HSP90AA1 (heat shock protein 90 alpha family class A member 1)

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Gene: HSP90AA1 (heat shock protein 90 alpha family class A member 1) Sus scrofa

Analyze

Symbol:

HSP90AA1

Name:

heat shock protein 90 alpha family class A member 1

RGD ID:

13936954

Description:

ENCODES a protein that exhibits ATP binding (ortholog); CTP binding (ortholog); dATP binding (ortholog); INVOLVED IN activation of innate immune response (ortholog); cardiac muscle cell apoptotic process (ortholog); cellular response to virus (ortholog); PARTICIPATES IN aldosterone signaling pathway; androgen signaling pathway; chaperone mediated autophagy pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); anaplastic large cell lymphoma (ortholog); Breast Neoplasms (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); brush border membrane (ortholog); INTERACTS WITH glutathione; paraquat

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

90-kDa heat shock protein; heat shock protein HSP 90-alpha; HSP90; HSP90A; Hspca

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa10.2	7	129,758,754 - 129,760,542 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

anaplastic large cell lymphoma (ISO)

Breast Neoplasms (ISO)

Charcot-Marie-Tooth disease axonal type 2O (ISO)

Cognitive Dysfunction (ISO)

colon cancer (ISO)

contact dermatitis (ISO)

Ductal Carcinoma (ISO)

Experimental Diabetes Mellitus (ISO)

Frontotemporal Lobar Degeneration (ISO)

genetic disease (ISO)

human immunodeficiency virus infectious disease (ISO)

intrahepatic cholangiocarcinoma (ISO)

Knee Osteoarthritis (ISO)

Neoplasm Metastasis (ISO)

Neurodevelopmental Disorders (ISO)

portal hypertension (ISO)

rheumatoid arthritis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

glutathione (EXP)

paraquat (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

activation of innate immune response (IEA,ISS)

cardiac muscle cell apoptotic process (ISO)

cellular response to heat (IBA,IEA)

cellular response to virus (IEA,ISS)

chaperone-mediated protein complex assembly (IEA)

neuron migration (ISO)

positive regulation of cardiac muscle contraction (ISO)

positive regulation of cell size (ISO)

positive regulation of defense response to virus by host (IEA,ISS)

positive regulation of interferon-beta production (IEA,ISS)

positive regulation of lamellipodium assembly (ISO)

positive regulation of nitric oxide biosynthetic process (IEA,ISS)

positive regulation of protein catabolic process (IEA)

positive regulation of protein import into nucleus (ISO)

positive regulation of protein phosphorylation (IEA)

positive regulation of protein polymerization (IEA)

protein folding (IBA,IEA)

protein insertion into mitochondrial outer membrane (IEA)

protein stabilization (IBA,IEA)

regulation of apoptotic process (IEA,ISS)

regulation of postsynaptic membrane neurotransmitter receptor levels (ISO)

regulation of protein localization (IEA)

regulation of protein ubiquitination (IEA)

response to antibiotic (ISS)

response to cocaine (ISO)

response to cold (ISS)

response to estrogen (ISO)

response to heat (ISS)

response to salt stress (ISO)

response to xenobiotic stimulus (ISO)

skeletal muscle contraction (ISO)

telomerase holoenzyme complex assembly (IEA)

telomere maintenance via telomerase (IEA)

Cellular Component

apical plasma membrane (ISO)

axonal growth cone (IEA)

basolateral plasma membrane (ISO)

brush border membrane (ISO)

cell surface (ISO)

collagen-containing extracellular matrix (ISO)

cytoplasm (IEA,ISS)

cytosol (IBA,IEA)

dendritic growth cone (IEA)

melanosome (IEA)

membrane (IEA)

mitochondrion (IEA,ISS)

myelin sheath (IBA,ISO)

neuronal cell body (IBA,IEA,ISO)

nucleoplasm (IEA)

nucleus (IBA,IEA,ISS)

perinuclear region of cytoplasm (IBA,IEA,ISO)

plasma membrane (IBA,IEA)

protein-containing complex (IBA,IEA,ISO)

ruffle membrane (ISO)

sperm flagellum (ISO)

sperm mitochondrial sheath (ISO)

sperm plasma membrane (ISO)

Molecular Function

ATP binding (IBA,IEA,ISO,ISS)

ATP hydrolysis activity (IEA)

ATP-dependent protein folding chaperone (IEA)

CTP binding (ISO)

dATP binding (ISO)

disordered domain specific binding (IBA,IEA)

DNA polymerase binding (IEA)

GTP binding (ISO)

GTPase binding (IEA)

histone deacetylase binding (IEA)

hydrolase activity (IEA)

identical protein binding (IEA)

mRNA binding (ISO)

nitric-oxide synthase regulator activity (IEA,ISS)

nucleotide binding (IEA)

protein binding (ISO)

protein folding chaperone (IEA)

protein homodimerization activity (IEA)

protein phosphatase binding (ISO)

protein tyrosine kinase binding (IEA)

