Gene: Mpo (myeloperoxidase)  Mus musculus Symbol: Mpo Name: myeloperoxidase Description: ENCODES a protein that exhibits peroxidase activity; heparin binding (ortholog); INVOLVED IN defense response to fungus; hydrogen peroxide catabolic process; hypochlorous acid biosynthetic process; PARTICIPATES IN interleukin-23 signaling pathway; ASSOCIATED WITH abnormal metabolism; abnormal muscle fiber morphology; abnormal neutrophil physiology; ASSOCIATED WITH Acute Lung Injury; Glomerulonephritis; Kidney Reperfusion Injury; FOUND IN mitochondrion; extracellular space (ortholog); secretory granule (ortholog); INTERACTS WITH (R)-camphor; 1,7-dimethylxanthine; 1-chloro-2,4,6-trinitrobenzene Type: protein-coding RefSeq Status: VALIDATED Also known as: KIAA4033; mKIAA4033; myeloperoxidase; OTTMUSP00000001371; OTTMUSP00000034233 Orthologs: Homo sapiens : MPO (myeloperoxidase)  HGNC Rattus norvegicus : Mpo (myeloperoxidase) Latest Assembly: Mouse Genome Assembly Build 37 Position: Map Chr Position Strand Source Mouse Genome Assembly GRCm38 11 87,793,784 - 87,804,412 + NCBI Mouse cM Map 11 52.22   NCBI Mouse Celera Assembly 11 97,389,547 - 97,400,150 + NCBI Mouse Genome Assembly Build 37 11 87,607,286 - 87,617,914 + NCBI Mouse Genome Assembly Build 36.1 11 87,607,083 - 87,617,899 + NCBI Mouse Cytogenetic Map 11 C   NCBI Model Launch Genome Browser (GBrowse) Annotation    (Toggle Detail/Summary View) Disease Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) Acute Kidney Injury   ISS RGD:1592081 6909185   RGD   Acute Kidney Injury   ISS RGD:1346384 6909168 DNA:haplotye: : RGD   Acute Lung Injury   IEP   6909173 associated with Kidney Reperfusion Injury; more ... RGD   Alzheimer Disease   ISS RGD:1346384 7240710   OMIM   Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Disease_progression ISS RGD:1346384 7174703   RGD   Asthma Susceptibility ISS RGD:1346384 5130989 DNA:polymorphism: :−463G > A (human) RGD   Asthma   ISS RGD:1346384 5130994 protein:increased expression:serum RGD   Bronchiolitis, Viral   ISS RGD:1346384 5130995   RGD   Bronchitis, Chronic   ISS RGD:1592081 5130990 protein:increased expression:lung RGD   Burns   ISS RGD:1592081 6909170 protein:increased activity:kidney, lung RGD   Cardiovascular Diseases   ISS RGD:1346384 6909169 associated with Kidney Failure, chronic; more ... RGD   Contrast-Induced Nephropathy   ISS RGD:1592081 6909183   RGD   Cystic Fibrosis   ISS RGD:1346384 5130986   RGD   Cystic Fibrosis Severity ISS RGD:1346384 5130968 DNA:polymorphism:promoter:-463G>A (human) RGD   Cystitis   ISS RGD:1592081 7174704 protein:increased activity:bladder RGD   Diabetes Mellitus, Experimental   ISS RGD:1592081 2317971 protein:increased activity:liver: RGD   Enteritis   ISS RGD:1592081 6909182 protein:increased activity:intestine mucosa RGD   Glomerulonephritis   IPM   7174702   RGD   Glomerulonephritis Disease_progression ISS RGD:1346384 7174705   RGD   Hypertension, Renovascular   ISS RGD:1592081 7174698 protein:increased activity:heart, brain, kidney RGD   Kidney Calculi   ISS RGD:1346384 7174700 protein:increased activity:blood RGD   Kidney Failure, Chronic Disease_progression ISS RGD:1346384 6909184   RGD   Kidney Reperfusion Injury   IPM   7174699   RGD   Kidney Reperfusion Injury   ISS RGD:1592081 6909167 protein:increased activity:kidney RGD   Lung Diseases   ISS RGD:1346384 5130962 acute lung injury RGD   Lung Diseases, Interstitial   ISS RGD:1346384 5130207 associated with Sclerodema, systemic; more ... RGD   Lung Neoplasms   ISS RGD:1346384 5131088 associated with Respiratory Tract Diseases RGD   Lupus Nephritis Susceptibility ISS RGD:1346384 7174701 DNA:polymorphism: :−463G > A (human) RGD   Multiple Sclerosis   ISS   1358499   RGD   Myeloperoxidase Deficiency   ISS RGD:1346384 7240710   OMIM   Myocardial Ischemia   ISS RGD:1346384 5130961 Acute Coronary Syndrome; more ... RGD   Pancreatic Neoplasms Resistance ISS RGD:1346384 2317406 DNA:polymorphism:promoter:-463G>A (human) RGD   Pleurisy   IEP   5130991 