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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:cyfluthrin
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Accession:CHEBI:4034 term browser browse the term
Definition:A carboxylic ester obtained by formal condensation between 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid and (4-fluoro-3-phenoxyphenyl)(hydroxy)acetonitrile.
Synonyms:exact_synonym: cyano(4-fluoro-3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
 related_synonym: (R,S)-alpha-Cyano-4-fluoro-3-phenoxybenzyl-(1R,S)-cis,trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate;   Formula=C22H18Cl2FNO3;   InChI=1S/C22H18Cl2FNO3/c1-22(2)15(11-19(23)24)20(22)21(27)29-18(12-26)13-8-9-16(25)17(10-13)28-14-6-4-3-5-7-14/h3-11,15,18,20H,1-2H3;   InChIKey=QQODLKZGRKWIFG-UHFFFAOYSA-N;   SMILES=CC1(C)C(C=C(Cl)Cl)C1C(=O)OC(C#N)c1ccc(F)c(Oc2ccccc2)c1
 xref: Beilstein:2788149;   CAS:68359-37-5;   Drug_Central:4407;   KEGG:C10982;   KEGG:D07761
 xref_mesh: MESH:C052570
 xref: PMID:17912691;   PMID:18383791;   PPDB:192;   Patent:DE2709264;   Patent:US4218469;   Patent:US4287208;   Reaxys:2788149


show annotations for term's descendants           Sort by:
cyfluthrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Yt blood group) decreases activity ISO cyfluthrin results in decreased activity of ACHE protein CTD PMID:26604153 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions
increases expression		 EXP Melatonin inhibits the reaction [cyfluthrin results in increased expression of AKT1 mRNA] CTD PMID:31330490 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G ALB albumin decreases expression
multiple interactions		 ISO cyfluthrin results in decreased expression of ALB protein
basil oil inhibits the reaction [cyfluthrin results in decreased expression of ALB protein]; Oils, Volatile inhibits the reaction [cyfluthrin results in decreased expression of ALB protein]		 CTD PMID:35126122 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G AOX1 aldehyde oxidase 1 increases expression
multiple interactions		 EXP cyfluthrin results in increased expression of AOX1 mRNA
Melatonin inhibits the reaction [cyfluthrin results in increased expression of AOX1 mRNA]		 CTD PMID:31330490 NCBI chr 2:200,586,014...200,682,241
Ensembl chr 2:200,586,014...200,677,064 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 increases expression EXP cyfluthrin results in increased expression of APAF1 mRNA CTD PMID:31330490 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,149...98,735,433 		JBrowse link
G AR androgen receptor decreases activity
multiple interactions		 EXP cyfluthrin results in decreased activity of AR protein
cyfluthrin binds to and results in increased activity of AR protein; Dihydrotestosterone inhibits the reaction [cyfluthrin results in increased activity of AR protein]		 CTD PMID:15064155 PMID:20410157 PMID:33049310 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G ATF4 activating transcription factor 4 increases expression ISO cyfluthrin results in increased expression of ATF4 mRNA; cyfluthrin results in increased expression of ATF4 protein CTD PMID:36548566 NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683 		JBrowse link
G ATOX1 antioxidant 1 copper chaperone decreases expression EXP cyfluthrin results in decreased expression of ATOX1 mRNA CTD PMID:31330490 NCBI chr 5:151,742,822...151,758,631
Ensembl chr 5:151,742,316...151,772,532 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 EXP cyfluthrin results in increased expression of BAX mRNA
Melatonin inhibits the reaction [cyfluthrin results in increased expression of BAX mRNA]		 CTD PMID:31330490 PMID:32028016 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator increases expression EXP cyfluthrin results in increased expression of BCL2 mRNA CTD PMID:31330490 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCR BCR activator of RhoGEF and GTPase increases expression EXP cyfluthrin results in increased expression of BCR protein CTD PMID:16790487 NCBI chr22:23,180,509...23,318,037
Ensembl chr22:23,179,704...23,318,037 		JBrowse link
G BDNF brain derived neurotrophic factor increases expression ISO cyfluthrin results in increased expression of BDNF mRNA CTD PMID:16166269 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BNIP3 BCL2 interacting protein 3 multiple interactions
increases expression		 EXP Melatonin inhibits the reaction [cyfluthrin results in increased expression of BNIP3 mRNA] CTD PMID:31330490 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967 		JBrowse link
