IQGAP3 (IQ motif containing GTPase activating protein 3) - Rat Genome Database
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Gene: IQGAP3 (IQ motif containing GTPase activating protein 3) Pan paniscus
Analyze
Symbol: IQGAP3
Name: IQ motif containing GTPase activating protein 3
RGD ID: 11698383
Description: ENCODES a protein that exhibits calmodulin binding (ortholog); myosin VI light chain binding (ortholog); small GTPase binding (ortholog); INVOLVED IN activation of MAPK activity (ortholog); cellular response to organic substance (ortholog); ERK1 and ERK2 cascade (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cell-cell junction (ortholog); cytoplasm (ortholog); lateral plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: ras GTPase-activating-like protein IQGAP3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11135,695,602 - 135,740,564 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1135,695,602 - 135,740,564 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01131,869,002 - 131,916,554 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
IQGAP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11135,695,602 - 135,740,564 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1135,695,602 - 135,740,564 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01131,869,002 - 131,916,554 (-)NCBIMhudiblu_PPA_v0panPan3
IQGAP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1156,525,405 - 156,572,604 (-)EnsemblGRCh38hg38GRCh38
GRCh381156,525,405 - 156,572,605 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371156,495,197 - 156,542,357 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361154,761,821 - 154,809,020 (-)NCBINCBI36hg18NCBI36
Build 341153,308,270 - 153,355,469NCBI
Celera1129,568,222 - 129,613,182 (-)NCBI
Cytogenetic Map1q22NCBI
HuRef1127,855,158 - 127,900,121 (-)NCBIHuRef
CHM1_11157,891,665 - 157,938,571 (-)NCBICHM1_1
Iqgap3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39387,989,309 - 88,028,355 (+)NCBIGRCm39mm39
GRCm39 Ensembl387,989,278 - 88,028,355 (+)Ensembl
GRCm38388,082,002 - 88,121,048 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl388,081,971 - 88,121,048 (+)EnsemblGRCm38mm10GRCm38
MGSCv37387,885,973 - 87,924,970 (+)NCBIGRCm37mm9NCBIm37
MGSCv36388,167,927 - 88,206,975 (+)NCBImm8
Celera388,121,650 - 88,160,680 (+)NCBICelera
Cytogenetic Map3F1NCBI
cM Map338.78NCBI
Iqgap3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22173,542,151 - 173,583,956 (+)NCBI
Rnor_6.0 Ensembl2187,447,501 - 187,489,630 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02187,447,477 - 187,489,630 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02206,850,518 - 206,892,647 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42180,155,679 - 180,198,814 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12180,105,779 - 180,148,920 (+)NCBI
Celera2167,489,087 - 167,530,440 (+)NCBICelera
Cytogenetic Map2q34NCBI
Iqgap3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555452,628,552 - 2,663,737 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555452,627,334 - 2,663,786 (-)NCBIChiLan1.0ChiLan1.0
IQGAP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl741,382,994 - 41,419,742 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1741,384,539 - 41,420,529 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Iqgap3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365805,712,118 - 5,751,721 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IQGAP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl493,513,079 - 93,559,020 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1493,495,999 - 93,556,915 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24102,133,942 - 102,178,070 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IQGAP3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1207,286,819 - 7,334,352 (+)NCBI
ChlSab1.1 Ensembl207,286,886 - 7,333,284 (+)Ensembl
Iqgap3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248851,730,079 - 1,765,250 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000058387   ⟹   ENSPPAP00000035498
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1135,695,602 - 135,740,564 (-)Ensembl
RefSeq Acc Id: XM_003821051   ⟹   XP_003821099
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11135,695,602 - 135,740,564 (-)NCBI
Mhudiblu_PPA_v01131,869,002 - 131,916,554 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034937627   ⟹   XP_034793518
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v01131,869,002 - 131,916,554 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003821099 (Get FASTA)   NCBI Sequence Viewer  
  XP_034793518 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003821099   ⟸   XM_003821051
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_034793518   ⟸   XM_034937627
- Peptide Label: isoform X2
RefSeq Acc Id: ENSPPAP00000035498   ⟸   ENSPPAT00000058387
Protein Domains
Calponin-homology (CH)   Ras-GAP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040557 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000035498 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000058387 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.10 UniProtKB/TrEMBL
InterPro CH-domain UniProtKB/TrEMBL
  CH_dom_sf UniProtKB/TrEMBL
  IQ_motif_EF-hand-BS UniProtKB/TrEMBL
  RasGAP_C UniProtKB/TrEMBL
  RasGAP_CS UniProtKB/TrEMBL
  RasGAP_dom UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
KEGG Report pps:100974131 UniProtKB/TrEMBL
NCBI Gene IQGAP3 ENTREZGENE
Pfam PF00307 UniProtKB/TrEMBL
  PF00612 UniProtKB/TrEMBL
  RasGAP UniProtKB/TrEMBL
  RasGAP_C UniProtKB/TrEMBL
PROSITE PS50021 UniProtKB/TrEMBL
  PS50096 UniProtKB/TrEMBL
  RAS_GTPASE_ACTIV_1 UniProtKB/TrEMBL
  RAS_GTPASE_ACTIV_2 UniProtKB/TrEMBL
SMART RasGAP UniProtKB/TrEMBL
  SM00015 UniProtKB/TrEMBL
  SM00033 UniProtKB/TrEMBL
Superfamily-SCOP SSF47576 UniProtKB/TrEMBL
  SSF48350 UniProtKB/TrEMBL
UniProt A0A2R9C0Q3_PANPA UniProtKB/TrEMBL