PSD3 (pleckstrin and Sec7 domain containing 3) - Rat Genome Database

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Gene: PSD3 (pleckstrin and Sec7 domain containing 3) Pan paniscus
Analyze
Symbol: PSD3
Name: pleckstrin and Sec7 domain containing 3
RGD ID: 11957930
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); phospholipid binding (inferred); INVOLVED IN regulation of ARF protein signal transduction (inferred); ASSOCIATED WITH amphetamine abuse (ortholog); Contracture (ortholog); genetic disease (ortholog); FOUND IN cleavage furrow (ortholog); glutamatergic synapse (ortholog); membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC103786969; PH and SEC7 domain-containing protein 3; uncharacterized LOC103786969
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2737,011,500 - 37,725,363 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1812,736,722 - 13,464,979 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0817,758,287 - 18,308,876 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1814,706,850 - 15,259,170 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl814,714,575 - 15,258,823 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PSD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2737,011,500 - 37,725,363 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1812,736,722 - 13,464,979 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0817,758,287 - 18,308,876 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1814,706,850 - 15,259,170 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl814,714,575 - 15,258,823 (-)Ensemblpanpan1.1panPan2
PSD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38818,527,303 - 19,084,805 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl818,527,303 - 19,084,730 (-)EnsemblGRCh38hg38GRCh38
GRCh37818,384,813 - 18,871,213 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36818,429,093 - 18,915,476 (-)NCBINCBI36Build 36hg18NCBI36
Celera817,351,147 - 17,835,744 (-)NCBICelera
Cytogenetic Map8p22NCBI
HuRef816,929,317 - 17,412,683 (-)NCBIHuRef
CHM1_1818,586,292 - 19,072,714 (-)NCBICHM1_1
T2T-CHM13v2.0818,794,850 - 19,349,609 (-)NCBIT2T-CHM13v2.0
Psd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39868,141,728 - 68,664,740 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl868,141,734 - 68,664,679 (-)EnsemblGRCm39 Ensembl
GRCm38867,689,082 - 68,212,063 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl867,689,082 - 68,212,027 (-)EnsemblGRCm38mm10GRCm38
MGSCv37870,212,981 - 70,498,473 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36870,625,036 - 70,903,563 (-)NCBIMGSCv36mm8
Celera870,232,989 - 70,519,004 (-)NCBICelera
Cytogenetic Map8B3.2- B3.3NCBI
cM Map833.46NCBI
Psd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81626,238,595 - 26,802,535 (+)NCBIGRCr8
mRatBN7.21621,465,643 - 22,035,846 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1621,465,639 - 22,034,547 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01623,212,165 - 23,789,414 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1623,447,366 - 23,781,604 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01623,099,943 - 23,673,970 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41623,194,137 - 23,662,010 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1621,624,379 - 22,176,442 (+)NCBICelera
Cytogenetic Map16p14NCBI
Psd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540342,451,485 - 42,932,948 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540342,442,708 - 42,943,314 (-)NCBIChiLan1.0ChiLan1.0
PSD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11621,328,491 - 21,921,378 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1621,336,642 - 21,921,460 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1621,835,321 - 22,427,295 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01623,062,751 - 23,661,573 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1623,062,752 - 23,661,465 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11621,428,758 - 21,945,684 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01622,014,238 - 22,733,274 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01622,064,528 - 22,658,581 (-)NCBIUU_Cfam_GSD_1.0
Psd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494315,250,693 - 15,615,297 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365552,963,963 - 3,284,619 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365552,955,982 - 3,253,064 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PSD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1712,758,536 - 13,264,174 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11712,645,743 - 13,267,176 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21713,573,794 - 14,045,089 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PSD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1816,623,640 - 17,171,820 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl816,628,787 - 17,098,824 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605225,081,275 - 25,637,066 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Psd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475814,483,447 - 14,793,268 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475814,474,626 - 14,965,281 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003823634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003823635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008977296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034965713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034965714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055116331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055116335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055116339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055116340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055116341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_057302980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_057302981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_057302982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063607125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063607126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063607127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000029171   ⟹   ENSPPAP00000007112
