RACGAP1 (Rac GTPase activating protein 1) - Rat Genome Database

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Gene: RACGAP1 (Rac GTPase activating protein 1) Homo sapiens
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Symbol: RACGAP1
Name: Rac GTPase activating protein 1
RGD ID: 1314228
HGNC Page HGNC:9804
Description: Enables several functions, including GTPase activator activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and tubulin binding activity. Involved in several processes, including cytoskeleton-dependent cytokinesis; mitotic spindle midzone assembly; and regulation of cell cycle process. Located in several cellular components, including cleavage furrow; midbody; and spindle. Part of centralspindlin complex. Implicated in congenital dyserythropoietic anemia type IIIb.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CDAN3B; CYK4; GTPase activating protein; HsCYK-4; ID-GAP; male germ cell RacGap; MgcRacGAP; protein CYK4 homolg; protein CYK4 homolog; rac GTPase-activating protein 1; RCGAP1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: RACGAP1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381249,989,162 - 50,033,440 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1249,976,923 - 50,033,136 (-)EnsemblGRCh38hg38GRCh38
GRCh371250,382,945 - 50,419,277 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361248,669,212 - 48,705,488 (-)NCBINCBI36Build 36hg18NCBI36
Build 341248,669,211 - 48,705,488NCBI
Celera1249,179,065 - 49,215,304 (-)NCBICelera
Cytogenetic Map12q13.12NCBI
HuRef1247,414,446 - 47,451,548 (-)NCBIHuRef
CHM1_11250,349,102 - 50,385,463 (-)NCBICHM1_1
T2T-CHM13v2.01249,952,172 - 49,996,504 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
RACGAP1Humancongenital dyserythropoietic anemia type IIIb  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Anemia more ...ClinVarPMID:34818416 and PMID:36200420
RACGAP1Humancongenital dyserythropoietic anemia type IIIb  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Anemia more ...ClinVarPMID:36200420
RACGAP1Humancongenital dyserythropoietic anemia type IIIb  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Anemia more ...ClinVarPMID:34818416
Object Symbol
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Term
Qualifier
Evidence
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Reference
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Original Reference(s)
RACGAP1Humanhepatocellular carcinoma  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:28284560
RACGAP1Humanpolycystic ovary syndrome  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:21411543
Object Symbol
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Original Reference(s)
RACGAP1Humancongenital dyserythropoietic anemia type IIIb  IAGP 7240710 OMIM 

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Original Reference(s)
RACGAP1Human(1->4)-beta-D-glucan multiple interactionsISORacgap1 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of RACGAP1 mRNACTDPMID:36331819
RACGAP1Human1,1-dichloroethene increases expressionISORacgap1 (Mus musculus)6480464vinylidene chloride results in increased expression of RACGAP1 mRNACTDPMID:26682919
RACGAP1Human1,2-dimethylhydrazine increases expressionISORacgap1 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of RACGAP1 mRNACTDPMID:22206623
RACGAP1Human1-naphthyl isothiocyanate increases expressionISORacgap1 (Rattus norvegicus)64804641-Naphthylisothiocyanate results in increased expression of RACGAP1 mRNACTDPMID:30723492
RACGAP1Human17alpha-ethynylestradiol affects expressionISORacgap1 (Mus musculus)6480464Ethinyl Estradiol affects the expression of RACGAP1 mRNACTDPMID:17555576
RACGAP1Human17alpha-ethynylestradiol multiple interactionsISORacgap1 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RACGAP1 mRNACTDPMID:17942748
RACGAP1Human17alpha-ethynylestradiol increases expressionISORacgap1 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of RACGAP1 mRNACTDPMID:17942748
RACGAP1Human17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of RACGAP1 mRNACTDPMID:16474171 more ...
RACGAP1Human2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISORacgap1 (Mus musculus)6480464[2 more ...CTDPMID:25510870
RACGAP1Human2,2',5,5'-tetrachlorobiphenyl multiple interactionsISORacgap1 (Mus musculus)6480464[2 more ...CTDPMID:25510870
RACGAP1Human2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORacgap1 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RACGAP1 mRNA and AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of RACGAP1 mRNA]CTDPMID:15034205 and PMID:17942748
RACGAP1Human2,3,7,8-tetrachlorodibenzodioxine affects expressionISORacgap1 (Rattus norvegicus)6480464Tetrachlorodibenzodioxin affects the expression of RACGAP1 mRNACTDPMID:34747641
RACGAP1Human2,3,7,8-tetrachlorodibenzodioxine decreases expressionISORacgap1 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of RACGAP1 mRNACTDPMID:15034205
RACGAP1Human2,3-dimethoxynaphthalene-1,4-dione increases expressionEXP 64804642 more ...CTDPMID:17547211
