Racgap1 (Rac GTPase activating protein 1) - Rat Genome Database

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Gene: Racgap1 (Rac GTPase activating protein 1) Heterocephalus glaber
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Symbol: Racgap1
Name: Rac GTPase activating protein 1
RGD ID: 18932802
Description: ENCODES a protein that exhibits alpha-tubulin binding (inferred); beta-tubulin binding (inferred); gamma-tubulin binding (inferred); INVOLVED IN actomyosin contractile ring assembly (inferred); erythrocyte differentiation (inferred); mitotic cytokinesis (inferred); ASSOCIATED WITH Congenital Dyserythropoietic Anemia Type IIIb (ortholog); hepatocellular carcinoma (ortholog); polycystic ovary syndrome (ortholog); FOUND IN mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: rac GTPase-activating protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248162,273,856 - 2,303,375 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248162,268,879 - 2,303,305 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:21993625   PMID:22301074  


Genomics

Comparative Map Data
Racgap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248162,273,856 - 2,303,375 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248162,268,879 - 2,303,305 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
RACGAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381249,989,162 - 50,033,440 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1249,976,923 - 50,033,136 (-)EnsemblGRCh38hg38GRCh38
GRCh371250,382,945 - 50,419,277 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361248,669,212 - 48,705,488 (-)NCBINCBI36Build 36hg18NCBI36
Build 341248,669,211 - 48,705,488NCBI
Celera1249,179,065 - 49,215,304 (-)NCBICelera
Cytogenetic Map12q13.12NCBI
HuRef1247,414,446 - 47,451,548 (-)NCBIHuRef
CHM1_11250,349,102 - 50,385,463 (-)NCBICHM1_1
T2T-CHM13v2.01249,952,172 - 49,996,504 (-)NCBIT2T-CHM13v2.0
Racgap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391599,518,377 - 99,549,504 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1599,518,377 - 99,549,537 (-)EnsemblGRCm39 Ensembl
GRCm381599,620,496 - 99,651,656 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1599,620,496 - 99,651,656 (-)EnsemblGRCm38mm10GRCm38
MGSCv371599,450,927 - 99,482,052 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361599,448,530 - 99,479,655 (-)NCBIMGSCv36mm8
Celera15101,775,878 - 101,807,252 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.13NCBI
Racgap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87132,629,789 - 132,659,738 (-)NCBIGRCr8
mRatBN7.27130,750,936 - 130,780,891 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7130,750,936 - 130,780,831 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7132,555,040 - 132,584,440 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07134,780,620 - 134,810,026 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07134,693,146 - 134,722,541 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07141,277,303 - 141,308,849 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7141,277,312 - 141,307,233 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07138,713,215 - 138,728,271 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47138,366,356 - 138,395,716 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17138,443,204 - 138,463,026 (-)NCBI
Celera7127,232,693 - 127,262,334 (-)NCBICelera
Cytogenetic Map7q36NCBI
Racgap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955547581,134 - 616,087 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955547584,885 - 615,883 (-)NCBIChiLan1.0ChiLan1.0
RACGAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21044,163,317 - 44,199,581 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11244,160,108 - 44,196,343 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01238,729,885 - 38,766,063 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11239,625,763 - 39,660,040 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1239,625,796 - 39,672,256 (+)Ensemblpanpan1.1panPan2
RACGAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1274,689,914 - 4,718,181 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl274,689,483 - 4,727,933 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2741,541,242 - 41,569,279 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,737,980 - 4,766,051 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,738,129 - 4,775,802 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1274,702,991 - 4,731,034 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0274,692,808 - 4,720,859 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02741,935,897 - 41,964,171 (-)NCBIUU_Cfam_GSD_1.0