G CAMK2A calcium/calmodulin dependent protein kinase II alpha increases expression EXP cyfluthrin results in increased expression of CAMK2A mRNA CTD PMID:32028016 NCBI chr 5:150,219,491...150,290,130
Ensembl chr 5:150,219,491...150,290,093 		JBrowse link
G CAMK2B calcium/calmodulin dependent protein kinase II beta increases expression EXP cyfluthrin results in increased expression of CAMK2B mRNA CTD PMID:32028016 NCBI chr 7:44,217,154...44,326,013
Ensembl chr 7:44,210,019...44,334,577 		JBrowse link
G CASP3 caspase 3 increases expression
multiple interactions		 EXP cyfluthrin results in increased expression of CASP3 mRNA
Melatonin inhibits the reaction [cyfluthrin results in increased expression of CASP3 mRNA]		 CTD PMID:31330490 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CAT catalase decreases activity
decreases expression
affects binding
multiple interactions		 EXP
ISO		 cyfluthrin results in decreased activity of CAT protein
cyfluthrin results in decreased expression of CAT mRNA
cyfluthrin binds to CAT protein
cyfluthrin results in decreased expression of CAT protein
basil oil inhibits the reaction [cyfluthrin results in decreased activity of CAT protein]; Oils, Volatile inhibits the reaction [cyfluthrin results in decreased activity of CAT protein]; Selenium inhibits the reaction [cyfluthrin results in decreased activity of CAT protein]
[Melatonin co-treated with cyfluthrin] results in increased activity of CAT protein; Melatonin inhibits the reaction [cyfluthrin results in decreased activity of CAT protein]; N-acetylserotonin inhibits the reaction [cyfluthrin results in decreased activity of CAT protein]		 CTD PMID:19961921 PMID:23595963 PMID:26604153 PMID:31330490 PMID:32278787 More... NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 multiple interactions
increases expression		 EXP Melatonin inhibits the reaction [cyfluthrin results in increased expression of CCL5 mRNA] CTD PMID:31330490 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CES2 carboxylesterase 2 increases metabolic processing EXP CES2 protein results in increased metabolism of cyfluthrin CTD PMID:19249324 NCBI chr16:66,934,471...66,945,096
Ensembl chr16:66,934,444...66,945,096 		JBrowse link
G CHAT choline O-acetyltransferase decreases expression ISO cyfluthrin results in decreased expression of CHAT protein CTD PMID:26604153 NCBI chr10:49,609,095...49,667,942
Ensembl chr10:49,609,095...49,667,942 		JBrowse link
G CLIP3 CAP-Gly domain containing linker protein 3 increases expression EXP cyfluthrin results in increased expression of CLIP3 protein CTD PMID:16790487 NCBI chr19:36,014,660...36,032,873
Ensembl chr19:36,014,660...36,033,343 		JBrowse link
G CYBB cytochrome b-245 beta chain multiple interactions
increases expression		 EXP Melatonin inhibits the reaction [cyfluthrin results in increased expression of CYBB mRNA] CTD PMID:31330490 NCBI chr  X:37,780,059...37,813,461
Ensembl chr  X:37,780,018...37,813,461 		JBrowse link
G CYGB cytoglobin decreases expression EXP cyfluthrin results in decreased expression of CYGB mRNA CTD PMID:31330490 NCBI chr17:76,527,356...76,551,193
Ensembl chr17:76,527,356...76,551,175 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 increases activity ISO cyfluthrin results in increased activity of CYP2E1 protein CTD PMID:23639246 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 increases expression EXP cyfluthrin results in increased expression of CYP3A4 mRNA CTD PMID:19249324 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression ISO cyfluthrin results in increased expression of DDIT3 mRNA; cyfluthrin results in increased expression of DDIT3 protein CTD PMID:36548566 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G DUOX1 dual oxidase 1 increases expression EXP cyfluthrin results in increased expression of DUOX1 mRNA CTD PMID:31330490 NCBI chr15:45,129,994...45,165,574
Ensembl chr15:45,129,933...45,165,576 		JBrowse link
G DUOX2 dual oxidase 2 increases expression EXP cyfluthrin results in increased expression of DUOX2 mRNA CTD PMID:31330490 NCBI chr15:45,092,650...45,114,172
Ensembl chr15:45,092,650...45,114,172 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation
increases expression		 ISO cyfluthrin results in increased phosphorylation of EIF2AK3 protein
cyfluthrin results in increased expression of EIF2AK3 mRNA		 CTD PMID:36548566 NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha increases expression
increases phosphorylation		 ISO cyfluthrin results in increased expression of EIF2S1 mRNA
