BCR (BCR activator of RhoGEF and GTPase) - Rat Genome Database

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Gene: BCR (BCR activator of RhoGEF and GTPase) Pan paniscus
Analyze
Symbol: BCR
Name: BCR activator of RhoGEF and GTPase
RGD ID: 11859825
Description: ENCODES a protein that exhibits enzyme binding (ortholog); GTPase activator activity (ortholog); guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); brain development (ortholog); cell migration (ortholog); ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); B-lymphoblastic leukemia/lymphoma (ortholog); Blast Crisis (ortholog); FOUND IN cytosol (ortholog); glutamatergic synapse (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: active breakpoint cluster region-related protein-like; LOC106634246
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22333,011,678 - 33,149,165 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12234,933,439 - 35,070,914 (-)NCBINHGRI_mPanPan1
PanPan1.12221,803,806 - 21,922,123 (+)NCBIpanpan1.1PanPan1.1panPan2


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
BCR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22333,011,678 - 33,149,165 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12234,933,439 - 35,070,914 (-)NCBINHGRI_mPanPan1
PanPan1.12221,803,806 - 21,922,123 (+)NCBIpanpan1.1PanPan1.1panPan2
BCR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382223,180,509 - 23,318,037 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2223,179,704 - 23,318,037 (+)EnsemblGRCh38hg38GRCh38
GRCh372223,522,696 - 23,660,224 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362221,852,552 - 21,990,224 (+)NCBINCBI36Build 36hg18NCBI36
Build 342221,847,105 - 21,982,690NCBI
Celera227,337,083 - 7,474,738 (+)NCBICelera
Cytogenetic Map22q11.23ENTREZGENE
HuRef226,461,675 - 6,627,574 (+)NCBIHuRef
CHM1_12223,534,806 - 23,672,427 (+)NCBICHM1_1
T2T-CHM13v2.02223,603,367 - 23,740,899 (+)NCBIT2T-CHM13v2.0
Bcr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391074,896,384 - 75,020,753 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1074,896,424 - 75,020,753 (+)EnsemblGRCm39 Ensembl
GRCm381075,060,560 - 75,184,923 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1075,060,592 - 75,184,921 (+)EnsemblGRCm38mm10GRCm38
MGSCv371074,523,641 - 74,647,668 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361074,504,612 - 74,628,764 (+)NCBIMGSCv36mm8
MGSCv361075,455,937 - 75,580,316 (+)NCBIMGSCv36mm8
Celera1076,108,779 - 76,233,250 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1038.49NCBI
Bcr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82013,468,732 - 13,596,333 (-)NCBIGRCr8
mRatBN7.22013,469,325 - 13,596,942 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2013,471,668 - 13,597,016 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.02014,421,250 - 14,546,406 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2014,421,141 - 14,545,772 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02016,604,476 - 16,729,388 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42013,972,773 - 14,097,816 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12013,973,364 - 14,098,043 (-)NCBI
Celera2014,955,473 - 15,079,934 (-)NCBICelera
Cytogenetic Map20p12NCBI
Bcr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554557,598,794 - 7,727,386 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554557,598,794 - 7,727,386 (+)NCBIChiLan1.0ChiLan1.0
BCR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12627,856,280 - 27,980,923 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2627,856,082 - 27,978,318 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2626,931,961 - 27,056,311 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02629,260,365 - 29,385,328 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12627,343,693 - 27,468,548 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02626,961,155 - 27,085,857 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02627,950,465 - 28,075,113 (+)NCBIUU_Cfam_GSD_1.0
Bcr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118142,324,235 - 142,465,697 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936619288,340 - 432,315 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936619288,377 - 432,297 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BCR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1449,208,762 - 49,322,103 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11449,208,662 - 49,322,109 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21452,727,404 - 52,771,825 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BCR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1192,569,841 - 2,703,703 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl192,566,190 - 2,702,920 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660854,423,712 - 4,553,443 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bcr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247479,528,996 - 9,662,131 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247479,528,968 - 9,664,055 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_034951698   ⟹   XP_034807589
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22333,012,070 - 33,149,165 (+)NCBI
NHGRI_mPanPan12234,933,439 - 35,070,525 (-)NCBI
RefSeq Acc Id: XM_034951699   ⟹   XP_034807590
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22333,011,678 - 33,149,165 (+)NCBI
NHGRI_mPanPan12234,933,439 - 35,070,914 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034807589 (Get FASTA)   NCBI Sequence Viewer  
  XP_034807590 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_034807589   ⟸   XM_034951698
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034807590   ⟸   XM_034951699
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
NCBI Gene BCR ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-06-11 BCR  BCR activator of RhoGEF and GTPase  LOC106634246  active breakpoint cluster region-related protein-like  Data merged from RGD:11722662 737654 PROVISIONAL
2019-01-29 BCR  BCR activator of RhoGEF and GTPase    BCR, RhoGEF and GTPase activating protein  Symbol and/or name change 5135510 APPROVED