SLC15A4 (solute carrier family 15 member 4) - Rat Genome Database

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Gene: SLC15A4 (solute carrier family 15 member 4) Sus scrofa
Analyze
Symbol: SLC15A4
Name: solute carrier family 15 member 4
RGD ID: 13895580
Description: ENCODES a protein that exhibits L-histidine transmembrane transporter activity (ortholog); INVOLVED IN histidine transport (ortholog); ASSOCIATED WITH systemic lupus erythematosus (ortholog); FOUND IN early endosome membrane (inferred); endolysosome membrane (inferred); endosome membrane (inferred)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: PHT1; PTR4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1426,122,386 - 26,154,781 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11426,122,362 - 26,154,414 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21427,770,845 - 27,803,186 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC15A4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1426,122,386 - 26,154,781 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11426,122,362 - 26,154,414 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21427,770,845 - 27,803,186 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC15A4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812128,793,194 - 128,823,958 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12128,793,194 - 128,823,958 (-)EnsemblGRCh38hg38GRCh38
GRCh3712129,277,739 - 129,308,503 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612127,843,713 - 127,874,494 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412127,802,644 - 127,833,421NCBI
Celera12128,891,861 - 128,922,740 (-)NCBICelera
Cytogenetic Map12q24.33NCBI
HuRef12126,263,573 - 126,285,425 (-)NCBIHuRef
CHM1_112129,098,609 - 129,129,417 (-)NCBICHM1_1
T2T-CHM13v2.012128,825,188 - 128,855,979 (-)NCBIT2T-CHM13v2.0
Slc15a4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395127,668,795 - 127,710,356 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5127,672,728 - 127,709,961 (-)EnsemblGRCm39 Ensembl
GRCm385127,594,545 - 127,633,292 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5127,595,664 - 127,632,897 (-)EnsemblGRCm38mm10GRCm38
MGSCv375128,076,036 - 128,097,762 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365127,884,869 - 127,906,595 (-)NCBIMGSCv36mm8
Celera5124,625,149 - 124,646,865 (-)NCBICelera
Cytogenetic Map5G1.2NCBI
cM Map566.0NCBI
Slc15a4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81234,684,583 - 34,718,429 (+)NCBIGRCr8
mRatBN7.21229,048,634 - 29,082,480 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1229,063,015 - 29,082,480 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1230,198,626 - 30,218,177 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01230,810,079 - 30,829,630 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01229,869,246 - 29,888,797 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01232,753,824 - 32,773,277 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1232,753,824 - 32,773,277 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01234,660,965 - 34,680,418 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41230,111,863 - 30,131,134 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11229,975,250 - 29,994,522 (+)NCBI
Celera1230,749,254 - 30,768,706 (+)NCBICelera
Cytogenetic Map12q14NCBI
Slc15a4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554822,327,137 - 2,343,980 (+)NCBIChiLan1.0ChiLan1.0
SLC15A4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210136,865,833 - 136,896,753 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112136,862,353 - 136,893,242 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012126,418,071 - 126,448,917 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112130,639,525 - 130,669,822 (-)NCBIpanpan1.1PanPan1.1panPan2
SLC15A4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1262,803,798 - 2,832,057 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl262,802,724 - 2,831,530 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha263,006,941 - 3,035,199 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0263,056,487 - 3,084,750 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl263,056,499 - 3,084,223 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1262,988,152 - 3,015,703 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0263,086,221 - 3,113,814 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0262,996,157 - 3,024,420 (+)NCBIUU_Cfam_GSD_1.0
