Plcg2 (phospholipase C gamma 2) - Rat Genome Database
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Gene: Plcg2 (phospholipase C gamma 2) Chinchilla lanigera
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Symbol: Plcg2
Name: phospholipase C gamma 2
RGD ID: 8709179
Description: ENCODES a protein that exhibits phosphatidylinositol phospholipase C activity (ortholog); phosphorylation-dependent protein binding (ortholog); phosphotyrosine residue binding (ortholog); INVOLVED IN activation of store-operated calcium channel activity (ortholog); B cell differentiation (ortholog); B cell receptor signaling pathway (ortholog); PARTICIPATES IN erythropoietin signaling pathway; phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Autoinflammation, Antibody Deficiency, and Immune Dysregulation, PLCG2-Associated (ortholog); B-Cell Chronic Lymphocytic Leukemia (ortholog); FOUND IN cytosol (ortholog); membrane (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; phospholipase C, gamma 2 (phosphatidylinositol-specific)
Orthologs:
Homo sapiens (human) : PLCG2 (phospholipase C gamma 2)  HGNC  Alliance
Mus musculus (house mouse) : Plcg2 (phospholipase C, gamma 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Plcg2 (phospholipase C, gamma 2)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : PLCG2 (phospholipase C gamma 2)
Canis lupus familiaris (dog) : PLCG2 (phospholipase C gamma 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plcg2 (phospholipase C gamma 2)
Sus scrofa (pig) : PLCG2 (phospholipase C gamma 2)
Chlorocebus sabaeus (African green monkey) : PLCG2 (phospholipase C gamma 2)
Heterocephalus glaber (naked mole-rat) : Plcg2 (phospholipase C gamma 2)
more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555224,358,233 - 4,468,986 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555224,352,890 - 4,480,735 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Plcg2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555224,358,233 - 4,468,986 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555224,352,890 - 4,480,735 (+)NCBIChiLan1.0ChiLan1.0
PLCG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1681,739,097 - 81,962,685 (+)EnsemblGRCh38hg38GRCh38
GRCh381681,779,291 - 81,962,685 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371681,812,899 - 81,996,290 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361680,362,768 - 80,549,400 (+)NCBINCBI36hg18NCBI36
Build 341680,370,430 - 80,549,399NCBI
Celera1666,110,768 - 66,289,752 (+)NCBI
Cytogenetic Map16q23.3NCBI
HuRef1667,566,775 - 67,745,459 (+)NCBIHuRef
CHM1_11683,224,217 - 83,407,660 (+)NCBICHM1_1
Plcg2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398118,225,014 - 118,361,881 (+)NCBI
GRCm388117,498,275 - 117,635,142 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8117,498,291 - 117,635,142 (+)EnsemblGRCm38mm10GRCm38
MGSCv378120,022,191 - 120,159,042 (+)NCBIGRCm37mm9NCBIm37
MGSCv368120,384,268 - 120,521,119 (+)NCBImm8
Celera8121,718,712 - 121,856,018 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map864.26NCBI
Plcg2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01950,039,410 - 50,173,543 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1950,045,020 - 50,173,220 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01960,828,451 - 60,962,641 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41947,875,572 - 47,947,573 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11947,880,452 - 47,952,454 (-)NCBI
Celera1944,819,007 - 44,954,904 (+)NCBICelera
Cytogenetic Map19q12NCBI
RH 3.4 Map19609.8RGD
PLCG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11681,812,581 - 81,984,067 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1681,812,565 - 81,984,064 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01662,383,270 - 62,561,579 (+)NCBIMhudiblu_PPA_v0panPan3
PLCG2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl570,059,255 - 70,207,049 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1570,054,683 - 70,233,459 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Plcg2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493647529,248,533 - 29,377,335 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLCG2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl66,433,153 - 6,603,060 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.166,433,146 - 6,603,092 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.266,994,243 - 7,071,019 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLCG2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl567,215,459 - 67,398,990 (+)Ensembl
ChlSab1.1567,209,268 - 67,394,865 (+)NCBI
Plcg2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247465,678,057 - 5,824,663 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000000788   ⟹   ENSCLAP00000000752
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555224,358,233 - 4,468,986 (+)Ensembl
RefSeq Acc Id: XM_013507097   ⟹   XP_013362551
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555224,352,890 - 4,480,735 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013362551 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013362551   ⟸   XM_013507097
- Sequence:
RefSeq Acc Id: ENSCLAP00000000752   ⟸   ENSCLAT00000000788


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000000592 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000000752 ENTREZGENE
Ensembl Transcript ENSCLAT00000000788 ENTREZGENE
NCBI Gene Plcg2 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Plcg2  phospholipase C gamma 2    phospholipase C, gamma 2 (phosphatidylinositol-specific)  Symbol and/or name change 5135510 APPROVED