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ONTOLOGY REPORT - ANNOTATIONS

Term:activation of innate immune response
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Accession:GO:0002218 term browser browse the term
Definition:Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species.
Synonyms:alt_id: GO:0002219


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activation of innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP6 caspase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:112,519,450...112,534,315
Ensembl chr 8:112,520,629...112,537,045 		JBrowse link
G CGAS cyclic GMP-AMP synthase involved_in ISS
IEA
IBA		 UniProt
Ensembl
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:92,483,253...92,500,376
Ensembl chr 1:92,483,327...92,504,307 		JBrowse link
G GBP1 guanylate binding protein 1, interferon-inducible involved_in ISO (PMID:24739961) UniProt PMID:24739961 NCBI chr 4:127,425,699...127,442,132
Ensembl chr 4:127,425,200...127,442,127 		JBrowse link
G GBP2 guanylate binding protein 2, interferon-inducible involved_in ISO (PMID:24739961) UniProt PMID:24739961 NCBI chr 4:127,387,222...127,408,729
Ensembl chr 4:127,379,740...127,408,699 		JBrowse link
G HEXIM1 HEXIM P-TEFb complex subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:18,267,023...18,270,089
Ensembl chr12:18,267,027...18,269,165 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:24971542) UniProt PMID:24971542 NCBI chr11:7,195,556...7,321,071 JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:67,123,055...67,147,991
Ensembl chr 9:67,123,265...67,147,989 		JBrowse link
G LOC100155195 guanylate-binding protein 7 involved_in ISO (PMID:24739961) UniProt PMID:24739961 NCBI chr 4:127,356,794...127,376,858 JBrowse link
G LOC733579 tripartite motif protein TRIM5 involved_in ISO (PMID:21512573) UniProt PMID:21512573 NCBI chr 9:4,157,290...4,170,233
Ensembl chr 9:4,157,290...4,170,204 		JBrowse link
G MATR3 matrin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:141,179,515...141,230,259
Ensembl chr 2:141,179,566...141,231,015 		JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:31,850,646...31,869,273
Ensembl chr17:31,850,900...31,869,188 		JBrowse link
G MNDA myeloid cell nuclear differentiation antigen involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 Ensembl chr 4:91,416,432...91,433,242 JBrowse link
G NLRC4 NLR family CARD domain containing 4 involved_in ISO (PMID:16648852) UniProt PMID:16648852 NCBI chr 3:107,358,117...107,389,557 JBrowse link
G NONO non-POU domain containing octamer binding involved_in IEA Ensembl GO_REF:0000107 Ensembl chr  X:57,278,915...57,316,224 JBrowse link
G PQBP1 polyglutamine binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:42,976,086...42,981,732
Ensembl chr  X:42,975,413...42,981,724 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:79,687,375...79,850,146
Ensembl chr 4:79,687,375...79,846,656 		JBrowse link
G PRPS2 phosphoribosyl pyrophosphate synthetase 2 involved_in IEA UniProt GO_REF:0000117 NCBI chr  X:9,505,034...9,531,044
Ensembl chr  X:9,503,953...9,530,086 		JBrowse link
G PSPC1 paraspeckle component 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:477,010...572,090
Ensembl chr11:482,564...572,090 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:17,305,921...17,307,521
Ensembl chr 3:17,306,099...17,307,786 		JBrowse link
G RBM14 RNA binding motif protein 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:5,791,445...5,800,784
Ensembl chr 2:5,759,098...5,800,748 		JBrowse link
G SFPQ splicing factor proline and glutamine rich involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:91,391,552...91,408,236
Ensembl chr 6:91,391,555...91,408,219 		JBrowse link
G SIN3A SIN3 transcription regulator family member A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:58,171,821...58,246,126
Ensembl chr 7:58,176,167...58,245,971 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:141,359,402...141,367,222
Ensembl chr 2:141,358,993...141,367,198 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15661922) Ensembl
MGI		 PMID:15661922 GO_REF:0000107 NCBI chr 5:28,880,210...28,929,964
Ensembl chr 5:28,880,205...28,929,963 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15661922) Ensembl
MGI		 PMID:15661922 GO_REF:0000107 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
G TLR7 toll like receptor 7 involved_in IEA UniProt GO_REF:0000117 NCBI chr  X:9,573,178...9,576,987 JBrowse link
G TLR9 toll like receptor 9 involved_in IEA UniProt
Ensembl		 GO_REF:0000107 GO_REF:0000117 NCBI chr13:34,353,444...34,370,990
Ensembl chr13:34,349,609...34,357,673 		JBrowse link
G TMEM169 transmembrane protein 169 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:118,335,915...118,352,713
Ensembl chr15:118,346,943...118,352,707 		JBrowse link
G TOMM70 translocase of outer mitochondrial membrane 70 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:158,577,026...158,629,878
Ensembl chr13:158,577,379...158,628,262 		JBrowse link
G XRCC5 X-ray repair cross complementing 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:118,354,943...118,451,974
Ensembl chr15:118,354,796...118,451,960 		JBrowse link
G XRCC6 X-ray repair cross complementing 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:6,903,496...6,929,162
Ensembl chr 5:6,903,495...6,929,052 		JBrowse link
G ZBP1 Z-DNA binding protein 1 involved_in ISO (PMID:32350114), (PMID:33109609)
(PMID:32200799), (PMID:32296175)		 UniProt PMID:32200799 PMID:32296175 PMID:32350114 PMID:33109609 NCBI chr17:57,975,982...57,986,117
Ensembl chr17:57,973,096...57,986,136 		JBrowse link
G ZCCHC3 zinc finger CCHC-type containing 3 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr17:34,882,812...34,885,632
Ensembl chr17:34,882,816...34,885,505 		JBrowse link
G ZNFX1 zinc finger NFX1-type containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:50,925,789...50,958,722
Ensembl chr17:50,925,791...50,958,705 		JBrowse link
cell surface pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:142,348,036...142,349,686
Ensembl chr 2:142,346,360...142,349,581 		JBrowse link
G CLEC7A C-type lectin domain containing 7A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12719478) MGI
Ensembl		 PMID:12719478 GO_REF:0000107 NCBI chr 5:61,832,910...61,846,441
Ensembl chr 5:61,832,954...61,846,434 		JBrowse link
G FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) involved_in ISO (PMID:21037097) UniProt PMID:21037097 NCBI chr 1:274,106,276...274,111,970
Ensembl chr 1:274,103,877...274,111,970 		JBrowse link
G FFAR2 free fatty acid receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:44,899,879...44,904,461
Ensembl chr 6:44,901,159...44,904,459 		JBrowse link
G LBP lipopolysaccharide binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:41,398,935...41,429,467
Ensembl chr17:41,393,818...41,429,551 		JBrowse link
G MBL2 mannose binding lectin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:97,103,926...97,107,635
Ensembl chr14:97,102,823...97,108,083 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:2,103,706...2,160,886
Ensembl chr14:2,056,670...2,161,171 		JBrowse link
G TLR2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:12719478) MGI PMID:12719478 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,993...75,428,330 		JBrowse link
cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CGAS cyclic GMP-AMP synthase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:92,483,253...92,500,376
Ensembl chr 1:92,483,327...92,504,307 		JBrowse link
G DDX41 DEAD-box helicase 41 involved_in ISO (PMID:35613581) UniProt PMID:35613581 NCBI chr 2:80,433,065...80,445,484
Ensembl chr 2:80,433,190...80,438,867 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:141,359,402...141,367,222
Ensembl chr 2:141,358,993...141,367,198 		JBrowse link
cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALPK1 alpha kinase 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:110,241,220...110,368,001
Ensembl chr 8:110,241,619...110,367,912 		JBrowse link
G BECN1 beclin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373 		JBrowse link
G CGAS cyclic GMP-AMP synthase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:92,483,253...92,500,376
Ensembl chr 1:92,483,327...92,504,307 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr12:20,647,698...20,656,691
Ensembl chr12:20,647,699...20,656,683 		JBrowse link
G IPO5 importin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:67,019,299...67,059,375
Ensembl chr11:67,004,109...67,060,551 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:54,701,733...54,706,079
Ensembl chr 6:54,701,668...54,707,151 		JBrowse link
G IRF7 interferon regulatory factor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:372,235...375,572
Ensembl chr 2:372,238...375,378 		JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:31,850,646...31,869,273
Ensembl chr17:31,850,900...31,869,188 		JBrowse link
G RIGI RNA sensor RIG-I involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr10:33,891,720...33,976,151
Ensembl chr10:33,891,763...33,933,455 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:141,359,402...141,367,222
Ensembl chr 2:141,358,993...141,367,198 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:28,880,210...28,929,964
Ensembl chr 5:28,880,205...28,929,963 		JBrowse link
G TIFA TRAF interacting protein with forkhead associated domain involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:110,377,817...110,394,190
Ensembl chr 8:110,377,892...110,389,604 		JBrowse link
G TRAF3IP3 TRAF3 interacting protein 3 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:133,190,020...133,214,209
Ensembl chr 9:133,190,014...133,214,207 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:24,602,749...24,628,263
Ensembl chr 2:24,602,804...24,626,072 		JBrowse link
G TRIM25 tripartite motif containing 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:33,184,039...33,212,440
