LOC733579 (tripartite motif protein TRIM5) - Rat Genome Database

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Gene: LOC733579 (tripartite motif protein TRIM5) Sus scrofa
Analyze
Symbol: LOC733579 (Ensembl: TRIM22)
Name: tripartite motif protein TRIM5 (Ensembl:tripartite motif containing 22)
RGD ID: 14057286
Description: ENCODES a protein that exhibits identical protein binding (ortholog); pattern recognition receptor activity (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN activation of innate immune response (ortholog); negative regulation of viral entry into host cell (ortholog); positive regulation of MAPK cascade (ortholog); ASSOCIATED WITH genetic disease (ortholog); human immunodeficiency virus infectious disease (ortholog); prostate cancer (ortholog); FOUND IN omegasome (ortholog); P-body (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl94,157,290 - 4,170,204 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.194,157,290 - 4,170,233 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.294,724,246 - 4,737,190 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074  


Genomics

Comparative Map Data
LOC733579
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl94,157,290 - 4,170,204 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.194,157,290 - 4,170,233 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.294,724,246 - 4,737,190 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRIM5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38115,588,635 - 5,685,074 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl115,663,195 - 5,938,619 (-)EnsemblGRCh38hg38GRCh38
GRCh37115,684,425 - 5,706,304 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36115,641,364 - 5,662,869 (-)NCBINCBI36Build 36hg18NCBI36
Build 34115,641,368 - 5,662,869NCBI
Celera115,803,483 - 5,825,436 (-)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef115,344,050 - 5,365,972 (-)NCBIHuRef
CHM1_1115,683,377 - 5,705,274 (-)NCBICHM1_1
T2T-CHM13v2.0115,647,845 - 5,742,931 (-)NCBIT2T-CHM13v2.0
Trim5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397103,912,593 - 103,937,448 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7103,912,593 - 103,937,301 (-)EnsemblGRCm39 Ensembl
GRCm387104,263,386 - 104,288,254 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7104,263,386 - 104,288,094 (-)EnsemblGRCm38mm10GRCm38
MGSCv377111,413,000 - 111,436,646 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367104,137,205 - 104,162,054 (-)NCBIMGSCv36mm8
Celera7104,635,824 - 104,653,489 (-)NCBICelera
Cytogenetic Map7E3NCBI
cM Map755.69NCBI
Trim5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81168,132,277 - 168,149,263 (-)NCBIGRCr8
mRatBN7.21158,720,407 - 158,737,393 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1158,720,410 - 158,814,012 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1166,708,173 - 166,725,110 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01173,888,188 - 173,905,126 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01166,780,756 - 166,797,732 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01169,446,774 - 169,463,760 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1169,446,805 - 169,534,896 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01175,586,814 - 175,603,800 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41162,096,439 - 162,113,409 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11162,190,323 - 162,207,293 (-)NCBI
Celera1156,710,957 - 156,727,926 (-)NCBICelera
Cytogenetic Map1q32NCBI
TRIM5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v298,083,611 - 8,123,913 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1118,041,285 - 8,081,595 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0115,798,336 - 5,819,876 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1115,479,033 - 5,754,014 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl115,479,033 - 5,500,758 (-)Ensemblpanpan1.1panPan2
TRIM5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1161,040,908 - 61,067,815 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl161,040,928 - 61,069,356 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604364,938,737 - 64,966,441 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in LOC733579
517 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 9 2 1 5 1 2 3
Low 1 2 2 2 22 2 1
Below cutoff

Sequence


RefSeq Acc Id: ENSSSCT00000016021   ⟹   ENSSSCP00000015599
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl94,157,294 - 4,170,205 (-)Ensembl
RefSeq Acc Id: NM_001044532   ⟹   NP_001037997
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.194,157,290 - 4,170,233 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001037997 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAY40468 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000015599.4
  ENSSSCP00005040705.1
  ENSSSCP00015043568.1
  ENSSSCP00025006120.1
  ENSSSCP00045038958.1
  ENSSSCP00055008868.1
  ENSSSCP00070000129.1
RefSeq Acc Id: NP_001037997   ⟸   NM_001044532
- UniProtKB: Q3MJK4 (UniProtKB/TrEMBL),   A0A8D0KBG7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000015599   ⟸   ENSSSCT00000016021
Protein Domains
B box-type   B30.2/SPRY   RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000014670 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00005041009 UniProtKB/TrEMBL
  ENSSSCG00015077157 UniProtKB/TrEMBL
  ENSSSCG00025011729 UniProtKB/TrEMBL
  ENSSSCG00045032711 UniProtKB/TrEMBL
  ENSSSCG00055005775 UniProtKB/TrEMBL
  ENSSSCG00070000109 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000016021.6 UniProtKB/TrEMBL
  ENSSSCT00005065784.1 UniProtKB/TrEMBL
  ENSSSCT00015104253.1 UniProtKB/TrEMBL
  ENSSSCT00025015490.1 UniProtKB/TrEMBL
  ENSSSCT00045055885.1 UniProtKB/TrEMBL
  ENSSSCT00055011230.1 UniProtKB/TrEMBL
  ENSSSCT00070000162.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/TrEMBL
  Butyrophylin_SPRY UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/TrEMBL
  SPRY_dom UniProtKB/TrEMBL
  Znf-RING_LisH UniProtKB/TrEMBL
  Znf_B-box UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report ssc:733579 UniProtKB/TrEMBL
NCBI Gene LOC733579 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE TRIM UniProtKB/TrEMBL
  PTHR24103:SF416 UniProtKB/TrEMBL
Pfam SPRY UniProtKB/TrEMBL
  zf-B_box UniProtKB/TrEMBL
  zf-RING_UBOX UniProtKB/TrEMBL
PRINTS BUTYPHLNCDUF UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/TrEMBL
  ZF_BBOX UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART BBOX UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
Superfamily-SCOP B-box zinc-binding domain UniProtKB/TrEMBL
  RING/U-box UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
UniProt A0A4X1SEB3_PIG UniProtKB/TrEMBL
  A0A8D0KBG7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0QB61_PIG UniProtKB/TrEMBL
  A0A8D1IZ74_PIG UniProtKB/TrEMBL
  A0A8D1PSL0_PIG UniProtKB/TrEMBL
  F1RLV7_PIG UniProtKB/TrEMBL
  Q3MJK4 ENTREZGENE, UniProtKB/TrEMBL