NKIRAS2 (NFKB inhibitor interacting Ras like 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: NKIRAS2 (NFKB inhibitor interacting Ras like 2) Pan paniscus
Analyze
Symbol: NKIRAS2
Name: NFKB inhibitor interacting Ras like 2
RGD ID: 11805479
Description: ENCODES a protein that exhibits GTP binding (inferred); GTPase activating protein binding (inferred); GTPase activity (inferred); INVOLVED IN inflammatory response (ortholog); lung alveolus development (ortholog); Ral protein signal transduction (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NF-kappa-B inhibitor-interacting Ras-like protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21922,958,507 - 22,966,693 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11724,848,008 - 24,856,811 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01715,290,435 - 15,299,060 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11715,509,753 - 15,518,379 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1715,509,758 - 15,518,379 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NKIRAS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21922,958,507 - 22,966,693 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11724,848,008 - 24,856,811 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01715,290,435 - 15,299,060 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11715,509,753 - 15,518,379 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1715,509,758 - 15,518,379 (-)Ensemblpanpan1.1panPan2
NKIRAS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381742,017,576 - 42,025,641 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1742,011,382 - 42,025,644 (+)EnsemblGRCh38hg38GRCh38
GRCh371740,169,594 - 40,177,659 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361737,422,564 - 37,431,185 (+)NCBINCBI36Build 36hg18NCBI36
Build 341737,425,617 - 37,431,180NCBI
Celera1736,824,646 - 36,832,710 (+)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1735,934,823 - 35,942,887 (+)NCBIHuRef
CHM1_11740,405,335 - 40,413,399 (+)NCBICHM1_1
T2T-CHM13v2.01742,874,107 - 42,882,171 (+)NCBIT2T-CHM13v2.0
Nkiras2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911100,510,007 - 100,518,436 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11100,510,070 - 100,518,433 (+)EnsemblGRCm39 Ensembl
GRCm3811100,619,181 - 100,627,610 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11100,619,244 - 100,627,607 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711100,484,269 - 100,488,916 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611100,439,045 - 100,443,692 (+)NCBIMGSCv36mm8
Celera11111,243,278 - 111,247,925 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1163.47NCBI
Nkiras2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81086,055,029 - 86,062,398 (+)NCBIGRCr8
mRatBN7.21085,554,704 - 85,562,072 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1085,557,944 - 85,562,072 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1090,594,691 - 90,598,718 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01090,073,210 - 90,077,237 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01085,466,283 - 85,470,310 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01088,536,564 - 88,540,739 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1088,536,626 - 88,540,733 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01088,327,831 - 88,335,063 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41089,567,630 - 89,571,657 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11089,581,876 - 89,586,033 (+)NCBI
Celera1084,274,269 - 84,278,296 (+)NCBICelera
Cytogenetic Map10q31NCBI
Nkiras2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545116,147,599 - 16,151,090 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545116,147,598 - 16,151,090 (+)NCBIChiLan1.0ChiLan1.0
NKIRAS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1920,851,014 - 20,854,953 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl920,852,103 - 20,854,892 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha920,311,701 - 20,315,870 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0921,569,552 - 21,573,718 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl921,569,486 - 21,573,658 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1920,354,795 - 20,358,963 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0920,621,894 - 20,626,059 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0920,725,019 - 20,729,187 (-)NCBIUU_Cfam_GSD_1.0
