Trim32 (tripartite motif-containing 32) - Rat Genome Database

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Gene: Trim32 (tripartite motif-containing 32) Mus musculus
Analyze
Symbol: Trim32
Name: tripartite motif-containing 32
RGD ID: 1313151
MGI Page MGI
Description: Enables several functions, including identical protein binding activity; translation initiation factor binding activity; and ubiquitin protein ligase activity. Involved in several processes, including negative regulation of fibroblast proliferation; positive regulation of cell differentiation; and response to tumor necrosis factor. Acts upstream of or within several processes, including muscle cell cellular homeostasis; positive regulation of cytokine-mediated signaling pathway; and protein ubiquitination. Located in nucleus and striated muscle myosin thick filament. Is expressed in central nervous system and genitourinary system. Used to study autosomal recessive limb-girdle muscular dystrophy type 2H. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome; Bardet-Biedl syndrome 11; autosomal recessive limb-girdle muscular dystrophy type 2H; and muscular dystrophy. Orthologous to human TRIM32 (tripartite motif containing 32).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1810045E12Rik; 3f3; BBS1; BBS11; bM468K2.2 (tripartite motif protein 32); E3 ubiquitin-protein ligase TRIM32; RING-type E3 ubiquitin transferase TRIM32; tripartite motif protein 32; tripartite motif-containing protein 32; Zfp11; Zfp117; zinc finger protein 117
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39465,523,223 - 65,534,477 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl465,523,223 - 65,534,475 (+)EnsemblGRCm39 Ensembl
GRCm38465,604,986 - 65,616,240 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl465,604,986 - 65,616,238 (+)EnsemblGRCm38mm10GRCm38
MGSCv37465,266,020 - 65,277,274 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36465,091,379 - 65,102,599 (+)NCBIMGSCv36mm8
Celera464,238,387 - 64,249,387 (+)NCBICelera
Cytogenetic Map4C1NCBI
cM Map434.43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin ubiquitination  (IDA)
autophagosome assembly  (ISO)
axon development  (IMP)
fat cell differentiation  (IEP)
free ubiquitin chain polymerization  (ISO)
innate immune response  (ISO)
muscle cell cellular homeostasis  (IMP)
negative regulation of cilium assembly  (ISO)
negative regulation of fibroblast proliferation  (IEP)
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage  (ISO)
negative regulation of keratinocyte apoptotic process  (NAS)
negative regulation of toll-like receptor 4 signaling pathway  (ISO)
negative regulation of viral transcription  (ISO)
positive regulation of autophagosome assembly  (ISO)
positive regulation of autophagy  (ISO)
positive regulation of canonical NF-kappaB signal transduction  (ISO)
positive regulation of cell cycle  (ISO)
positive regulation of cell growth  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of cell motility  (IDA)
positive regulation of chemokine (C-C motif) ligand 20 production  (IMP)
positive regulation of interleukin-17-mediated signaling pathway  (IMP)
positive regulation of neurogenesis  (IDA)
positive regulation of neuron differentiation  (IDA)
positive regulation of protein catabolic process  (IDA)
positive regulation of proteolysis  (ISO)
positive regulation of striated muscle cell differentiation  (IMP)
positive regulation of tumor necrosis factor-mediated signaling pathway  (IMP)
protein K48-linked ubiquitination  (IBA)
protein K63-linked ubiquitination  (ISO)
protein polyubiquitination  (IMP,ISO)
protein ubiquitination  (IDA,ISO)
response to oxidative stress  (ISO)
response to starvation  (ISO)
response to tumor necrosis factor  (IDA)
response to UV  (IDA)
suppression of viral release by host  (ISO)
tissue homeostasis  (IMP)
ubiquitin-dependent protein catabolic process  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11). Chiang AP, etal., Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6287-92. Epub 2006 Apr 10.