Ensembl chr12:33,184,049...33,212,398 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:47,601,133...47,645,327
Ensembl chr12:47,600,745...47,645,301 		JBrowse link
endolysosomal toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WASHC4 WASH complex subunit 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:33749590) MGI
Ensembl		 PMID:33749590 GO_REF:0000107 NCBI chr 5:79,417,119...79,474,655
Ensembl chr 5:79,417,130...79,474,609 		JBrowse link
inflammasome-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ELP6 elongator acetyltransferase complex subunit 6 acts_upstream_of_or_within ISO (PMID:30097576) MGI PMID:30097576 NCBI chr13:30,329,815...30,341,952
Ensembl chr13:30,325,249...30,341,295 		JBrowse link
innate immune response-activating signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TLR4 toll like receptor 4 ISO RGD PMID:19226379 RGD:2312509 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFIH1 interferon induced with helicase C domain 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr15:68,930,998...68,985,145
Ensembl chr15:68,928,254...68,985,083 		JBrowse link
MyD88-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRFIP2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) MGI PMID:19265123 NCBI chr13:21,666,896...21,790,352
Ensembl chr13:21,670,424...21,793,043 		JBrowse link
MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB1 high mobility group box 1 involved_in IDA (PMID:14660645) UniProt PMID:14660645 NCBI chr11:7,195,556...7,321,071 JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:101,360,355...101,373,498
Ensembl chr15:101,360,094...101,373,526 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12872135)
(PMID:12719478)
(PMID:14764662)		 InterPro
MGI
Ensembl		 PMID:12719478 PMID:12872135 PMID:14764662 GO_REF:0000002 GO_REF:0000107 NCBI chr13:22,976,951...22,979,568
Ensembl chr13:22,966,137...22,983,109 		JBrowse link
G TLR2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:12719478) MGI PMID:12719478 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,993...75,428,330 		JBrowse link
G TLR4 toll like receptor 4 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
G TLR6 toll like receptor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:30,159,744...30,180,650
Ensembl chr 8:30,159,754...30,180,650 		JBrowse link
G TLR9 toll like receptor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:34,353,444...34,370,990
Ensembl chr13:34,349,609...34,357,673 		JBrowse link
G TNIP1 TNFAIP3 interacting protein 1 involved_in ISO (PMID:22011580) UniProt PMID:22011580 NCBI chr16:71,926,038...71,979,969
Ensembl chr16:71,926,133...71,979,966 		JBrowse link
MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRFIP2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) MGI PMID:19265123 NCBI chr13:21,666,896...21,790,352
Ensembl chr13:21,670,424...21,793,043 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12855817)
(PMID:12872135)		 Ensembl
MGI		 PMID:12855817 PMID:12872135 GO_REF:0000107 NCBI chr 2:74,004,566...74,021,100
Ensembl chr 2:74,004,308...74,021,873 		JBrowse link
G TNIP3 TNFAIP3 interacting protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:102,892,427...102,990,902
Ensembl chr 8:102,892,366...102,991,848 		JBrowse link
negative regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRIM11 tripartite motif containing 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:51,729,333...51,743,256
Ensembl chr 2:51,733,181...51,743,254 		JBrowse link
negative regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AARS2 alanyl-tRNA synthetase 2, mitochondrial involved_in ISO (PMID:39322678) UniProt PMID:39322678 NCBI chr 7:39,301,020...39,314,296
Ensembl chr 7:39,301,009...39,313,860 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 involved_in ISO (PMID:26440888) UniProt PMID:26440888
G AURKB aurora kinase B involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:53,410,833...53,426,165
Ensembl chr12:53,410,177...53,423,225 		JBrowse link
G BANF1 BAF nuclear assembly factor 1 involved_in ISO (PMID:32792394) UniProt PMID:32792394 NCBI chr 2:6,333,451...6,335,326
Ensembl chr 2:6,333,453...6,334,839 		JBrowse link
G CGAS cyclic GMP-AMP synthase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:92,483,253...92,500,376
Ensembl chr 1:92,483,327...92,504,307 		JBrowse link
G LYPLAL1 lysophospholipase like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:8,946,463...9,061,033
Ensembl chr10:8,946,487...9,062,412 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:14,203,157...14,241,164
Ensembl chr10:14,203,160...14,241,196 		JBrowse link
G PCBP2 poly(rC) binding protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:18,670,124...18,703,745
Ensembl chr 5:18,673,981...18,704,978 		JBrowse link
G PPP6C protein phosphatase 6 catalytic subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:265,872,961...265,898,146
Ensembl chr 1:265,870,477...265,898,124 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:79,687,375...79,850,146
Ensembl chr 4:79,687,375...79,846,656 		JBrowse link
G SMPDL3A sphingomyelin phosphodiesterase acid like 3A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:39,848,641...39,869,184
Ensembl chr 1:39,848,648...39,868,731 		JBrowse link
G SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:40,184,534...40,190,519
Ensembl chr 3:40,185,014...40,190,518 		JBrowse link
G TREX1 three prime repair exonuclease 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:31,177,604...31,180,764
Ensembl chr13:31,179,291...31,180,747 		JBrowse link
G ZDHHC18 zinc finger DHHC-type palmitoyltransferase 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:84,153,854...84,183,772
Ensembl chr 6:84,153,838...84,182,305 		JBrowse link
negative regulation of cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITCH itchy E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:37,810,113...37,918,963
Ensembl chr17:37,810,235...37,918,209 		JBrowse link
G LOC100739719 tetraspanin-6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:82,375,028...82,376,050 JBrowse link
G TARBP2 TARBP2 subunit of RISC loading complex involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:18,718,588...18,723,843
Ensembl chr 5:18,718,688...18,723,839 		JBrowse link
G TAX1BP1 Tax1 binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:44,827,908...44,910,265
Ensembl chr18:44,827,095...44,910,235 		JBrowse link
G TSPAN6 tetraspanin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:82,323,634...82,328,919
Ensembl chr  X:82,323,624...82,328,903 		JBrowse link
negative regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QBP complement C1q binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:51,548,361...51,553,076
Ensembl chr12:51,548,415...51,555,689 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:20,647,698...20,656,691
Ensembl chr12:20,647,699...20,656,683 		JBrowse link
G RIOK3 RIO kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:108,338,986...108,363,872
Ensembl chr 6:108,339,013...108,363,868 		JBrowse link
G TKFC triokinase and FMN cyclase involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:10,158,183...10,171,452
Ensembl chr 2:10,158,188...10,171,449 		JBrowse link
negative regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD300A CD300a molecule involved_in ISO (PMID:22043923) UniProt PMID:22043923 NCBI chr12:6,665,578...6,681,329 JBrowse link
G CD300LF CD300 molecule like family member f involved_in ISO (PMID:22043923) UniProt PMID:22043923 NCBI chr12:6,501,151...6,521,135 JBrowse link
negative regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SARM1 sterile alpha and TIR motif containing 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr12:44,654,364...44,676,942
Ensembl chr12:44,655,811...44,676,945 		JBrowse link
negative regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABHD17A abhydrolase domain containing 17A, depalmitoylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:76,658,073...76,666,561
Ensembl chr 2:76,658,068...76,666,552 		JBrowse link
G CPTP ceramide-1-phosphate transfer protein involved_in ISO (PMID:29164996) UniProt PMID:29164996 NCBI chr 6:63,607,991...63,612,325 JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 involved_in ISO (PMID:34615873) UniProt PMID:34615873 NCBI chr 2:150,612,845...150,662,431
Ensembl chr 2:150,612,077...150,662,284 		JBrowse link
G FBXL2 F-box and leucine rich repeat protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:19,128,145...19,206,458
Ensembl chr13:19,128,237...19,221,201 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:49,982,278...49,986,760
Ensembl chr 9:49,982,284...49,990,508 		JBrowse link
G LAMP2 lysosomal associated membrane protein 2 involved_in ISO (PMID:36586411) UniProt PMID:36586411 NCBI chr  X:98,586,718...98,623,939
Ensembl chr  X:98,556,710...98,623,940 		JBrowse link
G MEFV MEFV innate immunity regulator, pyrin involved_in ISO (PMID:26347139) UniProt PMID:26347139 NCBI chr 3:38,934,573...38,948,609 JBrowse link
G NLRC3 NLR family CARD domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:38,673,590...38,719,188
Ensembl chr 3:38,687,967...38,710,938 		JBrowse link
G SIRT2 sirtuin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23502856) Ensembl
MGI		 PMID:23502856 GO_REF:0000107 NCBI chr 6:47,682,427...47,703,408
Ensembl chr 6:47,682,429...47,703,384 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:32514138)
(PMID:29887864)		 ARUK-UCL
Ensembl		 PMID:29887864 PMID:32514138 GO_REF:0000107 NCBI chr 7:36,465,921...36,471,509
Ensembl chr 7:36,465,324...36,471,516 		JBrowse link
G TRIM31 tripartite motif containing 31 involved_in ISO (PMID:27929086) UniProt PMID:27929086 NCBI chr 7:22,665,150...22,681,616 JBrowse link
G ZDHHC12 zinc finger DHHC-type palmitoyltransferase 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:269,081,274...269,084,853
Ensembl chr 1:269,081,272...269,084,840 		JBrowse link