cyfluthrin results in increased phosphorylation of EIF2S1 protein		 CTD PMID:36548566 NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516 		JBrowse link
G EPHX2 epoxide hydrolase 2 decreases expression EXP cyfluthrin results in decreased expression of EPHX2 mRNA CTD PMID:31330490 NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564 		JBrowse link
G ESR1 estrogen receptor 1 increases activity
multiple interactions
decreases activity		 EXP
ISO		 cyfluthrin results in increased activity of ESR1 protein
cyfluthrin binds to and results in increased activity of ESR1 protein
cyfluthrin results in decreased activity of ESR1 protein		 CTD PMID:15064155 PMID:20410157 PMID:33049310 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 increases expression ISO cyfluthrin results in increased expression of FLT1 protein CTD PMID:36548566 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145 		JBrowse link
G FTH1 ferritin heavy chain 1 decreases expression EXP cyfluthrin results in decreased expression of FTH1 mRNA CTD PMID:31330490 NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634 		JBrowse link
G GAP43 growth associated protein 43 increases expression EXP cyfluthrin results in increased expression of GAP43 mRNA CTD PMID:32028016 NCBI chr 3:115,623,510...115,721,483
Ensembl chr 3:115,623,510...115,721,490 		JBrowse link
G GLA galactosidase alpha decreases expression EXP cyfluthrin results in decreased expression of GLA mRNA CTD PMID:31330490 NCBI chr  X:101,397,803...101,407,925
Ensembl chr  X:101,393,273...101,408,012 		JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions
affects activity		 ISO basil oil affects the reaction [cyfluthrin affects the activity of GPT protein]; Oils, Volatile affects the reaction [cyfluthrin affects the activity of GPT protein] CTD PMID:35126122 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G GPX1 glutathione peroxidase 1 decreases expression EXP cyfluthrin results in decreased expression of GPX1 mRNA CTD PMID:31330490 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GPX2 glutathione peroxidase 2 decreases expression EXP cyfluthrin results in decreased expression of GPX2 mRNA CTD PMID:31330490 NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746 		JBrowse link
G GPX3 glutathione peroxidase 3 decreases expression EXP cyfluthrin results in decreased expression of GPX3 mRNA CTD PMID:31330490 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
G GSR glutathione-disulfide reductase multiple interactions
decreases expression
decreases activity		 ISO
EXP		 basil oil inhibits the reaction [cyfluthrin results in decreased activity of GSR protein]; Oils, Volatile inhibits the reaction [cyfluthrin results in decreased activity of GSR protein]; Selenium inhibits the reaction [cyfluthrin results in decreased activity of GSR protein]
cyfluthrin results in decreased expression of GSR mRNA		 CTD PMID:23595963 PMID:31330490 PMID:35126122 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846 		JBrowse link
G GSTZ1 glutathione S-transferase zeta 1 decreases expression EXP cyfluthrin results in decreased expression of GSTZ1 mRNA CTD PMID:31330490 NCBI chr14:77,321,036...77,331,597
Ensembl chr14:77,320,996...77,331,597 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 increases expression EXP cyfluthrin results in increased expression of HSP90AA1 mRNA CTD PMID:31330490 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A multiple interactions
increases expression		 EXP Melatonin inhibits the reaction [cyfluthrin results in increased expression of HSPA1A mRNA] CTD PMID:31330490 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression ISO cyfluthrin results in increased expression of HSPA5 mRNA; cyfluthrin results in increased expression of HSPA5 protein CTD PMID:36548566 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HYDIN HYDIN axonemal central pair apparatus protein decreases expression EXP cyfluthrin results in decreased expression of HYDIN protein CTD PMID:16790487 NCBI chr16:70,802,084...71,230,722
Ensembl chr16:70,802,084...71,230,722 		JBrowse link
G IFNG interferon gamma multiple interactions EXP cyfluthrin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IFNG protein] CTD PMID:12755381 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL4 interleukin 4 multiple interactions EXP cyfluthrin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL4 protein] CTD PMID:12755381 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL6 interleukin 6 increases expression
multiple interactions		 EXP