RACGAP1Human2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISORacgap1 (Mus musculus)64804642 more ...CTDPMID:38648751
RACGAP1Human2-amino-2-deoxy-D-glucopyranose decreases expressionISORacgap1 (Rattus norvegicus)6480464Glucosamine results in decreased expression of RACGAP1 mRNACTDPMID:17109745
RACGAP1Human2-palmitoylglycerol increases expressionEXP 64804642-palmitoylglycerol results in increased expression of RACGAP1 mRNACTDPMID:37199045
RACGAP1Human3-isobutyl-1-methyl-7H-xanthine multiple interactionsEXP 6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of RACGAP1 mRNACTDPMID:28628672
RACGAP1Human3-methylcholanthrene increases expressionISORacgap1 (Mus musculus)6480464Methylcholanthrene results in increased expression of RACGAP1 mRNACTDPMID:20713471
RACGAP1Human4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of RACGAP1 mRNACTDPMID:28628672

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Biological Process
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Original Reference(s)
RACGAP1Humanactomyosin contractile ring assembly involved_inIMP 150520179 PMID:16129829UniProtPMID:16129829
RACGAP1Humancell differentiation involved_inIEAUniProtKB-KW:KW-0221150520179 UniProtGO_REF:0000043
RACGAP1Humancell division involved_inIEAUniProtKB-KW:KW-0132150520179 UniProtGO_REF:0000043
RACGAP1Humanerythrocyte differentiation involved_inIMP 150520179 PMID:34818416UniProtPMID:34818416
RACGAP1Humanmitotic cytokinesis involved_inIMP 150520179 PMID:16236794 and PMID:23235882UniProtPMID:16236794 and PMID:23235882
RACGAP1Humanmitotic cytokinesis involved_inIBAFB:FBgn0086356 more ...150520179 GO_CentralGO_REF:0000033
RACGAP1Humanmitotic cytokinesis involved_inIC 150520179 PMID:18511905UniProtPMID:18511905
RACGAP1Humanmitotic cytokinesis involved_inIDA 150520179 PMID:11085985 and PMID:19468302UniProtPMID:11085985 and PMID:19468302
RACGAP1Humanmitotic spindle midzone assembly involved_inIDA 150520179 PMID:16103226UniProtPMID:16103226
RACGAP1Humanmitotic spindle midzone assembly involved_inIBAPANTHER:PTN001141909 more ...150520179 GO_CentralGO_REF:0000033
RACGAP1Humanmonoatomic ion transport involved_inIEAUniProtKB-KW:KW-0406150520179 UniProtGO_REF:0000043
RACGAP1Humanneuroblast proliferation involved_inISSUniProtKB:Q9WVM1150520179 UniProtGO_REF:0000024
RACGAP1Humanneuroblast proliferation involved_inIEAUniProtKB:Q9WVM1 and ensembl:ENSMUSP00000126417150520179 EnsemblGO_REF:0000107
RACGAP1Humanpositive regulation of cytokinesis involved_inIDA 150520179 PMID:16103226UniProtPMID:16103226
RACGAP1Humanpositive regulation of cytokinesis involved_inIMP 150520179 PMID:11782313 and PMID:15642749UniProtPMID:11782313 and PMID:15642749
RACGAP1Humanregulation of attachment of spindle microtubules to kinetochore involved_inIMP 150520179 PMID:15642749UniProtPMID:15642749
RACGAP1Humanregulation of embryonic development involved_inISSUniProtKB:Q9WVM1150520179 UniProtGO_REF:0000024
RACGAP1Humanregulation of embryonic development involved_inIEAUniProtKB:Q9WVM1 and ensembl:ENSMUSP00000126417150520179 EnsemblGO_REF:0000107
RACGAP1Humanregulation of small GTPase mediated signal transduction involved_inTAS 150520179 ReactomeReactome:R-HSA-9012999
RACGAP1Humanregulation of small GTPase mediated signal transduction involved_inIEAARBA:ARBA00027280150520179 UniProtGO_REF:0000117
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Cellular Component
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Original Reference(s)
RACGAP1Humanacrosomal vesicle located_inIEAUniProtKB-SubCell:SL-0007150520179 UniProtGO_REF:0000044
RACGAP1Humancentralspindlin complex part_ofIDA 150520179 PMID:11782313 and PMID:16236794UniProtPMID:11782313 and PMID:16236794
RACGAP1Humancentralspindlin complex part_ofIBAFB:FBgn0086356 more ...150520179 GO_CentralGO_REF:0000033
RACGAP1Humancleavage furrow located_inIDA 150520179 PMID:16103226UniProtPMID:16103226
RACGAP1Humancleavage furrow is_active_inIBAFB:FBgn0086356 more ...150520179 GO_CentralGO_REF:0000033
RACGAP1Humancleavage furrow located_inIEAUniProtKB-SubCell:SL-0467150520179 UniProtGO_REF:0000044
RACGAP1Humancytoplasm located_inIEAUniProtKB-KW:KW-0963150520179 UniProtGO_REF:0000043
RACGAP1Humancytoplasm located_inIEAUniProtKB-SubCell:SL-0086150520179 UniProtGO_REF:0000044
RACGAP1Humancytoplasmic side of plasma membrane located_inIDA 150520179 PMID:23235882UniProtPMID:23235882
RACGAP1Humancytoplasmic vesicle located_inIEAUniProtKB-KW:KW-0968150520179 UniProtGO_REF:0000043
RACGAP1Humancytoskeleton located_inIEAUniProtKB-KW:KW-0206150520179 UniProtGO_REF:0000043
RACGAP1Humancytosol located_inTAS 150520179 ReactomeReactome:R-HSA-2213248 more ...
RACGAP1Humanextracellular exosome located_inHDA 150520179 PMID:19199708UniProtPMID:19199708
RACGAP1HumanFlemming body located_inIEAUniProtKB-SubCell:SL-0490150520179 UniProtGO_REF:0000044
RACGAP1Humanmembrane located_inIEAUniProtKB-KW:KW-0472150520179 UniProtGO_REF:0000043
RACGAP1Humanmicrotubule located_inIEAUniProtKB-KW:KW-0493150520179 UniProtGO_REF:0000043
RACGAP1Humanmidbody located_inIDA 150520179 PMID:11782313 more ...UniProtPMID:11782313 more ...