G ZER1 zyg-11 related cell cycle regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:269,088,696...269,121,895
Ensembl chr 1:269,090,159...269,108,256 		JBrowse link
negative regulation of non-canonical inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:57,521,091...57,558,467
Ensembl chr  X:57,521,098...57,558,515 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:26,474,158...26,489,771
Ensembl chr 1:26,473,938...26,489,822 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERBIN erbb2 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:44,415,106...44,533,353
Ensembl chr16:44,415,189...44,533,349 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:106,692,102...106,758,101
Ensembl chr 4:106,686,604...106,758,099 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:26,474,158...26,489,771
Ensembl chr 1:26,473,938...26,489,822 		JBrowse link
G ZNRF4 zinc and ring finger 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:73,484,904...73,486,349
Ensembl chr 2:73,481,337...73,486,347 		JBrowse link
negative regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QBP complement C1q binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:51,548,361...51,553,076
Ensembl chr12:51,548,415...51,555,689 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr12:20,647,698...20,656,691
Ensembl chr12:20,647,699...20,656,683 		JBrowse link
G GPATCH3 G-patch domain containing 3 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 6:84,200,727...84,218,710
Ensembl chr 6:84,209,809...84,218,701 		JBrowse link
G NLRX1 NLR family member X1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21703540) Ensembl
MGI		 PMID:21703540 GO_REF:0000107 NCBI chr 9:46,384,373...46,400,752
Ensembl chr 9:46,384,948...46,400,983 		JBrowse link
G NPLOC4 NPL4 homolog, ubiquitin recognition factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,251,377...1,285,668
Ensembl chr12:1,251,053...1,285,666 		JBrowse link
G RNF125 ring finger protein 125 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:115,857,697...115,905,550
Ensembl chr 6:115,857,721...115,903,677 		JBrowse link
G SEC14L1 SEC14 like lipid binding 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr12:4,439,045...4,489,078
Ensembl chr12:4,441,114...4,489,081 		JBrowse link
G UFD1 ubiquitin recognition factor in ER associated degradation 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:51,113,858...51,132,820
Ensembl chr14:51,113,713...51,133,072 		JBrowse link
negative regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 involved_in ISO (PMID:23609450) UniProt PMID:23609450 NCBI chr11:49,077,152...49,088,218
Ensembl chr11:49,077,492...49,087,104 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:75,793,273...75,903,710
Ensembl chr 4:75,793,492...75,903,496 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:56,200,455...56,296,151
Ensembl chr15:56,200,455...56,295,064 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15220916) Ensembl
MGI		 PMID:15220916 GO_REF:0000107 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534 		JBrowse link
G TLR6 toll like receptor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:30,159,744...30,180,650
Ensembl chr 8:30,159,754...30,180,650 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31134514) ARUK-UCL PMID:31134514 NCBI chr 7:36,465,921...36,471,509
Ensembl chr 7:36,465,324...36,471,516 		JBrowse link
negative regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:85,732,082...85,747,552
Ensembl chr 2:85,732,189...85,750,858 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:26,474,158...26,489,771
Ensembl chr 1:26,473,938...26,489,822 		JBrowse link
G UBQLN1 ubiquilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:31,275,916...31,317,521
Ensembl chr10:31,275,868...31,317,516 		JBrowse link
negative regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 involved_in ISO (PMID:23609450) UniProt PMID:23609450 NCBI chr11:49,077,152...49,088,218
Ensembl chr11:49,077,492...49,087,104 		JBrowse link
G BPIFB1 BPI fold containing family B member 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr17:36,782,307...36,809,756
Ensembl chr17:36,782,307...36,809,754 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:261,732,280...261,859,833
Ensembl chr 1:261,659,660...261,859,022 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:75,793,273...75,903,710
Ensembl chr 4:75,793,492...75,903,496 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:56,200,455...56,296,151
Ensembl chr15:56,200,455...56,295,064 		JBrowse link
G MIR140 microRNA mir-140 involved_in ISO (PMID:30233718)
(PMID:30321456)		 ARUK-UCL PMID:30233718 PMID:30321456 NCBI chr 6:17,077,530...17,077,599
Ensembl chr 6:17,077,507...17,077,620 		JBrowse link
G MIR20A microRNA mir-20a involved_in ISO (PMID:29653364) ARUK-UCL PMID:29653364 NCBI chr11:60,735,109...60,735,179
Ensembl chr11:60,735,099...60,735,196 		JBrowse link
G MIR708 microRNA mir-708 involved_in ISO (PMID:31599428) ARUK-UCL PMID:31599428 NCBI chr 9:13,780,171...13,780,250
Ensembl chr 9:13,780,171...13,780,250 		JBrowse link
G NR1D1 nuclear receptor subfamily 1 group D member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:22,263,549...22,274,131
Ensembl chr12:22,263,657...22,271,643 		JBrowse link
G RAB7B RAB7B, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:66,635,636...66,666,034
Ensembl chr 9:66,635,638...66,666,036 		JBrowse link
G SQSTM1 sequestosome 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:78,752,768...78,763,998
Ensembl chr 2:78,752,771...78,763,938 		JBrowse link
G TAX1BP1 Tax1 binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:44,827,908...44,910,265
Ensembl chr18:44,827,095...44,910,235 		JBrowse link
G TICAM2 toll like receptor adaptor molecule 2 involved_in ISO (PMID:19412184) UniProt PMID:19412184 NCBI chr 2:119,758,622...119,778,650 JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:29407460)
(PMID:31134514)		 ARUK-UCL PMID:29407460 PMID:31134514 NCBI chr 7:36,465,921...36,471,509
Ensembl chr 7:36,465,324...36,471,516 		JBrowse link
G TRIM32 tripartite motif containing 32 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:257,051,421...257,066,911
Ensembl chr 1:257,054,228...257,066,909 		JBrowse link
negative regulation of toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:26,474,158...26,489,771
Ensembl chr 1:26,473,938...26,489,822 		JBrowse link
negative regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRAMD4 GRAM domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:2,873,466...2,947,804
Ensembl chr 5:2,873,428...2,947,785 		JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:95,840,906...95,860,858
Ensembl chr 6:95,840,908...95,860,858 		JBrowse link
G PTPRS protein tyrosine phosphatase receptor type S involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:73,607,815...73,680,685
Ensembl chr 2:73,574,854...73,680,686 		JBrowse link
G RAB7B RAB7B, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:66,635,636...66,666,034
Ensembl chr 9:66,635,638...66,666,036 		JBrowse link
negative regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB2 arrestin beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,161,776...52,170,362
Ensembl chr12:52,161,778...52,170,342 		JBrowse link
G CACTIN cactin, spliceosome C complex subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:75,049,250...75,065,990
Ensembl chr 2:75,049,261...75,065,299 		JBrowse link
G GPR108 G protein-coupled receptor 108 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:72,418,219...72,427,624
Ensembl chr 2:72,418,261...72,427,988 		JBrowse link
G GPS2 G protein pathway suppressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,664,869...52,667,643
Ensembl chr12:52,664,875...52,667,610 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:30,524,704...30,601,067
Ensembl chr 5:30,526,793...30,609,921 		JBrowse link
G IRF4 interferon regulatory factor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16236719) Ensembl
MGI		 PMID:16236719 GO_REF:0000107 NCBI chr 7:133,358...149,609
Ensembl chr 7:133,371...149,609 		JBrowse link
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:32,871,837...32,979,150
Ensembl chr 2:32,871,871...32,979,148 		JBrowse link
G LRRC14 leucine rich repeat containing 14 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:279,756...287,085
Ensembl chr 4:279,764...287,062 		JBrowse link
G MIR140 microRNA mir-140 ISO RGD PMID:31376096 RGD:329337378 NCBI chr 6:17,077,530...17,077,599
Ensembl chr 6:17,077,507...17,077,620 		JBrowse link
G MIR17 microRNA mir-17 involved_in ISO (PMID:26041742) ARUK-UCL PMID:26041742 NCBI chr11:60,734,656...60,734,732
Ensembl chr11:60,734,656...60,734,732 		JBrowse link
G MIR19A microRNA mir-19a involved_in ISO (PMID:26041742) ARUK-UCL PMID:26041742 NCBI chr11:60,734,939...60,735,020
Ensembl chr11:60,734,939...60,735,020 		JBrowse link
G NFKBIL1 NFKB inhibitor like 1 involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:23,673,002...23,685,089
Ensembl chr 7:23,669,595...23,685,087 		JBrowse link
G NLRP2B NLR family pyrin domain containing 2B involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 6:59,186,265...59,186,402 JBrowse link
G NLRP6 NLR family pyrin domain containing 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22763455) Ensembl
MGI		 PMID:22763455 GO_REF:0000107 NCBI chr 2:90,001...97,441
Ensembl chr 2:90,027...97,439 		JBrowse link
G OTUD4 OTU deubiquitinase 4 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:83,240,759...83,288,237
Ensembl chr 8:83,240,754...83,288,234 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:39,429,928...39,512,623
Ensembl chr 3:39,432,058...39,512,601 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:20728433) UniProt PMID:20728433 NCBI chr14:108,038,396...108,303,942
Ensembl chr14:108,039,431...108,303,929 		JBrowse link
G RNF115 ring finger protein 115 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:99,493,172...99,577,946
Ensembl chr 4:99,493,481...99,573,564 		JBrowse link