Rho GDP-dissociation inhibitor binding (ISO)

scaffold protein binding (IEA)

sulfonylurea receptor binding (ISO)

tau protein binding (IEA,ISO)

TPR domain binding (IEA,ISS)

transmembrane transporter binding (ISO)

ubiquitin protein ligase binding (IEA)

unfolded protein binding (IBA,IEA)

UTP binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

aldosterone signaling pathway (ISO)

androgen signaling pathway (ISO)

chaperone mediated autophagy pathway (ISO)

cortisol signaling pathway (ISO)

epidermal growth factor/neuregulin signaling pathway (ISO)

estrogen signaling pathway (ISO)

phosphatidylinositol 3-kinase class I signaling pathway (ISO)

phosphatidylinositol 3-kinase-Akt signaling pathway (ISO)

prednisolone pharmacodynamics pathway (ISO)

prednisolone pharmacokinetics pathway (ISO)

protein kinase C (PKC) signaling pathway (ISO)

vascular endothelial growth factor signaling pathway (ISO)

References

Additional References at PubMed

PMID:8751722	PMID:9931505	PMID:14681463	PMID:17145712	PMID:17337508	PMID:18215117	PMID:19293389	PMID:20580074	PMID:20693398	PMID:22301074	PMID:27264891	PMID:27553861
PMID:29935435	PMID:30032202	PMID:33242760

Genomics

Comparative Map Data

HSP90AA1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa10.2	7	129,758,754 - 129,760,542 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HSP90AA1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	102,080,742 - 102,139,749 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	102,080,742 - 102,139,699 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	102,547,079 - 102,606,086 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	101,616,828 - 101,675,839 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	101,617,144 - 101,623,135	NCBI
Celera	14	82,601,564 - 82,660,582 (-)	NCBI		Celera
Cytogenetic Map	14	q32.31	NCBI
HuRef	14	82,725,979 - 82,785,051 (-)	NCBI		HuRef
CHM1_1	14	102,484,935 - 102,543,941 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	14	96,316,329 - 96,375,332 (-)	NCBI		T2T-CHM13v2.0

Hsp90aa1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	110,657,470 - 110,662,829 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	110,657,039 - 110,669,162 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	110,691,036 - 110,696,395 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	110,690,605 - 110,702,728 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	111,929,246 - 111,934,605 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	111,138,843 - 111,144,202 (-)	NCBI		MGSCv36	mm8
Celera	12	111,881,002 - 111,886,365 (-)	NCBI		Celera
Cytogenetic Map	12	F1	NCBI
cM Map	12	60.75	NCBI

Hsp90aa1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	6	129,702,376 - 129,707,907 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	129,702,383 - 129,707,268 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	129,879,675 - 129,884,976 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	130,175,668 - 130,180,969 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	129,539,256 - 129,544,788 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	135,107,262 - 135,112,793 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	135,107,271 - 135,112,775 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	6	135,045,363 - 135,049,728 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	144,182,009 - 144,187,540 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	135,413,616 - 135,419,147 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	135,419,806 - 135,425,334 (-)	NCBI
Celera	6	127,272,361 - 127,277,892 (-)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

Hsp90aa1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955538	1,469,544 - 1,475,019 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955538	1,469,544 - 1,475,010 (-)	NCBI	ChiLan1.0	ChiLan1.0

HSP90AA1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	14	102,449,856 - 102,456,012 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	82,700,881 - 82,707,020 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	102,519,033 - 102,524,639 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	102,519,699 - 102,576,723 (-)	Ensembl	panpan1.1		panPan2

HSP90AA1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	70,091,203 - 70,096,107 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	70,092,217 - 70,095,243 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	69,605,578 - 69,611,507 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	70,369,324 - 70,375,263 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	70,369,667 - 70,374,704 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	70,033,441 - 70,039,369 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	70,098,797 - 70,104,717 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	70,498,429 - 70,504,357 (-)	NCBI		UU_Cfam_GSD_1.0

Hsp90aa1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	3,873,950 - 3,879,144 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936835	316,767 - 321,990 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936835	316,767 - 321,999 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HSP90AA1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	80,016,352 - 80,019,130 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	80,016,232 - 80,019,120 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	67,207,536 - 67,213,629 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hsp90aa1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	2,233,547 - 2,241,436 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	2,233,932 - 2,239,687 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium	10	4	3	5	2	23	2	3	3
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_213973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000452	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK234540	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK237363	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK240418	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK350245	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK392141	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK392876	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK398738	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU633632	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01038446	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U94395	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Protein Sequences