2. Limb-girdle muscular dystrophy type 2H associated with mutation in TRIM32, a putative E3-ubiquitin-ligase gene. Frosk P, etal., Am J Hum Genet. 2002 Mar;70(3):663-72. Epub 2002 Jan 29.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:9989976   PMID:10229796   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11331580   PMID:12466851   PMID:12477932   PMID:12520002  
PMID:14578165   PMID:15489334   PMID:15618518   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16243356   PMID:16783635   PMID:16816390   PMID:16944949   PMID:17379567   PMID:18287559  
PMID:18632609   PMID:19155210   PMID:19269368   PMID:20054338   PMID:21267068   PMID:21677750   PMID:21732497   PMID:21775502   PMID:21873635   PMID:22299041   PMID:22505452   PMID:22908310  
PMID:23444366   PMID:23828567   PMID:24357807   PMID:24567360   PMID:24839933   PMID:25146927   PMID:25701873   PMID:25722370   PMID:25852471   PMID:26057645   PMID:26307407   PMID:26418459  
PMID:26496610   PMID:26884348   PMID:27325702   PMID:27339877   PMID:27720760   PMID:28190767   PMID:28378742   PMID:28508149   PMID:28514764   PMID:28933219   PMID:28954259   PMID:29899379  
PMID:30208054   PMID:31123703   PMID:31138677   PMID:31527798   PMID:31988176   PMID:32219328   PMID:32325033   PMID:32581705   PMID:32968282   PMID:33096083   PMID:34321999   PMID:34421574  
PMID:34783942   PMID:35159260   PMID:36374170  


Genomics

Comparative Map Data
Trim32
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39465,523,223 - 65,534,477 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl465,523,223 - 65,534,475 (+)EnsemblGRCm39 Ensembl
GRCm38465,604,986 - 65,616,240 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl465,604,986 - 65,616,238 (+)EnsemblGRCm38mm10GRCm38
MGSCv37465,266,020 - 65,277,274 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36465,091,379 - 65,102,599 (+)NCBIMGSCv36mm8
Celera464,238,387 - 64,249,387 (+)NCBICelera
Cytogenetic Map4C1NCBI
cM Map434.43NCBI
TRIM32
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389116,687,305 - 116,701,299 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9116,687,305 - 116,701,300 (+)EnsemblGRCh38hg38GRCh38
GRCh379119,449,584 - 119,463,578 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369118,489,402 - 118,503,400 (+)NCBINCBI36Build 36hg18NCBI36
Build 349116,529,162 - 116,542,582NCBI
Celera990,097,223 - 90,111,221 (+)NCBICelera
Cytogenetic Map9q33.1NCBI
HuRef989,054,928 - 89,068,929 (+)NCBIHuRef
CHM1_19119,596,015 - 119,610,013 (+)NCBICHM1_1
T2T-CHM13v2.09128,880,322 - 128,894,320 (+)NCBIT2T-CHM13v2.0
Trim32
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8584,020,604 - 84,031,483 (+)NCBIGRCr8
mRatBN7.2579,005,139 - 79,016,615 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl578,999,389 - 79,022,018 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx581,389,235 - 81,400,062 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0583,206,527 - 83,217,355 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0583,182,098 - 83,192,925 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0581,431,554 - 81,449,023 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl581,431,600 - 81,442,451 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0585,530,347 - 85,541,240 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4582,380,439 - 82,391,290 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1582,385,551 - 82,396,402 (+)NCBI
Celera577,919,712 - 77,930,564 (+)NCBICelera
Cytogenetic Map5q24NCBI
Trim32
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541911,151,751 - 11,168,041 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541911,151,751 - 11,168,046 (-)NCBIChiLan1.0ChiLan1.0
TRIM32
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21122,644,786 - 22,658,273 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1922,647,147 - 22,660,624 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0987,819,723 - 87,838,684 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19116,173,546 - 116,187,300 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9116,183,746 - 116,185,707 (+)Ensemblpanpan1.1panPan2
TRIM32
