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Gene-Chemical Interaction Annotations
Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | RGD:736792 | 6480464 | Dihydrotestosterone results in increased expression of ADCYAP1R1 mRNA | CTD | PMID:17254854 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:2038 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ADCYAP1R1 mRNA | CTD | PMID:21215274 | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of ADCYAP1R1 mRNA | CTD | PMID:18648102 | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with XPA gene mutant form co-treated with TRP53 gene mutant form] affects the expression of ADCYAP1R1 mRNA | CTD | PMID:21715664 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of ADCYAP1R1 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of ADCYAP1R1 mRNA] | CTD | PMID:22228805 | cyclophosphamide | affects expression | ISO | RGD:2038 | 6480464 | Cyclophosphamide affects the expression of ADCYAP1R1 mRNA | CTD | PMID:18563302 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of ADCYAP1R1 mRNA | CTD | PMID:21266533 | ethanol | decreases expression | ISO | RGD:2038 | 6480464 | Ethanol results in decreased expression of ADCYAP1R1 mRNA | CTD | PMID:20655511 | exemestane | increases expression | ISO | RGD:736792 | 6480464 | exemestane results in increased expression of ADCYAP1R1 mRNA | CTD | PMID:17254854 | pirinixic acid | multiple interactions | EXP | | 6480464 | NCF1 protein promotes the reaction [pirinixic acid results in decreased expression of ADCYAP1R1 mRNA] | CTD | PMID:17950772 | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of ADCYAP1R1 mRNA | CTD | PMID:17950772 | pirinixic acid | decreases expression | ISO | RGD:2038 | 6480464 | pirinixic acid results in decreased expression of ADCYAP1R1 mRNA | CTD | PMID:19162173 | tacrine | increases expression | ISO | RGD:2038 | 6480464 | Tacrine results in increased expression of ADCYAP1R1 mRNA | CTD | PMID:12832660 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology Annotations
Molecular Pathway Annotations| External Database Links | |
| KEGG Pathway | Circadian entrainment |
| Insulin secretion | |
| Neuroactive ligand-receptor interaction | |
Phenotype Annotations
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Molecular Pathway Annotations| External Database Links | |
| KEGG Pathway | Circadian entrainment |
| Insulin secretion | |
| Neuroactive ligand-receptor interaction | |
Phenotype Annotations
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References - curated| 1. |
Girard BM, etal., J Mol Neurosci. 2008 Nov;36(1-3):310-20. Epub 2008 Jun 19. |
| 2. |
Kawai J, etal., Nature 2001 Feb 8;409(6821):685-90. |
| 3. |
MGD and Homologene mouse data transfer |
| 4. |
MGD data from the GO Consortium |
| 5. |
MGD IEA |
| 6. |
Nicot A, etal., J Neurosci 2002 Nov 1;22(21):9244-54. |
| 7. |
Okazaki Y, etal., Nature 2002 Dec 5;420(6915):563-73. |
| 8. |
RGD automated import pipeline |
| 9. |
RGD automated import pipeline for gene-chemical interactions |
| 10. |
Riek-Burchardt M, etal., Neuropharmacology. 2010 Jan;58(1):199-207. Epub 2009 Jul 30. |
| 11. |
Spengler D, etal., Nature 1993 Sep 9;365(6442):170-5. |
References - uncurated| PubMed | 10095088 |
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RGD Disease Portals| Adcyap1r1 has been annotated in the following RGD Disease Portals. |
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Comparative Map Data| Adcyap1r1 (Mus musculus) |
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| ADCYAP1R1 (Homo sapiens) |
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| Adcyap1r1 (Rattus norvegicus) |
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Position Markers| AI846590 |
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| PMC315446P1 |
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| Adcyap1r1 |
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QTLs in Region (Mouse Genome Assembly Build 37)| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
Nucleotide Sequences| Nucleotide RefSeqs | NM_001025372 | (Get FASTA) | Search GEO for Microarray Profiles |
| NM_007407 | (Get FASTA) | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AAHY01053449 | (Get FASTA) | Search GEO for Microarray Profiles |
| AAHY01053450 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AC069309 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AI843743 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AK013587 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AK042820 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AK047304 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AK081121 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AK083108 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AK147291 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AK147609 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BC067039 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CA316040 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CA320747 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CH466597 | (Get FASTA) | Search GEO for Microarray Profiles | |
| D45171 | (Get FASTA) | Search GEO for Microarray Profiles | |
| D82935 | (Get FASTA) | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_007407 | |||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | |||||||||||||||||||||||||
| Type: | CODING | |||||||||||||||||||||||||
| Protein Acc Id: | NP_031433 | |||||||||||||||||||||||||
| Peptide Label: | isoform 1 precursor | |||||||||||||||||||||||||
| Position: |
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| RefSeq Acc Id: | NM_001025372 | |||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | |||||||||||||||||||||||||
| Type: | CODING | |||||||||||||||||||||||||
| Protein Acc Id: | NP_001020543 | |||||||||||||||||||||||||
| Peptide Label: | isoform 2 precursor | |||||||||||||||||||||||||
| Position: |
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Protein Sequences| Protein RefSeqs | NP_001020543 | (Get FASTA) |
| NP_031433 | (Get FASTA) | |
| GenBank Protein | AAH67039 | (Get FASTA) |
| BAA08119 | (Get FASTA) | |
| BAA11639 | (Get FASTA) | |
| BAC31372 | (Get FASTA) | |
| BAC33020 | (Get FASTA) | |
| BAC38140 | (Get FASTA) | |
| BAE27825 | (Get FASTA) | |
| BAE28023 | (Get FASTA) | |
| EDK98731 | (Get FASTA) | |
| P70205 | (Get FASTA) |
Promoters| RGD ID: | 6838832 | ||||||||||
| Promoter ID: | MM_KWN:46110 | ||||||||||
| Type: | CpG-Island | ||||||||||
| SO ACC ID: | SO:0000170 | ||||||||||
| Source: | MPROMDB | ||||||||||
| Tissues & Cell Lines: | Brain | ||||||||||
| Transcripts: | NM_001025372, NM_007407 | ||||||||||
| Position: |
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External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSMUSG00000029778 | ENTREZGENE |
| Ensembl Protein | ENSMUSP00000066902 | ENTREZGENE |
| Ensembl Transcript | ENSMUST00000070756 | ENTREZGENE |
| Entrez Gene | 11517 | ENTREZGENE |
| Germonline | ENSMUSG00000029778 | |
| HomoloGene Group ID | 870 | ENTREZGENE |
| InterPro | GPCR_2-like | UniProtKB/Swiss-Prot |
| GPCR_2_extracellular_dom | UniProtKB/Swiss-Prot | |
| GPCR_2_PACAP_1_rcpt | UniProtKB/Swiss-Prot | |
| GPCR_2_secretin-like | UniProtKB/Swiss-Prot | |
| GPCR_2_secretin-like_CS | UniProtKB/Swiss-Prot | |
| KEGG Report | mmu:11517 | ENTREZGENE, UniProtKB/Swiss-Prot |
| MGD | MGI:108449 | ENTREZGENE |
| PANTHER | PAC_1_rcpt | UniProtKB/Swiss-Prot |
| Pfam | 7tm_2 | UniProtKB/Swiss-Prot |
| HRM | UniProtKB/Swiss-Prot | |
| PRINTS | GPCRSECRETIN | UniProtKB/Swiss-Prot |
| PACAPRECEPTR | UniProtKB/Swiss-Prot | |
| PROSITE | G_PROTEIN_RECEP_F2_1 | UniProtKB/Swiss-Prot |
| G_PROTEIN_RECEP_F2_2 | UniProtKB/Swiss-Prot | |
| G_PROTEIN_RECEP_F2_3 | UniProtKB/Swiss-Prot | |
| G_PROTEIN_RECEP_F2_4 | UniProtKB/Swiss-Prot | |
| SMART | HormR | UniProtKB/Swiss-Prot |
| UniGene | Mm.44245 | ENTREZGENE |
| UniProt | E9PVE8_MOUSE | UniProtKB/TrEMBL |
| E9Q3E8_MOUSE | UniProtKB/TrEMBL | |
| E9Q4B3_MOUSE | UniProtKB/TrEMBL | |
| E9Q968_MOUSE | UniProtKB/TrEMBL | |
| E9QAL0_MOUSE | UniProtKB/TrEMBL | |
| PACR_MOUSE | UniProtKB/Swiss-Prot | |
| Q6NXJ9_MOUSE | UniProtKB/TrEMBL | |
| Q8BGA4_MOUSE | UniProtKB/TrEMBL | |
| Q8BLT3_MOUSE | UniProtKB/TrEMBL |
| More on Adcyap1r1 | |
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Entrez Gene |
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Ensembl Gene |
![]() | Genome Browser |
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MGI Report |
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NCBI Map Viewer |
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Vista |
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Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 10085 |
| Created: | 2000-05-25 |
| Species: | Mus musculus |
| Last Modified: | 2013-05-14 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.




