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Gene: KNDC1 (kinase non-catalytic C-lobe domain containing 1) Pan paniscus

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Symbol:

KNDC1

Name:

kinase non-catalytic C-lobe domain containing 1

RGD ID:

12001236

Description:

ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); INVOLVED IN cerebellar granule cell differentiation (ortholog); positive regulation of protein phosphorylation (ortholog); regulation of dendrite development (ortholog); ASSOCIATED WITH breast ductal carcinoma (ortholog); distal 10q deletion syndrome (ortholog); invasive ductal carcinoma (ortholog); FOUND IN dendrite (inferred); guanyl-nucleotide exchange factor complex (inferred); neuronal cell body (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

kinase non-catalytic C-lobe domain-containing protein 1; kinase non-catalytic C-lobe domain-containing protein 1-like; LOC117977854

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	145,280,055 - 145,347,627 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	145,285,422 - 145,352,984 (+)	NCBI		NHGRI_mPanPan1
PanPan1.1	10	134,068,896 - 134,133,240 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	134,068,936 - 134,132,964 (+)	Ensembl	panpan1.1		panPan2

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

breast ductal carcinoma (ISO)

distal 10q deletion syndrome (ISO)

invasive ductal carcinoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cerebellar granule cell differentiation (IEA,ISO)

positive regulation of protein phosphorylation (ISO)

regulation of dendrite development (IEA,ISO)

regulation of dendrite morphogenesis (IEA,ISO)

small GTPase-mediated signal transduction (IEA)

Cellular Component

dendrite (IEA)

guanyl-nucleotide exchange factor complex (IEA)

neuronal cell body (IEA)

Molecular Function

guanyl-nucleotide exchange factor activity (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

KNDC1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	145,280,055 - 145,347,627 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	145,285,422 - 145,352,984 (+)	NCBI		NHGRI_mPanPan1
PanPan1.1	10	134,068,896 - 134,133,240 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	134,068,936 - 134,132,964 (+)	Ensembl	panpan1.1		panPan2

KNDC1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	133,160,219 - 133,226,412 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	133,160,219 - 133,226,412 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	134,973,723 - 135,039,916 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	134,823,961 - 134,889,906 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	134,862,851 - 134,928,797	NCBI
Celera	10	128,476,610 - 128,543,501 (-)	NCBI		Celera
Cytogenetic Map	10	q26.3	NCBI
HuRef	10	128,521,729 - 128,586,432 (+)	NCBI		HuRef
CHM1_1	10	135,255,842 - 135,320,740 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	134,116,905 - 134,181,903 (+)	NCBI		T2T-CHM13v2.0

Kndc1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	139,474,612 - 139,521,453 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	139,474,612 - 139,521,450 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	139,894,696 - 139,941,540 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	139,894,696 - 139,941,537 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	147,080,595 - 147,127,439 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	139,746,158 - 139,792,859 (+)	NCBI		MGSCv36	mm8
Celera	7	139,698,438 - 139,745,432 (+)	NCBI		Celera
Cytogenetic Map	7	F4	NCBI
cM Map	7	84.89	NCBI

Kndc1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	204,119,597 - 204,167,967 (+)	NCBI		GRCr8
mRatBN7.2	1	194,689,962 - 194,738,353 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	194,690,135 - 194,738,362 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	1	212,229,751 - 212,279,254 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	212,230,259 - 212,277,694 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	219,151,852 - 219,198,195 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	199,723,472 - 199,750,125 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	192,367,174 - 192,415,923 (+)	NCBI		Celera
Cytogenetic Map	1	q41	NCBI

Kndc1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955477	10,792,394 - 10,850,186 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955477	10,792,066 - 10,850,457 (+)	NCBI	ChiLan1.0	ChiLan1.0

KNDC1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	40,757,950 - 40,790,603 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	40,830,621 - 40,880,576 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	41,412,067 - 41,462,358 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	28	41,411,586 - 41,463,264 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	28	40,894,538 - 40,944,710 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	40,884,360 - 40,934,777 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	41,286,840 - 41,337,321 (+)	NCBI		UU_Cfam_GSD_1.0