G SMPDL3B sphingomyelin phosphodiesterase acid like 3B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:85,060,639...85,084,483
Ensembl chr 6:85,060,317...85,084,480 		JBrowse link
G TYRO3 TYRO3 protein tyrosine kinase involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:129,811,540...129,829,395
Ensembl chr 1:129,811,544...129,829,014 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:47,601,133...47,645,327
Ensembl chr12:47,600,745...47,645,301 		JBrowse link
NLRP1 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLRP1 NLR family pyrin domain containing 1 involved_in ISO (PMID:27662089), (PMID:31484767)
(PMID:22665479), (PMID:33243852), (PMID:33420028), (PMID:33420033), (PMID:33852854), (PMID:35594856)		 UniProt PMID:22665479 PMID:27662089 PMID:31484767 PMID:33243852 PMID:33420028 More... NCBI chr12:51,479,968...51,495,540 JBrowse link
NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAT1 alpha tubulin acetyltransferase 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:23502856) Ensembl
MGI		 PMID:23502856 GO_REF:0000107 NCBI chr 7:23,173,138...23,185,463
Ensembl chr 7:23,173,447...23,185,458 		JBrowse link
G GKN2 gastrokine 2 acts_upstream_of_or_within ISO (PMID:32226647) MGI PMID:32226647 NCBI chr 3:73,443,856...73,451,789
Ensembl chr 3:73,443,856...73,451,789 		JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28928055) Ensembl
MGI		 PMID:28928055 GO_REF:0000107 NCBI chr 5:51,695,927...51,704,402
Ensembl chr 5:51,696,188...51,703,813 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 acts_upstream_of_or_within
involved_in		 ISO (PMID:22753929)
(PMID:17483456), (PMID:23582325), (PMID:25686105), (PMID:27043286), (PMID:27432880), (PMID:28465465), (PMID:28656979), (PMID:28943315), (PMID:30487600), (PMID:31189953), (PMID:33231615), (PMID:34554188), (PMID:34615873), (PMID:35114687), (PMID:35254907), (PMID:35559676), (PMID:36442502), (PMID:39173637)
(PMID:23582325), (PMID:26173909), (PMID:27043286), (PMID:28465465), (PMID:28656979), (PMID:28716882), (PMID:28943315), (PMID:30487600), (PMID:34615873), (PMID:34861190)		 MGI
UniProt		 PMID:17483456 PMID:22753929 PMID:23582325 PMID:25686105 PMID:26173909 More... NCBI chr 2:56,892,241...56,977,412
Ensembl chr 2:56,892,243...56,977,228 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:17,305,921...17,307,521
Ensembl chr 3:17,306,099...17,307,786 		JBrowse link
G SIRT2 sirtuin 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:23502856) Ensembl
MGI		 PMID:23502856 GO_REF:0000107 NCBI chr 6:47,682,427...47,703,408
Ensembl chr 6:47,682,429...47,703,384 		JBrowse link
NLRP6 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLRP6 NLR family pyrin domain containing 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:90,001...97,441
Ensembl chr 2:90,027...97,439 		JBrowse link
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNF34 ring finger protein 34 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:31,202,030...31,229,529
Ensembl chr14:31,206,674...31,229,484 		JBrowse link
nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFKBIA NFKB inhibitor alpha acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:18261938) MGI
Ensembl		 PMID:18261938 GO_REF:0000107 NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,507,822...64,511,277 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 involved_in ISO (PMID:11058605), (PMID:12791997), (PMID:12796777)
(PMID:27007849)		 UniProt PMID:11058605 PMID:12791997 PMID:12796777 PMID:27007849 NCBI chr18:42,464,667...42,509,135
Ensembl chr18:42,432,050...42,512,264 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894098) Ensembl
MGI		 PMID:11894098 GO_REF:0000107 NCBI chr 4:47,026,558...47,075,133
Ensembl chr 4:47,027,098...47,074,704 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:101,399,374...101,440,021
Ensembl chr  X:101,399,812...101,440,013 		JBrowse link
nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INAVA innate immunity activator involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:23,392,202...23,414,318
Ensembl chr10:23,392,099...23,412,712 		JBrowse link
G LACC1 laccase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:23,143,708...23,159,790
Ensembl chr11:23,141,133...23,159,649 		JBrowse link
G NFKBIA NFKB inhibitor alpha acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:18261938) MGI
Ensembl		 PMID:18261938 GO_REF:0000107 NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,507,822...64,511,277 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12527755)
(PMID:23892723)		 MGI
Ensembl		 PMID:12527755 PMID:23892723 GO_REF:0000107 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534 		JBrowse link
G OTULIN OTU deubiquitinase with linear linkage specificity involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:4,063,037...4,097,112
Ensembl chr16:4,063,071...4,093,198 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12527755) MGI
Ensembl		 PMID:12527755 GO_REF:0000107 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894098) Ensembl
MGI		 PMID:11894098 GO_REF:0000107 NCBI chr 4:47,026,558...47,075,133
Ensembl chr 4:47,027,098...47,074,704 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:101,399,374...101,440,021
Ensembl chr  X:101,399,812...101,440,013 		JBrowse link
pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CGAS cyclic GMP-AMP synthase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:92,483,253...92,500,376
Ensembl chr 1:92,483,327...92,504,307 		JBrowse link
G CLEC4E C-type lectin domain family 4 member E involved_in ISO (PMID:24101491) UniProt PMID:24101491 NCBI chr 5:63,219,229...63,228,566 JBrowse link
G INAVA innate immunity activator involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:23,392,202...23,414,318
Ensembl chr10:23,392,099...23,412,712 		JBrowse link
G LACC1 laccase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:23,143,708...23,159,790
Ensembl chr11:23,141,133...23,159,649 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 involved_in ISO (PMID:31649195) UniProt PMID:31649195 NCBI chr18:42,464,667...42,509,135
Ensembl chr18:42,432,050...42,512,264 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534 		JBrowse link
G RNF144A ring finger protein 144A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:128,746,910...128,868,133
Ensembl chr 3:128,747,722...128,817,537 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:141,359,402...141,367,222
Ensembl chr 2:141,358,993...141,367,198 		JBrowse link
positive regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GBP2 guanylate binding protein 2, interferon-inducible involved_in ISO (PMID:25774715), (PMID:25774716) UniProt PMID:25774715 PMID:25774716 NCBI chr 4:127,387,222...127,408,729
Ensembl chr 4:127,379,740...127,408,699 		JBrowse link
positive regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTK Bruton tyrosine kinase involved_in ISO (PMID:25704810) UniProt PMID:25704810 NCBI chr  X:82,981,512...83,014,475
Ensembl chr  X:82,981,515...83,014,573 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (PMID:37832545) UniProt PMID:37832545 NCBI chr 1:58,482,046...58,548,087
Ensembl chr 1:58,481,956...58,548,057 		JBrowse link
G SLC19A1 solute carrier family 19 member 1 involved_in ISO (PMID:36745868) UniProt PMID:36745868 NCBI chr13:207,986,094...208,007,855
Ensembl chr13:207,986,098...208,007,675 		JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:8,827,363...8,852,814
Ensembl chr 5:8,826,840...8,852,776 		JBrowse link
G ZDHHC9 zinc finger DHHC-type palmitoyltransferase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:106,397,139...106,436,103
Ensembl chr  X:106,401,245...106,436,014 		JBrowse link
positive regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD17 ankyrin repeat domain 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:69,360,641...69,531,418
Ensembl chr 8:69,360,649...69,531,286 		JBrowse link
G DDX60 DExD/H-box helicase 60 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:21,077,491...21,163,563
Ensembl chr14:21,083,350...21,163,561 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:20,647,698...20,656,691
Ensembl chr12:20,647,699...20,656,683 		JBrowse link
positive regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAT1 alpha tubulin acetyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23502856) Ensembl
MGI		 PMID:23502856 GO_REF:0000107 NCBI chr 7:23,173,138...23,185,463
Ensembl chr 7:23,173,447...23,185,458 		JBrowse link
G BRCC3 BRCA1/BRCA2-containing complex subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:125,383,392...125,439,082
Ensembl chr  X:125,383,414...125,439,082 		JBrowse link
G BTK Bruton tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:82,981,512...83,014,475
Ensembl chr  X:82,981,515...83,014,573 		JBrowse link
G CD36 CD36 molecule involved_in ISO (PMID:23812099) UniProt PMID:23812099 NCBI chr 9:99,685,748...99,782,296
Ensembl chr 9:99,605,181...99,782,105 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in ISO (PMID:31511697) UniProt PMID:31511697 NCBI chr  X:36,988,031...37,005,496
Ensembl chr  X:36,988,031...37,018,202 		JBrowse link
G DHX33 DEAH-box helicase 33 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:51,527,071...51,547,334
Ensembl chr12:51,527,083...51,546,448 		JBrowse link
G KCNK6 potassium two pore domain channel subfamily K member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:47,237,665...47,249,178
Ensembl chr 6:47,238,685...47,249,136 		JBrowse link
G LATS1 large tumor suppressor kinase 1 involved_in ISO (PMID:39173637) UniProt PMID:39173637 NCBI chr 1:16,274,955...16,320,980
Ensembl chr 1:16,274,970...16,320,604 		JBrowse link
G LATS2 large tumor suppressor kinase 2 involved_in ISO (PMID:39173637) UniProt PMID:39173637 NCBI chr11:1,225,523...1,265,970
Ensembl chr11:1,225,527...1,265,946 		JBrowse link
G LOC100522887 caspase-13 involved_in ISO (PMID:26173909) UniProt PMID:26173909 NCBI chr 9:35,167,567...35,185,791 JBrowse link
