Rad51 (RAD51 recombinase) - Rat Genome Database

Name: Rad51
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Rad51 (RAD51 recombinase) Mus musculus

Analyze

Symbol:

Rad51

Name:

RAD51 recombinase

RGD ID:

1316728

MGI Page

MGI

Description:

Enables DNA strand exchange activity; chromatin binding activity; and single-stranded DNA binding activity. Involved in DNA metabolic process. Acts upstream of or within several processes, including DNA metabolic process; cellular response to hydroxyurea; and chromosome organization. Located in chromosome; cytoplasm; and male germ cell nucleus. Is active in site of double-strand break. Is expressed in several structures, including brain; compacted morula; gonad; hemolymphoid system; and paravertebral ganglion. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group R; breast cancer; congenital mirror movement disorder; and ovarian cancer. Orthologous to human RAD51 (RAD51 recombinase).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

AV304093; DNA repair protein RAD51 homolog 1; Rad; RAD51 homolog A; Rad51a; Re; Reca

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RAD51 (RAD51 recombinase)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Rad51 (RAD51 recombinase)	RGD	RGD
Chinchilla lanigera (long-tailed chinchilla):	Rad51 (RAD51 recombinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RAD51 (RAD51 recombinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RAD51 (RAD51 recombinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rad51 (RAD51 recombinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RAD51 (RAD51 recombinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RAD51 (RAD51 recombinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rad51 (RAD51 recombinase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	RAD51 (RAD51 recombinase)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Rattus norvegicus (Norway rat):	Rad51 (RAD51 recombinase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rad51 (RAD51 recombinase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RAD51	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rad-51	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	spn-A	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rad51	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	118,943,295 - 118,966,554 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	118,943,274 - 118,977,926 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	119,112,814 - 119,136,073 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	119,112,793 - 119,147,445 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	118,938,553 - 118,961,806 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	118,804,258 - 118,827,511 (+)	NCBI		MGSCv36	mm8
Celera	2	120,265,474 - 120,286,601 (+)	NCBI		Celera
Cytogenetic Map	2	E5	NCBI
cM Map	2	59.92	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bloom syndrome (ISO)

breast cancer (ISO)

Breast Cancer, Familial (ISO)

Breast Neoplasms (ISO)

cardiomyopathy (ISO)

colorectal cancer (ISO)

Experimental Liver Neoplasms (ISO)

Fanconi anemia complementation group R (ISO)

genetic disease (ISO)

Genetic Predisposition to Disease (ISO)

Head and Neck Neoplasms (ISO)

hereditary breast ovarian cancer syndrome (ISO)

Hereditary Neoplastic Syndromes (ISO)

hypertension (ISO)

Hypoxia (ISO)

Micronuclei, Chromosome-Defective (ISO)

Mirror Movements 2 (ISO)

ovarian cancer (ISO)

ovary epithelial cancer (ISO)

pancreatic cancer (ISO)

Triple Negative Breast Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-dexrazoxane (EXP)

(-)-demecolcine (ISO)

(-)-epigallocatechin 3-gallate (ISO)

1,1-dichloroethene (EXP)

1,2-dichloroethane (EXP)

1,4-dioxane (ISO)

1-naphthyl isothiocyanate (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (EXP)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,2',5,5'-tetrachlorobiphenyl (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-diaminotoluene (EXP)

3-methylcholanthrene (EXP)

4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid (ISO)

4-hydroperoxycyclophosphamide (ISO)

4-hydroxynon-2-enal (EXP)

4-hydroxyphenyl retinamide (EXP)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (ISO)

7,12-dimethyltetraphene (EXP,ISO)

7,9-dihydro-1H-purine-2,6,8(3H)-trione (EXP)

acetamide (ISO)

acetylleucyl-leucyl-norleucinal (ISO)

acrylamide (ISO)

actinomycin D (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amsacrine (ISO)

anthra[1,9-cd]pyrazol-6(2H)-one (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (EXP)

benzene (EXP,ISO)

benzo[a]pyrene (EXP,ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[b]fluoranthene (EXP)

benzo[e]pyrene (ISO)

biphenyl-4-amine (ISO)

bis(2-chloroethyl) sulfide (EXP,ISO)

bis(2-ethylhexyl) phthalate (EXP,ISO)

bisphenol A (ISO)

Bisphenol A diglycidyl ether (EXP)

bortezomib (ISO)

bromoacetate (ISO)

bromobenzene (ISO)

busulfan (EXP)

cadmium dichloride (ISO)

calcitriol (ISO)

camptothecin (ISO)

cannabidiol (ISO)

carbamazepine (ISO)

carbon nanotube (EXP)

carmustine (ISO)

chlorambucil (ISO)

chlordecone (EXP)

chlorothalonil (EXP)

choline (EXP)

chromium(6+) (ISO)

chrysene (EXP)

cisplatin (EXP,ISO)

copper atom (EXP,ISO)

copper(0) (EXP,ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

crocidolite asbestos (EXP,ISO)

CU-O LINKAGE (ISO)

curcumin (ISO)

CX-5461 (ISO)

cyclophosphamide (EXP,ISO)

cyclosporin A (ISO)

cylindrospermopsin (ISO)

cypermethrin (EXP)

cytarabine (ISO)

decabromodiphenyl ether (EXP)

dexamethasone (EXP)

dibenz[a,h]anthracene (EXP)

dibenzofuran (ISO)

dichloroacetic acid (EXP)

diclofenac (ISO)

diethylstilbestrol (EXP)

dioxygen (ISO)

disodium selenite (ISO)

doxorubicin (ISO)

endosulfan (ISO)

Enterolactone (ISO)

entinostat (ISO)

epoxiconazole (EXP)

erlotinib hydrochloride (ISO)

erythromycin estolate (ISO)

estragole (ISO)

etoposide (ISO)

fenthion (ISO)

flumequine (EXP)

folic acid (EXP)

fulvestrant (ISO)

furan (ISO)

gallic acid (ISO)

gefitinib (ISO)

genistein (ISO)

gentamycin (ISO)

geraniol (ISO)

ginsenoside Rg1 (ISO)

gold atom (ISO)

gold(0) (ISO)

hydrogen peroxide (ISO)

idarubicin (EXP)

irinotecan (ISO)

