PELI1 (pellino E3 ubiquitin protein ligase 1) - Rat Genome Database

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Gene: PELI1 (pellino E3 ubiquitin protein ligase 1) Sus scrofa
Analyze
Symbol: PELI1
Name: pellino E3 ubiquitin protein ligase 1
RGD ID: 14178857
Description: ENCODES a protein that exhibits transferase activity (inferred); ubiquitin protein ligase activity (inferred); ubiquitin-protein transferase activity (inferred); INVOLVED IN negative regulation of NF-kappaB transcription factor activity (ortholog); negative regulation of T cell activation (ortholog); negative regulation of T cell proliferation (ortholog); PARTICIPATES IN interleukin-1 signaling pathway; ASSOCIATED WITH Arsenic Poisoning (ortholog); Bardet-Biedl syndrome (ortholog); colorectal cancer (ortholog); FOUND IN site of double-strand break (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase pellino homolog 1; pellino homolog 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl377,713,489 - 77,796,914 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1377,740,460 - 77,796,911 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PELI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl377,713,489 - 77,796,914 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1377,740,460 - 77,796,911 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PELI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38264,092,652 - 64,144,420 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl264,092,652 - 64,144,420 (-)EnsemblGRCh38hg38GRCh38
GRCh37264,319,786 - 64,371,554 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36264,173,499 - 64,192,987 (-)NCBINCBI36Build 36hg18NCBI36
Build 34264,231,645 - 64,251,134NCBI
Celera264,165,044 - 64,216,871 (-)NCBICelera
Cytogenetic Map2p14NCBI
HuRef264,059,563 - 64,111,396 (-)NCBIHuRef
CHM1_1264,250,026 - 64,301,844 (-)NCBICHM1_1
T2T-CHM13v2.0264,100,282 - 64,152,062 (-)NCBIT2T-CHM13v2.0
Peli1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391121,041,283 - 21,100,327 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1121,041,291 - 21,100,323 (+)EnsemblGRCm39 Ensembl
GRCm381121,091,283 - 21,150,327 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1121,091,291 - 21,150,323 (+)EnsemblGRCm38mm10GRCm38
MGSCv371120,991,327 - 21,050,330 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361121,035,472 - 21,050,326 (+)NCBIMGSCv36mm8
Celera1123,239,549 - 23,298,574 (+)NCBICelera
Cytogenetic Map11A3.1NCBI
cM Map1113.81NCBI
Peli1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81499,455,970 - 99,510,474 (+)NCBIGRCr8
mRatBN7.21495,254,274 - 95,309,168 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1495,254,589 - 95,308,285 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1499,600,859 - 99,654,628 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014100,841,202 - 100,894,967 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01497,314,719 - 97,368,484 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014106,008,086 - 106,062,566 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14106,008,086 - 106,061,641 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014106,075,061 - 106,128,271 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414101,870,272 - 101,924,228 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.114101,920,929 - 101,943,454 (+)NCBI
Celera1494,267,696 - 94,321,536 (+)NCBICelera
Cytogenetic Map14q22NCBI
Peli1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542420,211,600 - 20,263,761 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542420,212,077 - 20,263,761 (+)NCBIChiLan1.0ChiLan1.0
PELI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21262,250,630 - 62,306,758 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A62,257,658 - 62,310,709 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A64,160,362 - 64,213,200 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A65,284,472 - 65,336,335 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A65,284,480 - 65,336,339 (-)Ensemblpanpan1.1panPan2