protein:increased activity:lung RGD   Pneumonia, Bacterial   ISS RGD:1346384 5130992 protein:increased activity:bronchoalveolar lavage Fluid: RGD   Pulmonary Disease, Chronic Obstructive   ISS RGD:1592081 5130997 protein:increased activity:plasma RGD   Pulmonary Disease, Chronic Obstructive Severity ISS RGD:1346384 5130993 protein:increased expression:serum RGD   Reperfusion Injury   ISS RGD:1592081 5130958 protein:increased activity:lung RGD   Sepsis   IPM   5130966   RGD   Spinal Cord Injuries   ISS RGD:1592081 6909148 protein:increased activity:spinal cord RGD   Status Asthmaticus   ISS RGD:1346384 5130994 protein:increased expression:serum RGD   Vasculitis   ISS RGD:1346384 5130969 microscopic polyangiitis RGD   Gene-Chemical Interaction Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) (R)-camphor multiple interactions EXP   6480464 Camphor inhibits the reaction [cinnamic aldehyde results in increased activity of MPO protein] CTD PMID:21466812 (R)-carnitine multiple interactions ISO RGD:1592081 6480464 [Carboplatin co-treated with Carnitine deficiency] results in increased expression of MPO protein CTD PMID:18852009 (R)-carnitine multiple interactions ISO RGD:1592081 6480464 Acetaminophen promotes the reaction [Carnitine deficiency results in increased activity of MPO protein] CTD PMID:18597074 (R)-carnitine increases activity ISO RGD:1592081 6480464 Carnitine deficiency results in increased activity of MPO protein CTD PMID:18597074 (S)-colchicine multiple interactions ISO RGD:1592081 6480464 Colchicine inhibits the reaction [Ethanol results in increased activity of MPO protein] CTD PMID:22446813 (S)-nicotine decreases activity ISO RGD:1592081 6480464 Nicotine results in decreased activity of MPO protein CTD PMID:15976189 1,2-phenylenediamine multiple interactions ISO RGD:1346384 6480464 Tetradecanoylphorbol Acetate promotes the reaction [MPO protein results in increased oxidation of 1,2-diaminobenzene] CTD PMID:3030588 1,2-phenylenediamine increases oxidation ISO RGD:1346384 6480464 MPO protein results in increased oxidation of 1,2-diaminobenzene CTD PMID:3030588 1,7-dimethylxanthine multiple interactions EXP   6480464 1,7-dimethylxanthine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of MPO protein] CTD PMID:19962977 1-chloro-2,4,6-trinitrobenzene multiple interactions EXP   6480464 Cyclosporine inhibits the reaction [Picryl Chloride results in increased activity of MPO protein]; more ... CTD PMID:16442096 1-chloro-2,4,6-trinitrobenzene increases activity EXP   6480464 Picryl Chloride results in increased activity of MPO protein CTD PMID:16442096 1-chloro-2,4-dinitrobenzene multiple interactions ISO RGD:1592081 6480464 Curcumin inhibits the reaction [Dinitrochlorobenzene results in decreased activity of MPO protein]; more ... CTD PMID:17373747 1-chloro-2,4-dinitrobenzene decreases expression ISO RGD:1346384 6480464 Dinitrochlorobenzene results in decreased expression of MPO mRNA CTD PMID:17374397 1-chloro-2,4-dinitrobenzene decreases activity ISO RGD:1592081 6480464 Dinitrochlorobenzene results in decreased activity of MPO protein CTD PMID:17373747 1-naphthyl isothiocyanate increases activity EXP   6480464 1-Naphthylisothiocyanate results in increased activity of MPO protein CTD PMID:20133375 1-naphthyl isothiocyanate multiple interactions EXP   6480464 F3 mutant form inhibits the reaction [1-Naphthylisothiocyanate results in increased activity of MPO protein] CTD PMID:21070799 1-naphthyl isothiocyanate increases activity EXP   6480464 1-Naphthylisothiocyanate results in increased activity of MPO protein CTD PMID:20133375 PMID:21070799 1-naphthyl isothiocyanate increases activity ISO RGD:1592081 6480464 1-Naphthylisothiocyanate results in increased activity of MPO protein CTD PMID:18590720 PMID:18364083 1-naphthyl isothiocyanate multiple interactions ISO RGD:1592081 6480464 Dexamethasone affects the reaction [1-Naphthylisothiocyanate results in increased activity of MPO protein]; more ... CTD PMID:18590720 1-naphthyl