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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:cyclophosphamide
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Accession:CHEBI:4027 term browser browse the term
Definition:A phosphorodiamide that is 1,3,2-oxazaphosphinan-2-amine 2-oxide substituted by two 2-chloroethyl groups at the amino nitrogen atom.
Synonyms:exact_synonym: N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
 related_synonym: (RS)-Cyclophosphamide;   2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide;   Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester;   Cyclophosphamide anhydrous;   Formula=C7H15Cl2N2O2P;   InChI=1S/C7H15Cl2N2O2P/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14/h1-7H2,(H,10,12);   InChIKey=CMSMOCZEIVJLDB-UHFFFAOYSA-N;   N,N-bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide;   SMILES=ClCCN(CCCl)P1(=O)NCCCO1
 xref: Beilstein:11744;   CAS:50-18-0;   DrugBank:DB00531;   Drug_Central:758;   HMDB:HMDB0014672;   KEGG:C07888;   KEGG:D07760;   LINCS:LSM-4961
 xref_mesh: MESH:D003520
 xref: PMID:15711186;   PMID:7850793;   Reaxys:11744;   Wikipedia:Cyclophosphamide


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cyclophosphamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A multiple interactions
increases expression
decreases expression		 ISO [Cyclophosphamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; ABCB1 protein affects the susceptibility to [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil]; ABCB1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]; NR1I2 protein promotes the reaction [Cyclophosphamide results in increased expression of ABCB1 protein]
Cyclophosphamide results in decreased expression of ABCB1 mRNA; Cyclophosphamide results in decreased expression of ABCB1A mRNA		 CTD PMID:12576456 PMID:20041327 PMID:20623750 PMID:30563925 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 multiple interactions
decreases response to substance		 ISO ABCC1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]
ABCC1 protein results in decreased susceptibility to Cyclophosphamide		 CTD PMID:11778547 PMID:12576456 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) multiple interactions ISO ABCG2 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide] CTD PMID:12576456 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661 		JBrowse link
G Abhd3 abhydrolase domain containing 3 increases expression ISO Cyclophosphamide results in increased expression of ABHD3 mRNA CTD PMID:21527772 NCBI chr18:10,644,411...10,706,784
Ensembl chr18:10,642,092...10,706,771 		JBrowse link
G Abi2 abl interactor 2 decreases expression ISO Cyclophosphamide results in decreased expression of ABI2 mRNA CTD PMID:27466211 NCBI chr 1:60,444,927...60,521,104
Ensembl chr 1:60,448,778...60,520,317 		JBrowse link
G Ace angiotensin I converting enzyme decreases expression ISO Cyclophosphamide results in decreased expression of ACE mRNA CTD PMID:27281708 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression ISO Cyclophosphamide results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416 		JBrowse link
G Ache acetylcholinesterase multiple interactions
increases expression		 ISO Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of ACHE protein] CTD PMID:37419146 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728 		JBrowse link
G Ackr3 atypical chemokine receptor 3 increases expression ISO Cyclophosphamide results in increased expression of ACKR3 mRNA CTD PMID:20032115 NCBI chr 1:90,131,702...90,143,446
Ensembl chr 1:90,131,702...90,144,473 		JBrowse link
G Acod1 aconitate decarboxylase 1 increases expression EXP Cyclophosphamide results in increased expression of ACOD1 mRNA CTD PMID:15331540 NCBI chr14:103,284,448...103,294,009
Ensembl chr14:103,284,413...103,294,009 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 multiple interactions
increases expression		 EXP Dexrazoxane inhibits the reaction [Cyclophosphamide results in increased expression of ACSL4 protein] CTD PMID:37690746 NCBI chr  X:141,100,989...141,173,792
Ensembl chr  X:141,100,989...141,173,531 		JBrowse link
G Actb actin, beta decreases expression
affects expression		 ISO Cyclophosphamide results in decreased expression of ACTB mRNA
Cyclophosphamide affects the expression of ACTB mRNA		 CTD PMID:10859244 PMID:12167460 NCBI chr 5:142,888,870...142,892,509
Ensembl chr 5:142,888,870...142,892,509 		JBrowse link
G Adam24 ADAM metallopeptidase domain 24 decreases expression ISO Cyclophosphamide results in decreased expression of ADAM24 mRNA CTD PMID:27281708 NCBI chr 8:41,128,118...41,135,238
Ensembl chr 8:41,128,118...41,135,238 		JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif 9 increases expression ISO Cyclophosphamide results in increased expression of ADAMTS9 mRNA CTD PMID:27281708 NCBI chr 6:92,749,680...92,921,431
Ensembl chr 6:92,749,680...92,920,473 		JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 affects expression
increases expression		 ISO Cyclophosphamide affects the expression of ADCYAP1 mRNA
Cyclophosphamide results in increased expression of ADCYAP1 protein		 CTD PMID:9776515 PMID:10754506 PMID:18563302 NCBI chr17:93,506,448...93,513,967
Ensembl chr17:93,506,445...93,513,965 		JBrowse link
G Adcyap1r1 adenylate cyclase activating polypeptide 1 receptor 1 affects expression ISO Cyclophosphamide affects the expression of ADCYAP1R1 mRNA CTD PMID:18563302 NCBI chr 6:55,428,486...55,478,440
Ensembl chr 6:55,428,963...55,478,436 		JBrowse link
G Adm adrenomedullin affects response to substance ISO ADM protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027 		JBrowse link
G Afp alpha fetoprotein affects expression EXP Cyclophosphamide affects the expression of AFP protein CTD PMID:6177358 NCBI chr 5:90,638,573...90,656,766
Ensembl chr 5:90,638,596...90,656,766 		JBrowse link
G Agl amylo-1,6-glucosidase, 4-alpha-glucanotransferase affects response to substance ISO AGL protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 3:116,533,648...116,601,815
Ensembl chr 3:116,533,648...116,601,815 		JBrowse link
G Akap8 A kinase anchor protein 8 increases expression ISO Cyclophosphamide results in increased expression of AKAP8 mRNA CTD PMID:27281708 NCBI chr17:32,522,646...32,540,212
Ensembl chr17:32,522,646...32,540,212 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions
decreases expression		 ISO Cyclophosphamide results in increased phosphorylation of and results in increased activity of AKT1 protein; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of AKT1 protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of AKT1 protein] CTD PMID:19996110 PMID:25446862 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Alad aminolevulinate, delta-, dehydratase multiple interactions ISO [Cyclophosphamide co-treated with Carmustine co-treated with Etoposide] results in decreased activity of ALAD protein CTD PMID:19162187 NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155 		JBrowse link
G Alcam activated leukocyte cell adhesion molecule increases expression EXP Cyclophosphamide results in increased expression of ALCAM mRNA CTD PMID:21041162 NCBI chr16:52,069,359...52,273,444
Ensembl chr16:52,069,359...52,274,437 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 affects response to substance
decreases response to substance
increases expression		 ISO ALDH1A1 protein affects the susceptibility to Cyclophosphamide
ALDH1A1 protein results in decreased susceptibility to Cyclophosphamide
Cyclophosphamide results in increased expression of ALDH1A1 mRNA		 CTD PMID:12513786 PMID:17403535 PMID:18854779 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial increases expression ISO Cyclophosphamide results in increased expression of ALDH2 mRNA CTD PMID:17403535 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase family 3, subfamily A1 affects response to substance ISO ALDH3A1 protein affects the susceptibility to Cyclophosphamide CTD PMID:18854779 NCBI chr11:61,099,336...61,109,244
Ensembl chr11:61,098,363...61,109,247 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein decreases expression ISO Cyclophosphamide results in decreased expression of ALOX5AP mRNA CTD PMID:17403535 NCBI chr 5:149,201,814...149,224,963
Ensembl chr 5:149,201,577...149,224,963 		JBrowse link
G Alyref Aly/REF export factor decreases expression EXP Cyclophosphamide results in decreased expression of ALYREF mRNA CTD PMID:21041162 NCBI chr11:120,485,330...120,489,342
Ensembl chr11:120,482,947...120,489,191 		JBrowse link
G Amfr autocrine motility factor receptor multiple interactions ISO AMFR mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 8:94,698,216...94,739,301
Ensembl chr 8:94,698,216...94,739,470 		JBrowse link
G Amh anti-Mullerian hormone multiple interactions
decreases expression		 ISO Cilostazol inhibits the reaction [Cyclophosphamide results in decreased expression of AMH protein] CTD PMID:32456565 NCBI chr10:80,641,074...80,643,513
Ensembl chr10:80,641,077...80,643,482 		JBrowse link
G Angpt1 angiopoietin 1 increases expression ISO Cyclophosphamide results in increased expression of ANGPT1 mRNA CTD PMID:17403535 NCBI chr15:42,288,063...42,540,373
Ensembl chr15:42,288,119...42,540,373 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression ISO Cyclophosphamide results in decreased expression of APAF1 mRNA CTD PMID:29445054 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632 		JBrowse link
G Apex1 apurinic/apyrimidinic endonuclease 1 increases expression ISO Cyclophosphamide results in increased expression of APEX1 mRNA CTD PMID:11599041 NCBI chr14:51,162,406...51,164,645
Ensembl chr14:51,162,425...51,164,596 		JBrowse link
G Apob apolipoprotein B decreases expression ISO Cyclophosphamide results in decreased expression of APOB mRNA CTD PMID:18246545 NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835 		JBrowse link
G Apoe apolipoprotein E decreases expression
increases expression		 EXP Cyclophosphamide results in decreased expression of APOE mRNA
Cyclophosphamide results in increased expression of APOE mRNA		 CTD PMID:15331540 PMID:21041162 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Arg1 arginase, liver increases expression
affects expression
decreases expression		 EXP
ISO		 Cyclophosphamide results in increased expression of ARG1 mRNA
Cyclophosphamide affects the expression of ARG1 mRNA
Cyclophosphamide results in decreased expression of ARG1 mRNA		 CTD PMID:18246545 PMID:21068404 NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382 		JBrowse link
G Arhgdib Rho, GDP dissociation inhibitor beta increases expression ISO Cyclophosphamide results in increased expression of ARHGDIB mRNA CTD PMID:21527772 NCBI chr 6:136,900,653...136,918,895
Ensembl chr 6:136,900,653...136,918,897 		JBrowse link
G Arhgef26 Rho guanine nucleotide exchange factor 26 increases expression ISO Cyclophosphamide results in increased expression of ARHGEF26 mRNA CTD PMID:20849824 NCBI chr 3:62,244,946...62,369,642
Ensembl chr 3:62,245,765...62,369,642 		JBrowse link
G Asns asparagine synthetase decreases expression ISO Cyclophosphamide metabolite results in decreased expression of ASNS mRNA CTD PMID:24356939 NCBI chr 6:7,675,169...7,693,209
Ensembl chr 6:7,675,169...7,693,254 		JBrowse link
G Atf2 activating transcription factor 2 increases expression ISO Cyclophosphamide results in increased expression of ATF2 mRNA CTD PMID:11599041 NCBI chr 2:73,646,853...73,723,094
Ensembl chr 2:73,646,853...73,722,983 		JBrowse link
G Atf5 activating transcription factor 5 decreases expression ISO Cyclophosphamide results in decreased expression of ATF5 mRNA CTD PMID:17403535 NCBI chr 7:44,461,680...44,466,082
Ensembl chr 7:44,461,680...44,466,082 		JBrowse link
G Atg3 autophagy related 3 decreases expression ISO Cyclophosphamide results in decreased expression of ATG3 mRNA CTD PMID:20849824 NCBI chr16:44,979,192...45,008,901
Ensembl chr16:44,979,148...45,008,901 		JBrowse link
G Atg5 autophagy related 5 multiple interactions
decreases expression		 EXP Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of ATG5 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of ATG5 protein] CTD PMID:32151603 NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287 		JBrowse link
G Atg7 autophagy related 7 multiple interactions
decreases expression		 EXP Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of ATG7 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of ATG7 protein] CTD PMID:32151603 NCBI chr 6:114,620,075...114,837,565
Ensembl chr 6:114,620,058...114,837,575 		JBrowse link
G Aurkb aurora kinase B increases expression ISO Cyclophosphamide results in increased expression of AURKB mRNA CTD PMID:11599041 NCBI chr11:68,936,477...68,942,490
Ensembl chr11:68,936,473...68,942,490 		JBrowse link
G Axl AXL receptor tyrosine kinase increases expression ISO Cyclophosphamide results in increased expression of AXL mRNA CTD PMID:21527772 NCBI chr 7:25,455,925...25,488,502
Ensembl chr 7:25,456,698...25,488,130 		JBrowse link
G B3galnt2 UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2 increases expression ISO Cyclophosphamide results in increased expression of B3GALNT2 mRNA CTD PMID:21527772 NCBI chr13:14,129,059...14,173,688
Ensembl chr13:14,129,054...14,173,688 		JBrowse link
G Bad BCL2-associated agonist of cell death increases expression
multiple interactions		 ISO
EXP		 Cyclophosphamide results in increased expression of BAD mRNA
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of BAD protein]		 CTD PMID:11599041 PMID:29753871 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Bag1 BCL2-associated athanogene 1 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of BAG1 mRNA CTD PMID:16322899 NCBI chr 4:40,936,398...40,948,294
Ensembl chr 4:40,936,398...40,948,294 		JBrowse link
G Bax BCL2-associated X protein increases expression
multiple interactions		 ISO
EXP		 Cyclophosphamide results in increased expression of BAX mRNA; Cyclophosphamide results in increased expression of BAX protein
Plant Extracts inhibits the reaction [Cyclophosphamide results in increased expression of BAX mRNA]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased expression of BAX protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of BAX protein]
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of BAX protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of BAX protein]		 CTD PMID:25446862 PMID:29753871 PMID:30506662 PMID:32197949 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bbc3 BCL2 binding component 3 multiple interactions
increases expression		 ISO sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased expression of BBC3 mRNA]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of BBC3 mRNA] CTD PMID:32197949 NCBI chr 7:16,042,307...16,052,130
Ensembl chr 7:16,042,318...16,052,130 		JBrowse link
G Bbs4 Bardet-Biedl syndrome 4 multiple interactions ISO BBS4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 9:59,229,249...59,260,791
Ensembl chr 9:59,229,273...59,260,791 		JBrowse link
G Bche butyrylcholinesterase multiple interactions
decreases activity		 ISO [Melphalan co-treated with Thiotepa co-treated with Cyclophosphamide] results in decreased expression of BCHE protein
Cyclophosphamide results in decreased activity of BCHE protein		 CTD PMID:4672170 PMID:4959505 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions
increases expression
decreases expression		 ISO
EXP		 [Cladribine co-treated with Cyclophosphamide co-treated with Mitoxantrone] results in decreased expression of BCL2 protein; [Cladribine co-treated with Cyclophosphamide] results in decreased expression of BCL2 protein; [Doxorubicin co-treated with Cyclophosphamide] affects the expression of BCL2 mRNA; [Doxorubicin co-treated with Dexamethasone co-treated with Vincristine co-treated with Cytarabine co-treated with Mercaptopurine co-treated with Methotrexate co-treated with Cyclophosphamide co-treated with Enzymes and Coenzymes] results in increased expression of BCL2 protein; BCL2 protein inhibits the reaction [Cyclophosphamide results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Cyclophosphamide results in increased activity of CASP9 protein]
Cyclophosphamide results in increased expression of BCL2 mRNA
Cyclophosphamide results in decreased expression of BCL2 mRNA; Cyclophosphamide results in decreased expression of BCL2 protein
Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 mRNA]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]		 CTD PMID:11723234 PMID:14503796 PMID:15582267 PMID:16322899 PMID:21182165 More... NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bcl2l1 BCL2-like 1 increases expression
decreases expression		 ISO
EXP		 Cyclophosphamide results in increased expression of BCL2L1 mRNA
Cyclophosphamide results in decreased expression of BCL2L1 mRNA		 CTD PMID:11599041 PMID:33737021 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648 		JBrowse link
G Bcl2l11 BCL2 like 11 multiple interactions
increases expression		 ISO sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased expression of BCL2L11 mRNA]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of BCL2L11 mRNA] CTD PMID:32197949 NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467 		JBrowse link
G Bcl2l2 BCL2-like 2 increases expression EXP Cyclophosphamide results in increased expression of BCL2L2 mRNA CTD PMID:21041162 NCBI chr14:55,120,900...55,125,691
Ensembl chr14:55,120,834...55,125,691 		JBrowse link
G Bcl6 B cell leukemia/lymphoma 6 decreases expression EXP
ISO		 Cyclophosphamide results in decreased expression of BCL6 mRNA
Cyclophosphamide metabolite results in decreased expression of BCL6 mRNA		 CTD PMID:21041162 PMID:24356939 NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602 		JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase, type 1 affects response to substance ISO BDH1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr16:31,241,115...31,277,719
Ensembl chr16:31,241,098...31,277,719 		JBrowse link
G Bdkrb1 bradykinin receptor, beta 1 increases expression ISO Cyclophosphamide results in increased expression of BDKRB1 mRNA CTD PMID:10498854 PMID:15576455 NCBI chr12:105,570,350...105,571,770
Ensembl chr12:105,569,344...105,571,687 		JBrowse link
G Bdkrb2 bradykinin receptor, beta 2 affects expression ISO Cyclophosphamide affects the expression of BDKRB2 mRNA CTD PMID:15576455 NCBI chr12:105,529,431...105,561,503
Ensembl chr12:105,529,485...105,561,496 		JBrowse link
G Bdnf brain derived neurotrophic factor increases expression
multiple interactions		 ISO Cyclophosphamide results in increased expression of BDNF mRNA; Cyclophosphamide results in increased expression of BDNF protein
O-1602 compound inhibits the reaction [Cyclophosphamide results in increased expression of BDNF protein]		 CTD PMID:10683293 PMID:32615180 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352 		JBrowse link
G Becn1 beclin 1, autophagy related multiple interactions
decreases expression		 ISO
EXP		 BECN1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]
Cyclophosphamide results in decreased expression of BECN1 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of BECN1 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of BECN1 protein]		 CTD PMID:16896004 PMID:32151603 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G Bik BCL2-interacting killer decreases expression ISO Cyclophosphamide results in decreased expression of BIK mRNA CTD PMID:17403535 NCBI chr15:83,410,992...83,428,836
Ensembl chr15:83,411,063...83,428,835 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of BIRC3 mRNA CTD PMID:24356939 NCBI chr 9:7,848,698...7,873,199
Ensembl chr 9:7,848,700...7,873,187 		JBrowse link
G Blvrb biliverdin reductase B decreases expression ISO Cyclophosphamide results in decreased expression of BLVRB protein CTD PMID:9006340 NCBI chr 7:27,147,403...27,165,406
Ensembl chr 7:27,147,403...27,165,569 		JBrowse link
G Bpi bactericidal permeablility increasing protein decreases expression ISO Cyclophosphamide results in decreased expression of BPI mRNA CTD PMID:17403535 NCBI chr 2:158,099,983...158,126,453
Ensembl chr 2:158,100,014...158,126,451 		JBrowse link
G Brpf1 bromodomain and PHD finger containing, 1 increases expression ISO Cyclophosphamide results in increased expression of BRPF1 mRNA CTD PMID:27281708 NCBI chr 6:113,283,824...113,301,823
Ensembl chr 6:113,284,098...113,301,821 		JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin increases expression EXP Cyclophosphamide results in increased expression of BSCL2 mRNA CTD PMID:22003191 NCBI chr19:8,814,831...8,826,047
Ensembl chr19:8,814,831...8,826,047 		JBrowse link
G Bsg basigin decreases expression EXP Cyclophosphamide results in decreased expression of BSG mRNA CTD PMID:15331540 NCBI chr10:79,540,192...79,547,813
Ensembl chr10:79,540,325...79,547,803 		JBrowse link
G Btg1 BTG anti-proliferation factor 1 decreases expression EXP Cyclophosphamide results in decreased expression of BTG1 mRNA CTD PMID:21041162 NCBI chr10:96,452,863...96,458,675
Ensembl chr10:96,452,868...96,458,671 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Cyclophosphamide results in increased expression of BTG2 mRNA CTD PMID:29445054 NCBI chr 1:134,002,603...134,006,893
Ensembl chr 1:134,002,908...134,006,858 		JBrowse link
G Btg3 BTG anti-proliferation factor 3 multiple interactions ISO BTG3 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr16:78,156,748...78,174,069
Ensembl chr16:78,129,525...78,174,080 		JBrowse link
G Bub3 BUB3 mitotic checkpoint protein multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of BUB3 mRNA CTD PMID:16322899 NCBI chr 7:131,162,081...131,173,625
Ensembl chr 7:131,161,951...131,173,624 		JBrowse link
G C1qa complement component 1, q subcomponent, alpha polypeptide increases expression EXP Cyclophosphamide results in increased expression of C1QA mRNA CTD PMID:21041162 NCBI chr 4:136,623,227...136,626,155
Ensembl chr 4:136,623,228...136,626,114 		JBrowse link
G C3 complement component 3 increases expression EXP Cyclophosphamide results in increased expression of C3 mRNA CTD PMID:21041162 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G Cabp1 calcium binding protein 1 decreases expression ISO Cyclophosphamide results in decreased expression of CABP1 mRNA CTD PMID:11906922 NCBI chr 5:115,306,750...115,332,440
Ensembl chr 5:115,306,748...115,332,440 		JBrowse link
G Cabp2 calcium binding protein 2 decreases expression ISO Cyclophosphamide results in decreased expression of CABP2 mRNA CTD PMID:11906922 NCBI chr19:4,131,469...4,137,340
Ensembl chr19:4,131,578...4,137,340 		JBrowse link
G Cacna1h calcium channel, voltage-dependent, T type, alpha 1H subunit increases expression
multiple interactions		 EXP Cyclophosphamide results in increased expression of CACNA1H protein
3-cyanoalanine inhibits the reaction [[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of CACNA1H protein]; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of CACNA1H protein		 CTD PMID:29129814 NCBI chr17:25,593,259...25,655,308
Ensembl chr17:25,593,259...25,652,759 		JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha increases expression
multiple interactions		 ISO Cyclophosphamide results in increased expression of CALCA protein
O-1602 compound inhibits the reaction [Cyclophosphamide results in increased expression of CALCA protein]		 CTD PMID:32615180 NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592 		JBrowse link
G Calr calreticulin increases expression
decreases expression		 ISO Cyclophosphamide results in increased expression of CALR mRNA
Cyclophosphamide results in decreased expression of CALR mRNA		 CTD PMID:11599041 PMID:11906922 PMID:18246545 NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563 		JBrowse link
G Canx calnexin decreases expression ISO Cyclophosphamide results in decreased expression of CANX mRNA CTD PMID:11906922 NCBI chr11:50,184,784...50,216,500
Ensembl chr11:50,184,788...50,216,500 		JBrowse link
G Capn2 calpain 2 increases expression EXP Cyclophosphamide results in increased expression of CAPN2 mRNA CTD PMID:21041162 NCBI chr 1:182,294,818...182,345,175
Ensembl chr 1:182,294,825...182,345,173 		JBrowse link
G Car12 carbonic anhydrase 12 multiple interactions ISO CA12 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 9:66,619,026...66,674,127
Ensembl chr 9:66,620,968...66,674,127 		JBrowse link
G Car2 carbonic anhydrase 2 decreases expression
increases expression		 ISO
EXP		 Cyclophosphamide results in decreased expression of CA2 mRNA
Cyclophosphamide results in increased expression of CAR2 mRNA		 CTD PMID:15331540 PMID:17403535 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830 		JBrowse link
G Car7 carbonic anhydrase 7 decreases expression ISO Cyclophosphamide results in decreased expression of CAR7 mRNA CTD PMID:27281708 NCBI chr 8:105,261,326...105,276,979
Ensembl chr 8:105,261,321...105,276,975 		JBrowse link
G Cars1 cysteinyl-tRNA synthetase 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of CARS1 mRNA CTD PMID:24356939 NCBI chr 7:143,110,967...143,153,827
Ensembl chr 7:143,110,967...143,153,827 		JBrowse link
G Casp1 caspase 1 decreases expression
increases expression
multiple interactions		 ISO
EXP		 Cyclophosphamide results in decreased expression of CASP1 mRNA
Cyclophosphamide results in increased expression of CASP1 mRNA
Cyclophosphamide results in increased expression of CASP1 protein
Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of CASP1 protein]]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of CASP1 protein]		 CTD PMID:17403535 PMID:21041162 PMID:35762198 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290 		JBrowse link
G Casp3 caspase 3 multiple interactions
decreases response to substance
increases expression
increases activity
increases cleavage		 ISO
EXP		 [Bortezomib co-treated with oblimersen co-treated with Cyclophosphamide] results in increased activity of CASP3 protein; BCL2 protein inhibits the reaction [Cyclophosphamide results in increased activity of CASP3 protein]; Cyclophosphamide results in increased cleavage of and results in increased activity of CASP3 protein
CASP3 protein alternative form results in decreased susceptibility to Cyclophosphamide
Cyclophosphamide results in increased expression of CASP3 mRNA
ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of CASP3 protein]
Cilostazol inhibits the reaction [Cyclophosphamide results in increased expression of CASP3 protein]; Cyclophosphamide results in increased expression of and results in increased activity of CASP3 protein; Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP3 protein]]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of and results in increased activity of CASP3 protein]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased activity of CASP3 protein]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP3 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased activity of CASP3 protein]		 CTD PMID:11723234 PMID:14503796 PMID:16675587 PMID:17020986 PMID:17898787 More... NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp4 caspase 4, apoptosis-related cysteine peptidase increases cleavage
multiple interactions		 ISO Cyclophosphamide results in increased cleavage of CASP4 protein
sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP4 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP4 protein]		 CTD PMID:32197949 NCBI chr 9:5,308,816...5,336,791
Ensembl chr 9:5,308,828...5,336,783 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases response to substance		 ISO [Methotrexate results in increased expression of CASP8 protein] which results in increased susceptibility to Cyclophosphamide metabolite; Cyclophosphamide metabolite results in increased expression of and results in increased cleavage of CASP8 protein; Cyclophosphamide results in increased cleavage of and results in increased activity of CASP8 protein
CASP8 protein results in increased susceptibility to Cyclophosphamide metabolite		 CTD PMID:17898787 PMID:22010212 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
increases expression		 ISO
EXP		 BCL2 protein inhibits the reaction [Cyclophosphamide results in increased activity of CASP9 protein]; Cyclophosphamide results in increased cleavage of and results in increased activity of CASP9 protein
Cyclophosphamide results in increased expression of CASP9 protein
ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of CASP9 protein]		 CTD PMID:11723234 PMID:17898787 PMID:30506662 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Cat catalase decreases expression
multiple interactions
affects activity
decreases activity		 ISO
EXP		 Cyclophosphamide results in decreased expression of CAT protein
mangiferin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; naringin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; Pentoxifylline inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; pimagedine inhibits the reaction [Cyclophosphamide results in decreased expression of CAT protein]; Quercetin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; Rutin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; thymoquinone inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]