L-methionine (EXP)

leflunomide (ISO)

lidocaine (ISO)

lipopolysaccharide (EXP)

lucanthone (ISO)

mechlorethamine (EXP)

MeIQx (EXP)

menadione (ISO)

methapyrilene (ISO)

methyl methanesulfonate (ISO)

mitomycin C (ISO)

myristicin (ISO)

N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (ISO)

N,N-dimethylformamide (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

N-nitrosodiethylamine (EXP,ISO)

nickel atom (ISO)

nickel dichloride (ISO)

Nonidet P-40 (ISO)

ochratoxin A (ISO)

olaparib (ISO)

oxaliplatin (ISO)

ozone (EXP)

paracetamol (ISO)

PCB138 (EXP)

perfluorooctanoic acid (ISO)

phenethyl isothiocyanate (ISO)

phenobarbital (EXP)

phosphoramide mustard (ISO)

phytoestrogen (ISO)

pifithrin-? (ISO)

pirinixic acid (EXP)

potassium chromate (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

prodigiosin (ISO)

progesterone (EXP)

propiconazole (EXP)

quercetin (ISO)

quizartinib (ISO)

resveratrol (ISO)

romidepsin (ISO)

rotenone (ISO)

SB 203580 (ISO)

silicon dioxide (EXP)

sirolimus (ISO)

sodium arsenite (EXP,ISO)

sodium dichromate (EXP,ISO)

sunitinib (ISO)

tamoxifen (ISO)

terbufos (ISO)

testosterone (ISO)

tetrachloromethane (EXP)

tetraphene (EXP)

thioacetamide (ISO)

titanium dioxide (EXP,ISO)

topotecan (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

trimellitic anhydride (EXP)

troglitazone (ISO)

trovafloxacin (EXP)

urethane (ISO)

valproic acid (EXP,ISO)

vorinostat (ISO)

zearalenone (EXP)

zinc oxide (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to alkaloid (IMP)

cellular response to camptothecin (ISO)

cellular response to cisplatin (ISO)

cellular response to gamma radiation (ISO)

cellular response to hydroxyurea (IMP)

cellular response to ionizing radiation (ISO)

chromosome organization involved in meiotic cell cycle (IBA,IMP)

DNA damage response (ISO,TAS)

DNA metabolic process (IEA)

DNA recombinase assembly (IBA,ISO)

DNA recombination (IEA)

DNA repair (TAS)

DNA strand invasion (IBA)

DNA unwinding involved in DNA replication (ISO)

double-strand break repair involved in meiotic recombination (IDA)

double-strand break repair via homologous recombination (IDA,IMP,ISO)

interstrand cross-link repair (ISO)

meiosis I (ISO)

meiotic cell cycle (IDA)

mitotic recombination (IBA)

mitotic recombination-dependent replication fork processing (IEA)

positive regulation of DNA ligation (ISO)

reciprocal meiotic recombination (IBA,IDA,TAS)

regulation of DNA damage checkpoint (NAS)

regulation of double-strand break repair via homologous recombination (ISO)

regulation of protein phosphorylation (IMP)

replication fork processing (IMP,ISO)

replication-born double-strand break repair via sister chromatid exchange (IMP)

response to glucoside (ISO)

response to organic cyclic compound (ISO)

response to toxic substance (ISO)

response to X-ray (ISO)

response to xenobiotic stimulus (ISO)

telomere maintenance via recombination (IGI)

telomere maintenance via telomere lengthening (IGI)

telomere organization (IMP)

Cellular Component

chromatin (ISO)

chromosome (IDA)

chromosome, telomeric region (IDA,ISO)

condensed chromosome (IDA)

condensed nuclear chromosome (IBA,IDA)

cytoplasm (IDA,ISO)

cytoskeleton (IEA)

cytosol (ISO)

lateral element (IDA,ISO)

male germ cell nucleus (IDA)

mitochondrion (ISO)

nuclear chromosome (ISO)

nuclear ubiquitin ligase complex (ISO)

nucleolus (ISO)

nucleoplasm (TAS)

nucleus (IDA,ISO)

perinuclear region of cytoplasm (ISO)

PML body (ISO)

presynaptic intermediate filament cytoskeleton (ISO)

protein-containing complex (ISO)

site of double-strand break (IDA,ISO)

synaptonemal complex (TAS)

Molecular Function

ATP binding (ISO)

ATP hydrolysis activity (IEA)

ATP-dependent activity, acting on DNA (IBA)

ATP-dependent DNA damage sensor activity (IEA)

chromatin binding (IDA,ISO)

DNA binding (IEA)

DNA polymerase binding (ISO)

DNA strand exchange activity (IBA,IDA,ISO)

double-stranded DNA binding (IBA,ISO)

enzyme binding (ISO)

identical protein binding (ISO)

nucleotide binding (IEA)

protein binding (IPI)

single-stranded DNA binding (IBA,IDA,ISO)

single-stranded DNA helicase activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

ceramide signaling pathway (IEA)

homologous recombination pathway of double-strand break repair (IEA,ISO)

pancreatic cancer pathway (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal double-strand DNA break repair (IAGP)

abnormal embryonic tissue morphology (IAGP)

abnormal male meiosis (IAGP)

abnormal seminiferous tubule morphology (IAGP)

abnormal spermatocyte morphology (IAGP)

abnormal spermatogenesis (IAGP)

abnormal spermatogonia morphology (IAGP)

absent amniotic cavity (IAGP)

absent inner cell mass proliferation (IAGP)

absent mesoderm (IAGP)

decreased cell proliferation (IAGP)

decreased embryo size (IAGP)

decreased male germ cell number (IAGP)

decreased testis weight (IAGP)

embryonic growth arrest (IAGP)

embryonic lethality before implantation, complete penetrance (IAGP)

embryonic lethality between implantation and somite formation, complete penetrance (IAGP)

embryonic lethality between somite formation and embryo turning, complete penetrance (IAGP)

