RAB4A (RAB4A, member RAS oncogene family)

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Gene: RAB4A (RAB4A, member RAS oncogene family) Pan paniscus

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Symbol:

RAB4A

Name:

RAB4A, member RAS oncogene family

RGD ID:

11737382

Description:

ENCODES a protein that exhibits ATPase activator activity (ortholog); ATPase binding (ortholog); GTP binding (ortholog); INVOLVED IN neurotransmitter receptor transport postsynaptic membrane to endosome (ortholog); protein transport (ortholog); Rab protein signal transduction (ortholog); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; platelet-derived growth factor signaling pathway; Rab family mediated signaling pathway; ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); parathyroid carcinoma (ortholog); FOUND IN glutamatergic synapse (ortholog); insulin-responsive compartment (ortholog); recycling endosome (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ras-related protein Rab-4A; S-phase response (cyclin related); SPHAR

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	19,907,239 - 19,942,434 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	20,099,505 - 20,130,356 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	204,818,445 - 204,849,775 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	209,848,620 - 209,883,305 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	209,848,620 - 209,883,305 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

gastrointestinal stromal tumor (ISO)

parathyroid carcinoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

antigen processing and presentation (IEA)

neurotransmitter receptor transport postsynaptic membrane to endosome (ISO)

protein transport (IEA,ISO)

Rab protein signal transduction (IEA,ISO)

regulation of endocytosis (IEA,ISO)

small GTPase-mediated signal transduction (ISO)

vesicle-mediated transport in synapse (ISO)

Cellular Component

cytoplasm (IEA)

cytoplasmic vesicle membrane (IEA)

early endosome membrane (IEA)

endomembrane system (IEA)

endosome (IEA)

extracellular exosome (IEA)

glutamatergic synapse (ISO)

insulin-responsive compartment (ISO)

membrane (IEA)

perinuclear region of cytoplasm (IEA)

plasma membrane (IEA)

recycling endosome (ISO)

recycling endosome membrane (IEA)

synaptic vesicle membrane (ISO)

vesicle (IEA)

Molecular Function

ATPase activator activity (ISO)

ATPase binding (ISO)

G protein activity (IEA)

GDP binding (IEA)

GTP binding (IEA,ISO)

GTPase activity (IEA,ISO)

hydrolase activity (IEA)

ionotropic glutamate receptor binding (ISO)

protein binding (ISO)

syntaxin binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

insulin responsive facilitative sugar transporter mediated glucose transport pathway (ISO)

platelet-derived growth factor signaling pathway (ISO)

Rab family mediated signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

RAB4A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	19,907,239 - 19,942,434 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	20,099,505 - 20,130,356 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	204,818,445 - 204,849,775 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	209,848,620 - 209,883,305 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	209,848,620 - 209,883,305 (+)	Ensembl	panpan1.1		panPan2

RAB4A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	229,271,111 - 229,305,894 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	229,271,062 - 229,305,894 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	229,406,858 - 229,441,641 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	227,473,502 - 227,507,141 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	225,713,613 - 225,747,252	NCBI
Celera	1	202,675,200 - 202,708,836 (+)	NCBI		Celera
Cytogenetic Map	1	q42.13	NCBI
HuRef	1	199,897,464 - 199,932,284 (+)	NCBI		HuRef
CHM1_1	1	230,679,139 - 230,713,964 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	228,649,787 - 228,684,556 (+)	NCBI		T2T-CHM13v2.0

Rab4a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	124,532,748 - 124,562,030 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	124,532,724 - 124,562,026 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	123,805,846 - 123,835,291 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	123,805,985 - 123,835,287 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	126,329,896 - 126,359,191 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	126,692,115 - 126,721,377 (+)	NCBI		MGSCv36	mm8
Celera	8	128,073,037 - 128,102,572 (+)	NCBI		Celera
Cytogenetic Map	8	E2	NCBI
cM Map	8	72.19	NCBI

Rab4a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	68,692,228 - 68,720,169 (+)	NCBI		GRCr8
mRatBN7.2	19	51,795,613 - 51,822,706 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	51,795,613 - 51,822,703 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	58,586,931 - 58,614,024 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	59,431,649 - 59,458,731 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	61,513,357 - 61,540,448 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	56,585,598 - 56,613,078 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	56,585,767 - 56,613,075 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	67,296,402 - 67,323,425 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	53,991,122 - 54,019,248 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	53,996,067 - 54,022,738 (+)	NCBI
Celera	19	51,171,470 - 51,198,520 (+)	NCBI		Celera
Cytogenetic Map	19	q12	NCBI

