Gene: Hspa8 (heat shock protein 8)  Mus musculus Symbol: Hspa8 Name: heat shock protein 8 Description: ENCODES a protein that exhibits ATPase activity, coupled; unfolded protein binding; ADP binding (ortholog); INVOLVED IN ATP catabolic process; chaperone mediated protein folding requiring cofactor; protein folding; PARTICIPATES IN androgen signaling pathway; antigen processing and presentation pathway; endocytosis pathway; ASSOCIATED WITH Huntington Disease; Inflammatory Bowel Diseases; Myocardial Reperfusion Injury; FOUND IN cytosol; extracellular vesicular exosome; intracellular; INTERACTS WITH (2,4,5-trichlorophenoxy)acetic acid; (S)-amphetamine; 17alpha-ethynylestradiol Type: protein-coding RefSeq Status: PROVISIONAL Also known as: 2410008N15Rik; heat shock 70 kDa protein 8; heat shock 70kD protein 8; heat shock cognate 71 kDa protein; heat shock cognate hsc73; heat shock protein cognate 70; Hsc70; Hsc71; Hsc73; Hsp73; Hspa10; MGC102007; MGC106514; MGC118485; OTTMUSP00000039133; OTTMUSP00000039134 Orthologs: Homo sapiens : HSPA8 (heat shock 70kDa protein 8)  HGNC Rattus norvegicus : Hspa8 (heat shock 70kDa protein 8) Related Pseudogenes: Gm13854   Gm15459   Gm15604   Gm17976   Gm18069   Gm5575   Gm6210   Gm7048   Gm7232   Gm7899   Gm8141   Gm8326   Gm8337   Gm8355   Gm9436   Latest Assembly: Mouse Genome Assembly Build 37 Position: Map Chr Position Strand Source Mouse Genome Assembly GRCm38 9 40,801,273 - 40,805,199 + NCBI Mouse cM Map 9 21.55   NCBI Mouse Celera Assembly 9 38,034,609 - 38,038,251 + NCBI Mouse Genome Assembly Build 37 9 40,609,356 - 40,613,282 + NCBI Mouse Genome Assembly Build 36.1 9 40,609,356 - 40,613,282 + NCBI Mouse Cytogenetic Map 9 A5.1   NCBI Model Launch Genome Browser (GBrowse) Annotation    (Toggle Detail/Summary View) Disease Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) Acute Kidney Injury   ISS RGD:621725 7242786   RGD   Brain Ischemia   ISS RGD:621725 6480229   RGD   Colorectal Neoplasms Disease_progression ISS RGD:736219 6480104 protein: increased expression: serum RGD   Diabetic Nephropathies   ISS RGD:736219 7242762   RGD   Graft vs Host Disease   ISS RGD:621725 7242787   RGD   Huntington Disease   IEP   5688778 protein: increased expression RGD   Hypertension   ISS RGD:736219 6480224 mRNA: increased expression: leukocyte RGD   Hypertension, Renal   ISS RGD:736219 7242785 DNA: snp: 5'utr: -110A>C RGD   Inflammatory Bowel Diseases   IEP   6218980   RGD   Kidney Reperfusion Injury   ISS RGD:621725 7242788   RGD   Macular Degeneration   ISS RGD:736219 6478714 mRNA: increased expression: white blood cells RGD   Metabolic Diseases   ISS RGD:621725 4142786 protein: increased expression: kidney: poly-D-glutamic acid induced acute lysosomal thesaurismosis RGD   Multiple Sclerosis   ISS RGD:736219 6480236 protein: increased expression: cerebrospinal fluid RGD   Multiple Sclerosis, Relapsing-Remitting   ISS RGD:736219 5688780 protein: increased expression RGD   Myocardial Reperfusion Injury   IPM   6480208   RGD   Myocarditis   IPM   6480208   RGD   Parkinson Disease   ISS RGD:736219 6218982 protein: decreased expression RGD   Parkinson Disease   ISS RGD:621725 6480228 protein: increased expression: brain RGD   Parkinson Disease   ISS RGD:736219 6480203   RGD   Uterine Cervical Neoplasms   ISS RGD:736219 6218976 Protein: increased expression RGD   Gene-Chemical Interaction Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) (2,4,5-trichlorophenoxy)acetic acid decreases expression EXP   6480464 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of HSPA8 mRNA CTD PMID:18579281 (R)-adrenaline increases expression ISO RGD:621725 6480464 Epinephrine results in increased expression of HSPA8 protein CTD PMID:19464573 (S)-amphetamine increases expression EXP   6480464 Dextroamphetamine results in increased expression of HSPA8 mRNA CTD PMID:12205029 (S)-amphetamine multiple interactions EXP   6480464 SOD1 inhibits the reaction [Dextroamphetamine results in increased expression of HSPA8 mRNA] CTD PMID:12205029 1-naphthyl isothiocyanate increases expression ISO RGD:621725 6480464 1-Naphthylisothiocyanate results in increased expression of HSPA8 mRNA CTD PMID:20551477 17alpha-ethynylestradiol multiple interactions EXP   6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HSPA8 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression EXP   6480464 Ethinyl Estradiol results in increased expression of HSPA8 mRNA CTD PMID:17942748 PMID:16174780 17alpha-ethynylestradiol increases expression ISO RGD:621725 6480464 Ethinyl Estradiol results in increased expression of HSPA8 mRNA CTD PMID:16174780 17alpha-ethynylestradiol increases expression EXP   6480464 Ethinyl Estradiol results in increased expression of HSPA8 mRNA CTD PMID:16174780 PMID:17942748 17alpha-ethynylestradiol affects expression EXP   6480464 Ethinyl Estradiol affects the expression of HSPA8 mRNA CTD PMID:17555576 17beta-estradiol increases expression ISO RGD:736219 6480464 Estradiol results in increased expression of HSPA8 mRNA CTD PMID:16514628 PMID:20106945 17beta-estradiol affects expression ISO RGD:736219 6480464 Estradiol affects the expression of HSPA8 mRNA CTD PMID:22574217 17beta-estradiol increases expression ISO RGD:736219 6480464 Estradiol results in increased expression of HSPA8 mRNA CTD PMID:20106945 PMID:16514628 1H-pyrazole increases expression EXP   6480464 pyrazole results in increased expression of HSPA8 mRNA CTD PMID:17945193 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP   6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HSPA8 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP   6480464 Tetrachlorodibenzodioxin affects the expression of HSPA8 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:621725 6480464 Tetrachlorodibenzodioxin affects the expression of HSPA8 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP   6480464 Tetrachlorodibenzodioxin results in increased expression of HSPA8 mRNA CTD PMID:17942748 PMID:16467188 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:621725 6480464 Tetrachlorodibenzodioxin results in increased expression of HSPA8 protein CTD PMID:19201780 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:621725 6480464 Tetrachlorodibenzodioxin results in decreased expression of HSPA8 protein CTD PMID:16548065 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP   6480464 Tetrachlorodibenzodioxin results in increased expression of HSPA8 mRNA CTD PMID:16467188 PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:621725 6480464 Tetrachlorodibenzodioxin results in decreased expression of HSPA8 mRNA CTD PMID:11752688 2,4,6-trinitrotoluene affects expression ISO RGD:621725 6480464 Trinitrotoluene affects the expression of HSPA8 mRNA CTD PMID:21346803 2,4-dinitrotoluene affects expression ISO RGD:621725 6480464 2,4-dinitrotoluene affects the expression of HSPA8 mRNA CTD PMID:21346803 2-methylcholine affects expression ISO RGD:736219 6480464 beta-methylcholine affects the expression of HSPA8 mRNA CTD PMID:21179406 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine affects localization ISO RGD:621725 6480464 Puromycin Aminonucleoside affects the localization of HSPA8 protein CTD PMID:1614035 3,4-methylenedioxymethamphetamine decreases expression EXP   6480464 N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of HSPA8 mRNA CTD PMID:20188158 5-aza-2'-deoxycytidine increases expression ISO RGD:736219 6480464 decitabine results in increased expression of HSPA8 mRNA CTD PMID:19151715 5-aza-2'-deoxycytidine affects methylation ISO RGD:736219 6480464 decitabine affects the methylation of HSPA8 gene CTD PMID:17630775 5-fluorouracil affects response to substance ISO RGD:736219 6480464 HSPA8 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 7,12-dimethyltetraphene increases expression EXP   6480464 9,10-Dimethyl-1,2-benzanthracene results in increased expression of HSPA8 mRNA CTD PMID:21785161 7H-xanthine multiple interactions ISO RGD:621725 6480464 [Xanthine co-treated with XDH protein] results in decreased expression of HSPA8 protein CTD PMID:19464573 8-bromo-3',5'-cyclic AMP decreases expression ISO RGD:736219 6480464 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of HSPA8 mRNA CTD PMID:22079614 9H-xanthine multiple interactions ISO RGD:621725 6480464 [Xanthine co-treated with XDH protein] results in decreased expression of HSPA8 protein CTD PMID:19464573 acrylamide decreases expression ISO RGD:621725 6480464 Acrylamide results in decreased expression of HSPA8 protein CTD PMID:15081597 acrylamide multiple interactions ISO RGD:621725 6480464 Tacrolimus inhibits the reaction [Acrylamide results in decreased expression of HSPA8 protein] CTD PMID:15081597 afimoxifene decreases expression ISO RGD:736219 6480464 4-hydroxytamoxifen results in decreased expression of HSPA8 mRNA CTD PMID:16514628 albendazole