RACGAP1 (Rac GTPase activating protein 1) - Rat Genome Database

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Gene: RACGAP1 (Rac GTPase activating protein 1) Pan paniscus
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Symbol: RACGAP1
Name: Rac GTPase activating protein 1
RGD ID: 11965473
Description: ENCODES a protein that exhibits alpha-tubulin binding (inferred); beta-tubulin binding (inferred); gamma-tubulin binding (inferred); INVOLVED IN neuroblast proliferation (ortholog); regulation of embryonic development (ortholog); ASSOCIATED WITH Congenital Dyserythropoietic Anemia Type IIIb (ortholog); hepatocellular carcinoma (ortholog); polycystic ovary syndrome (ortholog); FOUND IN mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: rac GTPase-activating protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21044,163,317 - 44,199,581 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11244,160,108 - 44,196,343 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01238,729,885 - 38,766,063 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11239,625,763 - 39,660,040 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1239,625,796 - 39,672,256 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
RACGAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21044,163,317 - 44,199,581 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11244,160,108 - 44,196,343 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01238,729,885 - 38,766,063 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11239,625,763 - 39,660,040 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1239,625,796 - 39,672,256 (+)Ensemblpanpan1.1panPan2
RACGAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381249,989,162 - 50,033,440 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1249,976,923 - 50,033,136 (-)EnsemblGRCh38hg38GRCh38
GRCh371250,382,945 - 50,419,277 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361248,669,212 - 48,705,488 (-)NCBINCBI36Build 36hg18NCBI36
Build 341248,669,211 - 48,705,488NCBI
Celera1249,179,065 - 49,215,304 (-)NCBICelera
Cytogenetic Map12q13.12NCBI
HuRef1247,414,446 - 47,451,548 (-)NCBIHuRef
CHM1_11250,349,102 - 50,385,463 (-)NCBICHM1_1
T2T-CHM13v2.01249,952,172 - 49,996,504 (-)NCBIT2T-CHM13v2.0
Racgap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391599,518,377 - 99,549,504 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1599,518,377 - 99,549,537 (-)EnsemblGRCm39 Ensembl
GRCm381599,620,496 - 99,651,656 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1599,620,496 - 99,651,656 (-)EnsemblGRCm38mm10GRCm38
MGSCv371599,450,927 - 99,482,052 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361599,448,530 - 99,479,655 (-)NCBIMGSCv36mm8
Celera15101,775,878 - 101,807,252 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.13NCBI
Racgap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87132,629,789 - 132,659,738 (-)NCBIGRCr8
mRatBN7.27130,750,936 - 130,780,891 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7130,750,936 - 130,780,831 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7132,555,040 - 132,584,440 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07134,780,620 - 134,810,026 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07134,693,146 - 134,722,541 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07141,277,303 - 141,308,849 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7141,277,312 - 141,307,233 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07138,713,215 - 138,728,271 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47138,366,356 - 138,395,716 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17138,443,204 - 138,463,026 (-)NCBI
Celera7127,232,693 - 127,262,334 (-)NCBICelera
Cytogenetic Map7q36NCBI
Racgap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955547581,134 - 616,087 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955547584,885 - 615,883 (-)NCBIChiLan1.0ChiLan1.0
RACGAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1274,689,914 - 4,718,181 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl274,689,483 - 4,727,933 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2741,541,242 - 41,569,279 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,737,980 - 4,766,051 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,738,129 - 4,775,802 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1274,702,991 - 4,731,034 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0274,692,808 - 4,720,859 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02741,935,897 - 41,964,171 (-)NCBIUU_Cfam_GSD_1.0
