW-0810	150520179		UniProt	GO_REF:0000043
NCK1	Human	regulation of translation initiation in response to endoplasmic reticulum stress	involved_in	IEA	UniProtKB:Q99M51\|ensembl:ENSMUSP00000112221	150520179		Ensembl	GO_REF:0000107
NCK1	Human	regulation of translation initiation in response to endoplasmic reticulum stress	involved_in	IDA		150520179	PMID:14676213	ParkinsonsUK-UCL	PMID:14676213
NCK1	Human	response to endoplasmic reticulum stress	involved_in	IEA	UniProtKB:Q99M51\|ensembl:ENSMUSP00000112221	150520179		Ensembl	GO_REF:0000107
NCK1	Human	response to endoplasmic reticulum stress	involved_in	IDA		150520179	PMID:16835242	ParkinsonsUK-UCL	PMID:16835242
NCK1	Human	response to other organism	acts_upstream_of_or_within	IEA	UniProtKB:Q99M51\|ensembl:ENSMUSP00000112221	150520179		Ensembl	GO_REF:0000107
NCK1	Human	signal complex assembly	involved_in	NAS		150520179	PMID:12110186	UniProt	PMID:12110186
NCK1	Human	substrate-dependent cell migration, cell extension	acts_upstream_of_or_within	IEA	UniProtKB:Q99M51\|ensembl:ENSMUSP00000112221	150520179		Ensembl	GO_REF:0000107
NCK1	Human	T cell activation	involved_in	IMP		150520179	PMID:12110186	UniProt	PMID:12110186

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NCK1	Human	cell-cell junction	located_in	IEA	UniProtKB:Q99M51\|ensembl:ENSMUSP00000112221	150520179		Ensembl	GO_REF:0000107
NCK1	Human	cytoplasm	located_in	IEA	UniProtKB-KW:KW-0963	150520179		UniProt	GO_REF:0000043
NCK1	Human	cytoplasm	located_in	IDA		150520179	PMID:25468996	BHF-UCL	PMID:25468996
NCK1	Human	cytoplasm	located_in	NAS		150520179	PMID:12110186	UniProt	PMID:12110186
NCK1	Human	cytoplasm	is_active_in	IBA	PANTHER:PTN001072514\|UniProtKB:O43639\|UniProtKB:P16333\|UniProtKB:P46109\|WB:WBGene00006410	150520179		GO_Central	GO_REF:0000033
NCK1	Human	cytoplasm	is_active_in	IDA		150520179	PMID:38614099	UniProt	PMID:38614099
NCK1	Human	cytoplasm	located_in	IEA	UniRule:UR000736768	150520179		UniProt	GO_REF:0000104
NCK1	Human	cytoplasm	located_in	TAS		150520179	PMID:2107526	PINC	PMID:2107526
NCK1	Human	cytoplasm	located_in	IEA	UniProtKB-SubCell:SL-0086	150520179		UniProt	GO_REF:0000044
NCK1	Human	cytosol	located_in	IEA	ARBA:ARBA00029243	150520179		UniProt	GO_REF:0000117
NCK1	Human	cytosol	located_in	TAS		150520179		Reactome	Reactome:R-HSA-2029466\|Reactome:R-HSA-2197690\|Reactome:R-HSA-2197691\|Reactome:R-HSA-2197698\|Reactome:R-HSA-373716\|Reactome:R-HSA-373724\|Reactome:R-HSA-382058\|Reactome:R-HSA-418850\|Reactome:R-HSA-418856\|Reactome:R-HSA-418858\|Reactome:R-HSA-418874\|Reactome:R-HSA-430180\|Reactome:R-HSA-430183\|Reactome:R-HSA-430190\|Reactome:R-HSA-5218804\|Reactome:R-HSA-5218806\|Reactome:R-HSA-5218812\|Reactome:R-HSA-5218814\|Reactome:R-HSA-5218815\|Reactome:R-HSA-5218824\|Reactome:R-HSA-5218832\|Reactome:R-HSA-5218847\|Reactome:R-HSA-5218854\|Reactome:R-HSA-532603\|Reactome:R-HSA-9606151\|Reactome:R-HSA-9691421\|Reactome:R-HSA-9835189
NCK1	Human	cytosol	located_in	IDA		150520179		HPA	GO_REF:0000052
NCK1	Human	cytosol	located_in	IEA	UniRule:UR000736768	150520179		UniProt	GO_REF:0000104
NCK1	Human	endoplasmic reticulum	located_in	IEA	UniProtKB-SubCell:SL-0095	150520179		UniProt	GO_REF:0000044
NCK1	Human	endoplasmic reticulum	located_in	IDA		150520179	PMID:16835242	ParkinsonsUK-UCL	PMID:16835242
NCK1	Human	endoplasmic reticulum	located_in	IEA	UniRule:UR000736768	150520179		UniProt	GO_REF:0000104
NCK1	Human	endoplasmic reticulum	located_in	IEA	UniProtKB-KW:KW-0256	150520179		UniProt	GO_REF:0000043
NCK1	Human	nucleus	located_in	IEA	UniProtKB-SubCell:SL-0191	150520179		UniProt	GO_REF:0000044
NCK1	Human	nucleus	located_in	IEA	UniProtKB-KW:KW-0539	150520179		UniProt	GO_REF:0000043
NCK1	Human	plasma membrane	located_in	TAS		150520179		Reactome	Reactome:R-HSA-1112666
NCK1	Human	plasma membrane	located_in	IDA		150520179		HPA	GO_REF:0000052
NCK1	Human	protein phosphatase type 1 complex	part_of	IDA		150520179	PMID:16835242	ParkinsonsUK-UCL	PMID:16835242
NCK1	Human	ribosome	located_in	IDA		150520179	PMID:11959995	ParkinsonsUK-UCL	PMID:11959995
NCK1	Human	vesicle membrane	located_in	IEA	UniProtKB:Q99M51\|ensembl:ENSMUSP00000112221	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NCK1	Human	cadherin binding	enables	HDA		150520179	PMID:25468996	BHF-UCL	PMID:25468996
NCK1	Human	cytoskeletal anchor activity	enables	NAS		150520179	PMID:12110186	UniProt	PMID:12110186
NCK1	Human	ephrin receptor binding	enables	IBA	MGI:109601\|PANTHER:PTN002717628	150520179		GO_Central	GO_REF:0000033
NCK1	Human	ephrin receptor binding	enables	IEA	UniProtKB:Q99M51\|ensembl:ENSMUSP00000112221	150520179		Ensembl	GO_REF:0000107
NCK1	Human	eukaryotic initiation factor eIF2 binding	enables	IEA	UniProtKB:B2RZ33\|UniProtKB:Q99M51\|ensembl:ENSMUSP00000112221\|ensembl:ENSRNOP00000020330	150520179		Ensembl	GO_REF:0000107
NCK1	Human	eukaryotic initiation factor eIF2 binding	enables	IPI	UniProtKB:P20042\|UniProtKB:Q99L45	150520179	PMID:11959995	ParkinsonsUK-UCL	PMID:11959995
NCK1	Human	molecular condensate scaffold activity	enables	IDA		150520179	PMID:26553976	DisProt	PMID:26553976
NCK1	Human	protein binding	enables	IPI	UniProtKB:Q9BYB0\|UniProtKB:Q9P206	150520179	PMID:21988832	IntAct	PMID:21988832
NCK1	Human	protein binding	enables	IPI	UniProtKB:Q9ULH1	150520179	PMID:16636290	IntAct	PMID:16636290
NCK1	Human	protein binding	enables	IPI	UniProtKB:O43516	150520179	PMID:12620186	IntAct	PMID:12620186
NCK1	Human	protein binding	enables	IPI	UniProtKB:Q9UKE5	150520179	PMID:10521462	UniProt	PMID:10521462
NCK1	Human	protein binding	enables	IPI	UniProtKB:A0A0C3SFZ9\|UniProtKB:B7ZLH0\|UniProtKB:O00401\|UniProtKB:O43281-2\|UniProtKB:O60504\|UniProtKB:P48023\|UniProtKB:Q96IJ6\|UniProtKB:Q9NYB9-2	150520179	PMID:26871637	IntAct	PMID:26871637
NCK1	Human	protein binding	enables	IPI	UniProtKB:Q8WV28	150520179	PMID:9697839	UniProt	PMID:9697839
NCK1	Human	protein binding	enables	IPI	UniProtKB:O55236\|UniProtKB:O60942	150520179	PMID:25137142	IntAct	PMID:25137142
NCK1	Human	protein binding	enables	IPI	UniProtKB:Q13094	150520179	PMID:10229072, PMID:15929943, PMID:20562827, PMID:21725281, PMID:31467278	IntAct	PMID:10229072\|PMID:15929943\|PMID:20562827\|PMID:21725281\|PMID:31467278
NCK1	Human	protein binding	enables	IPI	UniProtKB:O00401	150520179	PMID:26496610	IntAct	PMID:26496610
NCK1	Human	protein binding	enables	IPI	UniProtKB:P10912\|UniProtKB:P42684	150520179	PMID:25241761	IntAct	PMID:25241761
NCK1	Human	protein binding	enables	IPI	UniProtKB:Q8N4C8	150520179	PMID:15469942	UniProt	PMID:15469942
NCK1	Human	protein binding	enables	IPI	UniProtKB:O60500	150520179	PMID:16525419	IntAct	PMID:16525419
NCK1	Human	protein binding	enables	IPI	UniProtKB:O15117	150520179	PMID:22074159	IntAct	PMID:22074159
NCK1	Human	protein binding	enables	IPI	UniProtKB:P20936	150520179	PMID:21664272	IntAct	PMID:21664272
NCK1	Human	protein binding	enables	IPI	UniProtKB:P00533\|UniProtKB:Q07889\|UniProtKB:Q13153\|UniProtKB:Q16513	150520179	PMID:10026169	UniProt	PMID:10026169
NCK1	Human	protein binding	enables	IPI	UniProtKB:Q13177	150520179	PMID:16374509	IntAct	PMID:16374509
NCK1	Human	protein binding	enables	IPI	UniProtKB:P35968	150520179	PMID:16966330	IntAct	PMID:16966330
NCK1	Human	protein binding	enables	IPI	UniProtKB:Q92918	150520179	PMID:9346925	IntAct	PMID:9346925
NCK1	Human	protein binding	enables	IPI	UniProtKB:P20963	150520179	PMID:18320063	IntAct	PMID:18320063
NCK1	Human	protein binding	enables	IPI	UniProtKB:P19525	150520179	PMID:18835251	UniProt	PMID:18835251
NCK1	Human	protein binding	enables	IPI	UniProtKB:Q13191	150520179	PMID:25218436	IntAct	PMID:25218436
NCK1	Human	protein binding	enables	IPI	UniProtKB:P07766	150520179	PMID:17617578, PMID:18955169	IntAct	PMID:17617578\|PMID:18955169
NCK1	Human	protein binding	enables	IPI	UniProtKB:O54967	150520179	PMID:16777958	IntAct	PMID:16777958
NCK1	Human	protein binding	enables	IPI	UniProtKB:P08581\|UniProtKB:P10721\|UniProtKB:Q13480	150520179	PMID:24728074	IntAct	PMID:24728074
NCK1	Human	protein binding	enables	IPI	UniProtKB:P52757\|UniProtKB:Q13177\|UniProtKB:Q5HYW2\|UniProtKB:Q6ZUJ8-3\|UniProtKB:Q9Y2H0-1	150520179	PMID:32296183	IntAct	PMID:32296183
NCK1	Human	protein binding	enables	IPI	UniProtKB:Q13285	150520179	PMID:39009827	IntAct	PMID:39009827
NCK1	Human	protein binding	enables	IPI	UniProtKB:O00401\|UniProtKB:P48023	150520179	PMID:16595635	IntAct	PMID:16595635
NCK1	Human	protein binding	enables	IPI	UniProtKB:P00533	150520179	PMID:16273093, PMID:24658140, PMID:35384245	IntAct	PMID:16273093\|PMID:24658140\|PMID:35384245
NCK1	Human	protein binding	enables	IPI	UniProtKB:Q8IZP0	150520179	PMID:11418237	IntAct	PMID:11418237
NCK1	Human	protein binding	enables	IPI	UniProtKB:Q9Y5X2	150520179	PMID:17474147	IntAct	PMID:17474147
NCK1	Human	protein binding	enables	IPI	UniProtKB:O00254\|UniProtKB:O00294\|UniProtKB:O00401\|UniProtKB:O00750\|UniProtKB:O14490\|UniProtKB:O14513\|UniProtKB:O15056\|UniProtKB:O15085\|UniProtKB:O15117\|UniProtKB:O43150\|UniProtKB:O43390\|UniProtKB:O43493\|UniProtKB:O43708\|UniProtKB:O43918\|UniProtKB:O60674\|UniProtKB:O60721\|UniProtKB:O60885\|UniProtKB:O75167\|UniProtKB:O75326\|UniProtKB:O75369\|UniProtKB:O75593\|UniProtKB:O95886\|UniProtKB:P00519\|UniProtKB:P08047\|UniProtKB:P10301\|UniProtKB:P10412\|UniProtKB:P10912\|UniProtKB:P13671\|UniProtKB:P15586\|UniProtKB:P15918\|UniProtKB:P20810\|UniProtKB:P26373\|UniProtKB:P27816\|UniProtKB:P29074\|UniProtKB:P30260\|UniProtKB:P31994\|UniProtKB:P31995\|UniProtKB:P41970\|UniProtKB:P42167\|UniProtKB:P42566\|UniProtKB:P42684\|UniProtKB:P43699\|UniProtKB:P47928\|UniProtKB:P78329\|UniProtKB:P78345\|UniProtKB:P78357\|UniProtKB:P98082\|UniProtKB:Q07889\|UniProtKB:Q07890\|UniProtKB:Q13087\|UniProtKB:Q13111\|UniProtKB:Q13285\|UniProtKB:Q13796\|UniProtKB:Q13905\|UniProtKB:Q14008\|UniProtKB:Q14118\|UniProtKB:Q15036\|UniProtKB:Q15109\|UniProtKB:Q15661\|UniProtKB:Q15746\|UniProtKB:Q8IZD9\|UniProtKB:Q8TB24\|UniProtKB:Q8WX92\|UniProtKB:Q92918\|UniProtKB:Q92988\|UniProtKB:Q96GP6\|UniProtKB:Q96NS5\|UniProtKB:Q96RL7\|UniProtKB:Q96T58\|UniProtKB:Q99259\|UniProtKB:Q9BQ89\|UniProtKB:Q9BWF2\|UniProtKB:Q9BXM0\|UniProtKB:Q9BY71\|UniProtKB:Q9BYB0\|UniProtKB:Q9H1R2\|UniProtKB:Q9H222\|UniProtKB:Q9H5I1\|UniProtKB:Q9H8V3\|UniProtKB:Q9H9L3\|UniProtKB:Q9HCM9\|UniProtKB:Q9NQ76\|UniProtKB:Q9NYQ7\|UniProtKB:Q9NZM4\|UniProtKB:Q9NZV5\|UniProtKB:Q9P1A6\|UniProtKB:Q9UBS5\|UniProtKB:Q9UHI7\|UniProtKB:Q9UIF9\|UniProtKB:Q9UKE5\|UniProtKB:Q9UL42\|UniProtKB:Q9ULD4\|UniProtKB:Q9ULH1\|UniProtKB:Q9ULW0\|UniProtKB:Q9UMN6\|UniProtKB:Q9UMY4\|UniProtKB:Q9UPX8\|UniProtKB:Q9UQ26\|UniProtKB:Q9Y2H0\|UniProtKB:Q9Y4K4	150520179	PMID:17474147	IntAct	PMID:17474147
NCK1	Human	protein binding	enables	IPI	UniProtKB:O00401\|UniProtKB:O14513\|UniProtKB:O43150\|UniProtKB:O43516\|UniProtKB:P42684\|UniProtKB:Q07889\|UniProtKB:Q07890\|UniProtKB:Q13177\|UniProtKB:Q8IZP0\|UniProtKB:Q9P206\|UniProtKB:Q9UKE5	150520179	PMID:33961781	IntAct	PMID:33961781
NCK1	Human	protein binding	enables	IPI	UniProtKB:P00533\|UniProtKB:Q15208	150520179	PMID:31980649	IntAct	PMID:31980649
NCK1	Human	protein binding	enables	IPI	UniProtKB:Q05193\|UniProtKB:Q07889	150520179	PMID:10206341	IntAct	PMID:10206341
NCK1	Human	protein domain specific binding	enables	IEA	UniProtKB:Q99M51\|ensembl:ENSMUSP00000112221	150520179		Ensembl	GO_REF:0000107
NCK1	Human	protein kinase inhibitor activity	enables	IDA		150520179	PMID:18835251	UniProt	PMID:18835251
NCK1	Human	protein sequestering activity	enables	IDA		150520179	PMID:38614099	UniProt	PMID:38614099
NCK1	Human	protein-macromolecule adaptor activity	enables	IDA		150520179	PMID:21707536	FlyBase	PMID:21707536
NCK1	Human	receptor tyrosine kinase binding	enables	IPI	UniProtKB:P29317	150520179	PMID:23358419	UniProt	PMID:23358419
NCK1	Human	receptor tyrosine kinase binding	enables	IBA	FB:FBgn0024811\|PANTHER:PTN001072514\|UniProtKB:P16333	150520179		GO_Central	GO_REF:0000033
NCK1	Human	signaling adaptor activity	enables	IDA		150520179	PMID:16835242	ParkinsonsUK-UCL	PMID:16835242
NCK1	Human	signaling adaptor activity	enables	IBA	MGI:104686\|MGI:88508\|PANTHER:PTN001072514\|UniProtKB:P16333\|UniProtKB:P46108	150520179		GO_Central	GO_REF:0000033
NCK1	Human	signaling receptor binding	enables	IPI	UniProtKB:P07766	150520179	PMID:12110186	UniProt	PMID:12110186
NCK1	Human	signaling receptor complex adaptor activity	enables	NAS		150520179	PMID:12110186	UniProt	PMID:12110186