Kndc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	6,220,171 - 6,273,828 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936486	19,287,462 - 19,341,145 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936486	19,287,468 - 19,341,127 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KNDC1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	141,132,350 - 141,188,342 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	141,132,374 - 141,188,343 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	153,094,627 - 153,149,088 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KNDC1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Vero_WHO_p1.0	NW_023666048	87,486,921 - 87,586,133 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Kndc1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624737	13,518,818 - 13,577,762 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624737	13,516,881 - 13,577,795 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003816259	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034951477	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034951479	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000054610 ⟹ ENSPPAP00000031745

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	10	134,068,936 - 134,132,964 (+)	Ensembl

RefSeq Acc Id:

XM_003816259 ⟹ XP_003816307

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	145,280,086 - 145,347,627 (+)	NCBI
NHGRI_mPanPan1	10	145,285,458 - 145,352,984 (+)	NCBI
PanPan1.1	10	134,068,896 - 134,133,240 (+)	NCBI

Sequence:

show sequence

AGCCGGAGGCCCCGGGGGCGGTGCGCGGCGCGGCCGCAGGATGCAGGCCATGGACCCGGCCGCG
GCGGATCTCTACGAGGAGGACGGCAAAGACCTGGACTTCTACGACTTCGAGCCGCTGCCCACCC
TCCCCGAGGACGAGGAGAACGTGTCTCTGGCTGACATCCTCTCCCTGCGGGACCGTGGCCTCAG
CGAGCAGGAAGCCTGGGCCGTGTGCCTGGAGTGCAGCCTGTCCATGCGGAGCGTGGCCCACGCC
GCCATCTTCCAGAGCCTGTGCATCACGCCCGACACCCTGGCCTTCAACACCAGCGGGAACGTGT
GTTTCATGGAGCAGCTCAGCGACGACCCTGAGGGTGCCTTCGTTCCCCCCGAGTTCGACGTGAC
CGGGAACACCTTTGAGGCGCACATCTACTCTCTGGGGGCCACGCTGAAGGCCGCCCTCGAGTAC
GTGGCAGAGCCCACACTGGAACCCAGGCTGAGCCAAGACCTCGAGGCGCTGCTGAGCCGGATGC
AGGCGGAGGACCCCGGGGACCGGCCGGACCTCGAGAGCATCATCGCGCTGTGTGAAGAGAAGCT
GCAGCTCACATCCTCCTGTCGCATGTGCCGGAGCCTCTCTGCTGTGGGGAGGAGGGTTCTCTCC
ATCGAGTCCTTCGGAGCGCTGCAGGATGTCAGCGAGAGCAGCTGGCGGGAGAGACCTGCCCCAG
GAAACGCTGGGCCCAGGAGGCCGCCCGGGGACCCCAGCACTGACCCGGAGGTTCTGCCAACCCC
CGAAGGCCCAGAGTCTGAGACCAGCCGGGGCCCCAGAGCCTCCCCAACGAAGGCTCTGCTGTCC