Slc15a4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118124,227,513 - 124,239,308 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936660481,772 - 493,567 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC15A4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111124,170,785 - 124,204,358 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11124,169,732 - 124,204,200 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037121,090,609 - 121,123,572 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc15a4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474726,252,492 - 26,275,173 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474726,252,788 - 26,275,273 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC15A4
862 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000031300   ⟹   ENSSSCP00000022255
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1426,122,386 - 26,154,781 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000044442   ⟹   ENSSSCP00000056497
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1426,122,363 - 26,153,521 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000106968   ⟹   ENSSSCP00000081381
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1426,122,387 - 26,154,416 (+)Ensembl
RefSeq Acc Id: NM_001315736   ⟹   NP_001302665
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11426,122,363 - 26,153,383 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003359076   ⟹   XP_003359124
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11426,122,362 - 26,154,414 (+)NCBI
Sequence:
RefSeq Acc Id: XP_003359124   ⟸   XM_003359076
- Peptide Label: isoform X1
- UniProtKB: A0A8D1ZMG7 (UniProtKB/TrEMBL),   W6D6F4 (UniProtKB/TrEMBL),   I3LDX0 (UniProtKB/TrEMBL),   A0A480YD76 (UniProtKB/TrEMBL),   A0A8D1RFT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001302665   ⟸   NM_001315736
- UniProtKB: I3LDX0 (UniProtKB/TrEMBL),   A0A8D1ZMG7 (UniProtKB/TrEMBL),   W6D6F4 (UniProtKB/TrEMBL),   A0A480YD76 (UniProtKB/TrEMBL),   A0A8D1RFT4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000056497   ⟸   ENSSSCT00000044442
Ensembl Acc Id: ENSSSCP00000022255   ⟸   ENSSSCT00000031300
Ensembl Acc Id: ENSSSCP00000081381   ⟸   ENSSSCT00000106968


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000025820 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015030761 UniProtKB/TrEMBL
  ENSSSCG00025045128 UniProtKB/TrEMBL
  ENSSSCG00030035439 UniProtKB/TrEMBL
  ENSSSCG00035051984 UniProtKB/TrEMBL
  ENSSSCG00040009516 UniProtKB/TrEMBL
  ENSSSCG00045031290 UniProtKB/TrEMBL
  ENSSSCG00055021873 UniProtKB/TrEMBL
  ENSSSCG00060030648 UniProtKB/TrEMBL
  ENSSSCG00065061305 UniProtKB/TrEMBL
  ENSSSCG00070018675 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000031300 ENTREZGENE
  ENSSSCT00000031300.4 UniProtKB/TrEMBL
  ENSSSCT00015040952.1 UniProtKB/TrEMBL
  ENSSSCT00025061385.1 UniProtKB/TrEMBL
  ENSSSCT00030049187.1 UniProtKB/TrEMBL
  ENSSSCT00035069285.1 UniProtKB/TrEMBL
  ENSSSCT00040012341.1 UniProtKB/TrEMBL
  ENSSSCT00045053419.1 UniProtKB/TrEMBL
  ENSSSCT00055043120.1 UniProtKB/TrEMBL
  ENSSSCT00060041421.1 UniProtKB/TrEMBL
  ENSSSCT00065083993.1 UniProtKB/TrEMBL
  ENSSSCT00070036820.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.20 UniProtKB/TrEMBL
InterPro MFS_trans_sf UniProtKB/TrEMBL
  POT_fam UniProtKB/TrEMBL
  PTR2_symporter_CS UniProtKB/TrEMBL
KEGG Report ssc:100623262 UniProtKB/TrEMBL
NCBI Gene SLC15A4 ENTREZGENE
PANTHER PTHR11654 UniProtKB/TrEMBL
  SOLUTE CARRIER FAMILY 15 MEMBER 4 UniProtKB/TrEMBL
Pfam PTR2 UniProtKB/TrEMBL
PROSITE PTR2_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF103473 UniProtKB/TrEMBL
UniProt A0A480YD76 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1UL43_PIG UniProtKB/TrEMBL
  A0A8D1RFT4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1ZMG7 ENTREZGENE, UniProtKB/TrEMBL
  I3LDX0 ENTREZGENE, UniProtKB/TrEMBL
  W6D6F4 ENTREZGENE
UniProt Secondary W6D6F4 UniProtKB/TrEMBL
VGNC ID VGNC:92937 ENTREZGENE