increased cellular sensitivity to gamma-irradiation (IAGP)

increased embryonic epiblast cell apoptosis (IAGP)

increased male germ cell apoptosis (IAGP)

increased Sertoli cell number (IAGP)

male infertility (IAGP)

small testis (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies.	Antoniou AC, etal., Am J Hum Genet. 2007 Dec;81(6):1186-200. Epub 2007 Oct 16.
2.	Polymorphisms in DNA repair genes and epithelial ovarian cancer risk.	Auranen A, etal., Int J Cancer. 2005 Nov 20;117(4):611-8.
3.	Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.	Brady KP, etal., Genome Res 1997 Nov;7(11):1085-93.
4.	A specific RAD51 haplotype increases breast cancer risk in Jewish non-Ashkenazi high-risk women.	Gal I, etal., Eur J Cancer. 2006 May;42(8):1129-34. Epub 2006 Apr 18.
5.	Regulation of homologous recombination in eukaryotes.	Heyer WD, etal., Annu Rev Genet. 2010;44:113-39. doi: 10.1146/annurev-genet-051710-150955.
6.	The RAD51 135 G>C polymorphism modifies breast cancer and ovarian cancer risk in Polish BRCA1 mutation carriers.	Jakubowska A, etal., Cancer Epidemiol Biomarkers Prev. 2007 Feb;16(2):270-5.
7.	Functional annotation of a full-length mouse cDNA collection.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
8.	BRCA1 shields vascular smooth muscle cells from oxidative stress.	Lovren F, etal., J Thorac Cardiovasc Surg. 2014 Jun;147(6):1946-55, 1955.e1. doi: 10.1016/j.jtcvs.2013.09.060. Epub 2013 Nov 13.
9.	In vivo profiling of hypoxic gene expression in gliomas using the hypoxia marker EF5 and laser-capture microdissection.	Marotta D, etal., Cancer Res. 2011 Feb 1;71(3):779-89. doi: 10.1158/0008-5472.CAN-10-3061. Epub 2011 Jan 25.
10.	RAD51 up-regulation bypasses BRCA1 function and is a common feature of BRCA1-deficient breast tumors.	Martin RW, etal., Cancer Res. 2007 Oct 15;67(20):9658-65.
11.	MGDs mouse GO annotations	MGD data from the GO Consortium
12.	MGD IEA	MGD IEA
13.	Genetic instability in the RAD51 and BRCA1 regions in breast cancer.	Nowacka-Zawisza M, etal., Cell Mol Biol Lett. 2007;12(2):192-205. Epub 2006 Dec 18.
14.	Dinucleotide repeat polymorphisms of RAD51, BRCA1, BRCA2 gene regions in breast cancer.	Nowacka-Zawisza M, etal., Pathol Int. 2008 May;58(5):275-81.
15.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
16.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
17.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
18.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
20.	Disparate impact of butyroyloxymethyl diethylphosphate (AN-7), a histone deacetylase inhibitor, and doxorubicin in mice bearing a mammary tumor.	Tarasenko N, etal., PLoS One. 2012;7(2):e31393. doi: 10.1371/journal.pone.0031393. Epub 2012 Feb 23.
21.	Epigenetic reprogramming of liver cells in tamoxifen-induced rat hepatocarcinogenesis.	Tryndyak VP, etal., Mol Carcinog. 2007 Mar;46(3):187-97.
22.	[Expression of RAD51 and MAX in pancreatic cancer rats].	Yang L, etal., Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2010 Feb;35(2):146-51. doi: 10.3969/j.issn.1672-7347.2010.02.010.

Additional References at PubMed

PMID:7633422	PMID:7774567	PMID:8188269	PMID:8341671	PMID:8358431	PMID:8602360	PMID:8617512	PMID:8628240	PMID:8692798	PMID:8816780	PMID:8943369	PMID:9126738
PMID:9171369	PMID:9192668	PMID:9311981	PMID:9417871	PMID:9512535	PMID:9655934	PMID:9670959	PMID:9774970	PMID:10209103	PMID:10349636	PMID:10422536	PMID:10809667
PMID:10922068	PMID:11042159	PMID:11076861	PMID:11477095	PMID:11591653	PMID:11923292	PMID:12091911	PMID:12379650	PMID:12477932	PMID:12485996	PMID:12520002	PMID:12531026
PMID:12591952	PMID:12687013	PMID:12749858	PMID:12893777	PMID:12913077	PMID:14559999	PMID:14576820	PMID:14610273	PMID:14636569	PMID:14668445	PMID:14736746	PMID:14764457
PMID:15359272	PMID:15364958	PMID:15475264	PMID:15485900	PMID:15489334	PMID:15750625	PMID:15782199	PMID:15834424	PMID:15897881	PMID:15965906	PMID:16141072	PMID:16141073
PMID:16420439	PMID:16428451	PMID:17291760	PMID:17599069	PMID:17767921	PMID:17967808	PMID:18003859	PMID:18283110	PMID:18632630	PMID:18694567	PMID:18799693	PMID:18974875
PMID:18992372	PMID:19112184	PMID:19117011	PMID:19213844	PMID:19735653	PMID:19948482	PMID:20059948	PMID:20169201	PMID:20189471	PMID:20211142	PMID:20484223	PMID:20551173
PMID:20647542	PMID:20976249	PMID:20979543	PMID:21076401	PMID:21267068	PMID:21276791	PMID:21459848	PMID:21478856	PMID:21637789	PMID:21653319	PMID:21655083	PMID:21677750
PMID:21743440	PMID:21873635	PMID:21998700	PMID:22156371	PMID:22164254	PMID:22305526	PMID:22388890	PMID:22492707	PMID:22530760	PMID:22560297	PMID:22665067	PMID:22705496
PMID:22778135	PMID:22922362	PMID:23133398	PMID:23151479	PMID:23341130	PMID:23451117	PMID:23555294	PMID:23969417	PMID:24005329	PMID:24068956	PMID:24108124	PMID:24210700
PMID:24550317	PMID:24553289	PMID:24583581	PMID:24797475	PMID:24882376	PMID:24886500	PMID:24891606	PMID:24913804	PMID:24943459	PMID:24991985	PMID:25010009	PMID:25463395
PMID:25488918	PMID:25810472	PMID:26490168	PMID:26742488	PMID:26876348	PMID:27131790	PMID:27225532	PMID:27251002	PMID:27425845	PMID:27739607	PMID:27760146	PMID:27760317
PMID:28057929	PMID:28199840	PMID:28552778	PMID:28912125	PMID:29125140	PMID:29329290	PMID:29445148	PMID:29447390	PMID:29955025	PMID:30024881	PMID:30188106	PMID:30272023
PMID:30297419	PMID:30302025	PMID:30668564	PMID:30746471	PMID:30760716	PMID:30783098	PMID:30949703	PMID:31242413	PMID:31358751	PMID:31453335	PMID:31624230	PMID:32029273
PMID:32094118	PMID:32219340	PMID:32345962	PMID:32463460	PMID:32502153	PMID:32588736	PMID:32610038	PMID:32845237	PMID:32968282	PMID:33110058	PMID:33200984	PMID:33602822
PMID:33798452	PMID:33864208	PMID:34026442	PMID:34043941	PMID:34059773	PMID:34321999	PMID:34746147	PMID:34819065	PMID:34880491	PMID:35176943	PMID:35292640	PMID:35310947
PMID:35489071	PMID:35546066	PMID:35671285	PMID:35920200	PMID:35969748	PMID:36058112	PMID:36642183	PMID:36718792	PMID:36938872	PMID:37370140	PMID:37439366	PMID:37563658
PMID:37661798	PMID:37891173	PMID:37973188	PMID:38459011	PMID:38485951