multiple interactions ISO RGD:736219 6480464 [Ivermectin co-treated with Albendazole] results in increased expression of HSPA8 mRNA CTD PMID:16861626 all-trans-retinoic acid decreases expression ISO RGD:736219 6480464 Tretinoin results in decreased expression of HSPA8 mRNA CTD PMID:17218384 ammonium chloride affects expression ISO RGD:621725 6480464 Ammonium Chloride affects the expression of HSPA8 mRNA CTD PMID:16483693 apigenin decreases expression EXP   6480464 Apigenin results in decreased expression of HSPA8 mRNA; more ... CTD PMID:22359648 Aroclor 1254 increases expression ISO RGD:736219 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of HSPA8 mRNA CTD PMID:17851650 arsenic atom multiple interactions EXP   6480464 [APOE protein affects the susceptibility to Arsenic] which results in increased expression of HSPA8 mRNA CTD PMID:22719926 arsenic atom increases expression EXP   6480464 Arsenic results in increased expression of HSPA8 mRNA CTD PMID:22956628 arsenite(3-) increases oxidation ISO RGD:736219 6480464 arsenite results in increased oxidation of HSPA8 protein CTD PMID:20196163 astemizole increases expression ISO RGD:621725 6480464 Astemizole results in increased expression of HSPA8 mRNA CTD PMID:20221588 bathocuproine disulfonic acid multiple interactions ISO RGD:736219 6480464 [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HSPA8 mRNA; more ... CTD PMID:15477007 benzene increases expression ISO RGD:736219 6480464 Benzene results in increased expression of HSPA8 mRNA CTD PMID:21843810 benzo[a]pyrene multiple interactions EXP   6480464 [Benzo(a)pyrene co-treated with XPA gene mutant form co-treated with TRP53 gene mutant form] results in decreased expression of HSPA8 mRNA CTD PMID:21715664 benzo[a]pyrene increases expression EXP   6480464 Benzo(a)pyrene results in increased expression of HSPA8 mRNA CTD PMID:21569818 PMID:22342234 benzo[a]pyrene increases expression EXP   6480464 Benzo(a)pyrene results in increased expression of HSPA8 mRNA CTD PMID:21569818 benzo[a]pyrene increases expression ISO RGD:736219 6480464 Benzo(a)pyrene results in increased expression of HSPA8 mRNA CTD PMID:20498004 bifenthrin decreases expression ISO RGD:736219 6480464 bifenthrin results in decreased expression of HSPA8 protein CTD PMID:16271832 bis(2-ethylhexyl) phthalate increases expression ISO RGD:621725 6480464 Diethylhexyl Phthalate results in increased expression of HSPA8 mRNA CTD PMID:21318169 bis(2-ethylhexyl) phthalate increases expression EXP   6480464 Diethylhexyl Phthalate results in increased expression of HSPA8 mRNA CTD PMID:21318169 bisphenol A increases expression ISO RGD:621725 6480464 bisphenol A results in increased expression of HSPA8 protein CTD PMID:15229138 bromobenzene affects binding ISO RGD:621725 6480464 bromobenzene metabolite binds to HSPA8 protein CTD PMID:17305373 C60 fullerene increases expression ISO RGD:621725 6480464 fullerene C60 results in increased expression of HSPA8 mRNA CTD PMID:19167457 cadmium dichloride increases expression EXP   6480464 Cadmium Chloride results in increased expression of HSPA8 mRNA CTD PMID:15081267 cadmium sulfate increases expression ISO RGD:736219 6480464 cadmium sulfate results in increased expression of HSPA8 mRNA CTD PMID:21783983 chloroprene increases expression EXP   6480464 Chloroprene results in increased expression of HSPA8 mRNA CTD PMID:23125180 chlorpyrifos decreases expression EXP   6480464 Chlorpyrifos results in decreased expression of HSPA8 mRNA CTD PMID:20350560 choline multiple interactions EXP   6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of HSPA8 gene CTD PMID:20938992 ciguatoxin CTX1B affects expression EXP   6480464 Ciguatoxins affects the expression of HSPA8 mRNA CTD PMID:18353800 cisplatin increases expression ISO RGD:736219 6480464 Cisplatin results in increased expression of HSPA8 protein CTD PMID:21924258 cobalt dichloride increases expression ISO RGD:621725 6480464 cobaltous chloride results in increased expression of HSPA8 mRNA CTD PMID:7626009 cobalt dichloride increases expression ISO RGD:736219 6480464 cobaltous chloride results in increased expression of HSPA8 mRNA CTD PMID:19320972 copper atom multiple interactions ISO RGD:736219 6480464 [Copper binds to N'-((2-hydroxyphenyl)carbonothioyl)pyridine-2-carbohydrazide] which results in increased expression of HSPA8 protein CTD PMID:16600465 copper atom affects binding ISO RGD:736219 6480464 HSPA8 protein binds to Copper CTD PMID:14534351 PMID:15359738 copper atom affects binding ISO RGD:736219 6480464 HSPA8 protein binds to Copper CTD PMID:15359738 copper atom increases expression ISO RGD:736219 6480464 Copper results in increased expression of HSPA8 mRNA CTD PMID:16629173 copper(0) multiple interactions ISO RGD:736219 6480464 [Copper binds to N'-((2-hydroxyphenyl)carbonothioyl)pyridine-2-carbohydrazide] which results in increased expression of HSPA8 protein CTD PMID:16600465 copper(0) affects binding ISO RGD:736219 6480464 HSPA8 protein binds to Copper CTD PMID:14534351 PMID:15359738 copper(0) affects binding ISO RGD:736219 6480464 HSPA8 protein binds to Copper CTD PMID:15359738 copper(0) increases expression ISO RGD:736219 6480464 Copper results in increased expression of HSPA8 mRNA CTD PMID:16629173 copper(2+) sulfate increases expression ISO RGD:736219 6480464 Copper Sulfate results in increased expression of HSPA8 mRNA CTD PMID:20599845 copper(2+) sulfate decreases expression EXP   6480464 Copper Sulfate results in decreased expression of HSPA8 mRNA CTD PMID:18579281 copper(2+) sulfate affects expression ISO RGD:736219 6480464 Copper Sulfate affects the expression of HSPA8 mRNA CTD PMID:19549813 copper(2+) sulfate decreases expression ISO RGD:736219 6480464 Copper Sulfate results in decreased expression of HSPA8 mRNA CTD PMID:20599845 cyclophosphamide affects response to substance ISO RGD:736219 6480464 HSPA8 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 cyclosporin A increases expression ISO RGD:736219 6480464 Cyclosporine results in increased expression of HSPA8 mRNA CTD PMID:20106945 dasatinib (anhydrous) affects binding ISO RGD:736219 6480464 dasatinib binds to HSPA8 protein CTD PMID:18180381 Delta(9)-tetrahydrocannabinol decreases expression EXP   6480464 Tetrahydrocannabinol results in decreased expression of HSPA8 mRNA; more ... CTD PMID:18584336 Delta(9)-tetrahydrocannabinol decreases expression ISO RGD:736219 6480464 Tetrahydrocannabinol results in decreased expression of HSPA8 mRNA CTD PMID:16039398 PMID:18454173 Delta(9)-tetrahydrocannabinol decreases expression ISO RGD:736219 6480464 Tetrahydrocannabinol results in decreased expression of HSPA8 mRNA CTD PMID:18454173 PMID:16039398 dexamethasone increases expression EXP   6480464 Dexamethasone results in increased expression of HSPA8 mRNA CTD PMID:17998272 diarsenic trioxide increases expression ISO RGD:736219 6480464 arsenic trioxide results in increased expression of HSPA8 protein CTD PMID:19364129 diazoxide decreases expression EXP   6480464 Isoproterenol results in decreased expression of HSPA8 mRNA CTD PMID:20003209 dibutyl phthalate increases expression EXP   6480464 Dibutyl Phthalate results in increased expression of HSPA8 mRNA CTD PMID:21266533 diethyl maleate increases reduction EXP   6480464 diethyl maleate results in increased reduction of HSPA8 protein CTD PMID:19843705 dimethylarsinic acid decreases expression EXP   6480464 Cacodylic Acid results in decreased expression of HSPA8 mRNA CTD PMID:17441966 dimethylarsinic acid multiple interactions EXP   6480464 OGG1 protein inhibits the reaction [Cacodylic Acid results in decreased expression of HSPA8 mRNA] CTD PMID:17441966 disodium selenite increases expression ISO RGD:736219 6480464 Sodium Selenite results in increased expression of HSPA8 mRNA CTD PMID:18175754 diuron decreases expression ISO RGD:621725 6480464 Diuron results in decreased expression of HSPA8 mRNA CTD PMID:21551480 doxorubicin multiple interactions ISO RGD:736219 6480464 [Doxorubicin co-treated with pluronic block copolymer p85] results in increased expression of HSPA8 mRNA CTD PMID:16579640 doxorubicin increases expression ISO RGD:736219 6480464 Doxorubicin results in increased expression of HSPA8 mRNA CTD PMID:16579640 PMID:17680992 doxorubicin increases expression ISO RGD:736219 6480464 Doxorubicin results in increased expression of HSPA8 mRNA CTD PMID:17680992 PMID:16579640 fenofibrate increases expression EXP   6480464 Fenofibrate results in increased expression of HSPA8 mRNA CTD PMID:21318169 fenofibrate multiple interactions EXP   6480464 PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA8 mRNA] CTD PMID:21318169 ferric oxide multiple interactions EXP   6480464 [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of HSPA8 mRNA CTD PMID:20540983 folic acid multiple interactions EXP   