PELI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11063,727,905 - 63,863,599 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1063,729,604 - 63,743,303 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1063,616,694 - 63,752,371 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01064,736,541 - 64,872,342 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1064,736,553 - 64,795,619 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11064,418,361 - 64,554,038 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01064,727,691 - 64,863,369 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01065,019,832 - 65,155,570 (-)NCBIUU_Cfam_GSD_1.0
Peli1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629219,530,464 - 19,586,021 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364918,985,074 - 9,041,244 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364918,985,074 - 9,040,863 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PELI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11442,864,857 - 42,930,315 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1442,864,897 - 42,930,394 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604568,937,787 - 69,003,497 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Peli1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247629,328,109 - 9,386,067 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247629,328,275 - 9,382,996 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PELI1
934 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000009160   ⟹   ENSSSCP00000008929
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl377,658,664 - 77,796,884 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000028590   ⟹   ENSSSCP00000026040
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl377,740,484 - 77,796,914 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000040046   ⟹   ENSSSCP00000050408
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl377,713,489 - 77,796,906 (+)Ensembl
RefSeq Acc Id: XM_021087454   ⟹   XP_020943113
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1377,740,460 - 77,796,911 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021087455   ⟹   XP_020943114
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1377,764,768 - 77,796,911 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021087456   ⟹   XP_020943115
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1377,740,472 - 77,796,911 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020943113 (Get FASTA)   NCBI Sequence Viewer  
  XP_020943114 (Get FASTA)   NCBI Sequence Viewer  
  XP_020943115 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000026040
  ENSSSCP00000026040.3
  ENSSSCP00000050408
  ENSSSCP00000050408.1
  ENSSSCP00005036586.1
  ENSSSCP00005036594.1
  ENSSSCP00005036598.1
  ENSSSCP00005036602.1
  ENSSSCP00005036619.1
  ENSSSCP00005036625.1
  ENSSSCP00015004622.1
  ENSSSCP00015004642.1
  ENSSSCP00015004677.1
  ENSSSCP00025046119.1
  ENSSSCP00025046132.1
  ENSSSCP00025046149.1
  ENSSSCP00030023538.1
  ENSSSCP00030023543.1
  ENSSSCP00030023557.1
  ENSSSCP00035046897.1
  ENSSSCP00035046931.1
  ENSSSCP00040046128.1
  ENSSSCP00040046182.1
  ENSSSCP00045022858.1
  ENSSSCP00045022895.1
  ENSSSCP00045022934.1
  ENSSSCP00050043286.1
  ENSSSCP00050043288.1
  ENSSSCP00055045758.1
  ENSSSCP00055045784.1
  ENSSSCP00055045809.1
  ENSSSCP00055045839.1
  ENSSSCP00055045871.1
  ENSSSCP00055045899.1
  ENSSSCP00055045922.1
  ENSSSCP00055045947.1
  ENSSSCP00055045982.1
  ENSSSCP00055045995.1
  ENSSSCP00060025217.1
  ENSSSCP00060025225.1
  ENSSSCP00065011929.1
  ENSSSCP00065011931.1
  ENSSSCP00065011933.1
  ENSSSCP00065011935.1
  ENSSSCP00065011937.1
  ENSSSCP00065011940.1
  ENSSSCP00065011944.1
  ENSSSCP00065011949.1
  ENSSSCP00065011954.1
  ENSSSCP00065011958.1
  ENSSSCP00070051533.1
  ENSSSCP00070051539.1
  ENSSSCP00070051544.1
RefSeq Acc Id: XP_020943113   ⟸   XM_021087454
- UniProtKB: A0A480ULK7 (UniProtKB/TrEMBL),   A0A4X1WC74 (UniProtKB/TrEMBL),   A0A8D1HSN0 (UniProtKB/TrEMBL),   A0A8D1XX62 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020943115   ⟸   XM_021087456