Buthionine Sulfoximine promotes the reaction [Cyclophosphamide results in decreased activity of CAT protein]; cinnamic acid inhibits the reaction [Cyclophosphamide affects the activity of CAT protein]; Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of CAT protein]; Eicosapentaenoic Acid inhibits the reaction [Cyclophosphamide affects the activity of CAT protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; NFE2L2 gene mutant form promotes the reaction [Cyclophosphamide results in decreased expression of CAT protein]; Plant Extracts inhibits the reaction [Buthionine Sulfoximine promotes the reaction [Cyclophosphamide results in decreased activity of CAT protein]]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of CAT mRNA]
Cyclophosphamide results in decreased expression of CAT mRNA; Cyclophosphamide results in decreased expression of CAT protein		 CTD PMID:16076520 PMID:19107871 PMID:20052769 PMID:20957680 PMID:21772021 More... NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Ccin calicin increases expression ISO Cyclophosphamide results in increased expression of CCIN protein CTD PMID:17475930 NCBI chr 4:43,983,504...43,985,533
Ensembl chr 4:43,983,483...43,985,423 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
decreases expression
multiple interactions		 EXP
ISO		 Cyclophosphamide results in increased expression of CCL2 mRNA
Cyclophosphamide results in decreased expression of CCL2 protein
naringin inhibits the reaction [Cyclophosphamide results in increased expression of CCL2 mRNA]
Cyclophosphamide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL2 protein]		 CTD PMID:18848347 PMID:21068404 PMID:33992719 PMID:36416909 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccl25 C-C motif chemokine ligand 25 decreases expression EXP Cyclophosphamide results in decreased expression of CCL25 mRNA CTD PMID:21041162 NCBI chr 8:4,375,207...4,410,020
Ensembl chr 8:4,375,210...4,410,020 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression
multiple interactions		 EXP
ISO		 Cyclophosphamide results in decreased expression of CCL3 protein
Cyclophosphamide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL3 protein]		 CTD PMID:21880982 PMID:36416909 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression EXP Cyclophosphamide results in increased expression of CCL7 mRNA CTD PMID:15331540 PMID:21041162 NCBI chr11:81,936,538...81,938,351
Ensembl chr11:81,936,538...81,938,351 		JBrowse link
G Ccl8 C-C motif chemokine ligand 8 increases expression EXP Cyclophosphamide results in increased expression of CCL8 mRNA CTD PMID:21041162 NCBI chr11:82,006,011...82,007,625
Ensembl chr11:82,006,011...82,007,625 		JBrowse link
G Ccl9 C-C motif chemokine ligand 9 increases expression EXP Cyclophosphamide results in increased expression of CCL9 mRNA CTD PMID:21041162 NCBI chr11:83,463,743...83,469,462
Ensembl chr11:83,463,745...83,469,462 		JBrowse link
G Ccna2 cyclin A2 decreases expression EXP Cyclophosphamide results in decreased expression of CCNA2 mRNA CTD PMID:21041162 NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299 		JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP Cyclophosphamide results in decreased expression of CCND1 protein CTD PMID:33737021 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Ccnd2 cyclin D2 increases expression EXP Cyclophosphamide results in increased expression of CCND2 mRNA CTD PMID:21041162 NCBI chr 6:127,102,125...127,131,913
Ensembl chr 6:127,102,125...127,129,156 		JBrowse link
G Ccnd3 cyclin D3 decreases expression EXP Cyclophosphamide results in decreased expression of CCND3 mRNA CTD PMID:21041162 NCBI chr17:47,815,976...47,910,614
Ensembl chr17:47,815,976...47,910,616 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 increases expression EXP Cyclophosphamide results in increased expression of CCR5 mRNA CTD PMID:15331540 NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736 		JBrowse link
G Ccr8 C-C motif chemokine receptor 8 decreases expression ISO Cyclophosphamide results in decreased expression of CCR8 mRNA CTD PMID:17403535 NCBI chr 9:119,921,199...119,923,972
Ensembl chr 9:119,921,180...119,923,972 		JBrowse link
G Ccr9 C-C motif chemokine receptor 9 decreases expression EXP Cyclophosphamide results in decreased expression of CCR9 mRNA CTD PMID:21041162 NCBI chr 9:123,596,276...123,612,522
Ensembl chr 9:123,507,504...123,613,395 		JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 decreases expression ISO Cyclophosphamide results in decreased expression of CCT3 mRNA CTD PMID:11906922 NCBI chr 3:88,204,442...88,229,073
Ensembl chr 3:88,204,423...88,229,074 		JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 decreases expression ISO Cyclophosphamide results in decreased expression of CCT5 mRNA CTD PMID:11906922 NCBI chr15:31,590,946...31,601,992
Ensembl chr15:31,590,946...31,601,950 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 decreases expression ISO Cyclophosphamide results in decreased expression of CCT7 mRNA CTD PMID:11906922 NCBI chr 6:85,428,487...85,445,459
Ensembl chr 6:85,428,496...85,445,457 		JBrowse link
G Cd14 CD14 antigen increases expression EXP Cyclophosphamide results in increased expression of CD14 mRNA CTD PMID:15331540 PMID:21041162 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851 		JBrowse link
G Cd151 CD151 antigen increases expression EXP Cyclophosphamide results in increased expression of CD151 mRNA CTD PMID:21041162 NCBI chr 7:141,047,275...141,051,394
Ensembl chr 7:141,047,305...141,051,386 		JBrowse link
G Cd2 CD2 antigen decreases expression EXP Cyclophosphamide results in decreased expression of CD2 mRNA CTD PMID:21041162 NCBI chr 3:101,183,224...101,195,255
Ensembl chr 3:101,183,215...101,195,255 		JBrowse link
G Cd27 CD27 antigen decreases expression EXP Cyclophosphamide results in decreased expression of CD27 mRNA CTD PMID:21041162 NCBI chr 6:125,209,583...125,214,014
Ensembl chr 6:125,209,585...125,213,973 		JBrowse link
G Cd28 CD28 antigen decreases expression EXP Cyclophosphamide results in decreased expression of CD28 mRNA CTD PMID:21041162 NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518 		JBrowse link
G Cd38 CD38 antigen increases expression EXP Cyclophosphamide results in increased expression of CD38 mRNA CTD PMID:21041162 NCBI chr 5:44,026,153...44,069,714
Ensembl chr 5:44,025,895...44,069,717 		JBrowse link
G Cd3d CD3 antigen, delta polypeptide decreases expression EXP Cyclophosphamide results in decreased expression of CD3D mRNA CTD PMID:21041162 NCBI chr 9:44,893,067...44,898,350
Ensembl chr 9:44,893,084...44,898,637 		JBrowse link
G Cd3e CD3 antigen, epsilon polypeptide decreases expression EXP Cyclophosphamide results in decreased expression of CD3E mRNA CTD PMID:21041162 NCBI chr 9:44,910,033...44,920,961
Ensembl chr 9:44,910,038...44,920,925 		JBrowse link
G Cd3g CD3 antigen, gamma polypeptide decreases expression EXP Cyclophosphamide results in decreased expression of CD3G mRNA CTD PMID:21041162 NCBI chr 9:44,880,870...44,891,729
Ensembl chr 9:44,880,870...44,891,729 		JBrowse link
G Cd4 CD4 antigen decreases expression EXP Cyclophosphamide results in decreased expression of CD4 mRNA CTD PMID:21041162 NCBI chr 6:124,841,656...124,865,210
Ensembl chr 6:124,841,655...124,865,184 		JBrowse link
G Cd40 CD40 antigen decreases expression EXP Cyclophosphamide results in decreased expression of CD40 mRNA CTD PMID:21041162 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Cd5 CD5 antigen decreases expression EXP Cyclophosphamide results in decreased expression of CD5 mRNA CTD PMID:21041162 NCBI chr19:10,695,471...10,716,390
Ensembl chr19:10,694,480...10,716,366 		JBrowse link
G Cd6 CD6 antigen decreases expression EXP Cyclophosphamide results in decreased expression of CD6 mRNA CTD PMID:21041162 NCBI chr19:10,766,703...10,807,427
Ensembl chr19:10,766,705...10,807,422 		JBrowse link
G Cd69 CD69 antigen decreases expression EXP
ISO		 Cyclophosphamide results in decreased expression of CD69 mRNA
Cyclophosphamide metabolite results in decreased expression of CD69 mRNA		 CTD PMID:21041162 PMID:24356939 NCBI chr 6:129,244,287...129,252,332
Ensembl chr 6:129,244,288...129,252,399 		JBrowse link
G Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) decreases expression EXP Cyclophosphamide results in decreased expression of CD74 mRNA CTD PMID:15331540 NCBI chr18:60,936,921...60,945,724
Ensembl chr18:60,936,920...60,945,724 		JBrowse link
G Cd79b CD79B antigen decreases expression EXP Cyclophosphamide results in decreased expression of CD79B mRNA CTD PMID:15331540 NCBI chr11:106,202,167...106,205,388
Ensembl chr11:106,202,167...106,205,588 		JBrowse link
G Cd83 CD83 antigen decreases expression EXP Cyclophosphamide results in decreased expression of CD83 mRNA CTD PMID:15331540 NCBI chr13:43,938,661...43,956,608
Ensembl chr13:43,938,251...43,956,608 		JBrowse link
G Cd84 CD84 antigen increases expression ISO Cyclophosphamide metabolite results in increased expression of CD84 mRNA CTD PMID:24356939 NCBI chr 1:171,667,261...171,718,288
Ensembl chr 1:171,667,265...171,718,285 		JBrowse link
G Cd8a CD8 subunit alpha decreases expression EXP Cyclophosphamide results in decreased expression of CD8A mRNA CTD PMID:21041162 NCBI chr 6:71,350,411...71,356,155
Ensembl chr 6:71,350,411...71,356,157 		JBrowse link
G Cd8b1 CD8 subunit beta 1 decreases expression EXP Cyclophosphamide results in decreased expression of CD8B1 mRNA CTD PMID:21041162 NCBI chr 6:71,299,772...71,314,476
Ensembl chr 6:71,299,772...71,314,478 		JBrowse link
G Cdc20 cell division cycle 20 increases expression ISO Cyclophosphamide results in increased expression of CDC20 mRNA CTD PMID:11599041 NCBI chr 4:118,290,098...118,294,540
Ensembl chr 4:118,290,098...118,294,549 		JBrowse link
G Cdh1 cadherin 1 affects expression ISO Cyclophosphamide affects the expression of CDH1 mRNA CTD PMID:10859244 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878 		JBrowse link
G Cdh2 cadherin 2 affects expression ISO Cyclophosphamide affects the expression of CDH2 mRNA CTD PMID:10859244 NCBI chr18:16,721,934...16,942,303
Ensembl chr18:16,721,934...16,942,303 		JBrowse link
G Cdh3 cadherin 3 affects expression ISO Cyclophosphamide affects the expression of CDH3 mRNA CTD PMID:10859244 NCBI chr 8:107,237,484...107,283,543
Ensembl chr 8:107,237,523...107,283,929 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression EXP Cyclophosphamide results in decreased expression of CDK2 mRNA CTD PMID:21041162 NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression ISO
EXP		 Cyclophosphamide results in increased expression of CDKN1A mRNA CTD PMID:15331540 PMID:21527772 PMID:29445054 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of CDKN1B mRNA CTD PMID:16322899 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476 		JBrowse link
G Cdkn1c cyclin dependent kinase inhibitor 1C increases expression EXP Cyclophosphamide results in increased expression of CDKN1C mRNA CTD PMID:21041162 NCBI chr 7:143,012,076...143,014,735
Ensembl chr 7:143,012,076...143,014,787 		JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D decreases expression EXP Cyclophosphamide results in decreased expression of CDKN2D mRNA CTD PMID:21041162 NCBI chr 9:21,199,759...21,202,553
Ensembl chr 9:21,199,706...21,202,703 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta decreases expression ISO Cyclophosphamide metabolite results in decreased expression of CEBPB mRNA CTD PMID:24356939 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338 		JBrowse link
G Cel carboxyl ester lipase increases expression ISO Cyclophosphamide results in increased expression of CEL mRNA CTD PMID:21527772 NCBI chr 2:28,445,831...28,453,415
Ensembl chr 2:28,445,807...28,453,415 		JBrowse link
G Cfb complement factor B increases expression EXP Cyclophosphamide results in increased expression of CFB mRNA CTD PMID:21041162 NCBI chr17:35,075,350...35,081,492
Ensembl chr17:35,075,350...35,081,494 		JBrowse link
G Cfi complement component factor i affects response to substance ISO CFI protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 3:129,630,432...129,668,978
Ensembl chr 3:129,629,533...129,668,981 		JBrowse link
G Chac1 ChaC, cation transport regulator 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of CHAC1 mRNA; Cyclophosphamide results in decreased expression of CHAC1 mRNA CTD PMID:23824090 PMID:24356939 NCBI chr 2:119,181,723...119,184,807
Ensembl chr 2:119,181,710...119,184,862 		JBrowse link
G Champ1 chromosome alignment maintaining phosphoprotein 1 increases expression ISO Cyclophosphamide results in increased expression of CHAMP1 mRNA CTD PMID:27281708 NCBI chr 8:13,919,699...13,931,637
Ensembl chr 8:13,919,641...13,931,639 		JBrowse link
G Chd5 chromodomain helicase DNA binding protein 5 decreases expression ISO Cyclophosphamide results in decreased expression of CHD5 mRNA CTD PMID:27281708 NCBI chr 4:152,423,103...152,474,651
Ensembl chr 4:152,423,108...152,474,651 		JBrowse link
G Chga chromogranin A decreases expression EXP Cyclophosphamide results in decreased expression of CHGA mRNA CTD PMID:15331540 NCBI chr12:102,521,200...102,531,286
Ensembl chr12:102,521,228...102,531,287 		JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 increases expression ISO Cyclophosphamide results in increased expression of CHRM5 protein CTD PMID:16125470 NCBI chr 2:112,306,055...112,365,487
Ensembl chr 2:112,309,516...112,311,114 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 affects expression
decreases expression		 ISO Cyclophosphamide affects the expression of CITED2 mRNA
Cyclophosphamide results in decreased expression of CITED2 mRNA		 CTD PMID:18246545 NCBI chr10:17,598,452...17,601,422
Ensembl chr10:17,598,966...17,601,422 		JBrowse link
G Ckm creatine kinase, muscle multiple interactions
increases expression		 ISO Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of CKM protein]]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of CKM protein] CTD PMID:35762198 NCBI chr 7:19,145,019...19,155,508
Ensembl chr 7:19,138,701...19,156,766 		JBrowse link
G Cldn1 claudin 1 multiple interactions
decreases expression		 EXP Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of CLDN1 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of CLDN1 protein] CTD PMID:32151603 NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591 		JBrowse link
G Cldn4 claudin 4 multiple interactions
decreases expression		 ISO Anthocyanins inhibits the reaction [Cyclophosphamide results in decreased expression of CLDN4 protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of CLDN4 protein] CTD PMID:25451569 NCBI chr 5:134,973,977...134,975,788
Ensembl chr 5:134,973,973...134,975,788 		JBrowse link
G Clic4 chloride intracellular channel 4 increases expression EXP Cyclophosphamide results in increased expression of CLIC4 mRNA CTD PMID:15331540 NCBI chr 4:134,941,280...135,000,071
Ensembl chr 4:134,941,280...135,000,125 		JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 decreases expression ISO Cyclophosphamide results in decreased expression of CLIP1 mRNA CTD PMID:27281708 NCBI chr 5:123,715,857...123,822,527
Ensembl chr 5:123,715,858...123,822,681 		JBrowse link
G Coch cochlin affects response to substance ISO COCH protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr12:51,640,156...51,652,558
Ensembl chr12:51,640,124...51,652,554 		JBrowse link
G Comt catechol-O-methyltransferase increases expression EXP Cyclophosphamide results in increased expression of COMT mRNA CTD PMID:21041162 NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602 		JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 decreases expression ISO Cyclophosphamide results in decreased expression of COX7A2 mRNA CTD PMID:17403535 NCBI chr 9:79,662,523...79,667,135
Ensembl chr 9:79,662,643...79,667,160 		JBrowse link
G Crabp2 cellular retinoic acid binding protein II increases expression ISO Cyclophosphamide results in increased expression of CRABP2 mRNA CTD PMID:21527772 NCBI chr 3:87,856,000...87,860,679
Ensembl chr 3:87,855,973...87,860,683 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression EXP Cyclophosphamide results in increased expression of CREB1 protein modified form CTD PMID:18299998 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707 		JBrowse link
G Crem cAMP responsive element modulator decreases expression
multiple interactions		 ISO Cyclophosphamide results in decreased expression of CREM mRNA; Cyclophosphamide results in decreased expression of CREM protein
Drugs, Chinese Herbal inhibits the reaction [Cyclophosphamide results in decreased expression of CREM mRNA]; Drugs, Chinese Herbal inhibits the reaction [Cyclophosphamide results in decreased expression of CREM protein]		 CTD PMID:17624719 NCBI chr18:3,263,181...3,337,688
Ensembl chr18:3,266,048...3,337,748 		JBrowse link
G Crh corticotropin releasing hormone increases expression ISO
EXP		 Cyclophosphamide results in increased expression of CRH mRNA; Cyclophosphamide results in increased expression of CRH protein CTD PMID:15276878 PMID:16614059 PMID:17335920 NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 increases expression ISO Cyclophosphamide results in increased expression of CRHR2 protein CTD PMID:16614059 NCBI chr 6:55,067,033...55,110,001
Ensembl chr 6:55,067,034...55,110,001 		JBrowse link
G Crp C-reactive protein, pentraxin-related multiple interactions
increases secretion		 ISO allyl sulfide inhibits the reaction [Cyclophosphamide results in increased secretion of CRP protein] CTD PMID:31779506 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598 		JBrowse link
G Csf1 colony stimulating factor 1 (macrophage) multiple interactions EXP [Cyclophosphamide co-treated with Sizofiran] results in increased expression of CSF1 mRNA CTD PMID:10052129 NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785 		JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) affects activity
increases expression		 ISO CSF2 protein affects the activity of Cyclophosphamide
Cyclophosphamide results in increased expression of CSF2 protein		 CTD PMID:8349185 PMID:18848347 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493 		JBrowse link
G Csk c-src tyrosine kinase decreases expression EXP Cyclophosphamide results in decreased expression of CSK mRNA CTD PMID:21041162 NCBI chr 9:57,533,929...57,560,758
Ensembl chr 9:57,533,929...57,560,914 		JBrowse link
G Cst7 cystatin F (leukocystatin) decreases expression ISO Cyclophosphamide results in decreased expression of CST7 mRNA CTD PMID:17403535 NCBI chr 2:150,412,335...150,420,864
Ensembl chr 2:150,412,335...150,420,864 		JBrowse link
G Csta2 cystatin A family member 2 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of CSTA mRNA CTD PMID:24356939 NCBI chr16:36,041,932...36,077,813
Ensembl chr16:36,041,838...36,077,810 		JBrowse link
G Cth cystathionine gamma lyase increases expression EXP Cyclophosphamide results in increased expression of CTH protein CTD PMID:29129814 NCBI chr 3:157,599,885...157,630,718
Ensembl chr 3:157,599,885...157,630,714 		JBrowse link
G Ctnnbip1 catenin beta interacting protein 1 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of CTNNBIP1 mRNA CTD PMID:16322899 NCBI chr 4:149,602,698...149,650,894
Ensembl chr 4:149,602,693...149,650,894 		JBrowse link
G Ctnnd2 catenin delta 2 multiple interactions ISO CTNND2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr15:30,172,680...31,029,490
Ensembl chr15:30,172,739...31,029,487 		JBrowse link
G Ctsd cathepsin D multiple interactions
increases activity		 EXP
ISO		 [Cyclophosphamide co-treated with Mecamylamine] results in increased expression of CTSD mRNA
Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of CTSD protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased activity of CTSD protein]		 CTD PMID:18433785 PMID:25451569 NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775 		JBrowse link
G Ctsh cathepsin H increases expression ISO Cyclophosphamide results in increased expression of CTSH mRNA CTD PMID:17403535 NCBI chr 9:89,936,320...89,958,148
Ensembl chr 9:89,936,205...89,958,142 		JBrowse link
G Ctsl cathepsin L increases expression
decreases expression
multiple interactions		 ISO
EXP		 Cyclophosphamide results in increased expression of CTSL mRNA
Cyclophosphamide results in decreased expression of CTSL mRNA
5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline inhibits the reaction [Cyclophosphamide results in decreased expression of CTSL mRNA]		 CTD PMID:17403535 PMID:30760223 NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression ISO Cyclophosphamide results in increased expression of CX3CL1 protein CTD PMID:16651033 NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 increases expression ISO Cyclophosphamide results in increased expression of CX3CR1 protein CTD PMID:16651033 NCBI chr 9:119,877,749...119,897,362
Ensembl chr 9:119,877,749...119,898,945 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression ISO Cyclophosphamide results in increased expression of CXCL1 protein CTD PMID:18848347 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 affects expression
increases response to substance
increases expression		 EXP Cyclophosphamide affects the expression of CXCL10 mRNA
CXCL10 protein results in increased susceptibility to Cyclophosphamide
Cyclophosphamide results in increased expression of CXCL10 protein		 CTD PMID:18957084 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748 		JBrowse link
G Cxcl11 chemokine (C-X-C motif) ligand 11 increases expression EXP Cyclophosphamide results in increased expression of CXCL11 protein CTD PMID:18957084 NCBI chr 5:92,507,403...92,511,155
Ensembl chr 5:92,507,403...92,513,344 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 affects expression
increases expression		 EXP
ISO		 Cyclophosphamide affects the expression of CXCL12 mRNA
Cyclophosphamide results in increased expression of CXCL12 mRNA
Cyclophosphamide results in increased expression of CXCL12 mRNA; Cyclophosphamide results in increased expression of CXCL12 protein		 CTD PMID:12624490 PMID:16337237 PMID:19066630 PMID:20032115 NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328 		JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 increases expression
multiple interactions		 ISO
EXP		 Cyclophosphamide results in increased expression of CXCL8 mRNA
Cyclophosphamide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CXCL8 protein]
Cyclophosphamide results in increased expression of CXCL5 mRNA		 CTD PMID:15331540 PMID:29594315 PMID:36416909 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions EXP [Cyclophosphamide co-treated with Dexamethasone] inhibits the reaction [Paraquat results in increased expression of CXCL2 mRNA] CTD PMID:36031164 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression
multiple interactions
affects expression		 EXP Cyclophosphamide results in increased expression of CXCL1 mRNA; Cyclophosphamide results in increased expression of CXCL1 protein
VIP protein inhibits the reaction [Cyclophosphamide results in increased expression of CXCL1 protein]
Cyclophosphamide affects the expression of CXCL3 mRNA		 CTD PMID:15331540 PMID:18483878 PMID:18957084 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 affects expression
increases expression
decreases expression		 EXP Cyclophosphamide affects the expression of CXCL9 mRNA
Cyclophosphamide results in increased expression of CXCL9 mRNA; Cyclophosphamide results in increased expression of CXCL9 protein
Cyclophosphamide results in decreased expression of CXCL9 protein		 CTD PMID:15331540 PMID:18957084 PMID:21041162 PMID:21880982 NCBI chr 5:92,469,190...92,475,938
Ensembl chr 5:92,469,206...92,475,938 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions
affects localization
decreases expression
increases expression		 ISO
EXP		 Cyclophosphamide promotes the reaction [MIF protein binds to CXCR4 protein]
Cyclophosphamide affects the localization of CXCR4 protein
Cyclophosphamide results in decreased expression of CXCR4 mRNA
Cyclophosphamide results in increased expression of CXCR4 mRNA; Cyclophosphamide results in increased expression of CXCR4 protein		 CTD PMID:19066630 PMID:20032115 PMID:21041162 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030 		JBrowse link
G Cxcr6 C-X-C motif chemokine receptor 6 increases expression EXP Cyclophosphamide results in increased expression of CXCR6 mRNA CTD PMID:21041162 NCBI chr 9:123,635,542...123,640,819
Ensembl chr 9:123,635,540...123,640,825 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity EXP Cyclophosphamide results in decreased activity of CYP1A1 protein CTD PMID:18420780 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity EXP Cyclophosphamide results in decreased activity of CYP1A2 protein CTD PMID:18420780 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases expression ISO Cyclophosphamide results in decreased expression of CYP1B1 mRNA CTD PMID:12167460 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490 		JBrowse link
G Cyp2a4 cytochrome P450, family 2, subfamily a, polypeptide 4 decreases activity EXP Cyclophosphamide results in decreased activity of CYP2A4 protein CTD PMID:18420780 NCBI chr 7:26,006,617...26,014,513
Ensembl chr 7:26,006,594...26,014,513 		JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 multiple interactions
affects hydroxylation
increases hydroxylation
increases response to substance
increases expression
increases metabolic processing
increases activity		 ISO
EXP		 [Cyclophosphamide results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; [Doxorubicin co-treated with Cyclophosphamide] affects the expression of CYP2B6 mRNA; Cyclophosphamide results in decreased expression of and results in decreased activity of CYP2B6 protein; CYP2B6 protein polymorphism affects the activity of and affects the susceptibility to Cyclophosphamide; CYP2B6 protein results in increased metabolism of and results in increased susceptibility to Cyclophosphamide; POR promotes the reaction [CYP2B6 results in increased susceptibility to Cyclophosphamide]; POR protein promotes the reaction [CYP2B6 protein results in increased susceptibility to Cyclophosphamide]
CYP2B6 intron polymorphism affects the hydroxylation of Cyclophosphamide; CYP2B6 promoter polymorphism affects the hydroxylation of Cyclophosphamide
CYP2B6 protein results in increased hydroxylation of Cyclophosphamide
CYP2B6 protein results in increased susceptibility to Cyclophosphamide; CYP2B6 results in increased susceptibility to Cyclophosphamide
Cyclophosphamide results in increased expression of CYP2B10 mRNA
CYP2B6 protein results in increased metabolism of Cyclophosphamide
CYP2B6 protein results in increased activity of Cyclophosphamide		 CTD PMID:9766669 PMID:10919648 PMID:11389073 PMID:11723234 PMID:12498089 More... NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049 		JBrowse link
G Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13 increases expression ISO Cyclophosphamide results in increased expression of CYP2B2 mRNA; Cyclophosphamide results in increased expression of CYP2B2 protein CTD PMID:16019949 PMID:17634551 NCBI chr 7:25,760,813...25,795,622
Ensembl chr 7:25,760,922...25,795,622 		JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 increases expression
increases activity
increases metabolic processing		 EXP
ISO		 Cyclophosphamide results in increased expression of CYP2C29 mRNA
CYP2C8 results in increased activity of Cyclophosphamide
CYP2C6 results in increased metabolism of Cyclophosphamide		 CTD PMID:9241661 PMID:20566340 PMID:24819615 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157 		JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 decreases metabolic processing
multiple interactions
increases metabolic processing
increases activity
increases hydroxylation
increases response to substance		 ISO CYP2C19 gene polymorphism results in decreased metabolism of Cyclophosphamide
[CYP2C19 protein results in increased hydroxylation of Cyclophosphamide] which results in increased chemical synthesis of 4-hydroxycyclophosphamide; [CYP2C19 protein results in increased hydroxylation of Cyclophosphamide] which results in increased chemical synthesis of Acrolein; CYP2C19 protein polymorphism affects the activity of and affects the susceptibility to Cyclophosphamide
CYP2C19 protein results in increased metabolism of Cyclophosphamide
CYP2C19 results in increased activity of Cyclophosphamide
CYP2C19 protein results in increased susceptibility to Cyclophosphamide		 CTD PMID:9241661 PMID:15248218 PMID:16116487 PMID:30500380 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519 		JBrowse link
G Cyp2c52-ps cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene increases metabolic processing
increases expression
increases response to substance
increases activity
multiple interactions		 ISO CYP2C11 results in increased metabolism of Cyclophosphamide
Cyclophosphamide results in increased expression of CYP2C11 mRNA
CYP2C18 results in increased susceptibility to Cyclophosphamide
CYP2C18 results in increased activity of Cyclophosphamide