RACGAP1Humanmidbody is_active_inIBAPANTHER:PTN001141909 and UniProtKB:Q9H0H5150520179 GO_CentralGO_REF:0000033
RACGAP1Humanmitochondrion located_inHTP 150520179 PMID:34800366FlyBasePMID:34800366
RACGAP1Humanmitotic spindle located_inIMP 150520179 PMID:15642749UniProtPMID:15642749
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Molecular Function
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Original Reference(s)
RACGAP1Humanalpha-tubulin binding enablesIDA 150520179 PMID:11085985UniProtPMID:11085985
RACGAP1Humanbeta-tubulin binding enablesIDA 150520179 PMID:11085985UniProtPMID:11085985
RACGAP1Humangamma-tubulin binding enablesIDA 150520179 PMID:11085985UniProtPMID:11085985
RACGAP1HumanGTPase activator activity enablesIMP 150520179 PMID:15642749UniProtPMID:15642749
RACGAP1HumanGTPase activator activity enablesIBAFB:FBgn0045843 more ...150520179 GO_CentralGO_REF:0000033
RACGAP1HumanGTPase activator activity enablesIDA 150520179 PMID:10979956UniProtPMID:10979956
RACGAP1HumanGTPase activator activity enablesTAS 150520179 ReactomeReactome:R-HSA-9013111 and Reactome:R-HSA-9018806
RACGAP1HumanGTPase activator activity enablesIEAUniProtKB-KW:KW-0343150520179 UniProtGO_REF:0000043
RACGAP1Humanlipid binding enablesIEAUniProtKB-KW:KW-0446150520179 UniProtGO_REF:0000043
RACGAP1Humanmetal ion binding enablesIEAUniProtKB-KW:KW-0479150520179 UniProtGO_REF:0000043
RACGAP1Humanmicrotubule binding enablesIDA 150520179 PMID:11782313UniProtPMID:11782313
RACGAP1Humanphosphatidylinositol-3,4,5-trisphosphate binding enablesIDA 150520179 PMID:23235882UniProtPMID:23235882
RACGAP1Humanprotein binding enablesIPIUniProtKB:O43663150520179 PMID:14744859UniProtPMID:14744859
RACGAP1Humanprotein binding enablesIPIUniProtKB:Q9H8V3150520179 PMID:16103226 more ...UniProtPMID:16103226 more ...
RACGAP1Humanprotein binding enablesIPIUniProtKB:O75154150520179 PMID:18511905IntActPMID:18511905
RACGAP1Humanprotein binding enablesIPIUniProtKB:Q96GD4150520179 PMID:12689593UniProtPMID:12689593
RACGAP1Humanprotein binding enablesIPIUniProtKB:Q00526 more ...150520179 PMID:32296183IntActPMID:32296183
RACGAP1Humanprotein binding enablesIPIUniProtKB:Q9UBU8150520179 PMID:25416956IntActPMID:25416956
RACGAP1Humanprotein binding enablesIPIUniProtKB:Q96RN1150520179 PMID:11278976IntActPMID:11278976
RACGAP1Humanprotein binding enablesIPIUniProtKB:Q9P258150520179 PMID:25074804UniProtPMID:25074804
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Object Symbol
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Original Reference(s)
RACGAP1HumanAbnormal cellular phenotype  IAGP 8699517 HPOORPHA:98870
RACGAP1HumanAbnormal erythrocyte morphology  IAGP 8699517 HPOORPHA:98870
RACGAP1HumanAbnormal erythroid lineage cell morphology  IAGP 8699517 HPOORPHA:98870
RACGAP1HumanAbnormal proerythroblast morphology  IAGP 8699517 HPOORPHA:98870
RACGAP1HumanAnemia  IAGP 8699517 HPOORPHA:98870
RACGAP1HumanAnisocytosis  IAGP 8699517 HPOORPHA:98870
RACGAP1HumanAutosomal recessive inheritance  IAGP 8699517 HPOMIM:619789
RACGAP1HumanChildhood onset  IAGP 8699517 HPOMIM:619789
RACGAP1HumanElevated circulating hepatic transaminase concentration  IAGP 8699517 HPOORPHA:98870
RACGAP1HumanFatigue  IAGP 8699517 HPOORPHA:98870
RACGAP1HumanGingival bleeding  IAGP 8699517 HPOORPHA:98870
RACGAP1HumanHeadache  IAGP 8699517 HPOORPHA:98870
RACGAP1HumanHyperbilirubinemia  IAGP 8699517 HPOORPHA:98870
RACGAP1HumanIncreased circulating iron concentration  IAGP 8699517 HPOORPHA:98870
RACGAP1HumanIncreased mean corpuscular volume  IAGP 8699517 HPOORPHA:98870
RACGAP1HumanIncreased total iron binding capacity  IAGP 8699517 HPOORPHA:98870
RACGAP1HumanMacrocytic anemia  IAGP 8699517 HPOMIM:619789
RACGAP1HumanMacrocytic dyserythropoietic anemia  IAGP 8699517 HPOMIM:619789
RACGAP1HumanMelena  IAGP 8699517 HPOORPHA:98870
RACGAP1HumanOral cavity bleeding  IAGP 8699517 HPOORPHA:98870
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#
Reference Title
Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
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PMID:8125298   PMID:9497316   PMID:9822598   PMID:10655059   PMID:10748082   PMID:10819331   PMID:10979956   PMID:11076863   PMID:11085985   PMID:11230166   PMID:11256614   PMID:11278894  
PMID:11278976   PMID:11782313   PMID:11937491   PMID:11942621   PMID:12432077   PMID:12477932   PMID:12493759   PMID:12577067   PMID:12590651   PMID:12689593   PMID:14702039   PMID:14729465  
PMID:14744859   PMID:15009096   PMID:15284113   PMID:15324660   PMID:15489334   PMID:15489336   PMID:15642749   PMID:15677464   PMID:15728185   PMID:15778465   PMID:15863513   PMID:15872091  
PMID:16103226   PMID:16118207   PMID:16129829   PMID:16169070   PMID:16236794   PMID:16344560   PMID:16381901   PMID:16565220   PMID:16790497   PMID:16964243   PMID:17081983   PMID:17353931  
PMID:17982282   PMID:18201571   PMID:18445686   PMID:18511905   PMID:19015243   PMID:19056985   PMID:19199708   PMID:19460752   PMID:19468300   PMID:19468302   PMID:19531213   PMID:19913121  
PMID:20360068   PMID:20467437   PMID:20628086   PMID:21145461   PMID:21825042   PMID:21873635   PMID:21988832   PMID:22580824   PMID:22683270   PMID:22750944   PMID:22810586   PMID:22927365  
PMID:22939629   PMID:22945935   PMID:23096218   PMID:23135572   PMID:23225332   PMID:23235882   PMID:23458834   PMID:23525949   PMID:23537643   PMID:23665020   PMID:23696789   PMID:24615626  