ACCCCGGTGAGAAATGGCGAGAGCCACAGCCGGGAGGGGCTGGCCGGCCTCGTCCTGGATGCCG
AGCGCACCCTCGGGGAGCTGGACAGAGACGCCCTCAGGAGAAGCCGCCTGCGGAAGGTGCAGAC
GTTCCCTAGGCTGCTGTCCGACAGCCCCGAGGCCACCCTCTGCCTGCCGCTGACCCGCGGGAAA
AGCCAGCTGCCCATGTCAGAATTATTCTCTCCAGACCCCAGGAAGGCTTTTCTGGACAGGAAAA
ATGGCCTTTCTAGCTTCCAGGCTCAGCCCAAATGCAGGCTGTGGCCGGAGCAGGAGCCGGAACA
CCAGCTGGGATGGGTTCCCTGTGCAGGCCGCAGCGCGGACAGGGGCCCTGGGGTGCCCGGCAGT
CCAGGACAGCCCGAGACTTCACACCCCAGCCAGGGGCCAGCAGAGGCCAGACCCCCACCCTGCC
CTGCAGACCCTCGAGATGCTAGCGGCGAAGCCCAGACTCCCAGGGACGATGAGAGAATTCCAGA
AGGAGCCAGGCAGCTGGAAAGTGCAGCCGCGGAGCAGTGGGTGTCCCTGCAGGAACTCCTGTCC
CAGCTGGGCCGGCCCTTCCGGGAGTACGAGCTGTGGGCCCTGTGCCTGGCCTGCCTCCGCGCAC
TGCAGACACGCCCTGAGCACCCAGCCTACCTGTGTCTGGACTCCGTGCTGGTTGCTGAGGATGG
GGCTGTGCTCTTCCAGCCACCCCCTGCCAACGGTTCCTATGACTCGTTCTTTCTGGCTCCTGAG
CTGGCAGAGGAGAGGCTGGTAACTGAAAAGGCCTCTGTGTACTGTGTGGCCGCCGTTCTGTGGA
CCGCAGCCAAGTTCAGCGTCCCCCGCAACCACAAGCTGGCCCTGCCACGCAGGCTCAAGACCCT
CCTCCTGGACATGGCCAGGCGCAGTGCCCCGGAGCGGCCATCCGCGGCTGAGGCCATCAAGGTG
TGCGGCAGCTACCTCCTCCAGCGAGGCATGGACAGCCGGAAAATCCTTGCCCACCTCAGAGCTT
CCATCTGCCAGGTGTACCAGGAGAAAGAGACCATCAGCCTCCAAAACGCCTTCTCAGTGGTTGA
ACTGAAGCCCAGTGTGGCACCAGCCCCAGAGCCCAGCCCAGGCTTCCTGCCGGTGAACAGCGAC
ACCGGGCTTGTGGCTGTGCCAGGGCCCGTGCCCAGCCAGCACCCCTGCGGTGAAGAAGCCACCC
AGCTGCCTGCGGCGTTCACCTCCGAGGCCACGCACTTCAAGCCCATTGTCCTCGCACAGGACGC
AAGTGTGGCCAGGGACCAGCCTGCCTTGGCCCAGGAGGAGTCCGAGGAGAGGGGCGGCCAGAGG
GAGGGAGAAGGTGAGGAGAAGCTCTCCCCGGAGGCCCACGCTGGGTGCCCCAGCCTGAAGACGC
CTGACGGGCCGGTGCCTGGCCCGGGGCCACAGGGAGCAGCCCCAGAGCCTCTTGGGGCGTCAGT
GCAGCGTGACTCAGCCCAGGGCCGCCCCTGCCCTCCACCCCAGGCCCCAGCAAACCAGCCAGAG
GGGGCCTCATCGGCAGCTCCCGGCTCTCCAGTCCCCGCCCCGCCCACGAAGGCATCTGCGCTGC
CCGTAGAGCAAGGGCCGGCTGAGCCAATCCTACCTGGAGTTGCTTCCGGGGGCCTCAGGCCCGA
CGCCCTGGGGCCCACCACGGCCCACCACGGCCCACGCCACCCGCCCAAGCCCCCACGAAGCAAG
GCCACCGAGCGCCCGGGCCGGGAGCCAGAGGGCCCCGGGGCCACCCCTGCCGGGGAACGTGATG
ACCAGAGCCCAGACAGTGTCCCAGAGAGGCCACGGCCCGCAGACCGGAGGCTCTGTCTGCCCTG
CGTGGACGCCTCGCCACTCCCAGGGAGGACGGCCTGCCCGTCGCTGCAGGAGGCCACGCGCCTC
ATCCAGGAGGAATTTGCCTTCGATGGCTACCTGGACAATGGGCTGGAGGCTCTGATCATGGGGG
AGTACATCTTCGCCTTGAAAGATCTCACCTTTGCCACTTTCTGTGGCGCCATTTCCGAGAAGTT
CTGTGACCTGTACTGGGATGAGAAGTTGCTGCAGAACCTCTTTAAGGTGGTCAACGGGCAGGCG
TCACCCTCCCCAAGCACGGCGGAGGAGGCTGGGTCACAGCTCGAGGGCAGCCAAAGCCCCCGCT
CCCCGTCCAGCAAGAGGCCGTCGCTGCACCGCCTGGGAAAAGAGAAGCCAGCCGTGGCCAGGAC
CAGCAGCAGGGTCCCCTGCTCACCCACCTCGGTGTCGGATGTGGACTCGGACGCACTGTCACGG
GGAAACTTCGAGGTGGGGTTTCGGCCTCAGAGGTCCGTAAAAGCCGAGAGAGCGCAGCAGCCTG