POR promotes the reaction [CYP2C18 results in increased susceptibility to Cyclophosphamide]		 CTD PMID:9241661 PMID:9766669 PMID:16019949 PMID:20566340 NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733 		JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 increases metabolic processing
increases response to substance
multiple interactions
increases activity
decreases activity		 ISO
EXP		 CYP2C9 protein results in increased metabolism of Cyclophosphamide
CYP2C9 protein results in increased susceptibility to Cyclophosphamide
[GSTM1 protein co-treated with CYP2C9 protein] results in increased susceptibility to [Busulfan co-treated with Cyclophosphamide]; Sulfaphenazole inhibits the reaction [CYP2C9 protein results in increased susceptibility to Cyclophosphamide]
CYP2C9 results in increased activity of Cyclophosphamide
Cyclophosphamide results in decreased activity of CYP2C9 protein		 CTD PMID:9241661 PMID:10991840 PMID:11377097 PMID:18420780 PMID:24819615 More... NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388 		JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 increases metabolic processing ISO CYP2D6 protein results in increased metabolism of Cyclophosphamide CTD PMID:11377097 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases metabolic processing ISO CYP2E1 results in increased metabolism of Cyclophosphamide CTD PMID:20566340 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 increases expression
affects metabolic processing
multiple interactions
affects response to substance		 EXP
ISO		 Cyclophosphamide results in increased expression of CYP3A13 mRNA
CYP3A5 protein affects the metabolism of Cyclophosphamide
CYP3A5 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin]
CYP3A5 gene polymorphism affects the susceptibility to Cyclophosphamide		 CTD PMID:16087946 PMID:24819615 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
G Cyp3a44 cytochrome P450, family 3, subfamily a, polypeptide 44 decreases activity EXP Cyclophosphamide results in decreased activity of CYP3A4 protein CTD PMID:18420780 NCBI chr 5:145,710,793...145,742,701
Ensembl chr 5:145,710,793...145,742,684 		JBrowse link
G Dcn decorin multiple interactions EXP DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]] CTD PMID:9509296 NCBI chr10:97,315,362...97,354,025
Ensembl chr10:97,315,471...97,354,005 		JBrowse link
G Ddb1 damage specific DNA binding protein 1 increases expression ISO Cyclophosphamide results in increased expression of DDB1 mRNA CTD PMID:11056294 NCBI chr19:10,582,961...10,607,186
Ensembl chr19:10,582,691...10,607,183 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 affects expression
decreases expression
increases expression
multiple interactions		 ISO Cyclophosphamide affects the expression of DDIT3 mRNA
Cyclophosphamide metabolite results in decreased expression of DDIT3 mRNA
Cyclophosphamide results in increased expression of DDIT3 mRNA; Cyclophosphamide results in increased expression of DDIT3 protein
sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased expression of DDIT3 mRNA]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased expression of DDIT3 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of DDIT3 mRNA]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of DDIT3 protein]		 CTD PMID:18246545 PMID:24356939 PMID:32197949 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 affects response to substance ISO DDIT4 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656 		JBrowse link
G Deaf1 DEAF1, transcription factor decreases expression ISO Cyclophosphamide results in decreased expression of DEAF1 mRNA CTD PMID:27281708 NCBI chr 7:140,877,089...140,918,758
Ensembl chr 7:140,877,093...140,907,603 		JBrowse link
G Dlc1 deleted in liver cancer 1 increases expression ISO Cyclophosphamide results in increased expression of DLC1 mRNA CTD PMID:17403535 NCBI chr 8:37,034,893...37,420,343
Ensembl chr 8:37,034,905...37,420,297 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 affects expression
increases expression		 ISO Cyclophosphamide affects the expression of DNAJB1 mRNA
Cyclophosphamide metabolite results in increased expression of DNAJB1 mRNA		 CTD PMID:18246545 PMID:24356939 NCBI chr 8:84,334,804...84,339,282
Ensembl chr 8:84,334,822...84,339,282 		JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Cyclophosphamide metabolite results in increased expression of DNAJB4 mRNA CTD PMID:24356939 NCBI chr 3:151,887,217...151,915,720
Ensembl chr 3:151,884,148...151,915,939 		JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 increases expression ISO Cyclophosphamide results in increased expression of DNAJB6 protein CTD PMID:17475930 NCBI chr 5:29,940,896...29,991,476
Ensembl chr 5:29,940,686...30,023,132 		JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions
decreases methylation
increases expression		 ISO Cyclophosphamide promotes the reaction [KDM1A protein results in decreased methylation of and results in decreased degradation of DNMT1 protein]
Cyclophosphamide results in decreased methylation of DNMT1 protein
Cyclophosphamide results in increased expression of DNMT1 protein		 CTD PMID:22007908 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184 		JBrowse link
G Dntt deoxynucleotidyltransferase, terminal decreases expression EXP Cyclophosphamide results in decreased expression of DNTT mRNA CTD PMID:21041162 NCBI chr19:41,017,701...41,047,964
Ensembl chr19:41,017,714...41,047,964 		JBrowse link
G Dpf3 double PHD fingers 3 decreases expression ISO Cyclophosphamide results in decreased expression of DPF3 mRNA CTD PMID:27281708 NCBI chr12:83,260,525...83,534,510
Ensembl chr12:83,260,519...83,534,490 		JBrowse link
G Dpysl4 dihydropyrimidinase-like 4 increases expression ISO Cyclophosphamide results in increased expression of DPYSL4 mRNA CTD PMID:21527772 NCBI chr 7:138,665,917...138,681,711
Ensembl chr 7:138,665,917...138,682,620 		JBrowse link
G Drd1 dopamine receptor D1 affects binding EXP Cyclophosphamide binds to DRD1 protein CTD PMID:11180191 NCBI chr13:54,205,202...54,209,677
Ensembl chr13:54,205,202...54,209,724 		JBrowse link
G Drd2 dopamine receptor D2 affects binding EXP Cyclophosphamide binds to DRD2 protein CTD PMID:11180191 NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477 		JBrowse link
G Dusp10 dual specificity phosphatase 10 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of DUSP10 mRNA CTD PMID:24356939 NCBI chr 1:183,766,575...183,807,833
Ensembl chr 1:183,745,499...183,807,833 		JBrowse link
G Dusp2 dual specificity phosphatase 2 decreases expression EXP Cyclophosphamide results in decreased expression of DUSP2 mRNA CTD PMID:21041162 NCBI chr 2:127,178,079...127,180,297
Ensembl chr 2:127,178,079...127,180,296 		JBrowse link
G Dzip1 DAZ interacting protein 1 increases expression ISO Cyclophosphamide results in increased expression of DZIP1 mRNA CTD PMID:17403535 NCBI chr14:119,112,927...119,162,947
Ensembl chr14:119,112,932...119,162,872 		JBrowse link
G E2f3 E2F transcription factor 3 multiple interactions ISO E2F3 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr13:30,090,558...30,171,172
Ensembl chr13:30,090,558...30,170,046 		JBrowse link
G Ear6 eosinophil-associated, ribonuclease A family, member 6 decreases expression ISO Cyclophosphamide results in decreased expression of RNASE2 mRNA CTD PMID:17403535 NCBI chr14:52,091,225...52,092,100
Ensembl chr14:52,091,156...52,092,100 		JBrowse link
G Eda2r ectodysplasin A2 receptor increases expression ISO Cyclophosphamide results in increased expression of EDA2R mRNA CTD PMID:21527772 NCBI chr  X:96,375,936...96,420,786
Ensembl chr  X:96,377,446...96,420,822 		JBrowse link
G Edn1 endothelin 1 increases expression ISO Cyclophosphamide results in increased expression of EDN1 protein CTD PMID:17562616 PMID:18548196 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Ednrb endothelin receptor type B increases expression ISO Cyclophosphamide results in increased expression of EDNRB mRNA CTD PMID:20849824 NCBI chr14:104,052,055...104,081,764
Ensembl chr14:104,052,061...104,081,838 		JBrowse link
G Eef2 eukaryotic translation elongation factor 2 decreases expression ISO Cyclophosphamide results in decreased expression of EEF2 mRNA CTD PMID:18246545 NCBI chr10:81,012,465...81,018,343
Ensembl chr10:81,012,465...81,018,332 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO EGFR protein affects the susceptibility to [Cyclophosphamide co-treated with Doxorubicin co-treated with Fluorouracil] CTD PMID:15981280 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
G Egr1 early growth response 1 increases expression
decreases expression
multiple interactions		 ISO
EXP		 Cyclophosphamide results in increased expression of EGR1 mRNA
Cyclophosphamide results in decreased expression of EGR1 mRNA
Cyclophosphamide results in increased expression of EGR1 protein
3-cyanoalanine inhibits the reaction [[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of EGR1 protein]; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of EGR1 protein		 CTD PMID:7498375 PMID:9776515 PMID:21041162 PMID:21527772 PMID:29129814 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037 		JBrowse link
G Egr2 early growth response 2 decreases expression EXP Cyclophosphamide results in decreased expression of EGR2 mRNA CTD PMID:21041162 NCBI chr10:67,370,334...67,383,354
Ensembl chr10:67,371,305...67,378,018 		JBrowse link
G Egr4 early growth response 4 decreases expression ISO Cyclophosphamide results in decreased expression of EGR4 mRNA CTD PMID:27281708 NCBI chr 6:85,488,103...85,490,571
Ensembl chr 6:85,488,103...85,490,571 		JBrowse link
G Eif1ax eukaryotic translation initiation factor 1A, X-linked multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of EIF1AX mRNA CTD PMID:16322899 NCBI chr  X:158,155,174...158,172,617
Ensembl chr  X:158,155,174...158,172,924 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation		 ISO sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased phosphorylation of EIF2AK3 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of EIF2AK3 protein] CTD PMID:32197949 NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of EIF4EBP1 mRNA CTD PMID:16322899 NCBI chr 8:27,750,355...27,765,684
Ensembl chr 8:27,750,357...27,766,702 		JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 affects response to substance ISO ELOVL2 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr13:41,335,858...41,373,879
Ensembl chr13:41,335,857...41,373,881 		JBrowse link
G Emp1 epithelial membrane protein 1 increases expression ISO Cyclophosphamide results in increased expression of EMP1 mRNA CTD PMID:21527772 NCBI chr 6:135,339,548...135,360,171
Ensembl chr 6:135,339,543...135,360,171 		JBrowse link
G Emp3 epithelial membrane protein 3 increases expression ISO Cyclophosphamide results in increased expression of EMP3 mRNA CTD PMID:21527772 NCBI chr 7:45,567,447...45,570,850
Ensembl chr 7:45,567,447...45,570,828 		JBrowse link
G Epb41l2 erythrocyte membrane protein band 4.1 like 2 decreases expression ISO Cyclophosphamide results in decreased expression of EPB41L2 mRNA CTD PMID:17403535 NCBI chr10:25,235,680...25,399,413
Ensembl chr10:25,235,696...25,399,417 		JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal affects expression
increases expression		 ISO Cyclophosphamide affects the expression of EPHX1 mRNA
Cyclophosphamide results in increased expression of EPHX1 mRNA		 CTD PMID:18246545 NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469 		JBrowse link
G Epo erythropoietin multiple interactions
decreases expression
increases response to substance		 ISO angelicae sinensis extract inhibits the reaction [Cyclophosphamide results in decreased expression of EPO mRNA]; Astragali compound inhibits the reaction [Cyclophosphamide results in decreased expression of EPO mRNA]
EPO protein results in increased susceptibility to Cyclophosphamide		 CTD PMID:11245434 PMID:19627214 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504 		JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 increases expression ISO Cyclophosphamide results in increased expression of ERAP1 mRNA CTD PMID:27281708 NCBI chr13:74,787,692...74,841,321
Ensembl chr13:74,787,687...74,841,320 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions ISO ERBB2 affects the susceptibility to [Doxorubicin co-treated with Cyclophosphamide co-treated with docetaxel]; ERBB2 protein affects the susceptibility to [Cyclophosphamide co-treated with Doxorubicin co-treated with docetaxel]; ERBB2 protein affects the susceptibility to [Cyclophosphamide co-treated with pirarubicin co-treated with Fluorouracil]; ERBB2 protein affects the susceptibility to [Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]; ERBB2 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]; ERBB2 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Thiotepa co-treated with Carboplatin] CTD PMID:9816327 PMID:15834928 PMID:15940066 PMID:16446318 PMID:16682728 More... NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 multiple interactions ISO ERBB4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 1:68,071,063...69,147,756
Ensembl chr 1:68,071,345...69,147,218 		JBrowse link
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 affects expression ISO Cyclophosphamide affects the expression of ERCC1 mRNA CTD PMID:11906922 NCBI chr 7:19,079,016...19,090,449
Ensembl chr 7:19,078,703...19,090,449 		JBrowse link
G Ercc2 excision repair cross-complementing rodent repair deficiency, complementation group 2 affects expression
multiple interactions
increases expression		 ISO
EXP		 Cyclophosphamide affects the expression of ERCC2 mRNA
5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline inhibits the reaction [Cyclophosphamide results in increased expression of ERCC2 mRNA]		 CTD PMID:11906922 PMID:30760223 NCBI chr 7:19,115,942...19,129,619
Ensembl chr 7:19,115,935...19,129,619 		JBrowse link
G Erg ETS transcription factor increases expression ISO Cyclophosphamide results in increased expression of ERG mRNA CTD PMID:17403535 NCBI chr16:95,160,028...95,387,452
Ensembl chr16:95,160,028...95,387,452 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signalling 1 increases phosphorylation
multiple interactions		 ISO Cyclophosphamide results in increased phosphorylation of ERN1 protein
sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased phosphorylation of ERN1 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of ERN1 protein]		 CTD PMID:32197949 NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] results in increased expression of ESR1 mRNA CTD PMID:16322899 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] results in increased expression of ESR2 mRNA CTD PMID:16322899 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033 		JBrowse link
G Esrra estrogen related receptor, alpha decreases expression
increases expression		 ISO Cyclophosphamide results in decreased expression of ESRRA mRNA
Cyclophosphamide results in increased expression of ESRRA mRNA		 CTD PMID:27281708 NCBI chr19:6,888,345...6,899,182
Ensembl chr19:6,888,345...6,899,208 		JBrowse link
G Evi2a ecotropic viral integration site 2a decreases expression ISO Cyclophosphamide metabolite results in decreased expression of EVI2A mRNA CTD PMID:24356939 NCBI chr11:79,417,386...79,421,435
Ensembl chr11:79,417,386...79,421,435 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 increases expression ISO Cyclophosphamide results in increased expression of F2RL1 protein CTD PMID:15643279 NCBI chr13:95,648,226...95,661,748
Ensembl chr13:95,648,240...95,661,735 		JBrowse link
G F2rl2 coagulation factor II thrombin receptor like 2 increases expression ISO Cyclophosphamide results in increased expression of F2RL2 protein CTD PMID:15643279 NCBI chr13:95,833,428...95,839,276
Ensembl chr13:95,833,361...95,839,247 		JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 increases expression ISO Cyclophosphamide results in increased expression of F2RL3 protein CTD PMID:15643279 NCBI chr 8:73,488,287...73,490,526
Ensembl chr 8:73,488,508...73,490,502 		JBrowse link
G F3 coagulation factor III decreases expression ISO Cyclophosphamide results in decreased expression of F3 mRNA CTD PMID:17403535 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697 		JBrowse link
G Fam107b family with sequence similarity 107, member B decreases expression ISO Cyclophosphamide metabolite results in decreased expression of FAM107B mRNA CTD PMID:24356939 NCBI chr 2:3,705,049...3,783,179
Ensembl chr 2:3,571,525...3,783,179 		JBrowse link
G Fam234b family with sequence similarity 234, member B multiple interactions ISO FAM234B mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 6:135,173,881...135,213,240
Ensembl chr 6:135,174,975...135,221,953 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression
decreases expression		 ISO
EXP		 [Cyclophosphamide co-treated with cacalol] results in decreased expression of FAS protein; [Cyclophosphamide co-treated with NAc-Sar-Gly-Val-(d-allo-Ile)-Thr-Nva-Ile-Arg-ProNEt] results in increased expression of FAS
Cyclophosphamide results in increased expression of FAS
Cyclophosphamide results in increased expression of FAS mRNA; Cyclophosphamide results in increased expression of FAS protein
Cyclophosphamide metabolite results in decreased expression of FAS mRNA
Plant Extracts inhibits the reaction [Cyclophosphamide results in increased expression of FAS mRNA]		 CTD PMID:10393266 PMID:16166447 PMID:20665104 PMID:24356939 PMID:25446862 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fasl Fas ligand multiple interactions ISO [Cyclophosphamide co-treated with NAc-Sar-Gly-Val-(d-allo-Ile)-Thr-Nva-Ile-Arg-ProNEt] results in increased expression of FASLG CTD PMID:16166447 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064 		JBrowse link
G Fau FAU ubiquitin like and ribosomal protein S30 fusion increases expression ISO Cyclophosphamide results in increased expression of FAU mRNA CTD PMID:11599041 NCBI chr19:6,107,977...6,109,554
Ensembl chr19:6,107,874...6,109,554 		JBrowse link
G Fbxo40 F-box protein 40 increases expression ISO Cyclophosphamide results in increased expression of FBXO40 mRNA CTD PMID:27281708 NCBI chr16:36,783,823...36,811,321
Ensembl chr16:36,783,822...36,810,829 		JBrowse link
G Fbxw7 F-box and WD-40 domain protein 7 increases expression ISO Cyclophosphamide results in increased expression of FBXW7 mRNA CTD PMID:29445054 NCBI chr 3:84,721,901...84,886,505
Ensembl chr 3:84,722,575...84,886,505 		JBrowse link
G Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide increases expression EXP Cyclophosphamide results in increased expression of FCER1G mRNA CTD PMID:21041162 NCBI chr 1:171,057,141...171,061,918
Ensembl chr 1:171,057,141...171,061,934 		JBrowse link
G Fcgr3 Fc receptor, IgG, low affinity III increases expression EXP Cyclophosphamide results in increased expression of FCGR3 mRNA CTD PMID:21041162 NCBI chr 1:170,878,738...170,893,477
Ensembl chr 1:170,878,743...170,892,504 		JBrowse link
G Fcgrt Fc fragment of IgG receptor and transporter increases expression EXP Cyclophosphamide results in increased expression of FCGRT mRNA CTD PMID:21041162 NCBI chr 7:44,742,417...44,753,246
Ensembl chr 7:44,742,414...44,753,275 		JBrowse link
G Fhl1 four and a half LIM domains 1 increases expression ISO Cyclophosphamide results in increased expression of FHL1 mRNA CTD PMID:23558518 NCBI chr  X:55,776,569...55,838,704
Ensembl chr  X:55,777,147...55,838,706 		JBrowse link
G Fkbp1b FK506 binding protein 1b affects response to substance ISO FKBP1B protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr12:4,883,174...4,891,736
Ensembl chr12:4,883,174...4,891,591 		JBrowse link
G Fkbpl FK506 binding protein-like increases expression ISO Cyclophosphamide results in increased expression of FKBPL mRNA CTD PMID:14503796 NCBI chr17:34,863,788...34,865,791
Ensembl chr17:34,863,738...34,865,298 		JBrowse link
G Flnc filamin C, gamma increases expression ISO Cyclophosphamide results in increased expression of FLNC mRNA CTD PMID:21527772 NCBI chr 6:29,433,150...29,461,888
Ensembl chr 6:29,433,255...29,461,882 		JBrowse link
G Flt3l FMS-like tyrosine kinase 3 ligand affects expression EXP Cyclophosphamide affects the expression of FLT3L mRNA CTD PMID:12624490 NCBI chr 7:44,780,607...44,785,914
Ensembl chr 7:44,779,212...44,785,856 		JBrowse link
G Fndc3b fibronectin type III domain containing 3B affects response to substance ISO FNDC3B protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 3:27,470,284...27,765,469
Ensembl chr 3:27,470,311...27,765,456 		JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions
increases expression		 EXP
ISO		 Capsaicin inhibits the reaction [Cyclophosphamide results in increased expression of FOS mRNA]
alfuzosin inhibits the reaction [Cyclophosphamide results in increased expression of FOS protein]; Capsaicin inhibits the reaction [Cyclophosphamide results in increased expression of FOS protein]; resiniferatoxin inhibits the reaction [Cyclophosphamide results in increased expression of FOS protein]		 CTD PMID:7498375 PMID:8801120 PMID:8808730 PMID:9776515 PMID:10749792 More... NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047 		JBrowse link
G Foxp3 forkhead box P3 decreases expression
multiple interactions		 EXP Cyclophosphamide results in decreased expression of FOXP3 mRNA; Cyclophosphamide results in decreased expression of FOXP3 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of FOXP3 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of FOXP3 protein]		 CTD PMID:15591121 PMID:32151603 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Foxp4 forkhead box P4 decreases expression ISO Cyclophosphamide results in decreased expression of FOXP4 mRNA CTD PMID:27281708 NCBI chr17:48,178,058...48,235,401
Ensembl chr17:48,178,058...48,235,570 		JBrowse link
G Fpr2 formyl peptide receptor 2 increases expression EXP Cyclophosphamide results in increased expression of FPR2 mRNA CTD PMID:15331540 NCBI chr17:18,108,086...18,114,214
Ensembl chr17:18,108,086...18,114,214 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 increases expression ISO Cyclophosphamide results in increased expression of FSCN1 mRNA CTD PMID:17403535 NCBI chr 5:142,946,110...142,958,944
Ensembl chr 5:142,946,098...142,958,940 		JBrowse link
G Fshb follicle stimulating hormone beta increases expression
decreases secretion
multiple interactions		 ISO Cyclophosphamide results in increased expression of FSHB protein
Cyclophosphamide results in decreased secretion of FSHB protein
Cilostazol inhibits the reaction [Cyclophosphamide results in increased expression of FSHB protein]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in decreased secretion of FSHB protein]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased secretion of FSHB protein]		 CTD PMID:6788612 PMID:25446862 PMID:32197949 PMID:32456565 NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001 		JBrowse link
G Fshr follicle stimulating hormone receptor multiple interactions
decreases expression		 EXP coenzyme Q10 inhibits the reaction [Cyclophosphamide results in decreased expression of FSHR mRNA] CTD PMID:31557371 NCBI chr17:89,292,380...89,508,103
Ensembl chr17:89,292,380...89,508,103 		JBrowse link
G Fyn Fyn proto-oncogene increases expression ISO Cyclophosphamide results in increased expression of FYN mRNA CTD PMID:17403535 NCBI chr10:39,245,735...39,441,377
Ensembl chr10:39,244,851...39,441,377 		JBrowse link
G G3bp1 G3BP stress granule assembly factor 1 decreases expression EXP Cyclophosphamide results in decreased expression of G3BP1 mRNA CTD PMID:21041162 NCBI chr11:55,360,521...55,391,722
Ensembl chr11:55,360,511...55,395,664 		JBrowse link
G G6pc2 glucose-6-phosphatase, catalytic, 2 decreases expression EXP Cyclophosphamide results in decreased expression of G6PC2 mRNA CTD PMID:15331540 NCBI chr 2:69,041,417...69,058,337
Ensembl chr 2:69,041,417...69,058,185 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha increases expression
affects expression		 ISO Cyclophosphamide results in increased expression of GADD45A mRNA
Cyclophosphamide affects the expression of GADD45A mRNA		 CTD PMID:18246545 PMID:29445054 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441 		JBrowse link
G Gal galanin and GMAP prepropeptide affects expression
increases expression		 ISO
EXP		 Cyclophosphamide affects the expression of GAL mRNA; Cyclophosphamide affects the expression of GAL protein
Cyclophosphamide results in increased expression of GAL mRNA		 CTD PMID:16491427 PMID:17335920 PMID:18563302 NCBI chr19:3,459,915...3,464,544
Ensembl chr19:3,459,915...3,464,544 		JBrowse link
G Galc galactosylceramidase affects response to substance ISO GALC protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr12:98,168,543...98,226,565
Ensembl chr12:98,168,553...98,225,718 		JBrowse link
G Gamt guanidinoacetate methyltransferase multiple interactions ISO GAMT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr10:80,093,985...80,096,846
Ensembl chr10:80,093,985...80,096,846 		JBrowse link
G Gap43 growth associated protein 43 increases expression ISO Cyclophosphamide results in increased expression of GAP43 protein CTD PMID:9486479 PMID:10536274 NCBI chr16:42,068,915...42,161,014
Ensembl chr16:42,068,805...42,161,014 		JBrowse link
G Gas2 growth arrest specific 2 increases expression ISO Cyclophosphamide results in increased expression of GAS2 protein CTD PMID:17475930 NCBI chr 7:51,511,560...51,644,753
Ensembl chr 7:51,511,763...51,644,723 		JBrowse link
G Gata3 GATA binding protein 3 decreases expression
multiple interactions		 EXP Cyclophosphamide results in decreased expression of GATA3 mRNA; Cyclophosphamide results in decreased expression of GATA3 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of GATA3 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of GATA3 protein]		 CTD PMID:21041162 PMID:32151603 NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845 		JBrowse link
G Gbp2b guanylate binding protein 2b increases expression EXP Cyclophosphamide results in increased expression of GBP1 mRNA CTD PMID:21621594 NCBI chr 3:142,300,577...142,324,940
Ensembl chr 3:142,300,608...142,324,940 		JBrowse link
G Gbp3 guanylate binding protein 3 increases expression EXP Cyclophosphamide results in increased expression of GBP3 mRNA CTD PMID:15331540 NCBI chr 3:142,265,781...142,278,974
Ensembl chr 3:142,265,787...142,278,970 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
decreases expression		 EXP Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of GCLC protein]
Cyclophosphamide results in decreased expression of GCLC mRNA; Cyclophosphamide results in decreased expression of GCLC protein		 CTD PMID:27633142 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767 		JBrowse link
G Gdnf glial cell line derived neurotrophic factor increases expression ISO Cyclophosphamide results in increased expression of GDNF mRNA CTD PMID:10683293 NCBI chr15:7,839,529...7,867,061
Ensembl chr15:7,840,327...7,867,056 		JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle increases expression EXP Cyclophosphamide results in increased expression of GEM mRNA CTD PMID:21041162 NCBI chr 4:11,702,379...11,714,993
Ensembl chr 4:11,704,457...11,714,752 		JBrowse link
G Gfi1 growth factor independent 1 transcription repressor decreases expression EXP Cyclophosphamide results in decreased expression of GFI1 mRNA CTD PMID:21041162 NCBI chr 5:107,864,521...107,873,671
Ensembl chr 5:107,864,523...107,873,902 		JBrowse link
G Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 multiple interactions ISO GFRA1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr19:58,224,013...58,444,387
Ensembl chr19:58,224,036...58,444,341 		JBrowse link
G Gimap4 GTPase, IMAP family member 4 decreases expression ISO Cyclophosphamide results in decreased expression of GIMAP4 mRNA CTD PMID:27466211 NCBI chr 6:48,661,453...48,668,996
Ensembl chr 6:48,661,483...48,668,994 		JBrowse link
G Gja1 gap junction protein, alpha 1 affects expression ISO Cyclophosphamide affects the expression of GJA1 mRNA CTD PMID:10859244 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609 		JBrowse link
G Gjb1 gap junction protein, beta 1 decreases expression EXP Cyclophosphamide results in decreased expression of GJB1 mRNA CTD PMID:21621594 NCBI chr  X:100,419,982...100,429,235
Ensembl chr  X:100,419,984...100,429,235 		JBrowse link
G Glis1 GLIS family zinc finger 1 decreases expression ISO Cyclophosphamide results in decreased expression of GLIS1 mRNA CTD PMID:27281708 NCBI chr 4:107,283,840...107,492,258
Ensembl chr 4:107,291,788...107,492,258 		JBrowse link
G Glod4 glyoxalase domain containing 4 decreases expression ISO Cyclophosphamide results in decreased expression of GLOD4 mRNA CTD PMID:20849824 NCBI chr11:76,111,221...76,134,525
Ensembl chr11:76,011,813...76,134,551 		JBrowse link
G Glrb glycine receptor, beta subunit increases expression ISO Cyclophosphamide results in increased expression of GLRB mRNA CTD PMID:17403535 NCBI chr 3:80,750,905...80,820,994
Ensembl chr 3:80,750,906...80,820,967 		JBrowse link
G Gls glutaminase increases expression
