YWHAQ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta) - Rat Genome Database

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Gene: YWHAQ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta) Pan paniscus
Analyze
Symbol: YWHAQ
Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
RGD ID: 12031429
Description: ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); protein domain specific binding (ortholog); transmembrane transporter binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); negative regulation of monoatomic ion transmembrane transport (ortholog); protein targeting (ortholog); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; mTOR signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH NEURODEVELOPMENTAL DISORDER WITH MICROCEPHALY, HYPOTONIA, NYSTAGMUS, AND SEIZURES (ortholog); osteoarthritis (ortholog); FOUND IN nucleus (ortholog); protein-containing complex (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 14-3-3 protein theta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212116,895,271 - 116,943,104 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A116,899,244 - 116,946,787 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A9,573,413 - 9,620,495 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A9,735,448 - 9,772,074 (-)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
YWHAQ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212116,895,271 - 116,943,104 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A116,899,244 - 116,946,787 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A9,573,413 - 9,620,495 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A9,735,448 - 9,772,074 (-)NCBIpanpan1.1PanPan1.1panPan2
YWHAQ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3829,583,967 - 9,630,997 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl29,583,967 - 9,630,997 (-)EnsemblGRCh38hg38GRCh38
GRCh3729,724,096 - 9,771,126 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3629,641,557 - 9,688,557 (-)NCBINCBI36Build 36hg18NCBI36
Build 3429,674,703 - 9,721,704NCBI
Celera29,635,980 - 9,682,954 (-)NCBICelera
Cytogenetic Map2p25.1NCBI
HuRef29,569,609 - 9,616,664 (-)NCBIHuRef
CHM1_129,653,476 - 9,700,564 (-)NCBICHM1_1
T2T-CHM13v2.029,609,000 - 9,656,011 (-)NCBIT2T-CHM13v2.0
Ywhaq
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391221,440,330 - 21,467,437 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1221,440,072 - 21,467,638 (-)EnsemblGRCm39 Ensembl
GRCm381221,390,329 - 21,417,436 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1221,390,071 - 21,417,637 (-)EnsemblGRCm38mm10GRCm38
MGSCv371221,396,190 - 21,423,297 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361221,636,819 - 21,663,926 (-)NCBIMGSCv36mm8
Celera1219,483,848 - 19,511,370 (+)NCBICelera
Cytogenetic Map12A1.3NCBI
cM Map128.31NCBI
Ywhaq
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8646,664,358 - 46,694,875 (-)NCBIGRCr8
mRatBN7.2640,935,714 - 40,966,240 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl640,935,949 - 40,966,273 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx641,257,806 - 41,288,261 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0641,572,495 - 41,602,946 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0641,005,763 - 41,036,210 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0643,463,294 - 43,493,816 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl643,463,294 - 43,493,816 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0660,331,003 - 60,361,242 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4641,945,769 - 41,976,123 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1641,948,894 - 41,979,249 (-)NCBI
Celera640,222,774 - 40,252,668 (-)NCBICelera
Cytogenetic Map6q16NCBI
Ywhaq
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554875,230,506 - 5,263,752 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554875,229,485 - 5,263,749 (-)NCBIChiLan1.0ChiLan1.0
YWHAQ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1176,660,504 - 6,697,954 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha176,588,178 - 6,625,624 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0176,759,032 - 6,796,562 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl176,758,751 - 6,796,522 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1176,651,427 - 6,688,863 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0176,653,706 - 6,691,132 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0176,667,564 - 6,705,013 (-)NCBIUU_Cfam_GSD_1.0
Ywhaq
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629251,176,636 - 51,199,301 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365325,931,677 - 5,938,569 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
YWHAQ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3126,738,862 - 126,772,778 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13126,738,795 - 126,772,784 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23135,245,481 - 135,278,697 (-)NCBISscrofa10.2Sscrofa10.2susScr3
YWHAQ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11498,017,300 - 98,064,973 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604514,257,939 - 14,305,505 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ywhaq
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624969167,676 - 199,963 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624969167,635 - 199,963 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_034952591   ⟹   XP_034808482
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v212116,895,271 - 116,943,104 (+)NCBI
NHGRI_mPanPan12A116,899,244 - 116,946,787 (+)NCBI
Mhudiblu_PPA_v02A9,573,413 - 9,620,495 (-)NCBI
RefSeq Acc Id: XM_063595054   ⟹   XP_063451124
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v212116,896,119 - 116,943,104 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034808482 (Get FASTA)   NCBI Sequence Viewer  
  XP_063451124 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000040764.1
RefSeq Acc Id: XP_034808482   ⟸   XM_034952591
RefSeq Acc Id: XP_063451124   ⟸   XM_063595054
Protein Domains
14-3-3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043019 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000063683.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.190.20 UniProtKB/TrEMBL
InterPro 14-3-3 UniProtKB/TrEMBL
  14-3-3_CS UniProtKB/TrEMBL
  14-3-3_dom_sf UniProtKB/TrEMBL
  14-3-3_domain UniProtKB/TrEMBL
NCBI Gene YWHAQ ENTREZGENE
PANTHER 14-3-3 PROTEIN THETA UniProtKB/TrEMBL
  PTHR18860 UniProtKB/TrEMBL
Pfam 14-3-3 UniProtKB/TrEMBL
PRINTS 1433ZETA UniProtKB/TrEMBL
PROSITE 1433_2 UniProtKB/TrEMBL
SMART 14_3_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF48445 UniProtKB/TrEMBL
UniProt A0A2R9CFU0_PANPA UniProtKB/TrEMBL