6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of HSPA8 gene CTD PMID:20938992 formetanate decreases expression ISO RGD:736219 6480464 formetanate results in decreased expression of HSPA8 protein CTD PMID:16271832 fulvestrant decreases expression ISO RGD:736219 6480464 fulvestrant results in decreased expression of HSPA8 mRNA CTD PMID:16514628 furan affects binding ISO RGD:621725 6480464 furan binds to HSPA8 protein CTD PMID:22240984 furan increases expression EXP   6480464 furan results in increased expression of HSPA8 mRNA CTD PMID:20194422 gamma-poly(L-glutamic acid) macromolecule affects localization ISO RGD:621725 6480464 Polyglutamic Acid affects the localization of HSPA8 protein CTD PMID:10469394 hyaluronic acid multiple interactions ISO RGD:621725 6480464 Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of HSPA8 protein] CTD PMID:23178681 hyaluronic acid decreases expression ISO RGD:621725 6480464 Hyaluronic Acid analog results in decreased expression of HSPA8 protein CTD PMID:23178681 hydralazine multiple interactions ISO RGD:736219 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of HSPA8 mRNA CTD PMID:17183730 hydrogen peroxide affects expression ISO RGD:736219 6480464 Hydrogen Peroxide affects the expression of HSPA8 mRNA CTD PMID:21179406 hydrogen peroxide decreases expression ISO RGD:621725 6480464 Hydrogen Peroxide results in decreased expression of HSPA8 protein CTD PMID:23178681 hydrogen peroxide multiple interactions ISO RGD:621725 6480464 Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of HSPA8 protein] CTD PMID:23178681 hydroxyurea increases expression ISO RGD:736219 6480464 Hydroxyurea results in increased expression of HSPA8 mRNA CTD PMID:18647660 ibuprofen affects localization ISO RGD:736219 6480464 Ibuprofen affects the localization of HSPA8 protein CTD PMID:16239242 PMID:14706622 ibuprofen affects localization ISO RGD:736219 6480464 Ibuprofen affects the localization of HSPA8 protein CTD PMID:14706622 PMID:16239242 imipramine increases expression ISO RGD:621725 6480464 Imipramine results in increased expression of HSPA8 protein alternative form; more ... CTD PMID:10425221 indomethacin affects localization ISO RGD:736219 6480464 Indomethacin affects the localization of HSPA8 protein CTD PMID:16239242 PMID:14706622 indomethacin affects localization ISO RGD:736219 6480464 Indomethacin affects the localization of HSPA8 protein CTD PMID:14706622 PMID:16239242 indomethacin affects localization EXP   6480464 Indomethacin affects the localization of HSPA8 protein CTD PMID:14706622 ionomycin multiple interactions ISO RGD:736219 6480464 pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA]; more ... CTD PMID:15477007 iron atom multiple interactions ISO RGD:621725 6480464 [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of HSPA8 mRNA CTD PMID:22198552 isoprenaline decreases expression EXP   6480464 Isoproterenol results in decreased expression of HSPA8 mRNA CTD PMID:20003209 ivermectin multiple interactions ISO RGD:736219 6480464 [Ivermectin co-treated with Albendazole] results in increased expression of HSPA8 mRNA CTD PMID:16861626 L-methionine multiple interactions EXP   6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of HSPA8 gene CTD PMID:20938992 lead diacetate decreases expression EXP   6480464 lead acetate results in decreased expression of HSPA8 mRNA CTD PMID:21829687 lead diacetate affects expression EXP   6480464 lead acetate affects the expression of HSPA8 protein CTD PMID:20797405 lovastatin increases expression EXP   6480464 Lovastatin results in increased expression of HSPA8 mRNA CTD PMID:20493250 maneb multiple interactions EXP   6480464 [Paraquat co-treated with Maneb] results in increased expression of HSPA8 mRNA CTD PMID:18386188 manganese atom multiple interactions ISO RGD:736219 6480464 [Manganese binds to N'-((2-hydroxyphenyl)carbonothioyl)pyridine-2-carbohydrazide] which results in increased expression of HSPA8 protein CTD PMID:16600465 manganese(0) multiple interactions ISO RGD:736219 6480464 [Manganese binds to N'-((2-hydroxyphenyl)carbonothioyl)pyridine-2-carbohydrazide] which results in increased expression of HSPA8 protein CTD PMID:16600465 methamphetamine increases expression ISO RGD:621725 6480464 Methamphetamine results in increased expression of HSPA8 protein CTD PMID:19826936 methomyl decreases expression ISO RGD:736219 6480464 Methomyl results in decreased expression of HSPA8 protein CTD PMID:16271832 methotrexate affects expression EXP   6480464 Methotrexate affects the expression of HSPA8 mRNA CTD PMID:18502557 microcystin-LR increases expression EXP   6480464 cyanoginosin LR results in increased expression of HSPA8 mRNA CTD PMID:17654400 mitomycin C multiple interactions ISO RGD:736219 6480464 Mitomycin promotes the reaction [TP53 protein results in increased expression of HSPA8 mRNA] CTD PMID:18647660 mitomycin C increases expression ISO RGD:736219 6480464 Mitomycin results in increased expression of HSPA8 mRNA CTD PMID:18647660 monocrotaline multiple interactions EXP   6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA8 mRNA CTD PMID:21224054 morphine increases expression ISO RGD:621725 6480464 Morphine results in increased expression of HSPA8 mRNA CTD PMID:15497504 N-methylformamide increases expression EXP   6480464 methylformamide analog results in increased expression of HSPA8 mRNA; more ... CTD PMID:17040096 nickel atom multiple interactions ISO RGD:621725 6480464 [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of HSPA8 mRNA CTD PMID:22198552 nickel dichloride decreases expression ISO RGD:736219 6480464 nickel chloride results in decreased expression of HSPA8 mRNA CTD PMID:17312168 nitrofurantoin increases expression ISO RGD:621725 6480464 Nitrofurantoin results in increased expression of HSPA8 mRNA CTD PMID:7626009 ozone decreases expression EXP   6480464 Ozone results in decreased expression of HSPA8 mRNA CTD PMID:17095637 ozone increases expression EXP   6480464 Ozone results in increased expression of HSPA8 mRNA CTD PMID:21543283 paracetamol affects expression EXP   6480464 Acetaminophen affects the expression of HSPA8 mRNA CTD PMID:15606129 PMID:17562736 paracetamol increases expression ISO RGD:736219 6480464 Acetaminophen results in increased expression of HSPA8 mRNA CTD PMID:21420995 paracetamol multiple interactions EXP   6480464 PTGS2 protein affects the reaction [Acetaminophen results in increased expression of HSPA8 mRNA] CTD PMID:11743745 paracetamol increases expression EXP   6480464 Acetaminophen results in increased expression of HSPA8 mRNA CTD PMID:11743745 paracetamol affects expression EXP   6480464 Acetaminophen affects the expression of HSPA8 mRNA CTD PMID:17562736 PMID:15606129 paraquat multiple interactions EXP   6480464 [Paraquat co-treated with Maneb] results in increased expression of HSPA8 mRNA CTD PMID:18386188 perfluorooctane-1-sulfonic acid increases expression ISO RGD:621725 6480464 perfluorooctane sulfonic acid results in increased expression of HSPA8 mRNA CTD PMID:21318169 perfluorooctanoic acid increases expression ISO RGD:621725 6480464 perfluorooctanoic acid results in increased expression of HSPA8 mRNA CTD PMID:19162173 perfluorooctanoic acid increases expression ISO RGD:621725 6480464 perfluorooctanoic acid results in increased expression of HSPA8 mRNA CTD PMID:19162173 PMID:21318169 perfluorooctanoic acid increases expression ISO RGD:621725 6480464 perfluorooctanoic acid results in increased expression of HSPA8 mRNA CTD PMID:21318169 PMID:19162173 phenobarbital decreases expression ISO RGD:621725 6480464 Phenobarbital results in decreased expression of HSPA8 mRNA CTD PMID:19162173 phenobarbital affects expression EXP   6480464 Phenobarbital affects the expression of HSPA8 mRNA CTD PMID:23091169 phenytoin multiple interactions EXP   6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA8 mRNA CTD PMID:21224054 phlorizin increases expression EXP   6480464 Phlorhizin results in increased expression of HSPA8 mRNA CTD PMID:22538082 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:736219 6480464 bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA]] CTD PMID:15477007 phorone increases expression ISO RGD:621725 6480464 phorone results in increased expression of HSPA8 mRNA CTD PMID:7626009 pirimicarb decreases expression ISO RGD:736219 6480464 pirimicarb results in decreased expression of HSPA8 protein CTD PMID:16271832 pirinixic acid decreases expression EXP   6480464 pirinixic acid results in decreased expression of HSPA8 mRNA CTD PMID:17426115 pirinixic acid increases expression ISO RGD:621725 6480464 pirinixic acid results in increased expression of HSPA8 mRNA CTD PMID:21318169 PMID:19162173 pirinixic acid increases expression ISO RGD:621725 6480464 pirinixic acid results in increased expression of HSPA8 mRNA CTD PMID:19162173 PMID:21318169 pirinixic