ISO		 cyfluthrin results in increased expression of IL6 protein
basil oil inhibits the reaction [cyfluthrin results in increased expression of IL6 mRNA]; Oils, Volatile inhibits the reaction [cyfluthrin results in increased expression of IL6 mRNA]
cyfluthrin results in increased expression of IL6 mRNA; cyfluthrin results in increased expression of IL6 protein		 CTD PMID:16790487 PMID:35126122 PMID:36515635 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha increases expression ISO cyfluthrin results in increased expression of MAP1LC3A mRNA CTD PMID:36515635 NCBI chr20:34,546,844...34,560,345
Ensembl chr20:34,546,854...34,560,345 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases expression EXP cyfluthrin results in increased expression of MAPK1 protein CTD PMID:16790487 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases expression EXP cyfluthrin results in increased expression of MAPK3 protein CTD PMID:16790487 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MTOR mechanistic target of rapamycin kinase increases expression
decreases expression		 ISO cyfluthrin results in increased expression of MTOR mRNA; cyfluthrin results in increased expression of MTOR protein
cyfluthrin results in decreased expression of MTOR protein modified form		 CTD PMID:36515635 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G NEFH neurofilament heavy chain increases expression EXP cyfluthrin results in increased expression of NEFH mRNA CTD PMID:32028016 NCBI chr22:29,480,218...29,491,390
Ensembl chr22:29,480,218...29,491,390 		JBrowse link
G NEFL neurofilament light chain decreases expression EXP cyfluthrin results in decreased expression of NEFL mRNA CTD PMID:32028016 NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,956,721 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions		 EXP cyfluthrin results in increased expression of NFE2L2 mRNA
Melatonin inhibits the reaction [cyfluthrin results in increased expression of NFE2L2 mRNA]		 CTD PMID:31330490 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 increases expression EXP cyfluthrin results in increased expression of NFKB1 mRNA CTD PMID:31330490 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions
increases expression		 EXP Melatonin inhibits the reaction [cyfluthrin results in increased expression of NOS2 mRNA] CTD PMID:31330490 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOX5 NADPH oxidase 5 increases expression
multiple interactions		 EXP cyfluthrin results in increased expression of NOX5 mRNA
Melatonin inhibits the reaction [cyfluthrin results in increased expression of NOX5 mRNA]		 CTD PMID:31330490 NCBI chr15:68,930,525...69,062,762
Ensembl chr15:69,014,695...69,062,762
Ensembl chr15:69,014,695...69,062,762 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 increases expression
decreases activity
multiple interactions		 EXP cyfluthrin results in increased expression of NQO1 mRNA
cyfluthrin results in decreased activity of NQO1 protein
Melatonin inhibits the reaction [cyfluthrin results in decreased activity of NQO1 protein]; Melatonin inhibits the reaction [cyfluthrin results in increased expression of NQO1 mRNA]; Silybin inhibits the reaction [cyfluthrin results in decreased activity of NQO1 protein]		 CTD PMID:31330490 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 multiple interactions EXP cyfluthrin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 increases activity
multiple interactions		 ISO
EXP		 cyfluthrin results in increased activity of NR1I2 protein
cyfluthrin results in increased activity of NR1I2 protein; cyfluthrin results in increased activity of NR1I2 protein polymorphism
cyfluthrin binds to and results in increased activity of NR1I2 protein		 CTD PMID:19249324 PMID:21115097 PMID:22206814 PMID:33049310 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487 		JBrowse link
G PCNA proliferating cell nuclear antigen decreases expression ISO cyfluthrin results in decreased expression of PCNA protein CTD PMID:36548566 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626 		JBrowse link
G PGF placental growth factor decreases expression ISO cyfluthrin results in decreased expression of PGF protein CTD PMID:36548566 NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626 		JBrowse link
G PGR progesterone receptor affects binding EXP cyfluthrin binds to PGR protein CTD PMID:32278787 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3 increases expression EXP cyfluthrin results in increased expression of PIK3C3 mRNA CTD PMID:32028016 NCBI chr18:41,955,234...42,087,830