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NCK1	Human	vascular endothelial growth factor signaling pathway		TAS		2298729		RGD

Imported Annotations - KEGG (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NCK1	Human	epidermal growth factor/neuregulin signaling pathway		IEA		6907045		KEGG	hsa:04012
NCK1	Human	pathogenic Escherichia coli infection pathway		IEA		6907045		KEGG	hsa:05130
NCK1	Human	T cell receptor signaling pathway		IEA		6907045		KEGG	hsa:04660

Imported Annotations - PID (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
NCK1	Human	E-cadherin signaling pathway		EXP		6484113		PID	PID:200182
NCK1	Human	ephrin - ephrin receptor bidirectional signaling axis		EXP		6484113		PID	PID:200052
NCK1	Human	epidermal growth factor/neuregulin signaling pathway		EXP		6484113		PID	PID:200101
NCK1	Human	insulin signaling pathway		EXP		6484113		PID	PID:200014
NCK1	Human	platelet-derived growth factor signaling pathway		EXP		6484113		PID	PID:200149
NCK1	Human	vascular endothelial growth factor signaling pathway		EXP		6484113		PID	PID:200188

#	Reference Title	Reference Citation
1.	GOAs Human GO annotations	GOA_HUMAN data from the GO Consortium
2.	Vascular endothelial growth factor receptor-2: structure, function, intracellular signalling and therapeutic inhibition.	Holmes K, etal., Cell Signal. 2007 Oct;19(10):2003-12. Epub 2007 Jun 12.
3.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
4.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:1333046	PMID:1333047	PMID:1448108	PMID:2107526	PMID:7517397	PMID:7565724	PMID:7706279	PMID:7806213	PMID:7862111	PMID:7926767	PMID:7956370	PMID:8561895
PMID:8605018	PMID:8662998	PMID:8810325	PMID:8824201	PMID:8879209	PMID:8890167	PMID:8910519	PMID:9006905	PMID:9010224	PMID:9024622	PMID:9135144	PMID:9233798
PMID:9314836	PMID:9344857	PMID:9346925	PMID:9362449	PMID:9405464	PMID:9430661	PMID:9600074	PMID:9694849	PMID:9697839	PMID:9737977	PMID:9837978	PMID:9843378
PMID:9846482	PMID:9851874	PMID:9891069	PMID:10022833	PMID:10026169	PMID:10202139	PMID:10204582	PMID:10206341	PMID:10229072	PMID:10330411	PMID:10372803	PMID:10391903
PMID:10409713	PMID:10428862	PMID:10508618	PMID:10521462	PMID:10671570	PMID:10747096	PMID:10747847	PMID:10766742	PMID:10805734	PMID:10808124	PMID:10829062	PMID:10967110
PMID:11024037	PMID:11157752	PMID:11160719	PMID:11240126	PMID:11278241	PMID:11278436	PMID:11278500	PMID:11278553	PMID:11279207	PMID:11340081	PMID:11418237	PMID:11418612
PMID:11483358	PMID:11487585	PMID:11494134	PMID:11533668	PMID:11551902	PMID:11557983	PMID:11689432	PMID:11724572	PMID:11741599	PMID:11950595	PMID:11959995	PMID:12007418
PMID:12074588	PMID:12087092	PMID:12091389	PMID:12110186	PMID:12135674	PMID:12149262	PMID:12154000	PMID:12181570	PMID:12214271	PMID:12379115	PMID:12477932	PMID:12620186
PMID:12819203	PMID:14517291	PMID:14559906	PMID:14676213	PMID:14702039	PMID:14757753	PMID:15051508	PMID:15144186	PMID:15187089	PMID:15297625	PMID:15342556	PMID:15388330
PMID:15469942	PMID:15489334	PMID:15556869	PMID:15558067	PMID:15696170	PMID:15908432	PMID:15929943	PMID:15951569	PMID:16137687	PMID:16273093	PMID:16344560	PMID:16374509
PMID:16503409	PMID:16525419	PMID:16543952	PMID:16595635	PMID:16636066	PMID:16636290	PMID:16729043	PMID:16777958	PMID:16835242	PMID:16966330	PMID:17474147	PMID:17617578
PMID:17803907	PMID:17868192	PMID:17906149	PMID:17944934	PMID:17984209	PMID:18067320	PMID:18212058	PMID:18296648	PMID:18320063	PMID:18835251	PMID:18955169	PMID:19242519
PMID:19523119	PMID:19807924	PMID:20079431	PMID:20129698	PMID:20237496	PMID:20562827	PMID:20800603	PMID:20850195	PMID:21309750	PMID:21397687	PMID:21536650	PMID:21664272
PMID:21707536	PMID:21719533	PMID:21725281	PMID:21873635	PMID:21880263	PMID:21900206	PMID:21988832	PMID:22074159	PMID:22132889	PMID:22267732	PMID:22323535	PMID:22327338
PMID:22534133	PMID:22613834	PMID:22677168	PMID:22745667	PMID:22844345	PMID:22964333	PMID:22973453	PMID:22974441	PMID:23358419	PMID:23426619	PMID:23444376	PMID:23448571
PMID:23706161	PMID:24086708	PMID:24284073	PMID:24287595	PMID:24470497	PMID:24658140	PMID:24728074	PMID:24769494	PMID:25056061	PMID:25137142	PMID:25218436	PMID:25241761
PMID:25321392	PMID:25359136	PMID:25398386	PMID:25402006	PMID:25468996	PMID:25482634	PMID:25714462	PMID:25814554	PMID:26157164	PMID:26163016	PMID:26186194	PMID:26344197
PMID:26496610	PMID:26553976	PMID:26554011	PMID:26590318	PMID:26638075	PMID:26760575	PMID:26871637	PMID:27033705	PMID:27432908	PMID:28455143	PMID:28455144	PMID:28514442
PMID:28675297	PMID:28954862	PMID:29089450	PMID:29568061	PMID:29911835	PMID:29991678	PMID:30146921	PMID:30442385	PMID:31452512	PMID:31467278	PMID:31638742	PMID:31674657
PMID:31761329	PMID:31769754	PMID:31871319	PMID:31980649	PMID:32203420	PMID:32296183	PMID:32393512	PMID:32427580	PMID:32446368	PMID:32468886	PMID:32640226	PMID:32739212
PMID:33629937	PMID:33637726	PMID:33917227	PMID:33961781	PMID:33974352	PMID:34273398	PMID:34597346	PMID:34672954	PMID:34709727	PMID:34846647	PMID:35218517	PMID:35271311
PMID:35384245	PMID:35902806	PMID:35914814	PMID:36811957	PMID:36963288	PMID:37232246	PMID:37478010	PMID:37694355	PMID:37774976	PMID:38280479	PMID:38614099	PMID:39009827
PMID:39231216