acid multiple interactions EXP   6480464 PPARA protein affects the reaction [pirinixic acid results in increased expression of HSPA8 mRNA] CTD PMID:21318169 pirinixic acid increases expression EXP   6480464 pirinixic acid results in increased expression of HSPA8 mRNA CTD PMID:21318169 pirinixic acid increases expression ISO RGD:621725 6480464 pirinixic acid results in increased expression of HSPA8 mRNA CTD PMID:19162173 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:621725 6480464 Pregnenolone Carbonitrile results in increased expression of HSPA8 mRNA CTD PMID:19162173 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:621725 6480464 Pregnenolone Carbonitrile results in increased expression of HSPA8 mRNA CTD PMID:19162173 PMID:21318169 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:621725 6480464 Pregnenolone Carbonitrile results in increased expression of HSPA8 mRNA CTD PMID:21318169 PMID:19162173 propiconazole increases expression EXP   6480464 propiconazole results in increased expression of HSPA8 mRNA CTD PMID:21278054 PMID:19363144 propiconazole increases expression EXP   6480464 propiconazole results in increased expression of HSPA8 mRNA CTD PMID:19363144 PMID:21278054 prostaglandin A1 increases metabolic processing EXP   6480464 prostaglandin A1 analog results in increased metabolism of HSPA8 protein CTD PMID:19800325 pyrogallol increases expression EXP   6480464 Pyrogallol results in increased expression of HSPA8 mRNA CTD PMID:20362636 pyrogallol multiple interactions EXP   6480464 Silymarin inhibits the reaction [Pyrogallol results in increased expression of HSPA8 mRNA] CTD PMID:20362636 quinolin-8-ol affects localization ISO RGD:736219 6480464 Oxyquinoline affects the localization of HSPA8 protein CTD PMID:16239242 raloxifene decreases expression ISO RGD:736219 6480464 Raloxifene results in decreased expression of HSPA8 mRNA CTD PMID:16514628 rifampicin multiple interactions EXP   6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA8 mRNA CTD PMID:21224054 S-butyl-DL-homocysteine (S,R)-sulfoximine increases expression ISO RGD:621725 6480464 Buthionine Sulfoximine results in increased expression of HSPA8 mRNA CTD PMID:7626009 S-butyl-DL-homocysteine (S,R)-sulfoximine increases expression EXP   6480464 Buthionine Sulfoximine results in increased expression of HSPA8 mRNA CTD PMID:15707499 sertraline increases expression ISO RGD:621725 6480464 Sertraline results in increased expression of HSPA8 protein alternative form; more ... CTD PMID:10425221 sevoflurane affects expression ISO RGD:621725 6480464 sevoflurane affects the expression of HSPA8 mRNA CTD PMID:15967596 silicon dioxide increases expression EXP   6480464 Silicon Dioxide results in increased expression of HSPA8 mRNA CTD PMID:19073995 simvastatin decreases expression ISO RGD:621725 6480464 Simvastatin results in decreased expression of HSPA8 protein CTD PMID:20217863 tacrolimus hydrate multiple interactions ISO RGD:621725 6480464 Tacrolimus inhibits the reaction [Acrylamide results in decreased expression of HSPA8 protein] CTD PMID:15081597 tacrolimus hydrate increases expression ISO RGD:621725 6480464 Tacrolimus results in increased expression of HSPA8 protein CTD PMID:15081597 tamoxifen affects expression EXP   6480464 Tamoxifen affects the expression of HSPA8 mRNA CTD PMID:17555576 trichloroethene increases expression ISO RGD:621725 6480464 Trichloroethylene results in increased expression of HSPA8 mRNA CTD PMID:14565619 trichloroethene decreases expression ISO RGD:621725 6480464 Trichloroethylene results in decreased expression of HSPA8 mRNA CTD PMID:19448997 troglitazone increases expression EXP   6480464 troglitazone results in increased expression of HSPA8 protein CTD PMID:18495193 tungsten atom multiple interactions ISO RGD:621725 6480464 [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of HSPA8 mRNA CTD PMID:22198552 valproic acid multiple interactions ISO RGD:736219 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of HSPA8 mRNA CTD PMID:17183730 valproic acid increases expression ISO RGD:621725 6480464 Valproic Acid results in increased expression of HSPA8 mRNA CTD PMID:21318169 zinc pyrithione increases expression ISO RGD:736219 6480464 zinc pyrithione results in increased expression of HSPA8 mRNA CTD PMID:21424779 zinc sulfate affects localization ISO RGD:736219 6480464 Zinc Sulfate affects the localization of HSPA8 protein CTD PMID:16239242 Gene Ontology Annotations Biological Process Term Qualifier Evidence With Reference Notes Source Original Reference(s) ATP catabolic process   IDA   2290270 MGI:MGI:2652284|PMID:12588994 GOC MGI:MGI:2652284 PMID:12588994 chaperone mediated protein folding requiring cofactor   IGI MGI:MGI:1931874 2290270 MGI:MGI:2681405|PMID:14644449 MGI MGI:MGI:2681405 PMID:14644449 chaperone mediated protein folding requiring cofactor   ISO UniProtKB:P63018 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 chaperone-mediated protein folding   ISO UniProtKB:P63018 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 mRNA processing   IEA UniProtKB-KW:KW-0507 2290270 MGI:MGI:1354194 UniProtKB MGI:MGI:1354194 negative regulation of transcription, DNA-dependent   ISO UniProtKB:P11142 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 protein folding   IDA   2290270 MGI:MGI:2652284|PMID:12588994 MGI MGI:MGI:2652284 PMID:12588994 regulation of cell cycle   IDA   2290270 MGI:MGI:2652284|PMID:12588994 MGI MGI:MGI:2652284 PMID:12588994 regulation of transcription, DNA-dependent   IEA UniProtKB-KW:KW-0805 2290270 MGI:MGI:1354194 UniProtKB MGI:MGI:1354194 response to stress   IEA UniProtKB-KW:KW-0346 2290270 MGI:MGI:1354194 UniProtKB MGI:MGI:1354194 RNA splicing   IEA UniProtKB-KW:KW-0508 2290270 MGI:MGI:1354194 UniProtKB MGI:MGI:1354194 transcription, DNA-dependent   IEA UniProtKB-KW:KW-0804 2290270 MGI:MGI:1354194 UniProtKB MGI:MGI:1354194 Cellular Component Term Qualifier Evidence With Reference Notes Source Original Reference(s) cell surface   ISO UniProtKB:P11142 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 cytoplasm   ISO UniProtKB:P63018 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 cytosol   IDA   2290270 MGI:MGI:3640843|PMID:16906134 MGI MGI:MGI:3640843 PMID:16906134 extracellular vesicular exosome   IDA   2290270 MGI:MGI:4367398|PMID:19724054 MGI MGI:MGI:4367398 PMID:19724054 extracellular vesicular exosome   ISO UniProtKB:P11142 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 extracellular vesicular exosome   ISO UniProtKB:P63018 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 intracellular   IDA   2290270 MGI:MGI:86714|PMID:9122205 MGI MGI:MGI:86714 PMID:9122205 neuron projection   ISO UniProtKB:P63018 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 neuronal cell body   ISO UniProtKB:P63018 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 nucleolus   ISO UniProtKB:P11142 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 nucleus   ISO UniProtKB:P11142 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 protein complex   ISO UniProtKB:P63018 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 Prp19 complex   ISO UniProtKB:P11142 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 ribonucleoprotein complex   ISO UniProtKB:P11142 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 spliceosomal complex   IEA UniProtKB-KW:KW-0747 2290270 MGI:MGI:1354194 UniProtKB MGI:MGI:1354194 synaptic vesicle   ISO UniProtKB:P63018 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 Molecular Function Term Qualifier Evidence With Reference Notes Source Original Reference(s) ADP binding   ISO UniProtKB:P63018 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 ATP binding   ISO UniProtKB:P63018 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 ATPase activity, coupled   IDA   2290270 MGI:MGI:2652284|PMID:12588994 MGI MGI:MGI:2652284 PMID:12588994 ATPase activity, coupled   ISO UniProtKB:P63018 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 nucleotide binding   IEA UniProtKB-KW:KW-0547 2290270 MGI:MGI:1354194 UniProtKB MGI:MGI:1354194 protein binding   IPI UniProtKB:Q8C845 2290270 MGI:MGI:3798741|PMID:18346207 MGI MGI:MGI:3798741 PMID:18346207 protein binding   IPI UniProtKB:P39689 2290270 MGI:MGI:2652284|PMID:12588994 MGI MGI:MGI:2652284 PMID:12588994 protein binding   IPI UniProtKB:P29752 2290270 MGI:MGI:2681405|PMID:14644449 MGI MGI:MGI:2681405 PMID:14644449 protein binding   IPI UniProtKB:Q06219 2290270 MGI:MGI:3798741|PMID:18346207 MGI MGI:MGI:3798741 PMID:18346207 protein binding   IPI UniProtKB:P25322|UniProtKB:P30285 2290270 MGI:MGI:2652284|PMID:12588994 MGI MGI:MGI:2652284 PMID:12588994 receptor binding   ISO UniProtKB:P63018 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 unfolded protein binding   IPI UniProtKB:P25322|UniProtKB:P30285 2290270 MGI:MGI:2652284|PMID:12588994 