Advanced Search (OLGA)

Gene: GLA (galactosidase alpha) Homo sapiens

Analyze

Symbol:

GLA

Name:

galactosidase alpha

RGD ID:

1344140

HGNC Page

HGNC:4296

Description:

Enables alpha-galactosidase activity; protein homodimerization activity; and signaling receptor binding activity. Involved in glycosphingolipid catabolic process and oligosaccharide metabolic process. Located in Golgi apparatus; extracellular region; and lysosome. Implicated in Fabry disease.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

agalsidase alfa; alpha-D-galactosidase A; alpha-D-galactoside galactohydrolase 1; alpha-gal A; alpha-galactosidase A; GALA; galactosidase, alpha; galactosylgalactosylglucosylceramidase GLA; melibiase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Gla (galactosidase, alpha)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):	Gla (galactosidase, alpha)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Chinchilla lanigera (long-tailed chinchilla):	Gla (galactosidase alpha)	NCBI	Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):	GLA (galactosidase alpha)	NCBI	Ortholog
Canis lupus familiaris (dog):	GLA (galactosidase alpha)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gla (galactosidase alpha)	NCBI	Ortholog
Sus scrofa (pig):	GLA (galactosidase alpha)	HGNC	Ensembl, NCBI, OrthoDB
Chlorocebus sabaeus (green monkey):	GLA (galactosidase alpha)	NCBI	Ortholog
Heterocephalus glaber (naked mole-rat):	Gla (galactosidase alpha)	NCBI	Ortholog
Alliance orthologs ³
Mus musculus (house mouse):	Gla (galactosidase, alpha)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Rattus norvegicus (Norway rat):	Gla (galactosidase, alpha)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gla (galactosidase, alpha)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Caenorhabditis elegans (roundworm):	gana-1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG7997	Alliance	DIOPT (Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	gla	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus laevis (African clawed frog):	gla.S	Alliance	DIOPT (Xenbase)

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	101,397,803 - 101,407,925 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	101,393,273 - 101,408,012 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	100,652,791 - 100,662,913 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	100,539,435 - 100,549,657 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	100,458,941 - 100,469,096	NCBI
Celera	X	101,172,239 - 101,182,459 (-)	NCBI		Celera
Cytogenetic Map	X	q22.1	NCBI
HuRef	X	90,459,075 - 90,468,889 (-)	NCBI		HuRef
CHM1_1	X	100,546,260 - 100,556,479 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	99,841,918 - 99,852,040 (-)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

Imported Human Phenotype Annotations - HPO

Imported Human Phenotype Annotations - ClinVar

Send us a Message