Genomics

Comparative Map Data

Rad51
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	118,943,295 - 118,966,554 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	118,943,274 - 118,977,926 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	119,112,814 - 119,136,073 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	119,112,793 - 119,147,445 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	118,938,553 - 118,961,806 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	118,804,258 - 118,827,511 (+)	NCBI		MGSCv36	mm8
Celera	2	120,265,474 - 120,286,601 (+)	NCBI		Celera
Cytogenetic Map	2	E5	NCBI
cM Map	2	59.92	NCBI

RAD51
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	40,694,733 - 40,732,340 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	40,694,774 - 40,732,340 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	40,987,372 - 41,024,538 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	38,774,651 - 38,811,648 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	38,774,660 - 38,811,646	NCBI
Celera	15	17,755,220 - 17,792,245 (+)	NCBI		Celera
Cytogenetic Map	15	q15.1	NCBI
HuRef	15	17,834,870 - 17,872,189 (+)	NCBI		HuRef
CHM1_1	15	41,107,382 - 41,144,356 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	38,500,415 - 38,538,035 (+)	NCBI		T2T-CHM13v2.0

Rad51
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	126,554,210 - 126,578,888 (+)	NCBI		GRCr8
mRatBN7.2	3	106,099,753 - 106,125,038 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	106,100,381 - 106,125,035 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	109,773,488 - 109,798,183 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	118,369,034 - 118,393,719 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	116,029,412 - 116,054,104 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	110,918,240 - 110,942,920 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	110,918,243 - 110,942,917 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	117,468,402 - 117,493,566 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	105,625,265 - 105,650,392 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	3	105,013,953 - 105,038,371 (+)	NCBI		Celera
Cytogenetic Map	3	q35	NCBI

Rad51
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955416	7,566,686 - 7,590,628 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955416	7,566,715 - 7,590,628 (+)	NCBI	ChiLan1.0	ChiLan1.0

RAD51
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	29,938,330 - 29,973,033 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	34,089,788 - 34,123,970 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	19,638,310 - 19,672,474 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	37,891,061 - 37,925,207 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	37,891,056 - 37,925,207 (+)	Ensembl	panpan1.1		panPan2

RAD51
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	7,842,540 - 7,877,128 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	7,842,540 - 7,877,606 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	7,896,289 - 7,931,113 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	7,968,785 - 8,004,039 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	7,968,784 - 8,004,029 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	7,892,599 - 7,927,542 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	7,999,640 - 8,034,564 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	8,128,251 - 8,163,404 (+)	NCBI		UU_Cfam_GSD_1.0