MGI MGI:MGI:2652284 PMID:12588994 unfolded protein binding   ISO UniProtKB:P63018 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 Molecular Pathway Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) androgen signaling pathway   ISS RGD:736219 2326084   RGD   antigen processing and presentation pathway   IEA RGD:10733 6907045   KEGG mmu:04612 endocytosis pathway   IEA RGD:10733 6907045   KEGG mmu:04144 Endoplasmic Reticulum-associated degradation pathway   IEA RGD:10733 6907045   KEGG mmu:04141 influenza A virus infection pathway   IEA RGD:10733 6907045   KEGG mmu:05164 measles infection pathway   IEA RGD:10733 6907045   KEGG mmu:05162 mitogen activated protein kinase signaling pathway   IEA RGD:10733 6907045   KEGG mmu:04010 spliceosome pathway   IEA RGD:10733 6907045   KEGG mmu:03040 Toxoplasma gondii infection pathway   IEA RGD:10733 6907045   KEGG mmu:05145 External Database Links KEGG Pathway Antigen processing and presentation Endocytosis Epstein-Barr virus infection Influenza A Legionellosis MAPK signaling pathway Measles Protein processing in endoplasmic reticulum Spliceosome Toxoplasmosis Pathway Interaction Database C-MYB transcription factor network (PID:200153) Regulation of nuclear SMAD2/3 signaling (PID:200003) Disease Annotations Acute Kidney Injury  (ISS) Brain Ischemia  (ISS) Colorectal Neoplasms  (ISS) Diabetic Nephropathies  (ISS) Graft vs Host Disease  (ISS) Huntington Disease  (IEP) Hypertension  (ISS) Hypertension, Renal  (ISS) Inflammatory Bowel Diseases  (IEP) Kidney Reperfusion Injury  (ISS) Macular Degeneration  (ISS) Metabolic Diseases  (ISS) Multiple Sclerosis  (ISS) Multiple Sclerosis, Relapsing-Remitting  (ISS) Myocardial Reperfusion Injury  (IPM) Myocarditis  (IPM) Parkinson Disease  (ISS) Uterine Cervical Neoplasms  (ISS) Gene-Chemical Interaction Annotations (2,4,5-trichlorophenoxy)acetic acid  (EXP) (R)-adrenaline  (ISO) (S)-amphetamine  (EXP) 1-naphthyl isothiocyanate  (ISO) 17alpha-ethynylestradiol  (EXP,ISO) 17beta-estradiol  (ISO) 1H-pyrazole  (EXP) 2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO) 2,4,6-trinitrotoluene  (ISO) 2,4-dinitrotoluene  (ISO) 2-methylcholine  (ISO) 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO) 3,4-methylenedioxymethamphetamine  (EXP) 5-aza-2'-deoxycytidine  (ISO) 5-fluorouracil  (ISO) 7,12-dimethyltetraphene  (EXP) 7H-xanthine  (ISO) 8-bromo-3',5'-cyclic AMP  (ISO) 9H-xanthine  (ISO) acrylamide  (ISO) afimoxifene  (ISO) albendazole  (ISO) all-trans-retinoic acid  (ISO) ammonium chloride  (ISO) apigenin  (EXP) Aroclor 1254  (ISO) arsenic atom  (EXP) arsenite(3-)  (ISO) astemizole  (ISO) bathocuproine disulfonic acid  (ISO) benzene  (ISO) benzo[a]pyrene  (EXP,ISO) bifenthrin  (ISO) bis(2-ethylhexyl) phthalate  (EXP,ISO) bisphenol A  (ISO) bromobenzene  (ISO) C60 fullerene  (ISO) cadmium dichloride  (EXP) cadmium sulfate  (ISO) chloroprene  (EXP) chlorpyrifos  (EXP) choline  (EXP) ciguatoxin CTX1B  (EXP) cisplatin  (ISO) cobalt dichloride  (ISO) copper atom  (ISO) copper(0)  (ISO) copper(2+) sulfate  (EXP,ISO) cyclophosphamide  (ISO) cyclosporin A  (ISO) dasatinib (anhydrous)  (ISO) Delta(9)-tetrahydrocannabinol  (EXP,ISO) dexamethasone  (EXP) diarsenic trioxide  (ISO) diazoxide  (EXP) dibutyl phthalate  (EXP) diethyl maleate  (EXP) dimethylarsinic acid  (EXP) disodium selenite  (ISO) diuron  (ISO) doxorubicin  (ISO) fenofibrate  (EXP) ferric oxide  (EXP) folic acid  (EXP) formetanate  (ISO) fulvestrant  (ISO) furan  (EXP,ISO) gamma-poly(L-glutamic acid) macromolecule  (ISO) hyaluronic acid  (ISO) hydralazine  (ISO) hydrogen peroxide  (ISO) hydroxyurea  (ISO) ibuprofen  (ISO) imipramine  (ISO) indomethacin  (EXP,ISO) ionomycin  (ISO) iron atom  (ISO) isoprenaline  (EXP) ivermectin  (ISO) L-methionine  (EXP) lead diacetate  (EXP) lovastatin  (EXP) maneb  (EXP) manganese atom  (ISO) manganese(0)  (ISO) methamphetamine  (ISO) methomyl  (ISO) methotrexate  (EXP) microcystin-LR  (EXP) mitomycin C  (ISO) monocrotaline  (EXP) morphine  (ISO) N-methylformamide  (EXP) nickel atom  (ISO) nickel dichloride  (ISO) nitrofurantoin  (ISO) ozone  (EXP) paracetamol  (EXP,ISO) paraquat  (EXP) perfluorooctane-1-sulfonic acid  (ISO) perfluorooctanoic acid  (ISO) phenobarbital  (EXP,ISO) phenytoin  (EXP) phlorizin  (EXP) phorbol 13-acetate 12-myristate  (ISO) phorone  (ISO) pirimicarb  (ISO) pirinixic acid  (EXP,ISO) pregnenolone 16alpha-carbonitrile  (ISO) propiconazole  (EXP) prostaglandin A1  (EXP) pyrogallol  (EXP) quinolin-8-ol  (ISO) raloxifene  (ISO) rifampicin  (EXP) S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP,ISO) sertraline  (ISO) sevoflurane  (ISO) silicon dioxide  (EXP) simvastatin  (ISO) tacrolimus hydrate  (ISO) tamoxifen  (EXP) trichloroethene  (ISO) troglitazone  (EXP) tungsten atom  (ISO) valproic acid  (ISO) zinc pyrithione  (ISO) zinc sulfate  (ISO) Gene Ontology Annotations Biological Process ATP catabolic process  (IDA) chaperone mediated protein folding requiring cofactor  (IGI,ISO) chaperone-mediated protein folding  (ISO) mRNA processing  (IEA) negative regulation of transcription, DNA-dependent  (ISO) protein folding  (IDA) regulation of cell cycle  (IDA) regulation of transcription, DNA-dependent  (IEA) response to stress  (IEA) RNA splicing  (IEA) transcription, DNA-dependent  (IEA) Cellular Component cell surface  (ISO) cytoplasm  (ISO) cytosol  (IDA) extracellular vesicular exosome  (IDA,ISO) intracellular  (IDA) neuron projection  (ISO) neuronal cell body  (ISO) nucleolus  (ISO) nucleus  (ISO) protein complex  (ISO) Prp19 complex  (ISO) ribonucleoprotein complex  (ISO) spliceosomal complex  (IEA) synaptic vesicle  (ISO) Molecular Function ADP binding  (ISO) ATP binding  (ISO) ATPase activity, coupled  (IDA,ISO) nucleotide binding  (IEA) protein binding  (IPI) receptor binding  (ISO) unfolded protein binding  (IPI,ISO) Molecular Pathway Annotations androgen signaling pathway  (ISS) antigen processing and presentation pathway  (IEA) endocytosis pathway  (IEA) Endoplasmic Reticulum-associated degradation pathway  (IEA) influenza A virus infection pathway  (IEA) measles infection pathway  (IEA) mitogen activated protein kinase signaling pathway  (IEA) spliceosome pathway  (IEA) Toxoplasma gondii infection pathway  (IEA) External Database Links KEGG Pathway Antigen processing and presentation Endocytosis Epstein-Barr virus infection Influenza A Legionellosis MAPK signaling pathway Measles Protein processing in endoplasmic reticulum Spliceosome Toxoplasmosis Pathway Interaction Database C-MYB transcription factor network (PID:200153) Regulation of nuclear SMAD2/3 signaling (PID:200003) References - curated 1. Alvarez-Erviti L, etal., Arch Neurol. 2010 Dec;67(12):1464-72. Epub 2010 Aug 9. 2. Calabrese V, etal., J Neurochem. 2007 May;101(3):709-17. Epub 2007 Jan 4. 3. Chiba S, etal., J Neurol Sci. 2006 Feb 15;241(1-2):39-43. Epub 2005 Nov 21. 4. Goral J, etal., Clin Immunol Immunopathol. 1998 Mar;86(3):252-8. 5. Kawai J, etal., Nature 2001 Feb 8;409(6821):685-90. 6. Ko MS, etal., Hum Mol Genet 1998 Nov;7(12):1967-78. 7. Kocsis J, etal., Cell Stress Chaperones. 2010 Mar;15(2):143-51. Epub 2009 Jul 4. 8. Koga H, etal., J Neurosci. 2011 Dec 14;31(50):18492-505. 9. Komatsuda A, etal., Pathol Int. 1999 Jun;49(6):513-8. 10. Lederman M, etal., Invest Ophthalmol Vis Sci. 2010 Jan;51(1):53-8. Epub 2009 Aug 13. 11. Lo Bianco C, etal., J Clin Invest. 2008 Sep;118(9):3087-97. 12. Lomnytska MI, etal., Proteomics Clin Appl. 2010 Jan;4(1):17-31. doi: 10.1002/prca.200900086. Epub 2009 Nov 11. 13. Mashukova A, etal., Mol Cell Biol. 2011 Feb;31(4):756-65. Epub 2010 Dec 6. 14. MGD and Homologene mouse data transfer 15. MGD data from the GO Consortium 16. Miyazaki T, etal., J Biol Chem. 2004 Apr 23;279(17):17295-300. Epub 2004 Feb 13. 17. Morita K, etal., Ren Fail. 1995 Jul;17(4):405-19. 18. Oguri M, etal., Mol Med Rep. 2009 Mar-Apr;2(2):205-11. doi: 10.3892/mmr_00000085. 19. Okazaki Y, etal., Nature 2002 Dec 5;420(6915):563-73. 20. Pennisi G, etal., Biochem Pharmacol. 2011 Nov 15;82(10):1490-9. Epub 2011 Jul 30. 21. Pipeline to import KEGG annotations from KEGG into RGD Pathway Ontology 22. Prescott J and Coetzee GA, Cancer Lett. 2006 Jan 8;231(1):12-9. 23. RGD automated import pipeline for gene-chemical interactions 24. Tessari P, etal., J Proteome Res. 2007 Mar;6(3):976-86. 25. Timofeeva AV, etal., Ann N Y Acad Sci. 2006 Dec;1091:319-35. 26. Zhang F, etal., J Neurochem. 2006 Jul;98(1):102-12. 27. Zou N, etal., Am J Physiol Heart Circ Physiol. 