NCK1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	136,862,208 - 136,951,606 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	136,862,208 - 136,951,606 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	136,581,050 - 136,670,448 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	138,063,763 - 138,150,658 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	138,063,770 - 138,150,665	NCBI
Celera	3	135,007,352 - 135,094,246 (+)	NCBI		Celera
Cytogenetic Map	3	q22.3	NCBI
HuRef	3	133,957,144 - 134,043,755 (+)	NCBI		HuRef
CHM1_1	3	136,544,712 - 136,631,607 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	139,602,861 - 139,692,274 (+)	NCBI		T2T-CHM13v2.0

Nck1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	100,376,047 - 100,428,187 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	100,374,346 - 100,428,187 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	100,494,302 - 100,546,134 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	100,492,293 - 100,546,134 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	100,395,422 - 100,446,472 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	100,304,355 - 100,355,405 (-)	NCBI		MGSCv36	mm8
Celera	9	100,033,773 - 100,084,727 (-)	NCBI		Celera
Cytogenetic Map	9	E3.3	NCBI
cM Map	9	52.69	NCBI

Nck1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	109,897,723 - 109,958,247 (-)	NCBI		GRCr8
mRatBN7.2	8	101,018,610 - 101,079,237 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	101,018,702 - 101,079,300 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	106,689,323 - 106,743,736 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	104,888,640 - 104,943,070 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	102,731,183 - 102,785,617 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	108,787,797 - 108,847,779 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	108,787,798 - 108,847,779 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	108,204,372 - 108,264,127 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	105,346,933 - 105,409,843 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	105,365,785 - 105,380,767 (-)	NCBI
Celera	8	100,416,045 - 100,476,576 (-)	NCBI		Celera
Cytogenetic Map	8	q31	NCBI

Nck1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955501	1,867,956 - 1,963,091 (-)	NCBI	ChiLan1.0	ChiLan1.0

NCK1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	134,779,250 - 134,866,238 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	134,783,966 - 134,872,031 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	133,902,463 - 133,990,414 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	141,362,407 - 141,451,444 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	141,427,870 - 141,451,444 (+)	Ensembl	panpan1.1		panPan2

NCK1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	33,297,660 - 33,374,025 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	33,297,756 - 33,372,534 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	33,281,832 - 33,358,413 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	33,827,357 - 33,903,748 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	33,827,416 - 33,905,987 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	33,509,571 - 33,586,142 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	33,575,236 - 33,651,579 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	33,819,866 - 33,896,593 (+)	NCBI		UU_Cfam_GSD_1.0

Nck1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	72,886,653 - 72,961,283 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936529	9,701,530 - 9,721,869 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936529	9,647,161 - 9,718,512 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NCK1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	77,863,701 - 77,945,468 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	77,863,655 - 77,940,944 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	85,560,199 - 85,580,490 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NCK1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	53,501,152 - 53,595,500 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	53,500,623 - 53,523,576 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	26,543,119 - 26,636,848 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nck1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	13,226,315 - 13,366,661 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624730	13,271,575 - 13,366,930 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in NCK1
31 total Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 3q22.1-23(chr3:132690641-141064444)x1	copy number loss	Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051570]\|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051570]\|See cases [RCV000051570]	Chr3:132690641..141064444 [GRCh38] Chr3:132409485..140783286 [GRCh37] Chr3:133892175..142265976 [NCBI36] Chr3:3q22.1-23	pathogenic
GRCh38/hg38 3q22.1-22.3(chr3:132972567-136894498)x1	copy number loss	See cases [RCV000051571]	Chr3:132972567..136894498 [GRCh38] Chr3:132691411..136613340 [GRCh37] Chr3:134174101..138096030 [NCBI36] Chr3:3q22.1-22.3	pathogenic
GRCh38/hg38 3q22.2-24(chr3:135227451-145870770)x1	copy number loss	See cases [RCV000051572]	Chr3:135227451..145870770 [GRCh38] Chr3:134946293..145588557 [GRCh37] Chr3:136428983..147071247 [NCBI36] Chr3:3q22.2-24	pathogenic
GRCh38/hg38 3q13.11-29(chr3:103426882-198110178)x3	copy number gain	See cases [RCV000134948]	Chr3:103426882..198110178 [GRCh38] Chr3:103145726..197837049 [GRCh37] Chr3:104628416..199321446 [NCBI36] Chr3:3q13.11-29	pathogenic
GRCh38/hg38 3q22.1-24(chr3:129817243-143381624)x1	copy number loss	See cases [RCV000136558]	Chr3:129817243..143381624 [GRCh38] Chr3:129536086..143100466 [GRCh37] Chr3:131018776..144583156 [NCBI36] Chr3:3q22.1-24	pathogenic
GRCh38/hg38 3q22.2-25.1(chr3:134257180-149729538)x1	copy number loss	See cases [RCV000138135]	Chr3:134257180..149729538 [GRCh38] Chr3:133976022..149447325 [GRCh37] Chr3:135458712..150930015 [NCBI36] Chr3:3q22.2-25.1	pathogenic\|likely benign
GRCh38/hg38 3q22.1-23(chr3:130401265-139005019)x1	copy number loss	See cases [RCV000139240]	Chr3:130401265..139005019 [GRCh38] Chr3:130120109..138723861 [GRCh37] Chr3:131602799..140206551 [NCBI36] Chr3:3q22.1-23	pathogenic
GRCh38/hg38 3q22.2-23(chr3:134333553-141701458)x1	copy number loss	See cases [RCV000140453]	Chr3:134333553..141701458 [GRCh38] Chr3:134052395..141420300 [GRCh37] Chr3:135535085..142902990 [NCBI36] Chr3:3q22.2-23	pathogenic
GRCh38/hg38 3q22.1-23(chr3:129817243-141425155)x1	copy number loss	See cases [RCV000140995]	Chr3:129817243..141425155 [GRCh38] Chr3:129536086..141143997 [GRCh37] Chr3:131018776..142626687 [NCBI36] Chr3:3q22.1-23	pathogenic
GRCh38/hg38 3q21.3-23(chr3:126106779-140918089)x3	copy number gain	See cases [RCV000142010]	Chr3:126106779..140918089 [GRCh38] Chr3:125825622..140636931 [GRCh37] Chr3:127308312..142119621 [NCBI36] Chr3:3q21.3-23	uncertain significance
GRCh38/hg38 3q11.1-24(chr3:93800620-145695381)x3	copy number gain	See cases [RCV000142340]	Chr3:93800620..145695381 [GRCh38] Chr3:93519464..145413168 [GRCh37] Chr3:95002154..146895858 [NCBI36] Chr3:3q11.1-24	pathogenic
GRCh38/hg38 3q22.1-24(chr3:132716978-144784743)x1	copy number loss	See cases [RCV000143634]	Chr3:132716978..144784743 [GRCh38] Chr3:132435822..144503585 [GRCh37] Chr3:133918512..145986275 [NCBI36] Chr3:3q22.1-24	pathogenic
GRCh37/hg19 3q22.3-23(chr3:135935129-141867748)x3	copy number gain	See cases [RCV000239877]	Chr3:135935129..141867748 [GRCh37] Chr3:3q22.3-23	likely pathogenic
NM_001291999.2(NCK1):c.1061A>G (p.Glu354Gly)	single nucleotide variant	not specified [RCV004315422]	Chr3:136948380 [GRCh38] Chr3:136667222 [GRCh37] Chr3:3q22.3	uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3	copy number gain	See cases [RCV000511055]	Chr3:61892..197851986 [GRCh37] Chr3:3p26.3-q29	pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)	copy number gain	See cases [RCV000512358]	Chr3:61892..197851986 [GRCh37] Chr3:3p26.3-q29	pathogenic
GRCh37/hg19 3q22.3(chr3:135805001-137555312)x3	copy number gain	not provided [RCV000682306]	Chr3:135805001..137555312 [GRCh37] Chr3:3q22.3	uncertain significance
GRCh38/hg38 3q22.2-22.3(chr3:135423479-136961152)x1	copy number loss	Intellectual disability, autosomal dominant 47 [RCV000680252]	Chr3:135423479..136961152 [GRCh38] Chr3:135142319..136679992 [GRCh37] Chr3:3q22.2-22.3	likely pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3	copy number gain	not provided [RCV000742138]	Chr3:61495..197838262 [GRCh37] Chr3:3p26.3-q29	pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3	copy number gain	not provided [RCV000742133]	Chr3:60174..197948027 [GRCh37] Chr3:3p26.3-q29	pathogenic
GRCh37/hg19 3q22.2-24(chr3:135288025-146874012)	copy number gain	not provided [RCV000767703]	Chr3:135288025..146874012 [GRCh37] Chr3:3q22.2-24	pathogenic
GRCh37/hg19 3q22.2-23(chr3:135186881-140826836)x3	copy number gain	not provided [RCV000846949]	Chr3:135186881..140826836 [GRCh37] Chr3:3q22.2-23	uncertain significance
Single allele	deletion	Deafness-lymphedema-leukemia syndrome [RCV001541925]	Chr3:127966423..136853218 [GRCh37] Chr3:3q21.3-22.3	pathogenic
NM_001291999.2(NCK1):c.772G>C (p.Gly258Arg)	single nucleotide variant	not provided [RCV000956139]	Chr3:136946128 [GRCh38] Chr3:136664970 [GRCh37] Chr3:3q22.3	benign
GRCh37/hg19 3q13.31-26.31(chr3:116620308-172042292)x3	copy number gain	not provided [RCV002472621]	Chr3:116620308..172042292 [GRCh37] Chr3:3q13.31-26.31	pathogenic
NM_001291999.2(NCK1):c.955G>A (p.Val319Ile)	single nucleotide variant	not specified [RCV004221683]	Chr3:136948274 [GRCh38] Chr3:136667116 [GRCh37] Chr3:3q22.3	uncertain significance
NM_001291999.2(NCK1):c.433C>T (p.Arg145Cys)	single nucleotide variant	not specified [RCV004228764]	Chr3:136945789 [GRCh38] Chr3:136664631 [GRCh37] Chr3:3q22.3	uncertain significance
NM_001291999.2(NCK1):c.1045A>T (p.Met349Leu)	single nucleotide variant	not specified [RCV004183031]	Chr3:136948364 [GRCh38] Chr3:136667206 [GRCh37] Chr3:3q22.3	uncertain significance
NM_001291999.2(NCK1):c.188G>A (p.Arg63Gln)	single nucleotide variant	not specified [RCV004176338]	Chr3:136928189 [GRCh38] Chr3:136647031 [GRCh37] Chr3:3q22.3	uncertain significance
NM_001291999.2(NCK1):c.817C>T (p.Leu273Phe)	single nucleotide variant	not specified [RCV004171690]	Chr3:136946173 [GRCh38] Chr3:136665015 [GRCh37] Chr3:3q22.3	uncertain significance
NM_001291999.2(NCK1):c.496A>G (p.Ser166Gly)	single nucleotide variant	not specified [RCV004133707]	Chr3:136945852 [GRCh38] Chr3:136664694 [GRCh37] Chr3:3q22.3	uncertain significance
NM_001291999.2(NCK1):c.391A>G (p.Thr131Ala)	single nucleotide variant	not specified [RCV004258615]	Chr3:136945747 [GRCh38] Chr3:136664589 [GRCh37] Chr3:3q22.3	uncertain significance
NM_001291999.2(NCK1):c.512A>G (p.His171Arg)	single nucleotide variant	not specified [RCV004269259]	Chr3:136945868 [GRCh38] Chr3:136664710 [GRCh37] Chr3:3q22.3	uncertain significance
NM_001291999.2(NCK1):c.554A>C (p.Asn185Thr)	single nucleotide variant	not specified [RCV004473656]	Chr3:136945910 [GRCh38] Chr3:136664752 [GRCh37] Chr3:3q22.3	uncertain significance
NM_001291999.2(NCK1):c.973G>A (p.Gly325Arg)	single nucleotide variant	not specified [RCV004473664]	Chr3:136948292 [GRCh38] Chr3:136667134 [GRCh37] Chr3:3q22.3	uncertain significance
NM_001291999.2(NCK1):c.999A>T (p.Gln333His)	single nucleotide variant	not specified [RCV004473669]	Chr3:136948318 [GRCh38] Chr3:136667160 [GRCh37] Chr3:3q22.3	uncertain significance
NM_001291999.2(NCK1):c.179A>G (p.Asn60Ser)	single nucleotide variant	not specified [RCV004473640]	Chr3:136928180 [GRCh38] Chr3:136647022 [GRCh37] Chr3:3q22.3	uncertain significance
NM_001291999.2(NCK1):c.620A>C (p.Glu207Ala)	single nucleotide variant	not specified [RCV004652500]	Chr3:136945976 [GRCh38] Chr3:136664818 [GRCh37] Chr3:3q22.3	uncertain significance
NM_001291999.2(NCK1):c.98A>G (p.Asp33Gly)	single nucleotide variant	not specified [RCV004641302]	Chr3:136928099 [GRCh38] Chr3:136646941 [GRCh37] Chr3:3q22.3	uncertain significance
NM_001291999.2(NCK1):c.609A>T (p.Ser203=)	single nucleotide variant	not provided [RCV004722396]	Chr3:136945965 [GRCh38] Chr3:136664807 [GRCh37] Chr3:3q22.3	likely benign
NM_001291999.2(NCK1):c.446A>G (p.Asn149Ser)	single nucleotide variant	not specified [RCV004826594]	Chr3:136945802 [GRCh38] Chr3:136664644 [GRCh37] Chr3:3q22.3	uncertain significance
NM_001291999.2(NCK1):c.999A>C (p.Gln333His)	single nucleotide variant	not specified [RCV004826595]	Chr3:136948318 [GRCh38] Chr3:136667160 [GRCh37] Chr3:3q22.3	uncertain significance