G LOC100523492 guanylate-binding protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:127,289,938...127,303,065
Ensembl chr 4:127,289,956...127,303,011 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874 		JBrowse link
G MARK4 microtubule affinity regulating kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:51,665,923...51,700,553
Ensembl chr 6:51,665,918...51,700,552 		JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:31,850,646...31,869,273
Ensembl chr17:31,850,900...31,869,188 		JBrowse link
G MIR21 microRNA mir-21 ISO RGD PMID:29084974 RGD:41404715 NCBI chr12:36,065,267...36,065,358
Ensembl chr12:36,065,267...36,065,358 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr13:22,976,951...22,979,568
Ensembl chr13:22,966,137...22,983,109 		JBrowse link
G NEK7 NIMA related kinase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:20,966,660...21,124,283
Ensembl chr10:20,966,651...21,124,271 		JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:31,415,188...31,476,502
Ensembl chr14:31,415,193...31,476,472 		JBrowse link
G PLCG2 phospholipase C gamma 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:32514138) ARUK-UCL
Ensembl		 PMID:32514138 GO_REF:0000107 NCBI chr 6:6,433,146...6,603,092
Ensembl chr 6:6,433,153...6,603,060 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:136,497,780...136,522,630
Ensembl chr 2:136,494,541...136,522,646 		JBrowse link
G PRKD1 protein kinase D1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:69,527,743...69,872,374
Ensembl chr 7:69,527,811...69,872,863 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:106,692,102...106,758,101
Ensembl chr 4:106,686,604...106,758,099 		JBrowse link
G STMP1 short transmembrane mitochondrial protein 1 involved_in ISO (PMID:31836654) UniProt PMID:31836654 NCBI chr13:138,779,975...138,781,436 JBrowse link
G STMP1 short transmembrane mitochondrial protein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr18:13,641,541...13,665,565 JBrowse link
G TLR4 toll like receptor 4 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISO (PMID:23812099) UniProt PMID:23812099 NCBI chr 8:30,159,744...30,180,650
Ensembl chr 8:30,159,754...30,180,650 		JBrowse link
G USP50 ubiquitin specific peptidase 50 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:28094437) MGI
Ensembl		 PMID:28094437 GO_REF:0000107 NCBI chr 1:121,272,977...121,307,029
Ensembl chr 1:121,273,043...121,307,075 		JBrowse link
G ZDHHC1 zinc finger DHHC-type containing 1 involved_in ISO (PMID:39173637) UniProt PMID:39173637 NCBI chr 6:28,046,099...28,071,535
Ensembl chr 6:28,049,949...28,071,540 		JBrowse link
G ZDHHC5 zinc finger DHHC-type palmitoyltransferase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:13,250,967...13,276,517
Ensembl chr 2:13,250,970...13,276,114 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:26,122,362...26,154,414
Ensembl chr14:26,122,386...26,154,781 		JBrowse link
G SLC46A2 solute carrier family 46 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:253,559,545...253,571,015
Ensembl chr 1:253,559,546...253,570,113 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NAGK N-acetylglucosamine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:71,496,191...71,513,020
Ensembl chr 3:71,500,337...71,512,955 		JBrowse link
G PELI3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) MGI PMID:23892723 NCBI chr 2:5,950,552...5,959,786
Ensembl chr 2:5,948,849...5,959,734 		JBrowse link
G SLC15A3 solute carrier family 15 member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:10,799,927...10,814,363
Ensembl chr 2:10,800,503...10,814,389 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:26,122,362...26,154,414
Ensembl chr14:26,122,386...26,154,781 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
positive regulation of pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZDHHC5 zinc finger DHHC-type palmitoyltransferase 5 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:13,250,967...13,276,517
Ensembl chr 2:13,250,970...13,276,114 		JBrowse link
positive regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD17 ankyrin repeat domain 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:69,360,641...69,531,418
Ensembl chr 8:69,360,649...69,531,286 		JBrowse link
G DDX60 DExD/H-box helicase 60 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:21,077,491...21,163,563
Ensembl chr14:21,083,350...21,163,561 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:20,647,698...20,656,691
Ensembl chr12:20,647,699...20,656,683 		JBrowse link
G OASL 2'-5'-oligoadenylate synthetase like involved_in ISO (PMID:25925578) ARUK-UCL PMID:25925578 NCBI chr14:40,900,050...40,917,189
Ensembl chr14:40,899,856...40,917,266 		JBrowse link
G PUM1 pumilio RNA binding family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:87,546,388...87,687,483
Ensembl chr 6:87,547,320...87,687,442 		JBrowse link
G PUM2 pumilio RNA binding family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:117,857,930...117,965,564
Ensembl chr 3:117,883,673...117,965,293 		JBrowse link
G TRIM15 tripartite motif containing 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:22,730,372...22,742,941
Ensembl chr 7:22,731,274...22,743,146 		JBrowse link
G USP15 ubiquitin specific peptidase 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:26,964,380...27,082,549
Ensembl chr 5:26,964,553...27,097,444 		JBrowse link
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 involved_in ISO (PMID:21102435) UniProt PMID:21102435 NCBI chr18:10,529,805...10,588,913
Ensembl chr18:10,531,897...10,588,832 		JBrowse link
G ZCCHC3 zinc finger CCHC-type containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:34,882,812...34,885,632
Ensembl chr17:34,882,816...34,885,505 		JBrowse link
positive regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYBA cytochrome b-245 alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:1,015,212...1,021,422
Ensembl chr 6:1,015,162...1,021,420 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:85,732,082...85,747,552
Ensembl chr 2:85,732,189...85,750,858 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:16267105) UniProt PMID:16267105 NCBI chr11:7,195,556...7,321,071 JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:56,200,455...56,296,151
Ensembl chr15:56,200,455...56,295,064 		JBrowse link
G PJA2 praja ring finger ubiquitin ligase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:114,319,972...114,675,761
Ensembl chr 2:114,319,991...114,558,272 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:53,374,559...53,394,172
Ensembl chr 9:53,375,644...53,394,165 		JBrowse link
G TLR1 toll like receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:30,147,600...30,155,454
Ensembl chr 8:30,147,624...30,155,466 		JBrowse link
positive regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:85,732,082...85,747,552
Ensembl chr 2:85,732,189...85,750,858 		JBrowse link
G FLOT1 flotillin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:23,253,157...23,265,165
Ensembl chr 7:23,253,162...23,265,106 		JBrowse link
G PELI1 pellino E3 ubiquitin protein ligase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19734906) Ensembl
MGI		 PMID:19734906 GO_REF:0000107 NCBI chr 3:77,740,460...77,796,911
Ensembl chr 3:77,713,489...77,796,914 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:106,692,102...106,758,101
Ensembl chr 4:106,686,604...106,758,099 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in ISO (PMID:17322885) BHF-UCL PMID:17322885 NCBI chr 9:53,374,559...53,394,172
Ensembl chr 9:53,375,644...53,394,165 		JBrowse link
G TRIM3 tripartite motif containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:3,256,915...3,281,846
Ensembl chr 9:3,272,798...3,282,366 		JBrowse link
G WDFY1 WD repeat and FYVE domain containing 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr15:125,674,142...125,720,187
Ensembl chr15:125,669,842...125,720,158 		JBrowse link
positive regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:142,348,036...142,349,686
Ensembl chr 2:142,346,360...142,349,581 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:85,732,082...85,747,552
Ensembl chr 2:85,732,189...85,750,858 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:16267105) UniProt PMID:16267105 NCBI chr11:7,195,556...7,321,071 JBrowse link
G IFI35 interferon induced protein 35 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:19,879,386...19,890,330
Ensembl chr12:19,879,387...19,890,314 		JBrowse link
G LBP lipopolysaccharide binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:41,398,935...41,429,467
Ensembl chr17:41,393,818...41,429,551 		JBrowse link
G LTF lactotransferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:29,413,886...29,445,751
Ensembl chr13:29,413,886...29,445,739 		JBrowse link
G NINJ1 ninjurin 1 involved_in ISO (PMID:25860173) UniProt PMID:25860173 NCBI chr 3:42,654,536...42,672,830
Ensembl chr 3:42,654,228...42,672,778 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:15,315,283...15,336,785
Ensembl chr 2:15,315,282...15,334,820 		JBrowse link
G PELI1 pellino E3 ubiquitin protein ligase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19734906) Ensembl
MGI		 PMID:19734906 GO_REF:0000107 NCBI chr 3:77,740,460...77,796,911
Ensembl chr 3:77,713,489...77,796,914 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:106,692,102...106,758,101
Ensembl chr 4:106,686,604...106,758,099 		JBrowse link
G TICAM2 toll like receptor adaptor molecule 2 involved_in ISO (PMID:22685567)
(PMID:19412184)		 UniProt PMID:19412184 PMID:22685567 NCBI chr 2:119,758,622...119,778,650 JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:53,374,559...53,394,172
Ensembl chr 9:53,375,644...53,394,165 		JBrowse link
G WDFY1 WD repeat and FYVE domain containing 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr15:125,674,142...125,720,187
Ensembl chr15:125,669,842...125,720,158 		JBrowse link