- UniProtKB: A0A480ULK7 (UniProtKB/TrEMBL),   A0A4X1WC74 (UniProtKB/TrEMBL),   A0A8D1HSN0 (UniProtKB/TrEMBL),   A0A8D1XX62 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020943114   ⟸   XM_021087455
- UniProtKB: A0A480ULK7 (UniProtKB/TrEMBL),   A0A4X1WC74 (UniProtKB/TrEMBL),   A0A8D1HSN0 (UniProtKB/TrEMBL),   A0A8D1XX62 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000050408   ⟸   ENSSSCT00000040046
Ensembl Acc Id: ENSSSCP00000008929   ⟸   ENSSSCT00000009160
Ensembl Acc Id: ENSSSCP00000026040   ⟸   ENSSSCT00000028590
Protein Domains
Pellino FHA   Pellino RING


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000028947 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005037104 UniProtKB/TrEMBL
  ENSSSCG00015008884 UniProtKB/TrEMBL
  ENSSSCG00025075387 UniProtKB/TrEMBL
  ENSSSCG00030037168 UniProtKB/TrEMBL
  ENSSSCG00035079235 UniProtKB/TrEMBL
  ENSSSCG00040073969 UniProtKB/TrEMBL
  ENSSSCG00045019375 UniProtKB/TrEMBL
  ENSSSCG00050073153 UniProtKB/TrEMBL
  ENSSSCG00055028836 UniProtKB/TrEMBL
  ENSSSCG00060043423 UniProtKB/TrEMBL
  ENSSSCG00065021971 UniProtKB/TrEMBL
  ENSSSCG00070030081 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000028590 ENTREZGENE
  ENSSSCT00000028590.4 UniProtKB/TrEMBL
  ENSSSCT00000040046 ENTREZGENE
  ENSSSCT00000040046.3 UniProtKB/TrEMBL
  ENSSSCT00005059248.1 UniProtKB/TrEMBL
  ENSSSCT00005059270.1 UniProtKB/TrEMBL
  ENSSSCT00005059280.1 UniProtKB/TrEMBL
  ENSSSCT00005059285.1 UniProtKB/TrEMBL
  ENSSSCT00005059309.1 UniProtKB/TrEMBL
  ENSSSCT00005059316.1 UniProtKB/TrEMBL
  ENSSSCT00015011724.1 UniProtKB/TrEMBL
  ENSSSCT00015011763.1 UniProtKB/TrEMBL
  ENSSSCT00015011842.1 UniProtKB/TrEMBL
  ENSSSCT00025103950.1 UniProtKB/TrEMBL
  ENSSSCT00025103978.1 UniProtKB/TrEMBL
  ENSSSCT00025104010.1 UniProtKB/TrEMBL
  ENSSSCT00030051689.1 UniProtKB/TrEMBL
  ENSSSCT00030051699.1 UniProtKB/TrEMBL
  ENSSSCT00030051718.1 UniProtKB/TrEMBL
  ENSSSCT00035108282.1 UniProtKB/TrEMBL
  ENSSSCT00035108347.1 UniProtKB/TrEMBL
  ENSSSCT00040102187.1 UniProtKB/TrEMBL
  ENSSSCT00040102266.1 UniProtKB/TrEMBL
  ENSSSCT00045032968.1 UniProtKB/TrEMBL
  ENSSSCT00045033029.1 UniProtKB/TrEMBL
  ENSSSCT00045033089.1 UniProtKB/TrEMBL
  ENSSSCT00050099937.1 UniProtKB/TrEMBL
  ENSSSCT00050099940.1 UniProtKB/TrEMBL
  ENSSSCT00055057200.1 UniProtKB/TrEMBL
  ENSSSCT00055057228.1 UniProtKB/TrEMBL
  ENSSSCT00055057258.1 UniProtKB/TrEMBL
  ENSSSCT00055057297.1 UniProtKB/TrEMBL
  ENSSSCT00055057340.1 UniProtKB/TrEMBL
  ENSSSCT00055057373.1 UniProtKB/TrEMBL
  ENSSSCT00055057397.1 UniProtKB/TrEMBL
  ENSSSCT00055057426.1 UniProtKB/TrEMBL
  ENSSSCT00055057470.1 UniProtKB/TrEMBL
  ENSSSCT00055057484.1 UniProtKB/TrEMBL
  ENSSSCT00060058889.1 UniProtKB/TrEMBL
  ENSSSCT00060058903.1 UniProtKB/TrEMBL
  ENSSSCT00065029226.1 UniProtKB/TrEMBL
  ENSSSCT00065029233.1 UniProtKB/TrEMBL
  ENSSSCT00065029238.1 UniProtKB/TrEMBL
  ENSSSCT00065029240.1 UniProtKB/TrEMBL
  ENSSSCT00065029244.1 UniProtKB/TrEMBL
  ENSSSCT00065029247.1 UniProtKB/TrEMBL
  ENSSSCT00065029253.1 UniProtKB/TrEMBL
  ENSSSCT00065029260.1 UniProtKB/TrEMBL
  ENSSSCT00065029266.1 UniProtKB/TrEMBL
  ENSSSCT00065029270.1 UniProtKB/TrEMBL
  ENSSSCT00070060480.1 UniProtKB/TrEMBL
  ENSSSCT00070060487.1 UniProtKB/TrEMBL
  ENSSSCT00070060492.1 UniProtKB/TrEMBL
InterPro Pellino_fam UniProtKB/TrEMBL
  Pellino_FHA UniProtKB/TrEMBL
  Pellino_RING UniProtKB/TrEMBL
NCBI Gene PELI1 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE PELLINO HOMOLOG 1 UniProtKB/TrEMBL
  PTHR12098 UniProtKB/TrEMBL
Pfam Pellino UniProtKB/TrEMBL
  Pellino_RING UniProtKB/TrEMBL
PIRSF Pellino UniProtKB/TrEMBL
UniProt A0A480ULK7 ENTREZGENE
  A0A4X1WC74 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1WC78_PIG UniProtKB/TrEMBL
  A0A8D0WMM7_PIG UniProtKB/TrEMBL
  A0A8D1BN06_PIG UniProtKB/TrEMBL
  A0A8D1HSN0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1XX62 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A480ULK7 UniProtKB/TrEMBL
  I3LPL3 UniProtKB/TrEMBL
VGNC ID VGNC:91306 ENTREZGENE