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11170,453,130 - 70,465,030 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1170,462,007 - 70,463,974 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1168,861,539 - 68,873,667 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01171,578,469 - 71,590,603 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1171,578,495 - 71,590,597 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11170,098,438 - 70,110,545 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01170,132,364 - 70,144,497 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01170,863,600 - 70,875,730 (+)NCBIUU_Cfam_GSD_1.0
Trim32
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947185,838,158 - 185,861,448 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364875,606,693 - 5,619,856 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364875,606,690 - 5,619,856 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM32
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1257,054,228 - 257,066,909 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11257,051,421 - 257,066,911 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21288,450,251 - 288,461,926 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRIM32
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11222,893,689 - 22,906,913 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1222,894,886 - 22,896,847 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603519,970,768 - 19,983,855 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trim32
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476018,585,279 - 18,599,659 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476018,577,764 - 18,600,869 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Trim32
274 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:948
Count of miRNA genes:428
Interacting mature miRNAs:516
Transcripts:ENSMUST00000050850, ENSMUST00000107366, ENSMUST00000155978, ENSMUST00000156922
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117072206Mouse
4141911W6q15_mweight 6 weeks QTL 15 (mouse)Not determined1789261688982216Mouse
39128211Lwq22_mliver weight QTL 22 (mouse)41789261688982216Mouse
1357453Kidq4_mkidney weight QTL 4 (mouse)Not determined41789261688982216Mouse
1301792Hdlq10_mHDL QTL 10 (mouse)Not determined43585970769859853Mouse
1300977Mopkd1_mmodifier of polycystic kidney disease progression 1 (mouse)Not determined43655083970550967Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000128993793Mouse
1302116Bbaa1_mB.burgdorferi-associated arthritis 1 (mouse)Not determined43825093072251078Mouse
1301786Bpq3_mblood pressure QTL 3 (mouse)Not determined44240224076402381Mouse
27226724Tibw2_mtibia width 2, proximal, 10 week (mouse)443000000108357197Mouse
1301941Mmtg1_mmodifier of mammary tumor growth 1 (mouse)Not determined44565844283099157Mouse
1558948Ath8_matherosclerosis 8 (mouse)Not determined445658442105156995Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138342753Mouse
12879977Bod2_mbone length and organs 2 (mouse)44628353180283678Mouse
10043880Adip23_madiposity 23 (mouse)Not determined44628353180283678Mouse
1300966Pabr2_mplasma apolipoprotein B (human) regulator 2 (mouse)Not determined446332646105801860Mouse
10449022Aanq1_maristolochic acid nephrotoxicity QTL 1 (mouse)44660382680603826Mouse
11532714Sluc43_msusceptibility to lung cancer 43 (mouse)446642108123127211Mouse
11532688Mh_mmodifier of hemostasis (mouse)44830477582304775Mouse
25314308Mlh1fc1_mMLH1 foci count 1 (mouse)44850000076918237Mouse
1301995Lprm1_mlymphoproliferation modifier 1 (mouse)Not determined45010026284100408Mouse
1301213Lgth3_mbody length 3 (mouse)Not determined45010026284100408Mouse
13207572Spir2_mStreptococcus pneumoniae infection resistance 2 (mouse)45068279588510637Mouse
1301033Abbp2_mA/J and C57BL/6 blood pressure 2 (mouse)Not determined45355083993763305Mouse
4141900Skts-fp1_mskin tumor susceptibility in FVB and PWK 1 (mouse)Not determined453550839124055180Mouse
26884434Zlq1_mzygomatic length QTL 1, 5 week (mouse)453700000103257197Mouse
13524838Hbasrq1a_mhabituation of the acoustic startle response QTL 1a (mouse)45447158988471589Mouse
13524841Hbasrq1_mhabituation of the acoustic startle response QTL 1 (mouse)45447158988471589Mouse
27095905Scvln3_msacral vertebrae length 2, 5 week (mouse)455600000128993793Mouse