Protein RefSeqs	NP_999138	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC48718	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000002743.5
	ENSSSCP00000046159
	ENSSSCP00000046159.2
	ENSSSCP00000052402.3
	ENSSSCP00015005536.1
	ENSSSCP00025015057.1
	ENSSSCP00025015120.1
	ENSSSCP00025015195
	ENSSSCP00030023822.1
	ENSSSCP00030023836.1
	ENSSSCP00030023862
	ENSSSCP00035030973.1
	ENSSSCP00035030977.1
	ENSSSCP00040047983
	ENSSSCP00045010690.1
	ENSSSCP00045010734.1
	ENSSSCP00050000902.1
	ENSSSCP00050000909.1
	ENSSSCP00050000939
	ENSSSCP00055031606.1
	ENSSSCP00060004146.1
	ENSSSCP00065043662.1
	ENSSSCP00065043667
	ENSSSCP00070017984.1
	ENSSSCP00070017989.1
	ENSSSCP00070017996
	ENSSSCP00070018014.1
	ENSSSCP00070018018.1
GenBank Protein	O02705	(Get FASTA)	NCBI Sequence Viewer

Protein Domains

Histidine kinase/HSP90-like ATPase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000002535	ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00015010858	UniProtKB/TrEMBL
	ENSSSCG00025026657	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSSSCG00030037509	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSSSCG00035056819	UniProtKB/TrEMBL
	ENSSSCG00040075632	UniProtKB/Swiss-Prot
	ENSSSCG00045009069	UniProtKB/TrEMBL
	ENSSSCG00050002300	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSSSCG00055020126	UniProtKB/TrEMBL
	ENSSSCG00060008700	UniProtKB/TrEMBL
	ENSSSCG00065071916	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSSSCG00070011114	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000002815.5	UniProtKB/TrEMBL
	ENSSSCT00000045247.3	UniProtKB/TrEMBL
	ENSSSCT00000058545	ENTREZGENE
	ENSSSCT00000058545.3	UniProtKB/TrEMBL
	ENSSSCT00015014249.1	UniProtKB/TrEMBL
	ENSSSCT00025036060.1	UniProtKB/TrEMBL
	ENSSSCT00025036188.1	UniProtKB/TrEMBL
	ENSSSCT00025036343	UniProtKB/Swiss-Prot
	ENSSSCT00030052204.1	UniProtKB/TrEMBL
	ENSSSCT00030052232.1	UniProtKB/TrEMBL
	ENSSSCT00030052297	UniProtKB/Swiss-Prot
	ENSSSCT00035075945.1	UniProtKB/TrEMBL
	ENSSSCT00035075951.1	UniProtKB/TrEMBL
	ENSSSCT00040105032	UniProtKB/Swiss-Prot
	ENSSSCT00045015387.1	UniProtKB/TrEMBL
	ENSSSCT00045015453.1	UniProtKB/TrEMBL
	ENSSSCT00050002846.1	UniProtKB/TrEMBL
	ENSSSCT00050002867.1	UniProtKB/TrEMBL
	ENSSSCT00050002917	UniProtKB/Swiss-Prot
	ENSSSCT00055039731.1	UniProtKB/TrEMBL
	ENSSSCT00060011169.1	UniProtKB/TrEMBL
	ENSSSCT00065099486.1	UniProtKB/TrEMBL
	ENSSSCT00065099496	UniProtKB/Swiss-Prot
	ENSSSCT00070021734.1	UniProtKB/TrEMBL
	ENSSSCT00070021740.1	UniProtKB/TrEMBL
	ENSSSCT00070021746	UniProtKB/Swiss-Prot
	ENSSSCT00070021764.1	UniProtKB/TrEMBL
	ENSSSCT00070021768.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.120.790	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.30.230.80	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.30.565.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.40.50.11260	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	HATPase_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	HATPase_C_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Heat_shock_protein_90_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	HSP90_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Hsp90_fam	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Hsp90_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ribosomal_S5_D2-typ_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	ssc:397028	UniProtKB/Swiss-Prot
NCBI Gene	HSP90AA1	ENTREZGENE
PANTHER	HEAT SHOCK PROTEIN HSP 90-ALPHA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR11528	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	HATPase_c	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	HSP90	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF	Hsp90	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	HEATSHOCK90	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	HSP90	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	HATPase_c	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF110942	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF54211	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF55874	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A287AQK7_PIG	UniProtKB/TrEMBL
	A0A287B8J5_PIG	UniProtKB/TrEMBL
	A0A4X1TM49_PIG	UniProtKB/TrEMBL
	A0A4X1TS03_PIG	UniProtKB/TrEMBL
	A0A4X1TS11_PIG	UniProtKB/TrEMBL
	A0A4X1TS37_PIG	UniProtKB/TrEMBL
	A0A8D1R9S0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I8C3K7_PIG	UniProtKB/TrEMBL
	HS90A_PIG	UniProtKB/Swiss-Prot, ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - PID (archival)