Racgap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494565,468,262 - 65,499,692 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365127,665,208 - 7,689,112 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365127,665,144 - 7,696,615 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RACGAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl515,904,712 - 15,943,609 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1515,894,314 - 15,943,619 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2516,400,485 - 16,403,961 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RACGAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11146,218,987 - 46,260,477 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1146,220,090 - 46,254,602 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037199,866,951 - 199,902,603 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Racgap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248162,273,856 - 2,303,375 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248162,268,879 - 2,303,305 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000063851   ⟹   ENSPPAP00000040930
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1239,625,796 - 39,660,040 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000063855   ⟹   ENSPPAP00000040934
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1239,656,876 - 39,672,256 (+)Ensembl
RefSeq Acc Id: XM_008951194   ⟹   XP_008949442
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21044,163,317 - 44,199,581 (+)NCBI
NHGRI_mPanPan11244,160,108 - 44,196,343 (+)NCBI
Mhudiblu_PPA_v01238,729,886 - 38,766,063 (+)NCBI
PanPan1.11239,625,763 - 39,660,040 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008951195   ⟹   XP_008949443
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21044,163,332 - 44,199,581 (+)NCBI
NHGRI_mPanPan11244,160,116 - 44,196,343 (+)NCBI
Mhudiblu_PPA_v01238,730,383 - 38,766,063 (+)NCBI
PanPan1.11239,625,842 - 39,660,040 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008951196   ⟹   XP_008949444
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21044,163,338 - 44,199,581 (+)NCBI
NHGRI_mPanPan11244,160,117 - 44,196,343 (+)NCBI
Mhudiblu_PPA_v01238,729,888 - 38,766,063 (+)NCBI
PanPan1.11239,625,763 - 39,660,040 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008951200   ⟹   XP_008949448
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21044,163,911 - 44,199,581 (+)NCBI
NHGRI_mPanPan11244,160,115 - 44,196,343 (+)NCBI
Mhudiblu_PPA_v01238,729,887 - 38,766,063 (+)NCBI
PanPan1.11239,625,763 - 39,660,040 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008951201   ⟹   XP_008949449
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21044,163,332 - 44,199,581 (+)NCBI
NHGRI_mPanPan11244,160,116 - 44,196,343 (+)NCBI
Mhudiblu_PPA_v01238,729,888 - 38,766,063 (+)NCBI
PanPan1.11239,625,763 - 39,660,040 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008951202   ⟹   XP_008949450
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21044,163,853 - 44,199,581 (+)NCBI
NHGRI_mPanPan11244,160,615 - 44,196,343 (+)NCBI
Mhudiblu_PPA_v01238,729,885 - 38,766,063 (+)NCBI
PanPan1.11239,625,763 - 39,660,040 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055095677   ⟹   XP_054951652
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21044,170,748 - 44,199,581 (+)NCBI
NHGRI_mPanPan11244,167,506 - 44,196,343 (+)NCBI
RefSeq Acc Id: XM_063593517   ⟹   XP_063449587
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21044,163,347 - 44,199,581 (+)NCBI
RefSeq Acc Id: XP_008949444   ⟸   XM_008951196
- Peptide Label: isoform X3
- UniProtKB: A0A2R9CG45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008949450   ⟸   XM_008951202
- Peptide Label: isoform X5
- UniProtKB: A0A2R9CG45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008949449   ⟸   XM_008951201
- Peptide Label: isoform X3
- UniProtKB: A0A2R9CG45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008949442   ⟸   XM_008951194
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CG45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008949448   ⟸   XM_008951200
- Peptide Label: isoform X3
- UniProtKB: A0A2R9CG45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008949443   ⟸   XM_008951195
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CG45 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000040934   ⟸   ENSPPAT00000063855
Ensembl Acc Id: ENSPPAP00000040930   ⟸   ENSPPAT00000063851
RefSeq Acc Id: XP_054951652   ⟸   XM_055095677
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063449587   ⟸   XM_063593517
- Peptide Label: isoform X4
Protein Domains
Phorbol-ester/DAG-type   Rho-GAP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043091 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000063851.1 UniProtKB/TrEMBL
  ENSPPAT00000063855.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/TrEMBL
InterPro C1-like_sf UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
NCBI Gene RACGAP1 ENTREZGENE
PANTHER RAC GTPASE-ACTIVATING PROTEIN 1 UniProtKB/TrEMBL
  RAC GTPASE-ACTIVATING PROTEIN 1 UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
PROSITE RHOGAP UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/TrEMBL
SMART RhoGAP UniProtKB/TrEMBL
  SM00109 UniProtKB/TrEMBL
Superfamily-SCOP SSF48350 UniProtKB/TrEMBL
  SSF57889 UniProtKB/TrEMBL
UniProt A0A2R9CG45 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CG93_PANPA UniProtKB/TrEMBL