AGGCTGGCGAGGACAGACGGCCAGCTGGCGGGGCCTCAGACATGGAGGCAGTGACCCGACTGGC
CAGGTCCAAGGGGGTCGGCCCAGCCTTGTCCCCCGGCCCAGCCGGATTCCAGAGCTGCAGCCCC
GGCTGGTGCAGCGCCTTCTACGAGGCCGACTGCTTCGGGGCCGACGTCCACAACTACGTGAAGG
ACCTGGGGTGGCAGCAGGTGGACGGGGCCCTGCCCGACGCCCAGAGCCCGGAGCTGGAACAGCA
GCTCATGATGGAGAAAAGAAACTACCGCAAGACCCTGAAATTCTACCAGAAACTCTTACAGAAG
GAAAAGAGGAACAAAGGTTCCGACGTCAAGACCATGCTGTCCAAGCTGAAAGGGCAGCTGGAAG
AAATGAAATCCAGGGTGCAATTCCTCAGCTTGGTCAAGAAGTATCTGCAGGTCATGTACGCGGA
ACGCTGGGGCCTGGAGCCCTGCGCCCTCCCGGTGATCGTGAACATCGCGGCCGCCCCCTGCGAC
ACGCTGGACTTCAGCCCCCTGGACGAGTCCTCCTCGCTCATCTTCTACAACGTCAACAAGCACC
CGGGCGGCCGGCAGAAGGCCCGCATCCTGCAGGCCGGCACGCCGCTGGGGCTCATGGCCTACCT
GTACTCCAGCGACGCCTTCCTGGAGGGCTACGTGCAGCAATTCCTCTACACCTTCCGCTACTTC
TGCACACCCCACGACTTCCTGCACTTCCTCCTCGACCGCATCAACAGCACGCTGACCAGGGCCC
ACCAGGACCCCACCTCGACCTTCACCAAGATCTACAGGCGGAGCCTCTGCGTCCTGCAGGCCTG
GGTGGAGGACTGCTACGCCGTGGACTTCTCTCGGAACAGCGGGCTGCTGGGGAAGCTAGAGGAC
TTCATCTCCTCCAAGATCCTACCCCTGGACGGCTCTGCCAAGCACCTGCTGGGCCTCCTGGAGG
TGGGCATGGACCGGCGGGCCGAGGGCAGCCCTCGCGGCACAGACCTGGAGAACCCCAGGGAGGC
CGAGGAGGATGCCAGACCCTTCAACGCCCTCTGTAAGAGGCTCTCAGAGGACGGCATCTCCAGG
AAGAGCTTCCCCTGGAGGCTGCCCCGAGGCAACGGGCTGGTGCTGCCGCCACACAAGGAGCGCC
CGTACACCATTGCCGCGGCCCTGCCCAAGCCCTGCTTCCTCGAGGACTTCTACGGCCCCTGCGC
CAAGACCAGTGAGAAGGGGCCCTACTTCCTGACGGAGTACAGCACTCACCAGCTCTTCAGCCAG
CTCACGCTGCTACAGCAGGAGTTGTTTCAAAAGTGCCACCCGGTCCACTTCCTGAACTCACGGG
CTCTGGGCGTCATGGACAAGAGCACTGCCATCCCCAAAGCCAGCTCTTCTGAGTCTCTTTCGGC
CAAAACCTGCAGCTTATTTCTGCCCAATTACGTTCAGGACAAGTATCTGTTACAGCTTCTAAGA
AACGCAGATGACGTCAGCACCTGGGTGGCTGCAGAGATTGTGACCAGCCACACCTCCAAGCTGC
AGGTGAACTTGCTGTCCAAATTCTTGCTGATTGCAAAATCTTGCTATGAGCAGAGAAACTTCGC
AACAGCCATGCAGATCCTGAGCGGGCTGGAGCACCTGGCCGTGAGGCAGTCCCCTGCCTGGAGA
ATTCTGCCTGCAAAGATAGCAGAGGTCATGGAGGAGCTGAAAGCCGTGGAGGTCTTCCTGAAGA
GCGACAGCCTGTGTCTGATGGAAGGTCGGCGCTTCCGGGCGCAGCCCACCCTGCCCTCGGCCCA
CCTCCTGGCCATGCACATCCAGCAGCTGGAGACAGGCGGCTTCACCATGACCAACGGGGCCCAC
AGGTGGAGCAAGCTCAGGAACATCGCGAAGGTGGTGAGCCAGGTGCACGCGTTCCAGGAGAACC
CTTACACCTTCAGCCCCGACCCCAAGCTCCAGTCGTACCTCAAGCAGAGGATTGCCCGCTTCAG
CGGTGCCGACATTTCCACACTCGCCGCAGATAGCAGGGCCAACTTCCACCAGGTCTCCAGCGAG
AAGCACTCACGGAAGATTCAGGACAAGCTACGGAGGATGAAGGCTACATTCCAGTAGCCGAGCT
CGGGCCTGGTGTGGAATTCCAGATCCGAATCCAACTGTGGGGGGCGGGCCGGGAGGTAGGAGCC
GCGTCTCAGGCCCGGCCGTTATCGAGGCCCCTCCGCCCCCGAACCCTGGGGAGCTGGACCAGGA
GGTGGAGGCTCAGGGGACCCCACGGGGACAGGCAGAGCTGGTCTCCTCCCAGCAGACGGAGCCA
GGACGGGCACAAGAGTCTTGGAGGTTTGCGTGTTTCTGCTAGAATTAAAAAGTTAAATTTAAAA
ATGAAAATGAAAG