Predicted Target Of

	Summary Value
Count of predictions:	1991
Count of miRNA genes:	841
Interacting mature miRNAs:	972
Transcripts:	ENST00000288986, ENST00000460960, ENST00000467911, ENST00000469404, ENST00000476286, ENST00000478862, ENST00000481752, ENST00000482071, ENST00000485096, ENST00000488930, ENST00000491539, ENST00000496489
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
597288856	GWAS1384930_H	body mass index QTL GWAS1384930 (human)		0.000001	body mass index	body mass index (BMI) (CMO:0000105)	3	136900067	136900068	Human
597244698	GWAS1340772_H	high density lipoprotein cholesterol measurement QTL GWAS1340772 (human)		1e-10	high density lipoprotein cholesterol measurement	blood high density lipoprotein cholesterol level (CMO:0000052)	3	136862769	136862770	Human
407220038	GWAS869014_H	lymphocyte count QTL GWAS869014 (human)		1e-26	lymphocyte count	blood lymphocyte count (CMO:0000031)	3	136903718	136903719	Human
597350233	GWAS1446307_H	myocardial infarction QTL GWAS1446307 (human)		1e-09	myocardial infarction		3	136913695	136913696	Human
597241565	GWAS1337639_H	triglyceride measurement QTL GWAS1337639 (human)		3e-13	triglyceride measurement	blood triglyceride level (CMO:0000118)	3	136862769	136862770	Human
597082002	GWAS1178076_H	neutrophil count QTL GWAS1178076 (human)		3e-10	neutrophil quantity (VT:0000222)	blood neutrophil count (CMO:0000030)	3	136870051	136870052	Human
597088273	GWAS1184347_H	monocyte count QTL GWAS1184347 (human)		1e-13	monocyte quantity (VT:0000223)	blood monocyte count (CMO:0000032)	3	136867921	136867922	Human
597240275	GWAS1336349_H	IGF-1 measurement QTL GWAS1336349 (human)		1e-15	IGF-1 measurement	blood apoliprotein B level (CMO:0000522)	3	136862769	136862770	Human
597580821	GWAS1637681_H	lymphocyte count QTL GWAS1637681 (human)		2e-12	lymphocyte count	blood lymphocyte count (CMO:0000031)	3	136881825	136881826	Human
597224022	GWAS1320096_H	aspartate aminotransferase to alanine aminotransferase ratio QTL GWAS1320096 (human)		5e-20	aspartate aminotransferase to alanine aminotransferase ratio	serum aspartate aminotransferase activity level to alanine aminotransferase activity level ratio (CMO:0002245)	3	136862769	136862770	Human
597292887	GWAS1388961_H	lymphocyte measurement, neutrophil measurement QTL GWAS1388961 (human)		3e-08	lymphocyte measurement, neutrophil measurement		3	136917843	136917844	Human
406888079	GWAS537055_H	Hodgkins lymphoma, multiple myeloma, chronic lymphocytic leukemia QTL GWAS537055 (human)		2e-09	leukocyte integrity trait (VT:0010898)		3	136870707	136870708	Human
597177930	GWAS1274004_H	phospholipids in small VLDL measurement QTL GWAS1274004 (human)		1e-10	phospholipids in small VLDL measurement	blood very low density lipoprotein phospholipid level (CMO:0001571)	3	136902346	136902347	Human
597224907	GWAS1320981_H	total cholesterol measurement QTL GWAS1320981 (human)		1e-09	total cholesterol measurement	blood total cholesterol level (CMO:0000051)	3	136862769	136862770	Human
597028291	GWAS1124365_H	blood urea nitrogen measurement QTL GWAS1124365 (human)		5e-16	blood urea nitrogen measurement	blood urea nitrogen level (CMO:0000049)	3	136920133	136920134	Human
597580094	GWAS1636954_H	lymphocyte count QTL GWAS1636954 (human)		3e-14	lymphocyte count	blood lymphocyte count (CMO:0000031)	3	136933122	136933123	Human
597224377	GWAS1320451_H	bilirubin measurement QTL GWAS1320451 (human)		5e-26	bilirubin measurement	serum total bilirubin level (CMO:0000376)	3	136862769	136862770	Human
597223993	GWAS1320067_H	serum gamma-glutamyl transferase measurement QTL GWAS1320067 (human)		3e-11	serum gamma-glutamyl transferase measurement	serum gamma-glutamyltransferase activity level (CMO:0002241)	3	136862769	136862770	Human
597185978	GWAS1282052_H	total lipids in medium VLDL QTL GWAS1282052 (human)		4e-10	total lipids in medium VLDL		3	136868275	136868276	Human
596955830	GWAS1075349_H	lymphocyte measurement, neutrophil measurement QTL GWAS1075349 (human)		3e-08	lymphocyte measurement, neutrophil measurement		3	136917843	136917844	Human
597078899	GWAS1174973_H	platelet count QTL GWAS1174973 (human)		1e-22	platelet quantity (VT:0003179)	platelet count (CMO:0000029)	3	136906594	136906595	Human
597082672	GWAS1178746_H	monocyte count QTL GWAS1178746 (human)		2e-16	monocyte quantity (VT:0000223)	blood monocyte count (CMO:0000032)	3	136863111	136863112	Human
597074672	GWAS1170746_H	neuroticism measurement QTL GWAS1170746 (human)		3e-11	neuroticism measurement		3	136896426	136896427	Human
597246577	GWAS1342651_H	bilirubin measurement QTL GWAS1342651 (human)		2e-41	bilirubin measurement	serum total bilirubin level (CMO:0000376)	3	136862769	136862770	Human
1300026	BP36_H	Blood pressure QTL 36 (human)	4.04		Blood pressure	hypertension susceptibility	3	135720453	161720453	Human
597071740	GWAS1167814_H	neuroticism measurement QTL GWAS1167814 (human)		4e-08	neuroticism measurement		3	136896426	136896427	Human
597105018	GWAS1201092_H	platelet component distribution width QTL GWAS1201092 (human)		2e-10	platelet size trait (VT:0010457)	platelet distribution width (CMO:0001350)	3	136945895	136945896	Human
597243895	GWAS1339969_H	sex hormone-binding globulin measurement QTL GWAS1339969 (human)		3e-52	sex hormone-binding globulin measurement		3	136862769	136862770	Human
597114361	GWAS1210435_H	platelet count QTL GWAS1210435 (human)		2e-16	platelet quantity (VT:0003179)	platelet count (CMO:0000029)	3	136906594	136906595	Human
597257128	GWAS1353202_H	blood protein measurement QTL GWAS1353202 (human)		3e-09	blood protein amount (VT:0005416)	blood protein measurement (CMO:0000028)	3	136862769	136862770	Human
596975396	GWAS1094915_H	body height QTL GWAS1094915 (human)		9e-21	body height		3	136864497	136864498	Human
597344491	GWAS1440565_H	body mass index QTL GWAS1440565 (human)		4e-14	body mass index	body mass index (BMI) (CMO:0000105)	3	136890996	136890997	Human
597254314	GWAS1350388_H	apolipoprotein A 1 measurement QTL GWAS1350388 (human)		3e-14	apolipoprotein A 1 measurement	blood apolipoprotein AI level (CMO:0000520)	3	136862769	136862770	Human
597099169	GWAS1195243_H	monocyte count QTL GWAS1195243 (human)		5e-18	monocyte quantity (VT:0000223)	blood monocyte count (CMO:0000032)	3	136891788	136891789	Human
597615144	GWAS1672004_H	platelet count QTL GWAS1672004 (human)		7e-14	platelet quantity (VT:0003179)	platelet count (CMO:0000029)	3	136896426	136896427	Human
597048161	GWAS1144235_H	BMI-adjusted waist-hip ratio QTL GWAS1144235 (human)		1e-08	body size trait (VT:0100005)		3	136878278	136878279	Human
597086510	GWAS1182584_H	platelet count QTL GWAS1182584 (human)		6e-21	platelet quantity (VT:0003179)	platelet count (CMO:0000029)	3	136912433	136912434	Human
1298415	BP24_H	Blood pressure QTL 24 (human)	2.9		Blood pressure	hypertension susceptibility	3	135720453	161720453	Human
597247141	GWAS1343215_H	serum alanine aminotransferase measurement QTL GWAS1343215 (human)		9e-17	serum alanine aminotransferase measurement	serum alanine aminotransferase activity level (CMO:0000575)	3	136862769	136862770	Human
597087659	GWAS1183733_H	body mass index QTL GWAS1183733 (human)		2e-10	body mass index	body mass index (BMI) (CMO:0000105)	3	136881825	136881826	Human
597246503	GWAS1342577_H	alkaline phosphatase measurement QTL GWAS1342577 (human)		2e-18	alkaline phosphatase measurement	blood alkaline phosphatase activity level (CMO:0000576)	3	136862769	136862770	Human
597246759	GWAS1342833_H	low density lipoprotein cholesterol measurement QTL GWAS1342833 (human)		5e-13	low density lipoprotein cholesterol measurement	blood low density lipoprotein cholesterol level (CMO:0000053)	3	136862769	136862770	Human
597347557	GWAS1443631_H	body mass index QTL GWAS1443631 (human)		2e-10	body mass index	body mass index (BMI) (CMO:0000105)	3	136902496	136902497	Human

D3S3617

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	3	136,601,263 - 136,601,454	UniSTS	GRCh37
Build 36	3	138,083,953 - 138,084,144	RGD	NCBI36
Celera	3	135,027,549 - 135,027,740	RGD
Cytogenetic Map	3	q21	UniSTS
HuRef	3	133,977,036 - 133,977,227	UniSTS
Marshfield Genetic Map	3	149.97	RGD
Marshfield Genetic Map	3	149.97	UniSTS
Genethon Genetic Map	3	151.5	UniSTS
deCODE Assembly Map	3	144.06	UniSTS
Whitehead-YAC Contig Map	3		UniSTS