G ZNRF1 zinc and ring finger 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:12,555,655...12,668,807 JBrowse link
G ZNRF1 zinc and ring finger 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 6:12,555,664...12,668,804 JBrowse link
positive regulation of toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX3X DEAD-box helicase 3 X-linked involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:36,988,031...37,005,496
Ensembl chr  X:36,988,031...37,018,202 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:106,692,102...106,758,101
Ensembl chr 4:106,686,604...106,758,099 		JBrowse link
G RSAD2 radical S-adenosyl methionine domain containing 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:128,880,853...128,897,809
Ensembl chr 3:128,877,186...128,897,815 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:26,122,362...26,154,414
Ensembl chr14:26,122,386...26,154,781 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:26,363,808...26,384,933
Ensembl chr  X:26,365,027...26,384,760 		JBrowse link
positive regulation of toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX3X DEAD-box helicase 3 X-linked involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:36,988,031...37,005,496
Ensembl chr  X:36,988,031...37,018,202 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:26,122,362...26,154,414
Ensembl chr14:26,122,386...26,154,781 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:26,363,808...26,384,933
Ensembl chr  X:26,365,027...26,384,760 		JBrowse link
positive regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB1 high mobility group box 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr11:7,195,556...7,321,071 JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:106,692,102...106,758,101
Ensembl chr 4:106,686,604...106,758,099 		JBrowse link
G RSAD2 radical S-adenosyl methionine domain containing 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:128,880,853...128,897,809
Ensembl chr 3:128,877,186...128,897,815 		JBrowse link
G RTN4 reticulon 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:86,180,022...86,252,126
Ensembl chr 3:86,180,022...86,252,126 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:26,122,362...26,154,414
Ensembl chr14:26,122,386...26,154,781 		JBrowse link
G TLR9 toll like receptor 9 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr13:34,353,444...34,370,990
Ensembl chr13:34,349,609...34,357,673 		JBrowse link
G ZDHHC3 zinc finger DHHC-type palmitoyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:28,100,529...28,176,733
Ensembl chr13:28,098,007...28,176,738 		JBrowse link
positive regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GDI1 GDP dissociation inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:124,960,835...124,966,833
Ensembl chr  X:124,960,990...124,966,832 		JBrowse link
G LRCH4 leucine rich repeats and calponin homology domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,497,456...8,511,361
Ensembl chr 3:8,499,285...8,511,262 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:20728433) UniProt PMID:20728433 NCBI chr14:108,038,396...108,303,942
Ensembl chr14:108,039,431...108,303,929 		JBrowse link
regulation of cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR708 microRNA mir-708 involved_in ISO (PMID:31599428) ARUK-UCL PMID:31599428 NCBI chr 9:13,780,171...13,780,250
Ensembl chr 9:13,780,171...13,780,250 		JBrowse link
regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRF1 interferon regulatory factor 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:134,776,122...134,783,646
Ensembl chr 2:134,776,129...134,783,801 		JBrowse link
G IRF7 interferon regulatory factor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:372,235...375,572
Ensembl chr 2:372,238...375,378 		JBrowse link
regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRF7 interferon regulatory factor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:372,235...375,572
Ensembl chr 2:372,238...375,378 		JBrowse link
regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:103,041,029...103,096,741
Ensembl chr 3:103,041,221...103,096,738 		JBrowse link
G KCNK13 potassium two pore domain channel subfamily K member 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:111,866,471...111,981,304
Ensembl chr 7:111,867,546...111,980,663 		JBrowse link
regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC15A2 solute carrier family 15 member 2 involved_in ISO (PMID:29784761) UniProt PMID:29784761 NCBI chr13:138,595,942...138,634,473
Ensembl chr13:138,595,958...138,632,675 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:26,122,362...26,154,414
Ensembl chr14:26,122,386...26,154,781 		JBrowse link
regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PELI3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) MGI PMID:23892723 NCBI chr 2:5,950,552...5,959,786
Ensembl chr 2:5,948,849...5,959,734 		JBrowse link
regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOP53 NOP53 ribosome biogenesis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:53,443,453...53,451,707
Ensembl chr 6:53,443,385...53,452,017 		JBrowse link
regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLOT2 flotillin 2 NOT|involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chr12:45,102,205...45,120,503
Ensembl chr12:45,101,531...45,120,455 		JBrowse link
G HCFC2 host cell factor C2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28970238) Ensembl
MGI		 PMID:28970238 GO_REF:0000107 NCBI chr 5:80,366,826...80,409,798
Ensembl chr 5:80,368,240...80,409,775 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:40,470,970...40,524,862
Ensembl chr17:40,471,009...40,524,860 		JBrowse link
regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:39,089,157...39,124,969
Ensembl chr13:39,089,077...39,129,781 		JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (PMID:27219021) UniProt PMID:27219021 NCBI chr 5:79,356,046...79,412,235
Ensembl chr 5:79,356,067...79,412,235 		JBrowse link
G FLOT1 flotillin 1 NOT|involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chr 7:23,253,157...23,265,165
Ensembl chr 7:23,253,162...23,265,106 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:46,434,757...46,523,626
Ensembl chr16:46,511,521...46,523,609 		JBrowse link
regulation of toll-like receptor 6 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31134514) ARUK-UCL PMID:31134514 NCBI chr 7:36,465,921...36,471,509
Ensembl chr 7:36,465,324...36,471,516 		JBrowse link
regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100158069 Fc receptor-like protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:92,460,744...92,506,002
Ensembl chr 4:92,460,862...92,504,024 		JBrowse link
regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein involved_in ISO (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chr13:189,434,854...189,716,120
Ensembl chr13:189,435,094...189,716,056 		JBrowse link
G CD36 CD36 molecule involved_in ISO (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chr 9:99,685,748...99,782,296
Ensembl chr 9:99,605,181...99,782,105 		JBrowse link
G ESR1 estrogen receptor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:22659029) MGI
Ensembl		 PMID:22659029 GO_REF:0000107 NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363 		JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:124,619,887...124,629,638
Ensembl chr 4:124,621,261...124,629,638 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:20616063) UniProt PMID:20616063 NCBI chr15:56,200,455...56,296,151
Ensembl chr15:56,200,455...56,295,064 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA InterPro GO_REF:0000002 NCBI chr  X:26,363,808...26,384,933
Ensembl chr  X:26,365,027...26,384,760 		JBrowse link
RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLPB ClpB family mitochondrial disaggregase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:6,836,367...7,089,896
Ensembl chr 9:6,836,390...6,981,892 		JBrowse link
G LSM14A LSM14A mRNA processing body assembly factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22745163) Ensembl
MGI		 PMID:22745163 GO_REF:0000107 NCBI chr 6:43,847,882...43,901,697
Ensembl chr 6:43,847,732...43,903,587 		JBrowse link
G MAVS mitochondrial antiviral signaling protein acts_upstream_of_or_within ISO (PMID:22745163) MGI PMID:22745163 NCBI chr17:31,850,646...31,869,273
Ensembl chr17:31,850,900...31,869,188 		JBrowse link
G PHB1 prohibitin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:25,596,520...25,609,693
Ensembl chr12:25,596,523...25,609,706 		JBrowse link
G PHB2 prohibitin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:63,751,566...63,756,480
Ensembl chr 5:63,751,558...63,756,478 		JBrowse link
G RIGI RNA sensor RIG-I involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:33,891,720...33,976,151
Ensembl chr10:33,891,763...33,933,455 		JBrowse link
G RNF135 ring finger protein 135 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:42,793,755...42,808,937
Ensembl chr12:42,795,409...42,808,897 		JBrowse link
G TRIM25 tripartite motif containing 25 NOT|involved_in ISO (PMID:31006531) UniProt PMID:31006531 NCBI chr12:33,184,039...33,212,440
Ensembl chr12:33,184,049...33,212,398 		JBrowse link
stimulatory C-type lectin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC7A C-type lectin domain containing 7A involved_in ISO (PMID:19136564) ARUK-UCL PMID:19136564 NCBI chr 5:61,832,910...61,846,441
Ensembl chr 5:61,832,954...61,846,434 		JBrowse link
G KLRD1 killer cell lectin like receptor D1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:61,662,083...61,673,109
Ensembl chr 5:61,666,654...61,673,129 		JBrowse link
G KLRK1 killer cell lectin like receptor K1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12645935) Ensembl
MGI		 PMID:12645935 GO_REF:0000107 NCBI chr 5:61,646,691...61,655,386
Ensembl chr 5:61,647,043...61,656,192 		JBrowse link
G LOC100519314 natural killer cells antigen CD94 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:61,724,744...61,736,667 JBrowse link