affects response to substance		 ISO Cyclophosphamide results in increased expression of GLS mRNA
GLS protein affects the susceptibility to Cyclophosphamide		 CTD PMID:16217747 PMID:21527772 NCBI chr 1:52,202,608...52,274,168
Ensembl chr 1:52,202,607...52,272,391 		JBrowse link
G Gm40318 predicted gene, 40318 affects response to substance
decreases expression		 ISO S100P protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in decreased expression of S100P mRNA		 CTD PMID:16217747 PMID:17403535 NCBI chr 5:36,919,848...36,924,763
Ensembl chr 5:36,919,961...36,924,039 		JBrowse link
G Gm7030 predicted gene 7030 increases expression ISO Cyclophosphamide results in increased expression of HLA-F mRNA CTD PMID:20849824 NCBI chr17:36,438,501...36,440,317
Ensembl chr17:36,420,611...36,440,317 		JBrowse link
G Gng12 guanine nucleotide binding protein (G protein), gamma 12 increases expression ISO Cyclophosphamide results in increased expression of GNG12 mRNA CTD PMID:17403535 NCBI chr 6:66,873,381...66,998,345
Ensembl chr 6:66,873,381...66,998,334 		JBrowse link
G Gpatch8 G patch domain containing 8 increases expression ISO Cyclophosphamide results in increased expression of GPATCH8 mRNA CTD PMID:27281708 NCBI chr11:102,366,737...102,447,217
Ensembl chr11:102,366,741...102,447,218 		JBrowse link
G Gpr137b G protein-coupled receptor 137B increases expression ISO Cyclophosphamide results in increased expression of GPR137B mRNA CTD PMID:21527772 NCBI chr13:13,528,035...13,568,250
Ensembl chr13:13,532,205...13,568,599 		JBrowse link
G Gpr18 G protein-coupled receptor 18 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of GPR18 mRNA CTD PMID:24356939 NCBI chr14:122,148,846...122,153,300
Ensembl chr14:122,148,665...122,153,193 		JBrowse link
G Gpr20 G protein-coupled receptor 20 increases expression ISO Cyclophosphamide results in increased expression of GPR20 mRNA CTD PMID:20849824 NCBI chr15:73,560,346...73,579,354
Ensembl chr15:73,566,453...73,579,354 		JBrowse link
G Gpt glutamic pyruvic transaminase, soluble increases expression
increases activity
multiple interactions
affects activity		 ISO
EXP		 Cyclophosphamide results in increased expression of GPT protein
Cyclophosphamide results in increased activity of GPT protein
naringin affects the reaction [Cyclophosphamide affects the activity of GPT protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased activity of GPT protein]; Rutin inhibits the reaction [Cyclophosphamide results in increased activity of GPT protein]; Vitamin E inhibits the reaction [Cyclophosphamide results in increased expression of GPT protein]
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased activity of GPT protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased activity of GPT protein]		 CTD PMID:25753322 PMID:25779342 PMID:29753871 PMID:30506662 PMID:33992719 More... NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886 		JBrowse link
G Gpt2 glutamic pyruvate transaminase (alanine aminotransferase) 2 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of GPT2 mRNA CTD PMID:24356939 NCBI chr 8:86,219,090...86,255,531
Ensembl chr 8:86,219,205...86,254,189 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression
multiple interactions
decreases activity		 EXP
ISO		 Cyclophosphamide results in decreased expression of GPX1 mRNA
Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of GPX1 mRNA]
Quercetin inhibits the reaction [Cyclophosphamide results in decreased activity of GPX1 protein]		 CTD PMID:23542512 PMID:35906875 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542 		JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression EXP Cyclophosphamide results in increased expression of GPX3 mRNA CTD PMID:21041162 NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203 		JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression
decreases expression
multiple interactions		 ISO
EXP		 Cyclophosphamide results in increased expression of GPX4 protein
Cyclophosphamide results in decreased expression of GPX4 protein
Dexrazoxane inhibits the reaction [Cyclophosphamide results in decreased expression of GPX4 protein]		 CTD PMID:17475930 PMID:37690746 NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273 		JBrowse link
G Gsr glutathione reductase multiple interactions
decreases activity		 EXP
ISO		 [[Cyclophosphamide co-treated with Cisplatin co-treated with Carmustine] results in decreased activity of GSR protein] which results in increased abundance of Glutathione Disulfide; [Cyclophosphamide co-treated with Cisplatin co-treated with Carmustine] results in decreased activity of GSR protein; Buthionine Sulfoximine promotes the reaction [Cyclophosphamide results in decreased activity of GSR protein]; Plant Extracts inhibits the reaction [Buthionine Sulfoximine promotes the reaction [Cyclophosphamide results in decreased activity of GSR protein]]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased activity of GSR protein]
naringin inhibits the reaction [Cyclophosphamide results in decreased activity of GSR protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased activity of GSR protein]; Rutin inhibits the reaction [Cyclophosphamide results in decreased activity of GSR protein]		 CTD PMID:12114195 PMID:21772021 PMID:23542512 PMID:25446862 PMID:25753322 More... NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191 		JBrowse link
G Gstm1 glutathione S-transferase, mu 1 multiple interactions ISO [GSTM1 protein co-treated with CYP2C9 protein] results in increased susceptibility to [Busulfan co-treated with Cyclophosphamide]; GSTM1 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin] CTD PMID:16087946 PMID:28744217 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289 		JBrowse link
G Gstm2 glutathione S-transferase, mu 2 decreases expression ISO Cyclophosphamide results in decreased expression of GSTM2 mRNA CTD PMID:11906922 NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769 		JBrowse link
G Gstp1 glutathione S-transferase, pi 1 multiple interactions
increases expression
affects response to substance
decreases response to substance		 ISO
EXP		 GSTP1 gene SNP results in increased susceptibility to [Carmustine co-treated with Doxorubicin co-treated with Cyclophosphamide co-treated with Melphalan]
Cyclophosphamide results in increased expression of GSTP1 mRNA; Cyclophosphamide results in increased expression of GSTP1 protein
GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]; Mesna inhibits the reaction [GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]]
GSTP1 protein affects the susceptibility to Cyclophosphamide
GSTP1 protein results in decreased susceptibility to Cyclophosphamide		 CTD PMID:10954901 PMID:12791655 PMID:16141653 PMID:16242832 PMID:19696094 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985 		JBrowse link
G Gstp2 glutathione S-transferase, pi 2 multiple interactions
affects response to substance		 EXP GSTP2 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]; Mesna inhibits the reaction [GSTP2 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]]
GSTP2 protein affects the susceptibility to Cyclophosphamide		 CTD PMID:19696094 NCBI chr19:4,090,288...4,092,221
Ensembl chr19:4,090,285...4,096,023 		JBrowse link
G Gtf2b general transcription factor IIB increases expression ISO Cyclophosphamide results in increased expression of GTF2B mRNA CTD PMID:27281708 NCBI chr 3:142,471,008...142,489,367
Ensembl chr 3:142,470,806...142,489,367 		JBrowse link
G Gtf3c1 general transcription factor III C 1 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of GTF3C1 mRNA CTD PMID:16322899 NCBI chr 7:125,240,126...125,306,860
Ensembl chr 7:125,240,126...125,306,952 		JBrowse link
G Gusb glucuronidase, beta decreases expression
multiple interactions
increases activity		 ISO Cyclophosphamide results in decreased expression of GUSB protein
Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of GUSB protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased activity of GUSB protein]		 CTD PMID:17686619 PMID:25451569 NCBI chr 5:130,011,278...130,031,890
Ensembl chr 5:130,017,852...130,031,890 		JBrowse link
G Gzma granzyme A decreases expression EXP Cyclophosphamide results in decreased expression of GZMA mRNA CTD PMID:21041162 NCBI chr13:113,230,358...113,237,515
Ensembl chr13:113,230,359...113,237,515 		JBrowse link
G Gzmb granzyme B increases expression EXP Cyclophosphamide results in increased expression of GZMB mRNA CTD PMID:15331540 NCBI chr14:56,496,293...56,499,791
Ensembl chr14:56,496,295...56,499,717 		JBrowse link
G H13 histocompatibility 13 decreases expression EXP Cyclophosphamide results in decreased expression of H13 mRNA CTD PMID:15331540 NCBI chr 2:152,511,292...152,550,590
Ensembl chr 2:152,511,381...152,550,590 		JBrowse link
G H2-K1 histocompatibility 2, K1, K region increases expression EXP Cyclophosphamide results in increased expression of H2-K1 mRNA CTD PMID:21041162 NCBI chr17:34,214,986...34,219,316
Ensembl chr17:34,214,991...34,219,321 		JBrowse link
G H2ax H2A.X variant histone increases phosphorylation
increases expression
multiple interactions		 ISO
EXP		 Cyclophosphamide results in increased phosphorylation of H2AX protein
Cyclophosphamide results in increased expression of H2AX protein
Dexrazoxane inhibits the reaction [Cyclophosphamide results in increased expression of H2AX protein]		 CTD PMID:32482060 PMID:33211169 PMID:34510228 PMID:37690746 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions
decreases expression		 ISO O-1602 compound inhibits the reaction [Cyclophosphamide results in decreased expression of HBEGF protein] CTD PMID:32615180 NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858 		JBrowse link
G Hcrt hypocretin affects localization
decreases expression		 ISO Cyclophosphamide affects the localization of HCRT protein
Cyclophosphamide results in decreased expression of HCRT mRNA		 CTD PMID:17881193 PMID:19666069 NCBI chr11:100,652,519...100,653,757
Ensembl chr11:100,651,895...100,653,757 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit increases expression EXP Cyclophosphamide results in increased expression of HIF1A mRNA CTD PMID:15331540 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Hinfp histone H4 transcription factor decreases expression ISO Cyclophosphamide results in decreased expression of HINFP mRNA CTD PMID:27281708 NCBI chr 9:44,201,509...44,217,003
Ensembl chr 9:44,203,737...44,216,968 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 increases expression ISO Cyclophosphamide metabolite results in increased expression of HMGCS1 mRNA CTD PMID:24356939 NCBI chr13:120,151,887...120,169,796
Ensembl chr13:120,151,915...120,169,796 		JBrowse link
G Hmox1 heme oxygenase 1 affects expression
increases expression
multiple interactions
decreases expression		 ISO Cyclophosphamide affects the expression of HMOX1 mRNA
Cyclophosphamide results in increased expression of HMOX1 mRNA; Cyclophosphamide results in increased expression of HMOX1 protein
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of HMOX1 protein; Cilostazol inhibits the reaction [Cyclophosphamide results in decreased expression of HMOX1 mRNA]; Cilostazol inhibits the reaction [Cyclophosphamide results in decreased expression of HMOX1 protein]; Hemin inhibits the reaction [Cyclophosphamide results in increased expression of HMOX1 mRNA]; Hemin promotes the reaction [Cyclophosphamide results in increased expression of HMOX1 mRNA]; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of HMOX1 protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of HMOX1 mRNA]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in decreased expression of HMOX1 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased expression of HMOX1 protein]
Cyclophosphamide results in decreased expression of HMOX1 mRNA; Cyclophosphamide results in decreased expression of HMOX1 protein		 CTD PMID:11906922 PMID:17979934 PMID:18206168 PMID:18246545 PMID:19952508 More... NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hmox2 heme oxygenase 2 decreases expression ISO Cyclophosphamide results in decreased expression of HMOX2 mRNA CTD PMID:11906922 NCBI chr16:4,544,225...4,584,606
Ensembl chr16:4,544,225...4,584,606 		JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K increases expression ISO Cyclophosphamide results in increased expression of HNRNPK protein
Cyclophosphamide results in increased expression of HNRNPK mRNA		 CTD PMID:11599041 PMID:17475930 NCBI chr13:58,538,946...58,551,157
Ensembl chr13:58,538,956...58,551,157 		JBrowse link
G Hoxa1 homeobox A1 affects response to substance ISO HOXA1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 6:52,132,573...52,135,299
Ensembl chr 6:52,132,570...52,135,297 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases mutagenesis EXP
ISO		 Cyclophosphamide results in increased mutagenesis of HPRT1 gene CTD PMID:17116724 PMID:23677247 NCBI chr  X:52,076,955...52,110,537
Ensembl chr  X:52,077,014...52,110,536 		JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 decreases expression ISO Cyclophosphamide results in decreased expression of HSP90AA1 mRNA CTD PMID:11906922 NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 decreases expression ISO Cyclophosphamide results in decreased expression of HSP90AB1 mRNA CTD PMID:11906922 NCBI chr17:45,878,704...45,884,187
Ensembl chr17:45,878,701...45,884,197 		JBrowse link
G Hsp90b1 heat shock protein 90, beta (Grp94), member 1 decreases expression
increases expression		 ISO Cyclophosphamide results in decreased expression of HSP90B1 mRNA
Cyclophosphamide results in increased expression of HSP90B1 mRNA		 CTD PMID:11599041 PMID:11906922 NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373 		JBrowse link
G Hspa1a heat shock protein 1A increases expression
affects expression		 ISO Cyclophosphamide results in increased expression of HSPA1A mRNA; Cyclophosphamide results in increased expression of HSPA1A protein
Cyclophosphamide affects the expression of HSPA1A mRNA		 CTD PMID:8917683 PMID:18246545 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132 		JBrowse link
G Hspa1b heat shock protein 1B decreases expression
affects expression
increases expression		 ISO Cyclophosphamide results in decreased expression of HSPA1B mRNA
Cyclophosphamide affects the expression of HSPA1B mRNA
Cyclophosphamide metabolite results in increased expression of HSPA1B mRNA		 CTD PMID:16141653 PMID:18246545 PMID:24356939 NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214 		JBrowse link
G Hspa2 heat shock protein 2 affects response to substance
increases expression		 ISO HSPA2 protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in increased expression of HSPA2 mRNA		 CTD PMID:11599041 PMID:16217747 NCBI chr12:76,450,688...76,453,712
Ensembl chr12:76,450,950...76,453,712 		JBrowse link
G Hspa5 heat shock protein 5 decreases expression
increases expression		 ISO Cyclophosphamide results in decreased expression of HSPA5 mRNA
Cyclophosphamide metabolite results in increased expression of HSPA5 mRNA		 CTD PMID:11906922 PMID:24356939 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559 		JBrowse link
G Hspa8 heat shock protein 8 affects response to substance ISO HSPA8 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383 		JBrowse link
G Hspa9 heat shock protein 9 decreases expression ISO Cyclophosphamide results in decreased expression of HSPA9 mRNA CTD PMID:11906922 NCBI chr18:35,070,467...35,087,404
Ensembl chr18:35,070,467...35,087,410 		JBrowse link
G Hspb1 heat shock protein 1 decreases expression
increases expression		 ISO Cyclophosphamide results in decreased expression of HSPB1 mRNA
Cyclophosphamide results in increased expression of HSPB1 mRNA		 CTD PMID:11599041 PMID:11906922 PMID:18246545 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417 		JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) decreases expression ISO Cyclophosphamide results in decreased expression of HSPD1 mRNA CTD PMID:11906922 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402 		JBrowse link
G Hspe1 heat shock protein 1 (chaperonin 10) decreases expression ISO Cyclophosphamide results in decreased expression of HSPE1 mRNA CTD PMID:11906922 NCBI chr 1:55,127,307...55,130,476
Ensembl chr 1:55,127,291...55,130,466 		JBrowse link
G Hsph1 heat shock 105kDa/110kDa protein 1 increases expression ISO Cyclophosphamide metabolite results in increased expression of HSPH1 mRNA CTD PMID:24356939 NCBI chr 5:149,540,308...149,562,594
Ensembl chr 5:149,537,752...149,559,841 		JBrowse link
G Hyls1 HYLS1, centriolar and ciliogenesis associated decreases expression ISO Cyclophosphamide metabolite results in decreased expression of HYLS1 mRNA CTD PMID:24356939 NCBI chr 9:35,472,117...35,481,365
Ensembl chr 9:35,472,116...35,481,694 		JBrowse link
G Hyou1 hypoxia up-regulated 1 decreases expression ISO Cyclophosphamide results in decreased expression of HYOU1 mRNA CTD PMID:11906922 NCBI chr 9:44,290,840...44,303,662
Ensembl chr 9:44,290,787...44,303,666 		JBrowse link
G Ica1 islet cell autoantigen 1 affects response to substance EXP ICA1 protein affects the susceptibility to Cyclophosphamide CTD PMID:11751995 NCBI chr 6:8,630,527...8,778,531
Ensembl chr 6:8,630,527...8,778,488 		JBrowse link
G Icam1 intercellular adhesion molecule 1 affects response to substance
multiple interactions		 EXP ICAM1 protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide inhibits the reaction [Paraquat results in increased expression of ICAM1 mRNA]		 CTD PMID:11591119 PMID:36031164 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of ID2 mRNA CTD PMID:24356939 NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase increases expression ISO Cyclophosphamide metabolite results in increased expression of IDI1 mRNA CTD PMID:24356939 NCBI chr13:8,935,642...8,942,432
Ensembl chr13:8,935,537...8,942,487 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 increases expression
multiple interactions		 ISO Cyclophosphamide results in increased expression of IDO1 protein
Cyclophosphamide results in increased expression of and results in increased activity of IDO1 protein; Quercetin inhibits the reaction [Cyclophosphamide results in increased activity of IDO1 protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of and results in increased activity of IDO1 protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of IDO1 protein]		 CTD PMID:34748891 PMID:35906875 NCBI chr 8:25,074,148...25,086,987
Ensembl chr 8:25,074,152...25,087,025 		JBrowse link
G Ier3 immediate early response 3 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of IER3 mRNA CTD PMID:24356939 NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815 		JBrowse link
G Ier5 immediate early response 5 increases expression ISO Cyclophosphamide results in increased expression of IER5 mRNA CTD PMID:21527772 NCBI chr 1:154,972,113...154,975,382
Ensembl chr 1:154,972,107...154,975,382 		JBrowse link
G Ifi202b interferon activated gene 202B increases expression EXP Cyclophosphamide results in increased expression of IFI202B mRNA CTD PMID:15331540 NCBI chr 1:173,790,135...173,810,410
Ensembl chr 1:173,790,134...173,810,310 		JBrowse link
G Ifi204 interferon activated gene 204 increases expression EXP Cyclophosphamide results in increased expression of IFI204 mRNA CTD PMID:21041162 NCBI chr 1:173,574,859...173,594,606
Ensembl chr 1:173,574,859...173,594,509 		JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression EXP Cyclophosphamide results in increased expression of IFIT2 mRNA CTD PMID:15331540 NCBI chr19:34,527,961...34,553,934
Ensembl chr19:34,528,094...34,553,819 		JBrowse link
G Ifna1 interferon alpha 1 multiple interactions
increases expression		 ISO naringin inhibits the reaction [Cyclophosphamide results in increased expression of IFNA1 mRNA] CTD PMID:33992719 NCBI chr 4:88,768,324...88,768,893
Ensembl chr 4:88,768,324...88,768,893 		JBrowse link
G Ifng interferon gamma affects expression
multiple interactions
increases expression
decreases expression
decreases secretion		 EXP
ISO		 Cyclophosphamide affects the expression of IFNG mRNA
(4-formyl-9-methoxy-5-methyl-naphtho(2,3-b)furan-3-yl)methyl acetate inhibits the reaction [Cyclophosphamide results in decreased secretion of IFNG protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IFNG mRNA]; ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of IFNG protein]; IFNG protein inhibits the reaction [Cyclophosphamide results in increased abundance of Nitric Oxide]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IFNG mRNA]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IFNG protein]
Cyclophosphamide results in increased expression of IFNG protein
Cyclophosphamide results in decreased expression of IFNG mRNA; Cyclophosphamide results in decreased expression of IFNG protein
Cyclophosphamide results in increased expression of IFNG mRNA
[Cyclophosphamide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA
Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of IFNG protein]		 CTD PMID:10607705 PMID:11006010 PMID:11014644 PMID:15331540 PMID:18848347 More... NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Ifngr1 interferon gamma receptor 1 decreases expression EXP Cyclophosphamide results in decreased expression of IFNGR1 mRNA CTD PMID:21041162 NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977 		JBrowse link
G Ifrd1 interferon-related developmental regulator 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of IFRD1 mRNA CTD PMID:24356939 NCBI chr12:40,253,128...40,273,184
Ensembl chr12:40,251,566...40,298,503 		JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 affects response to substance ISO IGF2BP3 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 6:49,062,152...49,200,225
Ensembl chr 6:49,062,157...49,191,891 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 affects response to substance
decreases expression		 ISO IGFBP3 protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in decreased expression of IGFBP3 mRNA		 CTD PMID:16141653 PMID:16217747 NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 multiple interactions ISO IGFBP4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr11:98,930,820...98,943,481
Ensembl chr11:98,932,070...98,945,218 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression EXP
ISO		 Cyclophosphamide results in decreased expression of IGFBP5 mRNA CTD PMID:15331540 PMID:20849824 NCBI chr 1:72,897,224...72,914,024
Ensembl chr 1:72,897,091...72,914,043 		JBrowse link
G Igh-VJ558 immunoglobulin heavy chain (J558 family) decreases expression EXP Cyclophosphamide results in decreased expression of IGH-VJ558 mRNA CTD PMID:15331540
G Igha immunoglobulin heavy constant alpha multiple interactions
decreases expression		 EXP ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of IGHA protein] CTD PMID:37853057 NCBI chr12:113,219,824...113,223,856
Ensembl chr12:113,218,450...113,223,856 		JBrowse link
G Ighg1 immunoglobulin heavy constant gamma 1 (G1m marker) decreases expression
multiple interactions		 EXP Cyclophosphamide results in decreased expression of IGHG1 protein
ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of IGHG1 protein]		 CTD PMID:37853057 NCBI chr12:113,290,161...113,294,143
Ensembl chr12:113,288,860...113,294,143 		JBrowse link
G Ighv7-1 immunoglobulin heavy variable 7-1 decreases expression EXP Cyclophosphamide results in decreased expression of IGH-V mRNA CTD PMID:15331540 NCBI chr12:113,860,028...113,860,566
Ensembl chr12:113,860,028...113,860,566 		JBrowse link
G Igkc immunoglobulin kappa constant decreases expression EXP Cyclophosphamide results in decreased expression of IGKC mRNA CTD PMID:15331540 NCBI chr 6:70,703,419...70,703,738
Ensembl chr 6:70,703,419...70,703,950 		JBrowse link
G Il10 interleukin 10 decreases expression
increases expression
multiple interactions		 EXP
ISO		 Cyclophosphamide results in decreased expression of IL10 mRNA
Cyclophosphamide results in increased expression of IL10 protein
Cyclophosphamide results in increased expression of IL10 mRNA
Cyclophosphamide results in decreased expression of IL10 protein
Anthocyanins inhibits the reaction [Cyclophosphamide results in decreased expression of IL10 protein]; chrysin inhibits the reaction [Cyclophosphamide results in increased expression of IL10 protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of IL10 protein]
[Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL10 protein		 CTD PMID:11014644 PMID:11948286 PMID:18848347 PMID:21068404 PMID:25451569 More... NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il12a interleukin 12a multiple interactions
decreases expression		 EXP [Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of [IL12A protein binds to IL12B protein]; ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of IL12A protein] CTD PMID:29228376 PMID:37853057 NCBI chr 3:68,597,977...68,605,881
Ensembl chr 3:68,597,977...68,605,880 		JBrowse link
G Il12b interleukin 12b affects expression
increases expression
multiple interactions
decreases expression		 EXP
ISO		 Cyclophosphamide affects the expression of IL12B mRNA
Cyclophosphamide results in increased expression of IL12B mRNA
[Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of [IL12A protein binds to IL12B protein]; ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of IL12B protein]
Cyclophosphamide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein]		 CTD PMID:15331540 PMID:18957084 PMID:22842586 PMID:29228376 PMID:36416909 More... NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860 		JBrowse link
G Il13ra1 interleukin 13 receptor, alpha 1 increases expression EXP Cyclophosphamide results in increased expression of IL13RA1 mRNA CTD PMID:21041162 NCBI chr  X:35,375,761...35,434,915
Ensembl chr  X:35,375,763...35,434,912 		JBrowse link
G Il15 interleukin 15 multiple interactions
decreases secretion		 EXP (4-formyl-9-methoxy-5-methyl-naphtho(2,3-b)furan-3-yl)methyl acetate inhibits the reaction [Cyclophosphamide results in decreased secretion of IL15 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IL15 protein] CTD PMID:23395935 NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851 		JBrowse link
G Il15ra interleukin 15 receptor, alpha chain increases expression EXP Cyclophosphamide results in increased expression of IL15RA mRNA CTD PMID:21041162 NCBI chr 2:11,709,992...11,739,129
Ensembl chr 2:11,710,101...11,739,128 		JBrowse link
G Il16 interleukin 16 decreases expression EXP Cyclophosphamide results in decreased expression of IL16 mRNA CTD PMID:21041162 NCBI chr 7:83,292,027...83,395,479
Ensembl chr 7:83,292,033...83,394,934 		JBrowse link
G Il17a interleukin 17A decreases expression
multiple interactions		 EXP Cyclophosphamide results in decreased expression of IL17A protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL17A protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL17A protein]		 CTD PMID:21880982 PMID:32151603 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720 		JBrowse link
G Il18 interleukin 18 increases expression ISO Cyclophosphamide results in increased expression of IL18 protein CTD PMID:18848347 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il1a interleukin 1 alpha increases expression
affects response to substance
multiple interactions		 EXP
ISO		 Cyclophosphamide results in increased expression of IL1A mRNA
IL1A promoter polymorphism affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in increased expression of IL1A protein
[Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL1A protein		 CTD PMID:15331540 PMID:16636934 PMID:18848347 PMID:31651976 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
increases response to substance
decreases expression
increases secretion		 EXP
ISO		 Cyclophosphamide results in increased expression of IL1B mRNA; Cyclophosphamide results in increased expression of IL1B protein
allyl sulfide inhibits the reaction [Cyclophosphamide results in increased secretion of IL1B protein]; Anthocyanins inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Bilirubin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B mRNA]; chrysin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Cilostazol inhibits the reaction [Cyclophosphamide results in increased expression of IL1B mRNA]; naringin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B mRNA]; Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]]; O-1602 compound inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Pentoxifylline inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Rolipram inhibits the reaction [Cyclophosphamide results in increased expression of IL1B mRNA]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]
[Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL1B protein; [Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of IL1B protein; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL1B protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL1B protein]; VIP protein inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]
IL1B protein results in increased susceptibility to Cyclophosphamide		 CTD PMID:8634684 PMID:11948286 PMID:15331540 PMID:18206168 PMID:18483878 More... NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il1r1 interleukin 1 receptor, type I increases expression