2008 Jun;294(6):H2805-13. Epub 2008 Apr 25. References - uncurated PubMed 10095055   10349636   10464095   10545106   10631312   10862698   10922068   10942430   11032181   11042159   11076861   11461004   12114509   12477932   12482845   12495215   12588994   12617806   12748967   1282084   1375913   14610273   14644449   15129916   15215307   15292236   15350538   15456869   15489334   15639784   15745951   15782199   15802271   15952741   16113801   16141072   16141073   16196101   16602821   16604525   16690984   16906134   16944949   16973439   17296600   17954934   18095342   18346207   18379898   18463355   18799693   18841484   19055850   19136429   19171884   19448144   19551494   19724054   19737422   19841136   20003465   20018937   20095651   2010034   20111006   20564261   20884878   21151134   21183741   21209184   21278135   21565611   21677750   21832061   2251119   23235156   2429302   2832726   3334718   3628016   7813466   7988674   8631027   8682318   9066258   9122205   9305631   9431456   9675148   9712876   9880236 RGD Disease Portals Hspa8 has been annotated in the following RGD Disease Portals. Biological Process Cancer Diseases Cancer Pathways Cardiovascular Diseases Cardiovascular Pathways Diabetes Diseases Diabetes Pathways Immune and Inflammatory Diseases Immune and Inflammatory Pathways Neurological Diseases Neurological Pathways Obesity Diseases Obesity Pathways Respiratory Pathways Genomics Comparative Map Data Hspa8   (Mus musculus) Map Chr Position Strand Source Mouse Genome Assembly GRCm38 9 40,801,273 - 40,805,199 + NCBI Mouse cM Map 9 21.55   NCBI Mouse Celera Assembly 9 38,034,609 - 38,038,251 + NCBI Mouse Genome Assembly Build 37 9 40,609,356 - 40,613,282 + NCBI Mouse Genome Assembly Build 36.1 9 40,609,356 - 40,613,282 + NCBI Mouse Cytogenetic Map 9 A5.1   NCBI HSPA8   (Homo sapiens) Map Chr Position Strand Source Human Alternate Assembly CHM1_1 11 122,793,965 - 122,798,666 - NCBI Human Genome Assembly HuRef 11 118,870,278 - 118,874,980 - NCBI Human Genome Assembly GRCh37 11 122,928,200 - 122,932,901 - NCBI Human Genome Assembly Build 36 11 122,433,410 - 122,438,054 - NCBI Human Cytogenetic Map 11 q24.1   NCBI Human Genome Assembly 11 122,433,410 - 122,438,054   NCBI Hspa8   (Rattus norvegicus) Map Chr Position Strand Source Rat Cytogenetic Map 8 q22   NCBI RGSC Genome Assembly v5.0 8 46,005,304 - 46,006,864 - NCBI RGSC Genome Assembly v5.0 8 43,478,238 - 43,480,456 + NCBI RGSC Genome Assembly v3.4 8 43,784,035 - 43,787,760 + NCBI Rat Celera Assembly 8 40,782,916 - 40,786,778 + NCBI Genome Assembly 3.1 8 43,792,829 - 43,796,525 + NCBI Position Markers RH125443   Map Chr Position Strand Source Mouse Cytogenetic Map 9 A5.1   UniSTS PMC113864P1   Map Chr Position Strand Source Mouse Genome Assembly GRCm38 9 40,803,581 - 40,804,081   UniSTS Mouse Genome Assembly GRCm38 9 40,803,581 - 40,803,669   UniSTS Mouse Celera Assembly 9 38,036,628 - 38,037,128   UniSTS Mouse Celera Assembly 9 38,036,628 - 38,036,716   UniSTS Mouse Genome Assembly Build 37 9 40,611,664 - 40,612,164   UniSTS Mouse Genome Assembly Build 37 9 40,611,664 - 40,611,752   UniSTS Mouse Cytogenetic Map 9 A5.1   UniSTS Hspa8   Map Chr Position Strand Source Mouse cM Map 9 24.0   UniSTS Mouse Cytogenetic Map 9 A5.1   UniSTS QTLs in Region (Mouse Genome Assembly Build 37) The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer RGD ID Symbol Name LOD P Value Trait Sub Trait Chr Start Stop Species 1300532 Tbs2_m tuberculosis severity 2 (mouse) Not determined 9 12266259 46266403 Mouse 1301246 Hpic5_m haloperidol-induced catelepsy 5 (mouse) Not determined 9 14167847 48167980 Mouse 4141591 Cq4_m cholesterol QTL 4 (mouse) Not determined 9 15308040 49308179 Mouse 1357637 Si5lq2_m serum IGFBP-5 level QTL 2 (mouse) Not determined 9 15308040 49308179 Mouse 1300777 Chol10_m cholesterol 10 (mouse) Not determined 9 15308040 49308179 Mouse 1301421 Lgth4_m body length 4 (mouse) Not determined 9 15308040 49308179 Mouse 4141447 Cfmq2_m cystic fibrosis modifier QTL 2 (mouse) Not determined 9 15308040 49308179 Mouse 1357465 Vtbt6_m vertebral trabecular bone trait 6 (mouse) Not determined 9 16875129 50875232 Mouse 1300643 Pvcan2_m protection against vaginal candidiasis 2 (mouse) Not determined 9 19839695 53839814 Mouse 1301007 Pid2_m prion incubation determinant 2 (mouse) Not determined 9 20049651 54049781 Mouse 1301439 Morph2_m morphine antinociception 2 (mouse) Not determined 9 20049651 54049781 Mouse 1301045 Sluc10_m susceptibility to lung cancer 10 (mouse) Not determined 9 20202486 54202659 Mouse 1302015 C10bw2_m castaneus 10 week body weight 2 (mouse) Not determined 9 20202486 54202659 Mouse 4141507 Brml5_m bone response to mechanical loading 5 (mouse) Not determined 9 20202486 54202659 Mouse 1301883 Skull12_m skull morphology 12 (mouse) Not determined 9 20202486 54202659 Mouse 4142352 Lmr17_m leishmaniasis resistance 17 (mouse) Not determined 9 20202486 54202659 Mouse 1301631 Orgwq7_m organ weight QTL 7 (mouse) Not determined 9 20202486 54202659 Mouse 1357900 Alaa2_m alopecia areata 2 (mouse) Not determined 9 23315883 57315980 Mouse 4141166 Appd1_m APP associated premature death 1 (mouse) Not determined 9 23462577 57462701 Mouse 1301501 Lmr2_m leishmaniasis resistance 2 (mouse) Not determined 9 24362343 58362480 Mouse 1301334 Cocia10_m cocaine induced activation 10 (mouse) Not determined 9 24695932 58696113 Mouse 1301000 Obq5_m obesity QTL 5 (mouse) Not determined 9 24695932 58696113 Mouse 1300932 Hdlq17_m HDL QTL 17 (mouse) Not determined 9 26693207 60693338 Mouse 1558993 Tdmq1_m type 2 diabetes modifying QTL 1 (mouse) Not determined 9 29041438 63041650 Mouse 1301365 Ap5q_m alcohol preference 5 QTL (mouse) Not determined 9 29949949 63950062 Mouse 4141260 Actre6_m activity response to ethanol 6 (mouse) Not determined 9 30439809 64439925 Mouse 1357746 Vtbt7_m vertebral trabecular bone trait 7 (mouse) Not determined 9 30636700 64636806 Mouse 4140969 Chcmq2_m mean cell hemoglobin concentration QTL 2 (mouse) Not determined 9 32313165 66313512 Mouse 1357768 Baa1_m BALB/c autoimmunity 1 (mouse) Not determined 9 32317103 66317316 Mouse 1302180 Actd4_m activity-distance traveled 4 (mouse) Not determined 9 32331368 66331662 Mouse 4141148 Cq5_m cholesterol QTL 5 (mouse) Not determined 9 32349226 66349351 Mouse 1301782 Chol11_m cholesterol 11 (mouse) Not determined 9 32349226 66349351 Mouse 1301692 Hts_m hypothermia sensitivity (mouse) Not determined 9 32407977 66408226 Mouse 4141323 Ptnu3_m proteinuria 3 (mouse) Not determined 9 32786507 66786641 Mouse 1357709 Si5lq3_m serum IGFBP-5 level QTL 3 (mouse) Not determined 9 33007830 67007945 Mouse 1301651 Tlf2_m T lymphocyte fraction 2 (mouse) Not determined 9 33007830 67007945 Mouse 4141078 Alpq1_m alcohol preference QTL 1 (mouse) Not determined 9 34931283 68931404 Mouse 1301972 Cocrb8_m cocaine related behavior 8 (mouse) Not determined 9 34931283 68931404 Mouse 1558968 Tbdr1_m body temperature response to dietary restriction, QTL 1 (mouse) Not determined 9 34931283 68931404 Mouse 1301252 Etohc3_m ethanol consumption 3 (mouse) Not determined 9 34931283 68931404 Mouse 4142042 Alpq3_m alcohol preference QTL 3 (mouse) Not determined 9 37202486 98720073 Mouse Sequence Nucleotide Sequences Nucleotide RefSeqs NM_031165 (Get FASTA) Search GEO for Microarray Profiles GenBank Nucleotide AAHY01077372 (Get FASTA) Search GEO for Microarray Profiles   AAHY01077373 (Get FASTA) Search GEO for Microarray Profiles   AC158355 (Get FASTA) Search GEO for Microarray Profiles   AK004608 (Get FASTA) Search GEO for Microarray Profiles   AK035286 (Get FASTA) Search GEO for Microarray Profiles   AK075935 (Get FASTA) Search GEO for Microarray Profiles   AK081701 (Get FASTA) Search GEO for Microarray Profiles   AK098074 (Get FASTA) Search GEO for Microarray Profiles   AK135281 (Get FASTA) Search GEO for Microarray Profiles   AK145416 (Get FASTA) Search GEO for Microarray Profiles   AK145579 (Get FASTA) Search GEO for Microarray Profiles   AK146547 (Get FASTA) Search GEO for Microarray Profiles   AK146708 (Get FASTA) Search GEO for Microarray Profiles   AK146985 (Get FASTA) Search GEO for Microarray Profiles   AK147864 (Get FASTA) Search GEO for Microarray Profiles   AK149954 (Get FASTA) Search GEO for Microarray Profiles   AK150474 (Get FASTA) Search GEO for Microarray Profiles   AK150498 (Get FASTA) Search GEO for Microarray Profiles   AK150701 (Get FASTA) Search GEO for Microarray Profiles   AK150846 (Get FASTA) Search GEO for Microarray Profiles   AK150958 (Get FASTA) Search GEO for Microarray Profiles   AK151041 (Get FASTA) Search GEO for Microarray Profiles   AK151065 (Get FASTA) Search GEO for Microarray Profiles   AK151127 (Get FASTA) Search GEO for Microarray Profiles   AK151287 (Get FASTA) Search GEO for Microarray Profiles   AK151435 (Get FASTA) Search GEO for Microarray Profiles   AK151516 (Get FASTA) Search GEO for Microarray Profiles   AK151537 (Get FASTA) Search GEO for Microarray Profiles   AK151741 (Get FASTA) Search GEO for Microarray Profiles   AK151775 (Get FASTA) Search GEO for Microarray Profiles   AK151808 (Get FASTA) Search GEO for Microarray Profiles   AK151865 (Get FASTA) Search GEO for Microarray