PMID:24711643   PMID:24807907   PMID:24857844   PMID:25068414   PMID:25074804   PMID:25281560   PMID:25305482   PMID:25416956   PMID:25475728   PMID:25486482   PMID:25568185   PMID:25666610  
PMID:25693804   PMID:25875822   PMID:25947135   PMID:26018753   PMID:26252513   PMID:26344197   PMID:26496610   PMID:26508373   PMID:26602080   PMID:26638075   PMID:26777405   PMID:26778597  
PMID:26839216   PMID:26949251   PMID:26972000   PMID:27121792   PMID:27185834   PMID:27216196   PMID:27248496   PMID:27259241   PMID:27284123   PMID:27576135   PMID:27684187   PMID:27926873  
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RACGAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381249,989,162 - 50,033,440 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1249,976,923 - 50,033,136 (-)EnsemblGRCh38hg38GRCh38
GRCh371250,382,945 - 50,419,277 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361248,669,212 - 48,705,488 (-)NCBINCBI36Build 36hg18NCBI36
Build 341248,669,211 - 48,705,488NCBI
Celera1249,179,065 - 49,215,304 (-)NCBICelera
Cytogenetic Map12q13.12NCBI
HuRef1247,414,446 - 47,451,548 (-)NCBIHuRef
CHM1_11250,349,102 - 50,385,463 (-)NCBICHM1_1
T2T-CHM13v2.01249,952,172 - 49,996,504 (-)NCBIT2T-CHM13v2.0
Racgap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391599,518,377 - 99,549,504 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1599,518,377 - 99,549,537 (-)EnsemblGRCm39 Ensembl
GRCm381599,620,496 - 99,651,656 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1599,620,496 - 99,651,656 (-)EnsemblGRCm38mm10GRCm38
MGSCv371599,450,927 - 99,482,052 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361599,448,530 - 99,479,655 (-)NCBIMGSCv36mm8
Celera15101,775,878 - 101,807,252 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.13NCBI
Racgap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87132,629,789 - 132,659,738 (-)NCBIGRCr8
mRatBN7.27130,750,936 - 130,780,891 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7130,750,936 - 130,780,831 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7132,555,040 - 132,584,440 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07134,780,620 - 134,810,026 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07134,693,146 - 134,722,541 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07141,277,303 - 141,308,849 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7141,277,312 - 141,307,233 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07138,713,215 - 138,728,271 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47138,366,356 - 138,395,716 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17138,443,204 - 138,463,026 (-)NCBI
Celera7127,232,693 - 127,262,334 (-)NCBICelera
Cytogenetic Map7q36NCBI
Racgap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955547581,134 - 616,087 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955547584,885 - 615,883 (-)NCBIChiLan1.0ChiLan1.0
RACGAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21044,163,317 - 44,199,581 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11244,160,108 - 44,196,343 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01238,729,885 - 38,766,063 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11239,625,763 - 39,660,040 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1239,625,796 - 39,672,256 (+)Ensemblpanpan1.1panPan2
RACGAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1274,689,914 - 4,718,181 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl274,689,483 - 4,727,933 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2741,541,242 - 41,569,279 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,737,980 - 4,766,051 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,738,129 - 4,775,802 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1274,702,991 - 4,731,034 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0274,692,808 - 4,720,859 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02741,935,897 - 41,964,171 (-)NCBIUU_Cfam_GSD_1.0
Racgap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494565,468,262 - 65,499,692 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365127,665,208 - 7,689,112 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365127,665,144 - 7,696,615 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RACGAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl515,904,712 - 15,943,609 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1515,894,314 - 15,943,619 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2516,400,485 - 16,403,961 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RACGAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11146,218,987 - 46,260,477 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1146,220,090 - 46,254,602 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037199,866,951 - 199,902,603 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Racgap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248162,273,856 - 2,303,375 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248162,268,879 - 2,303,305 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in RACGAP1
52 total Variants

1 to 10 of 60 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 12q13.12(chr12:49840075-50315208)x3 copy number gain See cases [RCV000051958] Chr12:49840075..50315208 [GRCh38]
Chr12:50233858..50708991 [GRCh37]
Chr12:48520125..48995258 [NCBI36]
Chr12:12q13.12
