ARHGAP40 (Rho GTPase activating protein 40) - Rat Genome Database

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Gene: ARHGAP40 (Rho GTPase activating protein 40) Pan paniscus
Analyze
Symbol: ARHGAP40
Name: Rho GTPase activating protein 40
RGD ID: 11856286
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of actin filament polymerization (inferred); regulation of small GTPase mediated signal transduction (inferred); signal transduction (inferred); ASSOCIATED WITH focal epilepsy (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: rho GTPase-activating protein 40
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22144,327,071 - 44,375,987 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12044,320,169 - 44,369,085 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02034,926,329 - 34,975,079 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12036,034,643 - 36,083,390 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2036,034,643 - 36,083,390 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ARHGAP40
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22144,327,071 - 44,375,987 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12044,320,169 - 44,369,085 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02034,926,329 - 34,975,079 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12036,034,643 - 36,083,390 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2036,034,643 - 36,083,390 (+)Ensemblpanpan1.1panPan2
ARHGAP40
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382038,601,809 - 38,650,653 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2038,601,809 - 38,651,035 (+)EnsemblGRCh38hg38GRCh38
GRCh372037,230,452 - 37,279,296 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362036,685,438 - 36,762,920 (+)NCBINCBI36Build 36hg18NCBI36
Celera2033,941,365 - 33,990,115 (+)NCBICelera
Cytogenetic Map20q11.23NCBI
HuRef2033,967,419 - 34,016,092 (+)NCBIHuRef
CHM1_12037,134,779 - 37,183,507 (+)NCBICHM1_1
T2T-CHM13v2.02040,331,453 - 40,380,311 (+)NCBIT2T-CHM13v2.0
Arhgap40
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392158,354,682 - 158,392,786 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2158,354,716 - 158,392,682 (+)EnsemblGRCm39 Ensembl
GRCm382158,512,796 - 158,550,628 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2158,512,796 - 158,550,762 (+)EnsemblGRCm38mm10GRCm38
MGSCv372158,338,532 - 158,376,364 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362158,204,237 - 158,242,069 (+)NCBIMGSCv36mm8
Celera2164,435,056 - 164,483,561 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map278.72NCBI
Arhgap40
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83167,585,665 - 167,626,433 (+)NCBIGRCr8
mRatBN7.23147,165,781 - 147,206,552 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3147,165,729 - 147,207,203 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3150,998,123 - 151,038,744 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03159,497,426 - 159,538,053 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03157,232,799 - 157,273,462 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03154,996,685 - 155,042,199 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3154,996,750 - 155,041,816 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03160,564,782 - 160,610,205 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43149,229,094 - 149,277,444 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3145,866,334 - 145,905,540 (+)NCBICelera
Cytogenetic Map3q42NCBI
Arhgap40
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495544518,099,490 - 18,121,225 (-)NCBIChiLan1.0ChiLan1.0
ARHGAP40
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12427,047,119 - 27,074,211 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2426,692,596 - 26,719,660 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02427,743,317 - 27,770,450 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12427,017,025 - 27,044,131 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02427,125,357 - 27,152,492 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02427,613,396 - 27,640,501 (+)NCBIUU_Cfam_GSD_1.0
ARHGAP40
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1225,105,788 - 25,161,502 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl225,106,573 - 25,134,690 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605073,935,656 - 73,997,371 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000047618   ⟹   ENSPPAP00000024793
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2036,034,643 - 36,083,390 (+)Ensembl
RefSeq Acc Id: XM_008951272   ⟹   XP_008949520
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22144,327,071 - 44,375,987 (+)NCBI
NHGRI_mPanPan12044,320,175 - 44,369,085 (+)NCBI
Mhudiblu_PPA_v02034,926,329 - 34,975,079 (+)NCBI
PanPan1.12036,034,643 - 36,083,390 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055104483   ⟹   XP_054960458
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22144,327,077 - 44,375,987 (+)NCBI
NHGRI_mPanPan12044,320,175 - 44,369,085 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008949520 (Get FASTA)   NCBI Sequence Viewer  
  XP_054960458 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000024793.1
Reference Protein Sequences
RefSeq Acc Id: XP_008949520   ⟸   XM_008951272
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B5D1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000024793   ⟸   ENSPPAT00000047618
RefSeq Acc Id: XP_054960458   ⟸   XM_055104483
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B5D1 (UniProtKB/TrEMBL)
Protein Domains
Rho-GAP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035531 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000047618.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/TrEMBL
InterPro Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
NCBI Gene ARHGAP40 ENTREZGENE
PANTHER RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED UniProtKB/TrEMBL
  RHO GTPASE-ACTIVATING PROTEIN 40 UniProtKB/TrEMBL
Pfam RhoGAP UniProtKB/TrEMBL
PROSITE RHOGAP UniProtKB/TrEMBL
SMART RhoGAP UniProtKB/TrEMBL
Superfamily-SCOP SSF48350 UniProtKB/TrEMBL
UniProt A0A2R9B5D1 ENTREZGENE, UniProtKB/TrEMBL