Profiles   AK151892 (Get FASTA) Search GEO for Microarray Profiles   AK151948 (Get FASTA) Search GEO for Microarray Profiles   AK151997 (Get FASTA) Search GEO for Microarray Profiles   AK152315 (Get FASTA) Search GEO for Microarray Profiles   AK152598 (Get FASTA) Search GEO for Microarray Profiles   AK152697 (Get FASTA) Search GEO for Microarray Profiles   AK152703 (Get FASTA) Search GEO for Microarray Profiles   AK152768 (Get FASTA) Search GEO for Microarray Profiles   AK152803 (Get FASTA) Search GEO for Microarray Profiles   AK153032 (Get FASTA) Search GEO for Microarray Profiles   AK153834 (Get FASTA) Search GEO for Microarray Profiles   AK157831 (Get FASTA) Search GEO for Microarray Profiles   AK159479 (Get FASTA) Search GEO for Microarray Profiles   AK162775 (Get FASTA) Search GEO for Microarray Profiles   AK163987 (Get FASTA) Search GEO for Microarray Profiles   AK164000 (Get FASTA) Search GEO for Microarray Profiles   AK166545 (Get FASTA) Search GEO for Microarray Profiles   AK166643 (Get FASTA) Search GEO for Microarray Profiles   AK166721 (Get FASTA) Search GEO for Microarray Profiles   AK166767 (Get FASTA) Search GEO for Microarray Profiles   AK166776 (Get FASTA) Search GEO for Microarray Profiles   AK166808 (Get FASTA) Search GEO for Microarray Profiles   AK166830 (Get FASTA) Search GEO for Microarray Profiles   AK166846 (Get FASTA) Search GEO for Microarray Profiles   AK166861 (Get FASTA) Search GEO for Microarray Profiles   AK166873 (Get FASTA) Search GEO for Microarray Profiles   AK166908 (Get FASTA) Search GEO for Microarray Profiles   AK166910 (Get FASTA) Search GEO for Microarray Profiles   AK166913 (Get FASTA) Search GEO for Microarray Profiles   AK166933 (Get FASTA) Search GEO for Microarray Profiles   AK167043 (Get FASTA) Search GEO for Microarray Profiles   AK167121 (Get FASTA) Search GEO for Microarray Profiles   AK167122 (Get FASTA) Search GEO for Microarray Profiles   AK167134 (Get FASTA) Search GEO for Microarray Profiles   AK167163 (Get FASTA) Search GEO for Microarray Profiles   AK167218 (Get FASTA) Search GEO for Microarray Profiles   AK167229 (Get FASTA) Search GEO for Microarray Profiles   AK167254 (Get FASTA) Search GEO for Microarray Profiles   AK167414 (Get FASTA) Search GEO for Microarray Profiles   AK167845 (Get FASTA) Search GEO for Microarray Profiles   AK167910 (Get FASTA) Search GEO for Microarray Profiles   AK168435 (Get FASTA) Search GEO for Microarray Profiles   AK168492 (Get FASTA) Search GEO for Microarray Profiles   AK168511 (Get FASTA) Search GEO for Microarray Profiles   AK168519 (Get FASTA) Search GEO for Microarray Profiles   AK168542 (Get FASTA) Search GEO for Microarray Profiles   AK168577 (Get FASTA) Search GEO for Microarray Profiles   AK168625 (Get FASTA) Search GEO for Microarray Profiles   AK168654 (Get FASTA) Search GEO for Microarray Profiles   AK168711 (Get FASTA) Search GEO for Microarray Profiles   AK168750 (Get FASTA) Search GEO for Microarray Profiles   AK168776 (Get FASTA) Search GEO for Microarray Profiles   AK168887 (Get FASTA) Search GEO for Microarray Profiles   AK168934 (Get FASTA) Search GEO for Microarray Profiles   AK169093 (Get FASTA) Search GEO for Microarray Profiles   AK169179 (Get FASTA) Search GEO for Microarray Profiles   AK169236 (Get FASTA) Search GEO for Microarray Profiles   AK169293 (Get FASTA) Search GEO for Microarray Profiles   AK169329 (Get FASTA) Search GEO for Microarray Profiles   AK169594 (Get FASTA) Search GEO for Microarray Profiles   AK171434 (Get FASTA) Search GEO for Microarray Profiles   AK177099 (Get FASTA) Search GEO for Microarray Profiles   AK178143 (Get FASTA) Search GEO for Microarray Profiles   AK178681 (Get FASTA) Search GEO for Microarray Profiles   AK180175 (Get FASTA) Search GEO for Microarray Profiles   AK180949 (Get FASTA) Search GEO for Microarray Profiles   AK184860 (Get FASTA) Search GEO for Microarray Profiles   AK185576 (Get FASTA) Search GEO for Microarray Profiles   AK186515 (Get FASTA) Search GEO for Microarray Profiles   AK188190 (Get FASTA) Search GEO for Microarray Profiles   AK188441 (Get FASTA) Search GEO for Microarray Profiles   AK190071 (Get FASTA) Search GEO for Microarray Profiles   AK190509 (Get FASTA) Search GEO for Microarray Profiles   AK190603 (Get FASTA) Search GEO for Microarray Profiles   AK190650 (Get FASTA) Search GEO for Microarray Profiles   AK190709 (Get FASTA) Search GEO for Microarray Profiles   AK190962 (Get FASTA) Search GEO for Microarray Profiles   AK191135 (Get FASTA) Search GEO for Microarray Profiles   AK191872 (Get FASTA) Search GEO for Microarray Profiles   AK192102 (Get FASTA) Search GEO for Microarray Profiles   AK192182 (Get FASTA) Search GEO for Microarray Profiles   AK192272 (Get FASTA) Search GEO for Microarray Profiles   AK192391 (Get FASTA) Search GEO for Microarray Profiles   AK192614 (Get FASTA) Search GEO for Microarray Profiles   AK192871 (Get FASTA) Search GEO for Microarray Profiles   AK193113 (Get FASTA) Search GEO for Microarray Profiles   AK193674 (Get FASTA) Search GEO for Microarray Profiles   AK193850 (Get FASTA) Search GEO for Microarray Profiles   AK194175 (Get FASTA) Search GEO for Microarray Profiles   AK194470 (Get FASTA) Search GEO for Microarray Profiles   AK194530 (Get FASTA) Search GEO for Microarray Profiles   AK195094 (Get FASTA) Search GEO for Microarray Profiles   AK195240 (Get FASTA) Search GEO for Microarray Profiles   AK195783 (Get FASTA) Search GEO for Microarray Profiles   AK196257 (Get FASTA) Search GEO for Microarray Profiles   AK196405 (Get FASTA) Search GEO for Microarray Profiles   AK196709 (Get FASTA) Search GEO for Microarray Profiles   AK196874 (Get FASTA) Search GEO for Microarray Profiles   AK197043 (Get FASTA) Search GEO for Microarray Profiles   AK197127 (Get FASTA) Search GEO for Microarray Profiles   AK197132 (Get FASTA) Search GEO for Microarray Profiles   AK197383 (Get FASTA) Search GEO for Microarray Profiles   AK197524 (Get FASTA) Search GEO for Microarray Profiles   AK197541 (Get FASTA) Search GEO for Microarray Profiles   AK197732 (Get FASTA) Search GEO for Microarray Profiles   AK197810 (Get FASTA) Search GEO for Microarray Profiles   AK197877 (Get FASTA) Search GEO for Microarray Profiles   AK197951 (Get FASTA) Search GEO for Microarray Profiles   AK197978 (Get FASTA) Search GEO for Microarray Profiles   AK198438 (Get FASTA) Search GEO for Microarray Profiles   AK198838 (Get FASTA) Search GEO for Microarray Profiles   AK199036 (Get FASTA) Search GEO for Microarray Profiles   AK199049 (Get FASTA) Search GEO for Microarray Profiles   AK199142 (Get FASTA) Search GEO for Microarray Profiles   AK199143 (Get FASTA) Search GEO for Microarray Profiles   AK199178 (Get FASTA) Search GEO for Microarray Profiles   AK199284 (Get FASTA) Search GEO for Microarray Profiles   AK199354 (Get FASTA) Search GEO for Microarray Profiles   AK199410 (Get FASTA) Search GEO for Microarray Profiles   AK199504 (Get FASTA) Search GEO for Microarray Profiles   AK200094 (Get FASTA) Search GEO for Microarray Profiles   AK200192 (Get FASTA) Search GEO for Microarray Profiles   AK200291 (Get FASTA) Search GEO for Microarray Profiles   AK200309 (Get FASTA) Search GEO for Microarray Profiles   AK201032 (Get FASTA) Search GEO for Microarray Profiles   AK201037 (Get FASTA) Search GEO for Microarray Profiles   AK201241 (Get FASTA) Search GEO for Microarray Profiles   AK201767 (Get FASTA) Search GEO for Microarray Profiles   AK202337 (Get FASTA) Search GEO for Microarray Profiles   AK202357 (Get FASTA) Search GEO for Microarray Profiles   AK202523 (Get FASTA) Search GEO for Microarray Profiles   AK202859 (Get FASTA) Search GEO for Microarray Profiles   AK203911 (Get FASTA) Search GEO for Microarray Profiles   AK204189 (Get FASTA) Search GEO for Microarray Profiles   AK204272 (Get FASTA) Search GEO for Microarray Profiles   AK204416 (Get FASTA) Search GEO for Microarray Profiles   AK204472 (Get FASTA) Search GEO for Microarray Profiles   AK204890 (Get FASTA) Search GEO for Microarray Profiles   AK204952 (Get FASTA) Search GEO for Microarray Profiles   AK205012 (Get FASTA) Search GEO for Microarray Profiles   AK205187 (Get FASTA) Search GEO for Microarray Profiles   AK205346 (Get FASTA) Search GEO for Microarray Profiles   AK206134 (Get FASTA) Search GEO for Microarray Profiles   AK206185 (Get FASTA) Search GEO for Microarray Profiles   AK206309 (Get FASTA) Search GEO for Microarray Profiles   AK206953 (Get FASTA) Search GEO for Microarray Profiles   AK207066 (Get FASTA) Search GEO for Microarray Profiles   AK207762 (Get FASTA) Search GEO for Microarray Profiles   AK208306 (Get FASTA) Search GEO for Microarray Profiles   AK208890 (Get FASTA) Search GEO for Microarray Profiles   AK208972 (Get FASTA) Search GEO for Microarray Profiles   AK209289 (Get FASTA) Search GEO for Microarray Profiles   AK209652 (Get