uncertain significance
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:1-133851895)x3 copy number gain See cases [RCV000258805] Chr12:1..133851895 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic|likely pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902)x3 copy number gain See cases [RCV000510482] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902) copy number gain See cases [RCV000511643] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
NC_000012.11:g.26370251_54361538inv inversion not specified [RCV000714265] Chr12:26370251..54361538 [GRCh37]
Chr12:12p12.1-q13.13
uncertain significance
GRCh37/hg19 12p13.33-q24.33(chr12:621220-133779118)x3 copy number gain not provided [RCV000750253] Chr12:621220..133779118 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:191619-133777645)x3 copy number gain not provided [RCV000750246] Chr12:191619..133777645 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
NM_001319999.2(RACGAP1):c.1578+13G>A single nucleotide variant not provided [RCV001667253] Chr12:49992232 [GRCh38]
Chr12:50386015 [GRCh37]
Chr12:12q13.12
benign
NM_001319999.2(RACGAP1):c.1823+118A>G single nucleotide variant not provided [RCV001609534] Chr12:49990566 [GRCh38]
Chr12:50384349 [GRCh37]
Chr12:12q13.12
benign
1 to 10 of 60 rows

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR192hsa-miR-192-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Microarray//ReFunctional MTI19074876

Predicted Target Of
Summary Value
Count of predictions:4804
Count of miRNA genes:1073
Interacting mature miRNAs:1303
Transcripts:ENST00000312377, ENST00000427314, ENST00000434422, ENST00000454520, ENST00000546595, ENST00000546723, ENST00000546764, ENST00000546786, ENST00000547061, ENST00000547905, ENST00000548158, ENST00000548247, ENST00000548320, ENST00000548598, ENST00000548644, ENST00000548824, ENST00000548961, ENST00000549342, ENST00000549777, ENST00000550149, ENST00000550651, ENST00000551016, ENST00000551145, ENST00000551260, ENST00000551876, ENST00000552004, ENST00000552157, ENST00000552310, ENST00000552921
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597116586GWAS1212660_Hclostridium difficile infection QTL GWAS1212660 (human)0.000003clostridium difficile infection124999056649990567Human
597306068GWAS1402142_Hsphingomyelin measurement QTL GWAS1402142 (human)2e-14sphingomyelin measurement125000100950001010Human
597304916GWAS1400990_Hsphingomyelin measurement QTL GWAS1400990 (human)4e-08sphingomyelin measurement125000100950001010Human
597272582GWAS1368656_HX-12063 measurement QTL GWAS1368656 (human)5e-08X-12063 measurement124999185349991854Human

RACGAP1_9584  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371250,383,080 - 50,383,647UniSTSGRCh37
Build 361248,669,347 - 48,669,914RGDNCBI36
Celera1249,179,200 - 49,179,767RGD
HuRef1247,414,581 - 47,415,148UniSTS
D12S2183  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371250,420,307 - 50,420,399UniSTSGRCh37
Build 361248,706,574 - 48,706,666RGDNCBI36
Celera1249,216,304 - 49,216,396RGD
HuRef1247,452,548 - 47,452,640UniSTS
STS-W72501  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371250,383,003 - 50,383,228UniSTSGRCh37
GRCh371245,456,204 - 45,456,430UniSTSGRCh37
Build 361243,742,471 - 43,742,697RGDNCBI36
Celera1244,259,879 - 44,260,105RGD
Celera1249,179,123 - 49,179,348UniSTS
Cytogenetic Map12q12UniSTS
Cytogenetic Map12q13.12UniSTS
HuRef1247,414,504 - 47,414,729UniSTS
HuRef1242,484,548 - 42,484,774UniSTS
GeneMap99-GB4 RH Map12195.96UniSTS
WI-17598  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371250,419,477 - 50,419,626UniSTSGRCh37
Build 361248,705,744 - 48,705,893RGDNCBI36
Celera1249,215,474 - 49,215,623RGD
Cytogenetic Map12q13.12UniSTS
HuRef1247,451,718 - 47,451,867UniSTS
GeneMap99-GB4 RH Map12226.06UniSTS
Whitehead-RH Map12324.2UniSTS




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2251 4973 1726 2351 5 624 1951 465 2269 7303 6469 53 3734 1 852 1744 1617 175 1


1 to 30 of 71 rows
RefSeq Transcripts NM_001126103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001126104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001319999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001320000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001320001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001320002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001320003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001320004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001320005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001320006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001320007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006719359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011538238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011538243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017019220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017019221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017019222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017019223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017019224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017019225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017019226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017019227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047428745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047428746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047428747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047428748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047428749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047428750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 30 of 71 rows