Rad51
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	86,263,812 - 86,288,764 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	4,114,530 - 4,136,248 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	4,119,020 - 4,136,811 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RAD51
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	130,586,665 - 130,640,136 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	130,592,414 - 130,640,326 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	145,751,297 - 145,798,501 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RAD51
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	42,281,085 - 42,319,394 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	42,279,608 - 42,318,169 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	98,661,431 - 98,701,069 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rad51
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624804	7,957,253 - 7,983,619 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624804	7,957,175 - 7,983,078 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Rad51
779 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	2184
Count of miRNA genes:	748
Interacting mature miRNAs:	932
Transcripts:	ENSMUST00000028795, ENSMUST00000110828, ENSMUST00000140939, ENSMUST00000141389, ENSMUST00000143934, ENSMUST00000151406, ENSMUST00000152327, ENSMUST00000154683
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300793	Pcfm2_m	periosteal circumference and femur length 2 (mouse)			Not determined		2	111173704	145173821	Mouse
1300798	Actre3_m	activity response to ethanol 3 (mouse)			Not determined		2	112024987	128173821	Mouse
1300852	Lmr14_m	leishmaniasis resistance 14 (mouse)			Not determined		2	86095716	120095823	Mouse
1301029	T2dm3_m	type 2 diabetes mellitus 3 (mouse)			Not determined		2	114288075	132714157	Mouse
1301330	Tbbmd2_m	total body bone mineral density 2 (mouse)			Not determined		2	100942930	134943090	Mouse
1301344	Lith1_m	lithogenic gene 1 (mouse)			Not determined		2	45347635	145312647	Mouse
1301201	Chab1_m	cholesterol absorption 1 (mouse)			Not determined		2	111551028	145551163	Mouse
1301087	Bbaa15_m	B.burgdorferi-associated arthritis 15 (mouse)			Not determined		2	110489658	144489807	Mouse
1301098	Cd8mts3_m	CD8 memory T cell subset 3 (mouse)			Not determined		2	91089974	125090104	Mouse
1301295	Prdt1_m	prion disease incubation time 1 (mouse)			Not determined		2	116077623	150077741	Mouse
1301755	Hrq1_m	heart rate quantitative locus 1 (mouse)			Not determined		2	111173704	145173821	Mouse
1301825	Pbrgcsf1_m	peripheral blood stem cell response to granulocyte colony stimulating factor 1 (mouse)			Not determined		2	106233580	140233729	Mouse
1301834	Bits1_m	bitterness sensitivity 1 (mouse)			Not determined		2	87440643	121440778	Mouse
1301415	Actre4_m	activity response to ethanol 4 (mouse)			Not determined		2	112024987	128173821	Mouse
1301618	Bglu1_m	blood glucose level 1 (mouse)			Not determined		2	117942930	174324863	Mouse
1302174	Dssc2_m	dextran sodium sulfate induced colitis QTL2 (mouse)			Not determined		2	24224632	148700377	Mouse
1302033	Nsv1_m	Neuroadapted Sindbis viral RNA level 1 (mouse)			Not determined		2	111623386	145623526	Mouse
1302071	Fembrs1_m	femur breaking strength 1 (mouse)			Not determined		2	100942930	134943090	Mouse
1302203	Gvhd3_m	graft-versus host disease 3 (mouse)			Not determined		2	100942930	134943090	Mouse
1301905	Lgth2_m	body length 2 (mouse)			Not determined		2	111173704	145173821	Mouse
1301909	Smdq2_m	segregation of mitochondrial DNA QTL 2 (mouse)			Not determined		2	92778465	126778607	Mouse
1558881	Ses7_m	salmonella enteritidis susceptibility 7 (mouse)			Not determined		2	116306330	150306474	Mouse
1357577	Trmq3_m	T cell ratio modifier QTL 3 (mouse)			Not determined		2	60520612	119355518	Mouse
1558825	Aabpr_m	aberrant activation of B cell proliferation (mouse)			Not determined		2	116033229	122207534	Mouse
1558990	Skmw9_m	skeletal muscle weight 9 (mouse)			Not determined		2	111173704	145173821	Mouse
4141155	Plast2b_m	plasma plant sterol 2b (mouse)			Not determined		2	84013198	148522175	Mouse
4141802	Ignpq1_m	IgA nephropathy QTL 1 (mouse)			Not determined		2	100824060	134824269	Mouse
4141854	T2dm2sa_m	type 2 diabetes mellitus 2 in SMXA RI mice (mouse)			Not determined		2	29307947	148374934	Mouse
4142223	Femwf4_m	femur work to failure 4 (mouse)			Not determined			88143423	122143570	Mouse
5491196	Mobq6_m	multigenic obesity QTL 6 (mouse)			Not determined		2	85724269	180896594	Mouse
5491197	Mobq5_m	multigenic obesity QTL 5 (mouse)			Not determined		2	65269746	162518926	Mouse
11038696	Ltpr2f_m	Leishmania tropica response 2f (mouse)					2	115212857	149212994	Mouse
11038697	Ltpr2d_m	Leishmania tropica response 2d (mouse)					2	86095716	120095823	Mouse
11038698	Ltpr2c_m	Leishmania tropica response 2c (mouse)					2	86095716	120095823	Mouse
11038699	Ltpr2b_m	Leishmania tropica response 2b (mouse)					2	112212746	146213005	Mouse
11038700	Ltpr2a_m	Leishmania tropica response 2a (mouse)					2	112212746	146213005	Mouse
11038702	Ltpr2_m	Leishmania tropica response 2 (mouse)					2	103095716	167212356	Mouse
11041906	Lmr28a_m	leishmaniasis resistance 28a (mouse)					2	103095716	129213005	Mouse
11528549	Sluc31_m	susceptibility to lung cancer 31 (mouse)					2	74524117	129213005	Mouse
10043875	Bw25_m	body weight QTL 25 (mouse)			Not determined		2	107255676	141255676	Mouse
11039520	Ltpr2h_m	Leishmania tropica response 2h (mouse)					2	112212746	146213005	Mouse
11039521	Ltpr2g_m	Leishmania tropica response 2g (mouse)					2	115212857	149212994	Mouse
10412082	Hylaq1_m	Hyperlocomotor activity related QTL 1 (mouse)			Not determined		2	84013198	148667470	Mouse
10045885	Cplaq15_m	circadian period of locomotor activity 15 (mouse)			Not determined		2	110916118	154354667	Mouse
11049565	Lmr28g_m	leishmaniasis resistance 28g (mouse)					2	86095716	120095823	Mouse
11049568	Lmr28c_m	leishmaniasis resistance 28c (mouse)					2	97123370	131123532	Mouse
11049569	Lmr28d_m	leishmaniasis resistance 28d (mouse)					2	97123370	131123532	Mouse
12910795	Pwbwq5_m	post-weaning body weight QTL 5 (mouse)					2	118589253	160611165	Mouse
12910799	Pwgrq2_m	pre-weaning growth rate QTL 2 (mouse)					2	118589253	160611165	Mouse
12910812	Pwgrq1_m	pre-weaning growth rate QTL 1 (mouse)					2	118589253	160611165	Mouse
12910814	Pwbwq1_m	pre-weaning body weight QTL 1 (mouse)					2	118589253	160611165	Mouse
11532731	Sluc31a_m	susceptibility to lung cancer 31a (mouse)					2	88015003	122015170	Mouse
12904935	Edlmmq2_m	extensor digitorum longus muscle mass QTL 2 (mouse)					2	97210364	131210364	Mouse
12904954	Gmmq2_m	gastrocnemius muscle mass QTL 2 (mouse)					2	97210364	131210364	Mouse
12904007	Cfq7_m	conditioned fear QTL 7 (mouse)					2	118356772	125048872	Mouse
13506762	Tbvq2_m	trabecular bone volume QTL 2 (mouse)					2	115430481	124741920	Mouse
13824983	Vclq1_m	curvilinear velocity QTL 1 (mouse)					2	61830344	136841920	Mouse
27226761	Feml18_m	femur length 18, 16 week (mouse)					2	94230345	154241920	Mouse
27226788	Feml13_m	femur length 13, 10 week (mouse)					2	102630345	159941920	Mouse