Ensembl chr18:41,955,234...42,087,830 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions ISO
EXP		 cyfluthrin binds to and results in increased activity of PPARG protein CTD PMID:33049310 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPP2R3B protein phosphatase 2 regulatory subunit B''beta increases expression EXP cyfluthrin results in increased expression of PPP2R3B protein CTD PMID:16790487 NCBI chr  X:333,933...386,907
NCBI chr  Y:333,933...386,907
Ensembl chr  Y:333,933...386,955
Ensembl chr  X:333,933...386,955 		JBrowse link
G PRDX2 peroxiredoxin 2 decreases expression EXP cyfluthrin results in decreased expression of PRDX2 mRNA CTD PMID:31330490 NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800 		JBrowse link
G PRDX4 peroxiredoxin 4 decreases expression EXP cyfluthrin results in decreased expression of PRDX4 mRNA CTD PMID:31330490 NCBI chr  X:23,667,493...23,686,397
Ensembl chr  X:23,664,262...23,686,397 		JBrowse link
G PRDX5 peroxiredoxin 5 decreases expression EXP cyfluthrin results in decreased expression of PRDX5 mRNA CTD PMID:31330490 NCBI chr11:64,318,121...64,321,811
Ensembl chr11:64,318,121...64,321,811 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 decreases expression ISO cyfluthrin results in decreased expression of PRKAA1 mRNA CTD PMID:36515635 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 decreases expression ISO cyfluthrin results in decreased expression of PRKAA2 mRNA CTD PMID:36515635 NCBI chr 1:56,645,314...56,715,335
Ensembl chr 1:56,645,314...56,715,335 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 decreases expression EXP cyfluthrin results in decreased expression of PTGS1 mRNA CTD PMID:31330490 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 increases expression EXP cyfluthrin results in increased expression of PTGS2 mRNA CTD PMID:31330490 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 decreases expression
increases expression		 ISO cyfluthrin results in decreased expression of RPS6KB1 protein modified form
cyfluthrin results in increased expression of RPS6KB1 mRNA; cyfluthrin results in increased expression of RPS6KB1 protein		 CTD PMID:36515635 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 multiple interactions
affects activity		 ISO cyfluthrin affects the reaction [SCN10A protein results in increased transport of Sodium]
cyfluthrin affects the activity of SCN10A protein		 CTD PMID:16051293 PMID:19766671 NCBI chr 3:38,696,807...38,816,217
Ensembl chr 3:38,696,802...38,816,286 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 multiple interactions ISO cyfluthrin affects the reaction [[SCN2A protein binds to SCN1B protein] which results in increased transport of Sodium] CTD PMID:18538810 NCBI chr19:35,030,470...35,040,449
Ensembl chr19:35,030,470...35,040,449 		JBrowse link
G SCN2A sodium voltage-gated channel alpha subunit 2 multiple interactions ISO cyfluthrin affects the reaction [[SCN2A protein binds to SCN1B protein] which results in increased transport of Sodium] CTD PMID:18538810 NCBI chr 2:165,239,414...165,392,304
Ensembl chr 2:165,194,993...165,392,310 		JBrowse link
G SCN3A sodium voltage-gated channel alpha subunit 3 multiple interactions ISO cyfluthrin affects the reaction [[SCN3A protein binds to SCN3B protein] which results in increased transport of Sodium] CTD PMID:18538810 NCBI chr 2:165,087,526...165,204,050
Ensembl chr 2:165,087,526...165,204,050 		JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 multiple interactions ISO cyfluthrin affects the reaction [[SCN3A protein binds to SCN3B protein] which results in increased transport of Sodium] CTD PMID:18538810 NCBI chr11:123,629,188...123,654,624
Ensembl chr11:123,629,187...123,655,244 		JBrowse link
G SLC6A14 solute carrier family 6 member 14 decreases expression EXP cyfluthrin results in decreased expression of SLC6A14 protein CTD PMID:16790487 NCBI chr  X:116,436,606...116,461,458
Ensembl chr  X:116,436,606...116,461,458 		JBrowse link
G SOD2 superoxide dismutase 2 decreases expression EXP cyfluthrin results in decreased expression of SOD2 mRNA CTD PMID:31330490 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SQSTM1 sequestosome 1 increases expression
decreases expression
multiple interactions		 EXP
ISO		 cyfluthrin results in increased expression of SQSTM1 mRNA
cyfluthrin results in decreased expression of SQSTM1 mRNA; cyfluthrin results in decreased expression of SQSTM1 protein