Ensembl Acc Id: ENST00000312377   ⟹   ENSP00000309871
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1249,989,162 - 50,025,494 (-)Ensembl
Ensembl Acc Id: ENST00000427314   ⟹   ENSP00000404190
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1249,989,162 - 50,025,438 (-)Ensembl
Ensembl Acc Id: ENST00000454520   ⟹   ENSP00000404808
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1249,989,164 - 50,025,400 (-)Ensembl
Ensembl Acc Id: ENST00000546595   ⟹   ENSP00000449963
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1250,001,172 - 50,025,416 (-)Ensembl
Ensembl Acc Id: ENST00000546723   ⟹   ENSP00000449669
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1250,004,265 - 50,025,436 (-)Ensembl
Ensembl Acc Id: ENST00000546764   ⟹   ENSP00000447177
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1250,005,264 - 50,025,483 (-)Ensembl
Ensembl Acc Id: ENST00000546786   ⟹   ENSP00000447429
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1250,001,171 - 50,025,463 (-)Ensembl
Ensembl Acc Id: ENST00000547061
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1249,997,069 - 50,002,691 (-)Ensembl
Ensembl Acc Id: ENST00000547905   ⟹   ENSP00000449370
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1249,990,268 - 50,025,494 (-)Ensembl
Ensembl Acc Id: ENST00000548158
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1249,999,310 - 50,004,271 (-)Ensembl
Ensembl Acc Id: ENST00000548247   ⟹   ENSP00000450074
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1250,005,256 - 50,033,136 (-)Ensembl
Ensembl Acc Id: ENST00000548320   ⟹   ENSP00000448507
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1249,997,131 - 50,025,493 (-)Ensembl
Ensembl Acc Id: ENST00000548598   ⟹   ENSP00000449574
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1249,997,160 - 50,025,461 (-)Ensembl
Ensembl Acc Id: ENST00000548644   ⟹   ENSP00000449620
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1250,004,234 - 50,025,451 (-)Ensembl
Ensembl Acc Id: ENST00000548824   ⟹   ENSP00000449170
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1250,002,272 - 50,025,434 (-)Ensembl
Ensembl Acc Id: ENST00000548961   ⟹   ENSP00000446889
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1249,976,923 - 49,992,358 (-)Ensembl
Ensembl Acc Id: ENST00000549342   ⟹   ENSP00000449565
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1249,992,079 - 49,999,736 (-)Ensembl
Ensembl Acc Id: ENST00000549777   ⟹   ENSP00000448707
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1250,005,294 - 50,025,435 (-)Ensembl
Ensembl Acc Id: ENST00000550149   ⟹   ENSP00000446642
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1249,999,675 - 50,025,477 (-)Ensembl
Ensembl Acc Id: ENST00000550651   ⟹   ENSP00000449959
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1250,005,347 - 50,025,494 (-)Ensembl
Ensembl Acc Id: ENST00000551016   ⟹   ENSP00000449374
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1249,989,979 - 50,016,720 (-)Ensembl
Ensembl Acc Id: ENST00000551145   ⟹   ENSP00000450064
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1250,002,248 - 50,025,518 (-)Ensembl
Ensembl Acc Id: ENST00000551260   ⟹   ENSP00000448860
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1250,004,234 - 50,025,435 (-)Ensembl
Ensembl Acc Id: ENST00000551876   ⟹   ENSP00000449186
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1250,005,291 - 50,017,084 (-)Ensembl
Ensembl Acc Id: ENST00000552004   ⟹   ENSP00000448136
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1250,005,358 - 50,025,488 (-)Ensembl
Ensembl Acc Id: ENST00000552157   ⟹   ENSP00000448968
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1250,005,256 - 50,025,443 (-)Ensembl
Ensembl Acc Id: ENST00000552310   ⟹   ENSP00000448697
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1249,999,139 - 50,025,448 (-)Ensembl
Ensembl Acc Id: ENST00000552921   ⟹   ENSP00000447393
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1250,004,278 - 50,025,557 (-)Ensembl
RefSeq Acc Id: NM_001126103   ⟹   NP_001119575
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
GRCh371250,382,945 - 50,425,586 (-)NCBI
HuRef1247,414,446 - 47,451,548 (-)ENTREZGENE
CHM1_11250,349,102 - 50,385,496 (-)NCBI
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001126104   ⟹   NP_001119576
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
GRCh371250,382,945 - 50,425,586 (-)NCBI
HuRef1247,414,446 - 47,451,548 (-)ENTREZGENE
CHM1_11250,349,102 - 50,385,496 (-)NCBI
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001319999   ⟹   NP_001306928
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
CHM1_11250,349,102 - 50,385,496 (-)NCBI
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001320000   ⟹   NP_001306929
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
CHM1_11250,349,102 - 50,385,496 (-)NCBI
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001320001   ⟹   NP_001306930
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
CHM1_11250,349,102 - 50,385,496 (-)NCBI
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001320002   ⟹   NP_001306931
