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Gene: PRDX4 (peroxiredoxin 4) Homo sapiens
Symbol: PRDX4
Name: peroxiredoxin 4
Description: Predicted to have thioredoxin peroxidase activity. Predicted to be involved in cell redox homeostasis; hydrogen peroxide catabolic process; and response to oxidative stress. Localizes to the extracellular exosome and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: antioxidant enzyme AOE372; AOE37-2; AOE372; epididymis secretory sperm binding protein Li 97n; HEL-S-97n; peroxiredoxin IV; peroxiredoxin-4; PRX-4; prx-IV; thioredoxin peroxidase (antioxidant enzyme); thioredoxin peroxidase AO372; thioredoxin-dependent peroxide reductase A0372
Mus musculus (house mouse) : Prdx4 (peroxiredoxin 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Prdx4 (peroxiredoxin 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prdx4 (peroxiredoxin 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PRDX4 (peroxiredoxin 4)
Canis lupus familiaris (dog) : PRDX4 (peroxiredoxin 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prdx4 (peroxiredoxin 4)
Sus scrofa (pig) : PRDX4 (peroxiredoxin 4)
Chlorocebus sabaeus (African green monkey) : PRDX4 (peroxiredoxin 4)
Heterocephalus glaber (naked mole-rat) : Prdx4 (peroxiredoxin 4)
more info ...
Related Pseudogenes: PRDX4P1   PRDX4P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX23,664,262 - 23,686,397 (+)Ensembl
GRCh38X23,667,493 - 23,686,397 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X23,682,377 - 23,704,516 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X23,595,566 - 23,614,435 (+)NCBINCBI36hg18NCBI36
Build 34X23,445,301 - 23,464,171NCBI
CeleraX27,807,255 - 27,826,109 (+)NCBI
Cytogenetic MapXp22.11NCBI
HuRefX21,425,714 - 21,444,033 (+)NCBIHuRef
CHM1_1X23,716,633 - 23,735,478 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on PRDX4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731497
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.