Nkiras2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560220,188,297 - 20,191,779 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493649016,883,418 - 16,886,835 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NKIRAS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1220,717,547 - 20,723,704 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11220,717,545 - 20,723,141 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21221,007,683 - 21,013,083 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NKIRAS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11664,236,581 - 64,242,535 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1664,238,347 - 64,242,521 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607735,053,958 - 35,059,918 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nkiras2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247951,828,046 - 1,830,483 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247951,828,046 - 1,830,880 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000019457   ⟹   ENSPPAP00000004184
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1715,509,758 - 15,518,379 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000019476   ⟹   ENSPPAP00000004191
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1715,509,758 - 15,515,324 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000019510   ⟹   ENSPPAP00000004200
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1715,511,504 - 15,513,816 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000019519   ⟹   ENSPPAP00000004205
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1715,511,689 - 15,515,317 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000019541   ⟹   ENSPPAP00000004209
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1715,511,712 - 15,513,816 (-)Ensembl
RefSeq Acc Id: XM_003813861   ⟹   XP_003813909
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21922,958,507 - 22,964,081 (-)NCBI
NHGRI_mPanPan11724,848,656 - 24,854,326 (-)NCBI
Mhudiblu_PPA_v01715,290,435 - 15,296,025 (-)NCBI
PanPan1.11715,509,753 - 15,515,342 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003813862   ⟹   XP_003813910
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21922,958,507 - 22,966,693 (-)NCBI
NHGRI_mPanPan11724,848,654 - 24,856,811 (-)NCBI
Mhudiblu_PPA_v01715,290,435 - 15,299,060 (-)NCBI
PanPan1.11715,509,753 - 15,518,379 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003813864   ⟹   XP_003813912
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21922,958,507 - 22,964,082 (-)NCBI
NHGRI_mPanPan11724,848,654 - 24,854,210 (-)NCBI
Mhudiblu_PPA_v01715,290,435 - 15,295,985 (-)NCBI
PanPan1.11715,509,753 - 15,515,304 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003813865   ⟹   XP_003813913
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21922,958,507 - 22,964,081 (-)NCBI
NHGRI_mPanPan11724,848,008 - 24,854,230 (-)NCBI
Mhudiblu_PPA_v01715,290,435 - 15,296,026 (-)NCBI
PanPan1.11715,509,753 - 15,515,324 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034941869   ⟹   XP_034797760
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21922,958,507 - 22,964,095 (-)NCBI
NHGRI_mPanPan11724,848,016 - 24,854,244 (-)NCBI
Mhudiblu_PPA_v01715,290,435 - 15,296,021 (-)NCBI
RefSeq Acc Id: XM_063599045   ⟹   XP_063455115
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21922,958,507 - 22,966,661 (-)NCBI
RefSeq Acc Id: XP_003813910   ⟸   XM_003813862
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZGS1 (UniProtKB/TrEMBL),   A0A2R8ZGT8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003813909   ⟸   XM_003813861
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZGS1 (UniProtKB/TrEMBL),   A0A2R8ZGT8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003813913   ⟸   XM_003813865
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZHD1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003813912   ⟸   XM_003813864
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZGS1 (UniProtKB/TrEMBL),   A0A2R8ZGT8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034797760   ⟸   XM_034941869
- Peptide Label: isoform X3
Ensembl Acc Id: ENSPPAP00000004191   ⟸   ENSPPAT00000019476
Ensembl Acc Id: ENSPPAP00000004184   ⟸   ENSPPAT00000019457
Ensembl Acc Id: ENSPPAP00000004200   ⟸   ENSPPAT00000019510
Ensembl Acc Id: ENSPPAP00000004205   ⟸   ENSPPAT00000019519
Ensembl Acc Id: ENSPPAP00000004209   ⟸   ENSPPAT00000019541
RefSeq Acc Id: XP_063455115   ⟸   XM_063599045
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZHD1 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000017742 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000019457.1 UniProtKB/TrEMBL
  ENSPPAT00000019476.1 UniProtKB/TrEMBL
  ENSPPAT00000019510.1 UniProtKB/TrEMBL
  ENSPPAT00000019519.1 UniProtKB/TrEMBL
  ENSPPAT00000019541.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro KBRS UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
KEGG Report pps:100983060 UniProtKB/TrEMBL
NCBI Gene NKIRAS2 ENTREZGENE
PANTHER NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN 2 UniProtKB/TrEMBL
  PTHR46152 UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A2R8ZGS1 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZGT8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZGU2_PANPA UniProtKB/TrEMBL
  A0A2R8ZGU9_PANPA UniProtKB/TrEMBL
  A0A2R8ZHD1 ENTREZGENE, UniProtKB/TrEMBL