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
CHM1_11250,349,102 - 50,385,496 (-)NCBI
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001320003   ⟹   NP_001306932
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
CHM1_11250,349,102 - 50,385,496 (-)NCBI
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001320004   ⟹   NP_001306933
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
CHM1_11250,349,102 - 50,385,496 (-)NCBI
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001320005   ⟹   NP_001306934
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
CHM1_11250,349,102 - 50,385,496 (-)NCBI
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001320006   ⟹   NP_001306935
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
CHM1_11250,349,102 - 50,385,496 (-)NCBI
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001320007   ⟹   NP_001306936
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
CHM1_11250,349,102 - 50,385,496 (-)NCBI
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
Sequence:
RefSeq Acc Id: NM_013277   ⟹   NP_037409
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
GRCh371250,382,945 - 50,425,586 (-)NCBI
Build 361248,669,212 - 48,705,488 (-)NCBI Archive
HuRef1247,414,446 - 47,451,548 (-)ENTREZGENE
CHM1_11250,349,102 - 50,385,496 (-)NCBI
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006719359   ⟹   XP_006719422
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011538238   ⟹   XP_011536540
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,031,715 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017019221   ⟹   XP_016874710
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017019222   ⟹   XP_016874711
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017019223   ⟹   XP_016874712
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017019224   ⟹   XP_016874713
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017019225   ⟹   XP_016874714
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017019226   ⟹   XP_016874715
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,018,589 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017019227   ⟹   XP_016874716
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024448958   ⟹   XP_024304726
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,033,440 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047428745   ⟹   XP_047284701
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
RefSeq Acc Id: XM_047428746   ⟹   XP_047284702
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
RefSeq Acc Id: XM_047428747   ⟹   XP_047284703
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
RefSeq Acc Id: XM_047428748   ⟹   XP_047284704
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
RefSeq Acc Id: XM_047428749   ⟹   XP_047284705
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
RefSeq Acc Id: XM_047428750   ⟹   XP_047284706
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
RefSeq Acc Id: XM_047428751   ⟹   XP_047284707
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381249,989,162 - 50,025,494 (-)NCBI
RefSeq Acc Id: XM_054371859   ⟹   XP_054227834
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01249,952,172 - 49,996,504 (-)NCBI
RefSeq Acc Id: XM_054371860   ⟹   XP_054227835
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
RefSeq Acc Id: XM_054371861   ⟹   XP_054227836
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
RefSeq Acc Id: XM_054371862   ⟹   XP_054227837
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
RefSeq Acc Id: XM_054371863   ⟹   XP_054227838
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
RefSeq Acc Id: XM_054371864   ⟹   XP_054227839
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
RefSeq Acc Id: XM_054371865   ⟹   XP_054227840
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
RefSeq Acc Id: XM_054371866   ⟹   XP_054227841
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
RefSeq Acc Id: XM_054371867   ⟹   XP_054227842
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01249,952,172 - 49,994,778 (-)NCBI
RefSeq Acc Id: XM_054371868   ⟹   XP_054227843
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
RefSeq Acc Id: XM_054371869   ⟹   XP_054227844
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
RefSeq Acc Id: XM_054371870   ⟹   XP_054227845
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
RefSeq Acc Id: XM_054371871   ⟹   XP_054227846
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01249,952,172 - 49,981,633 (-)NCBI
RefSeq Acc Id: XM_054371872   ⟹   XP_054227847
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
RefSeq Acc Id: XM_054371873   ⟹   XP_054227848
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
RefSeq Acc Id: XM_054371874   ⟹   XP_054227849
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
RefSeq Acc Id: XM_054371875   ⟹   XP_054227850
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01249,952,172 - 49,988,556 (-)NCBI
1 to 30 of 69 rows
Protein RefSeqs NP_001119575 (Get FASTA)   NCBI Sequence Viewer  
  NP_001119576 (Get FASTA)   NCBI Sequence Viewer  
  NP_001306928 (Get FASTA)   NCBI Sequence Viewer  
  NP_001306929 (Get FASTA)   NCBI Sequence Viewer  
  NP_001306930 (Get FASTA)   NCBI Sequence Viewer  
  NP_001306931 (Get FASTA)   NCBI Sequence Viewer  
  NP_001306932 (Get FASTA)   NCBI Sequence Viewer  