multiple interactions		 ISO Cyclophosphamide results in increased expression of IL1R1 mRNA
naringin inhibits the reaction [Cyclophosphamide results in increased expression of IL1R1 mRNA]		 CTD PMID:33992719 NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417 		JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression EXP Cyclophosphamide results in increased expression of IL1RN mRNA CTD PMID:15331540 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Il2 interleukin 2 increases expression
decreases expression
multiple interactions
decreases secretion		 EXP
ISO		 Cyclophosphamide results in increased expression of IL2 mRNA
Cyclophosphamide results in decreased expression of IL2 protein
(4-formyl-9-methoxy-5-methyl-naphtho(2,3-b)furan-3-yl)methyl acetate inhibits the reaction [Cyclophosphamide results in decreased secretion of IL2 protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL2 mRNA]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL2 mRNA]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IL2 protein]		 CTD PMID:11006010 PMID:11948286 PMID:18848347 PMID:23395935 PMID:32151603 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108 		JBrowse link
G Il21 interleukin 21 multiple interactions
decreases expression		 EXP Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL21 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL21 protein] CTD PMID:32151603 NCBI chr 3:37,276,908...37,286,785
Ensembl chr 3:37,276,908...37,286,785 		JBrowse link
G Il23a interleukin 23, alpha subunit p19 decreases secretion
multiple interactions
decreases expression		 EXP Cyclophosphamide results in decreased secretion of IL23A protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL23A protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL23A protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IL23A protein]		 CTD PMID:23395935 PMID:32151603 NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621 		JBrowse link
G Il3 interleukin 3 multiple interactions EXP [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL3 protein CTD PMID:31651976 NCBI chr11:54,155,911...54,158,105
Ensembl chr11:54,156,129...54,158,103 		JBrowse link
G Il4 interleukin 4 decreases expression
increases expression
multiple interactions		 EXP
ISO		 Cyclophosphamide results in decreased expression of IL4 mRNA; Cyclophosphamide results in decreased expression of IL4 protein
Cyclophosphamide results in increased expression of IL4 mRNA; Cyclophosphamide results in increased expression of IL4 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL4 protein]; ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of IL4 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL4 protein]		 CTD PMID:11006010 PMID:11014644 PMID:11948286 PMID:18848347 PMID:22842586 More... NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Il5 interleukin 5 increases expression EXP
ISO		 Cyclophosphamide results in increased expression of IL5 mRNA; Cyclophosphamide results in increased expression of IL5 protein CTD PMID:11006010 PMID:18848347 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
decreases secretion
increases secretion		 EXP
ISO		 [Cyclophosphamide co-treated with Dexamethasone] inhibits the reaction [Paraquat results in increased expression of IL6 mRNA]; [Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of IL6 protein; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IL6 protein]; Sizofiran promotes the reaction [Cyclophosphamide results in increased expression of IL6 mRNA]; Sizofiran promotes the reaction [Cyclophosphamide results in increased expression of IL6 protein]
allyl sulfide inhibits the reaction [Cyclophosphamide results in increased secretion of IL6 protein]; chrysin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Cilostazol inhibits the reaction [Cyclophosphamide results in increased expression of IL6 mRNA]; O-1602 compound inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Pentoxifylline inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]
Cyclophosphamide results in increased expression of IL6 mRNA; Cyclophosphamide results in increased expression of IL6 protein		 CTD PMID:10052129 PMID:11948286 PMID:17010015 PMID:18848347 PMID:20126887 More... NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Ilf3 interleukin enhancer binding factor 3 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of ILF3 mRNA CTD PMID:16322899 NCBI chr 9:21,278,964...21,316,659
Ensembl chr 9:21,279,167...21,316,657 		JBrowse link
G Irag2 inositol 1,4,5-triphosphate receptor associated 2 decreases expression EXP Cyclophosphamide results in decreased expression of IRAG2 mRNA CTD PMID:21041162 NCBI chr 6:145,061,357...145,120,655
Ensembl chr 6:145,061,379...145,120,660 		JBrowse link
G Irgm2 immunity-related GTPase family M member 2 increases expression EXP Cyclophosphamide results in increased expression of IRGM2 mRNA CTD PMID:15331540 NCBI chr11:58,105,803...58,113,609
Ensembl chr11:58,090,444...58,113,608 		JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of IRS1 mRNA CTD PMID:16322899 NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,822...82,269,137 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier increases expression ISO Cyclophosphamide results in increased expression of ISG15 mRNA CTD PMID:21527772 NCBI chr 4:156,283,881...156,285,275
Ensembl chr 4:156,283,912...156,285,253 		JBrowse link
G Isl2 insulin related protein 2 (islet 2) decreases expression ISO Cyclophosphamide metabolite results in decreased expression of ISL2 mRNA CTD PMID:24356939 NCBI chr 9:55,445,961...55,454,951
Ensembl chr 9:55,445,956...55,453,464 		JBrowse link
G Itk IL2 inducible T cell kinase decreases expression EXP Cyclophosphamide results in decreased expression of ITK mRNA CTD PMID:21041162 NCBI chr11:46,215,975...46,280,342
Ensembl chr11:46,215,977...46,280,342 		JBrowse link
G Jchain immunoglobulin joining chain decreases expression EXP Cyclophosphamide results in decreased expression of JCHAIN mRNA CTD PMID:15331540 NCBI chr 5:88,667,663...88,675,667
Ensembl chr 5:88,667,668...88,675,750 		JBrowse link
G Kbtbd11 kelch repeat and BTB (POZ) domain containing 11 decreases expression ISO Cyclophosphamide results in decreased expression of KBTBD11 mRNA CTD PMID:17403535 NCBI chr 8:15,059,408...15,083,333
Ensembl chr 8:15,061,025...15,083,333 		JBrowse link
G Kcnq4 potassium voltage-gated channel, subfamily Q, member 4 decreases expression ISO Cyclophosphamide results in decreased expression of KCNQ4 mRNA CTD PMID:20849824 NCBI chr 4:120,553,331...120,605,809
Ensembl chr 4:120,553,335...120,605,809 		JBrowse link
G Kdm1a lysine (K)-specific demethylase 1A multiple interactions
increases expression		 ISO Cyclophosphamide promotes the reaction [KDM1A protein results in decreased methylation of and results in decreased degradation of DNMT1 protein]
Cyclophosphamide results in increased expression of KDM1A protein		 CTD PMID:22007908 NCBI chr 4:136,277,844...136,330,127
Ensembl chr 4:136,277,851...136,330,034 		JBrowse link
G Kdm2a lysine (K)-specific demethylase 2A increases expression ISO Cyclophosphamide results in increased expression of KDM2A mRNA CTD PMID:27281708 NCBI chr19:4,366,172...4,448,749
Ensembl chr19:4,364,447...4,448,313 		JBrowse link
G Kdm4b lysine (K)-specific demethylase 4B multiple interactions ISO KDM4B mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr17:56,632,975...56,710,774
Ensembl chr17:56,633,062...56,709,870 		JBrowse link
G Kdr kinase insert domain protein receptor decreases expression
increases expression		 ISO Cyclophosphamide results in decreased expression of KDR mRNA; Cyclophosphamide results in decreased expression of KDR protein
Cyclophosphamide results in increased expression of KDR mRNA		 CTD PMID:18632792 PMID:19701751 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118 		JBrowse link
G Keap1 kelch-like ECH-associated protein 1 decreases expression
multiple interactions		 ISO Cyclophosphamide results in decreased expression of KEAP1 mRNA
Quercetin inhibits the reaction [Cyclophosphamide results in decreased expression of KEAP1 mRNA]		 CTD PMID:37419146 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657 		JBrowse link
G Kif21b kinesin family member 21B decreases expression ISO Cyclophosphamide metabolite results in decreased expression of KIF21B mRNA CTD PMID:24356939 NCBI chr 1:136,059,128...136,105,739
Ensembl chr 1:136,059,127...136,105,736 		JBrowse link
G Kif3a kinesin family member 3A multiple interactions ISO KIF3A mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr11:53,456,531...53,495,075
Ensembl chr11:53,458,206...53,492,794 		JBrowse link
G Kitl kit ligand affects expression
multiple interactions
increases expression		 EXP Cyclophosphamide affects the expression of KITL mRNA
[Cyclophosphamide co-treated with Sizofiran] results in increased expression of KITL mRNA
Cyclophosphamide results in increased expression of KITL mRNA		 CTD PMID:10052129 PMID:12624490 PMID:12662436 NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278 		JBrowse link
G Klf13 Kruppel-like transcription factor 13 decreases expression EXP Cyclophosphamide results in decreased expression of KLF13 mRNA CTD PMID:21041162 NCBI chr 7:63,536,099...63,588,663
Ensembl chr 7:63,536,099...63,588,663 		JBrowse link
G Klf2 Kruppel-like transcription factor 2 (lung) increases expression EXP Cyclophosphamide results in increased expression of KLF2 mRNA CTD PMID:21041162 NCBI chr 8:73,072,906...73,075,498
Ensembl chr 8:73,072,877...73,075,500 		JBrowse link
G Klf4 Kruppel-like transcription factor 4 (gut) decreases response to substance ISO KLF4 results in decreased susceptibility to Cyclophosphamide CTD PMID:21833590 NCBI chr 4:55,527,137...55,536,984
Ensembl chr 4:55,527,143...55,532,466 		JBrowse link
G Klf5 Kruppel-like transcription factor 5 affects response to substance ISO KLF5 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr14:99,536,127...99,550,848
Ensembl chr14:99,536,127...99,552,472 		JBrowse link
G Klrb1c killer cell lectin-like receptor subfamily B member 1C multiple interactions EXP [Cyclophosphamide co-treated with Sizofiran] results in increased expression of KLRB1C mRNA CTD PMID:10052129 NCBI chr 6:128,755,448...128,765,514
Ensembl chr 6:128,755,448...128,766,178 		JBrowse link
G Krcc1 lysine-rich coiled-coil 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of KRCC1 mRNA CTD PMID:24356939 NCBI chr 6:71,248,661...71,263,809
Ensembl chr 6:71,248,661...71,262,303 		JBrowse link
G Krt8 keratin 8 decreases expression EXP Cyclophosphamide results in decreased expression of KRT8 mRNA CTD PMID:21621594 NCBI chr15:101,905,146...101,912,777
Ensembl chr15:101,905,133...101,912,917 		JBrowse link
G Krt80 keratin 80 increases expression ISO Cyclophosphamide results in increased expression of KRT80 mRNA CTD PMID:21527772 NCBI chr15:101,246,196...101,268,043
Ensembl chr15:101,245,325...101,268,043 		JBrowse link
G Lama5 laminin, alpha 5 multiple interactions
increases expression		 EXP 5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline inhibits the reaction [Cyclophosphamide results in increased expression of LAMA5 mRNA] CTD PMID:30760223 NCBI chr 2:179,818,166...179,867,652
Ensembl chr 2:179,818,166...179,867,652 		JBrowse link
G Lamc2 laminin, gamma 2 increases expression ISO Cyclophosphamide results in increased expression of LAMC2 mRNA CTD PMID:21527772 NCBI chr 1:152,998,502...153,062,193
Ensembl chr 1:152,998,502...153,062,193 		JBrowse link
G Lasp1 LIM and SH3 protein 1 decreases expression ISO Cyclophosphamide results in decreased expression of LASP1 mRNA CTD PMID:27281708 NCBI chr11:97,689,748...97,729,591
Ensembl chr11:97,689,826...97,729,590 		JBrowse link
G Lat linker for activation of T cells decreases expression EXP Cyclophosphamide results in decreased expression of LAT mRNA CTD PMID:21041162 NCBI chr 7:125,962,999...125,968,877
Ensembl chr 7:125,962,996...125,968,742 		JBrowse link
G Lck lymphocyte protein tyrosine kinase decreases expression EXP Cyclophosphamide results in decreased expression of LCK mRNA CTD PMID:21041162 NCBI chr 4:129,442,142...129,467,415
Ensembl chr 4:129,442,137...129,467,434 		JBrowse link
G Lcn2 lipocalin 2 increases expression
multiple interactions		 EXP
ISO		 Cyclophosphamide results in increased expression of LCN2 mRNA
[Cyclophosphamide co-treated with Mecamylamine] results in increased expression of LCN2 mRNA		 CTD PMID:15331540 PMID:18433785 PMID:20623750 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264 		JBrowse link
G Ldhb lactate dehydrogenase B affects response to substance ISO LDHB protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 6:142,435,975...142,453,683
Ensembl chr 6:142,435,975...142,453,683 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 decreases expression EXP Cyclophosphamide results in decreased expression of LEF1 mRNA CTD PMID:21041162 NCBI chr 3:130,903,972...131,018,006
Ensembl chr 3:130,904,120...131,018,005 		JBrowse link
G Lgals1 lectin, galactose binding, soluble 1 increases expression ISO Cyclophosphamide results in increased expression of LGALS1 mRNA CTD PMID:17403535 NCBI chr15:78,810,925...78,814,665
Ensembl chr15:78,810,925...78,814,665 		JBrowse link
G Lgals7 lectin, galactose binding, soluble 7 increases expression ISO Cyclophosphamide results in increased expression of LGALS7 mRNA CTD PMID:21527772 NCBI chr 7:28,563,258...28,565,711
Ensembl chr 7:28,563,278...28,565,709 		JBrowse link
G Lhb luteinizing hormone beta decreases secretion
multiple interactions
increases expression		 ISO Cyclophosphamide results in decreased secretion of LHB protein
Cilostazol inhibits the reaction [Cyclophosphamide results in increased expression of LHB protein]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in decreased secretion of LHB protein]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased secretion of LHB protein]		 CTD PMID:25446862 PMID:32197949 PMID:32456565 NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321 		JBrowse link
G Lhx2 LIM homeobox protein 2 decreases expression ISO Cyclophosphamide results in decreased expression of LHX2 mRNA CTD PMID:27281708 NCBI chr 2:38,229,282...38,259,747
Ensembl chr 2:38,229,293...38,259,745 		JBrowse link
G Limd1 LIM domains containing 1 increases expression ISO Cyclophosphamide results in increased expression of LIMD1 mRNA CTD PMID:27281708 NCBI chr 9:123,306,790...123,350,617
Ensembl chr 9:123,307,771...123,350,617 		JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 increases expression ISO Cyclophosphamide results in increased expression of LMCD1 mRNA CTD PMID:23558518 NCBI chr 6:112,250,747...112,307,384
Ensembl chr 6:112,250,719...112,307,386 		JBrowse link
G Lmnb1 lamin B1 multiple interactions ISO [Cladribine co-treated with Cyclophosphamide co-treated with Mitoxantrone] results in decreased expression of LMNB1 protein; [Cladribine co-treated with Cyclophosphamide] results in decreased expression of LMNB1 protein CTD PMID:15582267 NCBI chr18:56,840,885...56,886,496
Ensembl chr18:56,840,885...56,886,496 		JBrowse link
G Lonrf2 LON peptidase N-terminal domain and ring finger 2 increases expression ISO Cyclophosphamide results in increased expression of LONRF2 mRNA CTD PMID:27281708 NCBI chr 1:38,832,750...38,875,768
Ensembl chr 1:38,832,726...38,875,792 		JBrowse link
G Lsg1 large 60S subunit nuclear export GTPase 1 decreases expression ISO Cyclophosphamide results in decreased expression of LSG1 mRNA CTD PMID:20849824 NCBI chr16:30,380,187...30,406,430
Ensembl chr16:30,379,312...30,406,410 		JBrowse link
G Ltbr lymphotoxin B receptor increases expression EXP Cyclophosphamide results in increased expression of LTBR mRNA CTD PMID:21041162 NCBI chr 6:125,283,534...125,291,026
Ensembl chr 6:125,283,534...125,290,848 		JBrowse link
G Ltf lactotransferrin decreases expression EXP Cyclophosphamide results in decreased expression of LTF mRNA CTD PMID:21621594 NCBI chr 9:110,848,360...110,871,834
Ensembl chr 9:110,848,339...110,871,835 		JBrowse link
G Ly6a lymphocyte antigen 6 family member A increases expression EXP Cyclophosphamide results in increased expression of LY6A mRNA CTD PMID:15331540 PMID:21041162 NCBI chr15:74,866,726...74,869,880
Ensembl chr15:74,866,726...74,869,880 		JBrowse link
G Ly6c1 lymphocyte antigen 6 family member C1 increases expression EXP Cyclophosphamide results in increased expression of LY6C1 mRNA CTD PMID:21041162 NCBI chr15:74,915,867...74,920,690
Ensembl chr15:74,915,867...74,920,679 		JBrowse link
G Maged1 MAGE family member D1 affects response to substance ISO MAGED1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr  X:93,579,080...93,585,631
Ensembl chr  X:93,579,080...93,585,749 		JBrowse link
G Man2b2 mannosidase 2, alpha B2 decreases expression ISO Cyclophosphamide results in decreased expression of MAN2B2 mRNA CTD PMID:27281708 NCBI chr 5:36,963,913...36,987,973
Ensembl chr 5:36,964,265...36,987,997 		JBrowse link
G Maoa monoamine oxidase A increases expression ISO Cyclophosphamide results in increased expression of MAOA mRNA CTD PMID:17403535 NCBI chr  X:16,485,937...16,554,051
Ensembl chr  X:16,485,937...16,554,057 		JBrowse link
G Map3k12 mitogen-activated protein kinase kinase kinase 12 affects expression ISO Cyclophosphamide affects the expression of MAP3K12 mRNA CTD PMID:18246545 NCBI chr15:102,406,079...102,425,311
Ensembl chr15:102,406,081...102,425,499 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 increases phosphorylation
increases expression
multiple interactions		 EXP
ISO		 Cyclophosphamide results in increased phosphorylation of MAPK1 protein
Cyclophosphamide results in increased expression of MAPK1 mRNA; Cyclophosphamide results in increased expression of MAPK1 protein modified form
Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK1 protein; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]		 CTD PMID:11599041 PMID:15733095 PMID:17110531 PMID:17409261 PMID:19638304 More... NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk14 mitogen-activated protein kinase 14 multiple interactions
affects expression
decreases expression
increases expression		 ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of MAPK14 mRNA
Cyclophosphamide affects the expression of MAPK14 mRNA
Cyclophosphamide results in decreased expression of MAPK14 mRNA
Cyclophosphamide results in increased expression of MAPK14 protein
chrysin inhibits the reaction [Cyclophosphamide results in increased expression of MAPK14 protein]		 CTD PMID:16322899 PMID:18246545 PMID:37263553 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases expression
increases phosphorylation
multiple interactions		 ISO
EXP		 Cyclophosphamide results in increased expression of MAPK3 protein modified form
Cyclophosphamide results in increased phosphorylation of MAPK3 protein
Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK3 protein; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]		 CTD PMID:15733095 PMID:17110531 PMID:17409261 PMID:19638304 PMID:19696094 More... NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 multiple interactions ISO Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK7 protein CTD PMID:17110531 NCBI chr11:61,379,638...61,385,101
Ensembl chr11:61,379,638...61,385,232 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions		 EXP
ISO		 Cyclophosphamide results in increased phosphorylation of MAPK8 protein
GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]; GSTP2 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]; Mesna inhibits the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]; Mesna inhibits the reaction [GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]]; Mesna inhibits the reaction [GSTP2 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]]
Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein]		 CTD PMID:19696094 PMID:19996110 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK9 protein; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK9 protein] CTD PMID:19996110 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248 		JBrowse link
G Mapt microtubule-associated protein tau multiple interactions ISO MAPT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr11:104,120,235...104,222,916
Ensembl chr11:104,122,216...104,222,916 		JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 decreases expression ISO Cyclophosphamide results in decreased expression of MARCHF7 mRNA CTD PMID:27281708 NCBI chr 2:60,040,086...60,079,555
Ensembl chr 2:60,040,231...60,081,020 		JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate increases expression ISO Cyclophosphamide results in increased expression of MARCKS mRNA CTD PMID:17403535 NCBI chr10:37,009,239...37,014,922
Ensembl chr10:37,009,371...37,014,916 		JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression EXP Cyclophosphamide results in decreased expression of MCM5 mRNA CTD PMID:21041162 NCBI chr 8:75,836,096...75,855,067
Ensembl chr 8:75,836,197...75,855,067 		JBrowse link
G Mdfic MyoD family inhibitor domain containing decreases expression ISO Cyclophosphamide results in decreased expression of MDFIC mRNA CTD PMID:17403535 NCBI chr 6:15,720,660...15,802,168
Ensembl chr 6:15,720,660...15,802,168 		JBrowse link
G Med13l mediator complex subunit 13-like multiple interactions ISO MED13L mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 5:118,698,363...118,903,503
Ensembl chr 5:118,698,744...118,903,503 		JBrowse link
G Melk maternal embryonic leucine zipper kinase multiple interactions ISO MELK mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 4:44,300,876...44,364,301
Ensembl chr 4:44,300,876...44,364,675 		JBrowse link
G Metrn meteorin, glial cell differentiation regulator multiple interactions ISO METRN mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr17:26,013,545...26,016,019
Ensembl chr17:26,012,195...26,016,057 		JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing decreases expression EXP Cyclophosphamide results in decreased expression of MFGE8 mRNA CTD PMID:15331540 NCBI chr 7:78,783,516...78,798,808
Ensembl chr 7:78,783,516...78,798,808 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases expression
decreases response to substance		 ISO Cyclophosphamide results in decreased expression of MGMT mRNA
MGMT protein results in decreased susceptibility to Cyclophosphamide		 CTD PMID:15741301 PMID:17403535 NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 decreases expression ISO Cyclophosphamide results in decreased expression of MGST1 mRNA CTD PMID:11906922 NCBI chr 6:138,117,525...138,133,753
Ensembl chr 6:138,117,314...138,133,753 		JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) multiple interactions ISO Cyclophosphamide affects the localization of and affects the expression of MIF protein; Cyclophosphamide promotes the reaction [MIF protein binds to CXCR4 protein] CTD PMID:19066630 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074 		JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 decreases expression EXP Cyclophosphamide results in decreased expression of MKI67 protein CTD PMID:33737021 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090 		JBrowse link
G Mlh1 mutL homolog 1 decreases expression ISO Cyclophosphamide results in decreased expression of MLH1 mRNA CTD PMID:11906922 NCBI chr 9:111,057,296...111,100,854
Ensembl chr 9:111,057,296...111,100,859 		JBrowse link
G Mllt11 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 decreases response to substance ISO MLLT11 protein results in decreased susceptibility to Cyclophosphamide CTD PMID:31587870 NCBI chr 3:95,125,852...95,139,486
Ensembl chr 3:95,126,446...95,139,482 		JBrowse link
G Mmel1 membrane metallo-endopeptidase-like 1 increases expression ISO Cyclophosphamide results in increased expression of MMEL1 mRNA CTD PMID:27281708 NCBI chr 4:154,954,042...154,979,987
Ensembl chr 4:154,954,042...154,979,985 		JBrowse link
G Mmp11 matrix metallopeptidase 11 decreases expression ISO Cyclophosphamide results in decreased expression of MMP11 mRNA CTD PMID:27281708 NCBI chr10:75,759,056...75,768,336
Ensembl chr10:75,759,056...75,772,330 		JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression EXP Cyclophosphamide results in increased expression of MMP3 mRNA CTD PMID:15331540 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975 		JBrowse link
G Mmp8 matrix metallopeptidase 8 increases expression ISO Cyclophosphamide results in increased expression of MMP8 mRNA CTD PMID:27281708 NCBI chr 9:7,558,430...7,568,487
Ensembl chr 9:7,558,457...7,568,486 		JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 affects response to substance ISO MPC2 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 1:165,288,829...165,308,787
Ensembl chr 1:165,288,206...165,308,783 		JBrowse link
G Mpg N-methylpurine-DNA glycosylase affects expression ISO Cyclophosphamide affects the expression of MPG mRNA CTD PMID:11906922 NCBI chr11:32,176,505...32,182,702
Ensembl chr11:32,176,505...32,182,700 		JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity		 ISO Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein]; Hemin inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein]; Rolipram inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein] CTD PMID:10749792 PMID:17979934 PMID:18710439 PMID:25451569 PMID:34748891 More... NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G Mr1 major histocompatibility complex, class I-related increases expression ISO Cyclophosphamide results in increased expression of MR1 mRNA CTD PMID:21527772 NCBI chr 1:155,003,620...155,022,560
Ensembl chr 1:155,003,023...155,022,560 		JBrowse link
G Ms4a3 membrane-spanning 4-domains, subfamily A, member 3 decreases expression ISO Cyclophosphamide results in decreased expression of MS4A3 mRNA CTD PMID:17403535 NCBI chr19:11,606,863...11,618,215
Ensembl chr19:11,606,860...11,618,215 		JBrowse link
G Msh2 mutS homolog 2 decreases expression ISO Cyclophosphamide results in decreased expression of MSH2 mRNA CTD PMID:11056294 PMID:11906922 NCBI chr17:87,979,960...88,031,141
Ensembl chr17:87,979,758...88,031,141 		JBrowse link
G Msh3 mutS homolog 3 decreases expression ISO Cyclophosphamide results in decreased expression of MSH3 mRNA CTD PMID:11906922 NCBI chr13:92,348,387...92,491,515
Ensembl chr13:92,348,380...92,491,511 		JBrowse link
G Mss51 MSS51 mitochondrial translational activator increases expression ISO Cyclophosphamide results in increased expression of MSS51 mRNA CTD PMID:27281708 NCBI chr14:20,532,925...20,546,969
Ensembl chr14:20,532,935...20,546,969 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase decreases expression ISO Cyclophosphamide metabolite results in decreased expression of MTHFD2 mRNA CTD PMID:24356939 NCBI chr 6:83,282,686...83,302,926
Ensembl chr 6:83,282,673...83,302,890 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase decreases expression ISO Cyclophosphamide results in decreased expression of MTR mRNA CTD PMID:27281708 NCBI chr13:12,196,217...12,273,090
Ensembl chr13:12,197,598...12,272,999 		JBrowse link
G Muc13 mucin 13, epithelial transmembrane increases expression EXP Cyclophosphamide results in increased expression of MUC13 mRNA CTD PMID:15331540 NCBI chr16:33,614,407...33,640,299
Ensembl chr16:33,614,407...33,640,304 		JBrowse link
G Mup2 major urinary protein 2 decreases expression EXP Cyclophosphamide results in decreased expression of MUP2 mRNA CTD PMID:21621594 NCBI chr 4:60,135,913...60,139,977
Ensembl chr 4:60,135,932...60,154,289 		JBrowse link
G Mup5 major urinary protein 5 decreases expression EXP Cyclophosphamide results in decreased expression of MUP5 mRNA CTD PMID:21621594 NCBI chr 4:61,749,556...61,753,417
Ensembl chr 4:61,749,556...61,753,470 		JBrowse link
G Mxi1 MAX interactor 1, dimerization protein affects response to substance ISO MXI1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr19:53,298,509...53,361,724
Ensembl chr19:53,298,949...53,364,241 		JBrowse link
G Myh10 myosin, heavy polypeptide 10, non-muscle affects response to substance ISO MYH10 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr11:68,581,228...68,707,451
Ensembl chr11:68,582,385...68,707,458 		JBrowse link
G Naip2 NLR family, apoptosis inhibitory protein 2 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of NAIP mRNA CTD PMID:16322899 NCBI chr13:100,280,571...100,338,630
Ensembl chr13:100,280,571...100,338,600 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression EXP Cyclophosphamide results in increased expression of NAMPT mRNA CTD PMID:21041162 NCBI chr12:32,870,334...32,903,368
Ensembl chr12:32,869,544...32,903,348 		JBrowse link
G Nanos1 nanos C2HC-type zinc finger 1 increases expression ISO Cyclophosphamide metabolite results in increased expression of NANOS1 mRNA CTD PMID:24356939 NCBI chr19:60,744,425...60,748,352
Ensembl chr19:60,744,425...60,748,352 		JBrowse link
G Nasp nuclear autoantigenic sperm protein (histone-binding) increases expression ISO Cyclophosphamide results in increased expression of NASP mRNA CTD PMID:16141653 NCBI chr 4:116,458,249...116,488,894