isothiocyanate increases activity ISO RGD:1592081 6480464 1-Naphthylisothiocyanate results in increased activity of MPO protein CTD PMID:18364083 PMID:18590720 1-naphthyl isothiocyanate multiple interactions EXP   6480464 clopidogrel inhibits the reaction [1-Naphthylisothiocyanate results in increased activity of MPO protein] CTD PMID:20133375 17-HDoHE multiple interactions EXP   6480464 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; more ... CTD PMID:21724996 2,2',4,4'-tetrachlorobiphenyl increases secretion ISO RGD:1346384 6480464 2,4,2',4'-tetrachlorobiphenyl results in increased secretion of MPO protein CTD PMID:15673847 2,4,6-trinitrobenzenesulfonic acid increases activity EXP   6480464 Trinitrobenzenesulfonic Acid results in increased activity of MPO protein CTD PMID:17553498 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:1592081 6480464 resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:16474422 PMID:22029500 2,4,6-trinitrobenzenesulfonic acid increases activity ISO RGD:1592081 6480464 Trinitrobenzenesulfonic Acid results in increased activity of MPO protein CTD PMID:11698051 more ... 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:1592081 6480464 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:16804969 more ... 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:1592081 6480464 4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; more ... CTD PMID:22119283 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:1592081 6480464 Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:22410118 2,4,6-trinitrobenzenesulfonic acid increases activity ISO RGD:1592081 6480464 Trinitrobenzenesulfonic Acid results in increased activity of MPO protein CTD PMID:11698051 more ... 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:1592081 6480464 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:16867261 more ... 2,4,6-trinitrobenzenesulfonic acid increases activity ISO RGD:1592081 6480464 Trinitrobenzenesulfonic Acid results in increased activity of MPO protein CTD PMID:22039321 more ... 2,4,6-trinitrobenzenesulfonic acid increases activity ISO RGD:1592081 6480464 Trinitrobenzenesulfonic Acid results in increased activity of MPO protein CTD PMID:16474422 more ... 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:1592081 6480464 Cadmium Chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; more ... CTD PMID:17292349 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:1592081 6480464 Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:21893697 PMID:22039321 2,4,6-trinitrobenzenesulfonic acid increases activity ISO RGD:1592081 6480464 Trinitrobenzenesulfonic Acid results in increased activity of MPO protein CTD PMID:17276891 more ... 2,4,6-trinitrobenzenesulfonic acid increases activity ISO RGD:1592081 6480464 Trinitrobenzenesulfonic Acid results in increased activity of MPO protein CTD PMID:11698051 more ... 2,4,6-trinitrobenzenesulfonic acid increases activity EXP   6480464 Trinitrobenzenesulfonic Acid results in increased activity of MPO protein CTD PMID:17553498 PMID:21724996 2,4,6-trinitrobenzenesulfonic acid increases activity ISO RGD:1592081 6480464 Trinitrobenzenesulfonic Acid results in increased activity of MPO protein CTD PMID:17276891 more ... 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:1592081 6480464 Dinoprostone analog inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; more ... CTD PMID:22039321 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:1592081 6480464 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:17276891 more ... 