  NP_001306933 (Get FASTA)   NCBI Sequence Viewer  
  NP_001306934 (Get FASTA)   NCBI Sequence Viewer  
  NP_001306935 (Get FASTA)   NCBI Sequence Viewer  
  NP_001306936 (Get FASTA)   NCBI Sequence Viewer  
  NP_037409 (Get FASTA)   NCBI Sequence Viewer  
  XP_006719422 (Get FASTA)   NCBI Sequence Viewer  
  XP_011536540 (Get FASTA)   NCBI Sequence Viewer  
  XP_016874710 (Get FASTA)   NCBI Sequence Viewer  
  XP_016874711 (Get FASTA)   NCBI Sequence Viewer  
  XP_016874712 (Get FASTA)   NCBI Sequence Viewer  
  XP_016874713 (Get FASTA)   NCBI Sequence Viewer  
  XP_016874714 (Get FASTA)   NCBI Sequence Viewer  
  XP_016874715 (Get FASTA)   NCBI Sequence Viewer  
  XP_016874716 (Get FASTA)   NCBI Sequence Viewer  
  XP_024304726 (Get FASTA)   NCBI Sequence Viewer  
  XP_047284701 (Get FASTA)   NCBI Sequence Viewer  
  XP_047284702 (Get FASTA)   NCBI Sequence Viewer  
  XP_047284703 (Get FASTA)   NCBI Sequence Viewer  
  XP_047284704 (Get FASTA)   NCBI Sequence Viewer  
  XP_047284705 (Get FASTA)   NCBI Sequence Viewer  
  XP_047284706 (Get FASTA)   NCBI Sequence Viewer  
  XP_047284707 (Get FASTA)   NCBI Sequence Viewer  
  XP_054227834 (Get FASTA)   NCBI Sequence Viewer  
1 to 30 of 69 rows
1 to 5 of 72 rows
1 to 5 of 72 rows
RefSeq Acc Id: NP_001119575   ⟸   NM_001126103
- Peptide Label: isoform a
- UniProtKB: Q9P250 (UniProtKB/Swiss-Prot),   Q9NWN2 (UniProtKB/Swiss-Prot),   Q6PJ26 (UniProtKB/Swiss-Prot),   Q9P2W2 (UniProtKB/Swiss-Prot),   Q9H0H5 (UniProtKB/Swiss-Prot),   B2RE34 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_037409   ⟸   NM_013277
- Peptide Label: isoform a
- UniProtKB: Q9P250 (UniProtKB/Swiss-Prot),   Q9NWN2 (UniProtKB/Swiss-Prot),   Q6PJ26 (UniProtKB/Swiss-Prot),   Q9P2W2 (UniProtKB/Swiss-Prot),   Q9H0H5 (UniProtKB/Swiss-Prot),   B2RE34 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001119576   ⟸   NM_001126104
- Peptide Label: isoform a
- UniProtKB: Q9P250 (UniProtKB/Swiss-Prot),   Q9NWN2 (UniProtKB/Swiss-Prot),   Q6PJ26 (UniProtKB/Swiss-Prot),   Q9P2W2 (UniProtKB/Swiss-Prot),   Q9H0H5 (UniProtKB/Swiss-Prot),   B2RE34 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006719422   ⟸   XM_006719359
- Peptide Label: isoform X3
- UniProtKB: Q9P250 (UniProtKB/Swiss-Prot),   Q9NWN2 (UniProtKB/Swiss-Prot),   Q6PJ26 (UniProtKB/Swiss-Prot),   Q9P2W2 (UniProtKB/Swiss-Prot),   Q9H0H5 (UniProtKB/Swiss-Prot),   B2RE34 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011536540   ⟸   XM_011538238
- Peptide Label: isoform X3
- UniProtKB: Q9P250 (UniProtKB/Swiss-Prot),   Q9NWN2 (UniProtKB/Swiss-Prot),   Q6PJ26 (UniProtKB/Swiss-Prot),   Q9P2W2 (UniProtKB/Swiss-Prot),   Q9H0H5 (UniProtKB/Swiss-Prot),   B2RE34 (UniProtKB/TrEMBL)
- Sequence:
Phorbol-ester/DAG-type   Rho-GAP

Name Modeler Protein Id AA Range Protein Structure
AF-Q9H0H5-F1-model_v2 AlphaFold Q9H0H5 1-632 view protein structure

RGD ID:6790414
Promoter ID:HG_KWN:15591
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001126103,   NM_001126104,   NM_013277,   UC001RVU.2
Position:
Human AssemblyChrPosition (strand)Source
Build 361248,705,364 - 48,705,864 (-)MPROMDB
RGD ID:6852692
Promoter ID:EP74158
Type:single initiation site
Name:HS_RACGAP1
Description:Rac GTPase activating protein 1.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Mammalian gene collection (MGC) full-length cDNA cloning
Position:
Human AssemblyChrPosition (strand)Source
Build 361248,705,544 - 48,705,604EPD
RGD ID:6810384
Promoter ID:HG_ACW:16884
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:NB4
Transcripts:RACGAP1.VEAPR07
Position:
Human AssemblyChrPosition (strand)Source
Build 361248,713,216 - 48,713,716 (-)MPROMDB
RGD ID:7223869
Promoter ID:EPDNEW_H17680
Type:initiation region
Name:RACGAP1_1
Description:Rac GTPase activating protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381250,025,452 - 50,025,512EPDNEW


1 to 40 of 69 rows
Database
Acc Id
Source(s)
COSMIC RACGAP1 COSMIC
Ensembl Genes ENSG00000161800 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000312377 ENTREZGENE
  ENST00000312377.10 UniProtKB/Swiss-Prot
  ENST00000427314 ENTREZGENE
  ENST00000427314.6 UniProtKB/Swiss-Prot
  ENST00000454520 ENTREZGENE
  ENST00000454520.6 UniProtKB/Swiss-Prot
  ENST00000547905 ENTREZGENE
  ENST00000547905.5 UniProtKB/Swiss-Prot
  ENST00000551016 ENTREZGENE
  ENST00000551016.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.555.10 UniProtKB/Swiss-Prot
  3.30.60.20 UniProtKB/Swiss-Prot
GTEx ENSG00000161800 GTEx
HGNC ID HGNC:9804 ENTREZGENE
Human Proteome Map RACGAP1 Human Proteome Map
InterPro C1-like_sf UniProtKB/Swiss-Prot
  PE/DAG-bd UniProtKB/Swiss-Prot
  Rho_GTPase_activation_prot UniProtKB/Swiss-Prot
  RhoGAP_dom UniProtKB/Swiss-Prot
KEGG Report hsa:29127 UniProtKB/Swiss-Prot
NCBI Gene 29127 ENTREZGENE
OMIM 604980 OMIM
PANTHER RAC GTPASE-ACTIVATING PROTEIN 1 UniProtKB/Swiss-Prot
  RAC GTPASE-ACTIVATING PROTEIN 1 UniProtKB/Swiss-Prot
Pfam C1_1 UniProtKB/Swiss-Prot
  RhoGAP UniProtKB/Swiss-Prot
PharmGKB PA34165 PharmGKB
PROSITE RHOGAP UniProtKB/Swiss-Prot
  ZF_DAG_PE_1 UniProtKB/Swiss-Prot
  ZF_DAG_PE_2 UniProtKB/Swiss-Prot
SMART RhoGAP UniProtKB/Swiss-Prot
  SM00109 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48350 UniProtKB/Swiss-Prot
  SSF57889 UniProtKB/Swiss-Prot
UniProt A0A2X0U4T9_HUMAN UniProtKB/TrEMBL
  B2RE34 ENTREZGENE, UniProtKB/TrEMBL
  F8VQF5_HUMAN UniProtKB/TrEMBL
  F8VQZ5_HUMAN UniProtKB/TrEMBL
1 to 40 of 69 rows