27095934Ulnl2_mulna length 2, 5 week (mouse)45770000094788237Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
10043964Obq26_mobesity QTL 26 (mouse)Not determined45904725193047251Mouse
1357507Synch2_msynechia 2 (mouse)Not determined46014527794145424Mouse
1301190Cd4ts2_mCD4 T cell subset 2 (mouse)Not determined46014527794145424Mouse
1357443Lhyp_mlung hyperpermeability (mouse)Not determined46045401166764818Mouse
25394561Skmw53_mskeletal muscle weight 53, TA (mouse)46213829369838031Mouse
1357870Pfat1_mpredicted fat percentage 1 (mouse)Not determined46361952697619685Mouse
12879903Berr8_mberghei resistance locus 8 (mouse)46422246098222460Mouse
25394562Skmw54_mskeletal muscle weight 54, EDL (mouse)46516435766455211Mouse
27095939Ulnl9_mulna length 9, 16 week (mouse)465318237118857197Mouse

Markers in Region
UniSTS:234940  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38465,615,114 - 65,615,271UniSTSGRCm38
MGSCv37465,276,148 - 65,276,305UniSTSGRCm37
Celera464,248,261 - 64,248,418UniSTS
Cytogenetic Map4C1UniSTS
cM Map433.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001161782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_053084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006538235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006538236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006538237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006538238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030253765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF230385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF347694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK007783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL691456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX775777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC034104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE855341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG073447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY280460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000050850   ⟹   ENSMUSP00000062277
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl465,523,223 - 65,534,475 (+)Ensembl
GRCm38.p6 Ensembl465,604,986 - 65,616,238 (+)Ensembl
RefSeq Acc Id: ENSMUST00000107366   ⟹   ENSMUSP00000102989
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl465,523,223 - 65,534,475 (+)Ensembl
GRCm38.p6 Ensembl465,604,986 - 65,616,238 (+)Ensembl
RefSeq Acc Id: ENSMUST00000155978   ⟹   ENSMUSP00000119579
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl465,523,486 - 65,531,853 (+)Ensembl
GRCm38.p6 Ensembl465,605,249 - 65,613,616 (+)Ensembl
RefSeq Acc Id: ENSMUST00000156922   ⟹   ENSMUSP00000121949
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl465,523,486 - 65,531,993 (+)Ensembl
GRCm38.p6 Ensembl465,605,249 - 65,613,756 (+)Ensembl
RefSeq Acc Id: NM_001161782   ⟹   NP_001155254
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39465,523,223 - 65,534,477 (+)NCBI
GRCm38465,604,986 - 65,616,240 (+)ENTREZGENE
MGSCv37465,266,020 - 65,277,274 (+)RGD
Celera464,238,387 - 64,249,387 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_053084   ⟹   NP_444314
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39465,523,223 - 65,534,477 (+)NCBI
GRCm38465,604,986 - 65,616,240 (+)ENTREZGENE
MGSCv37465,266,020 - 65,277,274 (+)RGD
Celera464,238,387 - 64,249,387 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006538235   ⟹   XP_006538298
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39465,523,295 - 65,534,475 (+)NCBI
GRCm38465,605,058 - 65,616,238 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006538236   ⟹   XP_006538299
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39465,523,297 - 65,534,475 (+)NCBI
GRCm38465,605,316 - 65,616,238 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006538237   ⟹   XP_006538300
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39465,523,305 - 65,534,475 (+)NCBI
GRCm38465,605,076 - 65,616,238 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006538238   ⟹   XP_006538301
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39465,523,295 - 65,534,475 (+)NCBI
GRCm38465,605,059 - 65,616,238 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030253765   ⟹   XP_030109625
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39465,523,533 - 65,534,475 (+)NCBI