D3S3349

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	3	136,667,299 - 136,667,393	UniSTS	GRCh37
Build 36	3	138,149,989 - 138,150,083	RGD	NCBI36
Celera	3	135,093,577 - 135,093,671	RGD
Cytogenetic Map	3	q21	UniSTS
HuRef	3	134,043,086 - 134,043,180	UniSTS
GeneMap99-GB4 RH Map	3	491.07	UniSTS
Whitehead-RH Map	3	632.5	UniSTS
Whitehead-YAC Contig Map	3		UniSTS
NCBI RH Map	3	1200.8	UniSTS

SHGC-77376

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	3	136,667,113 - 136,667,324	UniSTS	GRCh37
Build 36	3	138,149,803 - 138,150,014	RGD	NCBI36
Celera	3	135,093,391 - 135,093,602	RGD
Cytogenetic Map	3	q21	UniSTS
HuRef	3	134,042,900 - 134,043,111	UniSTS
TNG Radiation Hybrid Map	3	78400.0	UniSTS
GeneMap99-GB4 RH Map	3	486.24	UniSTS
NCBI RH Map	3	1200.8	UniSTS

D3S4077

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	3	136,579,575 - 136,579,700	UniSTS	GRCh37
Build 36	3	138,062,265 - 138,062,390	RGD	NCBI36
Celera	3	135,005,877 - 135,006,002	RGD
Cytogenetic Map	3	q21	UniSTS
HuRef	3	133,955,669 - 133,955,794	UniSTS
Whitehead-RH Map	3	624.9	UniSTS
NCBI RH Map	3	1200.8	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	entire extraembryonic component	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	pharyngeal arch	renal system	reproductive system	respiratory system	sensory system	visual system
1204	2439	2788	2253	4974	1726	2351	6	624	1951	465	2270	7306	6472	53	3734	1	852	1744	1617	175	1


RefSeq Transcripts	NM_001190796	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001291999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_006153	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_024453538	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_047448189	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_047448190	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_047448191	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054346631	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054346632	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054346633	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054346634	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC011597	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK095534	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK301460	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK312692	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC006403	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BP339594	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471052	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068275	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DA265476	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DA855124	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DB117533	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KU178218	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KU178219	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KU178220	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X17576	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENST00000288986 ⟹ ENSP00000288986

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	136,862,208 - 136,949,126 (+)	Ensembl

Ensembl Acc Id:

ENST00000460960

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	136,862,267 - 136,928,473 (+)	Ensembl

Ensembl Acc Id:

ENST00000467911 ⟹ ENSP00000418060

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	136,930,502 - 136,948,432 (+)	Ensembl

Ensembl Acc Id:

ENST00000469404 ⟹ ENSP00000419631

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	136,930,470 - 136,949,823 (+)	Ensembl

Ensembl Acc Id:

ENST00000476286 ⟹ ENSP00000418513

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	136,862,264 - 136,928,227 (+)	Ensembl

Ensembl Acc Id:

ENST00000478862

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	136,862,267 - 136,928,724 (+)	Ensembl

Ensembl Acc Id:

ENST00000481752 ⟹ ENSP00000417273

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	136,862,208 - 136,951,606 (+)	Ensembl

Ensembl Acc Id:

ENST00000482071

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	136,945,725 - 136,947,047 (+)	Ensembl

Ensembl Acc Id:

ENST00000485096 ⟹ ENSP00000419677

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	136,862,242 - 136,945,702 (+)	Ensembl

Ensembl Acc Id:

ENST00000488930 ⟹ ENSP00000417729

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	136,862,298 - 136,946,218 (+)	Ensembl

Ensembl Acc Id:

ENST00000491539 ⟹ ENSP00000419302

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	136,862,233 - 136,945,743 (+)	Ensembl

Ensembl Acc Id:

ENST00000496489 ⟹ ENSP00000419544

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	136,928,039 - 136,946,214 (+)	Ensembl

RefSeq Acc Id:

NM_001190796 ⟹ NP_001177725

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	3	136,930,502 - 136,951,606 (+)	NCBI
GRCh37	3	136,581,050 - 136,670,446 (+)	NCBI
HuRef	3	133,957,144 - 134,043,755 (+)	ENTREZGENE
CHM1_1	3	136,612,954 - 136,634,091 (+)	NCBI
T2T-CHM13v2.0	3	139,671,204 - 139,692,274 (+)	NCBI

Sequence:

show sequence

ACTGAGAATTATCCTGAGCTGTGTTAACAAACTGACAGAACACAGAATTTTTACTCAAAATGGATTGGTTAAACGTCTTTAAAGATTTTTTCAGCATTGGAAAAGTGAAAAGAAAACCTAGTGTGCCA
GATTCTGCATCTCCTGCTGATGATAGTTTTGTTGACCCAGGGGAACGTCTCTATGACCTCAACATGCCCGCTTATGTGAAATTTAACTACATGGCTGAGAGAGAGGATGAATTATCATTGATAAAGGG
GACAAAGGTGATCGTCATGGAGAAATGCAGTGATGGGTGGTGGCGTGGTAGCTACAATGGACAAGTTGGATGGTTCCCTTCAAACTATGTAACTGAAGAAGGTGACAGTCCTTTGGGTGACCATGTGG
GTTCTCTGTCAGAGAAATTAGCAGCAGTCGTCAATAACCTAAATACTGGGCAAGTGTTGCATGTGGTACAGGCTCTTTACCCATTCAGCTCATCTAATGATGAAGAACTTAATTTCGAGAAAGGAGAT
GTAATGGATGTTATTGAAAAACCTGAAAATGACCCAGAGTGGTGGAAATGCAGGAAGATCAATGGTATGGTTGGTCTAGTACCAAAAAACTATGTTACCGTTATGCAGAATAATCCATTAACTTCAGG
TTTGGAACCATCACCTCCACAGTGTGATTACATTAGGCCTTCACTCACTGGAAAGTTTGCTGGCAATCCTTGGTATTATGGCAAAGTCACCAGGCATCAAGCAGAAATGGCATTAAATGAAAGAGGAC
ATGAAGGGGATTTCCTCATTCGTGATAGTGAATCTTCGCCAAATGATTTCTCAGTATCACTAAAAGCACAAGGGAAAAACAAGCATTTTAAAGTCCAACTAAAAGAGACTGTCTACTGCATTGGGCAG
CGTAAATTCAGCACCATGGAAGAACTTGTAGAACATTACAAAAAGGCACCAATTTTTACAAGTGAACAAGGAGAAAAATTATATCTTGTCAAGCATTTATCATGATACTGCTGACCAGAAGTGACTGC
TGTGTAGCTGTAATTTGTCATGTAATTGAAGACTGAGAAAATGTTGGGTCCAGTCGTGCTTGATTGGAAATTGTTGTTTCTAAATCTATATGAGAATTGACAATAAGTATTTTTATTATAACTCAGCC
CATACATATATACTATGTATGCAGTGCATCTGCATAGAACAGTTCCTTATCCTTGGCCTTCTGTTTTATTGTTTTTTTCTTTGCTGTTTTCCCTTTGCTTCTAATATTACAGTTTTGTATTTTGTAAA
CAAAAATCAAATAATGCATATCAGAATCTTTATATGGAAGAAATCCTTTATTGCCTTTCCTTTGTTTCCTTGTAAAGGCACCCTGTTCTGTTATGGTTTTTCATTATATAAAATTATTATATCTATAT
ATGACATATGCTAAAATTTCTTGGAGAGTGTTAATCTTTTCTGTGACTAAATAGCAATAATAAGTGGAAAATTAGAAATTATTTCCAGGTATTATATTTGTCACAGGCCATTGTAAATACCAAGTATA
TTGTGTCTGCCATAATTTTTAAAAATACATTCATTGTCTTCAGTCATACAGCAAGACACATGAGACATAGATTAGAAAACATGTTGTACAATTTTAATTTACAACTGTTGGAAATAAAAATCACTTAA
TTTTTTTCCAGTGCTTCTCCCTCATCTGGTTATTCAAGAAAACAAAACAGTCTCTGAGATATTTAGCTTTTCAAACTGTAAATAGATGCTCTAGTGTTATTTATTTTTTTAATCCCACTTGTATTATT
TTACCTCTAGAGCATCTTGTATTAGGACATGTTATATTTATGCCAGTGGGAAATAAGTTATGGCCAAGTTTTGCAAAAACAGGAAGCAGTGAGATACTTGTTTTTTTCTCCTCACTAAATATCAGTAA
TTGTCAGGAATGGTATTACCTATTTTCATTTCCTCTTTTCAGCTTTAAGTTTTGTTGATTGGGACACTAAAACTGATGTATACCTGAGGAAAAAATAGAATGTGCTCATGGTTAGGGAAAATTATATT
ATTTTTAATTTTTTAATTTGTTTTTTAACCAAGTAGGAATTTGGGTGTATGGATAAGAGGCCAATCTGCTTCTGTAGGCTATAGAAGAAAACCAGTTGTATTTTATGGTCATAATTTGTCCCCCTATT
ATTCTGGAGATTTAAATTTAAGTAAAGTAGCCATCAGTATTTTAATTGAAAAATACTAAAGCCACATAACTGAGTAGGATGTCGTATGATACTTTCAACAAATTCCCTAATGCTGCCTAAGCATATGG
ATGTTTTAATTCTTTGCTGTTATAAATAGATATCTAATACGCCAGAATTACTGATGGTAAAATTGAAGTTGTGTAACTTGTGAATTTTTTTTATCAATGTTTTAAATATTATTTAAATCTTAAAATCA
TTTAAAGACTTATGTTGCCACTGGGTGGCAGCCATGGCTTCTCCCACTAAGCAACAGAAGTGACCAAATATAATTAAGACAAATTTTCATCTCTATTACATCTGCTTTTAAAACATTTTAGTTCATAT
TCTATTATTTTTCTAACTCAGTACTCCTTTGTTGAGGGTAATTATTAGTAGTTAAGTTTTTAATGGAAATAAAAATCATGTATGCTTATCTTTGCTGTAAAATCAAATGAATATAAATTGAGGAAAAC
TTTAAATTGTTGTAGGATGACTAGTAGTAAACATCATCTTAATTTTTAACATATATTTGATGATGCTTTCCTTTTCTCTGTATGTTTCTGGGTTTTCCCCCAGTCTTCCTTATGAAAAAAATGTATGT
TTGTAAAAAGAGAACAATTAATGCTTTGCATCACAGACATAAACTATTCATAGTAAACTGCACTGAGCTGATATTAATAGAGCAGACTTTTGAGAAAGTAGGAGTGTAGTAGCACTGGAAACAGAATG
CAAATTTCTGTTCCATAATTAGGTTTATTGTAGCTATAGCGCTCCCAGATAACCCATGTGTGCTAGTAATATCTATTGTGTGCTCTTACTATGGTATAAAAACCTCGCTGGAAGCTACTTATTTTGTA
CTTAAATATTTTACCAATTTTTAAAAAGTCTTAATCCAATGCTTATACCAGTGACTGTTTTTATAATACTTGAAGTAACTTTAAGAACTGAAACAACCCTGGAAAACTCTACATAGCTAGATAGTAAC
AATACTTGTATAAGAAACCAAGTTTCCTTATTCCCAGCCTGGTGTCTGTATCGTGACACACTACTCTGTGTATGCTTGGTTTTAGACTAGGAGGAGAGTCCTGGGAAGGGCAATATTACAGAAGTTTT
CTTCCACATGAGGAGAATGCTTAGTTTCAAATTTAAATACATGTGTCAGATGGAACCCTGCCTAACTCACTTCTACAAATAACTTCCCCAAAATCTTAGAAGGTTTTTTAGAACATGATATAAGCTTT
GTGACAAAAACAAATGCCATTGTGTCCCTTATTTAGTCATAAAACCTTAGGATTCAGCTGAATATATATTCACACATGTATATTACACATATATCACTATACAGTTAACACATGCACCTTGCACTATT
AGTGACAAATAATACTGCTAAACAAAATAGGCTTCATGCAATCTATTGCCATTGCTAGAAGAATAAATAGGCCTAGCAGATGGGCAACTTGGGTTGTTAGAATAAGGTCATTCTTGCAGAATATGGCA
CTTAAATTATCTCCAGCTGTAATGTCCTACCATATAATCCAGAGGTTGCATAGAAGCAGAGTTGTCACAGTCTCTGTAGCACGTTTGTGAGAATTCTCTAGGCAGGCCCAGCCCTTCTCTAGAAGTTT
GAATTTCACTCCCACCTTGTTGCTGGGGTACCTTCTTCAGGGTACATCTAAACACAGTGGCCTTATACAGAAATGTTGTTCAACCCACACAGTGCTTTAAAAAATTAATTGCCAACATTTAAAAATCA
GGGAGTTTCACATAAAATTCAGACTTCTTGTTTCCCTTTAAAAATGAGAAGCTAATAACATGAGTTGAATTCCCACAAGTCAACAATGAGCTGGAATCTAATATGGATGGTCCTCTTATCTTTACCAG
TGCACATGGTGAAAAAATTCAAACAGTATAATAAAGTCTTCTTTCAAGTCAAAATATA

hide sequence

RefSeq Acc Id:

NM_001291999 ⟹ NP_001278928

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	3	136,862,208 - 136,951,606 (+)	NCBI
CHM1_1	3	136,544,712 - 136,634,091 (+)	NCBI
T2T-CHM13v2.0	3	139,602,861 - 139,692,274 (+)	NCBI

Sequence:

show sequence

ACCGCGCGTGCCCCGCCTCTCTCCCAAGAGCTACGCGGCGGCGGCGGAGCGCAGGCCTCGTGCC
GTTACGGCCATCACGGCGGCCGCAGTGGCGTCCTGGAGCCCTCCTCAGGTGAGCTGGAGCTGCCCGGCTCGGCAGCGGGAAGTGCTGAAGCTGCTGAAAGATGGCAGAAGAAGTGGTGGTAGTAGCCA
AATTTGATTATGTGGCCCAACAAGAACAAGAGTTGGACATCAAGAAGAATGAGAGATTATGGCTTCTGGATGATTCTAAGTCCTGGTGGCGAGTTCGAAATTCCATGAATAAAACAGGTTTTGTGCCT
TCTAACTATGTGGAAAGGAAAAACAGTGCTCGGAAAGCATCTATTGTGAAAAACCTAAAGGATACCTTAGGCATTGGAAAAGTGAAAAGAAAACCTAGTGTGCCAGATTCTGCATCTCCTGCTGATGA
TAGTTTTGTTGACCCAGGGGAACGTCTCTATGACCTCAACATGCCCGCTTATGTGAAATTTAACTACATGGCTGAGAGAGAGGATGAATTATCATTGATAAAGGGGACAAAGGTGATCGTCATGGAGA
AATGCAGTGATGGGTGGTGGCGTGGTAGCTACAATGGACAAGTTGGATGGTTCCCTTCAAACTATGTAACTGAAGAAGGTGACAGTCCTTTGGGTGACCATGTGGGTTCTCTGTCAGAGAAATTAGCA
GCAGTCGTCAATAACCTAAATACTGGGCAAGTGTTGCATGTGGTACAGGCTCTTTACCCATTCAGCTCATCTAATGATGAAGAACTTAATTTCGAGAAAGGAGATGTAATGGATGTTATTGAAAAACC
TGAAAATGACCCAGAGTGGTGGAAATGCAGGAAGATCAATGGTATGGTTGGTCTAGTACCAAAAAACTATGTTACCGTTATGCAGAATAATCCATTAACTTCAGGTTTGGAACCATCACCTCCACAGT
GTGATTACATTAGGCCTTCACTCACTGGAAAGTTTGCTGGCAATCCTTGGTATTATGGCAAAGTCACCAGGCATCAAGCAGAAATGGCATTAAATGAAAGAGGACATGAAGGGGATTTCCTCATTCGT
GATAGTGAATCTTCGCCAAATGATTTCTCAGTATCACTAAAAGCACAAGGGAAAAACAAGCATTTTAAAGTCCAACTAAAAGAGACTGTCTACTGCATTGGGCAGCGTAAATTCAGCACCATGGAAGA
ACTTGTAGAACATTACAAAAAGGCACCAATTTTTACAAGTGAACAAGGAGAAAAATTATATCTTGTCAAGCATTTATCATGATACTGCTGACCAGAAGTGACTGCTGTGTAGCTGTAATTTGTCATGT
AATTGAAGACTGAGAAAATGTTGGGTCCAGTCGTGCTTGATTGGAAATTGTTGTTTCTAAATCTATATGAGAATTGACAATAAGTATTTTTATTATAACTCAGCCCATACATATATACTATGTATGCA
GTGCATCTGCATAGAACAGTTCCTTATCCTTGGCCTTCTGTTTTATTGTTTTTTTCTTTGCTGTTTTCCCTTTGCTTCTAATATTACAGTTTTGTATTTTGTAAACAAAAATCAAATAATGCATATCA
GAATCTTTATATGGAAGAAATCCTTTATTGCCTTTCCTTTGTTTCCTTGTAAAGGCACCCTGTTCTGTTATGGTTTTTCATTATATAAAATTATTATATCTATATATGACATATGCTAAAATTTCTTG
GAGAGTGTTAATCTTTTCTGTGACTAAATAGCAATAATAAGTGGAAAATTAGAAATTATTTCCAGGTATTATATTTGTCACAGGCCATTGTAAATACCAAGTATATTGTGTCTGCCATAATTTTTAAA
AATACATTCATTGTCTTCAGTCATACAGCAAGACACATGAGACATAGATTAGAAAACATGTTGTACAATTTTAATTTACAACTGTTGGAAATAAAAATCACTTAATTTTTTTCCAGTGCTTCTCCCTC
ATCTGGTTATTCAAGAAAACAAAACAGTCTCTGAGATATTTAGCTTTTCAAACTGTAAATAGATGCTCTAGTGTTATTTATTTTTTTAATCCCACTTGTATTATTTTACCTCTAGAGCATCTTGTATT
AGGACATGTTATATTTATGCCAGTGGGAAATAAGTTATGGCCAAGTTTTGCAAAAACAGGAAGCAGTGAGATACTTGTTTTTTTCTCCTCACTAAATATCAGTAATTGTCAGGAATGGTATTACCTAT
TTTCATTTCCTCTTTTCAGCTTTAAGTTTTGTTGATTGGGACACTAAAACTGATGTATACCTGAGGAAAAAATAGAATGTGCTCATGGTTAGGGAAAATTATATTATTTTTAATTTTTTAATTTGTTT
TTTAACCAAGTAGGAATTTGGGTGTATGGATAAGAGGCCAATCTGCTTCTGTAGGCTATAGAAGAAAACCAGTTGTATTTTATGGTCATAATTTGTCCCCCTATTATTCTGGAGATTTAAATTTAAGT
AAAGTAGCCATCAGTATTTTAATTGAAAAATACTAAAGCCACATAACTGAGTAGGATGTCGTATGATACTTTCAACAAATTCCCTAATGCTGCCTAAGCATATGGATGTTTTAATTCTTTGCTGTTAT
AAATAGATATCTAATACGCCAGAATTACTGATGGTAAAATTGAAGTTGTGTAACTTGTGAATTTTTTTTATCAATGTTTTAAATATTATTTAAATCTTAAAATCATTTAAAGACTTATGTTGCCACTG
GGTGGCAGCCATGGCTTCTCCCACTAAGCAACAGAAGTGACCAAATATAATTAAGACAAATTTTCATCTCTATTACATCTGCTTTTAAAACATTTTAGTTCATATTCTATTATTTTTCTAACTCAGTA
CTCCTTTGTTGAGGGTAATTATTAGTAGTTAAGTTTTTAATGGAAATAAAAATCATGTATGCTTATCTTTGCTGTAAAATCAAATGAATATAAATTGAGGAAAACTTTAAATTGTTGTAGGATGACTA
GTAGTAAACATCATCTTAATTTTTAACATATATTTGATGATGCTTTCCTTTTCTCTGTATGTTTCTGGGTTTTCCCCCAGTCTTCCTTATGAAAAAAATGTATGTTTGTAAAAAGAGAACAATTAATG
CTTTGCATCACAGACATAAACTATTCATAGTAAACTGCACTGAGCTGATATTAATAGAGCAGACTTTTGAGAAAGTAGGAGTGTAGTAGCACTGGAAACAGAATGCAAATTTCTGTTCCATAATTAGG
TTTATTGTAGCTATAGCGCTCCCAGATAACCCATGTGTGCTAGTAATATCTATTGTGTGCTCTTACTATGGTATAAAAACCTCGCTGGAAGCTACTTATTTTGTACTTAAATATTTTACCAATTTTTA
AAAAGTCTTAATCCAATGCTTATACCAGTGACTGTTTTTATAATACTTGAAGTAACTTTAAGAACTGAAACAACCCTGGAAAACTCTACATAGCTAGATAGTAACAATACTTGTATAAGAAACCAAGT
TTCCTTATTCCCAGCCTGGTGTCTGTATCGTGACACACTACTCTGTGTATGCTTGGTTTTAGACTAGGAGGAGAGTCCTGGGAAGGGCAATATTACAGAAGTTTTCTTCCACATGAGGAGAATGCTTA
GTTTCAAATTTAAATACATGTGTCAGATGGAACCCTGCCTAACTCACTTCTACAAATAACTTCCCCAAAATCTTAGAAGGTTTTTTAGAACATGATATAAGCTTTGTGACAAAAACAAATGCCATTGT
GTCCCTTATTTAGTCATAAAACCTTAGGATTCAGCTGAATATATATTCACACATGTATATTACACATATATCACTATACAGTTAACACATGCACCTTGCACTATTAGTGACAAATAATACTGCTAAAC
AAAATAGGCTTCATGCAATCTATTGCCATTGCTAGAAGAATAAATAGGCCTAGCAGATGGGCAACTTGGGTTGTTAGAATAAGGTCATTCTTGCAGAATATGGCACTTAAATTATCTCCAGCTGTAAT
GTCCTACCATATAATCCAGAGGTTGCATAGAAGCAGAGTTGTCACAGTCTCTGTAGCACGTTTGTGAGAATTCTCTAGGCAGGCCCAGCCCTTCTCTAGAAGTTTGAATTTCACTCCCACCTTGTTGC
TGGGGTACCTTCTTCAGGGTACATCTAAACACAGTGGCCTTATACAGAAATGTTGTTCAACCCACACAGTGCTTTAAAAAATTAATTGCCAACATTTAAAAATCAGGGAGTTTCACATAAAATTCAGA
CTTCTTGTTTCCCTTTAAAAATGAGAAGCTAATAACATGAGTTGAATTCCCACAAGTCAACAATGAGCTGGAATCTAATATGGATGGTCCTCTTATCTTTACCAGTGCACATGGTGAAAAAATTCAAA
CAGTATAATAAAGTCTTCTTTCAAGTCAAAATATA

hide sequence

RefSeq Acc Id:

NM_006153 ⟹ NP_006144

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	3	136,862,208 - 136,951,606 (+)	NCBI
GRCh37	3	136,581,050 - 136,670,446 (+)	NCBI
Build 36	3	138,063,763 - 138,150,658 (+)	NCBI Archive
HuRef	3	133,957,144 - 134,043,755 (+)	ENTREZGENE
CHM1_1	3	136,544,712 - 136,634,091 (+)	NCBI
T2T-CHM13v2.0	3	139,602,861 - 139,692,274 (+)	NCBI