G LOC100523789 NKG2-A/NKG2-B type II integral membrane protein involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:61,621,869...61,633,693 JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:6,433,146...6,603,092
Ensembl chr 6:6,433,153...6,603,060 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:2,103,706...2,160,886
Ensembl chr14:2,056,670...2,161,171 		JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:45,309,199...45,312,562
Ensembl chr 6:45,309,201...45,312,539 		JBrowse link
stimulatory killer cell immunoglobulin-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:45,309,199...45,312,562
Ensembl chr 6:45,309,201...45,312,539 		JBrowse link
TIRAP-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TIRAP TIR domain containing adaptor protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:53,374,559...53,394,172
Ensembl chr 9:53,375,644...53,394,165 		JBrowse link
toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB1 high mobility group box 1 involved_in IDA (PMID:14660645) UniProt PMID:14660645 NCBI chr11:7,195,556...7,321,071 JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:10549626) Ensembl
MGI
GO_Central		 PMID:10549626 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:124,717,604...124,724,855
Ensembl chr  X:124,717,612...124,724,860 		JBrowse link
G LGALS9 galectin 9 NOT|involved_in ISO (PMID:16116184) UniProt PMID:16116184 NCBI chr12:44,155,079...44,173,634 JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:15220916) Ensembl
MGI		 PMID:15220916 GO_REF:0000107 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:108,038,396...108,303,942
Ensembl chr14:108,039,431...108,303,929 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11894098) MGI
Ensembl		 PMID:11894098 GO_REF:0000107 NCBI chr 4:47,026,558...47,075,133
Ensembl chr 4:47,027,098...47,074,704 		JBrowse link
G TLR2 toll like receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,993...75,428,330 		JBrowse link
G TNIP2 TNFAIP3 interacting protein 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:1,530,534...1,554,677
Ensembl chr 8:1,533,429...1,554,683 		JBrowse link
toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD86 CD86 molecule involved_in ISO (PMID:25158758) UniProt PMID:25158758 NCBI chr13:138,427,573...138,504,307
Ensembl chr13:138,427,533...138,504,310 		JBrowse link
G COLEC12 collectin subfamily member 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:105,808,157...106,000,197
Ensembl chr 6:105,808,221...106,007,730 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:66,138,157...66,160,568
Ensembl chr16:66,139,535...66,160,538 		JBrowse link
G LGALS9 galectin 9 involved_in ISO PMID:25158758 UniProt PMID:25158758 RGD:10054077 NCBI chr12:44,155,079...44,173,634 JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:38,851,083...38,867,427
Ensembl chr14:38,851,918...38,859,409 		JBrowse link
G RFTN1 raftlin, lipid raft linker 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21266579) MGI
Ensembl		 PMID:21266579 GO_REF:0000107 NCBI chr13:3,454,448...3,675,072
Ensembl chr13:3,454,454...3,674,998 		JBrowse link
G RNF170 ring finger protein 170 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:31076723) MGI
Ensembl		 PMID:31076723 GO_REF:0000107 NCBI chr17:11,777,942...11,817,920
Ensembl chr17:11,780,129...11,816,049 		JBrowse link
G SCARA3 scavenger receptor class A member 3 NOT|involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chr14:11,367,402...11,403,173
Ensembl chr14:11,367,427...11,410,978 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:51,772,635...51,794,107
Ensembl chr12:51,773,448...51,794,104 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:74,004,566...74,021,100
Ensembl chr 2:74,004,308...74,021,873 		JBrowse link
G TLR3 toll like receptor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:46,966,262...46,977,774
Ensembl chr15:46,969,006...46,979,291 		JBrowse link
G TNF tumor necrosis factor involved_in ISO PMID:25158758 UniProt PMID:25158758 RGD:10054077 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
G TNIP2 TNFAIP3 interacting protein 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:1,530,534...1,554,677
Ensembl chr 8:1,533,429...1,554,683 		JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:4,898,414...4,909,833
Ensembl chr 2:4,898,409...4,909,856 		JBrowse link
toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:142,348,036...142,349,686
Ensembl chr 2:142,346,360...142,349,581 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:111,316,178...111,351,669
Ensembl chr14:111,315,141...111,351,868 		JBrowse link
G ECSIT ECSIT signaling integrator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:70,154,861...70,170,762
Ensembl chr 2:70,154,843...70,170,744 		JBrowse link
G HMGB1 high mobility group box 1 involved_in IDA (PMID:14660645) UniProt PMID:14660645 NCBI chr11:7,195,556...7,321,071 JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:10549626) GO_Central
MGI		 PMID:10549626 GO_REF:0000033 NCBI chr  X:124,717,604...124,724,855
Ensembl chr  X:124,717,612...124,724,860 		JBrowse link
G IRAK2 interleukin 1 receptor associated kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:66,350,606...66,416,834
Ensembl chr13:66,350,606...66,416,827 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:54,701,733...54,706,079
Ensembl chr 6:54,701,668...54,707,151 		JBrowse link
G LGALS9 galectin 9 NOT|involved_in ISO (PMID:16116184) UniProt PMID:16116184 NCBI chr12:44,155,079...44,173,634 JBrowse link
G LY96 lymphocyte antigen 96 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:61,919,806...61,950,712
Ensembl chr 4:61,926,064...61,950,697 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:75,793,273...75,903,710
Ensembl chr 4:75,793,492...75,903,496 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:58,482,046...58,548,087
Ensembl chr 1:58,481,956...58,548,057 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr13:22,976,951...22,979,568
Ensembl chr13:22,966,137...22,983,109 		JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase involved_in IEA Ensembl GO_REF:0000107 Ensembl chr12:20,271,351...20,279,777 JBrowse link
G NFKBIA NFKB inhibitor alpha acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:18261938) MGI
Ensembl		 PMID:18261938 GO_REF:0000107 NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,507,822...64,511,277 		JBrowse link
G NMI N-myc and STAT interactor involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:941,379...966,519
Ensembl chr15:941,475...967,321 		JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:38,851,083...38,867,427
Ensembl chr14:38,851,918...38,859,409 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:108,038,396...108,303,942
Ensembl chr14:108,039,431...108,303,929 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894098) Ensembl
MGI		 PMID:11894098 GO_REF:0000107 NCBI chr 4:47,026,558...47,075,133
Ensembl chr 4:47,027,098...47,074,704 		JBrowse link
G S100A14 S100 calcium binding protein A14 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:96,027,746...96,029,878
Ensembl chr 4:96,027,639...96,029,869 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:51,772,635...51,794,107
Ensembl chr12:51,773,448...51,794,104 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:28,880,210...28,929,964
Ensembl chr 5:28,880,205...28,929,963 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:74,004,566...74,021,100
Ensembl chr 2:74,004,308...74,021,873 		JBrowse link
G TICAM2 toll like receptor adaptor molecule 2 involved_in ISO (PMID:28630139) UniProt PMID:28630139 NCBI chr 2:119,758,622...119,778,650 JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:53,374,559...53,394,172
Ensembl chr 9:53,375,644...53,394,165 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:25549946) Ensembl
MGI
GO_Central		 PMID:25549946 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
G TMEM126A transmembrane protein 126A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25549946) Ensembl
MGI		 PMID:25549946 GO_REF:0000107 NCBI chr 9:19,576,241...19,585,869
Ensembl chr 9:19,576,295...19,585,277 		JBrowse link
G TNIP3 TNFAIP3 interacting protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:102,892,427...102,990,902
Ensembl chr 8:102,892,366...102,991,848 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in IEA Ensembl GO_REF:0000107
G TRAF6 TNF receptor associated factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:24,602,749...24,628,263
Ensembl chr 2:24,602,804...24,626,072 		JBrowse link
G TRIL TLR4 interactor with leucine rich repeats involved_in ISO (PMID:19710467) UniProt PMID:19710467 NCBI chr18:43,725,910...43,833,993 JBrowse link
toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:22,976,951...22,979,568
Ensembl chr13:22,966,137...22,983,109 		JBrowse link
G TIRAP TIR domain containing adaptor protein NOT|involved_in ISO (PMID:12447442) BHF-UCL PMID:12447442 NCBI chr 9:53,374,559...53,394,172
Ensembl chr 9:53,375,644...53,394,165 		JBrowse link
G TLR5 toll like receptor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:19,387,666...19,410,024
Ensembl chr10:19,387,666...19,410,024 		JBrowse link
toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:66,138,157...66,160,568
Ensembl chr16:66,139,535...66,160,538 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:108,038,396...108,303,942
Ensembl chr14:108,039,431...108,303,929 		JBrowse link
G PRPS2 phosphoribosyl pyrophosphate synthetase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:9,505,034...9,531,044
Ensembl chr  X:9,503,953...9,530,086 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:51,772,635...51,794,107
Ensembl chr12:51,773,448...51,794,104 		JBrowse link
G TLR7 toll like receptor 7 involved_in ISO (PMID:12032557)
(PMID:14976261)		 GO_Central
UniProt		 PMID:12032557 PMID:14976261 NCBI chr  X:9,573,178...9,576,987 JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:4,898,414...4,909,833
