IQGAP3 (IQ motif containing GTPase activating protein 3) - Rat Genome Database
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Gene: IQGAP3 (IQ motif containing GTPase activating protein 3) Pan paniscus
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Symbol: IQGAP3
Name: IQ motif containing GTPase activating protein 3
RGD ID: 11698383
Description: ENCODES a protein that exhibits calmodulin binding (ortholog); myosin VI light chain binding (ortholog); small GTPase binding (ortholog); INVOLVED IN activation of MAPK activity (ortholog); cellular response to organic substance (ortholog); ERK1 and ERK2 cascade (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cell-cell junction (ortholog); cytoplasm (ortholog); lateral plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: ras GTPase-activating-like protein IQGAP3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11135,695,602 - 135,740,564 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1135,695,602 - 135,740,564 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01131,869,002 - 131,916,554 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

Genomics

Comparative Map Data
IQGAP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11135,695,602 - 135,740,564 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1135,695,602 - 135,740,564 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01131,869,002 - 131,916,554 (-)NCBIMhudiblu_PPA_v0panPan3
IQGAP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1156,525,405 - 156,572,604 (-)EnsemblGRCh38hg38GRCh38
GRCh381156,525,405 - 156,572,605 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371156,495,197 - 156,542,357 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361154,761,821 - 154,809,020 (-)NCBINCBI36hg18NCBI36
Build 341153,308,270 - 153,355,469NCBI
Celera1129,568,222 - 129,613,182 (-)NCBI
Cytogenetic Map1q22NCBI
HuRef1127,855,158 - 127,900,121 (-)NCBIHuRef
CHM1_11157,891,665 - 157,938,571 (-)NCBICHM1_1
Iqgap3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39387,989,309 - 88,028,355 (+)NCBIGRCm39mm39
GRCm39 Ensembl387,989,278 - 88,028,355 (+)Ensembl
GRCm38388,082,002 - 88,121,048 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl388,081,971 - 88,121,048 (+)EnsemblGRCm38mm10GRCm38
MGSCv37387,885,973 - 87,924,970 (+)NCBIGRCm37mm9NCBIm37
MGSCv36388,167,927 - 88,206,975 (+)NCBImm8
Celera388,121,650 - 88,160,680 (+)NCBICelera
Cytogenetic Map3F1NCBI
cM Map338.78NCBI
Iqgap3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22173,542,151 - 173,583,956 (+)NCBI
Rnor_6.0 Ensembl2187,447,501 - 187,489,630 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02187,447,477 - 187,489,630 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02206,850,518 - 206,892,647 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42180,155,679 - 180,198,814 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12180,105,779 - 180,148,920 (+)NCBI
Celera2167,489,087 - 167,530,440 (+)NCBICelera
Cytogenetic Map2q34NCBI
Iqgap3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555452,628,552 - 2,663,737 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555452,627,334 - 2,663,786 (-)NCBIChiLan1.0ChiLan1.0
IQGAP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl741,382,994 - 41,419,742 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1741,384,539 - 41,420,529 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Iqgap3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365805,712,118 - 5,751,721 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IQGAP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl493,513,079 - 93,559,020 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1493,495,999 - 93,556,915 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24102,133,942 - 102,178,070 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IQGAP3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1207,286,819 - 7,334,352 (+)NCBI
ChlSab1.1 Ensembl207,286,886 - 7,333,284 (+)Ensembl
Iqgap3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248851,730,079 - 1,765,250 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000058387   ⟹   ENSPPAP00000035498
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1135,695,602 - 135,740,564 (-)Ensembl
RefSeq Acc Id: XM_003821051   ⟹   XP_003821099
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11135,695,602 - 135,740,564 (-)NCBI
Mhudiblu_PPA_v01131,869,002 - 131,916,554 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034937627   ⟹   XP_034793518
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v01131,869,002 - 131,916,554 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003821099 (Get FASTA)   NCBI Sequence Viewer  
  XP_034793518 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003821099   ⟸   XM_003821051
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_034793518   ⟸   XM_034937627
- Peptide Label: isoform X2
RefSeq Acc Id: ENSPPAP00000035498   ⟸   ENSPPAT00000058387
Protein Domains
Calponin-homology (CH)   Ras-GAP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040557 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000035498 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000058387 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.10 UniProtKB/TrEMBL
InterPro CH-domain UniProtKB/TrEMBL
  CH_dom_sf UniProtKB/TrEMBL
  IQ_motif_EF-hand-BS UniProtKB/TrEMBL
  RasGAP_C UniProtKB/TrEMBL
  RasGAP_CS UniProtKB/TrEMBL
  RasGAP_dom UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
KEGG Report pps:100974131 UniProtKB/TrEMBL
NCBI Gene IQGAP3 ENTREZGENE
Pfam PF00307 UniProtKB/TrEMBL
  PF00612 UniProtKB/TrEMBL
  RasGAP UniProtKB/TrEMBL
  RasGAP_C UniProtKB/TrEMBL
PROSITE PS50021 UniProtKB/TrEMBL
  PS50096 UniProtKB/TrEMBL
  RAS_GTPASE_ACTIV_1 UniProtKB/TrEMBL
  RAS_GTPASE_ACTIV_2 UniProtKB/TrEMBL
SMART RasGAP UniProtKB/TrEMBL
  SM00015 UniProtKB/TrEMBL
  SM00033 UniProtKB/TrEMBL
Superfamily-SCOP SSF47576 UniProtKB/TrEMBL
  SSF48350 UniProtKB/TrEMBL
UniProt A0A2R9C0Q3_PANPA UniProtKB/TrEMBL