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl814,714,575 - 15,258,823 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000029175   ⟹   ENSPPAP00000007116
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl814,715,303 - 14,861,860 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000029186   ⟹   ENSPPAP00000007119
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl814,975,955 - 14,985,473 (-)Ensembl
RefSeq Acc Id: XM_003823634   ⟹   XP_003823682
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2737,011,500 - 37,725,363 (-)NCBI
NHGRI_mPanPan1812,736,722 - 13,451,033 (-)NCBI
Mhudiblu_PPA_v0817,758,308 - 18,308,876 (-)NCBI
PanPan1.1814,706,850 - 15,259,170 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003823635   ⟹   XP_003823683
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2737,011,500 - 37,291,173 (-)NCBI
NHGRI_mPanPan1812,736,722 - 13,016,404 (-)NCBI
Mhudiblu_PPA_v0817,758,287 - 18,034,443 (-)NCBI
PanPan1.1814,706,850 - 14,985,582 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008977296   ⟹   XP_008975544
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2737,011,500 - 37,368,817 (-)NCBI
NHGRI_mPanPan1812,736,722 - 13,094,443 (-)NCBI
Mhudiblu_PPA_v0817,758,287 - 18,114,308 (-)NCBI
PanPan1.1814,710,412 - 15,063,421 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034965713   ⟹   XP_034821604
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2737,011,500 - 37,495,029 (-)NCBI
NHGRI_mPanPan1812,736,722 - 13,220,319 (-)NCBI
Mhudiblu_PPA_v0817,758,287 - 18,238,342 (-)NCBI
RefSeq Acc Id: XM_034965714   ⟹   XP_034821605
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2737,011,500 - 37,369,143 (-)NCBI
NHGRI_mPanPan1812,736,722 - 13,094,446 (-)NCBI
Mhudiblu_PPA_v0817,758,308 - 18,114,307 (-)NCBI
RefSeq Acc Id: XM_055116331   ⟹   XP_054972306
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2737,011,500 - 37,725,363 (-)NCBI
NHGRI_mPanPan1812,736,722 - 13,451,033 (-)NCBI
RefSeq Acc Id: XM_055116335   ⟹   XP_054972310
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2737,253,056 - 37,725,363 (-)NCBI
NHGRI_mPanPan1812,978,115 - 13,451,033 (-)NCBI
RefSeq Acc Id: XM_055116339   ⟹   XP_054972314
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2737,011,500 - 37,336,524 (-)NCBI
NHGRI_mPanPan1812,736,722 - 13,061,812 (-)NCBI
RefSeq Acc Id: XM_055116340   ⟹   XP_054972315
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2737,011,500 - 37,166,782 (-)NCBI
NHGRI_mPanPan1812,736,722 - 12,892,040 (-)NCBI
RefSeq Acc Id: XM_055116341   ⟹   XP_054972316
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2737,226,784 - 37,291,013 (-)NCBI
NHGRI_mPanPan1812,960,879 - 13,020,515 (-)NCBI
RefSeq Acc Id: XM_057302980   ⟹   XP_057158963
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2737,226,784 - 37,495,029 (-)NCBI
NHGRI_mPanPan1812,960,882 - 13,220,273 (-)NCBI
RefSeq Acc Id: XM_057302981   ⟹   XP_057158964
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2737,253,056 - 37,494,953 (-)NCBI
NHGRI_mPanPan1812,978,115 - 13,220,273 (-)NCBI
RefSeq Acc Id: XM_057302982   ⟹   XP_057158965
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2737,245,314 - 37,291,013 (-)NCBI
NHGRI_mPanPan1812,970,594 - 13,020,515 (-)NCBI
RefSeq Acc Id: XM_063607125   ⟹   XP_063463195
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2737,011,500 - 37,715,838 (-)NCBI
RefSeq Acc Id: XM_063607126   ⟹   XP_063463196
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2737,011,500 - 37,715,838 (-)NCBI
RefSeq Acc Id: XM_063607127   ⟹   XP_063463197
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2737,011,500 - 37,421,368 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003823682   ⟸   XM_003823634
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_003823683   ⟸   XM_003823635
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_008975544   ⟸   XM_008977296
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_034821604   ⟸   XM_034965713
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034821605   ⟸   XM_034965714
- Peptide Label: isoform X4
RefSeq Acc Id: ENSPPAP00000007119   ⟸   ENSPPAT00000029186
RefSeq Acc Id: ENSPPAP00000007112   ⟸   ENSPPAT00000029171
RefSeq Acc Id: ENSPPAP00000007116   ⟸   ENSPPAT00000029175
RefSeq Acc Id: XP_054972306   ⟸   XM_055116331
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054972314   ⟸   XM_055116339
- Peptide Label: isoform X9
RefSeq Acc Id: XP_054972315   ⟸   XM_055116340
- Peptide Label: isoform X10
- UniProtKB: A0A2R8ZQA0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054972316   ⟸   XM_055116341
- Peptide Label: isoform X11
RefSeq Acc Id: XP_054972310   ⟸   XM_055116335
- Peptide Label: isoform X5
RefSeq Acc Id: XP_057158963   ⟸   XM_057302980
- Peptide Label: isoform X6
RefSeq Acc Id: XP_057158965   ⟸   XM_057302982
- Peptide Label: isoform X14
RefSeq Acc Id: XP_057158964   ⟸   XM_057302981
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063463195   ⟸   XM_063607125
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063463196   ⟸   XM_063607126
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063463197   ⟸   XM_063607127
- Peptide Label: isoform X13
Protein Domains
PH   SEC7


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000026209 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000029171.1 UniProtKB/TrEMBL
  ENSPPAT00000029175.1 UniProtKB/TrEMBL
  ENSPPAT00000029186.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1000.11 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  PH_9 UniProtKB/TrEMBL
  PH_dom-spectrin-type UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  Sec7_C_sf UniProtKB/TrEMBL
  Sec7_dom UniProtKB/TrEMBL
  Sec7_dom_sf UniProtKB/TrEMBL
NCBI Gene PSD3 ENTREZGENE
PANTHER GUANYL-NUCLEOTIDE EXCHANGE FACTOR UniProtKB/TrEMBL
  PH AND SEC7 DOMAIN-CONTAINING PROTEIN 3 UniProtKB/TrEMBL
Pfam PH_9 UniProtKB/TrEMBL
  Sec7 UniProtKB/TrEMBL
PRINTS SPECTRINPH UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  SEC7 UniProtKB/TrEMBL
SMART Sec7 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF48425 UniProtKB/TrEMBL
UniProt A0A2R8ZQA0 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZRF8_PANPA UniProtKB/TrEMBL
  A0A2R8ZW47_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-04-20 PSD3  pleckstrin and Sec7 domain containing 3  LOC103786969  uncharacterized LOC103786969  Data merged from RGD:11856205 737654 PROVISIONAL