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:1592081 6480464 celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:21893697 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:1592081 6480464 Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:22039321 PMID:21893697 2,4,6-trinitrobenzenesulfonic acid increases activity EXP   6480464 Trinitrobenzenesulfonic Acid results in increased activity of MPO protein CTD PMID:21724996 PMID:17553498 2,4,6-trinitrobenzenesulfonic acid multiple interactions EXP   6480464 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; more ... CTD PMID:21724996 2,4,6-trinitrobenzenesulfonic acid increases expression ISO RGD:1592081 6480464 Trinitrobenzenesulfonic Acid results in increased expression of MPO protein CTD PMID:17991707 2,4,6-trinitrobenzenesulfonic acid increases activity ISO RGD:1592081 6480464 Trinitrobenzenesulfonic Acid results in increased activity of MPO protein CTD PMID:16474422 more ... 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:1592081 6480464 resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:16474422 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:1592081 6480464 montelukast inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; more ... CTD PMID:11698051 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:1592081 6480464 Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:16867261 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:1592081 6480464 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:16804969 more ... 2,4-dichloroaniline multiple interactions ISO RGD:1346384 6480464 [MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 2,4-dichloroaniline; more ... CTD PMID:20199096 2,4-dimethylaniline multiple interactions ISO RGD:1346384 6480464 [MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 2,4-xylidine; more ... CTD PMID:20199096 2,6-dimethylaniline multiple interactions ISO RGD:1346384 6480464 [[MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 2,6-xylidine] which results in increased expression of MPO protein modified form CTD PMID:20199096 2-amino-2-deoxy-D-glucopyranose decreases activity ISO RGD:1592081 6480464 Glucosamine results in decreased activity of MPO protein CTD PMID:19098112 2-naphthylamine affects metabolic processing ISO RGD:1346384 6480464 MPO protein affects the metabolism of 2-Naphthylamine CTD PMID:9288889 3,3',5-triiodo-L-thyronine multiple interactions ISO RGD:1592081 6480464 [Triiodothyronine co-treated with Lindane] results in increased activity of MPO protein CTD PMID:7503757 3,4-dichloroaniline multiple interactions ISO RGD:1346384 6480464 [MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 3,4-dichloroaniline; more ... CTD PMID:20199096 3,4-dimethylaniline multiple interactions ISO RGD:1346384 6480464 [MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 3,4-xylidine; more ... CTD PMID:20199096 3-aminobenzamide multiple interactions EXP   6480464 3-aminobenzamide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of MPO protein] CTD PMID:19962977 4-(ethoxymethylene)-2-phenyloxazol-5-one decreases expression ISO RGD:1346384 6480464 Oxazolone results in decreased expression of MPO mRNA CTD PMID:17374397 4-(ethoxymethylene)-2-phenyloxazol-5-one multiple interactions EXP   6480464 tetramethylpyrazine inhibits the reaction [Oxazolone results in increased expression of MPO protein] CTD PMID:22200888 4-(ethoxymethylene)-2-phenyloxazol-5-one increases expression EXP   6480464 Oxazolone results in increased expression of MPO protein CTD PMID:22200888 4-chloroaniline multiple interactions ISO RGD:1346384 6480464 [MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 4-chloroaniline; more ... CTD PMID:20199096 4-fluoroaniline multiple interactions ISO RGD:1346384 6480464 [[MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 4-fluoroaniline] which results in increased expression of MPO protein modified form CTD PMID:20199096 4-nitroaniline multiple interactions ISO RGD:1346384 6480464 [[MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 4-nitroaniline] which results in increased expression of MPO protein modified form CTD PMID:20199096 5-aza-2'-deoxycytidine multiple interactions ISO RGD:1346384 6480464 [decitabine co-treated with trichostatin A] results in increased expression of MPO mRNA CTD PMID:17185465 6-propyl-2-thiouracil decreases activity ISO RGD:1346384 6480464 Propylthiouracil results in