hide sequence

RefSeq Acc Id:

XM_034951477 ⟹ XP_034807368

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	145,280,055 - 145,290,518 (+)	NCBI
NHGRI_mPanPan1	10	145,285,422 - 145,295,875 (+)	NCBI

RefSeq Acc Id:

XM_034951479 ⟹ XP_034807370

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	145,280,056 - 145,302,419 (+)	NCBI
NHGRI_mPanPan1	10	145,285,422 - 145,307,778 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_003816307	(Get FASTA)	NCBI Sequence Viewer
	XP_034807368	(Get FASTA)	NCBI Sequence Viewer
	XP_034807370	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000031745.1

RefSeq Acc Id:	XP_003816307 ⟸ XM_003816259
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9BQQ7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MQAMDPAAADLYEEDGKDLDFYDFEPLPTLPEDEENVSLADILSLRDRGLSEQEAWAVCLECSL SMRSVAHAAIFQSLCITPDTLAFNTSGNVCFMEQLSDDPEGAFVPPEFDVTGNTFEAHIYSLGA TLKAALEYVAEPTLEPRLSQDLEALLSRMQAEDPGDRPDLESIIALCEEKLQLTSSCRMCRSLS AVGRRVLSIESFGALQDVSESSWRERPAPGNAGPRRPPGDPSTDPEVLPTPEGPESETSRGPRA SPTKALLSTPVRNGESHSREGLAGLVLDAERTLGELDRDALRRSRLRKVQTFPRLLSDSPEATL CLPLTRGKSQLPMSELFSPDPRKAFLDRKNGLSSFQAQPKCRLWPEQEPEHQLGWVPCAGRSAD RGPGVPGSPGQPETSHPSQGPAEARPPPCPADPRDASGEAQTPRDDERIPEGARQLESAAAEQW VSLQELLSQLGRPFREYELWALCLACLRALQTRPEHPAYLCLDSVLVAEDGAVLFQPPPANGSY DSFFLAPELAEERLVTEKASVYCVAAVLWTAAKFSVPRNHKLALPRRLKTLLLDMARRSAPERP SAAEAIKVCGSYLLQRGMDSRKILAHLRASICQVYQEKETISLQNAFSVVELKPSVAPAPEPSP GFLPVNSDTGLVAVPGPVPSQHPCGEEATQLPAAFTSEATHFKPIVLAQDASVARDQPALAQEE SEERGGQREGEGEEKLSPEAHAGCPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPP QAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAEPILPGVASGGLRPDALGPTTAHHGPRH PPKPPRSKATERPGREPEGPGATPAGERDDQSPDSVPERPRPADRRLCLPCVDASPLPGRTACP SLQEATRLIQEEFAFDGYLDNGLEALIMGEYIFALKDLTFATFCGAISEKFCDLYWDEKLLQNL FKVVNGQASPSPSTAEEAGSQLEGSQSPRSPSSKRPSLHRLGKEKPAVARTSSRVPCSPTSVSD VDSDALSRGNFEVGFRPQRSVKAERAQQPEAGEDRRPAGGASDMEAVTRLARSKGVGPALSPGP AGFQSCSPGWCSAFYEADCFGADVHNYVKDLGWQQVDGALPDAQSPELEQQLMMEKRNYRKTLK FYQKLLQKEKRNKGSDVKTMLSKLKGQLEEMKSRVQFLSLVKKYLQVMYAERWGLEPCALPVIV NIAAAPCDTLDFSPLDESSSLIFYNVNKHPGGRQKARILQAGTPLGLMAYLYSSDAFLEGYVQQ FLYTFRYFCTPHDFLHFLLDRINSTLTRAHQDPTSTFTKIYRRSLCVLQAWVEDCYAVDFSRNS GLLGKLEDFISSKILPLDGSAKHLLGLLEVGMDRRAEGSPRGTDLENPREAEEDARPFNALCKR LSEDGISRKSFPWRLPRGNGLVLPPHKERPYTIAAALPKPCFLEDFYGPCAKTSEKGPYFLTEY STHQLFSQLTLLQQELFQKCHPVHFLNSRALGVMDKSTAIPKASSSESLSAKTCSLFLPNYVQD KYLLQLLRNADDVSTWVAAEIVTSHTSKLQVNLLSKFLLIAKSCYEQRNFATAMQILSGLEHLA VRQSPAWRILPAKIAEVMEELKAVEVFLKSDSLCLMEGRRFRAQPTLPSAHLLAMHIQQLETGG FTMTNGAHRWSKLRNIAKVVSQVHAFQENPYTFSPDPKLQSYLKQRIARFSGADISTLAADSRA NFHQVSSEKHSRKIQDKLRRMKATFQ hide sequence

Ensembl Acc Id:

ENSPPAP00000031745 ⟸ ENSPPAT00000054610

RefSeq Acc Id:	XP_034807370 ⟸ XM_034951479
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_034807368 ⟸ XM_034951477
- Peptide Label:	isoform X2

Protein Domains

KIND N-terminal Ras-GEF Ras-GEF

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000038779	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000054610.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.840.10	UniProtKB/TrEMBL
	Son of sevenless (SoS) protein Chain: S domain 1	UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	Kinase-like_dom_sf	UniProtKB/TrEMBL
	KIND_dom	UniProtKB/TrEMBL
	KNDC1	UniProtKB/TrEMBL
	Ras-like_Gua-exchang_fac_N	UniProtKB/TrEMBL
	Ras_GEF_dom_sf	UniProtKB/TrEMBL
	RASGEF_cat_dom	UniProtKB/TrEMBL
	RASGEF_cat_dom_sf	UniProtKB/TrEMBL
KEGG Report	pps:100993812	UniProtKB/TrEMBL
NCBI Gene	KNDC1	ENTREZGENE
PANTHER	KINASE NON-CATALYTIC C-LOBE DOMAIN-CONTAINING PROTEIN 1	UniProtKB/TrEMBL
	PTHR21560	UniProtKB/TrEMBL
Pfam	KIND	UniProtKB/TrEMBL
	RasGEF	UniProtKB/TrEMBL
	RasGEF_N	UniProtKB/TrEMBL
PROSITE	KIND	UniProtKB/TrEMBL
	RASGEF_CAT	UniProtKB/TrEMBL
	RASGEF_NTER	UniProtKB/TrEMBL
SMART	KIND	UniProtKB/TrEMBL
	RasGEF	UniProtKB/TrEMBL
	RasGEFN	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48366	UniProtKB/TrEMBL
	SSF56112	UniProtKB/TrEMBL
UniProt	A0A2R9BQQ7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2023-04-20	KNDC1	kinase non-catalytic C-lobe domain containing 1	LOC117977854	kinase non-catalytic C-lobe domain-containing protein 1-like	Data merged from RGD:32731980	737654	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar