Gene: Ctsd (cathepsin D)  Mus musculus Symbol: Ctsd Name: cathepsin D Description: ENCODES a protein that exhibits aspartic-type endopeptidase activity; peptidase activity; endopeptidase activity (ortholog); INVOLVED IN autophagic vacuole assembly; metabolic process; proteolysis (ortholog); PARTICIPATES IN autophagy pathway; ceramide signaling pathway; Mycobacterium tuberculosis infection pathway; ASSOCIATED WITH abnormal antigen presentation; abnormal apoptosis; abnormal crypts of Lieberkuhn morphology; ASSOCIATED WITH Atherosclerosis; Alzheimer Disease (ortholog); Ceroid Lipofuscinosis, Neuronal, 10 (ortholog); FOUND IN lysosome; mitochondrion; extracellular space (ortholog); INTERACTS WITH (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol Type: protein-coding RefSeq Status: PROVISIONAL Also known as: CatD; cathepsin D; CD; OTTMUSP00000020357; OTTMUSP00000037478 Orthologs: Homo sapiens : CTSD (cathepsin D)  HGNC Rattus norvegicus : Ctsd (cathepsin D) Latest Assembly: Mouse Genome Assembly Build 37 Position: Map Chr Position Strand Source Mouse Genome Assembly GRCm38 7 142,375,916 - 142,387,870 - NCBI Mouse cM Map 7   - NCBI Mouse Celera Assembly 7 142,131,673 - 142,143,627 - NCBI Mouse Genome Assembly Build 37 7 149,561,821 - 149,573,775 - NCBI Mouse Genome Assembly Build 36.1 7 149,561,821 - 149,573,775 - NCBI Mouse Cytogenetic Map 7 F5   NCBI Model Launch Genome Browser (GBrowse) Annotation    (Toggle Detail/Summary View) Disease Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) Alzheimer Disease   ISS   1358532   RGD   Atherosclerosis   IGI RGD:733604 5687152   RGD   Ceroid Lipofuscinosis, Neuronal, 10   ISS RGD:1351014 7240710   OMIM   Gene-Chemical Interaction Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) (+)-alpha-tocopherol increases expression ISO RGD:621511 6480464 alpha-Tocopherol results in increased expression of CTSD protein CTD PMID:18942769 (+)-pilocarpine increases expression ISO RGD:621511 6480464 Pilocarpine results in increased expression of CTSD mRNA CTD PMID:17971868 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:621511 6480464 epigallocatechin gallate inhibits the reaction [Isoproterenol affects the activity of CTSD protein] CTD PMID:18294627 (R)-lipoic acid multiple interactions ISO RGD:621511 6480464 Thioctic Acid inhibits the reaction [Doxorubicin results in decreased activity of CTSD protein] CTD PMID:12841641 (S)-amphetamine decreases expression EXP   6480464 Dextroamphetamine results in decreased expression of CTSD mRNA CTD PMID:12558987 1,2,4-trimethylbenzene decreases expression ISO RGD:621511 6480464 pseudocumene results in decreased expression of CTSD protein CTD PMID:17337753 17beta-estradiol increases secretion ISO RGD:1351014 6480464 Estradiol results in increased secretion of CTSD protein CTD PMID:2278856 more ... 17beta-estradiol increases secretion ISO RGD:1351014 6480464 Estradiol results in increased secretion of CTSD protein CTD PMID:2278856 more ... 17beta-estradiol increases expression ISO RGD:1351014 6480464 Estradiol results in increased expression of CTSD mRNA CTD PMID:10411295 more ... 17beta-estradiol multiple interactions ISO RGD:1351014 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased secretion of CTSD protein CTD PMID:7909315 17beta-estradiol increases secretion ISO RGD:1351014 6480464 Estradiol results in increased secretion of CTSD protein CTD PMID:2278856 more ... 17beta-estradiol multiple interactions ISO RGD:1351014 6480464 [Estradiol results in increased activity of ESR1 protein] which results in increased expression of CTSD mRNA CTD PMID:22403704 17beta-estradiol increases expression ISO RGD:1351014 6480464 Estradiol results in increased expression of CTSD mRNA CTD PMID:10411295 more ... 17beta-estradiol multiple interactions ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CTSD mRNA] CTD PMID:11165043 more ... 17beta-estradiol increases expression ISO RGD:1351014 6480464 Estradiol results in increased expression of CTSD protein CTD PMID:22235307 17beta-estradiol multiple interactions ISO RGD:1351014 6480464 3',4'-dimethoxy-alpha-naphthoflavone inhibits the reaction [Estradiol results in increased expression of CTSD mRNA]; more ... CTD PMID:22235307 17beta-estradiol multiple interactions ISO RGD:1351014 6480464 fulvestrant inhibits the reaction [Estradiol results in increased expression of CTSD mRNA] CTD PMID:19365803 PMID:19654927 17beta-estradiol increases expression ISO RGD:1351014 6480464 Estradiol results in increased expression of CTSD mRNA CTD PMID:10411295 more ... 17beta-estradiol increases expression ISO RGD:1351014 6480464 Estradiol results in increased expression of CTSD mRNA CTD PMID:10411295 more ... 17beta-estradiol increases expression ISO RGD:1351014 6480464 Estradiol results in increased expression of CTSD mRNA CTD PMID:19654927 more ... 17beta-estradiol multiple interactions ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CTSD mRNA] CTD PMID:11179685 PMID:11165043 17beta-estradiol increases expression ISO RGD:1351014 6480464 Estradiol results in increased expression of CTSD mRNA CTD PMID:15090535 more ... 17beta-estradiol increases secretion ISO RGD:1351014 6480464 Estradiol results in increased secretion of CTSD protein CTD PMID:8384872 PMID:2278856 17beta-estradiol increases expression ISO RGD:1351014 6480464 Estradiol results in increased expression of CTSD mRNA CTD PMID:11179685 more ... 17beta-estradiol multiple interactions ISO RGD:1351014 6480464 Estradiol promotes the reaction [[ESR1 protein binds to CTSD promoter] which results in increased expression of CTSD mRNA] CTD PMID:11165043 PMID:11165043 17beta-estradiol multiple interactions ISO RGD:1351014 6480464 fulvestrant inhibits the reaction [Estradiol results in increased expression of CTSD mRNA] CTD PMID:19654927 17beta-estradiol increases expression ISO RGD:1351014 6480464 Estradiol results in increased expression of CTSD mRNA CTD PMID:19619570 more ... 17beta-estradiol multiple interactions ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased secretion of CTSD protein] CTD PMID:2278856 PMID:8384872 17beta-estradiol increases expression ISO RGD:1351014 6480464 Estradiol results in increased expression of CTSD mRNA CTD PMID:11165043 more ... 17beta-estradiol multiple interactions ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased secretion of CTSD protein modified form] CTD PMID:2278856 17beta-estradiol multiple interactions ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased secretion of CTSD protein] CTD PMID:8384872 PMID:2278856 17beta-estradiol multiple interactions ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CTSD mRNA] CTD PMID:11165043 PMID:11179685 17beta-estradiol increases secretion ISO RGD:1351014 6480464 Estradiol results in increased secretion of CTSD protein modified form CTD PMID:2278856 17beta-estradiol increases expression ISO RGD:1351014 6480464 Estradiol results in increased expression of CTSD mRNA CTD PMID:19619570 more ... 17beta-estradiol increases secretion ISO RGD:1351014 6480464 Estradiol results in increased secretion of CTSD protein CTD PMID:2278856 PMID:8384872 17beta-estradiol multiple interactions ISO RGD:1351014 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of CTSD mRNA CTD PMID:19619570 17beta-estradiol multiple interactions ISO RGD:1351014 6480464 Estradiol promotes the reaction [ESR1 protein binds to CTSD promoter] CTD PMID:19698761 17beta-estradiol multiple interactions ISO RGD:1351014 6480464 alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CTSD mRNA]]; more ... CTD PMID:11165043 17beta-estradiol increases expression ISO RGD:1351014 6480464 Estradiol results in increased expression of CTSD protein CTD PMID:22235307 PMID:8524236 17beta-estradiol increases expression ISO RGD:1351014 6480464 Estradiol results in increased expression of CTSD mRNA CTD PMID:10411295 more ... 17beta-estradiol multiple interactions ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased secretion of CTSD protein] CTD PMID:2278856 more ... 17beta-estradiol multiple interactions ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CTSD protein] CTD PMID:22235307 PMID:8524236 17beta-estradiol multiple interactions ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CTSD mRNA] CTD PMID:11165043 more ... 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one decreases expression ISO RGD:1351014 6480464 Metribolone results in decreased expression of CTSD protein CTD PMID:17152098 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased secretion of CTSD protein modified form] CTD PMID:2278856 2,3,7,8-tetrachlorodibenzodioxine increases secretion ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin results in increased secretion of CTSD protein CTD PMID:7909315 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1351014 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased secretion of CTSD protein CTD PMID:7909315 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CTSD mRNA] CTD PMID:11165043 more ... 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CTSD protein] CTD PMID:22235307 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP   6480464 Tetrachlorodibenzodioxin affects the expression of CTSD mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CTSD protein] CTD PMID:22235307 PMID:8524236 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CTSD mRNA] CTD PMID:11165043 more ... 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased secretion of CTSD protein] CTD PMID:2278856 more ... 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased secretion of CTSD protein] CTD PMID:2278856 PMID:8384872 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CTSD mRNA] CTD PMID:11165043 PMID:11179685 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased secretion of CTSD protein] CTD PMID:8384872 PMID:2278856 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CTSD mRNA] CTD PMID:11179685 PMID:11165043 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1351014 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of CTSD mRNA CTD PMID:19619570 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1351014 6480464 alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CTSD mRNA]]; more ... CTD PMID:11165043 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP   6480464 Tetrachlorodibenzodioxin results in increased expression of CTSD mRNA CTD PMID:11879969 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1351014 6480464 Tetrachlorodibenzodioxin results in decreased expression of CTSD mRNA CTD PMID:19619570 2-amino-2-deoxy-D-glucopyranose affects localization ISO RGD:1351014 6480464 Glucosamine affects the localization of CTSD protein CTD PMID:15972124 2-amino-2-deoxy-D-glucopyranose increases activity ISO RGD:1351014 6480464 Glucosamine results in increased activity of CTSD protein CTD PMID:16850161 2-amino-2-deoxy-D-glucopyranose decreases expression ISO RGD:1351014 6480464 Glucosamine results in decreased expression of CTSD protein alternative form CTD PMID:16850161 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO RGD:1351014 6480464 pepstatin inhibits the reaction [Glucosamine results in decreased expression of CTSD protein alternative form] CTD PMID:16850161 2-butoxyethanol increases expression EXP   6480464 n-butoxyethanol results in increased expression of CTSD mRNA CTD PMID:19812364 2-nitrofluorene increases expression ISO RGD:621511 6480464 2-nitrofluorene results in increased expression of CTSD mRNA CTD PMID:15890375 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine increases activity ISO RGD:621511 6480464 Puromycin Aminonucleoside results in increased activity of CTSD protein CTD PMID:6497855 3,4-methylenedioxymethamphetamine increases expression EXP   6480464 N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of CTSD mRNA CTD PMID:20188158 3-methylcholanthrene increases expression ISO RGD:1351014 6480464 Methylcholanthrene results in increased expression of CTSD mRNA CTD PMID:16257430 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression ISO RGD:621511 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CTSD mRNA CTD PMID:15890375 6alpha-methylprednisolone multiple interactions ISO RGD:621511 6480464 Methylprednisolone inhibits the reaction [Isoproterenol results in increased expression of CTSD mRNA] CTD PMID:894732 7,12-dimethyltetraphene increases expression ISO RGD:621511 6480464 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CTSD mRNA CTD PMID:12097258 aflatoxin B1 increases expression ISO RGD:621511 6480464 Aflatoxin B1 results in increased expression of CTSD mRNA CTD PMID:15890375 aldehydo-D-glucosamine affects localization ISO RGD:1351014 6480464 Glucosamine affects the localization of CTSD protein CTD PMID:15972124 aldehydo-D-glucosamine increases activity ISO RGD:1351014 6480464 Glucosamine results in increased activity of CTSD protein CTD PMID:16850161 aldehydo-D-glucosamine decreases expression ISO RGD:1351014 6480464 Glucosamine results in decreased expression of CTSD protein alternative form CTD PMID:16850161 aldehydo-D-glucosamine multiple interactions ISO RGD:1351014 6480464 pepstatin inhibits the reaction [Glucosamine results in decreased expression of CTSD protein alternative form] CTD PMID:16850161 all-trans-retinoic acid increases expression ISO RGD:1351014 6480464 Tretinoin results in increased expression of CTSD mRNA CTD PMID:17218384 PMID:16054129 all-trans-retinoic acid increases expression ISO RGD:1351014 6480464 Tretinoin results in increased expression of CTSD mRNA CTD PMID:15498508 more ... all-trans-retinoic acid increases expression ISO RGD:1351014 6480464 Tretinoin results in increased expression of CTSD mRNA CTD PMID:15498508 more ... all-trans-retinoic acid increases expression ISO RGD:1351014 6480464 Tretinoin results in increased expression of CTSD mRNA CTD PMID:17218384 more ... all-trans-retinoic acid increases expression ISO RGD:1351014 6480464 Tretinoin results in increased expression of CTSD mRNA CTD PMID:16054129 more ... amlodipine multiple interactions ISO RGD:621511 6480464 [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:11829124 PMID:14499179 amlodipine multiple interactions ISO RGD:621511 6480464 [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:14499179 PMID:11829124 amlodipine multiple interactions ISO RGD:621511 6480464 [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein] CTD PMID:14499179 ammonium chloride increases expression ISO RGD:621511 6480464 Ammonium Chloride results in increased expression of CTSD protein CTD PMID:16483693 ammonium chloride affects expression ISO RGD:621511 6480464 Ammonium Chloride affects the expression of CTSD mRNA CTD PMID:16483693 benzo[a]pyrene decreases expression ISO RGD:1351014 6480464 Benzo(a)pyrene results in decreased expression of CTSD mRNA CTD PMID:17879257 benzo[a]pyrene multiple interactions ISO RGD:1351014 6480464 fulvestrant inhibits the reaction [Benzo(a)pyrene results in increased expression of CTSD mRNA]; more ... CTD PMID:19365803 benzo[a]pyrene increases expression ISO RGD:1351014 6480464 Benzo(a)pyrene analog results in increased expression of CTSD mRNA; more ... CTD PMID:19365803 benzo[a]pyrene increases expression EXP   6480464 Benzo(a)pyrene results in increased expression of CTSD mRNA CTD PMID:21715664 PMID:22228805 benzo[a]pyrene increases expression EXP   6480464 Benzo(a)pyrene results in increased expression of CTSD mRNA CTD PMID:21715664 beta-D-glucosamine affects localization ISO RGD:1351014 6480464 Glucosamine affects the localization of CTSD protein CTD PMID:15972124 beta-D-glucosamine decreases expression ISO RGD:1351014 6480464 Glucosamine results in decreased expression of CTSD protein alternative form CTD PMID:16850161 beta-D-glucosamine multiple interactions ISO RGD:1351014 6480464 pepstatin inhibits the reaction [Glucosamine results in decreased expression of CTSD protein alternative form] CTD PMID:16850161 beta-D-glucosamine increases activity ISO RGD:1351014 6480464 Glucosamine results in increased activity of CTSD protein CTD PMID:16850161 bisphenol A multiple interactions ISO RGD:1351014 6480464 [bisphenol A results in increased activity of ESR1 protein] which results in increased expression of CTSD mRNA CTD PMID:14754635 bisphenol A multiple interactions ISO RGD:1351014 6480464 [bisphenol A results in increased activity of ESR1 protein] which results in increased expression of CTSD mRNA CTD PMID:14754635 PMID:22403704 cadmium dichloride increases expression ISO RGD:1351014 6480464 Cadmium Chloride results in increased expression of CTSD CTD PMID:22041583 cadmium dichloride decreases expression ISO RGD:621511 6480464 Cadmium Chloride results in decreased expression of CTSD mRNA CTD PMID:21297351 cadmium dichloride multiple interactions ISO RGD:1351014 6480464 Melatonin inhibits the reaction [Cadmium Chloride results in increased expression of CTSD] CTD PMID:22041583 chloroquine affects localization ISO RGD:621511 6480464 Chloroquine affects the localization of CTSD protein CTD PMID:7715800 chloroquine increases expression ISO RGD:621511 6480464 Chloroquine results in increased expression of CTSD protein CTD PMID:2759144 choline multiple interactions EXP   6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CTSD mRNA CTD PMID:20938992 cimetidine decreases activity ISO RGD:621511 6480464 Cimetidine results in decreased activity of CTSD protein CTD PMID:12903910 cis-caffeic acid multiple interactions ISO RGD:621511 6480464 caffeic acid inhibits the reaction [Isoproterenol affects the activity of CTSD protein] CTD PMID:20391626 cisplatin increases expression EXP   6480464 Cisplatin results in increased expression of CTSD mRNA CTD PMID:21151649 clofibrate decreases expression EXP   6480464 Clofibrate results in decreased expression of CTSD mRNA CTD PMID:17585979 cobalt dichloride increases expression ISO RGD:1351014 6480464 cobaltous chloride results in increased expression of CTSD mRNA CTD PMID:19320972 PMID:19376846 cocaine affects expression EXP   6480464 Cocaine affects the expression of CTSD mRNA CTD PMID:15681117 copper atom multiple interactions ISO RGD:1351014 6480464 [NSC 689534 binds to Copper] which results in increased expression of CTSD mRNA CTD PMID:20971185 copper(0) multiple interactions ISO RGD:1351014 6480464 [NSC 689534 binds to Copper] which results in increased expression of CTSD mRNA CTD PMID:20971185 curcumin multiple interactions ISO RGD:621511 6480464 Curcumin inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein]; more ... CTD PMID:8534267 cyclophosphamide multiple interactions EXP   6480464 [Cyclophosphamide co-treated with Mecamylamine] results in increased expression of CTSD mRNA CTD PMID:18433785 cyclosporin A increases expression ISO RGD:1351014 6480464 Cyclosporine results in increased expression of CTSD mRNA CTD PMID:20106945 cysteamine increases expression ISO RGD:621511 6480464 Cysteamine results in increased expression of CTSD protein CTD PMID:20165931 cysteamine multiple interactions ISO RGD:621511 6480464 thamira parpam inhibits the reaction [Cysteamine results in increased expression of CTSD protein]; more ... CTD PMID:20165931 DDT multiple interactions ISO RGD:1351014 6480464 [DDT results in increased activity of ESR1 protein] which results in increased expression of CTSD mRNA CTD PMID:22403704 Delta(9)-tetrahydrocannabinol increases expression ISO RGD:1351014 6480464 Tetrahydrocannabinol results in increased expression of CTSD protein; more ... CTD PMID:18163980 dexamethasone increases expression EXP   6480464 Dexamethasone results in increased expression of CTSD mRNA CTD PMID:21041162 diazoxide multiple interactions ISO RGD:621511 6480464 alliin affects the reaction [Isoproterenol affects the activity of CTSD protein] CTD PMID:17623887 diazoxide affects activity ISO RGD:621511 6480464 Isoproterenol affects the activity of CTSD protein CTD PMID:17623887 more ... diazoxide multiple interactions ISO RGD:621511 6480464 epigallocatechin gallate inhibits the reaction [Isoproterenol affects the activity of CTSD protein] CTD PMID:18294627 diazoxide affects activity ISO RGD:621511 6480464 Isoproterenol affects the activity of CTSD protein CTD PMID:17623887 PMID:20391626 diazoxide multiple interactions ISO RGD:621511 6480464 caffeic acid inhibits the reaction [Isoproterenol affects the activity of CTSD protein] CTD PMID:20391626 diazoxide increases activity ISO RGD:621511 6480464 Isoproterenol results in increased activity of CTSD protein CTD PMID:11829124 more ... diazoxide increases activity ISO RGD:621511 6480464 Isoproterenol results in increased activity of CTSD protein CTD PMID:17188415 more ... diazoxide decreases activity ISO RGD:621511 6480464 Isoproterenol results in decreased activity of CTSD protein CTD PMID:14499179 more ... diazoxide increases activity ISO RGD:621511 6480464 Isoproterenol results in increased activity of CTSD protein CTD PMID:14499179 more ... diazoxide increases activity ISO RGD:621511 6480464 Isoproterenol results in increased activity of CTSD protein CTD PMID:17188415 more ... diazoxide decreases activity ISO RGD:621511 6480464 Isoproterenol results in decreased activity of CTSD protein CTD PMID:14499179 more ... diazoxide increases activity ISO RGD:621511 6480464 Isoproterenol results in increased activity of CTSD protein CTD PMID:21762681 more ... diazoxide decreases activity ISO RGD:621511 6480464 Isoproterenol results in decreased activity of CTSD protein CTD PMID:19172585 more ... diazoxide multiple interactions ISO RGD:621511 6480464 [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:11829124 PMID:14499179 diazoxide increases activity ISO RGD:621511 6480464 Isoproterenol results in increased activity of CTSD protein CTD PMID:19641666 more ... diazoxide increases expression ISO RGD:621511 6480464 Isoproterenol results in increased expression of CTSD mRNA CTD PMID:17182065 PMID:894732 diazoxide decreases activity ISO RGD:621511 6480464 Isoproterenol results in decreased activity of CTSD protein CTD PMID:8534267 more ... diazoxide multiple interactions ISO RGD:621511 6480464 Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:21762681 diazoxide multiple interactions ISO RGD:621511 6480464 S-allylcysteine inhibits the reaction [Isoproterenol results in increased expression of CTSD mRNA] CTD PMID:17182065 diazoxide multiple interactions ISO RGD:621511 6480464 Plant Extracts inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:19641666 diazoxide multiple interactions ISO RGD:621511 6480464 [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:14499179 PMID:11829124 diazoxide multiple interactions ISO RGD:621511 6480464 [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein] CTD PMID:14499179 diazoxide multiple interactions ISO RGD:621511 6480464 naringin inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:17188415 diazoxide multiple interactions ISO RGD:621511 6480464 Methylprednisolone inhibits the reaction [Isoproterenol results in increased expression of CTSD mRNA] CTD PMID:894732 diazoxide multiple interactions ISO RGD:621511 6480464 mangiferin inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein] CTD PMID:19172585 diazoxide increases expression ISO RGD:621511 6480464 Isoproterenol results in increased expression of CTSD protein CTD PMID:18424012 diazoxide increases expression ISO RGD:621511 6480464 Isoproterenol results in increased expression of CTSD mRNA CTD PMID:894732 PMID:17182065 diazoxide increases activity ISO RGD:621511 6480464 Isoproterenol results in increased activity of CTSD protein CTD PMID:8534267 more ... diazoxide decreases activity ISO RGD:621511 6480464 Isoproterenol results in decreased activity of CTSD protein CTD PMID:8534267 more ... diazoxide affects activity ISO RGD:621511 6480464 Isoproterenol affects the activity of CTSD protein CTD PMID:17623887 diazoxide multiple interactions ISO RGD:621511 6480464 [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:17045618 diazoxide multiple interactions ISO RGD:621511 6480464 Curcumin inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein]; more ... CTD PMID:8534267 dibutyl phthalate decreases expression ISO RGD:621511 6480464 Dibutyl Phthalate results in decreased expression of CTSD mRNA CTD PMID:17379624 diethylstilbestrol increases expression ISO RGD:621511 6480464 Diethylstilbestrol results in increased expression of CTSD mRNA CTD PMID:15890375 disodium cromoglycate multiple interactions EXP   6480464 [pristane co-treated with Cromolyn Sodium] results in increased expression of CTSD protein CTD PMID:8812242 diuron decreases expression ISO RGD:621511 6480464 Diuron results in decreased expression of CTSD mRNA CTD PMID:21551480 doxorubicin decreases response to substance ISO RGD:1351014 6480464 CTSD protein results in decreased susceptibility to Doxorubicin CTD PMID:18566016 doxorubicin decreases activity ISO RGD:621511 6480464 Doxorubicin results in decreased activity of CTSD protein CTD PMID:12841641 doxorubicin multiple interactions ISO RGD:621511 6480464 Thioctic Acid inhibits the reaction [Doxorubicin results in decreased activity of CTSD protein] CTD PMID:12841641 doxorubicin decreases expression ISO RGD:621511 6480464 Doxorubicin results in decreased expression of CTSD mRNA CTD PMID:19915844 doxorubicin increases expression ISO RGD:1351014 6480464 Doxorubicin results in increased expression of CTSD protein CTD PMID:18566016 ellagic acid multiple interactions ISO RGD:621511 6480464 Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:21762681 emodin decreases expression ISO RGD:1351014 6480464 Emodin results in decreased expression of CTSD mRNA CTD PMID:16045814 ethambutol multiple interactions ISO RGD:621511 6480464 Ethambutol results in increased expression of and affects the localization of CTSD protein; more ... CTD PMID:19063910 ferulic acid multiple interactions ISO RGD:621511 6480464 [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:17045618 folic acid multiple interactions EXP   6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CTSD mRNA CTD PMID:20938992 fulvestrant increases expression ISO RGD:1351014 6480464 fulvestrant results in increased expression of CTSD mRNA CTD PMID:15072547 fulvestrant decreases expression ISO RGD:1351014 6480464 fulvestrant results in decreased expression of CTSD mRNA CTD PMID:14750165 fulvestrant multiple interactions ISO RGD:1351014 6480464 fulvestrant inhibits the reaction [Estradiol results in increased expression of CTSD mRNA] CTD PMID:19365803 PMID:19654927 fulvestrant multiple interactions ISO RGD:1351014 6480464 fulvestrant inhibits the reaction [Benzo(a)pyrene analog results in increased expression of CTSD mRNA]; more ... CTD PMID:19365803 fulvestrant multiple interactions ISO RGD:1351014 6480464 fulvestrant inhibits the reaction [1,7-diphenyl-5-heptene-3-one results in increased expression of CTSD mRNA]; more ... CTD PMID:19654927 fumonisin B1 increases expression EXP   6480464 fumonisin B1 results in increased expression of CTSD mRNA CTD PMID:16221962 genistein increases expression ISO RGD:1351014 6480464 Genistein results in increased expression of CTSD mRNA CTD PMID:15090535 genistein decreases expression EXP   6480464 Genistein results in decreased expression of CTSD mRNA CTD PMID:21048042 hydrogen peroxide affects expression ISO RGD:1351014 6480464 Hydrogen Peroxide affects the expression of CTSD protein CTD PMID:21179406 indole-3-methanol decreases expression ISO RGD:1351014 6480464 indole-3-carbinol results in decreased expression of CTSD protein CTD PMID:11110848 isoprenaline multiple interactions ISO RGD:621511 6480464 alliin affects the reaction [Isoproterenol affects the activity of CTSD protein] CTD PMID:17623887 isoprenaline affects activity ISO RGD:621511 6480464 Isoproterenol affects the activity of CTSD protein CTD PMID:17623887 more ... isoprenaline multiple interactions ISO RGD:621511 6480464 epigallocatechin gallate inhibits the reaction [Isoproterenol affects the activity of CTSD protein] CTD PMID:18294627 isoprenaline affects activity ISO RGD:621511 6480464 Isoproterenol affects the activity of CTSD protein CTD PMID:17623887 PMID:20391626 isoprenaline multiple interactions ISO RGD:621511 6480464 caffeic acid inhibits the reaction [Isoproterenol affects the activity of CTSD protein] CTD PMID:20391626 isoprenaline increases activity ISO RGD:621511 6480464 Isoproterenol results in increased activity of CTSD protein CTD PMID:11829124 more ... isoprenaline increases activity ISO RGD:621511 6480464 Isoproterenol results in increased activity of CTSD protein CTD PMID:17188415 more ... isoprenaline decreases activity ISO RGD:621511 6480464 Isoproterenol results in decreased activity of CTSD protein CTD PMID:14499179 more ... isoprenaline increases activity ISO RGD:621511 6480464 Isoproterenol results in increased activity of CTSD protein CTD PMID:14499179 more ... isoprenaline multiple interactions ISO RGD:621511 6480464 [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:11829124 PMID:14499179 isoprenaline increases expression ISO RGD:621511 6480464 Isoproterenol results in increased expression of CTSD mRNA CTD PMID:17182065 PMID:894732 isoprenaline increases activity ISO RGD:621511 6480464 Isoproterenol results in increased activity of CTSD protein CTD PMID:17188415 more ... isoprenaline decreases activity ISO RGD:621511 6480464 Isoproterenol results in decreased activity of CTSD protein CTD PMID:14499179 more ... isoprenaline multiple interactions ISO RGD:621511 6480464 S-allylcysteine inhibits the reaction [Isoproterenol results in increased expression of CTSD mRNA] CTD PMID:17182065 isoprenaline multiple interactions ISO RGD:621511 6480464 [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:14499179 PMID:11829124 isoprenaline multiple interactions ISO RGD:621511 6480464 Plant Extracts inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:19641666 isoprenaline multiple interactions ISO RGD:621511 6480464 naringin inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:17188415 isoprenaline multiple interactions ISO RGD:621511 6480464 [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein] CTD PMID:14499179 isoprenaline multiple interactions ISO RGD:621511 6480464 Methylprednisolone inhibits the reaction [Isoproterenol results in increased expression of CTSD mRNA] CTD PMID:894732 isoprenaline increases expression ISO RGD:621511 6480464 Isoproterenol results in increased expression of CTSD protein CTD PMID:18424012 isoprenaline multiple interactions ISO RGD:621511 6480464 mangiferin inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein] CTD PMID:19172585 isoprenaline increases expression ISO RGD:621511 6480464 Isoproterenol results in increased expression of CTSD mRNA CTD PMID:894732 PMID:17182065 isoprenaline increases activity ISO RGD:621511 6480464 Isoproterenol results in increased activity of CTSD protein CTD PMID:21762681 more ... isoprenaline decreases activity ISO RGD:621511 6480464 Isoproterenol results in decreased activity of CTSD protein CTD PMID:19172585 more ... isoprenaline affects activity ISO RGD:621511 6480464 Isoproterenol affects the activity of CTSD protein CTD PMID:17623887 isoprenaline multiple interactions ISO RGD:621511 6480464 [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:17045618 isoprenaline multiple interactions ISO RGD:621511 6480464 Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:21762681 isoprenaline multiple interactions ISO RGD:621511 6480464 Curcumin inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein]; more ... CTD PMID:8534267 L-ascorbic acid multiple interactions ISO RGD:621511 6480464 [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:17045618 L-methionine multiple interactions EXP   6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CTSD mRNA CTD PMID:20938992 linalool increases expression ISO RGD:1351014 6480464 linalool results in increased expression of CTSD mRNA CTD PMID:19922762 lipoic acid multiple interactions ISO RGD:621511 6480464 Thioctic Acid inhibits the reaction [Doxorubicin results in decreased activity of CTSD protein] CTD PMID:12841641 lithium atom increases expression ISO RGD:621511 6480464 Lithium results in increased expression of CTSD protein CTD PMID:18296634 lucanthone increases expression ISO RGD:1351014 6480464 Lucanthone results in increased expression of CTSD protein; more ... CTD PMID:21148553 malathion increases expression EXP   6480464 Malathion results in increased expression of CTSD protein CTD PMID:8812242 mangiferin multiple interactions ISO RGD:621511 6480464 mangiferin inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein] CTD PMID:19172585 melatonin multiple interactions ISO RGD:1351014 6480464 Melatonin inhibits the reaction [Cadmium Chloride results in increased expression of CTSD] CTD PMID:22041583 methamphetamine affects localization ISO RGD:621511 6480464 Methamphetamine affects the localization of CTSD protein CTD PMID:17105920 methapyrilene increases expression ISO RGD:621511 6480464 Methapyrilene results in increased expression of CTSD mRNA CTD PMID:15890375 N-nitrosodimethylamine increases expression ISO RGD:621511 6480464 Dimethylnitrosamine results in increased expression of CTSD mRNA CTD PMID:15890375 N-tosyl-L-phenylalanyl chloromethyl ketone increases expression ISO RGD:1351014 6480464 Tosylphenylalanyl Chloromethyl Ketone results in increased expression of CTSD protein CTD PMID:10772776 naringin multiple interactions ISO RGD:621511 6480464 naringin inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:17188415 nitric oxide increases secretion ISO RGD:621511 6480464 Nitric Oxide results in increased secretion of CTSD protein CTD PMID:15040013 nitroglycerin decreases expression ISO RGD:621511 6480464 Nitroglycerin results in decreased expression of CTSD mRNA CTD PMID:12102619 omeprazole multiple interactions ISO RGD:621511 6480464 Omeprazole inhibits the reaction [Cysteamine results in increased expression of CTSD protein] CTD PMID:20165931 paracetamol increases expression EXP   6480464 Acetaminophen results in increased expression of CTSD protein CTD PMID:8794998 paracetamol affects expression EXP   6480464 Acetaminophen affects the expression of CTSD mRNA CTD PMID:17562736 paraquat decreases expression EXP   6480464 Paraquat results in decreased expression of CTSD mRNA CTD PMID:16797015 phenacetin increases expression ISO RGD:621511 6480464 Phenacetin results in increased expression of CTSD mRNA CTD PMID:17698508 phenobarbital increases expression ISO RGD:621511 6480464 Phenobarbital results in increased expression of CTSD mRNA CTD PMID:19162173 phenylhydrazine increases expression ISO RGD:621511 6480464 phenylhydrazine results in increased expression of CTSD mRNA CTD PMID:17698508 piperonyl butoxide increases expression ISO RGD:621511 6480464 Piperonyl Butoxide results in increased expression of CTSD mRNA CTD PMID:15890375 piperonyl butoxide increases expression ISO RGD:621511 6480464 Piperonyl Butoxide results in increased expression of CTSD mRNA CTD PMID:15890375 PMID:22484513 pirimiphos-methyl decreases activity ISO RGD:621511 6480464 pirimiphos methyl results in decreased activity of CTSD protein CTD PMID:9204212 pirimiphos-methyl increases activity ISO RGD:621511 6480464 pirimiphos methyl results in increased activity of CTSD protein CTD PMID:9204212 pirinixic acid increases expression EXP   6480464 pirinixic acid results in increased expression of CTSD mRNA CTD PMID:18301758 PMID:20813756 pirinixic acid increases expression ISO RGD:621511 6480464 pirinixic acid results in increased expression of CTSD mRNA CTD PMID:19162173 PMID:15890375 pirinixic acid increases expression EXP   6480464 pirinixic acid results in increased expression of CTSD mRNA CTD PMID:20813756 PMID:18301758 pirinixic acid increases expression ISO RGD:621511 6480464 pirinixic acid results in increased expression of CTSD mRNA CTD PMID:15890375 PMID:19162173 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:621511 6480464 Pregnenolone Carbonitrile results in increased expression of CTSD mRNA CTD PMID:19162173 pristane increases expression EXP   6480464 pristane results in increased expression of CTSD protein CTD PMID:8812242 pristane multiple interactions EXP   6480464 [pristane co-treated with Cromolyn Sodium] results in increased expression of CTSD protein CTD PMID:8812242 propiconazole increases expression EXP   6480464 propiconazole results in increased expression of CTSD mRNA CTD PMID:22334560 quercetin increases expression ISO RGD:1351014 6480464 Quercetin results in increased expression of CTSD mRNA CTD PMID:15090535 quercetin increases expression ISO RGD:1351014 6480464 Quercetin results in increased expression of CTSD mRNA CTD PMID:15090535 PMID:21632981 resveratrol increases expression ISO RGD:1351014 6480464 resveratrol metabolite results in increased expression of CTSD mRNA CTD PMID:19496085 resveratrol increases expression ISO RGD:1351014 6480464 resveratrol results in increased expression of CTSD mRNA CTD PMID:20878097 resveratrol increases expression ISO RGD:1351014 6480464 resveratrol results in increased expression of CTSD protein CTD PMID:18089832 resveratrol increases expression ISO RGD:1351014 6480464 resveratrol results in increased expression of CTSD CTD PMID:10402233 resveratrol decreases expression ISO RGD:1351014 6480464 resveratrol results in decreased expression of CTSD mRNA CTD PMID:14750165 resveratrol increases expression EXP   6480464 resveratrol results in increased expression of CTSD mRNA CTD PMID:16081268 resveratrol increases secretion ISO RGD:1351014 6480464 resveratrol results in increased secretion of CTSD protein CTD PMID:16393696 resveratrol affects expression ISO RGD:1351014 6480464 resveratrol affects the expression of CTSD mRNA CTD PMID:16393696 resveratrol affects response to substance ISO RGD:1351014 6480464 CTSD protein affects the susceptibility to resveratrol CTD PMID:17116725 resveratrol multiple interactions ISO RGD:1351014 6480464 ESR1 protein affects the reaction [resveratrol affects the secretion of CTSD protein]; more ... CTD PMID:16393696 resveratrol multiple interactions ISO RGD:1351014 6480464 CTSD protein affects the reaction [resveratrol affects the localization of CYCS protein]; more ... CTD PMID:17116725 retinyl acetate increases expression EXP   6480464 retinol acetate results in increased expression of CTSD mRNA CTD PMID:16772331 stilben-4-ol increases expression ISO RGD:1351014 6480464 4-hydroxystilbene results in increased expression of CTSD mRNA CTD PMID:19496085 stilbene-4,4'-diol increases expression ISO RGD:1351014 6480464 4,4'-dihydroxystilbene results in increased expression of CTSD mRNA CTD PMID:19496085 tamibarotene increases expression ISO RGD:1351014 6480464 Am 80 results in increased expression of CTSD mRNA; more ... CTD PMID:15498508 trans-resveratrol increases expression ISO RGD:1351014 6480464 resveratrol metabolite results in increased expression of CTSD mRNA CTD PMID:19496085 trans-resveratrol increases expression ISO RGD:1351014 6480464 resveratrol results in increased expression of CTSD mRNA CTD PMID:20878097 trans-resveratrol increases expression ISO RGD:1351014 6480464 resveratrol results in increased expression of CTSD protein CTD PMID:18089832 trans-resveratrol increases expression ISO RGD:1351014 6480464 resveratrol results in increased expression of CTSD CTD PMID:10402233 trans-resveratrol decreases expression ISO RGD:1351014 6480464 resveratrol results in decreased expression of CTSD mRNA CTD PMID:14750165 trans-resveratrol multiple interactions ISO RGD:1351014 6480464 CTSD protein affects the reaction [resveratrol affects the localization of CYCS protein]; more ... CTD PMID:17116725 trans-resveratrol multiple interactions ISO RGD:1351014 6480464 ESR1 protein affects the reaction [resveratrol affects the secretion of CTSD protein]; more ... CTD PMID:16393696 trans-resveratrol affects response to substance ISO RGD:1351014 6480464 CTSD protein affects the susceptibility to resveratrol CTD PMID:17116725 trans-resveratrol affects expression ISO RGD:1351014 6480464 resveratrol affects the expression of CTSD mRNA CTD PMID:16393696 trans-resveratrol increases secretion ISO RGD:1351014 6480464 resveratrol results in increased secretion of CTSD protein CTD PMID:16393696 trans-resveratrol increases expression EXP   6480464 resveratrol results in increased expression of CTSD mRNA CTD PMID:16081268 vancomycin decreases expression EXP   6480464 Vancomycin results in decreased expression of CTSD mRNA CTD PMID:18930951 Gene Ontology Annotations Biological Process Term Qualifier Evidence With Reference Notes Source Original Reference(s) autophagic vacuole assembly   IMP   2290270 MGI:MGI:3057045|PMID:15452145 MGI MGI:MGI:3057045 PMID:15452145 epithelial tube branching involved in lung morphogenesis NOT IMP   2290270 MGI:MGI:3722010|PMID:17500053 UniProtKB MGI:MGI:3722010 PMID:17500053 metabolic process   IDA   2290270 MGI:MGI:3848759|PMID:19293336 GOC MGI:MGI:3848759 PMID:19293336 metabolic process   IDA   2290270 MGI:MGI:3527911|PMID:15588329 GOC MGI:MGI:3527911 PMID:15588329 metabolic process   IDA   2290270 MGI:MGI:3653585|PMID:16423528 GOC MGI:MGI:3653585 PMID:16423528 proteolysis   IC GO:0008233 2290270 MGI:MGI:3527911|PMID:15588329 MGI MGI:MGI:3527911 PMID:15588329 proteolysis   ISO UniProtKB:P24268 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 Cellular Component Term Qualifier Evidence With Reference Notes Source Original Reference(s) extracellular region   IEA UniProtKB-KW:KW-0964 2290270 MGI:MGI:1354194 UniProtKB MGI:MGI:1354194 extracellular space   ISO UniProtKB:P07339 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 lysosome   IDA   2290270 MGI:MGI:2673081|PMID:12775715 MGI MGI:MGI:2673081 PMID:12775715 lysosome   ISO UniProtKB:P18242 2290270 MGI:MGI:3794910|PMID:18337546 MGI MGI:MGI:3794910 PMID:18337546 lysosome   ISO UniProtKB:P24268 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 lysosome   ISO UniProtKB:P07339 2290270 MGI:MGI:2154458 MGI MGI:MGI:2154458 lysosome   IDA   2290270 MGI:MGI:3057045|PMID:15452145 MGI MGI:MGI:3057045 PMID:15452145 lysosome   IDA   2290270 MGI:MGI:86330|PMID:9034150 MGI MGI:MGI:86330 PMID:9034150 lysosome   IDA   2290270 MGI:MGI:3608104|PMID:16242638 MGI MGI:MGI:3608104 PMID:16242638 lysosome   IDA   2290270 MGI:MGI:1352198|PMID:10591619 MGI MGI:MGI:1352198 PMID:10591619 lysosome   IDA   2290270 MGI:MGI:1271008|PMID:9645704 MGI MGI:MGI:1271008 PMID:9645704 mitochondrion   IDA   2290270 MGI:MGI:2682130|PMID:14651853 MGI MGI:MGI:2682130 PMID:14651853 Molecular Function Term Qualifier Evidence With Reference Notes Source Original Reference(s) aspartic-type endopeptidase activity   IDA   2290270 MGI:MGI:3848759|PMID:19293336 MGI MGI:MGI:3848759 PMID:19293336 endopeptidase activity   ISO UniProtKB:P24268 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 hydrolase activity   IEA UniProtKB-KW:KW-0378 2290270 MGI:MGI:1354194 UniProtKB MGI:MGI:1354194 peptidase activity   IDA   2290270 MGI:MGI:3653585|PMID:16423528 MGI MGI:MGI:3653585 PMID:16423528 peptidase activity   IDA   2290270 MGI:MGI:3527911|PMID:15588329 MGI MGI:MGI:3527911 PMID:15588329 peptide binding   ISO UniProtKB:P24268 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 Molecular Pathway Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) autophagy pathway   ISS RGD:621511 1643198   RGD   ceramide signaling pathway   ISO RGD:1351014 6484113   PID PID:200119 Mycobacterium tuberculosis infection pathway   IEA RGD:732637 6907045   KEGG mmu:05152 External Database Links KEGG Pathway Lysosome Tuberculosis Pathway Interaction Database Ceramide signaling pathway (PID:200119) Direct p53 effectors (PID:200120) LKB1 signaling events (PID:200074) Validated nuclear estrogen receptor alpha network (PID:200158) Phenotype Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) abnormal antigen presentation   IAGP   5509061   MGI PMID:9539769 abnormal apoptosis   IAGP   5509061   MGI PMID:11567042 abnormal crypts of Lieberkuhn morphology   IAGP   5509061   MGI PMID:7641679 abnormal ileum morphology   IAGP   5509061   MGI PMID:7641679 abnormal intestinal mucosa morphology   IAGP   5509061   MGI PMID:11567042 abnormal intestinal mucosa morphology   IAGP   5509061   MGI PMID:7641679 abnormal microglial cell morphology   IAGP   5509061   MGI PMID:11567042 abnormal retina morphology   IAGP   5509061   MGI PMID:12676526 abnormal spleen B cell follicle morphology   IAGP   5509061   MGI PMID:7641679 abnormal spleen white pulp morphology   IAGP   5509061   MGI PMID:7641679 ataxia   IAGP   5509061   MGI PMID:7641679 blindness   IAGP   5509061   MGI PMID:12676526 bradykinesia   IAGP   5509061   MGI PMID:7641679 decreased body weight   IAGP   5509061   MGI PMID:11567042 decreased body weight   IAGP   5509061   MGI PMID:7641679 decreased double-positive T cell number   IAGP   5509061   MGI PMID:7641679 decreased lymphocyte cell number   IAGP   5509061   MGI PMID:7641679 lysosomal protein accumulation   IAGP   5509061   MGI PMID:10995834 premature death   IAGP   5509061   MGI PMID:11567042 premature death   IAGP   5509061   MGI PMID:7641679 retinal photoreceptor degeneration   IAGP   5509061   MGI PMID:12676526 seizures   IAGP   5509061   MGI PMID:10995834 seizures   IAGP   5509061   MGI PMID:11567042 thrombosis   IAGP   5509061   MGI PMID:7641679 thymus hypoplasia   IAGP   5509061   MGI PMID:7641679 tonic seizures   IAGP   5509061   MGI PMID:10995834 Disease Annotations Alzheimer Disease  (ISS) Atherosclerosis  (IGI) Ceroid Lipofuscinosis, Neuronal, 10  (ISS) Gene-Chemical Interaction Annotations (+)-alpha-tocopherol  (ISO) (+)-pilocarpine  (ISO) (-)-epigallocatechin 3-gallate  (ISO) (R)-lipoic acid  (ISO) (S)-amphetamine  (EXP) 1,2,4-trimethylbenzene  (ISO) 17beta-estradiol  (ISO) 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO) 2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO) 2-amino-2-deoxy-D-glucopyranose  (ISO) 2-butoxyethanol  (EXP) 2-nitrofluorene  (ISO) 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO) 3,4-methylenedioxymethamphetamine  (EXP) 3-methylcholanthrene  (ISO) 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO) 6alpha-methylprednisolone  (ISO) 7,12-dimethyltetraphene  (ISO) aflatoxin B1  (ISO) aldehydo-D-glucosamine  (ISO) all-trans-retinoic acid  (ISO) amlodipine  (ISO) ammonium chloride  (ISO) benzo[a]pyrene  (EXP,ISO) beta-D-glucosamine  (ISO) bisphenol A  (ISO) cadmium dichloride  (ISO) chloroquine  (ISO) choline  (EXP) cimetidine  (ISO) cis-caffeic acid  (ISO) cisplatin  (EXP) clofibrate  (EXP) cobalt dichloride  (ISO) cocaine  (EXP) copper atom  (ISO) copper(0)  (ISO) curcumin  (ISO) cyclophosphamide  (EXP) cyclosporin A  (ISO) cysteamine  (ISO) DDT  (ISO) Delta(9)-tetrahydrocannabinol  (ISO) dexamethasone  (EXP) diazoxide  (ISO) dibutyl phthalate  (ISO) diethylstilbestrol  (ISO) disodium cromoglycate  (EXP) diuron  (ISO) doxorubicin  (ISO) ellagic acid  (ISO) emodin  (ISO) ethambutol  (ISO) ferulic acid  (ISO) folic acid  (EXP) fulvestrant  (ISO) fumonisin B1  (EXP) genistein  (EXP,ISO) hydrogen peroxide  (ISO) indole-3-methanol  (ISO) isoprenaline  (ISO) L-ascorbic acid  (ISO) L-methionine  (EXP) linalool  (ISO) lipoic acid  (ISO) lithium atom  (ISO) lucanthone  (ISO) malathion  (EXP) mangiferin  (ISO) melatonin  (ISO) methamphetamine  (ISO) methapyrilene  (ISO) N-nitrosodimethylamine  (ISO) N-tosyl-L-phenylalanyl chloromethyl ketone  (ISO) naringin  (ISO) nitric oxide  (ISO) nitroglycerin  (ISO) omeprazole  (ISO) paracetamol  (EXP) paraquat  (EXP) phenacetin  (ISO) phenobarbital  (ISO) phenylhydrazine  (ISO) piperonyl butoxide  (ISO) pirimiphos-methyl  (ISO) pirinixic acid  (EXP,ISO) pregnenolone 16alpha-carbonitrile  (ISO) pristane  (EXP) propiconazole  (EXP) quercetin  (ISO) resveratrol  (EXP,ISO) retinyl acetate  (EXP) stilben-4-ol  (ISO) stilbene-4,4'-diol  (ISO) tamibarotene  (ISO) trans-resveratrol  (EXP,ISO) vancomycin  (EXP) Gene Ontology Annotations Biological Process autophagic vacuole assembly  (IMP) epithelial tube branching involved in lung morphogenesis  (IMP) metabolic process  (IDA) proteolysis  (IC,ISO) Cellular Component extracellular region  (IEA) extracellular space  (ISO) lysosome  (IDA,ISO) mitochondrion  (IDA) Molecular Function aspartic-type endopeptidase activity  (IDA) endopeptidase activity  (ISO) hydrolase activity  (IEA) peptidase activity  (IDA) peptide binding  (ISO) Molecular Pathway Annotations autophagy pathway  (ISS) ceramide signaling pathway  (ISO) Mycobacterium tuberculosis infection pathway  (IEA) External Database Links KEGG Pathway Lysosome Tuberculosis Pathway Interaction Database Ceramide signaling pathway (PID:200119) Direct p53 effectors (PID:200120) LKB1 signaling events (PID:200074) Validated nuclear estrogen receptor alpha network (PID:200158) Phenotype Annotations abnormal antigen presentation  (IAGP) abnormal apoptosis  (IAGP) abnormal crypts of Lieberkuhn morphology  (IAGP) abnormal ileum morphology  (IAGP) abnormal intestinal mucosa morphology  (IAGP) abnormal microglial cell morphology  (IAGP) abnormal retina morphology  (IAGP) abnormal spleen B cell follicle morphology  (IAGP) abnormal spleen white pulp morphology  (IAGP) ataxia  (IAGP) blindness  (IAGP) bradykinesia  (IAGP) decreased body weight  (IAGP) decreased double-positive T cell number  (IAGP) decreased lymphocyte cell number  (IAGP) lysosomal protein accumulation  (IAGP) premature death  (IAGP) retinal photoreceptor degeneration  (IAGP) seizures  (IAGP) thrombosis  (IAGP) thymus hypoplasia  (IAGP) tonic seizures  (IAGP) References - curated 1. Jormsjo S, etal., Am J Pathol. 2002 Sep;161(3):939-45. 2. Menzer G, etal., Am J Med Genet 2001 Mar 8;105(2):179-82. 3. MGD data from the GO Consortium 4. MGD IEA 5. Mootha VK, etal., Cell 2003 Nov 26;115(5):629-40. 6. Pipeline to import KEGG annotations from KEGG into RGD Pathway Ontology 7. Pipeline to import Pathway Interaction Database annotations from NCI into RGD 8. RGD automated import pipeline 9. RGD automated import pipeline for gene-chemical interactions 10. RGD Automated Pipelines 11. Sukhova GK, etal., J Clin Invest. 1998 Aug 1;102(3):576-83. 12. Tyynela J, etal., EMBO J 2000 Jun 15;19(12):2786-92. 13. Wohlgemuth SE, etal., Rejuvenation Res. 2007 Sep;10(3):281-92. References - uncurated PubMed 10349636   10523518   10591619   10633857   10922068   10995834   11042159   11076861   11217851   11567042   11813165   11821259   12062453   12117300   12350228   12440525   12466851   12477932   12676526   12775715   12904583   1372572   14739942   15126630   15452145   15489334   15518240   15582152   15588329   15592854   15665831   15782199   15860733   15958652   15992379   16123398   16141072   16141073   16170054   16177003   16242638   16259009   16314482   16423528   16424157   16602821   16920965   16959874   16966329   16987511   17289576   17314303   17500053   17548631   17553802   17570679   18001291   18091563   18202773   18287559   18299403   18337546   18498441   18596167   18702517   19021916   19026003   19116891   19119233   19125694   19176312   19203374   19293336   19799774   19819948   19845830   20017393   20489146   20541250   20551175   20560835   20592493   21116106   21123180   21267068   21311773   21474794   21648018   21677750   21966382   22008266   22053177   22245096   22337873   22439866   2263503   22854957   22964611   23250759   23315080   2374732   7498407   7641679   7788526   8011168   9034150   9539769   9645704   9916995 RGD Disease Portals Ctsd has been annotated in the following RGD Disease Portals. Cancer Pathways Cardiovascular Diseases Cardiovascular Pathways Diabetes Diseases Diabetes Pathways Immune and Inflammatory Pathways Immune and Inflammatory Phenotypes Neurological Diseases Neurological Pathways Neurological Phenotypes Obesity Diseases Obesity Pathways Obesity Phenotypes Respiratory Pathways Genomics Comparative Map Data Ctsd   (Mus musculus) Map Chr Position Strand Source Mouse Genome Assembly GRCm38 7 142,375,916 - 142,387,870 - NCBI Mouse cM Map 7   - NCBI Mouse Celera Assembly 7 142,131,673 - 142,143,627 - NCBI Mouse Genome Assembly Build 37 7 149,561,821 - 149,573,775 - NCBI Mouse Genome Assembly Build 36.1 7 149,561,821 - 149,573,775 - NCBI Mouse Cytogenetic Map 7 F5   NCBI CTSD   (Homo sapiens) Map Chr Position Strand Source Human Alternate Assembly CHM1_1 11 1,708,731 - 1,719,969 - NCBI Human Genome Assembly HuRef 11 1,564,872 - 1,576,226 - NCBI Human Genome Assembly GRCh37 11 1,773,982 - 1,785,222 - NCBI Human Genome Assembly Build 36 11 1,730,561 - 1,741,798 - NCBI Human Cytogenetic Map 11 p15.5   NCBI Human Genome Assembly 11 1,730,560 - 1,741,798   NCBI Ctsd   (Rattus norvegicus) Map Chr Position Strand Source Rat Cytogenetic Map 1 q41   NCBI RGSC Genome Assembly v5.0 1 222,436,922 - 222,448,798 - NCBI RGSC Genome Assembly v3.4 1 202,619,669 - 202,631,545 - NCBI Rat Celera Assembly 1 195,146,345 - 195,158,236 - NCBI Genome Assembly 3.1 1 202,779,384 - 202,791,261 - NCBI Position Markers Ctsd   Map Chr Position Strand Source Mouse Genome Assembly GRCm38 7 142,376,196 - 142,377,426   UniSTS Mouse cM Map 7     UniSTS Mouse Celera Assembly 7 142,131,953 - 142,133,183   UniSTS Mouse Genome Assembly Build 37 7 149,562,101 - 149,563,331   UniSTS Mouse Cytogenetic Map 7 F5   UniSTS QTLs in Region (Mouse Genome Assembly Build 37) The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer RGD ID Symbol Name LOD P Value Trait Sub Trait Chr Start Stop Species 1301547 Bgeq6_m body growth early QTL 6 (mouse) Not determined 7 135030319 152509964 Mouse 1300566 Sluc8_m susceptibility to lung cancer 8 (mouse) Not determined 7 135030319 152509964 Mouse 1301590 Pbwg3_m postnatal body weight growth 3 (mouse) Not determined 7 134943409 152509964 Mouse 1301195 Mlviq1_m murine leukemia virus infection QTL (mouse) Not determined 7 134795777 152509964 Mouse 4142010 Myci1_m myocardial infarction 1 (mouse) Not determined 7 132551823 152509964 Mouse 1559008 Lith22_m lithogenic gene 22 (mouse) Not determined 7 126722527 152509964 Mouse 1357880 Brmth6_m behavioral response to methamphetamines 6 (mouse) Not determined 7 126722527 152509964 Mouse 1301773 Stheal7_m soft tissue heal 7 (mouse) Not determined 7 126722527 152509964 Mouse 1301903 Tlsm1_m thymic lymphoma susceptible 1 (mouse) Not determined 7 125760661 152509964 Mouse 1300677 Bmd9_m bone mineral density 9 (mouse) Not determined 7 124224043 152509964 Mouse 1301470 Vmbic3_m ventral midbrain iron content 3 (mouse) Not determined 7 122448713 152509964 Mouse 4142224 Cia42_m collagen induced arthritis 42 (mouse) Not determined 7 122448713 152509964 Mouse 1357462 Hlbsb1_m hepatic lipase activity in BSB 1 (mouse) Not determined 7 120807110 152509964 Mouse 1300747 Skts2_m skin tumor susceptibility 2 (mouse) Not determined 7 120464517 152509964 Mouse 1300635 Dice2_m determination of interleukin 4 commitment 2 (mouse) Not determined 7 119360966 152509964 Mouse 1302032 Alcp12_m alcohol preference locus 12 (mouse) Not determined 7 118707912 152509964 Mouse 1301898 Alcp14_m alcohol preference locus 14 (mouse) Not determined 7 118707912 152509964 Mouse 1300670 Sluc19_m susceptibility to lung cancer 19 (mouse) Not determined 7 118707912 152509964 Mouse 1558880 Scc12_m colon tumor susceptibility 12 (mouse) Not determined 7 118509025 152509126 Mouse 1357663 Rthyd1_m resistance to thymic deletion 1 (mouse) Not determined 7 115776553 149776641 Mouse Sequence Nucleotide Sequences Nucleotide RefSeqs NM_009983 (Get FASTA) Search GEO for Microarray Profiles GenBank Nucleotide AAHY01067316 (Get FASTA) Search GEO for Microarray Profiles   AC034099 (Get FASTA) Search GEO for Microarray Profiles   AK089294 (Get FASTA) Search GEO for Microarray Profiles   AK150363 (Get FASTA) Search GEO for Microarray Profiles   AK150364 (Get FASTA) Search GEO for Microarray Profiles   AK150579 (Get FASTA) Search GEO for Microarray Profiles   AK150622 (Get FASTA) Search GEO for Microarray Profiles   AK150636 (Get FASTA) Search GEO for Microarray Profiles   AK150694 (Get FASTA) Search GEO for Microarray Profiles   AK150768 (Get FASTA) Search GEO for Microarray Profiles   AK150946 (Get FASTA) Search GEO for Microarray Profiles   AK151256 (Get FASTA) Search GEO for Microarray Profiles   AK151275 (Get FASTA) Search GEO for Microarray Profiles   AK151276 (Get FASTA) Search GEO for Microarray Profiles   AK151374 (Get FASTA) Search GEO for Microarray Profiles   AK151829 (Get FASTA) Search GEO for Microarray Profiles   AK151962 (Get FASTA) Search GEO for Microarray Profiles   AK152036 (Get FASTA) Search GEO for Microarray Profiles   AK152045 (Get FASTA) Search GEO for Microarray Profiles   AK152168 (Get FASTA) Search GEO for Microarray Profiles   AK152187 (Get FASTA) Search GEO for Microarray Profiles   AK152188 (Get FASTA) Search GEO for Microarray Profiles   AK152406 (Get FASTA) Search GEO for Microarray Profiles   AK152458 (Get FASTA) Search GEO for Microarray Profiles   AK152567 (Get FASTA) Search GEO for Microarray Profiles   AK152578 (Get FASTA) Search GEO for Microarray Profiles   AK152593 (Get FASTA) Search GEO for Microarray Profiles   AK152638 (Get FASTA) Search GEO for Microarray Profiles   AK152680 (Get FASTA) Search GEO for Microarray Profiles   AK152828 (Get FASTA) Search GEO for Microarray Profiles   AK152881 (Get FASTA) Search GEO for Microarray Profiles   AK152892 (Get FASTA) Search GEO for Microarray Profiles   AK153191 (Get FASTA) Search GEO for Microarray Profiles   AK153291 (Get FASTA) Search GEO for Microarray Profiles   AK159097 (Get FASTA) Search GEO for Microarray Profiles   AK159209 (Get FASTA) Search GEO for Microarray Profiles   AK159440 (Get FASTA) Search GEO for Microarray Profiles   AK159490 (Get FASTA) Search GEO for Microarray Profiles   AK159512 (Get FASTA) Search GEO for Microarray Profiles   AK159580 (Get FASTA) Search GEO for Microarray Profiles   AK159642 (Get FASTA) Search GEO for Microarray Profiles   AK159743 (Get FASTA) Search GEO for Microarray Profiles   AK159896 (Get FASTA) Search GEO for Microarray Profiles   AK159970 (Get FASTA) Search GEO for Microarray Profiles   AK165227 (Get FASTA) Search GEO for Microarray Profiles   AK166864 (Get FASTA) Search GEO for Microarray Profiles   AK166938 (Get FASTA) Search GEO for Microarray Profiles   AK167143 (Get FASTA) Search GEO for Microarray Profiles   AK167366 (Get FASTA) Search GEO for Microarray Profiles   AK167698 (Get FASTA) Search GEO for Microarray Profiles   AK167750 (Get FASTA) Search GEO for Microarray Profiles   AK167867 (Get FASTA) Search GEO for Microarray Profiles   AK169139 (Get FASTA) Search GEO for Microarray Profiles   AK171195 (Get FASTA) Search GEO for Microarray Profiles   AK172583 (Get FASTA) Search GEO for Microarray Profiles   AK177774 (Get FASTA) Search GEO for Microarray Profiles   AK179798 (Get FASTA) Search GEO for Microarray Profiles   AK180828 (Get FASTA) Search GEO for Microarray Profiles   AK183526 (Get FASTA) Search GEO for Microarray Profiles   AK194256 (Get FASTA) Search GEO for Microarray Profiles   AK194597 (Get FASTA) Search GEO for Microarray Profiles   AK195021 (Get FASTA) Search GEO for Microarray Profiles   AK197320 (Get FASTA) Search GEO for Microarray Profiles   AK205399 (Get FASTA) Search GEO for Microarray Profiles   AK206206 (Get FASTA) Search GEO for Microarray Profiles   AK206787 (Get FASTA) Search GEO for Microarray Profiles   AK210409 (Get FASTA) Search GEO for Microarray Profiles   AK213259 (Get FASTA) Search GEO for Microarray Profiles   AK213518 (Get FASTA) Search GEO for Microarray Profiles   AK213803 (Get FASTA) Search GEO for Microarray Profiles   AK214634 (Get FASTA) Search GEO for Microarray Profiles   AK216050 (Get FASTA) Search GEO for Microarray Profiles   BC019682 (Get FASTA) Search GEO for Microarray Profiles   BC048900 (Get FASTA) Search GEO for Microarray Profiles   BC053937 (Get FASTA) Search GEO for Microarray Profiles   BC053940 (Get FASTA) Search GEO for Microarray Profiles   BC054758 (Get FASTA) Search GEO for Microarray Profiles   BC057931 (Get FASTA) Search GEO for Microarray Profiles   CH466531 (Get FASTA) Search GEO for Microarray Profiles   U23098 (Get FASTA) Search GEO for Microarray Profiles   X52886 (Get FASTA) Search GEO for Microarray Profiles   X53337 (Get FASTA) Search GEO for Microarray Profiles   X68378 (Get FASTA) Search GEO for Microarray Profiles   X68379 (Get FASTA) Search GEO for Microarray Profiles   X68380 (Get FASTA) Search GEO for Microarray Profiles   X68381 (Get FASTA) Search GEO for Microarray Profiles   X68382 (Get FASTA) Search GEO for Microarray Profiles   X68383 (Get FASTA) Search GEO for Microarray Profiles Reference Sequences RefSeq Acc Id: NM_009983 RefSeq Status: PROVISIONAL Type: CODING Protein Acc Id: NP_034113 Peptide Label: precursor Position: Map Chr Position Strand Source Mouse Genome Assembly GRCm38 7 142,375,916 - 142,387,870 - ENTREZGENE Mouse cM Map 7   - ENTREZGENE Mouse Celera Assembly 7 142,131,673 - 142,143,627 - RGD Mouse Genome Assembly Build 37 7 149,561,821 - 149,573,775 - RGD Protein Sequences Protein RefSeqs NP_034113 (Get FASTA) GenBank Protein AAH19682 (Get FASTA)   AAH48900 (Get FASTA)   AAH54758 (Get FASTA)   AAH57931 (Get FASTA)   BAC40831 (Get FASTA)   BAE29498 (Get FASTA)   BAE29499 (Get FASTA)   BAE29674 (Get FASTA)   BAE29712 (Get FASTA)   BAE29725 (Get FASTA)   BAE29773 (Get FASTA)   BAE29834 (Get FASTA)   BAE29980 (Get FASTA)   BAE30245 (Get FASTA)   BAE30262 (Get FASTA)   BAE30263 (Get FASTA)   BAE30346 (Get FASTA)   BAE30724 (Get FASTA)   BAE30833 (Get FASTA)   BAE30895 (Get FASTA)   BAE30902 (Get FASTA)   BAE31001 (Get FASTA)   BAE31018 (Get FASTA)   BAE31019 (Get FASTA)   BAE31193 (Get FASTA)   BAE31236 (Get FASTA)   BAE31319 (Get FASTA)   BAE31329 (Get FASTA)   BAE31342 (Get FASTA)   BAE31380 (Get FASTA)   BAE31412 (Get FASTA)   BAE31529 (Get FASTA)   BAE31566 (Get FASTA)   BAE31575 (Get FASTA)   BAE31791 (Get FASTA)   BAE31874 (Get FASTA)   BAE34813 (Get FASTA)   BAE34900 (Get FASTA)   BAE35086 (Get FASTA)   BAE35144 (Get FASTA)   BAE35200 (Get FASTA)   BAE35255 (Get FASTA)   BAE35336 (Get FASTA)   BAE35462 (Get FASTA)   BAE35523 (Get FASTA)   BAE39078 (Get FASTA)   BAE39131 (Get FASTA)   BAE39288 (Get FASTA)   BAE39462 (Get FASTA)   BAE39786 (Get FASTA)   BAE39883 (Get FASTA)   BAE40918 (Get FASTA)   BAE42305 (Get FASTA)   CAA37067 (Get FASTA)   CAA37423 (Get FASTA)   CAA48453 (Get FASTA)   EDL18142 (Get FASTA)   EDL18143 (Get FASTA)   EDL18144 (Get FASTA)   P18242 (Get FASTA) Promoters RGD ID: 6848113 Promoter ID: MM_ACW:46559 Type: Non-CpG SO ACC ID: SO:0000170 Source: MPROMDB Tissues & Cell Lines: BoneMarrow_0Hour,   BoneMarrow_4Hour,   Kidney,   Liver,   Lung Transcripts: CTSD.ESEP07 Position: Map Chr Position Strand Source Mouse Genome Assembly Build 36.1 7 149,563,016 - 149,563,617 - MPROMDB RGD ID: 6848114 Promoter ID: MM_ACW:46560 Type: Non-CpG SO ACC ID: SO:0000170 Source: MPROMDB Tissues & Cell Lines: Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6 Transcripts: CTSD.CSEP07 Position: Map Chr Position Strand Source Mouse Genome Assembly Build 36.1 7 149,566,679 - 149,567,179 - MPROMDB RGD ID: 6840891 Promoter ID: MM_KWN:53327 Type: Non-CpG SO ACC ID: SO:0000170 Source: MPROMDB Tissues & Cell Lines: BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   MEF_B6 Transcripts: OTTMUST00000084824 Position: Map Chr Position Strand Source Mouse Genome Assembly Build 36.1 7 149,568,286 - 149,569,487 - MPROMDB RGD ID: 6849246 Promoter ID: MM_XEF:6902 Type: Non-CpG SO ACC ID: SO:0000170 Source: MPROMDB Tissues & Cell Lines: 3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_4Hour,   Kidney,   Lung,   MEF_B4,   MEF_B6 Transcripts: NM_001078584,   NM_001132020,   NM_001142903,   NM_131710 Position: Map Chr Position Strand Source Mouse Genome Assembly Build 36.1 7 149,571,416 - 149,572,377 - MPROMDB RGD ID: 6840890 Promoter ID: MM_KWN:53328 Type: CpG-Island SO ACC ID: SO:0000170 Source: MPROMDB Tissues & Cell Lines: 3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen Transcripts: ENSMUST00000008035,   OTTMUST00000045257,   OTTMUST00000045258,   OTTMUST00000072696 Position: Map Chr Position Strand Source Mouse Genome Assembly Build 36.1 7 149,573,586 - 149,574,237 - MPROMDB RGD ID: 6881818 Promoter ID: EPDNEW_M4360 Type: preliminary Name: Ctsd_1 Description: cathepsin D SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) Position: Map Chr Position Strand Source Mouse Genome Assembly Build 36.1 7 149,573,763 - 149,573,823   EPDNEW Additional Information External Database Links Database Acc Id Source(s) Ensembl Genes ENSMUSG00000007891 ENTREZGENE Ensembl Protein ENSMUSP00000121203 ENTREZGENE Ensembl Transcript ENSMUST00000151120 ENTREZGENE Entrez Gene 13033 ENTREZGENE Gene3D-CATH Pept_Aspartc_cat UniProtKB/Swiss-Prot Germonline ENSMUSG00000007891 HomoloGene Group ID 55616 ENTREZGENE InterPro Peptidase_A1 UniProtKB/Swiss-Prot   Peptidase_aspartic UniProtKB/Swiss-Prot   Peptidase_aspartic_AS UniProtKB/Swiss-Prot   Propep_A1 UniProtKB/Swiss-Prot IPI IPI00111013 UniProtKB/Swiss-Prot   IPI00404551 UniProtKB/TrEMBL   IPI00881091 UniProtKB/TrEMBL   IPI00927957 UniProtKB/TrEMBL   IPI00988110 UniProtKB/TrEMBL KEGG Report mmu:13033 ENTREZGENE, UniProtKB/Swiss-Prot MGD MGI:88562 ENTREZGENE PANTHER Peptidase_A1 UniProtKB/Swiss-Prot Pfam A1_Propeptide UniProtKB/Swiss-Prot   Asp UniProtKB/Swiss-Prot PRINTS PEPSIN UniProtKB/Swiss-Prot PROSITE ASP_PROTEASE UniProtKB/Swiss-Prot Superfamily-SCOP Pept_Aspartic UniProtKB/Swiss-Prot UniGene Mm.231395 ENTREZGENE UniProt CATD_MOUSE UniProtKB/Swiss-Prot   F6Y6L6_MOUSE UniProtKB/TrEMBL   F8WIR1_MOUSE UniProtKB/TrEMBL   Q05BF3_MOUSE UniProtKB/TrEMBL   Q3TIR0_MOUSE UniProtKB/TrEMBL   Q3TJN3_MOUSE UniProtKB/TrEMBL   Q3TWD0_MOUSE UniProtKB/TrEMBL   Q3TWL1_MOUSE UniProtKB/TrEMBL   Q3TWR6_MOUSE UniProtKB/TrEMBL   Q3TXL5_MOUSE UniProtKB/TrEMBL   Q3U651_MOUSE UniProtKB/TrEMBL   Q3U7I9_MOUSE UniProtKB/TrEMBL   Q3U7P0_MOUSE UniProtKB/TrEMBL   Q3U8W5_MOUSE UniProtKB/TrEMBL   Q3UAQ1_MOUSE UniProtKB/TrEMBL   Q3UC89_MOUSE UniProtKB/TrEMBL   Q3UCD9_MOUSE UniProtKB/TrEMBL   Q3UCW4_MOUSE UniProtKB/TrEMBL   Q8C243_MOUSE UniProtKB/TrEMBL   Q8VCK2_MOUSE UniProtKB/TrEMBL

More on Ctsd Entrez Gene Ensembl Gene Genome Browser MGI Report NCBI Map Viewer Vista Vista + UCSC RGD Object Information RGD ID: 732637 Created: 2004-01-12 Species: Mus musculus Last Modified: 2013-04-02 Status: ACTIVE