decreased activity of MPO protein CTD PMID:17070108 7,12-dimethyltetraphene multiple interactions EXP   6480464 [9,10-Dimethyl-1,2-benzanthracene co-treated with cumene hydroperoxide] results in increased activity of MPO protein CTD PMID:14972014 acetaldehyde multiple interactions ISO RGD:1346384 6480464 [MPO protein co-treated with XDH protein co-treated with Acetaldehyde co-treated with Serotonin] affects the metabolism of and binds to GAPDH protein; more ... CTD PMID:23009681 acetylsalicylic acid multiple interactions ISO RGD:1592081 6480464 Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:22039321 PMID:21893697 acetylsalicylic acid multiple interactions ISO RGD:1592081 6480464 Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:21893697 PMID:22039321 albuterol multiple interactions ISO RGD:1346384 6480464 Ascorbic Acid inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Albuterol]; more ... CTD PMID:19462961 aldehydo-D-glucosamine decreases activity ISO RGD:1592081 6480464 Glucosamine results in decreased activity of MPO protein CTD PMID:19098112 all-trans-retinoic acid multiple interactions ISO RGD:1346384 6480464 [Tretinoin co-treated with arsenic trioxide co-treated with Butyrates] results in decreased expression of MPO mRNA; more ... CTD PMID:12130515 all-trans-retinoic acid decreases expression ISO RGD:1346384 6480464 Tretinoin results in decreased expression of MPO protein CTD PMID:11133770 all-trans-retinoic acid multiple interactions ISO RGD:1346384 6480464 arsenic trioxide inhibits the reaction [Tretinoin results in decreased expression of MPO protein] CTD PMID:11133770 all-trans-retinoic acid decreases expression ISO RGD:1346384 6480464 Tretinoin results in decreased expression of MPO mRNA CTD PMID:16140954 PMID:17218384 all-trans-retinoic acid decreases expression ISO RGD:1346384 6480464 Tretinoin results in decreased expression of MPO mRNA CTD PMID:17218384 PMID:16140954 all-trans-retinoic acid multiple interactions ISO RGD:1346384 6480464 Thiophenes analog promotes the reaction [Tretinoin results in decreased expression of MPO mRNA] CTD PMID:16140954 allopurinol multiple interactions ISO RGD:1592081 6480464 Allopurinol inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:12566098 aluminium atom increases expression ISO RGD:1346384 6480464 Aluminum results in increased expression of MPO protein CTD PMID:17402216 aluminium(0) increases expression ISO RGD:1346384 6480464 Aluminum results in increased expression of MPO protein CTD PMID:17402216 amifostine multiple interactions EXP   6480464 Amifostine inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein] CTD PMID:19010997 aminoglutethimide multiple interactions ISO RGD:1346384 6480464 [[MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of Aminoglutethimide] which results in increased expression of MPO protein modified form CTD PMID:20199096 aminoguanidine multiple interactions ISO RGD:1592081 6480464 pimagedine promotes the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:18209962 aminoguanidine multiple interactions ISO RGD:1592081 6480464 pimagedine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11713966 amiodarone multiple interactions ISO RGD:1592081 6480464 Amiodarone promotes the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:18087811 ammonia increases activity EXP   6480464 Ammonia results in increased activity of MPO protein CTD PMID:12374618 ampicillin multiple interactions ISO RGD:1592081 6480464 Ampicillin inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11686837 more ... ampicillin multiple interactions ISO RGD:1592081 6480464 Ampicillin inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11686837 more ... ampicillin multiple interactions ISO RGD:1592081 6480464 Ampicillin inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11991626 more ... ampicillin multiple interactions ISO RGD:1592081 6480464 Ampicillin inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:18306037 more ... aniline multiple interactions