Racgap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494565,468,262 - 65,499,692 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365127,665,208 - 7,689,112 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365127,665,144 - 7,696,615 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RACGAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl515,904,712 - 15,943,609 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1515,894,314 - 15,943,619 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2516,400,485 - 16,403,961 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RACGAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11146,218,987 - 46,260,477 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1146,220,090 - 46,254,602 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037199,866,951 - 199,902,603 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000008114   ⟹   ENSHGLP00000008026
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248162,273,856 - 2,303,375 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000008115   ⟹   ENSHGLP00000008027
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248162,281,861 - 2,303,375 (+)Ensembl
RefSeq Acc Id: XM_004863000   ⟹   XP_004863057
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248162,274,457 - 2,303,305 (+)NCBI
RefSeq Acc Id: XM_004863001   ⟹   XP_004863058
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248162,274,478 - 2,303,305 (+)NCBI
RefSeq Acc Id: XM_004863002   ⟹   XP_004863059
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248162,268,900 - 2,303,305 (+)NCBI
RefSeq Acc Id: XM_013079085   ⟹   XP_012934539
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248162,274,457 - 2,303,305 (+)NCBI
RefSeq Acc Id: XM_021243112   ⟹   XP_021098771
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248162,268,879 - 2,303,305 (+)NCBI
RefSeq Acc Id: XM_021243113   ⟹   XP_021098772
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248162,278,643 - 2,303,305 (+)NCBI
RefSeq Acc Id: XM_021243114   ⟹   XP_021098773
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248162,274,384 - 2,303,305 (+)NCBI
RefSeq Acc Id: XM_021243115   ⟹   XP_021098774
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248162,268,893 - 2,303,305 (+)NCBI
RefSeq Acc Id: XM_021243116   ⟹   XP_021098775
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248162,288,388 - 2,303,305 (+)NCBI
RefSeq Acc Id: XM_021243117   ⟹   XP_021098776
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248162,268,927 - 2,303,305 (+)NCBI
RefSeq Acc Id: XP_021098771   ⟸   XM_021243112
- Peptide Label: isoform X1
- UniProtKB: G5AU06 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098774   ⟸   XM_021243115
- Peptide Label: isoform X1
- UniProtKB: G5AU06 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004863059   ⟸   XM_004863002
- Peptide Label: isoform X1
- UniProtKB: G5AU06 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098776   ⟸   XM_021243117
- Peptide Label: isoform X2
RefSeq Acc Id: XP_021098773   ⟸   XM_021243114
- Peptide Label: isoform X1
- UniProtKB: G5AU06 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004863057   ⟸   XM_004863000
- Peptide Label: isoform X1
- UniProtKB: G5AU06 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012934539   ⟸   XM_013079085
- Peptide Label: isoform X1
- UniProtKB: G5AU06 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004863058   ⟸   XM_004863001
- Peptide Label: isoform X1
- UniProtKB: G5AU06 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098772   ⟸   XM_021243113
- Peptide Label: isoform X1
- UniProtKB: G5AU06 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098775   ⟸   XM_021243116
- Peptide Label: isoform X2
Ensembl Acc Id: ENSHGLP00000008026   ⟸   ENSHGLT00000008114
Ensembl Acc Id: ENSHGLP00000008027   ⟸   ENSHGLT00000008115


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000005812 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000008114 ENTREZGENE
  ENSHGLT00000008115 ENTREZGENE
Gene3D-CATH 1.10.555.10 UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/TrEMBL
InterPro C1-like_sf UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
KEGG Report hgl:101704773 UniProtKB/TrEMBL
NCBI Gene Racgap1 ENTREZGENE
PANTHER RAC GTPASE-ACTIVATING PROTEIN 1 UniProtKB/TrEMBL
  RAC GTPASE-ACTIVATING PROTEIN 1 UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
PROSITE RHOGAP UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/TrEMBL
SMART RhoGAP UniProtKB/TrEMBL
  SM00109 UniProtKB/TrEMBL
Superfamily-SCOP SSF48350 UniProtKB/TrEMBL
  SSF57889 UniProtKB/TrEMBL
UniProt G5AU06 ENTREZGENE, UniProtKB/TrEMBL