Markers in Region

AV304093

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	2	119,135,721 - 119,135,861	UniSTS	GRCm38
MGSCv37	2	118,961,457 - 118,961,597	UniSTS	GRCm37
Celera	2	120,286,252 - 120,286,392	UniSTS
Cytogenetic Map	2	F1	UniSTS
cM Map	2	66.8	UniSTS
Whitehead/MRC_RH	2	1525.24	UniSTS

RH125939

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	7	116,018,956 - 116,019,166	UniSTS	GRCm38
GRCm38	2	119,135,744 - 119,135,960	UniSTS	GRCm38
MGSCv37	7	123,162,470 - 123,162,680	UniSTS	GRCm37
MGSCv37	2	118,961,480 - 118,961,696	UniSTS	GRCm37
Celera	2	120,286,275 - 120,286,491	UniSTS
Celera	7	115,966,033 - 115,966,249	UniSTS
Cytogenetic Map	7	F1	UniSTS
Cytogenetic Map	2	F1	UniSTS
cM Map	7	55.0	UniSTS
cM Map	2	66.8	UniSTS

Rad51

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	2	119,135,132 - 119,135,316	UniSTS	GRCm38
MGSCv37	2	118,960,868 - 118,961,052	UniSTS	GRCm37
Celera	2	120,285,663 - 120,285,847	UniSTS
Cytogenetic Map	2	F1	UniSTS
cM Map	2	66.8	UniSTS

Rad51

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	2	F1	UniSTS
cM Map	2	66.8	UniSTS

Rad51

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	2	F1	UniSTS
cM Map	2	66.8	UniSTS

Rad51

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	2	F1	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_011234	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_156017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AI592821	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK011242	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK045050	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK076468	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK148165	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK151157	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK151177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK160282	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK208342	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL772264	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC027384	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC058214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466519	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D13473	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D13803	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000028795 ⟹ ENSMUSP00000028795

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	2	118,943,288 - 118,967,771 (+)	Ensembl
GRCm38.p6 Ensembl	2	119,112,807 - 119,137,290 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000110828

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	2	118,943,295 - 118,964,080 (+)	Ensembl
GRCm38.p6 Ensembl	2	119,112,814 - 119,133,599 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000140939 ⟹ ENSMUSP00000119444

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	2	118,943,274 - 118,954,327 (+)	Ensembl
GRCm38.p6 Ensembl	2	119,112,793 - 119,123,846 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000141389

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	2	118,949,177 - 118,952,743 (+)	Ensembl
GRCm38.p6 Ensembl	2	119,118,696 - 119,122,262 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000143934

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	2	118,964,643 - 118,965,689 (+)	Ensembl
GRCm38.p6 Ensembl	2	119,134,162 - 119,135,208 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000151406 ⟹ ENSMUSP00000117939

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	2	118,954,284 - 118,977,926 (+)	Ensembl
GRCm38.p6 Ensembl	2	119,123,803 - 119,147,445 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000152327 ⟹ ENSMUSP00000119101

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	2	118,943,298 - 118,967,518 (+)	Ensembl
GRCm38.p6 Ensembl	2	119,112,817 - 119,137,037 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000154683

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	2	118,961,999 - 118,964,936 (+)	Ensembl
GRCm38.p6 Ensembl	2	119,131,518 - 119,134,455 (+)	Ensembl

RefSeq Acc Id:

NM_011234 ⟹ NP_035364

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	2	118,943,295 - 118,966,554 (+)	NCBI
GRCm38	2	119,112,814 - 119,136,073 (+)	NCBI
MGSCv37	2	118,938,553 - 118,961,806 (+)	RGD
Celera	2	120,265,474 - 120,286,601 (+)	RGD
cM Map	2		ENTREZGENE

Sequence:

show sequence

TGAGGATTTGGCGGGATTTCCGAAAGTCGCGCGCCGTGCGCAGATCCGCGCCTGGGCAAAGCCG
AGGCGCTCCCACAGGTGTGGCCAGGAAGACTGAAATTTTTCGTAGAAAACCTGACAGAGGAGCA
ACGAAGCGCGTTCGAGCCGGGTGAAGTGGGGGGAGTGTGGTGTGTGCAGAGCCGGCTGCCCGGA
GGAGCGAGCGGCCCGTGGCCGCGGGACAGTCATGGCTATGCAAATGCAGCTTGAAGCAAGTGCA
GATACTTCAGTGGAAGAAGAAAGTTTTGGTCCACAGCCTATTTCACGGTTAGAGCAGTGTGGCA
TAAATGCCAATGATGTGAAGAAATTAGAAGAAGCCGGTTACCATACAGTGGAGGCTGTTGCTTA
TGCACCGAAGAAGGAACTAATAAATATTAAGGGAATTAGTGAAGCCAAAGCTGACAAAATTCTG
ACTGAGGCAGCAAAATTGGTTCCAATGGGTTTCACCACGGCAACTGAGTTTCACCAGCGCCGGT
CAGAGATCATACAGATAACTACTGGCTCCAAAGAGCTGGACAAGCTGCTTCAAGGTGGAATTGA
GACTGGATCTATCACAGAGATGTTTGGAGAATTCCGAACTGGGAAGACACAGATCTGTCATACG
TTGGCTGTTACATGCCAGCTCCCCATTGACCGTGGTGGAGGTGAAGGGAAGGCCATGTACATTG
ACACCGAGGGCACCTTTAGGCCGGAGCGGCTGCTAGCAGTAGCTGAGAGATACGGTCTCTCTGG
CAGCGATGTCCTAGATAATGTAGCATATGCGCGAGGGTTCAACACAGACCACCAGACCCAGCTC
CTTTACCAAGCGTCAGCCATGATGGTAGAATCCAGGTATGCACTGCTTATTGTAGACAGTGCTA
CTGCCCTTTACAGAACAGACTACTCAGGGCGGGGAGAGCTTTCAGCCAGGCAAATGCATTTGGC
CAGATTTCTGAGGATGCTGCTTCGACTTGCTGATGAGTTTGGTGTCGCAGTGGTAATCACCAAC
CAGGTAGTAGCCCAAGTAGATGGAGCAGCCATGTTCGCTGCAGATCCCAAAAAACCCATTGGAG
GGAACATCATCGCTCATGCGTCAACCACCAGGCTGTACCTGAGAAAAGGAAGAGGGGAGACCAG
AATCTGCAAAATCTATGACTCTCCCTGTCTTCCTGAAGCTGAAGCTATGTTTGCCATTAATGCA
GATGGAGTGGGCGATGCCAAAGACTGACTCCTTAGGCTTTCTTTCCTGTGATGCTATACGGCTT
TTCTAAATGCTCTACAGCTAATGGAGAGGACTGTGTACTGGGCTTCTTCACAGGCTCATGTTGT
GACTGCCCCGCATGGCTTCCGGGAAAACAACTATTGTATCAGCTCTCTGGTAGCAGAAACACAT
CTGATCTGAAAGGTTTCCTGTAGAGTCTATTAATAACTGATTTCTTTGGTGTTTAGAGGAGAAG
TATGAAATAGCAGGTGTGGGGCAGTCTTTTGTCTTCAGGAGAAGTAAACTGGAAAGATCCGAGT
ACTCTCACTTCTCAAGGATGGTAAACTAAATGCCTGAGGATCTGTAAGTGGGAATGGGTGGTTT
ACACATTCTTTTCTCTGTAAGACAGATGCAAACTTAGTTATATGCCTGAACTGTCACATCATTT
TAAAATTTATTTTTGATTAAGGAGTCTTACATGCAGCATGCTAGACTACGATCCCTGCATGCTT
GTTCTCTAAATTACTAAGACTTCACTTAAGGAAATTTGTTCTGCTGCTAATAAAGTAGTTGTGT
GCAGTGGATGTGTTATTTGCTGGAGATATTCTAGTGCAAACTGAATATTGCAAAACAGGGTTTC
TATAACAGCTTTCGGTACTGTGTTGTTCGTTATGGTCAGCTGCAGTTGTAAAGTGTGAACCTGA
AAGAAAGCCCAGCATTCAGGTTACTGCATTGTAGCCTTTGGCCGAAGAATAAGAACCCCAGGCT
GGTTTACTGTATCTTTCCTGTGGTCTTTGTTTTTATTGTATAAGTTTTGTGTTGCAGAGGTCTG
ACATTACTCAAATAACTCTACATCAGGAGTATTTCCAAAAACTATAGTCTTCTTTTGAGTCATT
GAGTCTCATTATTAAAAGAATTTCAAAACAGA

hide sequence

RefSeq Acc Id:

NR_156017

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	2	118,943,295 - 118,966,554 (+)	NCBI
GRCm38	2	119,112,814 - 119,136,073 (+)	NCBI

Sequence:

show sequence

TGAGGATTTGGCGGGATTTCCGAAAGTCGCGCGCCGTGCGCAGATCCGCGCCTGGGCAAAGCCG
AGGCGCTCCCACAGGTGTGGCCAGGAAGACTGAAATTTTTCGTAGAAAACCTGACAGAGGAGCA
ACGAAGCGCGTTCGAGCCGGGTGAAGTGGGGGGAGTGTGGTGTGTGCAGAGCCGGCTGCCCGGA
GGAGCGAGCGGCCCGTGGCCGCGGGACAGTCATGGCTATGCAAATGCAGCTTGAAGCAAGTGCA
GATACTTCAGTGGAAGAAGAAAGTTTTGGTCCACAGCCTATTTCACGGTTAGAGCAGTGTGGCA
TAAATGCCAATGATGTGAAGAAATTAGAAGAAGCCGGTTACCATACAGTGGAGGCTGTTGCTTA
TGCACCGAAGAAGGAACTAATAAATATTAAGGGAATTAGTGAAGCCAAAGCTGACAAAATTCTG
ACTGAGGCAGCAAAATTGGTTCCAATGGGTTTCACCACGGCAACTGAGTTTCACCAGCGCCGGT
CAGAGATCATACAGATAACTACTGGCTCCAAAGAGCTGGACAAGCTGCTTCAAGGTGGAATTGA
GACTGGATCTATCACAGAGATGTTTGGAGAATTCCGAACTGGGAAGACACAGATCTGTCATACG
TTGGCTGTTACATGCCAGCTCCCCATTGACCGTGGTGGAGGTGAAGGGAAGGCCATGTACATTG
ACACCGAGGGCACCTTTAGGCCGGAGCGGCTGCTAGCAGTAGCTGAGAGATACGGTCTCTCTGG
CAGCGATGTCCTAGATAATGTAGCATATGCGCGAGGGTTCAACACAGACCACCAGACCCAGCTC
CTTTACCAAGCGTCAGCCATGATGGTAGAATCCAGTTTGGTGTCGCAGTGGTAATCACCAACCA
GGTAGTAGCCCAAGTAGATGGAGCAGCCATGTTCGCTGCAGATCCCAAAAAACCCATTGGAGGG
AACATCATCGCTCATGCGTCAACCACCAGGCTGTACCTGAGAAAAGGAAGAGGGGAGACCAGAA
TCTGCAAAATCTATGACTCTCCCTGTCTTCCTGAAGCTGAAGCTATGTTTGCCATTAATGCAGA
TGGAGTGGGCGATGCCAAAGACTGACTCCTTAGGCTTTCTTTCCTGTGATGCTATACGGCTTTT
CTAAATGCTCTACAGCTAATGGAGAGGACTGTGTACTGGGCTTCTTCACAGGCTCATGTTGTGA
CTGCCCCGCATGGCTTCCGGGAAAACAACTATTGTATCAGCTCTCTGGTAGCAGAAACACATCT
GATCTGAAAGGTTTCCTGTAGAGTCTATTAATAACTGATTTCTTTGGTGTTTAGAGGAGAAGTA
TGAAATAGCAGGTGTGGGGCAGTCTTTTGTCTTCAGGAGAAGTAAACTGGAAAGATCCGAGTAC
TCTCACTTCTCAAGGATGGTAAACTAAATGCCTGAGGATCTGTAAGTGGGAATGGGTGGTTTAC
ACATTCTTTTCTCTGTAAGACAGATGCAAACTTAGTTATATGCCTGAACTGTCACATCATTTTA
AAATTTATTTTTGATTAAGGAGTCTTACATGCAGCATGCTAGACTACGATCCCTGCATGCTTGT
TCTCTAAATTACTAAGACTTCACTTAAGGAAATTTGTTCTGCTGCTAATAAAGTAGTTGTGTGC
AGTGGATGTGTTATTTGCTGGAGATATTCTAGTGCAAACTGAATATTGCAAAACAGGGTTTCTA
TAACAGCTTTCGGTACTGTGTTGTTCGTTATGGTCAGCTGCAGTTGTAAAGTGTGAACCTGAAA
GAAAGCCCAGCATTCAGGTTACTGCATTGTAGCCTTTGGCCGAAGAATAAGAACCCCAGGCTGG
TTTACTGTATCTTTCCTGTGGTCTTTGTTTTTATTGTATAAGTTTTGTGTTGCAGAGGTCTGAC
ATTACTCAAATAACTCTACATCAGGAGTATTTCCAAAAACTATAGTCTTCTTTTGAGTCATTGA
GTCTCATTATTAAAAGAATTTCAAAACAGAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_035364	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH27384	(Get FASTA)	NCBI Sequence Viewer
	BAA02718	(Get FASTA)	NCBI Sequence Viewer
	BAA02961	(Get FASTA)	NCBI Sequence Viewer
	BAB27489	(Get FASTA)	NCBI Sequence Viewer
	BAC36357	(Get FASTA)	NCBI Sequence Viewer
	BAE30162	(Get FASTA)	NCBI Sequence Viewer
	BAE30179	(Get FASTA)	NCBI Sequence Viewer
	EDL27935	(Get FASTA)	NCBI Sequence Viewer
	EDL27936	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000028795
	ENSMUSP00000028795.4
	ENSMUSP00000117939.2
	ENSMUSP00000119101.2
	ENSMUSP00000119444.2
GenBank Protein	Q08297	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_035364 ⟸ NM_011234