GRCm38465,605,316 - 65,616,238 (+)NCBI
Sequence:
RefSeq Acc Id: NP_444314   ⟸   NM_053084
- UniProtKB: Q8K055 (UniProtKB/Swiss-Prot),   Q8CH72 (UniProtKB/Swiss-Prot),   Q3TLR3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001155254   ⟸   NM_001161782
- UniProtKB: Q8K055 (UniProtKB/Swiss-Prot),   Q8CH72 (UniProtKB/Swiss-Prot),   Q3TLR3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006538298   ⟸   XM_006538235
- Peptide Label: isoform X1
- UniProtKB: Q8K055 (UniProtKB/Swiss-Prot),   Q8CH72 (UniProtKB/Swiss-Prot),   Q3TLR3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006538301   ⟸   XM_006538238
- Peptide Label: isoform X1
- UniProtKB: Q8K055 (UniProtKB/Swiss-Prot),   Q8CH72 (UniProtKB/Swiss-Prot),   Q3TLR3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006538300   ⟸   XM_006538237
- Peptide Label: isoform X1
- UniProtKB: Q8K055 (UniProtKB/Swiss-Prot),   Q8CH72 (UniProtKB/Swiss-Prot),   Q3TLR3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006538299   ⟸   XM_006538236
- Peptide Label: isoform X1
- UniProtKB: Q8K055 (UniProtKB/Swiss-Prot),   Q8CH72 (UniProtKB/Swiss-Prot),   Q3TLR3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030109625   ⟸   XM_030253765
- Peptide Label: isoform X1
- UniProtKB: Q8CH72 (UniProtKB/Swiss-Prot),   Q8K055 (UniProtKB/Swiss-Prot),   Q3TLR3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000062277   ⟸   ENSMUST00000050850
RefSeq Acc Id: ENSMUSP00000102989   ⟸   ENSMUST00000107366
RefSeq Acc Id: ENSMUSP00000121949   ⟸   ENSMUST00000156922
RefSeq Acc Id: ENSMUSP00000119579   ⟸   ENSMUST00000155978
Protein Domains
B box-type   RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8CH72-F1-model_v2 AlphaFold Q8CH72 1-655 view protein structure

Promoters
RGD ID:6836567
Promoter ID:MM_KWN:38033
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001161782,   NM_053084,   OTTMUST00000002483,   OTTMUST00000002484
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36465,265,761 - 65,266,261 (+)MPROMDB
RGD ID:6848801
Promoter ID:MM_TRO:6850
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:MTR004507.4.1031.3
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36465,274,416 - 65,274,916 (+)MPROMDB
RGD ID:6883674
Promoter ID:EPDNEW_M5288
Type:initiation region
Name:Trim32_1
Description:Mus musculus tripartite motif-containing 32 , transcript variant2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38465,605,009 - 65,605,069EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1917057 AgrOrtholog
Ensembl Genes ENSMUSG00000051675 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000050850 ENTREZGENE
  ENSMUST00000050850.14 UniProtKB/Swiss-Prot
  ENSMUST00000107366 ENTREZGENE
  ENSMUST00000107366.2 UniProtKB/Swiss-Prot
  ENSMUST00000155978.2 UniProtKB/TrEMBL
  ENSMUST00000156922.2 UniProtKB/TrEMBL
Gene3D-CATH 2.120.10.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro 6-blade_b-propeller_TolB-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NHL_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRIM32_Bbox1_Znf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf-RING_LisH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_B-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:69807 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1917057 ENTREZGENE
NCBI Gene 69807 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE TRIM32 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRIPARTITE MOTIF-CONTAINING PROTEIN 2-LIKE PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam NHL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-RING_UBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Trim32 PhenoGen
PROSITE NHL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_BBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP B-box zinc-binding domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NHL repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RING/U-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2AGS0_MOUSE UniProtKB/TrEMBL
  A2AGS1_MOUSE UniProtKB/TrEMBL
  Q3TLR3 ENTREZGENE, UniProtKB/TrEMBL
  Q8CH72 ENTREZGENE
  Q8K055 ENTREZGENE
  Q99PN6_MOUSE UniProtKB/TrEMBL
  TRI32_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q8K055 UniProtKB/Swiss-Prot