Ensembl chr 4:116,458,249...116,485,138 		JBrowse link
G Ncoa7 nuclear receptor coactivator 7 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of NCOA7 mRNA CTD PMID:24356939 NCBI chr10:30,521,578...30,683,401
Ensembl chr10:30,504,995...30,679,322 		JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 decreases expression EXP Cyclophosphamide results in decreased expression of NDUFS2 mRNA CTD PMID:15331540 NCBI chr 1:171,062,426...171,078,956
Ensembl chr 1:171,062,422...171,078,957 		JBrowse link
G Neto2 neuropilin (NRP) and tolloid (TLL)-like 2 increases expression ISO Cyclophosphamide results in increased expression of NETO2 mRNA CTD PMID:21527772 NCBI chr 8:86,363,347...86,428,011
Ensembl chr 8:86,363,217...86,427,553 		JBrowse link
G Nfatc3 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 decreases expression EXP Cyclophosphamide results in decreased expression of NFATC3 mRNA CTD PMID:21041162 NCBI chr 8:106,785,450...106,857,169
Ensembl chr 8:106,785,472...106,857,169 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions
decreases expression
increases expression
increases response to substance		 ISO
EXP		 [astaxanthine co-treated with Cyclophosphamide] results in increased expression of NFE2L2 protein; Cilostazol inhibits the reaction [Cyclophosphamide results in decreased expression of NFE2L2 mRNA]; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of NFE2L2 protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of NFE2L2 mRNA]
Cyclophosphamide results in decreased expression of NFE2L2 mRNA; Cyclophosphamide results in decreased expression of NFE2L2 protein
Cyclophosphamide results in increased expression of NFE2L2 mRNA; Cyclophosphamide results in increased expression of NFE2L2 protein
Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of CAT protein]; Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of GCLC protein]; Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of NQO1 protein]; NFE2L2 gene mutant form inhibits the reaction [Cyclophosphamide results in increased expression of NQO1 mRNA]; NFE2L2 gene mutant form promotes the reaction [Cyclophosphamide results in decreased expression of CAT protein]; NFE2L2 gene mutant form promotes the reaction [Cyclophosphamide results in decreased expression of NQO1 protein]
NFE2L2 gene mutant form results in increased susceptibility to Cyclophosphamide		 CTD PMID:20038455 PMID:20433640 PMID:27633142 PMID:32456565 PMID:37419146 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nfe2l3 nuclear factor, erythroid derived 2, like 3 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of NFE2L3 mRNA CTD PMID:24356939 NCBI chr 6:51,409,649...51,435,752
Ensembl chr 6:51,409,650...51,435,748 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions
increases phosphorylation		 EXP ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased phosphorylation of NFKBIA protein] CTD PMID:30506662 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Nfkbiz nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta increases expression EXP Cyclophosphamide results in increased expression of NFKBIZ mRNA CTD PMID:15331540 NCBI chr16:55,631,740...55,659,018
Ensembl chr16:55,631,738...55,659,262 		JBrowse link
G Ngf nerve growth factor multiple interactions
increases expression
decreases expression		 EXP
ISO		 3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazoleacetic acid methyl ester inhibits the reaction [Cyclophosphamide results in increased expression of NGF protein]; Cyclophosphamide promotes the reaction [NGF results in increased expression of VEGFA mRNA]; VIP protein affects the reaction [Cyclophosphamide results in increased expression of NGF protein]
Cyclophosphamide results in decreased expression of NGF protein
Cyclophosphamide results in increased expression of NGF mRNA; Cyclophosphamide results in increased expression of NGF protein
NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of AKT1 protein]; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein]; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK9 protein]; O-1602 compound inhibits the reaction [Cyclophosphamide results in increased expression of NGF protein]; rofecoxib inhibits the reaction [Cyclophosphamide results in increased expression of NGF protein]		 CTD PMID:10683293 PMID:16879691 PMID:18299998 PMID:18632792 PMID:19996110 More... NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329 		JBrowse link
G Ngfr nerve growth factor receptor (TNFR superfamily, member 16) increases expression ISO Cyclophosphamide results in increased expression of NGFR mRNA; Cyclophosphamide results in increased expression of NGFR protein CTD PMID:8817519 PMID:18189308 PMID:18842820 NCBI chr11:95,459,644...95,478,524
Ensembl chr11:95,459,644...95,478,561 		JBrowse link
G Nid1 nidogen 1 affects response to substance ISO NID1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr13:13,612,252...13,686,849
Ensembl chr13:13,612,136...13,686,854 		JBrowse link
G Nkain1 Na+/K+ transporting ATPase interacting 1 multiple interactions ISO NKAIN1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 4:130,297,176...130,341,115
Ensembl chr 4:130,297,197...130,339,644 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression		 ISO Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of NLRP3 protein]]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of NLRP3 protein] CTD PMID:35762198 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782 		JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 increases expression ISO Cyclophosphamide results in increased expression of NME1 mRNA CTD PMID:11599041 NCBI chr11:93,849,751...93,859,341
Ensembl chr11:93,847,805...93,859,347 		JBrowse link
G Nos1 nitric oxide synthase 1, neuronal decreases expression
multiple interactions
increases expression		 ISO Cyclophosphamide results in decreased expression of NOS1 protein
allyl sulfide inhibits the reaction [Cyclophosphamide results in decreased expression of NOS1 protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of NOS1 protein]		 CTD PMID:31779506 PMID:35906875 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible increases expression
multiple interactions
increases activity
decreases expression		 EXP
ISO		 Cyclophosphamide results in increased expression of NOS2 mRNA; Cyclophosphamide results in increased expression of NOS2 protein
allyl sulfide inhibits the reaction [Cyclophosphamide results in decreased expression of NOS2 protein]; Bilirubin inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 mRNA]; Bilirubin inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; chrysin inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; ginkgolide B inhibits the reaction [Cyclophosphamide results in increased activity of NOS2 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Cyclophosphamide results in increased activity of NOS2 protein]; pimagedine inhibits the reaction [Cyclophosphamide results in increased activity of NOS2 protein]; rofecoxib inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; Rolipram inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 mRNA]; Rolipram inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]		 CTD PMID:9006340 PMID:10607705 PMID:11046124 PMID:15821589 PMID:16879691 More... NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell decreases activity
increases expression
multiple interactions
decreases expression		 ISO Cyclophosphamide results in decreased activity of NOS3 protein
Cyclophosphamide results in increased expression of NOS3 protein
Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in decreased expression of NOS3 protein]]; Simvastatin inhibits the reaction [Cyclophosphamide results in decreased expression of NOS3 protein]		 CTD PMID:9006340 PMID:16125470 PMID:35762198 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Nppb natriuretic peptide type B increases expression ISO Cyclophosphamide results in increased expression of NPPB protein CTD PMID:17562616 PMID:18548196 PMID:18999883 NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662 		JBrowse link
G Nprl2 NPR2 like, GATOR1 complex subunit decreases expression ISO Cyclophosphamide results in decreased expression of NPRL2 mRNA CTD PMID:20849824 NCBI chr 9:107,419,405...107,422,905
Ensembl chr 9:107,419,425...107,422,905 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 decreases expression
multiple interactions
increases expression		 ISO
EXP		 Cyclophosphamide results in decreased expression of NQO1 mRNA; Cyclophosphamide results in decreased expression of NQO1 protein
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of NQO1 protein; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of NQO1 protein]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in decreased expression of NQO1 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased expression of NQO1 protein]
Cyclophosphamide results in increased expression of NQO1 mRNA
Cyclophosphamide results in increased expression of NQO1 protein
Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of NQO1 protein]; NFE2L2 gene mutant form inhibits the reaction [Cyclophosphamide results in increased expression of NQO1 mRNA]; NFE2L2 gene mutant form promotes the reaction [Cyclophosphamide results in decreased expression of NQO1 protein]		 CTD PMID:11906922 PMID:20038455 PMID:20433640 PMID:21041162 PMID:27633142 More... NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression ISO Cyclophosphamide results in decreased expression of NR1H4 mRNA CTD PMID:28391356 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions		 ISO Cyclophosphamide results in increased activity of NR1I2 protein
[Cyclophosphamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; [Cyclophosphamide results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; Cyclophosphamide binds to and results in increased activity of NR1I2 protein; NR1I2 protein promotes the reaction [Cyclophosphamide results in increased expression of ABCB1 protein]		 CTD PMID:17041008 PMID:18839173 PMID:20041327 NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO [Cyclophosphamide results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA CTD PMID:17041008 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270 		JBrowse link
G Nr2c2 nuclear receptor subfamily 2, group C, member 2 increases expression ISO Cyclophosphamide results in increased expression of NR2C2 mRNA CTD PMID:27281708 NCBI chr 6:92,068,426...92,150,039
Ensembl chr 6:92,068,371...92,151,275 		JBrowse link
G Nrap nebulin-related anchoring protein increases expression ISO Cyclophosphamide results in increased expression of NRAP mRNA CTD PMID:27281708 NCBI chr19:56,308,473...56,378,466
Ensembl chr19:56,308,467...56,378,469 		JBrowse link
G Nrdc nardilysin convertase decreases expression ISO Cyclophosphamide results in decreased expression of NRDC mRNA CTD PMID:27281708 NCBI chr 4:108,857,852...108,918,974
Ensembl chr 4:108,857,852...108,918,974 		JBrowse link
G Nrg1 neuregulin 1 increases expression ISO Cyclophosphamide results in increased expression of NRG1 mRNA CTD PMID:21527772 NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825
Ensembl chr 8:32,304,579...33,374,825 		JBrowse link
G Nrp1 neuropilin 1 decreases expression
increases expression		 EXP
ISO		 Cyclophosphamide results in decreased expression of NRP1 mRNA
Cyclophosphamide results in increased expression of NRP1 mRNA		 CTD PMID:15331540 PMID:18632792 NCBI chr 8:129,085,553...129,231,957
Ensembl chr 8:129,085,085...129,229,844 		JBrowse link
G Nrp2 neuropilin 2 increases expression ISO Cyclophosphamide results in increased expression of NRP2 mRNA CTD PMID:18632792 NCBI chr 1:62,742,476...62,857,851
Ensembl chr 1:62,742,444...62,857,854 		JBrowse link
G Nt5c2 5'-nucleotidase, cytosolic II increases expression ISO Cyclophosphamide results in increased expression of NT5C2 mRNA CTD PMID:20849824 NCBI chr19:46,873,829...47,003,613
Ensembl chr19:46,871,756...47,003,592 		JBrowse link
G Ntf3 neurotrophin 3 increases expression ISO Cyclophosphamide results in increased expression of NTF3 mRNA CTD PMID:10683293 NCBI chr 6:126,078,375...126,143,703
Ensembl chr 6:126,078,375...126,143,873 		JBrowse link
G Ntf5 neurotrophin 5 increases expression ISO Cyclophosphamide results in increased expression of NTF4 mRNA CTD PMID:10683293 NCBI chr 7:45,063,119...45,066,603
Ensembl chr 7:45,063,119...45,066,603 		JBrowse link
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 multiple interactions ISO Cyclophosphamide results in increased phosphorylation of and results in increased expression of NTRK1 protein CTD PMID:12412144 NCBI chr 3:87,685,551...87,702,549
Ensembl chr 3:87,685,551...87,702,469 		JBrowse link
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 multiple interactions ISO Cyclophosphamide results in increased phosphorylation of and results in increased expression of NTRK2 protein CTD PMID:12412144 NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784 		JBrowse link
G Nup42 nucleoporin 42 increases expression ISO Cyclophosphamide results in increased expression of NUP42 mRNA CTD PMID:27281708 NCBI chr 5:24,369,961...24,389,011
Ensembl chr 5:24,369,961...24,389,011 		JBrowse link
G Ocln occludin multiple interactions
decreases expression
increases expression		 EXP
ISO		 Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of OCLN protein]
O-1602 compound inhibits the reaction [Cyclophosphamide results in increased expression of OCLN protein]		 CTD PMID:32151603 PMID:32615180 NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226 		JBrowse link
G Odc1 ornithine decarboxylase, structural 1 increases expression ISO Cyclophosphamide results in increased expression of ODC1 mRNA CTD PMID:11599041 NCBI chr12:17,594,906...17,601,503
Ensembl chr12:17,594,795...17,601,506 		JBrowse link
G Ogg1 8-oxoguanine DNA-glycosylase 1 decreases expression EXP Cyclophosphamide results in decreased expression of OGG1 protein CTD PMID:27032448 NCBI chr 6:113,303,959...113,311,149
Ensembl chr 6:113,303,933...113,312,029 		JBrowse link
G Opn3 opsin 3 affects response to substance ISO OPN3 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 1:175,489,993...175,520,198
Ensembl chr 1:175,489,987...175,520,342 		JBrowse link
G Osm oncostatin M affects expression EXP Cyclophosphamide affects the expression of OSM mRNA CTD PMID:12624490 NCBI chr11:4,186,831...4,191,027
Ensembl chr11:4,186,420...4,191,026 		JBrowse link
G P2rx3 purinergic receptor P2X, ligand-gated ion channel, 3 increases expression
multiple interactions		 ISO Cyclophosphamide results in increased expression of P2RX3 protein
GR 82334 inhibits the reaction [Cyclophosphamide results in increased expression of P2RX3 protein]; Suramin inhibits the reaction [Cyclophosphamide results in increased expression of P2RX3 protein]		 CTD PMID:23666265 NCBI chr 2:84,826,893...84,867,446
Ensembl chr 2:84,828,927...84,867,806 		JBrowse link
G P2ry2 purinergic receptor P2Y, G-protein coupled 2 decreases expression ISO Cyclophosphamide results in decreased expression of P2RY2 mRNA CTD PMID:17403535 NCBI chr 7:100,645,775...100,661,260
Ensembl chr 7:100,645,775...100,662,073 		JBrowse link
G Paip1 polyadenylate binding protein-interacting protein 1 decreases expression ISO Cyclophosphamide results in decreased expression of PAIP1 mRNA CTD PMID:20849824 NCBI chr13:119,564,960...119,596,858
Ensembl chr13:119,565,137...119,594,754 		JBrowse link
G Pakap paralemmin A kinase anchor protein increases expression ISO Cyclophosphamide results in increased expression of PALM2AKAP2 mRNA CTD PMID:17403535 NCBI chr 4:57,434,475...57,896,984
Ensembl chr 4:57,717,657...57,896,984
Ensembl chr 4:57,717,657...57,896,984
Ensembl chr 4:57,717,657...57,896,984 		JBrowse link
G Pard3 par-3 family cell polarity regulator decreases expression ISO Cyclophosphamide results in decreased expression of PARD3 mRNA CTD PMID:20849824 NCBI chr 8:127,790,131...128,338,767
Ensembl chr 8:127,790,643...128,338,767 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions
decreases expression
increases cleavage
increases expression		 ISO [Cladribine co-treated with Cyclophosphamide co-treated with Mitoxantrone] results in decreased expression of PARP1 protein; [Cladribine co-treated with Cyclophosphamide] results in decreased expression of PARP1 protein
Cyclophosphamide results in decreased expression of PARP1 mRNA
Cyclophosphamide results in increased cleavage of PARP1 protein
Cyclophosphamide results in increased expression of PARP1 mRNA; Cyclophosphamide results in increased expression of PARP1 protein
chrysin inhibits the reaction [Cyclophosphamide results in increased expression of PARP1 protein]		 CTD PMID:11599041 PMID:11723234 PMID:11906922 PMID:15582267 PMID:17898787 More... NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G Pcna proliferating cell nuclear antigen affects expression
increases expression
decreases expression
multiple interactions		 ISO
EXP		 Cyclophosphamide affects the expression of PCNA mRNA
Cyclophosphamide results in increased expression of PCNA mRNA
Cyclophosphamide results in decreased expression of PCNA protein
Cyclophosphamide results in decreased expression of PCNA mRNA
coenzyme Q10 inhibits the reaction [Cyclophosphamide results in decreased expression of PCNA mRNA]		 CTD PMID:11056294 PMID:18246545 PMID:19701751 PMID:21041162 PMID:31557371 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234 		JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 decreases expression EXP Cyclophosphamide results in decreased expression of PCSK2 mRNA CTD PMID:15331540 NCBI chr 2:143,388,053...143,658,204
Ensembl chr 2:143,388,076...143,658,205 		JBrowse link
G Pdcd4 programmed cell death 4 decreases expression ISO Cyclophosphamide results in decreased expression of PDCD4 mRNA CTD PMID:21873647 NCBI chr19:53,880,662...53,926,024
Ensembl chr19:53,880,662...53,918,291 		JBrowse link
G Pdia3 protein disulfide isomerase associated 3 decreases expression ISO Cyclophosphamide results in decreased expression of PDIA3 mRNA CTD PMID:11906922 NCBI chr 2:121,244,383...121,269,168
Ensembl chr 2:121,244,256...121,269,168 		JBrowse link
G Pdia4 protein disulfide isomerase associated 4 increases expression ISO Cyclophosphamide results in increased expression of PDIA4 mRNA CTD PMID:11599041 NCBI chr 6:47,773,075...47,790,446
Ensembl chr 6:47,773,075...47,790,364 		JBrowse link
G Peli1 pellino 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of PELI1 mRNA CTD PMID:24356939 NCBI chr11:21,041,283...21,100,327
Ensembl chr11:21,041,291...21,100,323 		JBrowse link
G Per1 period circadian clock 1 multiple interactions
decreases expression		 EXP 5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline inhibits the reaction [Cyclophosphamide results in decreased expression of PER1 mRNA] CTD PMID:30760223 NCBI chr11:68,985,934...69,000,791
Ensembl chr11:68,986,043...69,000,786 		JBrowse link
G Phlda2 pleckstrin homology like domain, family A, member 2 increases expression ISO Cyclophosphamide results in increased expression of PHLDA2 mRNA CTD PMID:17403535 NCBI chr 7:143,055,282...143,056,882
Ensembl chr 7:143,055,282...143,056,887 		JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A increases mutagenesis ISO Cyclophosphamide results in increased mutagenesis of PIGA CTD PMID:22923490 NCBI chr  X:163,202,814...163,216,912
Ensembl chr  X:163,202,783...163,216,912 		JBrowse link
G Pigr polymeric immunoglobulin receptor increases expression EXP Cyclophosphamide results in increased expression of PIGR mRNA CTD PMID:15331540 NCBI chr 1:130,754,421...130,779,986
Ensembl chr 1:130,754,421...130,779,986 		JBrowse link
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) increases expression EXP Cyclophosphamide results in increased expression of PLA2G4A mRNA CTD PMID:21041162 NCBI chr 1:149,705,369...149,837,041
Ensembl chr 1:149,705,369...149,837,041 		JBrowse link
G Plau plasminogen activator, urokinase increases expression ISO Cyclophosphamide results in increased expression of PLAU mRNA CTD PMID:21527772 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453 		JBrowse link
G Plod1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of PLOD1 mRNA CTD PMID:16322899 NCBI chr 4:147,994,210...148,021,233
Ensembl chr 4:147,994,210...148,021,224 		JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of PLOD3 mRNA CTD PMID:16322899 NCBI chr 5:137,015,873...137,025,500
Ensembl chr 5:137,015,873...137,025,502 		JBrowse link
G Pms1 PMS1 homolog 1, mismatch repair system component increases expression ISO Cyclophosphamide results in increased expression of PMS1 mRNA CTD PMID:11056294 NCBI chr 1:53,225,794...53,336,190
Ensembl chr 1:53,228,346...53,336,177 		JBrowse link
G Pms2 PMS1 homolog2, mismatch repair system component decreases expression ISO Cyclophosphamide results in decreased expression of PMS2 mRNA CTD PMID:11056294 NCBI chr 5:143,846,379...143,922,538
Ensembl chr 5:143,846,782...143,870,786
Ensembl chr 5:143,846,782...143,870,786 		JBrowse link
G Polm polymerase (DNA directed), mu increases expression ISO Cyclophosphamide results in increased expression of POLM mRNA CTD PMID:20849824 NCBI chr11:5,777,860...5,788,831
Ensembl chr11:5,777,860...5,788,016 		JBrowse link
G Pomc pro-opiomelanocortin-alpha increases expression ISO Cyclophosphamide results in increased expression of POMC protein CTD PMID:15276878 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642 		JBrowse link
G Pon1 paraoxonase 1 increases activity ISO Cyclophosphamide results in increased activity of PON1 protein CTD PMID:17874068 NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946 		JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions
increases expression		 ISO POR promotes the reaction [CYP2B6 results in increased susceptibility to Cyclophosphamide]; POR promotes the reaction [CYP2C18 results in increased susceptibility to Cyclophosphamide]; POR protein promotes the reaction [CYP2B6 protein results in increased susceptibility to Cyclophosphamide]
Cyclophosphamide results in increased expression of POR mRNA		 CTD PMID:9766669 PMID:10919648 PMID:11599041 NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180 		JBrowse link
G Postn periostin, osteoblast specific factor decreases expression EXP Cyclophosphamide results in decreased expression of POSTN mRNA CTD PMID:15331540 NCBI chr 3:54,266,688...54,298,462
Ensembl chr 3:54,268,530...54,298,458 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression
multiple interactions		 EXP Cyclophosphamide results in decreased expression of PPARA protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of PPARA protein]		 CTD PMID:29753871 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma decreases expression
multiple interactions
increases expression		 ISO Cyclophosphamide results in decreased expression of PPARG mRNA
Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of PPARG mRNA]
Cyclophosphamide results in increased expression of PPARG mRNA		 CTD PMID:25446862 PMID:27281708 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Prdm13 PR domain containing 13 affects expression ISO Cyclophosphamide affects the expression of PRDM13 mRNA CTD PMID:27281708 NCBI chr 4:21,675,865...21,685,963
Ensembl chr 4:21,677,480...21,685,963 		JBrowse link
G Prkcg protein kinase C, gamma decreases expression ISO Cyclophosphamide results in decreased expression of PRKCG mRNA CTD PMID:27281708 NCBI chr 7:3,352,038...3,379,615
Ensembl chr 7:3,337,704...3,379,615 		JBrowse link
G Prlr prolactin receptor decreases expression EXP Cyclophosphamide results in decreased expression of PRLR mRNA CTD PMID:15331540 NCBI chr15:10,177,324...10,349,276
Ensembl chr15:10,177,324...10,349,266 		JBrowse link
G Procr protein C receptor, endothelial increases expression ISO Cyclophosphamide results in increased expression of PROCR mRNA CTD PMID:21527772 NCBI chr 2:155,592,159...155,597,391
Ensembl chr 2:155,593,037...155,597,391 		JBrowse link
G Prtn3 proteinase 3 decreases expression ISO Cyclophosphamide results in decreased expression of PRTN3 mRNA CTD PMID:17403535 NCBI chr10:79,715,499...79,719,008
Ensembl chr10:79,710,310...79,719,008 		JBrowse link
G Psma5 proteasome subunit alpha 5 increases expression ISO Cyclophosphamide results in increased expression of PSMA5 protein CTD PMID:17475930 NCBI chr 3:108,164,242...108,187,268
Ensembl chr 3:108,164,242...108,187,290 		JBrowse link
G Ptcra pre T cell antigen receptor alpha decreases expression EXP Cyclophosphamide results in decreased expression of PTCRA mRNA CTD PMID:21041162 NCBI chr17:47,066,589...47,074,659
Ensembl chr17:47,066,589...47,074,638 		JBrowse link
G Ptger1 prostaglandin E receptor 1 (subtype EP1) decreases expression ISO Cyclophosphamide results in decreased expression of PTGER1 protein CTD PMID:20346049 NCBI chr 8:84,393,171...84,399,385
Ensembl chr 8:84,393,307...84,399,382 		JBrowse link
G Ptger4 prostaglandin E receptor 4 (subtype EP4) multiple interactions
increases expression		 ISO Botulinum Toxins, Type A inhibits the reaction [Cyclophosphamide results in increased expression of PTGER4 protein] CTD PMID:18514386 PMID:20346049 NCBI chr15:5,262,880...5,273,668
Ensembl chr15:5,236,142...5,273,668 		JBrowse link
G Ptges3 prostaglandin E synthase 3 increases expression ISO Cyclophosphamide results in increased expression of PTGES3 mRNA CTD PMID:11599041 NCBI chr10:127,894,851...127,913,123
Ensembl chr10:127,894,823...127,913,141 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 increases expression EXP Cyclophosphamide results in increased expression of PTGS1 mRNA CTD PMID:21041162 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 affects response to substance
multiple interactions
increases expression		 ISO
EXP		 PTGS2 protein affects the susceptibility to Cyclophosphamide
Botulinum Toxins, Type A inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]; parthenolide inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 mRNA]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]
Cyclophosphamide results in increased expression of PTGS2 mRNA; Cyclophosphamide results in increased expression of PTGS2 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]		 CTD PMID:12388444 PMID:15331540 PMID:16217747 PMID:17537839 PMID:18514386 More... NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4a1 increases expression EXP Cyclophosphamide results in increased expression of PTP4A1 mRNA CTD PMID:15331540 NCBI chr 1:30,979,384...30,988,838
Ensembl chr 1:30,979,383...30,988,390
Ensembl chr 1:30,979,383...30,988,390 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C decreases expression EXP Cyclophosphamide results in decreased expression of PTPRC mRNA CTD PMID:21041162 NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Pura purine rich element binding protein A increases expression ISO Cyclophosphamide results in increased expression of PURA mRNA CTD PMID:11599041 NCBI chr18:36,413,614...36,434,575
Ensembl chr18:36,414,150...36,425,588 		JBrowse link
G Rad50 RAD50 double strand break repair protein increases expression ISO Cyclophosphamide results in increased expression of RAD50 mRNA CTD PMID:11056294 NCBI chr11:53,540,346...53,598,146
Ensembl chr11:53,540,346...53,598,146 		JBrowse link
G Rad51 RAD51 recombinase decreases expression
increases expression		 EXP
ISO		 Cyclophosphamide results in decreased expression of RAD51 mRNA
Cyclophosphamide results in increased expression of RAD51 mRNA		 CTD PMID:11599041 PMID:21041162 NCBI chr 2:118,943,295...118,966,554
Ensembl chr 2:118,943,274...118,977,926 		JBrowse link
G Rad54l RAD54 like (S. cerevisiae) decreases expression ISO Cyclophosphamide results in decreased expression of RAD54L mRNA CTD PMID:11056294 NCBI chr 4:115,951,458...115,980,875
Ensembl chr 4:115,951,461...115,980,887 		JBrowse link
G Rag1 recombination activating 1 decreases expression EXP Cyclophosphamide results in decreased expression of RAG1 mRNA CTD PMID:21041162 NCBI chr 2:101,468,597...101,479,877
Ensembl chr 2:101,468,627...101,479,846 		JBrowse link
G Ramp1 receptor (calcitonin) activity modifying protein 1 increases expression
multiple interactions		 ISO Cyclophosphamide results in increased expression of RAMP1 mRNA
RAMP1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]		 CTD PMID:16896004 PMID:17403535 NCBI chr 1:91,107,544...91,152,918
Ensembl chr 1:91,107,544...91,152,918 		JBrowse link
G Rapsn receptor-associated protein of the synapse increases expression ISO Cyclophosphamide results in increased expression of RAPSN mRNA CTD PMID:27281708 NCBI chr 2:90,864,594...90,876,074
Ensembl chr 2:90,865,965...90,876,074 		JBrowse link
G Rara retinoic acid receptor, alpha increases expression ISO Cyclophosphamide results in increased expression of RARA mRNA CTD PMID:16141653 NCBI chr11:98,818,626...98,865,768
Ensembl chr11:98,818,644...98,865,768 		JBrowse link
G Rarg retinoic acid receptor, gamma decreases expression ISO Cyclophosphamide results in decreased expression of RARG mRNA CTD PMID:27281708 NCBI chr15:102,143,373...102,165,891
Ensembl chr15:102,143,373...102,165,952 		JBrowse link
G Rbpms RNA binding protein gene with multiple splicing increases expression ISO Cyclophosphamide results in increased expression of RBPMS mRNA CTD PMID:17403535 NCBI chr 8:34,272,671...34,419,925