- UniProtKB:

Q3UAY5 (UniProtKB/Swiss-Prot), Q08297 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MAMQMQLEASADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGYHTVEAVAYAPKKELINIK
GISEAKADKILTEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGE
FRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYA
RGFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLA
DEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCL
PEAEAMFAINADGVGDAKD

hide sequence

RefSeq Acc Id:

ENSMUSP00000119101 ⟸ ENSMUST00000152327

RefSeq Acc Id:

ENSMUSP00000028795 ⟸ ENSMUST00000028795

RefSeq Acc Id:

ENSMUSP00000117939 ⟸ ENSMUST00000151406

RefSeq Acc Id:

ENSMUSP00000119444 ⟸ ENSMUST00000140939

Protein Domains

HhH RecA family profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q08297-F1-model_v2	AlphaFold	Q08297	1-339	view protein structure

Promoters

RGD ID:

6832243

Promoter ID:

MM_KWN:31210

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

ENSMUST00000110828, OTTMUST00000037427, OTTMUST00000037428, OTTMUST00000037430

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	2	118,938,111 - 118,938,611 (+)	MPROMDB

RGD ID:

6832244

Promoter ID:

MM_KWN:31214

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

BoneMarrow_2Hour, BoneMarrow_4Hour

Transcripts:

OTTMUST00000037433

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	2	118,959,921 - 118,960,421 (+)	MPROMDB

RGD ID:

6878326

Promoter ID:

EPDNEW_M2614

Type:

initiation region

Name:

Rad51_1

Description:

Mus musculus RAD51 recombinase , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	2	119,112,855 - 119,112,915	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:97890	AgrOrtholog
Ensembl Genes	ENSMUSG00000027323	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000028795	ENTREZGENE
	ENSMUST00000028795.10	UniProtKB/Swiss-Prot
	ENSMUST00000140939.8	UniProtKB/TrEMBL
	ENSMUST00000151406.2	UniProtKB/TrEMBL
	ENSMUST00000152327.8	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	5' to 3' exonuclease, C-terminal subdomain	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	AAA+_ATPase	UniProtKB/Swiss-Prot
	DNA_recomb/repair_Rad51	UniProtKB/Swiss-Prot
	DNA_recomb/repair_Rad51_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	DNA_recomb/repair_RecA-like	UniProtKB/Swiss-Prot
	DNA_repair_Rad51/TF_NusA_a-hlx	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RecA_ATP-bd	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RecA_monomer-monomer_interface	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:19361	UniProtKB/Swiss-Prot
MGD	MGI:97890	ENTREZGENE
NCBI Gene	19361	ENTREZGENE
PANTHER	DNA REPAIR PROTEIN RAD51 HOMOLOG 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	HHH_5	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Rad51	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Rad51	PhenoGen
PIRSF	Rad51	UniProtKB/Swiss-Prot
PROSITE	RECA_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RECA_3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	AAA	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF47794	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF52540	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A3KGI2_MOUSE	UniProtKB/TrEMBL
	D6RCK1_MOUSE	UniProtKB/TrEMBL
	F7AT35_MOUSE	UniProtKB/TrEMBL
	Q08297	ENTREZGENE
	Q3UAY5	ENTREZGENE
	RAD51_MOUSE	UniProtKB/Swiss-Prot
UniProt Secondary	Q3UAY5	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-29	Rad51	RAD51 recombinase		RAD51 homolog	Symbol and/or name change	5135510	APPROVED
2012-12-25	Rad51	RAD51 homolog		RAD51 homolog (S. cerevisiae)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

Mammalian Phenotype

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

Mammalian Phenotype