Rab4a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955492	8,713,968 - 8,743,434 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955492	8,715,252 - 8,743,432 (-)	NCBI	ChiLan1.0	ChiLan1.0

RAB4A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	9,914,681 - 9,965,468 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	9,916,235 - 9,965,469 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	9,906,049 - 9,956,928 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	9,945,626 - 9,996,957 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	9,941,226 - 9,997,643 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	9,949,479 - 10,000,571 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	10,063,339 - 10,113,821 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	10,316,763 - 10,367,878 (-)	NCBI		UU_Cfam_GSD_1.0

Rab4a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	44,116,269 - 44,136,517 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936484	20,281,435 - 20,301,391 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936484	20,281,495 - 20,301,906 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RAB4A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	60,481,488 - 60,529,095 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	60,481,484 - 60,528,549 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	65,322,929 - 65,370,292 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RAB4A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	66,540,462 - 66,574,729 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	66,540,549 - 66,572,173 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	68,386,203 - 68,420,443 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rab4a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624775	19,739,086 - 19,762,436 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624775	19,738,220 - 19,762,351 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003824456	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008978164	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034948632	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034948636	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034948641	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055104111	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000049910 ⟹ ENSPPAP00000027074

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	1	209,848,620 - 209,883,305 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000049923 ⟹ ENSPPAP00000027087

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	1	209,860,440 - 209,880,773 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000049930 ⟹ ENSPPAP00000027094

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	1	209,863,294 - 209,880,773 (+)	Ensembl

RefSeq Acc Id:

XM_003824456 ⟹ XP_003824504

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	19,907,239 - 19,942,434 (-)	NCBI
NHGRI_mPanPan1	1	20,099,505 - 20,130,356 (-)	NCBI
Mhudiblu_PPA_v0	1	204,818,472 - 204,849,771 (+)	NCBI
PanPan1.1	1	209,848,620 - 209,883,305 (+)	NCBI

Sequence:

show sequence

CACGCGCGAACGCGGGTGGCCGGCCTCGCGTAGCCCATCTCCTCTTCCTCCTCGCGGTCGCGGC
CGGACGGAGGGTGGAGGGCCCTGCGCCTGCGCGGAGCTGGAGTCCGGCTGGGCCGCAGCCGCTG
GGAGACCGGCGGTTGCCGTGGGGACCGGTCGGGCCCCTCCCTCCTCCGGTCCCCCGCCCCAGGT
CCATCCCCACCGAGACGCGCCGGCGGACCGCGGGCGAGTGCAGCCGGTGACCCGGCGAGAGGCG
GCGCCGCTCCCAAGATGTCGCAGACGGCCATGTCCGAAACCTACGATTTTTTGTTTAAGTTCTT
GGTTATTGGAAATGCAGGAACTGGCAAATCTTGCTTACTTCATCAGTTTATTGAAAAAAAATTC
AAAGATGACTCAAATCATACAATAGGAGTGGAATTTGGTTCAAAGATAATAAATGTTGGTGGTA
AATATGTAAAGTTACAAATATGGGATACAGCAGGACAAGAACGATTCAGGTCCGTGACGAGAAG
TTATTACCGAGGCGCGGCCGGGGCTCTCCTCGTCTATGATATCACCAGCCGAGAAACCTACAAT
GCGCTTACTAATTGGTTAACAGATGCCCGAATGCTAGCGAGCCAGAACATTGTGATCATCCTTT
GTGGAAACAAGAAGGACCTGGATGCAGATCGTGAAGTTACCTTCTTAGAAGCCTCCAGATTTGC
TCAAGAAAATGAGCTGATGTTTTTGGAAACAAGTGCGCTCACAGGGGAGAATGTAGAAGAGGCT
TTTGTACAGTGTGCAAGAAAAATACTTAACAAAATCGAATCAGGTGAGCTGGACCCAGAAAGAA
TGGGCTCAGGTATTCAGTATGGAGATGCTGCCTTGAGACAGCTGAGGTCACCGCGGCGCGCACA
GGCCCCGAACGCTCAGGAGTGTGGTTGTTAGGAGCCATGGGAGAACACACAGGTGTTCATACAG
TGGCATTTGGGACACAATCGTTGGAACCTGAAGAATCTGAAGTTTTTTTTACCACCATCCTTTT
CTACTCTGTATGGAAGTAGATCTTTATGGGGAAAAGAGAATTTGGGGTGTTCTGCAAGCTAGTC
AAAGTGGCACAGCAAATCATATAAATCGAATTAAATGGACAACACCGTTAGATGTGTATGTAAA
AATTTTGTTTCATATTTTTCCTTTCACTTTCGGTTTAAAACATGCTATATGTACTGTATGTCCT
GTAGCCCAGTGCAGCTCCACAGCATGGAATCTGATGTATGATATGATAGAATGTGGCACTAAAT
GCAGTTTCAGATTTTATTTTTTTTAATGATATGAACTAAAATTGTCAATTGTGAGGTGTGCTTT
TCTCATCATGTTGGTTATATTGCACAATTGGTTATATTTATGACCTGATATTCAAAGACTCTGG
CATTGATAGCCAGTGTGTTTTCTTATTTAATTCCATTTACTACATTCTACATGGTGTTTACGTG
ATCCACACTTGAAATACTAGATCAGTAGACATTCACTAATATACCAAAATAAAATGAAAAATGG
AGTTTTTCCGTGAACTTTATACTGTCCAGCTCTGTTGATTTTAAAGCCTCTTCATCCAGGTCAG
TTCAGGAAGTATATCTGGAGTACCTGCTCTGTTTTTGGCTGTGAGACTAGCACTAAGGATTCTG
GTACCTTTACCCAAACCTACTGGGCTACTAATACTTCTCTCAGCAGTTGATCAAATACAATAGA
CCATGTAAGCTGGGGCCGCTCATCCACTTCCAGTTTGCTGGTCTCCCTGCTAGAAAACACATTG
TACTGTGCTTTTTCTGGAATTCAGTATAATGGCATCACTGCCTGTTTTTCACACCTTTGGTTTC
CTGTTCATTTTAAGGAAACCTACTAAATCCAGTTAATATTAAATGGACACCACTCATTAAGAAA
TTTCTTTATGGCTTCTGCTGAATACTTAAATGCCTTACTACAGTTATCCAGTTGACATGTTTTT
AATTCATATAAGGTATATTGGGTATATTGAAGTATATATTGTATTACAAAGACTTGTTCTTGTA
TTTTAAAATGTCAGTGCAAAAAATATATGGTGGAACCTTTCTTTAAAGTTGAAATGCAGTATTA
TTTAAATCTGAAAGGTTAAAAAGCTTTCTTCACCTTATATATGTTCTTCCACTGTGACTTTGTA
GTTGAAGACTAGTAAATTAACTTTTAGTTAGAAGATGCCTACTGCTTTTGTTGTTTATTTTAGT
CAGCAGAGCACAGAGACACATAAAAACTCTGGGAAATGACTGGGATAAAAATATCAGTATGTAT
CTGTTTTAGATATTTTGAGTTTTGCTTTTTTTATGCCTTGAATATTTTATTTCAAAAAGTATCT
GAAGCAAATTCTCAGACTGAACTACTTCTTAGACCTCACTGTAAGAATGTTTTATTCAATGTCT
CATTTATGATAGATTTGCAAGCTGCTCATTTTTGAACAGCTTTTTGCATGGGATAGGAGCATGT
CTATTCTAACACATCAGCTTATTCAAAAGCAAGAATTTTGAAAATAAGATAAATGTAAAGTTGT
TTTATAAACGATCCTGTTAATTAAACCACAGACACCATATATCCTTCTGCATCCTTTGGCCAAT
AAAAGTTGCTGGAGAACCAAA

hide sequence

RefSeq Acc Id:

XM_008978164 ⟹ XP_008976412

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	19,907,239 - 19,942,398 (-)	NCBI
NHGRI_mPanPan1	1	20,099,505 - 20,130,337 (-)	NCBI
Mhudiblu_PPA_v0	1	204,818,445 - 204,849,775 (+)	NCBI
PanPan1.1	1	209,848,620 - 209,883,305 (+)	NCBI

Sequence:

show sequence

CACGCGCGAACGCGGGTGGCCGGCCTCGCGTAGCCCATCTCCTCTTCCTCCTCGCGGTCGCGGC
CGGACGGAGGGTGGAGGGCCCTGCGCCTGCGCGGAGCTGGAGTCCGGCTGGGCCGCAGCCGCTG
GGAGACCGGCGGTTGCCGTGGGGACCGGTCGGGCCCCTCCCTCCTCCGGTCCCCCGCCCCAGGT
CCATCCCCACCGAGACGCGCCGGCGGACCGCGGGCGAGTGCAGCCGGTGACCCGGCGAGAGGCG
GCGCCGCTCCCAAGATGTCGCAGACGGCCATGTCCGAAACCTACGGTCCGTGACGAGAAGTTAT
TACCGAGGCGCGGCCGGGGCTCTCCTCGTCTATGATATCACCAGATGCCCGAATGCTAGCGAGC
CAGAACATTGTGATCATCCTTTGTGGAAACAAGAAGGACCTGGATGCAGATCGTGAAGTTACCT
TCTTAGAAGCCTCCAGATTTGCTCAAGAAAATGAGCTGATGTTTTTGGAAACAAGTGCGCTCAC
AGGGGAGAATGTAGAAGAGGCTTTTGTACAGTGTGCAAGAAAAATACTTAACAAAATCGAATCA
GGTGAGCTGGACCCAGAAAGAATGGGCTCAGGTATTCAGTATGGAGATGCTGCCTTGAGACAGC
TGAGGTCACCGCGGCGCGCACAGGCCCCGAACGCTCAGGAGTGTGGTTGTTAGGAGCCATGGGA
GAACACACAGGTGTTCATACAGTGGCATTTGGGACACAATCGTTGGAACCTGAAGAATCTGAAG
TTTTTTTTACCACCATCCTTTTCTACTCTGTATGGAAGTAGATCTTTATGGGGAAAAGAGAATT
TGGGGTGTTCTGCAAGCTAGTCAAAGTGGCACAGCAAATCATATAAATCGAATTAAATGGACAA
CACCGTTAGATGTGTATGTAAAAATTTTGTTTCATATTTTTCCTTTCACTTTCGGTTTAAAACA
TGCTATATGTACTGTATGTCCTGTAGCCCAGTGCAGCTCCACAGCATGGAATCTGATGTATGAT
ATGATAGAATGTGGCACTAAATGCAGTTTCAGATTTTATTTTTTTTAATGATATGAACTAAAAT
TGTCAATTGTGAGGTGTGCTTTTCTCATCATGTTGGTTATATTGCACAATTGGTTATATTTATG
ACCTGATATTCAAAGACTCTGGCATTGATAGCCAGTGTGTTTTCTTATTTAATTCCATTTACTA
CATTCTACATGGTGTTTACGTGATCCACACTTGAAATACTAGATCAGTAGACATTCACTAATAT
ACCAAAATAAAATGAAAAATGGAGTTTTTCCGTGAACTTTATACTGTCCAGCTCTGTTGATTTT
AAAGCCTCTTCATCCAGGTCAGTTCAGGAAGTATATCTGGAGTACCTGCTCTGTTTTTGGCTGT
GAGACTAGCACTAAGGATTCTGGTACCTTTACCCAAACCTACTGGGCTACTAATACTTCTCTCA
GCAGTTGATCAAATACAATAGACCATGTAAGCTGGGGCCGCTCATCCACTTCCAGTTTGCTGGT
CTCCCTGCTAGAAAACACATTGTACTGTGCTTTTTCTGGAATTCAGTATAATGGCATCACTGCC
TGTTTTTCACACCTTTGGTTTCCTGTTCATTTTAAGGAAACCTACTAAATCCAGTTAATATTAA
ATGGACACCACTCATTAAGAAATTTCTTTATGGCTTCTGCTGAATACTTAAATGCCTTACTACA
GTTATCCAGTTGACATGTTTTTAATTCATATAAGGTATATTGGGTATATTGAAGTATATATTGT
ATTACAAAGACTTGTTCTTGTATTTTAAAATGTCAGTGCAAAAAATATATGGTGGAACCTTTCT
TTAAAGTTGAAATGCAGTATTATTTAAATCTGAAAGGTTAAAAAGCTTTCTTCACCTTATATAT
GTTCTTCCACTGTGACTTTGTAGTTGAAGACTAGTAAATTAACTTTTAGTTAGAAGATGCCTAC
TGCTTTTGTTGTTTATTTTAGTCAGCAGAGCACAGAGACACATAAAAACTCTGGGAAATGACTG
GGATAAAAATATCAGTATGTATCTGTTTTAGATATTTTGAGTTTTGCTTTTTTTATGCCTTGAA
TATTTTATTTCAAAAAGTATCTGAAGCAAATTCTCAGACTGAACTACTTCTTAGACCTCACTGT
AAGAATGTTTTATTCAATGTCTCATTTATGATAGATTTGCAAGCTGCTCATTTTTGAACAGCTT
TTTGCATGGGATAGGAGCATGTCTATTCTAACACATCAGCTTATTCAAAAGCAAGAATTTTGAA
AATAAGATAAATGTAAAGTTGTTTTATAAACGATCCTGTTAATTAAACCACAGACACCATATAT
CCTTCTGCATCCTTTGGCCAATAAAAGTTGCTGGAGAACCAAA

hide sequence

RefSeq Acc Id:

XM_034948632 ⟹ XP_034804523

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	19,908,609 - 19,942,403 (-)	NCBI
NHGRI_mPanPan1	1	20,100,875 - 20,130,339 (-)	NCBI
Mhudiblu_PPA_v0	1	204,818,472 - 204,847,952 (+)	NCBI

RefSeq Acc Id:

XM_034948636 ⟹ XP_034804527

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	19,907,239 - 19,923,581 (-)	NCBI
NHGRI_mPanPan1	1	20,099,505 - 20,112,456 (-)	NCBI
Mhudiblu_PPA_v0	1	204,836,388 - 204,849,775 (+)	NCBI

RefSeq Acc Id:

XM_055104111 ⟹ XP_054960086

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	19,907,239 - 19,927,089 (-)	NCBI
NHGRI_mPanPan1	1	20,099,505 - 20,115,028 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_003824504	(Get FASTA)	NCBI Sequence Viewer
	XP_008976412	(Get FASTA)	NCBI Sequence Viewer
	XP_034804523	(Get FASTA)	NCBI Sequence Viewer
	XP_034804527	(Get FASTA)	NCBI Sequence Viewer
	XP_054960086	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000027074
	ENSPPAP00000027074.1
	ENSPPAP00000027087.1
	ENSPPAP00000027094.1

RefSeq Acc Id:	XP_003824504 ⟸ XM_003824456
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9BBV5 (UniProtKB/TrEMBL), A0A2R9BBX2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSQTAMSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKL QIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKK DLDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGI QYGDAALRQLRSPRRAQAPNAQECGC hide sequence

RefSeq Acc Id:	XP_008976412 ⟸ XM_008978164
- Peptide Label:	isoform X2
- Sequence:	show sequence MISPDARMLASQNIVIILCGNKKDLDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQ CARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRAQAPNAQECGC hide sequence

RefSeq Acc Id:	XP_034804523 ⟸ XM_034948632
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9BBV5 (UniProtKB/TrEMBL), A0A2R9BBX2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034804527 ⟸ XM_034948636
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSPPAP00000027094 ⟸ ENSPPAT00000049930

Ensembl Acc Id:

ENSPPAP00000027074 ⟸ ENSPPAT00000049910

Ensembl Acc Id:

ENSPPAP00000027087 ⟸ ENSPPAT00000049923

RefSeq Acc Id:	XP_054960086 ⟸ XM_055104111
- Peptide Label:	isoform X2

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000036595	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000049910.1	UniProtKB/TrEMBL
	ENSPPAT00000049923.1	UniProtKB/TrEMBL
	ENSPPAT00000049930.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	P-loop_NTPase	UniProtKB/TrEMBL
	Rab4	UniProtKB/TrEMBL
	Rab_GTPases_membrane_traffic	UniProtKB/TrEMBL
	Small_GTP-bd_dom	UniProtKB/TrEMBL
	Small_GTPase	UniProtKB/TrEMBL
KEGG Report	pps:100986270	UniProtKB/TrEMBL
NCBI Gene	RAB4A	ENTREZGENE
PANTHER	DRAB11-RELATED	UniProtKB/TrEMBL
	RAS-RELATED PROTEIN RAB-4A	UniProtKB/TrEMBL
Pfam	Ras	UniProtKB/TrEMBL
PRINTS	RASTRNSFRMNG	UniProtKB/TrEMBL
PROSITE	RAB	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
SMART	ARF	UniProtKB/TrEMBL
	RAB	UniProtKB/TrEMBL
	RAN	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A2R9BBV5	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9BBX2	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9BD59_PANPA	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-06-11	RAB4A	RAB4A, member RAS oncogene family	SPHAR	S-phase response (cyclin related)	Data merged from RGD:11837326	737654	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - PID (archival)