Ensembl chr 8:34,272,671...34,419,891 		JBrowse link
G Rc3h1 RING CCCH (C3H) domains 1 decreases expression ISO Cyclophosphamide results in decreased expression of RC3H1 mRNA CTD PMID:27281708 NCBI chr 1:160,733,981...160,802,546
Ensembl chr 1:160,733,988...160,802,548 		JBrowse link
G Rc3h2 ring finger and CCCH-type zinc finger domains 2 decreases expression ISO Cyclophosphamide results in decreased expression of RC3H2 mRNA CTD PMID:27281708 NCBI chr 2:37,260,078...37,313,007
Ensembl chr 2:37,260,081...37,312,915 		JBrowse link
G Reg3b regenerating islet-derived 3 beta increases expression EXP
ISO		 Cyclophosphamide results in increased expression of REG3A mRNA; Cyclophosphamide results in increased expression of REG3B mRNA
Cyclophosphamide results in increased expression of REG3B protein		 CTD PMID:15331540 PMID:18295254 NCBI chr 6:78,347,868...78,350,449
Ensembl chr 6:78,347,640...78,350,449 		JBrowse link
G Reg3g regenerating islet-derived 3 gamma increases expression EXP
ISO		 Cyclophosphamide results in increased expression of REG3G mRNA
Cyclophosphamide results in increased expression of REG3G protein		 CTD PMID:15331540 PMID:18295254 NCBI chr 6:78,443,252...78,445,857
Ensembl chr 6:78,443,252...78,445,855 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) increases expression
multiple interactions
increases activity
increases phosphorylation		 ISO
EXP		 Cyclophosphamide results in increased expression of RELA mRNA; Cyclophosphamide results in increased expression of RELA protein; Cyclophosphamide results in increased expression of RELA protein modified form
Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of RELA protein]; Melatonin inhibits the reaction [Cyclophosphamide results in increased expression of RELA protein]; parthenolide inhibits the reaction [Cyclophosphamide results in increased expression of RELA protein modified form]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased activity of RELA protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of RELA mRNA]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased phosphorylation of RELA protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of RELA protein]
Cyclophosphamide results in increased localization of and results in increased activity of RELA protein; Dexamethasone inhibits the reaction [Cyclophosphamide results in increased localization of and results in increased activity of RELA protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased phosphorylation of RELA protein]		 CTD PMID:19303104 PMID:20433640 PMID:22099998 PMID:25451569 PMID:30506662 More... NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Rev1 REV1, DNA directed polymerase decreases response to substance EXP REV1 protein results in decreased susceptibility to Cyclophosphamide CTD PMID:21068378 NCBI chr 1:38,091,867...38,169,191
Ensembl chr 1:38,091,867...38,168,882 		JBrowse link
G Ring1 ring finger protein 1 decreases expression ISO Cyclophosphamide results in decreased expression of RING1 mRNA CTD PMID:27281708 NCBI chr17:34,239,766...34,243,654
Ensembl chr17:34,239,766...34,243,654 		JBrowse link
G Ripply3 ripply transcriptional repressor 3 increases expression ISO Cyclophosphamide results in increased expression of RIPPLY3 mRNA CTD PMID:21527772 NCBI chr16:94,129,281...94,137,794
Ensembl chr16:94,129,279...94,137,794 		JBrowse link
G Rnd1 Rho family GTPase 1 increases expression ISO Cyclophosphamide results in increased expression of RND1 mRNA CTD PMID:23558518 NCBI chr15:98,567,086...98,575,342
Ensembl chr15:98,561,302...98,575,342 		JBrowse link
G Rnf180 ring finger protein 180 increases expression ISO Cyclophosphamide results in increased expression of RNF180 mRNA CTD PMID:27281708 NCBI chr13:105,267,075...105,431,406
Ensembl chr13:105,266,509...105,431,323 		JBrowse link
G Rnf216 ring finger protein 216 decreases expression ISO Cyclophosphamide results in decreased expression of RNF216 mRNA CTD PMID:27281708 NCBI chr 5:142,976,648...143,098,793
Ensembl chr 5:142,976,648...143,098,749 		JBrowse link
G Rnf44 ring finger protein 44 increases expression ISO Cyclophosphamide results in increased expression of RNF44 mRNA CTD PMID:27281708 NCBI chr13:54,827,212...54,841,889
Ensembl chr13:54,827,212...54,841,720 		JBrowse link
G Rnf5 ring finger protein 5 increases expression ISO Cyclophosphamide results in increased expression of RNF5 mRNA CTD PMID:27281708 NCBI chr17:34,820,073...34,822,535
Ensembl chr17:34,820,065...34,822,664 		JBrowse link
G Rorc RAR-related orphan receptor gamma decreases expression
multiple interactions		 EXP Cyclophosphamide results in decreased expression of RORC protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of RORC protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of RORC protein]		 CTD PMID:32151603 NCBI chr 3:94,280,106...94,305,583
Ensembl chr 3:94,280,101...94,305,583 		JBrowse link
G Rpa1 replication protein A1 decreases expression ISO Cyclophosphamide results in decreased expression of RPA1 mRNA CTD PMID:11906922 NCBI chr11:75,191,085...75,239,478
Ensembl chr11:75,188,992...75,239,150 		JBrowse link
G Rpa2 replication protein A2 decreases expression ISO Cyclophosphamide results in decreased expression of RPA2 mRNA CTD PMID:11906922 NCBI chr 4:132,495,671...132,506,057
Ensembl chr 4:132,495,643...132,506,063 		JBrowse link
G Rps3 ribosomal protein S3 decreases expression ISO Cyclophosphamide results in decreased expression of RPS3 mRNA CTD PMID:11906922 NCBI chr 7:99,127,103...99,132,916
Ensembl chr 7:99,127,103...99,132,945 		JBrowse link
G Rps6ka2 ribosomal protein S6 kinase, polypeptide 2 affects response to substance ISO RPS6KA2 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr17:7,356,384...7,570,714
Ensembl chr17:7,292,942...7,570,726 		JBrowse link
G Rraga Ras-related GTP binding A decreases expression ISO Cyclophosphamide results in decreased expression of RRAGA mRNA CTD PMID:17403535 NCBI chr 4:86,493,910...86,495,522
Ensembl chr 4:86,493,905...86,495,522 		JBrowse link
G Rras2 related RAS viral (r-ras) oncogene 2 increases expression ISO Cyclophosphamide results in increased expression of RRAS2 mRNA CTD PMID:17403535 NCBI chr 7:113,646,017...113,717,016
Ensembl chr 7:113,646,017...113,717,016 		JBrowse link
G Rrm1 ribonucleotide reductase M1 decreases expression EXP Cyclophosphamide results in decreased expression of RRM1 mRNA CTD PMID:21041162 NCBI chr 7:102,090,902...102,118,978
Ensembl chr 7:102,090,902...102,118,978 		JBrowse link
G Rrm2 ribonucleotide reductase M2 multiple interactions ISO RRM2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr12:24,758,253...24,764,145
Ensembl chr12:24,758,240...24,764,145 		JBrowse link
G Rrm2b ribonucleotide reductase M2 B (TP53 inducible) increases expression ISO Cyclophosphamide metabolite results in increased expression of RRM2B mRNA CTD PMID:21704725 NCBI chr15:37,924,196...37,961,562
Ensembl chr15:37,924,196...37,961,562 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 increases expression ISO Cyclophosphamide results in increased expression of RTEL1 protein CTD PMID:17475930 NCBI chr 2:180,961,504...180,998,409
Ensembl chr 2:180,961,532...180,998,409 		JBrowse link
G Runx3 runt related transcription factor 3 decreases expression ISO Cyclophosphamide results in decreased expression of RUNX3 mRNA CTD PMID:20849824 NCBI chr 4:134,847,956...134,905,301
Ensembl chr 4:134,847,963...134,905,301 		JBrowse link
G Saa3 serum amyloid A 3 increases expression EXP Cyclophosphamide results in increased expression of SAA3 mRNA CTD PMID:15331540 NCBI chr 7:46,361,422...46,365,100
Ensembl chr 7:46,361,422...46,365,124 		JBrowse link
G Sall1 spalt like transcription factor 1 affects response to substance ISO SALL1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 8:89,753,867...89,770,790
Ensembl chr 8:89,753,863...89,770,790 		JBrowse link
G Satb1 special AT-rich sequence binding protein 1 decreases expression EXP Cyclophosphamide results in decreased expression of SATB1 mRNA CTD PMID:21041162 NCBI chr17:52,043,215...52,140,318
Ensembl chr17:52,043,215...52,140,318 		JBrowse link
G Scg3 secretogranin III decreases expression EXP Cyclophosphamide results in decreased expression of SCG3 mRNA CTD PMID:15331540 NCBI chr 9:75,550,648...75,591,733
Ensembl chr 9:75,550,471...75,591,338 		JBrowse link
G Scrt1 scratch family zinc finger 1 increases expression ISO Cyclophosphamide results in increased expression of SCRT1 mRNA CTD PMID:27281708 NCBI chr15:76,400,403...76,406,329
Ensembl chr15:76,400,403...76,406,699 		JBrowse link
G Scube2 signal peptide, CUB domain, EGF-like 2 multiple interactions ISO SCUBE2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 7:109,397,897...109,464,886
Ensembl chr 7:109,397,883...109,464,886 		JBrowse link
G Sec23a SEC23 homolog A, COPII coat complex component decreases expression ISO Cyclophosphamide results in decreased expression of SEC23A mRNA CTD PMID:27281708 NCBI chr12:59,005,170...59,058,803
Ensembl chr12:59,005,169...59,058,803 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 increases expression ISO Cyclophosphamide results in increased expression of SERPINE1 mRNA CTD PMID:23558518 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
G Sesn2 sestrin 2 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of SESN2 mRNA CTD PMID:24356939 NCBI chr 4:132,220,115...132,237,767
Ensembl chr 4:132,219,343...132,237,812 		JBrowse link
G Sfn stratifin increases expression ISO Cyclophosphamide results in increased expression of SFN mRNA CTD PMID:21527772 NCBI chr 4:133,327,867...133,329,163
Ensembl chr 4:133,327,867...133,329,479 		JBrowse link
G Sgce sarcoglycan, epsilon affects response to substance ISO SGCE protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 6:4,674,350...4,747,180
Ensembl chr 6:4,674,350...4,747,207 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of SGK1 mRNA CTD PMID:24356939 NCBI chr10:21,758,083...21,875,802
Ensembl chr10:21,758,083...21,875,802 		JBrowse link
G Sharpin SHANK-associated RH domain interacting protein decreases expression ISO Cyclophosphamide results in decreased expression of SHARPIN mRNA CTD PMID:27281708 NCBI chr15:76,231,240...76,235,310
Ensembl chr15:76,231,240...76,235,311 		JBrowse link
G Sirt5 sirtuin 5 increases expression ISO Cyclophosphamide results in increased expression of SIRT5 mRNA CTD PMID:27281708 NCBI chr13:43,518,849...43,549,073
Ensembl chr13:43,518,972...43,548,679 		JBrowse link
G Sit1 suppression inducing transmembrane adaptor 1 decreases expression EXP Cyclophosphamide results in decreased expression of SIT1 mRNA CTD PMID:21041162 NCBI chr 4:43,482,083...43,483,709
Ensembl chr 4:43,482,081...43,483,734 		JBrowse link
G Slc18a3 solute carrier family 18 (vesicular monoamine), member 3 increases expression
multiple interactions		 ISO Cyclophosphamide results in increased expression of SLC18A3 protein
O-1602 compound inhibits the reaction [Cyclophosphamide results in increased expression of SLC18A3 protein]		 CTD PMID:32615180 NCBI chr14:32,184,394...32,186,807
Ensembl chr14:32,184,395...32,186,807 		JBrowse link
G Slc22a3 solute carrier family 22 (organic cation transporter), member 3 multiple interactions
increases expression		 ISO O-1602 compound inhibits the reaction [Cyclophosphamide results in increased expression of SLC22A3 protein] CTD PMID:32615180 NCBI chr17:12,638,859...12,726,591
Ensembl chr17:12,637,847...12,726,591 		JBrowse link
G Slc22a5 solute carrier family 22 (organic cation transporter), member 5 multiple interactions
decreases expression		 ISO Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of SLC22A5 mRNA]; Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of SLC22A5 protein]
Cyclophosphamide results in decreased expression of SLC22A5 mRNA; Cyclophosphamide results in decreased expression of SLC22A5 protein		 CTD PMID:22701146 NCBI chr11:53,755,368...53,782,609
Ensembl chr11:53,755,368...53,782,486 		JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 decreases expression EXP Cyclophosphamide results in decreased expression of SLC2A2 mRNA CTD PMID:15331540 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508 		JBrowse link
G Slc2a6 solute carrier family 2 (facilitated glucose transporter), member 6 increases expression ISO Cyclophosphamide results in increased expression of SLC2A6 mRNA CTD PMID:21527772 NCBI chr 2:26,911,375...26,918,011
Ensembl chr 2:26,911,375...26,918,010 		JBrowse link
G Slc39a13 solute carrier family 39 (metal ion transporter), member 13 increases expression ISO Cyclophosphamide results in increased expression of SLC39A13 mRNA CTD PMID:27281708 NCBI chr 2:90,892,136...90,900,754
Ensembl chr 2:90,892,136...90,900,762 		JBrowse link
G Slc39a14 solute carrier family 39 (zinc transporter), member 14 increases expression ISO Cyclophosphamide results in increased expression of SLC39A14 mRNA CTD PMID:27281708 NCBI chr14:70,540,916...70,588,873
Ensembl chr14:70,540,918...70,588,874 		JBrowse link
G Slc39a5 solute carrier family 39 (metal ion transporter), member 5 increases expression ISO Cyclophosphamide results in increased expression of SLC39A5 mRNA; Cyclophosphamide results in increased expression of SLC39A5 protein CTD PMID:27281708 NCBI chr10:128,231,796...128,237,145
Ensembl chr10:128,231,800...128,237,098 		JBrowse link
G Slc39a6 solute carrier family 39 (metal ion transporter), member 6 increases expression ISO Cyclophosphamide results in increased expression of SLC39A6 mRNA CTD PMID:27281708 NCBI chr18:24,712,938...24,736,874
Ensembl chr18:24,712,938...24,736,874 		JBrowse link
G Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of SLC3A2 mRNA CTD PMID:24356939 NCBI chr19:8,684,931...8,700,733
Ensembl chr19:8,684,246...8,700,733 		JBrowse link
G Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 decreases expression
multiple interactions		 EXP Cyclophosphamide results in decreased expression of SLC40A1 protein
Dexrazoxane inhibits the reaction [Cyclophosphamide results in decreased expression of SLC40A1 protein]		 CTD PMID:37690746 NCBI chr 1:45,947,230...45,965,690
Ensembl chr 1:45,947,228...45,965,683 		JBrowse link
G Slc43a1 solute carrier family 43, member 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of SLC43A1 mRNA CTD PMID:24356939 NCBI chr 2:84,669,196...84,693,930
Ensembl chr 2:84,669,194...84,693,938 		JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 affects expression
decreases expression
multiple interactions		 ISO
EXP		 Cyclophosphamide affects the expression of SLC7A11 mRNA
Cyclophosphamide metabolite results in decreased expression of SLC7A11 mRNA
Dexrazoxane inhibits the reaction [Cyclophosphamide results in decreased expression of SLC7A11 protein]		 CTD PMID:23824090 PMID:24356939 PMID:37690746 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063 		JBrowse link
G Slfn4 schlafen 4 increases expression EXP Cyclophosphamide results in increased expression of SLFN4 mRNA CTD PMID:15331540 NCBI chr11:83,066,001...83,081,042
Ensembl chr11:83,066,012...83,081,042 		JBrowse link
G Slit1 slit guidance ligand 1 decreases expression ISO Cyclophosphamide results in decreased expression of SLIT1 mRNA CTD PMID:20849824 NCBI chr19:41,586,263...41,735,714
Ensembl chr19:41,588,696...41,732,104 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor decreases expression EXP Cyclophosphamide results in decreased expression of SLPI mRNA CTD PMID:15331540 NCBI chr 2:164,195,990...164,231,086
Ensembl chr 2:164,195,990...164,231,015 		JBrowse link
G Snx10 sorting nexin 10 increases expression EXP Cyclophosphamide results in increased expression of SNX10 mRNA CTD PMID:15331540 NCBI chr 6:51,500,882...51,567,659
Ensembl chr 6:51,500,881...51,567,659 		JBrowse link
G Soat1 sterol O-acyltransferase 1 affects response to substance ISO SOAT1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 1:156,255,678...156,301,898
Ensembl chr 1:156,252,095...156,301,901 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 decreases expression EXP Cyclophosphamide results in decreased expression of SOCS1 mRNA CTD PMID:21041162 NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400 		JBrowse link
G Socs7 suppressor of cytokine signaling 7 increases expression ISO Cyclophosphamide results in increased expression of SOCS7 mRNA CTD PMID:11599041 NCBI chr11:97,253,044...97,289,368
Ensembl chr11:97,253,261...97,289,368 		JBrowse link
G Sod1 superoxide dismutase 1, soluble decreases expression
multiple interactions
decreases activity		 EXP
ISO		 Cyclophosphamide results in decreased expression of SOD1 mRNA
[Doxorubicin co-treated with Cyclophosphamide] results in increased expression of SOD1 protein; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of SOD1 mRNA]
allyl sulfide inhibits the reaction [Cyclophosphamide results in decreased activity of SOD1 protein]; Quercetin inhibits the reaction [Cyclophosphamide results in decreased activity of SOD1 protein]		 CTD PMID:23542512 PMID:29228376 PMID:31779506 PMID:35906875 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial increases expression
decreases expression
affects response to substance		 EXP
ISO		 Cyclophosphamide results in increased expression of SOD2 mRNA
Cyclophosphamide results in decreased expression of SOD2 mRNA
SOD2 polymorphism affects the susceptibility to Cyclophosphamide		 CTD PMID:11599041 PMID:11906922 PMID:15331540 PMID:20309628 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Sord sorbitol dehydrogenase decreases activity
multiple interactions		 ISO Cyclophosphamide results in decreased activity of SORD protein
Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased activity of SORD protein]		 CTD PMID:25446862 NCBI chr 2:122,065,320...122,095,818
Ensembl chr 2:122,065,230...122,095,821 		JBrowse link
G Sp2 Sp2 transcription factor decreases expression ISO Cyclophosphamide results in decreased expression of SP2 mRNA CTD PMID:27281708 NCBI chr11:96,844,158...96,873,785
Ensembl chr11:96,844,167...96,873,785 		JBrowse link
G Sparc secreted acidic cysteine rich glycoprotein decreases expression
increases expression		 EXP
ISO		 Cyclophosphamide results in decreased expression of SPARC mRNA
Cyclophosphamide results in increased expression of SPARC mRNA		 CTD PMID:15331540 PMID:17403535 NCBI chr11:55,284,985...55,310,906
Ensembl chr11:55,285,326...55,314,009 		JBrowse link
G Spp1 secreted phosphoprotein 1 affects response to substance
affects expression
increases expression		 ISO SPP1 protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide affects the expression of SPP1 mRNA
Cyclophosphamide results in increased expression of SPP1 mRNA		 CTD PMID:16217747 PMID:20623750 PMID:23558518 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916 		JBrowse link
G Srek1ip1 splicing regulatory glutamine/lysine-rich protein 1interacting protein 1 increases expression ISO Cyclophosphamide results in increased expression of SREK1IP1 mRNA CTD PMID:27281708 NCBI chr13:104,953,696...104,975,805
Ensembl chr13:104,928,992...104,975,782 		JBrowse link
G Srm spermidine synthase multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of SRM mRNA CTD PMID:16322899 NCBI chr 4:148,675,970...148,679,076
Ensembl chr 4:148,675,960...148,679,450 		JBrowse link
G Ssrp1 structure specific recognition protein 1 increases expression ISO Cyclophosphamide results in increased expression of SSRP1 mRNA CTD PMID:11599041 NCBI chr 2:84,867,519...84,877,453
Ensembl chr 2:84,867,578...84,877,453 		JBrowse link
G St13 suppression of tumorigenicity 13 increases expression ISO Cyclophosphamide results in increased expression of ST13 mRNA CTD PMID:11599041 NCBI chr15:81,247,869...81,284,278
Ensembl chr15:81,247,870...81,284,278 		JBrowse link
G St14 suppression of tumorigenicity 14 (colon carcinoma) multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of ST14 mRNA CTD PMID:16322899 NCBI chr 9:30,999,886...31,043,138
Ensembl chr 9:31,000,698...31,043,149 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression EXP Cyclophosphamide results in increased expression of STAT1 mRNA CTD PMID:21041162 NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases phosphorylation
decreases phosphorylation
multiple interactions
decreases expression		 ISO
EXP		 Cyclophosphamide results in increased phosphorylation of STAT3 protein
Cyclophosphamide results in decreased phosphorylation of STAT3 protein
chrysin inhibits the reaction [Cyclophosphamide results in increased phosphorylation of STAT3 protein]
ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of STAT3 mRNA]		 CTD PMID:19625377 PMID:21880982 PMID:37263553 PMID:37853057 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B decreases expression EXP Cyclophosphamide results in decreased expression of STAT5B mRNA CTD PMID:21041162 NCBI chr11:100,671,557...100,741,407
Ensembl chr11:100,671,557...100,741,550 		JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression EXP
ISO		 Cyclophosphamide results in decreased expression of STIP1 mRNA CTD PMID:11906922 PMID:15331540 NCBI chr19:6,998,064...7,017,394
Ensembl chr19:6,998,070...7,017,335 		JBrowse link
G Stk39 serine/threonine kinase 39 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of STK39 mRNA CTD PMID:16322899 NCBI chr 2:68,040,789...68,302,381
Ensembl chr 2:68,040,789...68,302,612 		JBrowse link
G Stk4 serine/threonine kinase 4 decreases expression EXP Cyclophosphamide results in decreased expression of STK4 mRNA CTD PMID:21041162 NCBI chr 2:163,916,033...163,997,444
Ensembl chr 2:163,912,242...163,997,444 		JBrowse link
G Stmn3 stathmin-like 3 increases expression ISO Cyclophosphamide results in increased expression of STMN3 mRNA CTD PMID:21527772 NCBI chr 2:180,948,252...180,956,293
Ensembl chr 2:180,948,252...180,956,293 		JBrowse link
G Stom stomatin increases expression ISO Cyclophosphamide results in increased expression of STOM mRNA CTD PMID:21527772 NCBI chr 2:35,204,002...35,227,021
Ensembl chr 2:35,203,998...35,226,988 		JBrowse link
G Sun1 Sad1 and UNC84 domain containing 1 decreases expression ISO Cyclophosphamide results in decreased expression of SUN1 mRNA CTD PMID:27281708 NCBI chr 5:139,186,313...139,235,594
Ensembl chr 5:139,186,392...139,235,595 		JBrowse link
G Tac1 tachykinin 1 multiple interactions
affects expression
increases expression
increases secretion		 ISO
EXP		 Botulinum Toxins, Type A inhibits the reaction [Cyclophosphamide results in increased secretion of TAC1 protein]
Cyclophosphamide affects the expression of TAC1 mRNA
Cyclophosphamide results in increased expression of TAC1 protein		 CTD PMID:11312054 PMID:18184328 PMID:18563302 PMID:22842586 NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834 		JBrowse link
G Tacr1 tachykinin receptor 1 multiple interactions
increases expression
decreases response to substance		 EXP
ISO		 [alpha-amyrin co-treated with beta-amyrin] inhibits the reaction [Cyclophosphamide results in increased expression of TACR1 protein]
TACR1 gene mutant form results in decreased susceptibility to Cyclophosphamide
GR 82334 inhibits the reaction [Cyclophosphamide results in increased expression of TACR1 protein]; Suramin inhibits the reaction [Cyclophosphamide results in increased expression of TACR1 protein]		 CTD PMID:10854767 PMID:18210232 PMID:23666265 NCBI chr 6:82,378,990...82,537,085
Ensembl chr 6:82,379,315...82,537,085 		JBrowse link
G Tafa5 TAFA chemokine like family member 5 increases expression EXP Cyclophosphamide results in increased expression of TAFA5 mRNA CTD PMID:21621594 NCBI chr15:87,428,405...87,643,565
Ensembl chr15:87,428,500...87,643,565 		JBrowse link
G Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) increases expression ISO Cyclophosphamide results in increased expression of TAP1 mRNA CTD PMID:21527772 NCBI chr17:34,406,530...34,416,199
Ensembl chr17:34,406,527...34,416,199 		JBrowse link
G Tat tyrosine aminotransferase affects expression
decreases expression		 ISO Cyclophosphamide affects the expression of TAT mRNA
Cyclophosphamide results in decreased expression of TAT mRNA		 CTD PMID:18246545 NCBI chr 8:110,712,710...110,726,436
Ensembl chr 8:110,717,069...110,726,435 		JBrowse link
G Tbx21 T-box 21 multiple interactions
decreases expression		 EXP Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TBX21 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of TBX21 protein] CTD PMID:32151603 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157 		JBrowse link
G Tcf7 transcription factor 7, T cell specific decreases expression EXP Cyclophosphamide results in decreased expression of TCF7 mRNA CTD PMID:21041162 NCBI chr11:52,137,347...52,174,211
Ensembl chr11:52,143,198...52,174,158 		JBrowse link
G Tcp1 t-complex protein 1 decreases expression
increases expression		 ISO Cyclophosphamide results in decreased expression of TCP1 mRNA
Cyclophosphamide results in increased expression of TCP1 mRNA		 CTD PMID:11599041 PMID:11906922 NCBI chr17:13,135,216...13,143,954
Ensembl chr17:13,134,588...13,143,954 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase increases activity
multiple interactions		 ISO Cyclophosphamide results in increased activity of TDO2 protein
Quercetin inhibits the reaction [Cyclophosphamide results in increased activity of TDO2 protein]		 CTD PMID:35906875 NCBI chr 3:81,865,719...81,883,035
Ensembl chr 3:81,864,397...81,883,509 		JBrowse link
G Tex30 testis expressed 30 decreases expression ISO Cyclophosphamide results in decreased expression of TEX30 mRNA CTD PMID:17403535 NCBI chr 1:44,125,773...44,141,650
Ensembl chr 1:44,125,773...44,141,601 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
multiple interactions
affects expression
increases secretion		 EXP
ISO		 Cyclophosphamide results in increased expression of TGFB1 mRNA
DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]]; TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]
Cyclophosphamide affects the expression of TGFB1 mRNA
Cyclophosphamide results in increased expression of and results in increased activity of TGFB1 protein; naringin inhibits the reaction [Cyclophosphamide results in increased expression of TGFB1 mRNA]
Cyclophosphamide results in increased secretion of TGFB1 protein
Cyclophosphamide results in increased expression of TGFB1 mRNA; Cyclophosphamide results in increased expression of TGFB1 protein		 CTD PMID:9509296 PMID:12624490 PMID:19691848 PMID:21068404 PMID:23926183 More... NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression ISO Cyclophosphamide results in increased expression of TGFB2 mRNA CTD PMID:23558518 PMID:23926183 NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 multiple interactions
decreases expression
increases expression		 EXP
ISO		 Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TGFB3 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of TGFB3 protein]
Cyclophosphamide results in increased expression of TGFB3 mRNA; Cyclophosphamide results in increased expression of TGFB3 protein		 CTD PMID:23926183 PMID:32151603 NCBI chr12:86,103,517...86,125,815
Ensembl chr12:86,103,519...86,125,815 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor I increases expression ISO Cyclophosphamide results in increased expression of TGFBR1 mRNA; Cyclophosphamide results in increased expression of TGFBR1 protein CTD PMID:23926183 NCBI chr 4:47,353,258...47,414,926
Ensembl chr 4:47,353,222...47,414,931 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor II increases expression EXP
ISO		 Cyclophosphamide results in increased expression of TGFBR2 mRNA
Cyclophosphamide results in increased expression of TGFBR2 mRNA; Cyclophosphamide results in increased expression of TGFBR2 protein		 CTD PMID:21041162 PMID:23926183 NCBI chr 9:115,916,763...116,004,431
Ensembl chr 9:115,913,361...116,004,428 		JBrowse link
G Tgfbr3 transforming growth factor, beta receptor III increases expression ISO Cyclophosphamide results in increased expression of TGFBR3 mRNA; Cyclophosphamide results in increased expression of TGFBR3 protein CTD PMID:23926183 NCBI chr 5:107,254,433...107,437,495
Ensembl chr 5:107,254,436...107,437,495 		JBrowse link
G Thbs1 thrombospondin 1 multiple interactions
increases expression		 ISO
EXP		 axitinib inhibits the reaction [Cyclophosphamide results in increased expression of THBS1 protein]
Cyclophosphamide results in increased expression of THBS1 mRNA		 CTD PMID:15331540 PMID:18202011 NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614 		JBrowse link
G Thnsl2 threonine synthase-like 2 (bacterial) multiple interactions ISO THNSL2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 6:71,105,150...71,121,364
Ensembl chr 6:71,105,150...71,121,423 		JBrowse link
G Thy1 thymus cell antigen 1, theta decreases expression EXP Cyclophosphamide results in decreased expression of THY1 mRNA CTD PMID:21041162 NCBI chr 9:43,954,681...43,959,876
Ensembl chr 9:43,954,681...43,959,876 		JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 increases expression ISO Cyclophosphamide results in increased expression of TIMP1 mRNA CTD PMID:23558518 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
decreases expression		 ISO
EXP		 Anthocyanins inhibits the reaction [Cyclophosphamide results in decreased expression of TJP1 protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of TJP1 protein]
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TJP1 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of TJP1 protein]		 CTD PMID:25451569 PMID:32151603 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529 		JBrowse link
G Tk1 thymidine kinase 1 increases mutagenesis ISO Cyclophosphamide metabolite results in increased mutagenesis of TK1 gene CTD PMID:32087850 NCBI chr11:117,706,345...117,716,913
Ensembl chr11:117,706,352...117,716,918 		JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions
decreases expression		 EXP Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TLR2 mRNA]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of TLR2 mRNA] CTD PMID:32151603 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074 		JBrowse link
G Tlr4 toll-like receptor 4 decreases expression
multiple interactions		 EXP Cyclophosphamide results in decreased expression of TLR4 mRNA
Cyclophosphamide inhibits the reaction [Paraquat results in increased expression of TLR4 mRNA]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TLR4 mRNA]		 CTD PMID:32151603 PMID:36031164 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tlr6 toll-like receptor 6 multiple interactions
decreases expression		 EXP Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TLR6 mRNA]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of TLR6 mRNA] CTD PMID:32151603 NCBI chr 5:65,109,373...65,128,387
Ensembl chr 5:65,109,374...65,117,440 		JBrowse link
G Tlr9 toll-like receptor 9 multiple interactions
increases expression		 EXP Cyclophosphamide inhibits the reaction [Paraquat results in increased expression of TLR9 mRNA]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of TLR9 protein] CTD PMID:29753871 PMID:36031164 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082 		JBrowse link
G Tm4sf1 transmembrane 4 superfamily member 1 increases expression ISO Cyclophosphamide results in increased expression of TM4SF1 mRNA CTD PMID:17403535 NCBI chr 3:57,193,038...57,295,150
Ensembl chr 3:57,193,032...57,209,409
Ensembl chr 3:57,193,032...57,209,409 		JBrowse link
G Tm6sf1 transmembrane 6 superfamily member 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of TM6SF1 mRNA CTD PMID:24356939 NCBI chr 7:81,507,810...81,533,827
Ensembl chr 7:81,508,749...81,534,182 		JBrowse link
G Tmed3 transmembrane p24 trafficking protein 3 decreases expression EXP Cyclophosphamide results in decreased expression of TMED3 mRNA CTD PMID:15331540 NCBI chr 9:89,581,256...89,587,096
Ensembl chr 9:89,581,259...89,587,121 		JBrowse link
G Tmeff1 transmembrane protein with EGF-like and two follistatin-like domains 1 affects response to substance
decreases expression		 ISO TMEFF1 protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in decreased expression of TMEFF1 mRNA		 CTD PMID:16217747 PMID:27466211 NCBI chr 4:48,585,064...48,663,136
Ensembl chr 4:48,585,174...48,663,131 		JBrowse link
G Tmem267 transmembrane protein 267 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of TMEM267 mRNA CTD PMID:24356939 NCBI chr13:119,624,622...120,071,995
Ensembl chr13:119,624,575...120,072,595 		JBrowse link
G Tmprss2 transmembrane protease, serine 2 increases expression ISO Cyclophosphamide results in increased expression of TMPRSS2 mRNA CTD PMID:32808185 NCBI chr16:97,365,882...97,460,741
Ensembl chr16:97,365,882...97,412,395 		JBrowse link
G Tnf tumor necrosis factor affects expression
increases response to substance
decreases response to substance
multiple interactions
increases expression
decreases expression
increases secretion		 EXP
ISO		 Cyclophosphamide affects the expression of TNF mRNA
TNF protein results in increased susceptibility to Cyclophosphamide
TNF protein results in decreased susceptibility to Cyclophosphamide
Cyclophosphamide affects the expression of TNF protein
allyl sulfide inhibits the reaction [Cyclophosphamide results in increased secretion of TNF protein]; Anthocyanins inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; chrysin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Cilostazol inhibits the reaction [Cyclophosphamide results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]]; O-1602 compound inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Pentoxifylline inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Rolipram inhibits the reaction [Cyclophosphamide results in increased expression of TNF mRNA]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; thymoquinone inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]
Cyclophosphamide results in increased expression of TNF mRNA; Cyclophosphamide results in increased expression of TNF protein
[Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of TNF protein; [Cyclophosphamide co-treated with Methylprednisolone] inhibits the reaction [Paraquat results in increased expression of TNF protein]; Cyclophosphamide inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TNF mRNA]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of TNF mRNA]; ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of TNF protein]
Cyclophosphamide results in decreased expression of TNF mRNA; Cyclophosphamide results in decreased expression of TNF protein
Cyclophosphamide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]		 CTD PMID:8634684 PMID:11948286 PMID:12797522 PMID:18206168 PMID:18710439 More... NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 increases expression ISO Cyclophosphamide results in increased expression of TNFAIP3 mRNA CTD PMID:21873647 NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405 		JBrowse link
G Tnfrsf14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) increases expression ISO Cyclophosphamide results in increased expression of TNFRSF14 mRNA CTD PMID:21527772 NCBI chr 4:155,002,944...155,013,077
Ensembl chr 4:155,006,390...155,013,020 		JBrowse link
G Tnfrsf18 tumor necrosis factor receptor superfamily, member 18 decreases expression EXP Cyclophosphamide results in decreased expression of TNFRSF18 mRNA CTD PMID:15591121 NCBI chr 4:156,110,779...156,113,351
Ensembl chr 4:156,110,621...156,113,352 		JBrowse link
G Tnfrsf19 tumor necrosis factor receptor superfamily, member 19 multiple interactions
increases expression		 EXP 5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline inhibits the reaction [Cyclophosphamide results in increased expression of TNFRSF19 mRNA] CTD PMID:30760223 NCBI chr14:61,201,283...61,284,304
Ensembl chr14:61,201,324...61,283,939 		JBrowse link
G Tnfsf9 tumor necrosis factor (ligand) superfamily, member 9 increases expression ISO Cyclophosphamide results in increased expression of TNFSF9 mRNA CTD PMID:21527772 NCBI chr17:57,412,113...57,414,757
Ensembl chr17:57,412,325...57,414,757 		JBrowse link
G Tnni3 troponin I, cardiac 3 increases expression
multiple interactions		 ISO Cyclophosphamide results in increased expression of TNNI3 protein
Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of TNNI3 protein]]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of TNNI3 protein]		 CTD PMID:17562616 PMID:18548196 PMID:35762198 NCBI chr 7:4,521,304...4,526,228
Ensembl chr 7:4,521,304...4,527,228 		JBrowse link
G Top2a topoisomerase (DNA) II alpha multiple interactions
increases expression		 ISO TOP2A protein affects the susceptibility to [Cyclophosphamide co-treated with Epirubicin co-treated with Fluorouracil]; TOP2A protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]
Cyclophosphamide results in increased expression of TOP2A mRNA		 CTD PMID:11599041 PMID:16682728 PMID:18465341 NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015 		JBrowse link
G Tpd52 tumor protein D52 decreases expression ISO Cyclophosphamide results in decreased expression of TPD52 mRNA CTD PMID:21873647 NCBI chr 3:8,991,590...9,069,824
Ensembl chr 3:8,990,653...9,069,783 		JBrowse link
G Tpm1 tropomyosin 1, alpha affects response to substance ISO TPM1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 9:66,929,872...66,956,954
Ensembl chr 9:66,929,872...66,956,688 		JBrowse link
G Trib3 tribbles pseudokinase 3 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of TRIB3 mRNA CTD PMID:24356939 NCBI chr 2:152,179,345...152,185,980
Ensembl chr 2:152,179,342...152,185,952 		JBrowse link
G Trim32 tripartite motif-containing 32 increases expression ISO Cyclophosphamide results in increased expression of TRIM32 mRNA CTD PMID:27281708 NCBI chr 4:65,523,223...65,534,477
Ensembl chr 4:65,523,223...65,534,475 		JBrowse link
G Trim58 tripartite motif-containing 58 increases expression ISO Cyclophosphamide results in increased expression of TRIM58 mRNA CTD PMID:27281708 NCBI chr11:58,531,232...58,543,277
Ensembl chr11:58,531,291...58,543,230 		JBrowse link
G Triml1 tripartite motif family-like 1 decreases expression ISO Cyclophosphamide results in decreased expression of TRIML1 mRNA CTD PMID:27281708 NCBI chr 8:43,582,843...43,633,531
Ensembl chr 8:43,582,844...43,594,523 		JBrowse link
G Trp53 transformation related protein 53 multiple interactions
affects response to substance
increases mutagenesis
increases expression
increases activity		 ISO
EXP		 astaxanthine inhibits the reaction [Cyclophosphamide results in increased expression of TP53 protein]; chlorophyllin inhibits the reaction [Cyclophosphamide results in increased mutagenesis of TP53 exon]; Curcumin inhibits the reaction [Cyclophosphamide results in increased mutagenesis of TP53 exon]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased expression of TP53 mRNA]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of TP53 mRNA]
TP53 protein affects the susceptibility to Cyclophosphamide
TRP53 affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in increased expression of TP53 mRNA; Cyclophosphamide results in increased expression of TP53 protein
TP53 protein promotes the reaction [Methotrexate results in increased susceptibility to Cyclophosphamide metabolite]
Cyclophosphamide metabolite results in increased activity of TP53 protein		 CTD PMID:9610789 PMID:10766175 PMID:15182437 PMID:19227835 PMID:20038455 More... NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 multiple interactions ISO [2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide binds to and results in decreased activity of TRPA1 protein] which results in decreased susceptibility to Cyclophosphamide CTD PMID:23523557 NCBI chr 1:14,942,868...14,989,086
Ensembl chr 1:14,942,872...14,989,086 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 decreases expression ISO Cyclophosphamide results in decreased expression of TRPV1 mRNA alternative form CTD PMID:18797299 NCBI chr11:73,124,975...73,152,148
Ensembl chr11:73,125,118...73,152,068 		JBrowse link
G Try4 trypsin 4 affects response to substance ISO PRSS3 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 6:41,279,206...41,282,467
Ensembl chr 6:41,279,203...41,282,466 		JBrowse link
G Tuba4a tubulin, alpha 4A increases expression ISO Cyclophosphamide results in increased expression of TUBA4A mRNA CTD PMID:21527772 NCBI chr 1:75,190,867...75,197,905
Ensembl chr 1:75,190,872...75,196,509 		JBrowse link
G Tubb2b tubulin, beta 2B class IIB decreases expression EXP Cyclophosphamide results in decreased expression of TUBB2B mRNA CTD PMID:21041162 NCBI chr13:34,310,991...34,314,337
Ensembl chr13:34,310,731...34,314,449 		JBrowse link
G Tug1 taurine upregulated gene 1 multiple interactions
decreases expression		 ISO sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in decreased expression of TUG1 mRNA]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased expression of TUG1 mRNA] CTD PMID:32197949 NCBI chr11:3,589,313...3,599,021
Ensembl chr11:3,589,785...3,599,673 		JBrowse link
G Txn1 thioredoxin 1 multiple interactions
decreases expression		 EXP ganoderic acid A inhibits the reaction [Cyclophosphamide results in decreased expression of TXN protein] CTD PMID:30506662 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411 		JBrowse link
G Txnip thioredoxin interacting protein multiple interactions
increases expression		 EXP ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of TXNIP protein] CTD PMID:30506662 NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199 		JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases activity EXP Cyclophosphamide results in decreased activity of TXNRD1 protein CTD PMID:19168513 NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546 		JBrowse link
G Tymp thymidine phosphorylase multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] results in increased expression of TYMP protein; [Epirubicin co-treated with Cyclophosphamide] results in increased expression of TYMP protein CTD PMID:15150550 NCBI chr15:89,255,834...89,261,282
Ensembl chr15:89,256,134...89,261,242 		JBrowse link
G Tyrobp TYRO protein tyrosine kinase binding protein increases expression EXP Cyclophosphamide results in increased expression of TYROBP mRNA CTD PMID:21041162 NCBI chr 7:30,113,207...30,117,007
Ensembl chr 7:30,113,185...30,117,010 		JBrowse link
G Ubd ubiquitin D increases expression EXP Cyclophosphamide results in increased expression of UBD mRNA CTD PMID:15331540 NCBI chr17:37,504,783...37,506,992
Ensembl chr17:37,504,783...37,506,986 		JBrowse link
G Ubr7 ubiquitin protein ligase E3 component n-recognin 7 (putative) increases expression ISO Cyclophosphamide results in increased expression of UBR7 mRNA CTD PMID:27281708 NCBI chr12:102,724,234...102,743,960
Ensembl chr12:102,724,226...102,743,966 		JBrowse link
G Ucp1 uncoupling protein 1 (mitochondrial, proton carrier) decreases expression ISO Cyclophosphamide metabolite results in decreased expression of UCP1 mRNA CTD PMID:24356939 NCBI chr 8:84,016,977...84,025,085
Ensembl chr 8:84,016,981...84,025,081 		JBrowse link
G Umod uromodulin multiple interactions
decreases expression		 ISO O-1602 compound inhibits the reaction [Cyclophosphamide results in decreased expression of UMOD protein] CTD PMID:32615180 NCBI chr 7:119,061,931...119,078,485
Ensembl chr 7:119,061,934...119,078,505 		JBrowse link
G Ung uracil DNA glycosylase decreases expression ISO Cyclophosphamide results in decreased expression of UNG mRNA CTD PMID:11056294 NCBI chr 5:114,268,427...114,277,382
Ensembl chr 5:114,268,447...114,277,384 		JBrowse link
G Upk1a uroplakin 1A decreases expression
multiple interactions		 ISO Cyclophosphamide results in decreased expression of UPK1A mRNA
Mesna inhibits the reaction [Cyclophosphamide results in decreased expression of UPK1A mRNA]		 CTD PMID:19654953 PMID:20186394 NCBI chr 7:30,302,517...30,312,159
Ensembl chr 7:30,302,517...30,312,272 		JBrowse link
G Upk1b uroplakin 1B decreases expression
multiple interactions		 ISO Cyclophosphamide results in decreased expression of UPK1B mRNA
Mesna inhibits the reaction [Cyclophosphamide results in decreased expression of UPK1B mRNA]		 CTD PMID:19654953 PMID:20186394 NCBI chr16:38,593,544...38,620,565
Ensembl chr16:38,593,546...38,620,690 		JBrowse link
G Upk2 uroplakin 2 decreases expression
multiple interactions		 ISO
EXP		 Cyclophosphamide results in decreased expression of UPK2 mRNA; Cyclophosphamide results in decreased expression of UPK2 protein
Mesna inhibits the reaction [Cyclophosphamide results in decreased expression of UPK2 mRNA]; Mesna inhibits the reaction [Cyclophosphamide results in decreased expression of UPK2 protein]
Mesna inhibits the reaction [Cyclophosphamide results in decreased expression of UPK2 mRNA]; Mesna inhibits the reaction [Cyclophosphamide results in decreased expression of UPK2 protein]; S-allylcysteine inhibits the reaction [Cyclophosphamide results in decreased expression of UPK2 mRNA]; S-allylcysteine inhibits the reaction [Cyclophosphamide results in decreased expression of UPK2 protein]		 CTD PMID:19654953 PMID:20186394 PMID:27234646 NCBI chr 9:44,364,012...44,366,064
Ensembl chr 9:44,364,012...44,366,273 		JBrowse link
G Upk3a uroplakin 3A decreases expression
multiple interactions		 ISO Cyclophosphamide results in decreased expression of UPK3A mRNA; Cyclophosphamide results in decreased expression of UPK3A protein
Mesna inhibits the reaction [Cyclophosphamide results in decreased expression of UPK3A mRNA]; Mesna inhibits the reaction [Cyclophosphamide results in decreased expression of UPK3A protein]		 CTD PMID:19654953 PMID:20186394 NCBI chr15:84,901,342...84,906,761
Ensembl chr15:84,901,342...84,906,748 		JBrowse link
G Usp36 ubiquitin specific peptidase 36 increases expression ISO Cyclophosphamide results in increased expression of USP36 mRNA CTD PMID:20849824 NCBI chr11:118,150,477...118,181,086
Ensembl chr11:118,150,477...118,181,070 		JBrowse link
G Usp44 ubiquitin specific peptidase 44 decreases expression ISO Cyclophosphamide results in decreased expression of USP44 mRNA CTD PMID:27281708 NCBI chr10:93,655,831...93,696,792
Ensembl chr10:93,667,417...93,693,950 		JBrowse link
G Usp5 ubiquitin specific peptidase 5 (isopeptidase T) multiple interactions
increases expression		 EXP 3-cyanoalanine inhibits the reaction [[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of USP5 protein]; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of USP5 protein
Cyclophosphamide results in increased expression of USP5 protein		 CTD PMID:29129814 NCBI chr 6:124,791,982...124,806,404
Ensembl chr 6:124,791,982...124,806,447 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression EXP Cyclophosphamide results in increased expression of VCAM1 mRNA CTD PMID:15331540 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337 		JBrowse link
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor increases expression ISO Cyclophosphamide results in increased expression of VDR mRNA CTD PMID:27281708 NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression
affects expression
decreases expression		 EXP
ISO		 Cyclophosphamide promotes the reaction [NGF results in increased expression of VEGFA mRNA]
Cyclophosphamide results in increased expression of VEGFA mRNA
Cyclophosphamide affects the expression of VEGFA protein
Cyclophosphamide metabolite results in decreased expression of VEGFA mRNA		 CTD PMID:18632792 PMID:24356939 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
G Vim vimentin affects expression ISO Cyclophosphamide affects the expression of VIM mRNA CTD PMID:10859244 NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637 		JBrowse link
G Vip vasoactive intestinal polypeptide multiple interactions
affects expression
affects response to substance		 EXP
ISO		 VIP protein affects the reaction [Cyclophosphamide results in increased expression of NGF protein]; VIP protein inhibits the reaction [Cyclophosphamide results in increased expression of CXCL1 protein]; VIP protein inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]
Cyclophosphamide affects the expression of VIP mRNA
VIP affects the susceptibility to Cyclophosphamide		 CTD PMID:18299998 PMID:18483878 PMID:18563302 NCBI chr10:5,589,131...5,597,617
Ensembl chr10:5,589,218...5,597,617 		JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 increases expression ISO Cyclophosphamide results in increased expression of VIPR1 mRNA CTD PMID:18563302 NCBI chr 9:121,471,782...121,502,020
Ensembl chr 9:121,471,782...121,502,020 		JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 affects expression ISO Cyclophosphamide affects the expression of VIPR2 mRNA CTD PMID:18563302 NCBI chr12:116,041,040...116,117,842
Ensembl chr12:116,041,346...116,109,881 		JBrowse link
G Vldlr very low density lipoprotein receptor decreases expression ISO Cyclophosphamide metabolite results in decreased expression of VLDLR mRNA CTD PMID:24356939 NCBI chr19:27,190,070...27,231,631
Ensembl chr19:27,193,884...27,231,631 		JBrowse link
G Was Wiskott-Aldrich syndrome decreases expression EXP Cyclophosphamide results in decreased expression of WAS mRNA CTD PMID:21041162 NCBI chr  X:7,947,705...7,956,730
Ensembl chr  X:7,947,692...7,956,737 		JBrowse link
G Xaf1 XIAP associated factor 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of XAF1 mRNA CTD PMID:24356939 NCBI chr11:72,192,229...72,204,560
Ensembl chr11:72,192,455...72,204,559 		JBrowse link
G Xdh xanthine dehydrogenase increases activity
multiple interactions		 ISO Cyclophosphamide results in increased activity of XDH protein
Rutin inhibits the reaction [Cyclophosphamide results in increased activity of XDH protein]		 CTD PMID:25753322 NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191 		JBrowse link
G Xist inactive X specific transcripts increases expression EXP Cyclophosphamide results in increased expression of XIST mRNA CTD PMID:15331540 NCBI chr  X:102,503,979...102,526,839
Ensembl chr  X:102,503,972...102,526,860 		JBrowse link
G Xpc xeroderma pigmentosum, complementation group C affects expression
increases expression		 ISO Cyclophosphamide affects the expression of XPC mRNA
Cyclophosphamide results in increased expression of XPC mRNA		 CTD PMID:11056294 PMID:29445054 NCBI chr 6:91,466,287...91,492,870
Ensembl chr 6:91,466,287...91,492,870 		JBrowse link
G Xrcc1 X-ray repair complementing defective repair in Chinese hamster cells 1 decreases expression ISO Cyclophosphamide results in decreased expression of XRCC1 mRNA CTD PMID:11056294 NCBI chr 7:24,246,124...24,272,863
Ensembl chr 7:24,245,714...24,272,865 		JBrowse link
G Xrcc6 X-ray repair complementing defective repair in Chinese hamster cells 6 decreases expression EXP Cyclophosphamide results in decreased expression of XRCC6 mRNA CTD PMID:21041162 NCBI chr15:81,868,805...81,924,286
Ensembl chr15:81,872,036...81,924,286 		JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase decreases expression EXP Cyclophosphamide results in decreased expression of ZAP70 mRNA CTD PMID:21041162 NCBI chr 1:36,800,912...36,821,899
Ensembl chr 1:36,800,879...36,821,899 		JBrowse link
G Zbtb33 zinc finger and BTB domain containing 33 increases expression ISO Cyclophosphamide results in increased expression of ZBTB33 mRNA CTD PMID:27281708 NCBI chr  X:37,278,670...37,285,923
Ensembl chr  X:37,278,670...37,285,923 		JBrowse link
G Zbtb41 zinc finger and BTB domain containing 41 increases expression ISO Cyclophosphamide results in increased expression of ZBTB41 mRNA CTD PMID:27281708 NCBI chr 1:139,349,916...139,380,743
Ensembl chr 1:139,350,026...139,380,743 		JBrowse link
G Zc3h12b zinc finger CCCH-type containing 12B decreases expression ISO Cyclophosphamide results in decreased expression of ZC3H12B mRNA CTD PMID:27281708 NCBI chr  X:94,755,206...94,976,262
Ensembl chr  X:94,755,284...94,976,243 		JBrowse link
G Zdhhc1 zinc finger, DHHC domain containing 1 decreases expression ISO Cyclophosphamide results in decreased expression of ZDHHC1 mRNA CTD PMID:27281708 NCBI chr 8:106,199,055...106,223,694
Ensembl chr 8:106,199,055...106,223,534 		JBrowse link
G Zfp142 zinc finger protein 142 decreases expression ISO Cyclophosphamide results in decreased expression of ZFP142 mRNA CTD PMID:27281708 NCBI chr 1:74,605,490...74,627,308
Ensembl chr 1:74,604,286...74,627,405 		JBrowse link
G Zfp169 zinc finger protein 169 decreases expression ISO Cyclophosphamide results in decreased expression of ZFP169 mRNA CTD PMID:27281708 NCBI chr13:48,634,239...48,666,969
Ensembl chr13:48,641,123...48,666,927 		JBrowse link
G Zfp219 zinc finger protein 219 increases expression ISO Cyclophosphamide results in increased expression of ZFP219 mRNA CTD PMID:27281708 NCBI chr14:52,243,532...52,258,597
Ensembl chr14:52,243,534...52,258,190 		JBrowse link
G Zfp24 zinc finger protein 24 increases expression ISO Cyclophosphamide results in increased expression of ZFP24 mRNA CTD PMID:27281708 NCBI chr18:24,142,774...24,155,294
Ensembl chr18:24,142,759...24,153,867 		JBrowse link
G Zfp263 zinc finger protein 263 increases expression ISO Cyclophosphamide results in increased expression of ZFP263 mRNA CTD PMID:27281708 NCBI chr16:3,561,883...3,568,654
Ensembl chr16:3,561,957...3,568,654 		JBrowse link
G Zfp280d zinc finger protein 280D increases expression ISO Cyclophosphamide results in increased expression of ZFP280D mRNA CTD PMID:27281708 NCBI chr 9:72,181,900...72,271,061
Ensembl chr 9:72,182,142...72,271,059 		JBrowse link
G Zfp318 zinc finger protein 318 decreases expression ISO Cyclophosphamide results in decreased expression of ZFP318 mRNA CTD PMID:27281708 NCBI chr17:46,694,444...46,731,846
Ensembl chr17:46,694,657...46,731,846 		JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 decreases expression ISO Cyclophosphamide results in decreased expression of ZFP36L1 mRNA CTD PMID:27281708 NCBI chr12:80,154,534...80,159,787
Ensembl chr12:80,154,528...80,159,787 		JBrowse link
G Zfp385a zinc finger protein 385A decreases expression ISO Cyclophosphamide results in decreased expression of ZFP385A mRNA CTD PMID:27281708 NCBI chr15:103,222,322...103,248,537
Ensembl chr15:103,222,322...103,248,520 		JBrowse link
G Zfp385c zinc finger protein 385C increases expression ISO Cyclophosphamide results in increased expression of ZFP385C mRNA CTD PMID:27281708 NCBI chr11:100,517,045...100,583,292
Ensembl chr11:100,518,369...100,583,281 		JBrowse link
G Zfp414 zinc finger protein 414 increases expression ISO Cyclophosphamide results in increased expression of ZFP414 mRNA CTD PMID:27281708 NCBI chr17:33,848,066...33,850,690
Ensembl chr17:33,848,064...33,850,753 		JBrowse link
G Zfp459 zinc finger protein 459 increases expression EXP Cyclophosphamide results in increased expression of ZFP459 mRNA CTD PMID:21621594 NCBI chr13:67,553,831...67,569,537
Ensembl chr13:67,553,828...67,569,537 		JBrowse link
G Zfp513 zinc finger protein 513 increases expression ISO Cyclophosphamide results in increased expression of ZFP513 mRNA CTD PMID:27281708 NCBI chr 5:31,356,325...31,360,007
Ensembl chr 5:31,356,325...31,359,647 		JBrowse link
G Zfp532 zinc finger protein 532 decreases expression ISO Cyclophosphamide results in decreased expression of ZFP532 mRNA CTD PMID:27281708 NCBI chr18:65,713,301...65,822,514
Ensembl chr18:65,712,983...65,822,514 		JBrowse link
G Zfp622 zinc finger protein 622 increases expression ISO Cyclophosphamide results in increased expression of ZFP622 mRNA CTD PMID:27281708 NCBI chr15:25,984,452...25,998,568
Ensembl chr15:25,984,452...25,998,567 		JBrowse link
G Zfp652 zinc finger protein 652 increases expression ISO Cyclophosphamide results in increased expression of ZFP652 mRNA CTD PMID:27281708 NCBI chr11:95,639,893...95,655,541
Ensembl chr11:95,603,499...95,725,941 		JBrowse link
G Zfp655 zinc finger protein 655 decreases expression ISO Cyclophosphamide results in decreased expression of ZFP655 mRNA CTD PMID:27281708 NCBI chr 5:145,168,503...145,184,116
Ensembl chr 5:145,168,525...145,184,112 		JBrowse link
G Zfp827 zinc finger protein 827 increases expression ISO Cyclophosphamide results in increased expression of ZFP827 mRNA CTD PMID:27281708 NCBI chr 8:79,753,754...79,920,397
Ensembl chr 8:79,755,066...79,920,395 		JBrowse link
G Zfr zinc finger RNA binding protein decreases expression ISO Cyclophosphamide results in decreased expression of ZFR mRNA CTD PMID:27281708 NCBI chr15:12,117,649...12,185,535
Ensembl chr15:12,117,917...12,185,769 		JBrowse link
G Zhx3 zinc fingers and homeoboxes 3 decreases expression ISO Cyclophosphamide results in decreased expression of ZHX3 mRNA CTD PMID:27281708 NCBI chr 2:160,612,367...160,714,910
Ensembl chr 2:160,590,628...160,714,918 		JBrowse link
G Zic1 zinc finger protein of the cerebellum 1 affects response to substance ISO ZIC1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 9:91,240,111...91,250,136
Ensembl chr 9:91,240,111...91,247,863 		JBrowse link
G Zzef1 zinc finger, ZZ-type with EF hand domain 1 increases expression ISO Cyclophosphamide results in increased expression of ZZEF1 mRNA CTD PMID:27281708 NCBI chr11:72,686,976...72,817,946
Ensembl chr11:72,687,052...72,817,946 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22182
    role 22167
      biological role 22166
        xenobiotic 19678
          cyclophosphamide 771
            cyclophosphamide hydrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22182
    subatomic particle 22174
      composite particle 22174
        hadron 22174
          baryon 22174
            nucleon 22174
              atomic nucleus 22174
                atom 22174
                  main group element atom 22108
                    p-block element atom 22108
                      chalcogen 21441
                        oxygen atom 21419
                          oxygen molecular entity 21419
                            hydroxides 20799
                              oxoacid 20118
                                pnictogen oxoacid 13685
                                  phosphorus oxoacid 12723
                                    phosphoric acids 11712
                                      phosphoric acid 11712
                                        phosphoramide 1070
                                          phosphorodiamide 1016
                                            cyclophosphamide 771
                                              cyclophosphamide hydrate 0
paths to the root