Ensembl chr 2:4,898,409...4,909,856 		JBrowse link
toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr13:22,976,951...22,979,568
Ensembl chr13:22,966,137...22,983,109 		JBrowse link
G PRPS2 phosphoribosyl pyrophosphate synthetase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:9,505,034...9,531,044
Ensembl chr  X:9,503,953...9,530,086 		JBrowse link
G TLR7 toll like receptor 7 involved_in ISO (PMID:12032557) GO_Central PMID:12032557 NCBI chr  X:9,573,178...9,576,987 JBrowse link
G TLR8 toll like receptor 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:9,551,284...9,616,762
Ensembl chr  X:9,597,604...9,616,757 		JBrowse link
toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPG5 ectopic P-granules 5 autophagy tethering factor acts_upstream_of_positive_effect
involved_in		 ISO
IEA		 (PMID:29130391) UniProt
Ensembl		 PMID:29130391 GO_REF:0000107 NCBI chr 1:95,493,779...95,616,794
Ensembl chr 1:95,498,720...95,616,755 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:66,138,157...66,160,568
Ensembl chr16:66,139,535...66,160,538 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:83,607,222...83,732,668
Ensembl chr 5:83,604,294...83,684,604 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:108,038,396...108,303,942
Ensembl chr14:108,039,431...108,303,929 		JBrowse link
G TLR9 toll like receptor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:34,353,444...34,370,990
Ensembl chr13:34,349,609...34,357,673 		JBrowse link
G TNIP2 TNFAIP3 interacting protein 2 involved_in ISO (PMID:16633345) UniProt PMID:16633345 NCBI chr 8:1,530,534...1,554,677
Ensembl chr 8:1,533,429...1,554,683 		JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:4,898,414...4,909,833
Ensembl chr 2:4,898,409...4,909,856 		JBrowse link
toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP3B1 adaptor related protein complex 3 subunit beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20847273) Ensembl
MGI		 PMID:20847273 GO_REF:0000107 NCBI chr 2:86,875,922...87,142,722
Ensembl chr 2:86,873,290...87,142,768 		JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:130,645,427...130,653,317
Ensembl chr 4:130,645,216...130,657,995 		JBrowse link
G CD86 CD86 molecule acts_upstream_of_or_within ISO (PMID:19734906) MGI PMID:19734906 NCBI chr13:138,427,573...138,504,307
Ensembl chr13:138,427,533...138,504,310 		JBrowse link
G CHADL chondroadherin like involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:7,246,892...7,258,962
Ensembl chr 5:7,248,444...7,253,170 		JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30990796) Ensembl
MGI		 PMID:30990796 GO_REF:0000107 NCBI chr 2:6,430,158...6,436,173
Ensembl chr 2:6,430,153...6,436,173 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 IEP RGD PMID:27832756 RGD:34888235 NCBI chr 5:30,524,704...30,601,067
Ensembl chr 5:30,526,793...30,609,921 		JBrowse link
G LRRC19 leucine rich repeat containing 19 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:19679103) Ensembl
GO_Central
MGI		 PMID:19679103 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:196,129,816...196,142,696
Ensembl chr 1:196,129,905...196,142,701 		JBrowse link
G LY96 lymphocyte antigen 96 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:61,919,806...61,950,712
Ensembl chr 4:61,926,064...61,950,697 		JBrowse link
G MAPKAPK2 MAPK activated protein kinase 2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:67,314,651...67,365,060
Ensembl chr 9:67,314,484...67,365,059 		JBrowse link
G MAPKAPK3 MAPK activated protein kinase 3 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr13:33,097,329...33,125,820
Ensembl chr13:33,097,393...33,125,818 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:157,261,419...157,273,119
Ensembl chr13:157,261,419...157,272,688 		JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:6,433,146...6,603,092
Ensembl chr 6:6,433,153...6,603,060 		JBrowse link
G RPS6KA3 ribosomal protein S6 kinase A3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:16,452,401...16,576,854
Ensembl chr  X:16,452,405...16,576,859 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:74,004,566...74,021,100
Ensembl chr 2:74,004,308...74,021,873 		JBrowse link
G TIFAB TIFA inhibitor involved_in
acts_upstream_of_negative_effect		 IEA
ISO		 (PMID:26458771) Ensembl
MGI		 PMID:26458771 GO_REF:0000107 NCBI chr 2:137,675,245...137,678,880
Ensembl chr 2:137,672,407...137,678,612 		JBrowse link
G TLR1 toll like receptor 1 involved_in ISO
IBA
IEA		 RGD
GO_Central
Ensembl
InterPro		 PMID:16973131 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 RGD:1643119 NCBI chr 8:30,147,600...30,155,454
Ensembl chr 8:30,147,624...30,155,466 		JBrowse link
G TLR10 toll like receptor 10 involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 8:30,124,895...30,134,854
Ensembl chr 8:30,124,895...30,134,854 		JBrowse link
G TLR2 toll like receptor 2 involved_in ISO
IBA
IEA		 RGD
GO_Central
UniProt
Ensembl
InterPro		 PMID:16973131 PMID:18353287 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 RGD:1643119 RGD:5684896 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,993...75,428,330 		JBrowse link
G TLR3 toll like receptor 3 involved_in ISO
IBA
IEA		 RGD
GO_Central
Ensembl		 PMID:16973131 GO_REF:0000033 GO_REF:0000107 RGD:1643119 NCBI chr15:46,966,262...46,977,774
Ensembl chr15:46,969,006...46,979,291 		JBrowse link
G TLR4 toll like receptor 4 involved_in ISO
IEA		 RGD
Ensembl
InterPro		 PMID:16973131 GO_REF:0000002 GO_REF:0000107 RGD:1643119 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
G TLR5 toll like receptor 5 involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:19,387,666...19,410,024
Ensembl chr10:19,387,666...19,410,024 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISO
IBA
IEA		 RGD
GO_Central
InterPro		 PMID:16973131 PMID:18353287 GO_REF:0000002 GO_REF:0000033 RGD:1643119 RGD:5684896 NCBI chr 8:30,159,744...30,180,650
Ensembl chr 8:30,159,754...30,180,650 		JBrowse link
G TLR9 toll like receptor 9 involved_in ISO
IEA
IBA		 RGD
Ensembl
GO_Central		 PMID:16973131 GO_REF:0000033 GO_REF:0000107 RGD:1643119 NCBI chr13:34,353,444...34,370,990
Ensembl chr13:34,349,609...34,357,673 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in IEA Ensembl GO_REF:0000107
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16415873) InterPro
MGI
Ensembl		 PMID:16415873 GO_REF:0000002 GO_REF:0000107 NCBI chr 2:4,898,414...4,909,833
Ensembl chr 2:4,898,409...4,909,856 		JBrowse link
toll-like receptor TLR1:TLR2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:51,772,635...51,794,107
Ensembl chr12:51,773,448...51,794,104 		JBrowse link
toll-like receptor TLR6:TLR2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:22,976,951...22,979,568
Ensembl chr13:22,966,137...22,983,109 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469 		JBrowse link
G TLR2 toll like receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,993...75,428,330 		JBrowse link
G TLR6 toll like receptor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:30,159,744...30,180,650
Ensembl chr 8:30,159,754...30,180,650 		JBrowse link
TRAM-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKCE protein kinase C epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:94,351,277...94,864,549
Ensembl chr 3:94,349,889...94,866,306 		JBrowse link
G RAB11FIP2 RAB11 family interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:128,068,085...128,110,949
Ensembl chr14:128,068,959...128,110,512 		JBrowse link
G TICAM2 toll like receptor adaptor molecule 2 involved_in ISO (PMID:19412184)
(PMID:22685567)		 UniProt PMID:19412184 PMID:22685567 NCBI chr 2:119,758,622...119,778,650 JBrowse link
TRIF-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD274 CD274 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:216,646,378...216,792,731
Ensembl chr 1:216,660,041...216,792,724 		JBrowse link
G CD300LF CD300 molecule like family member f involved_in ISO (PMID:22043923) UniProt PMID:22043923 NCBI chr12:6,501,151...6,521,135 JBrowse link
G IRF3 interferon regulatory factor 3 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:54,701,733...54,706,079
Ensembl chr 6:54,701,668...54,707,151 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in IEA
IBA		 Ensembl
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:74,004,566...74,021,100
Ensembl chr 2:74,004,308...74,021,873 		JBrowse link
G TICAM2 toll like receptor adaptor molecule 2 involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 2:119,758,622...119,778,650 JBrowse link
G TLR4 toll like receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISO (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chr 8:30,159,744...30,180,650
Ensembl chr 8:30,159,754...30,180,650 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17668
    immune system process 2525
      activation of immune response 519
        activation of innate immune response 296
          induced systemic resistance, ethylene mediated signaling pathway 0
          induced systemic resistance, jasmonic acid mediated signaling pathway 0
          innate immune response-activating signaling pathway + 274
Path 2
Term Annotations click to browse term
  biological_process 17668
    response to stimulus 10007
      response to external stimulus 2557
        response to external biotic stimulus 1689
          response to other organism 1685
            defense response to other organism 1163
              defense response to symbiont 954
                innate immune response 879
                  regulation of innate immune response 442
                    positive regulation of innate immune response 360
                      activation of innate immune response 296
                        induced systemic resistance, ethylene mediated signaling pathway 0
                        induced systemic resistance, jasmonic acid mediated signaling pathway 0
                        innate immune response-activating signaling pathway + 274
paths to the root