Sequence:

show sequence

ACCGCGCGTGCCCCGCCTCTCTCCCAAGAGCTACGCGGCGGCGGCGGAGCGCAGGCCTCGTGCC
GTTACGGCCATCACGGCGGCCGCAGTGGCGTCCTGGAGCCCTCCTCAGTGCTGAAGCTGCTGAAAGATGGCAGAAGAAGTGGTGGTAGTAGCCAAATTTGATTATGTGGCCCAACAAGAACAAGAGTT
GGACATCAAGAAGAATGAGAGATTATGGCTTCTGGATGATTCTAAGTCCTGGTGGCGAGTTCGAAATTCCATGAATAAAACAGGTTTTGTGCCTTCTAACTATGTGGAAAGGAAAAACAGTGCTCGGA
AAGCATCTATTGTGAAAAACCTAAAGGATACCTTAGGCATTGGAAAAGTGAAAAGAAAACCTAGTGTGCCAGATTCTGCATCTCCTGCTGATGATAGTTTTGTTGACCCAGGGGAACGTCTCTATGAC
CTCAACATGCCCGCTTATGTGAAATTTAACTACATGGCTGAGAGAGAGGATGAATTATCATTGATAAAGGGGACAAAGGTGATCGTCATGGAGAAATGCAGTGATGGGTGGTGGCGTGGTAGCTACAA
TGGACAAGTTGGATGGTTCCCTTCAAACTATGTAACTGAAGAAGGTGACAGTCCTTTGGGTGACCATGTGGGTTCTCTGTCAGAGAAATTAGCAGCAGTCGTCAATAACCTAAATACTGGGCAAGTGT
TGCATGTGGTACAGGCTCTTTACCCATTCAGCTCATCTAATGATGAAGAACTTAATTTCGAGAAAGGAGATGTAATGGATGTTATTGAAAAACCTGAAAATGACCCAGAGTGGTGGAAATGCAGGAAG
ATCAATGGTATGGTTGGTCTAGTACCAAAAAACTATGTTACCGTTATGCAGAATAATCCATTAACTTCAGGTTTGGAACCATCACCTCCACAGTGTGATTACATTAGGCCTTCACTCACTGGAAAGTT
TGCTGGCAATCCTTGGTATTATGGCAAAGTCACCAGGCATCAAGCAGAAATGGCATTAAATGAAAGAGGACATGAAGGGGATTTCCTCATTCGTGATAGTGAATCTTCGCCAAATGATTTCTCAGTAT
CACTAAAAGCACAAGGGAAAAACAAGCATTTTAAAGTCCAACTAAAAGAGACTGTCTACTGCATTGGGCAGCGTAAATTCAGCACCATGGAAGAACTTGTAGAACATTACAAAAAGGCACCAATTTTT
ACAAGTGAACAAGGAGAAAAATTATATCTTGTCAAGCATTTATCATGATACTGCTGACCAGAAGTGACTGCTGTGTAGCTGTAATTTGTCATGTAATTGAAGACTGAGAAAATGTTGGGTCCAGTCGT
GCTTGATTGGAAATTGTTGTTTCTAAATCTATATGAGAATTGACAATAAGTATTTTTATTATAACTCAGCCCATACATATATACTATGTATGCAGTGCATCTGCATAGAACAGTTCCTTATCCTTGGC
CTTCTGTTTTATTGTTTTTTTCTTTGCTGTTTTCCCTTTGCTTCTAATATTACAGTTTTGTATTTTGTAAACAAAAATCAAATAATGCATATCAGAATCTTTATATGGAAGAAATCCTTTATTGCCTT
TCCTTTGTTTCCTTGTAAAGGCACCCTGTTCTGTTATGGTTTTTCATTATATAAAATTATTATATCTATATATGACATATGCTAAAATTTCTTGGAGAGTGTTAATCTTTTCTGTGACTAAATAGCAA
TAATAAGTGGAAAATTAGAAATTATTTCCAGGTATTATATTTGTCACAGGCCATTGTAAATACCAAGTATATTGTGTCTGCCATAATTTTTAAAAATACATTCATTGTCTTCAGTCATACAGCAAGAC
ACATGAGACATAGATTAGAAAACATGTTGTACAATTTTAATTTACAACTGTTGGAAATAAAAATCACTTAATTTTTTTCCAGTGCTTCTCCCTCATCTGGTTATTCAAGAAAACAAAACAGTCTCTGA
GATATTTAGCTTTTCAAACTGTAAATAGATGCTCTAGTGTTATTTATTTTTTTAATCCCACTTGTATTATTTTACCTCTAGAGCATCTTGTATTAGGACATGTTATATTTATGCCAGTGGGAAATAAG
TTATGGCCAAGTTTTGCAAAAACAGGAAGCAGTGAGATACTTGTTTTTTTCTCCTCACTAAATATCAGTAATTGTCAGGAATGGTATTACCTATTTTCATTTCCTCTTTTCAGCTTTAAGTTTTGTTG
ATTGGGACACTAAAACTGATGTATACCTGAGGAAAAAATAGAATGTGCTCATGGTTAGGGAAAATTATATTATTTTTAATTTTTTAATTTGTTTTTTAACCAAGTAGGAATTTGGGTGTATGGATAAG
AGGCCAATCTGCTTCTGTAGGCTATAGAAGAAAACCAGTTGTATTTTATGGTCATAATTTGTCCCCCTATTATTCTGGAGATTTAAATTTAAGTAAAGTAGCCATCAGTATTTTAATTGAAAAATACT
AAAGCCACATAACTGAGTAGGATGTCGTATGATACTTTCAACAAATTCCCTAATGCTGCCTAAGCATATGGATGTTTTAATTCTTTGCTGTTATAAATAGATATCTAATACGCCAGAATTACTGATGG
TAAAATTGAAGTTGTGTAACTTGTGAATTTTTTTTATCAATGTTTTAAATATTATTTAAATCTTAAAATCATTTAAAGACTTATGTTGCCACTGGGTGGCAGCCATGGCTTCTCCCACTAAGCAACAG
AAGTGACCAAATATAATTAAGACAAATTTTCATCTCTATTACATCTGCTTTTAAAACATTTTAGTTCATATTCTATTATTTTTCTAACTCAGTACTCCTTTGTTGAGGGTAATTATTAGTAGTTAAGT
TTTTAATGGAAATAAAAATCATGTATGCTTATCTTTGCTGTAAAATCAAATGAATATAAATTGAGGAAAACTTTAAATTGTTGTAGGATGACTAGTAGTAAACATCATCTTAATTTTTAACATATATT
TGATGATGCTTTCCTTTTCTCTGTATGTTTCTGGGTTTTCCCCCAGTCTTCCTTATGAAAAAAATGTATGTTTGTAAAAAGAGAACAATTAATGCTTTGCATCACAGACATAAACTATTCATAGTAAA
CTGCACTGAGCTGATATTAATAGAGCAGACTTTTGAGAAAGTAGGAGTGTAGTAGCACTGGAAACAGAATGCAAATTTCTGTTCCATAATTAGGTTTATTGTAGCTATAGCGCTCCCAGATAACCCAT
GTGTGCTAGTAATATCTATTGTGTGCTCTTACTATGGTATAAAAACCTCGCTGGAAGCTACTTATTTTGTACTTAAATATTTTACCAATTTTTAAAAAGTCTTAATCCAATGCTTATACCAGTGACTG
TTTTTATAATACTTGAAGTAACTTTAAGAACTGAAACAACCCTGGAAAACTCTACATAGCTAGATAGTAACAATACTTGTATAAGAAACCAAGTTTCCTTATTCCCAGCCTGGTGTCTGTATCGTGAC
ACACTACTCTGTGTATGCTTGGTTTTAGACTAGGAGGAGAGTCCTGGGAAGGGCAATATTACAGAAGTTTTCTTCCACATGAGGAGAATGCTTAGTTTCAAATTTAAATACATGTGTCAGATGGAACC
CTGCCTAACTCACTTCTACAAATAACTTCCCCAAAATCTTAGAAGGTTTTTTAGAACATGATATAAGCTTTGTGACAAAAACAAATGCCATTGTGTCCCTTATTTAGTCATAAAACCTTAGGATTCAG
CTGAATATATATTCACACATGTATATTACACATATATCACTATACAGTTAACACATGCACCTTGCACTATTAGTGACAAATAATACTGCTAAACAAAATAGGCTTCATGCAATCTATTGCCATTGCTA
GAAGAATAAATAGGCCTAGCAGATGGGCAACTTGGGTTGTTAGAATAAGGTCATTCTTGCAGAATATGGCACTTAAATTATCTCCAGCTGTAATGTCCTACCATATAATCCAGAGGTTGCATAGAAGC
AGAGTTGTCACAGTCTCTGTAGCACGTTTGTGAGAATTCTCTAGGCAGGCCCAGCCCTTCTCTAGAAGTTTGAATTTCACTCCCACCTTGTTGCTGGGGTACCTTCTTCAGGGTACATCTAAACACAG
TGGCCTTATACAGAAATGTTGTTCAACCCACACAGTGCTTTAAAAAATTAATTGCCAACATTTAAAAATCAGGGAGTTTCACATAAAATTCAGACTTCTTGTTTCCCTTTAAAAATGAGAAGCTAATA
ACATGAGTTGAATTCCCACAAGTCAACAATGAGCTGGAATCTAATATGGATGGTCCTCTTATCTTTACCAGTGCACATGGTGAAAAAATTCAAACAGTATAATAAAGTCTTCTTTCAAGTCAAAATAT
A

hide sequence

RefSeq Acc Id:

XM_024453538 ⟹ XP_024309306

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	3	136,862,449 - 136,951,606 (+)	NCBI

Sequence:

show sequence

AGCCGGAGGGGGCGCGGAGGCTGCTCGGAGGGTCCAGACTTCTGCACCGGGATTCCGCGAGACC
CTCGGGCCGTTGCCCCAGGGAGCGTGACCCCGCGGCCTCCTTGTCAGCCCCTGGAGCGCTGTGTCGGGCTGAGAGCCCGGGCGGCCGCCCGTGCGAGCCTGGGAGGTCGAGTGTGCGGCGCGCTGGTT
GACTTGTCTGTTTTCTCATGAAAAAGTCCTTTTGCCAGCTGTGGCGTAATCCGAGGCCGGGAAGTGCTGAAGCTGCTGAAAGATGGCAGAAGAAGTGGTGGTAGTAGCCAAATTTGATTATGTGGCCC
AACAAGAACAAGAGTTGGACATCAAGAAGAATGAGAGATTATGGCTTCTGGATGATTCTAAGTCCTGGTGGCGAGTTCGAAATTCCATGAATAAAACAGGTTTTGTGCCTTCTAACTATGTGGAAAGG
AAAAACAGTGCTCGGAAAGCATCTATTGTGAAAAACCTAAAGGATACCTTAGGCATTGGAAAAGTGAAAAGAAAACCTAGTGTGCCAGATTCTGCATCTCCTGCTGATGATAGTTTTGTTGACCCAGG
GGAACGTCTCTATGACCTCAACATGCCCGCTTATGTGAAATTTAACTACATGGCTGAGAGAGAGGATGAATTATCATTGATAAAGGGGACAAAGGTGATCGTCATGGAGAAATGCAGTGATGGGTGGT
GGCGTGGTAGCTACAATGGACAAGTTGGATGGTTCCCTTCAAACTATGTAACTGAAGAAGGTGACAGTCCTTTGGGTGACCATGTGGGTTCTCTGTCAGAGAAATTAGCAGCAGTCGTCAATAACCTA
AATACTGGGCAAGTGTTGCATGTGGTACAGGCTCTTTACCCATTCAGCTCATCTAATGATGAAGAACTTAATTTCGAGAAAGGAGATGTAATGGATGTTATTGAAAAACCTGAAAATGACCCAGAGTG
GTGGAAATGCAGGAAGATCAATGGTATGGTTGGTCTAGTACCAAAAAACTATGTTACCGTTATGCAGAATAATCCATTAACTTCAGGTTTGGAACCATCACCTCCACAGTGTGATTACATTAGGCCTT
CACTCACTGGAAAGTTTGCTGGCAATCCTTGGTATTATGGCAAAGTCACCAGGCATCAAGCAGAAATGGCATTAAATGAAAGAGGACATGAAGGGGATTTCCTCATTCGTGATAGTGAATCTTCGCCA
AATGATTTCTCAGTATCACTAAAAGCACAAGGGAAAAACAAGCATTTTAAAGTCCAACTAAAAGAGACTGTCTACTGCATTGGGCAGCGTAAATTCAGCACCATGGAAGAACTTGTAGAACATTACAA
AAAGGCACCAATTTTTACAAGTGAACAAGGAGAAAAATTATATCTTGTCAAGCATTTATCATGATACTGCTGACCAGAAGTGACTGCTGTGTAGCTGTAATTTGTCATGTAATTGAAGACTGAGAAAA
TGTTGGGTCCAGTCGTGCTTGATTGGAAATTGTTGTTTCTAAATCTATATGAGAATTGACAATAAGTATTTTTATTATAACTCAGCCCATACATATATACTATGTATGCAGTGCATCTGCATAGAACA
GTTCCTTATCCTTGGCCTTCTGTTTTATTGTTTTTTTCTTTGCTGTTTTCCCTTTGCTTCTAATATTACAGTTTTGTATTTTGTAAACAAAAATCAAATAATGCATATCAGAATCTTTATATGGAAGA
AATCCTTTATTGCCTTTCCTTTGTTTCCTTGTAAAGGCACCCTGTTCTGTTATGGTTTTTCATTATATAAAATTATTATATCTATATATGACATATGCTAAAATTTCTTGGAGAGTGTTAATCTTTTC
TGTGACTAAATAGCAATAATAAGTGGAAAATTAGAAATTATTTCCAGGTATTATATTTGTCACAGGCCATTGTAAATACCAAGTATATTGTGTCTGCCATAATTTTTAAAAATACATTCATTGTCTTC
AGTCATACAGCAAGACACATGAGACATAGATTAGAAAACATGTTGTACAATTTTAATTTACAACTGTTGGAAATAAAAATCACTTAATTTTTTTCCAGTG

hide sequence

RefSeq Acc Id:

XM_047448189 ⟹ XP_047304145

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	3	136,862,208 - 136,951,606 (+)	NCBI

RefSeq Acc Id:

XM_047448190 ⟹ XP_047304146

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	3	136,912,844 - 136,951,606 (+)	NCBI

RefSeq Acc Id:

XM_047448191 ⟹ XP_047304147

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	3	136,863,146 - 136,951,606 (+)	NCBI

RefSeq Acc Id:

XM_054346631 ⟹ XP_054202606

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	3	139,603,102 - 139,692,274 (+)	NCBI

RefSeq Acc Id:

XM_054346632 ⟹ XP_054202607

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	3	139,602,861 - 139,692,274 (+)	NCBI

RefSeq Acc Id:

XM_054346633 ⟹ XP_054202608

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	3	139,603,569 - 139,692,274 (+)	NCBI

RefSeq Acc Id:

XM_054346634 ⟹ XP_054202609

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	3	139,653,543 - 139,692,274 (+)	NCBI


Protein RefSeqs	NP_001177725	(Get FASTA)	NCBI Sequence Viewer
	NP_001278928	(Get FASTA)	NCBI Sequence Viewer
	NP_006144	(Get FASTA)	NCBI Sequence Viewer
	XP_024309306	(Get FASTA)	NCBI Sequence Viewer
	XP_047304145	(Get FASTA)	NCBI Sequence Viewer
	XP_047304146	(Get FASTA)	NCBI Sequence Viewer
	XP_047304147	(Get FASTA)	NCBI Sequence Viewer
	XP_054202606	(Get FASTA)	NCBI Sequence Viewer
	XP_054202607	(Get FASTA)	NCBI Sequence Viewer
	XP_054202608	(Get FASTA)	NCBI Sequence Viewer
	XP_054202609	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH06403	(Get FASTA)	NCBI Sequence Viewer
	ALQ33676	(Get FASTA)	NCBI Sequence Viewer
	ALQ33677	(Get FASTA)	NCBI Sequence Viewer
	ALQ33678	(Get FASTA)	NCBI Sequence Viewer
	BAG35571	(Get FASTA)	NCBI Sequence Viewer
	BAH13487	(Get FASTA)	NCBI Sequence Viewer
	CAA35599	(Get FASTA)	NCBI Sequence Viewer
	EAW79105	(Get FASTA)	NCBI Sequence Viewer
	EAW79106	(Get FASTA)	NCBI Sequence Viewer
	EAW79107	(Get FASTA)	NCBI Sequence Viewer
	EAW79108	(Get FASTA)	NCBI Sequence Viewer
	EAW79109	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000288986
	ENSP00000288986.2
	ENSP00000417273
	ENSP00000417273.1
	ENSP00000419631
	ENSP00000419631.1
GenBank Protein	P16333	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_006144 ⟸ NM_006153
- Peptide Label:	isoform 1
- UniProtKB:	B7Z751 (UniProtKB/Swiss-Prot), D3DNE3 (UniProtKB/Swiss-Prot), P16333 (UniProtKB/Swiss-Prot), A0A0S2Z4Y3 (UniProtKB/TrEMBL), B2R6S4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAEEVVVVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERKNSARKASIVKNLKDTLGIGKVKRKPSVPDSASPADDSFVDPGERLYDLNMPAYVKFNYMAEREDELSLI KGTKVIVMEKCSDGWWRGSYNGQVGWFPSNYVTEEGDSPLGDHVGSLSEKLAAVVNNLNTGQVLHVVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNYVTVMQNNPLT SGLEPSPPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCIGQRKFSTMEELVEHYKKAPIFTSEQGEKLYLVKHLS hide sequence

RefSeq Acc Id:	NP_001177725 ⟸ NM_001190796
- Peptide Label:	isoform 2
- UniProtKB:	B2R6S4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDWLNVFKDFFSIGKVKRKPSVPDSASPADDSFVDPGERLYDLNMPAYVKFNYMAEREDELSLIKGTKVIVMEKCSDGWWRGSYNGQVGWFPSNYVTEEGDSPLGDHVGSLSEKLAAVVNNLNTGQVL HVVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNYVTVMQNNPLTSGLEPSPPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVS LKAQGKNKHFKVQLKETVYCIGQRKFSTMEELVEHYKKAPIFTSEQGEKLYLVKHLS hide sequence

RefSeq Acc Id:	NP_001278928 ⟸ NM_001291999
- Peptide Label:	isoform 1
- UniProtKB:	B7Z751 (UniProtKB/Swiss-Prot), D3DNE3 (UniProtKB/Swiss-Prot), P16333 (UniProtKB/Swiss-Prot), A0A0S2Z4Y3 (UniProtKB/TrEMBL), B2R6S4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAEEVVVVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERKNSARK ASIVKNLKDTLGIGKVKRKPSVPDSASPADDSFVDPGERLYDLNMPAYVKFNYMAEREDELSLIKGTKVIVMEKCSDGWWRGSYNGQVGWFPSNYVTEEGDSPLGDHVGSLSEKLAAVVNNLNTGQVL HVVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNYVTVMQNNPLTSGLEPSPPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVS LKAQGKNKHFKVQLKETVYCIGQRKFSTMEELVEHYKKAPIFTSEQGEKLYLVKHLS hide sequence

RefSeq Acc Id:	XP_024309306 ⟸ XM_024453538
- Peptide Label:	isoform X1
- UniProtKB:	P16333 (UniProtKB/Swiss-Prot), B7Z751 (UniProtKB/Swiss-Prot), D3DNE3 (UniProtKB/Swiss-Prot), A0A0S2Z4Y3 (UniProtKB/TrEMBL), B2R6S4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAEEVVVVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERKNSARK ASIVKNLKDTLGIGKVKRKPSVPDSASPADDSFVDPGERLYDLNMPAYVKFNYMAEREDELSLIKGTKVIVMEKCSDGWWRGSYNGQVGWFPSNYVTEEGDSPLGDHVGSLSEKLAAVVNNLNTGQVL HVVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNYVTVMQNNPLTSGLEPSPPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVS LKAQGKNKHFKVQLKETVYCIGQRKFSTMEELVEHYKKAPIFTSEQGEKLYLVKHLS hide sequence

Ensembl Acc Id:

ENSP00000419302 ⟸ ENST00000491539

Protein Domains

SH2 SH3

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P16333-F1-model_v2	AlphaFold	P16333	1-377	view protein structure

RGD ID:

6865784

Promoter ID:

EPDNEW_H6057

Type:

initiation region

Name:

NCK1_1

Description:

NCK adaptor protein 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H6055

Experiment Methods:

Single-end sequencing.; Paired-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	3	136,862,233 - 136,862,293	EPDNEW

RGD ID:

6801332

Promoter ID:

HG_KWN:46292

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell, CD4+TCell_12Hour, CD4+TCell_2Hour, HeLa_S3, Jurkat, K562, Lymphoblastoid, NB4

Transcripts:

NM_006153

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	3	138,063,541 - 138,064,187 (+)	MPROMDB

Database	Acc Id	Source(s)
COSMIC	NCK1	COSMIC
Ensembl Genes	ENSG00000158092	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000288986	ENTREZGENE
	ENST00000288986.6	UniProtKB/Swiss-Prot
	ENST00000469404	ENTREZGENE
	ENST00000469404.1	UniProtKB/Swiss-Prot
	ENST00000481752	ENTREZGENE
	ENST00000481752.6	UniProtKB/Swiss-Prot
Gene3D-CATH	3.30.505.10	UniProtKB/Swiss-Prot
	SH3 Domains	UniProtKB/Swiss-Prot
GTEx	ENSG00000158092	GTEx
HGNC ID	HGNC:7664	ENTREZGENE
Human Proteome Map	NCK1	Human Proteome Map
InterPro	NCK	UniProtKB/Swiss-Prot
	Nck1_SH2	UniProtKB/Swiss-Prot
	Nck1_SH3_1	UniProtKB/Swiss-Prot
	Nck1_SH3_2	UniProtKB/Swiss-Prot
	Nck1_SH3_3	UniProtKB/Swiss-Prot
	SH2	UniProtKB/Swiss-Prot
	SH2_dom_sf	UniProtKB/Swiss-Prot
	SH3-like_dom_sf	UniProtKB/Swiss-Prot
	SH3_domain	UniProtKB/Swiss-Prot
	Tyrosine-phos_adapter	UniProtKB/Swiss-Prot
KEGG Report	hsa:4690	UniProtKB/Swiss-Prot
NCBI Gene	4690	ENTREZGENE
OMIM	600508	OMIM
PANTHER	PTHR19969:SF16	UniProtKB/Swiss-Prot
	SH2-SH3 ADAPTOR PROTEIN-RELATED	UniProtKB/Swiss-Prot
Pfam	SH2	UniProtKB/Swiss-Prot
	SH3_1	UniProtKB/Swiss-Prot
PharmGKB	PA31466	PharmGKB
PIRSF	Cytoplasmic_NCK	UniProtKB/Swiss-Prot
PRINTS	SH2DOMAIN	UniProtKB/Swiss-Prot
	SH3DOMAIN	UniProtKB/Swiss-Prot
PROSITE	SH2	UniProtKB/Swiss-Prot
	SH3	UniProtKB/Swiss-Prot
SMART	SH2	UniProtKB/Swiss-Prot
	SH3	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF50044	UniProtKB/Swiss-Prot
	SSF55550	UniProtKB/Swiss-Prot
UniProt	A0A0S2Z4D7_HUMAN	UniProtKB/TrEMBL
	A0A0S2Z4E4_HUMAN	UniProtKB/TrEMBL
	A0A0S2Z4Y3	ENTREZGENE, UniProtKB/TrEMBL
	B2R6S4	ENTREZGENE, UniProtKB/TrEMBL
	B7Z751	ENTREZGENE
	C9J0K5_HUMAN	UniProtKB/TrEMBL
	C9J869_HUMAN	UniProtKB/TrEMBL
	C9JAB9_HUMAN	UniProtKB/TrEMBL
	C9JVV5_HUMAN	UniProtKB/TrEMBL
	C9K098_HUMAN	UniProtKB/TrEMBL
	D3DNE3	ENTREZGENE
	H7C5C7_HUMAN	UniProtKB/TrEMBL
	NCK1_HUMAN	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	B7Z751	UniProtKB/Swiss-Prot
	D3DNE3	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

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Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)