Was (Wiskott-Aldrich syndrome) - Rat Genome Database

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Gene: Was (Wiskott-Aldrich syndrome) Mus musculus
Analyze
Symbol: Was
Name: Wiskott-Aldrich syndrome
RGD ID: 1558289
MGI Page MGI
Description: Enables identical protein binding activity. Acts upstream of or within several processes, including actin filament polymerization; cellular response to type II interferon; and endosomal transport. Located in cell-cell junction; phagocytic vesicle; and vesicle membrane. Is expressed in brain; heart; liver; and spleen. Used to study IgA glomerulonephritis and Wiskott-Aldrich syndrome. Human ortholog(s) of this gene implicated in Wiskott-Aldrich syndrome; X-linked severe congenital neutropenia; and thrombocytopenia. Orthologous to human WAS (WASP actin nucleation promoting factor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: actin nucleation-promoting factor WAS; U42471; W; Wasp; Wiskott-Aldrich syndrome homolog; Wiskott-Aldrich syndrome homolog (human); wiskott-Aldrich syndrome protein homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X7,947,705 - 7,956,730 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX7,947,692 - 7,956,737 (-)EnsemblGRCm39 Ensembl
GRCm38X8,081,466 - 8,090,491 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX8,081,453 - 8,090,498 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X7,658,592 - 7,667,617 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X7,238,425 - 7,247,411 (-)NCBIMGSCv36mm8
CeleraX3,379,544 - 3,417,982 (+)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX3.65NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal B cell number  (IAGP)
abnormal B cell physiology  (IAGP)
abnormal B cell proliferation  (IAGP)
abnormal bone marrow cell morphology/development  (IAGP)
abnormal cell migration  (IAGP)
abnormal crypts of Lieberkuhn morphology  (IAGP)
abnormal cytokine secretion  (IAGP)
abnormal dendritic cell antigen presentation  (IAGP)
abnormal dendritic cell morphology  (IAGP)
abnormal dendritic cell physiology  (IAGP)
abnormal double-negative T cell morphology  (IAGP)
abnormal double-positive T cell morphology  (IAGP)
abnormal glomerular mesangium morphology  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal lymphocyte morphology  (IAGP)
abnormal mast cell morphology  (IAGP)
abnormal mast cell physiology  (IAGP)
abnormal megakaryocyte morphology  (IAGP)
abnormal osteoclast differentiation  (IAGP)
abnormal osteoclast physiology  (IAGP)
abnormal renal corpuscle morphology  (IAGP)
abnormal T cell physiology  (IAGP)
abnormal thymocyte activation  (IAGP)
colitis  (IAGP)
crypts of Lieberkuhn abscesses  (IAGP)
decreased B cell number  (IAGP)
decreased double-positive T cell number  (IAGP)
decreased follicular B cell number  (IAGP)
decreased lymphocyte cell number  (IAGP)
decreased marginal zone B cell number  (IAGP)
decreased mature B cell number  (IAGP)
decreased NK cell number  (IAGP)
decreased regulatory T cell number  (IAGP)
decreased single-positive T cell number  (IAGP)
decreased T cell number  (IAGP)
decreased T cell proliferation  (IAGP)
decreased thymocyte number  (IAGP)
expanded mesangial matrix  (IAGP)
glomerulonephritis  (IAGP)
increased anti-chromatin antibody level  (IAGP)
increased anti-double stranded DNA antibody level  (IAGP)
increased anti-single stranded DNA antibody level  (IAGP)
increased autoantibody level  (IAGP)
increased B cell number  (IAGP)
increased follicular B cell number  (IAGP)
increased germinal center B cell number  (IAGP)
increased IgA level  (IAGP)
increased IgE level  (IAGP)
increased IgM level  (IAGP)
increased leukocyte cell number  (IAGP)
increased mesangial cell number  (IAGP)
increased monocyte cell number  (IAGP)
increased neutrophil cell number  (IAGP)
increased plasma cell number  (IAGP)
increased single-positive T cell number  (IAGP)
increased splenocyte number  (IAGP)
increased urine protein level  (IAGP)
lymphoid hypoplasia  (IAGP)
renal glomerular immunoglobulin deposits  (IAGP)
spleen hyperplasia  (IAGP)
thrombocytopenia  (IAGP)
thymus hypoplasia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Wiskott-Aldrich syndrome protein is needed for vaccinia virus pathogenesis. null
2. Isolation of a novel gene mutated in Wiskott-Aldrich syndrome. Derry JM, etal., Cell. 1994 Aug 26;78(4):635-44.
3. Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiency. Lang PA, etal., J Allergy Clin Immunol. 2013 Mar;131(3):815-24. doi: 10.1016/j.jaci.2012.08.050. Epub 2012 Nov 6.
4. Wiskott-Aldrich syndrome protein may be critical for CD8+ T cell function following MCMV infection. Li S, etal., Cell Immunol. 2019 Apr;338:43-50. doi: 10.1016/j.cellimm.2019.03.004. Epub 2019 Mar 27.
5. A transcript map of a 2-Mb BAC contig in the proximal portion of the mouse X chromosome and regional mapping of the scurfy mutation. Means GD, etal., Genomics 2000 May 1;65(3):213-23.
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. MGD IEA MGD IEA
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8666397   PMID:8910519   PMID:8938429   PMID:9488710   PMID:9697838   PMID:10544204   PMID:10922068   PMID:10967094   PMID:11070165   PMID:11493455   PMID:11584271   PMID:11842211  
PMID:11911819   PMID:12147689   PMID:12200375   PMID:12213210   PMID:12466851   PMID:12730112   PMID:12807484   PMID:12855574   PMID:13678593   PMID:14610273   PMID:14645152   PMID:14707117  
PMID:14726392   PMID:15102471   PMID:15130947   PMID:15169891   PMID:15240657   PMID:15265894   PMID:15284122   PMID:15332112   PMID:15361067   PMID:15383456   PMID:15494425   PMID:15699074  
PMID:15774550   PMID:15781335   PMID:16006560   PMID:16141072   PMID:16141245   PMID:16180250   PMID:16302976   PMID:16522820   PMID:16525419   PMID:16602821   PMID:16723544   PMID:16849480  
PMID:16901726   PMID:17141616   PMID:17182853   PMID:17213309   PMID:17218989   PMID:17242350   PMID:17283076   PMID:17296785   PMID:17296786   PMID:17500055   PMID:17512410   PMID:17512803  
PMID:17673604   PMID:17698982   PMID:17764675   PMID:17878299   PMID:17890224   PMID:18043243   PMID:18289379   PMID:18346836   PMID:18446227   PMID:18462674   PMID:18606666   PMID:18650809  
PMID:18687984   PMID:18772454   PMID:19144319   PMID:19234535   PMID:19265163   PMID:19307326   PMID:19359486   PMID:19494259   PMID:19643989   PMID:19692704   PMID:19733207   PMID:19741094  
PMID:19805221   PMID:19808890   PMID:19863535   PMID:20032499   PMID:20071778   PMID:20150425   PMID:20354175   PMID:20457871   PMID:20472831   PMID:20513746   PMID:20599953   PMID:20647543  
PMID:21076065   PMID:21398607   PMID:21515824   PMID:21622861   PMID:21690559   PMID:21705469   PMID:21725061   PMID:21873635   PMID:21875954   PMID:21930784   PMID:22079330   PMID:22253930  
PMID:22279563   PMID:22302739   PMID:22411869   PMID:22431569   PMID:22634306   PMID:22710191   PMID:22932798   PMID:23160469   PMID:23305739   PMID:23337808   PMID:23437151   PMID:23445877  
PMID:23495010   PMID:23684068   PMID:23727585   PMID:23793062   PMID:23820270   PMID:23881916   PMID:24133214   PMID:24223520   PMID:24338698   PMID:24466296   PMID:24482227   PMID:24792912  
PMID:24945741   PMID:25187265   PMID:25213142   PMID:25728049   PMID:25758716   PMID:26028144   PMID:26256668   PMID:26448644   PMID:26468226   PMID:26590149   PMID:26777396   PMID:27069113  
PMID:27143109   PMID:27425374   PMID:27477778   PMID:27599296   PMID:27643438   PMID:28183734   PMID:28600891   PMID:29078804   PMID:29146903   PMID:29150539   PMID:29725003   PMID:30124469  
PMID:30196744   PMID:31219639   PMID:31608063   PMID:31636237   PMID:31916311   PMID:32045478   PMID:32196488   PMID:32492429   PMID:32579434   PMID:32720892   PMID:32721945   PMID:33188196  
PMID:34195186   PMID:34384840   PMID:34431547   PMID:35116029   PMID:35263577   PMID:37944382  


Genomics

Comparative Map Data
Was
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X7,947,705 - 7,956,730 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX7,947,692 - 7,956,737 (-)EnsemblGRCm39 Ensembl
GRCm38X8,081,466 - 8,090,491 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX8,081,453 - 8,090,498 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X7,658,592 - 7,667,617 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X7,238,425 - 7,247,411 (-)NCBIMGSCv36mm8
CeleraX3,379,544 - 3,417,982 (+)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX3.65NCBI
WAS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X48,676,636 - 48,691,427 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX48,676,596 - 48,691,431 (+)EnsemblGRCh38hg38GRCh38
GRCh37X48,542,188 - 48,549,818 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,427,153 - 48,434,759 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X48,298,458 - 48,306,065NCBI
CeleraX53,114,189 - 53,121,821 (-)NCBICelera
Cytogenetic MapXp11.23NCBI
HuRefX46,204,599 - 46,212,234 (+)NCBIHuRef
CHM1_1X48,573,355 - 48,580,986 (+)NCBICHM1_1
T2T-CHM13v2.0X48,087,208 - 48,101,908 (+)NCBIT2T-CHM13v2.0
Was
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X17,077,057 - 17,085,802 (+)NCBIGRCr8
mRatBN7.2X14,405,105 - 14,413,850 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX14,405,124 - 14,413,849 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX19,218,272 - 19,227,021 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X20,856,066 - 20,864,815 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X17,121,250 - 17,129,999 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X15,155,246 - 15,164,099 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,155,230 - 15,164,105 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X15,938,008 - 15,946,861 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X26,436,292 - 26,444,997 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX14,489,816 - 14,498,509 (+)NCBICelera
Cytogenetic MapXq12NCBI
Was
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955543247,631 - 253,274 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955543243,618 - 253,489 (+)NCBIChiLan1.0ChiLan1.0
WAS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X50,172,272 - 50,180,380 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X50,175,644 - 50,183,739 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X40,982,132 - 40,989,767 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X48,842,765 - 48,850,380 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX48,842,765 - 48,850,380 (+)Ensemblpanpan1.1panPan2
WAS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X41,882,240 - 41,890,053 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX41,882,875 - 41,890,058 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX16,258,631 - 16,265,849 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X50,188,660 - 50,195,882 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX50,188,655 - 50,195,835 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X42,005,431 - 42,012,647 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X41,993,869 - 42,001,084 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X42,087,592 - 42,094,803 (+)NCBIUU_Cfam_GSD_1.0
Was
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X34,393,603 - 34,400,920 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936721634,706 - 641,082 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936721634,685 - 641,248 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WAS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX42,774,588 - 42,793,055 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X42,774,597 - 42,793,055 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Pig CytomapXp13NCBI
WAS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X45,809,418 - 45,817,165 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX45,809,189 - 45,817,667 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607611,287,564 - 11,295,694 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Was
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624893487,396 - 493,482 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624893453,793 - 493,696 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Was
269 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:404
Count of miRNA genes:306
Interacting mature miRNAs:346
Transcripts:ENSMUST00000033505, ENSMUST00000146029
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302195Pbwg10_mpostnatal body weight growth 10 (mouse)Not determinedX126202173Mouse
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse

Markers in Region
U42471  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X8,081,830 - 8,081,914UniSTSGRCm38
MGSCv37X7,658,956 - 7,659,040UniSTSGRCm37
Celera1119,252,637 - 19,252,721UniSTS
Cytogenetic MapXA1.1UniSTS
Whitehead/MRC_RH11165.54UniSTS
RH125373  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X8,062,252 - 8,062,475UniSTSGRCm38
MGSCv37X7,639,378 - 7,639,601UniSTSGRCm37
CeleraX3,407,123 - 3,407,346UniSTS
Cytogenetic MapXA1-A2UniSTS
Cytogenetic MapXA1.1UniSTS
AI852103  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X8,061,723 - 8,061,827UniSTSGRCm38
MGSCv37X7,638,849 - 7,638,953UniSTSGRCm37
CeleraX3,407,771 - 3,407,875UniSTS
Cytogenetic MapXA1-A2UniSTS
Cytogenetic MapXA1.1UniSTS
DXS7466E  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X8,061,492 - 8,061,640UniSTSGRCm38
MGSCv37X7,638,618 - 7,638,766UniSTSGRCm37
CeleraX3,407,958 - 3,408,106UniSTS
Cytogenetic MapXA1-A2UniSTS
Cytogenetic MapXA1.1UniSTS
Suv39h1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X8,070,497 - 8,070,669UniSTSGRCm38
MGSCv37X7,647,623 - 7,647,795UniSTSGRCm37
CeleraX3,398,929 - 3,399,101UniSTS
Cytogenetic MapXA1.1UniSTS
Cytogenetic MapXA1-A2UniSTS
cM MapX1.95UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000033505   ⟹   ENSMUSP00000033505
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX7,947,692 - 7,956,737 (-)Ensembl
GRCm38.p6 EnsemblX8,081,453 - 8,090,498 (-)Ensembl
RefSeq Acc Id: ENSMUST00000146029
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX7,952,510 - 7,955,004 (-)Ensembl
GRCm38.p6 EnsemblX8,086,271 - 8,088,765 (-)Ensembl
RefSeq Acc Id: NM_009515   ⟹   NP_033541
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X7,947,705 - 7,956,730 (-)NCBI
GRCm38X8,081,466 - 8,090,491 (-)ENTREZGENE
MGSCv37X7,658,592 - 7,667,617 (-)RGD
CeleraX3,379,544 - 3,417,982 (+)RGD
cM MapX ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_033541 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA85515 (Get FASTA)   NCBI Sequence Viewer  
  AAC52556 (Get FASTA)   NCBI Sequence Viewer  
  AAC99855 (Get FASTA)   NCBI Sequence Viewer  
  EDL33946 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000033505
  ENSMUSP00000033505.7
GenBank Protein P70315 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_033541   ⟸   NM_009515
- UniProtKB: P70315 (UniProtKB/Swiss-Prot),   Q53WY0 (UniProtKB/TrEMBL),   Q61078 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000033505   ⟸   ENSMUST00000033505
Protein Domains
CRIB   WH1   WH2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70315-F1-model_v2 AlphaFold P70315 1-520 view protein structure

Promoters
RGD ID:6846507
Promoter ID:MM_KWN:59475
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour
Transcripts:OTTMUST00000043684
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X7,665,776 - 7,666,472 (-)MPROMDB
RGD ID:6846508
Promoter ID:MM_KWN:59476
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Spleen
Transcripts:NM_009515_WAS,   OTTMUST00000043683
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X7,667,314 - 7,667,814 (-)MPROMDB
RGD ID:13680030
Promoter ID:EPDNEW_M24164
Type:initiation region
Name:Was_1
Description:Mus musculus Wiskott-Aldrich syndrome , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X8,090,464 - 8,090,524EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:105059 AgrOrtholog
Ensembl Genes ENSMUSG00000031165 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000033505 ENTREZGENE
  ENSMUST00000033505.7 UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.810.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CRIB_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CRIB_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WASP_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WASPfam_EVH1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH1/EVH1_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:22376 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:105059 ENTREZGENE
NCBI Gene 22376 ENTREZGENE
Pfam PBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Was PhenoGen
PROSITE CRIB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47912 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt P70315 ENTREZGENE
  Q53WY0 ENTREZGENE, UniProtKB/TrEMBL
  Q61078 ENTREZGENE, UniProtKB/TrEMBL
  WASP_MOUSE UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-21 Was  Wiskott-Aldrich syndrome    Wiskott-Aldrich syndrome homolog (human)  Symbol and/or name change 5135510 APPROVED