FASTA) Search GEO for Microarray Profiles   AK210012 (Get FASTA) Search GEO for Microarray Profiles   AK210051 (Get FASTA) Search GEO for Microarray Profiles   AK210805 (Get FASTA) Search GEO for Microarray Profiles   AK210977 (Get FASTA) Search GEO for Microarray Profiles   AK211519 (Get FASTA) Search GEO for Microarray Profiles   AK212081 (Get FASTA) Search GEO for Microarray Profiles   AK212540 (Get FASTA) Search GEO for Microarray Profiles   AK212778 (Get FASTA) Search GEO for Microarray Profiles   AK212914 (Get FASTA) Search GEO for Microarray Profiles   AK212927 (Get FASTA) Search GEO for Microarray Profiles   AK213816 (Get FASTA) Search GEO for Microarray Profiles   AK214003 (Get FASTA) Search GEO for Microarray Profiles   AK214010 (Get FASTA) Search GEO for Microarray Profiles   AK214442 (Get FASTA) Search GEO for Microarray Profiles   AK215080 (Get FASTA) Search GEO for Microarray Profiles   AK215414 (Get FASTA) Search GEO for Microarray Profiles   AK215442 (Get FASTA) Search GEO for Microarray Profiles   AK216159 (Get FASTA) Search GEO for Microarray Profiles   AK216732 (Get FASTA) Search GEO for Microarray Profiles   AK216875 (Get FASTA) Search GEO for Microarray Profiles   AK216907 (Get FASTA) Search GEO for Microarray Profiles   AK216947 (Get FASTA) Search GEO for Microarray Profiles   AK217000 (Get FASTA) Search GEO for Microarray Profiles   AK217051 (Get FASTA) Search GEO for Microarray Profiles   AK217350 (Get FASTA) Search GEO for Microarray Profiles   AK217841 (Get FASTA) Search GEO for Microarray Profiles   AK217906 (Get FASTA) Search GEO for Microarray Profiles   AK217914 (Get FASTA) Search GEO for Microarray Profiles   AK217969 (Get FASTA) Search GEO for Microarray Profiles   AK218563 (Get FASTA) Search GEO for Microarray Profiles   AK218570 (Get FASTA) Search GEO for Microarray Profiles   AK218761 (Get FASTA) Search GEO for Microarray Profiles   AK218886 (Get FASTA) Search GEO for Microarray Profiles   AK218914 (Get FASTA) Search GEO for Microarray Profiles   AK219217 (Get FASTA) Search GEO for Microarray Profiles   AK219219 (Get FASTA) Search GEO for Microarray Profiles   AK219581 (Get FASTA) Search GEO for Microarray Profiles   AK220016 (Get FASTA) Search GEO for Microarray Profiles   BC006722 (Get FASTA) Search GEO for Microarray Profiles   BC066191 (Get FASTA) Search GEO for Microarray Profiles   BC085486 (Get FASTA) Search GEO for Microarray Profiles   BC089322 (Get FASTA) Search GEO for Microarray Profiles   BC089457 (Get FASTA) Search GEO for Microarray Profiles   BC094900 (Get FASTA) Search GEO for Microarray Profiles   BC106169 (Get FASTA) Search GEO for Microarray Profiles   BC106193 (Get FASTA) Search GEO for Microarray Profiles   CH466522 (Get FASTA) Search GEO for Microarray Profiles   M13967 (Get FASTA) Search GEO for Microarray Profiles   M19141 (Get FASTA) Search GEO for Microarray Profiles   U27129 (Get FASTA) Search GEO for Microarray Profiles   U73744 (Get FASTA) Search GEO for Microarray Profiles   X05837 (Get FASTA) Search GEO for Microarray Profiles   X05838 (Get FASTA) Search GEO for Microarray Profiles   X54401 (Get FASTA) Search GEO for Microarray Profiles   X54402 (Get FASTA) Search GEO for Microarray Profiles   X54403 (Get FASTA) Search GEO for Microarray Profiles Reference Sequences RefSeq Acc Id: NM_031165 RefSeq Status: PROVISIONAL Type: CODING Protein Acc Id: NP_112442 Position: Map Chr Position Strand Source Mouse Genome Assembly GRCm38 9 40,801,273 - 40,805,199 + ENTREZGENE Mouse cM Map 9   + ENTREZGENE Mouse Celera Assembly 9 38,034,609 - 38,038,251 + RGD Mouse Genome Assembly Build 37 9 40,609,356 - 40,613,282 + RGD RefSeq Acc Id: NR_015570 RefSeq Status: Type: NON-CODING Position: Map Chr Position Strand Source Mouse Genome Assembly Build 37 9 40,612,686 - 40,613,283 + RGD Protein Sequences Protein RefSeqs NP_112442 (Get FASTA) GenBank Protein AAA37869 (Get FASTA)   AAB18391 (Get FASTA)   AAC52836 (Get FASTA)   AAH06722 (Get FASTA)   AAH66191 (Get FASTA)   AAH85486 (Get FASTA)   AAH89322 (Get FASTA)   AAH89457 (Get FASTA)   AAH94900 (Get FASTA)   AAI06170 (Get FASTA)   AAI06194 (Get FASTA)   BAC29016 (Get FASTA)   BAC36065 (Get FASTA)   BAE22472 (Get FASTA)   BAE26427 (Get FASTA)   BAE26523 (Get FASTA)   BAE27374 (Get FASTA)   BAE27588 (Get FASTA)   BAE28187 (Get FASTA)   BAE29191 (Get FASTA)   BAE29591 (Get FASTA)   BAE29612 (Get FASTA)   BAE29780 (Get FASTA)   BAE29904 (Get FASTA)   BAE29990 (Get FASTA)   BAE30058 (Get FASTA)   BAE30081 (Get FASTA)   BAE30135 (Get FASTA)   BAE30272 (Get FASTA)   BAE30398 (Get FASTA)   BAE30465 (Get FASTA)   BAE30484 (Get FASTA)   BAE30654 (Get FASTA)   BAE30681 (Get FASTA)   BAE30707 (Get FASTA)   BAE30753 (Get FASTA)   BAE30776 (Get FASTA)   BAE30822 (Get FASTA)   BAE30861 (Get FASTA)   BAE31346 (Get FASTA)   BAE31427 (Get FASTA)   BAE31432 (Get FASTA)   BAE31508 (Get FASTA)   BAE31664 (Get FASTA)   BAE32204 (Get FASTA)   BAE34215 (Get FASTA)   BAE35116 (Get FASTA)   BAE37056 (Get FASTA)   BAE37572 (Get FASTA)   BAE37581 (Get FASTA)   BAE38912 (Get FASTA)   BAE38970 (Get FASTA)   BAE39005 (Get FASTA)   BAE39012 (Get FASTA)   BAE39036 (Get FASTA)   BAE39053 (Get FASTA)   BAE39065 (Get FASTA)   BAE39076 (Get FASTA)   BAE39084 (Get FASTA)   BAE39109 (Get FASTA)   BAE39111 (Get FASTA)   BAE39113 (Get FASTA)   BAE39127 (Get FASTA)   BAE39211 (Get FASTA)   BAE39269 (Get FASTA)   BAE39270 (Get FASTA)   BAE39280 (Get FASTA)   BAE39304 (Get FASTA)   BAE39344 (Get FASTA)   BAE39353 (Get FASTA)   BAE39865 (Get FASTA)   BAE39917 (Get FASTA)   BAE40342 (Get FASTA)   BAE40379 (Get FASTA)   BAE40394 (Get FASTA)   BAE40398 (Get FASTA)   BAE40419 (Get FASTA)   BAE40553 (Get FASTA)   BAE40590 (Get FASTA)   BAE40612 (Get FASTA)   BAE40704 (Get FASTA)   BAE40745 (Get FASTA)   BAE40876 (Get FASTA)   BAE40957 (Get FASTA)   BAE41004 (Get FASTA)   BAE41049 (Get FASTA)   BAE41082 (Get FASTA)   BAE41246 (Get FASTA)   BAE42451 (Get FASTA)   CAA38267 (Get FASTA)   CAA38268 (Get FASTA)   CAA38269 (Get FASTA)   CAB57815 (Get FASTA)   EDL25525 (Get FASTA)   P63017 (Get FASTA) Promoters RGD ID: 6848417 Promoter ID: MM_ACW:50213 Type: CpG-Island SO ACC ID: SO:0000170 Source: MPROMDB Tissues & Cell Lines: 3T3L1_Day6 Transcripts: HSPA8.LSEP07 Position: Map Chr Position Strand Source Mouse Genome Assembly Build 36.1 9 40,607,641 - 40,608,141 + MPROMDB RGD ID: 6844666 Promoter ID: MM_KWN:57009 Type: CpG-Island SO ACC ID: SO:0000170 Source: MPROMDB Tissues & Cell Lines: 3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen Transcripts: ENSMUST00000117870,   OTTMUST00000074856,   OTTMUST00000074859,   OTTMUST00000074860,   OTTMUST00000074861,   OTTMUST00000074862,   OTTMUST00000074863,   UC009OZY.1,   UC009OZZ.1 Position: Map Chr Position Strand Source Mouse Genome Assembly Build 36.1 9 40,608,076 - 40,610,482 + MPROMDB RGD ID: 6883116 Promoter ID: EPDNEW_M5009 Type: preliminary Name: Hspa8_1 Description: heat shock protein 8 SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) Position: Map Chr Position Strand Source Mouse Genome Assembly Build 36.1 9 40,609,321 - 40,609,381   EPDNEW Additional Information External Database Links Database Acc Id Source(s) Ensembl Genes ENSMUSG00000015656 ENTREZGENE Ensembl Protein ENSMUSP00000015800 ENTREZGENE Ensembl Transcript ENSMUST00000015800 ENTREZGENE Entrez Gene 15481 ENTREZGENE Germonline ENSMUSG00000015656 HomoloGene Group ID 68524 ENTREZGENE InterPro Heat_shock_70_CS UniProtKB/Swiss-Prot   Hsp_70 UniProtKB/Swiss-Prot IPI IPI00323357 UniProtKB/Swiss-Prot   IPI00885277 UniProtKB/TrEMBL   IPI00886297 UniProtKB/TrEMBL   IPI00886370 UniProtKB/TrEMBL KEGG Report mmu:15481 ENTREZGENE, UniProtKB/Swiss-Prot MGD MGI:105384 ENTREZGENE Pfam HSP70 UniProtKB/Swiss-Prot PRINTS HEATSHOCK70 UniProtKB/Swiss-Prot PROSITE HSP70_1 UniProtKB/Swiss-Prot   HSP70_2 UniProtKB/Swiss-Prot   HSP70_3 UniProtKB/Swiss-Prot UniGene Mm.290774 ENTREZGENE   Mm.336743 ENTREZGENE   Mm.351377 ENTREZGENE   Mm.412745 ENTREZGENE   Mm.485345 ENTREZGENE UniProt D3YW43_MOUSE UniProtKB/TrEMBL   D3Z5E2_MOUSE UniProtKB/TrEMBL   HSP7C_MOUSE UniProtKB/Swiss-Prot   Q3KQJ4_MOUSE UniProtKB/TrEMBL   Q3TB63_MOUSE UniProtKB/TrEMBL   Q3TEK2_MOUSE UniProtKB/TrEMBL   Q3TF16_MOUSE UniProtKB/TrEMBL   Q3TH04_MOUSE UniProtKB/TrEMBL   Q3TH56_MOUSE UniProtKB/TrEMBL   Q3TQ13_MOUSE UniProtKB/TrEMBL   Q3TRH3_MOUSE UniProtKB/TrEMBL   Q3TZJ3_MOUSE UniProtKB/TrEMBL   Q3U9L2_MOUSE UniProtKB/TrEMBL   Q3UBA6_MOUSE UniProtKB/TrEMBL   Q3UBR0_MOUSE UniProtKB/TrEMBL   Q3UDS0_MOUSE UniProtKB/TrEMBL   Q3ULM1_MOUSE UniProtKB/TrEMBL   Q3UXU1_MOUSE UniProtKB/TrEMBL   Q504P4_MOUSE UniProtKB/TrEMBL   Q9QZ38_MOUSE UniProtKB/TrEMBL

More on Hspa8 Entrez Gene Ensembl Gene Genome Browser MGI Report NCBI Map Viewer Vista Vista + UCSC RGD Object Information RGD ID: 10733 Created: 2000-05-25 Species: Mus musculus Last Modified: 2013-04-23 Status: ACTIVE