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Gene: Plcg2 (phospholipase C gamma 2) Ictidomys tridecemlineatus
Symbol: Plcg2
Name: phospholipase C gamma 2
RGD ID: 12737388
Description: ENCODES a protein that exhibits phosphatidylinositol phospholipase C activity (ortholog); phosphorylation-dependent protein binding (ortholog); phosphotyrosine residue binding (ortholog); INVOLVED IN activation of store-operated calcium channel activity (ortholog); B cell differentiation (ortholog); B cell receptor signaling pathway (ortholog); PARTICIPATES IN erythropoietin signaling pathway; phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Autoinflammation, Antibody Deficiency, and Immune Dysregulation, PLCG2-Associated (ortholog); B-Cell Chronic Lymphocytic Leukemia (ortholog); FOUND IN cytosol (ortholog); membrane (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
Homo sapiens (human) : PLCG2 (phospholipase C gamma 2)  HGNC  Alliance
Mus musculus (house mouse) : Plcg2 (phospholipase C, gamma 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Plcg2 (phospholipase C, gamma 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plcg2 (phospholipase C gamma 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PLCG2 (phospholipase C gamma 2)
Canis lupus familiaris (dog) : PLCG2 (phospholipase C gamma 2)
Sus scrofa (pig) : PLCG2 (phospholipase C gamma 2)
Chlorocebus sabaeus (African green monkey) : PLCG2 (phospholipase C gamma 2)
Heterocephalus glaber (naked mole-rat) : Plcg2 (phospholipase C gamma 2)
more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
SpeTri2.0NW_00493647529,248,533 - 29,377,335 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations


Comparative Map Data



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Plcg2
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 12737388
Created: 2017-01-27
Species: Ictidomys tridecemlineatus
Last Modified: 2020-08-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.