LYPLAL1 (lysophospholipase like 1) - Rat Genome Database

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Gene: LYPLAL1 (lysophospholipase like 1) Sus scrofa
Analyze
Symbol: LYPLAL1
Name: lysophospholipase like 1
RGD ID: 13991284
Description: ENCODES a protein that exhibits hydrolase activity (inferred); INVOLVED IN negative regulation of Golgi to plasma membrane protein transport (ortholog); protein depalmitoylation (ortholog); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); Holt-Oram syndrome (ortholog); Loeys-Dietz syndrome 4 (ortholog); FOUND IN cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: lysophospholipase-like protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl108,946,487 - 9,062,412 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1108,946,463 - 9,061,033 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21011,029,585 - 11,088,269 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
cytosol  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:14681463  


Genomics

Comparative Map Data
LYPLAL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl108,946,487 - 9,062,412 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1108,946,463 - 9,061,033 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21011,029,585 - 11,088,269 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LYPLAL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1219,173,869 - 219,212,865 (+)EnsemblGRCh38hg38GRCh38
GRCh381219,173,850 - 219,445,121 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371219,347,220 - 219,386,200 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361217,413,844 - 217,451,783 (+)NCBINCBI36hg18NCBI36
Build 341215,735,617 - 215,773,553NCBI
Celera1192,564,906 - 192,603,940 (+)NCBI
Cytogenetic Map1q41NCBI
HuRef1190,016,930 - 190,055,957 (+)NCBIHuRef
CHM1_11220,620,005 - 220,659,032 (+)NCBICHM1_1
Lyplal1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391185,819,929 - 185,849,507 (-)NCBIGRCm39mm39
GRCm39 Ensembl1185,819,928 - 185,849,507 (-)Ensembl
GRCm381186,087,732 - 186,117,310 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1186,087,731 - 186,117,310 (-)EnsemblGRCm38mm10GRCm38
MGSCv371187,911,611 - 187,941,189 (-)NCBIGRCm37mm9NCBIm37
MGSCv361187,788,668 - 187,818,098 (-)NCBImm8
Celera1193,030,160 - 193,053,254 (-)NCBICelera
Cytogenetic Map1H5NCBI
Lyplal1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21397,626,451 - 97,657,901 (-)NCBI
Rnor_6.0 Ensembl13104,049,386 - 104,080,631 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.013104,049,263 - 104,080,680 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.013108,706,787 - 108,738,098 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413102,143,174 - 102,171,752 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.113102,332,339 - 102,360,879 (-)NCBI
Celera1397,136,739 - 97,168,192 (-)NCBICelera
Cytogenetic Map13q26NCBI
Lyplal1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555204,251,957 - 4,281,838 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555204,251,863 - 4,281,775 (-)NCBIChiLan1.0ChiLan1.0
LYPLAL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11199,586,920 - 199,625,423 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1199,586,920 - 199,625,423 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01194,737,158 - 194,775,853 (+)NCBIMhudiblu_PPA_v0panPan3
LYPLAL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13814,100,818 - 14,137,292 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3814,100,698 - 14,268,481 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3814,143,532 - 14,180,609 (+)NCBI
ROS_Cfam_1.03814,136,744 - 14,173,896 (+)NCBI
UMICH_Zoey_3.13814,146,280 - 14,183,361 (+)NCBI
UNSW_CanFamBas_1.03814,489,895 - 14,526,974 (+)NCBI
UU_Cfam_GSD_1.03814,802,107 - 14,838,748 (+)NCBI
Lyplal1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934457,685,177 - 57,712,354 (-)NCBI
SpeTri2.0NW_0049366502,933,661 - 2,960,558 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LYPLAL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12510,370,715 - 10,408,807 (-)NCBI
ChlSab1.1 Ensembl2510,370,814 - 10,408,767 (-)Ensembl
Vero_WHO_p1.0NW_02366605510,766,878 - 10,806,116 (-)NCBI
Lyplal1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248353,023,151 - 3,052,826 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2
Low 10 4 3 5 2 23 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000011834   ⟹   ENSSSCP00000011531
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl108,946,493 - 9,014,498 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000044181   ⟹   ENSSSCP00000031863
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl108,946,505 - 9,005,289 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000045494   ⟹   ENSSSCP00000033069
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl108,946,492 - 9,014,498 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000066526   ⟹   ENSSSCP00000067691
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl108,946,487 - 9,018,581 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000088357   ⟹   ENSSSCP00000062453
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl108,946,505 - 9,062,412 (+)Ensembl
RefSeq Acc Id: XM_021064301   ⟹   XP_020919960
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1108,946,463 - 9,013,831 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021064302   ⟹   XP_020919961
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1108,946,465 - 8,978,533 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021064303   ⟹   XP_020919962
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1108,946,464 - 9,061,033 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021064304   ⟹   XP_020919963
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1108,946,464 - 9,016,357 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021064305   ⟹   XP_020919964
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1108,946,464 - 9,052,205 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_020919960   ⟸   XM_021064301
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020919962   ⟸   XM_021064303
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_020919964   ⟸   XM_021064305
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_020919963   ⟸   XM_021064304
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_020919961   ⟸   XM_021064302
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSSSCP00000062453   ⟸   ENSSSCT00000088357
RefSeq Acc Id: ENSSSCP00000031863   ⟸   ENSSSCT00000044181
RefSeq Acc Id: ENSSSCP00000011531   ⟸   ENSSSCT00000011834
RefSeq Acc Id: ENSSSCP00000033069   ⟸   ENSSSCT00000045494
RefSeq Acc Id: ENSSSCP00000067691   ⟸   ENSSSCT00000066526
Protein Domains
Abhydrolase_2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000010817 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070011324 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000011531 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000031863 UniProtKB/TrEMBL
  ENSSSCP00000033069 UniProtKB/TrEMBL
  ENSSSCP00000062453 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000067691 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070018273 UniProtKB/TrEMBL
  ENSSSCP00070018277 UniProtKB/TrEMBL
  ENSSSCP00070018284 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000011834 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000044181 UniProtKB/TrEMBL
  ENSSSCT00000045494 UniProtKB/TrEMBL
  ENSSSCT00000066526 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000088357 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070022060 UniProtKB/TrEMBL
  ENSSSCT00070022063 UniProtKB/TrEMBL
  ENSSSCT00070022074 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  PLipase/COase/thioEstase UniProtKB/TrEMBL
NCBI Gene LYPLAL1 ENTREZGENE
Pfam Abhydrolase_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A0A286ZJU8_PIG UniProtKB/TrEMBL
  A0A286ZNB8_PIG UniProtKB/TrEMBL
  A0A480K5P1_PIG UniProtKB/TrEMBL
  A0A4X1TMU7_PIG UniProtKB/TrEMBL
  A0A4X1TPY6_PIG UniProtKB/TrEMBL
  A0A4X1TSH2_PIG UniProtKB/TrEMBL
  A0A5G2R0G4_PIG UniProtKB/TrEMBL
  F1S9K9_PIG UniProtKB/TrEMBL
VGNC ID VGNC:95939 ENTREZGENE