Melatonin inhibits the reaction [cyfluthrin results in increased expression of SQSTM1 mRNA]		 CTD PMID:31330490 PMID:36515635 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G STAT6 signal transducer and activator of transcription 6 decreases expression EXP cyfluthrin results in decreased expression of STAT6 protein CTD PMID:12755381 NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 increases expression ISO cyfluthrin results in increased expression of STING1 mRNA; cyfluthrin results in increased expression of STING1 protein CTD PMID:36515635 NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935 		JBrowse link
G SYN1 synapsin I decreases expression EXP cyfluthrin results in decreased expression of SYN1 mRNA CTD PMID:32028016 NCBI chr  X:47,571,901...47,619,857
Ensembl chr  X:47,571,901...47,619,857 		JBrowse link
G THRB thyroid hormone receptor beta multiple interactions EXP cyfluthrin binds to and results in increased activity of THRB protein CTD PMID:33049310 NCBI chr 3:24,117,153...24,495,708
Ensembl chr 3:24,117,153...24,495,756 		JBrowse link
G TJP1 tight junction protein 1 decreases expression EXP cyfluthrin results in decreased expression of TJP1 mRNA CTD PMID:36167171 NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915 		JBrowse link
G TNF tumor necrosis factor increases expression
multiple interactions		 EXP
ISO		 cyfluthrin results in increased expression of TNF mRNA
basil oil inhibits the reaction [cyfluthrin results in increased expression of TNF mRNA]; Oils, Volatile inhibits the reaction [cyfluthrin results in increased expression of TNF mRNA]
cyfluthrin results in increased expression of TNF mRNA; cyfluthrin results in increased expression of TNF protein		 CTD PMID:31330490 PMID:35126122 PMID:36515635 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TP53 tumor protein p53 increases expression EXP cyfluthrin results in increased expression of TP53 mRNA CTD PMID:31330490 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TRAPPC6A trafficking protein particle complex subunit 6A multiple interactions
decreases expression		 EXP Melatonin inhibits the reaction [cyfluthrin results in decreased expression of TRAPPC6A mRNA] CTD PMID:31330490 NCBI chr19:45,162,933...45,178,237
Ensembl chr19:45,162,928...45,178,237 		JBrowse link
G TXNRD1 thioredoxin reductase 1 decreases expression EXP cyfluthrin results in decreased expression of TXNRD1 mRNA CTD PMID:31330490 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307 		JBrowse link
G VEGFA vascular endothelial growth factor A decreases expression ISO cyfluthrin results in decreased expression of VEGFA mRNA; cyfluthrin results in decreased expression of VEGFA protein CTD PMID:36548566 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G WNT3A Wnt family member 3A increases expression EXP cyfluthrin results in increased expression of WNT3A mRNA CTD PMID:32028016 NCBI chr 1:228,006,998...228,061,271
Ensembl chr 1:228,006,998...228,061,271 		JBrowse link
G WNT5A Wnt family member 5A increases expression EXP cyfluthrin results in increased expression of WNT5A mRNA CTD PMID:32028016 NCBI chr 3:55,465,715...55,505,263
Ensembl chr 3:55,465,715...55,490,539 		JBrowse link
G WNT7A Wnt family member 7A increases expression EXP cyfluthrin results in increased expression of WNT7A mRNA CTD PMID:32028016 NCBI chr 3:13,816,258...13,880,071
Ensembl chr 3:13,816,258...13,880,071 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26040
    role 25956
      application 25177
        agrochemical 17519
          cyfluthrin 97
Path 2
Term Annotations click to browse term
  CHEBI ontology 26040
    subatomic particle 26015
      composite particle 26015
        hadron 26015
          baryon 26015
            nucleon 26015
              atomic nucleus 26015
                atom 26015
                  main group element atom 25840
                    p-block element atom 25840
                      carbon group element atom 25437
                        carbon atom 25395
                          organic molecular entity 25395
                            heteroorganic entity 24770
                              organochalcogen compound 24383
                                organooxygen compound 24060
                                  carbon oxoacid 22761
                                    carboxylic acid 22741
                                      monocarboxylic acid 21745
                                        cyclopropanecarboxylic acid 2289
                                          3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid 2146
                                            cyfluthrin 97
paths to the root