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Gene: PLCG2 (phospholipase C gamma 2) Sus scrofa
Symbol: PLCG2
Name: phospholipase C gamma 2
RGD ID: 14108637
Description: ENCODES a protein that exhibits phosphatidylinositol phospholipase C activity (inferred); phosphorylation-dependent protein binding (inferred); phosphotyrosine residue binding (inferred); INVOLVED IN B cell differentiation (ortholog); positive regulation of cytosolic calcium ion concentration (ortholog); regulation of gene expression (ortholog); PARTICIPATES IN erythropoietin signaling pathway; phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Autoinflammation, Antibody Deficiency, and Immune Dysregulation, PLCG2-Associated (ortholog); B-Cell Chronic Lymphocytic Leukemia (ortholog); FOUND IN membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
Homo sapiens (human) : PLCG2 (phospholipase C gamma 2)  HGNC  Alliance
Mus musculus (house mouse) : Plcg2 (phospholipase C, gamma 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Plcg2 (phospholipase C, gamma 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plcg2 (phospholipase C gamma 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PLCG2 (phospholipase C gamma 2)
Canis lupus familiaris (dog) : PLCG2 (phospholipase C gamma 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plcg2 (phospholipase C gamma 2)
Chlorocebus sabaeus (African green monkey) : PLCG2 (phospholipase C gamma 2)
Heterocephalus glaber (naked mole-rat) : Plcg2 (phospholipase C gamma 2)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl66,433,153 - 6,603,060 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.166,433,146 - 6,603,092 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.266,994,243 - 7,071,019 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated


Comparative Map Data


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on PLCG2
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 14108637
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2020-07-01
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.