ISO RGD:1346384 6480464 [[MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of aniline] which results in increased expression of MPO protein modified form CTD PMID:20199096 apocynin decreases expression EXP   6480464 acetovanillone results in decreased expression of MPO protein CTD PMID:19417757 arachidonic acid multiple interactions EXP   6480464 5-((1,5-bis(4-methoxyphenyl)pyrazol-3-yl)dimethoxymethyl)-2-chlorobenzamide inhibits the reaction [Arachidonic Acid results in increased expression of MPO protein] CTD PMID:9831321 arachidonic acid increases secretion ISO RGD:1346384 6480464 Arachidonic Acid results in increased secretion of MPO protein CTD PMID:3111576 arachidonic acid increases expression EXP   6480464 Arachidonic Acid results in increased expression of MPO protein CTD PMID:9831321 arsenic atom increases response to substance ISO RGD:1346384 6480464 MPO gene polymorphism results in increased susceptibility to Arsenic CTD PMID:14580687 arsenite(3-) decreases expression EXP   6480464 arsenite results in decreased expression of MPO mRNA CTD PMID:15894712 arsenite(3-) multiple interactions EXP   6480464 [arsenite co-treated with Benzo(a)pyrene] results in decreased expression of MPO mRNA CTD PMID:15894712 asbestos increases response to substance ISO RGD:1346384 6480464 MPO gene polymorphism results in increased susceptibility to Asbestos CTD PMID:12111688 benzene affects response to substance ISO RGD:1346384 6480464 MPO protein affects the susceptibility to Benzene CTD PMID:14761515 benzene increases expression EXP   6480464 Benzene results in increased expression of MPO mRNA CTD PMID:12928149 benzene increases metabolic processing ISO RGD:1346384 6480464 MPO protein results in increased metabolism of Benzene CTD PMID:17885617 benzene increases response to substance ISO RGD:1346384 6480464 MPO gene SNP results in increased susceptibility to Benzene CTD PMID:15576619 benzene affects response to substance ISO RGD:1346384 6480464 MPO gene polymorphism affects the susceptibility to Benzene CTD PMID:18214807 benzo[a]pyrene multiple interactions EXP   6480464 [arsenite co-treated with Benzo(a)pyrene] results in decreased expression of MPO mRNA CTD PMID:15894712 benzo[a]pyrene decreases expression EXP   6480464 Benzo(a)pyrene results in decreased expression of MPO mRNA CTD PMID:15894712 benzo[a]pyrene multiple interactions EXP   6480464 [Benzo(a)pyrene co-treated with XPA gene mutant form co-treated with TRP53 gene mutant form] results in increased expression of MPO mRNA CTD PMID:21715664 berberine multiple interactions EXP   6480464 Berberine inhibits the reaction [Lipopolysaccharides results in increased expression of MPO protein] CTD PMID:21963898 beta-D-glucosamine decreases activity ISO RGD:1592081 6480464 Glucosamine results in decreased activity of MPO protein CTD PMID:19098112 biphenyl-4-amine affects metabolic processing ISO RGD:1346384 6480464 MPO protein affects the metabolism of 4-biphenylamine CTD PMID:9288889 bis(2-chloroethyl) sulfide increases expression EXP   6480464 Mustard Gas results in increased expression of MPO protein CTD PMID:11428626 bis(2-chloroethyl) sulfide decreases expression EXP   6480464 Mustard Gas results in decreased expression of MPO mRNA CTD PMID:18955075 bivalirudin decreases expression ISO RGD:1346384 6480464 bivalirudin results in decreased expression of MPO protein CTD PMID:18701766 bleomycin A2 increases activity EXP   6480464 Bleomycin results in increased activity of MPO protein CTD PMID:17118201 PMID:16317386 bleomycin A2 multiple interactions ISO RGD:1592081 6480464 resveratrol inhibits the reaction [Bleomycin results in increased activity of MPO protein] CTD PMID:17035056 bleomycin A2 increases activity ISO RGD:1592081 6480464 Bleomycin results in increased activity of MPO protein CTD PMID:17035056 bleomycin A2 increases activity EXP   6480464 Bleomycin results in increased activity of MPO protein CTD PMID:16317386 PMID:17118201 bleomycin A2 multiple interactions EXP   6480464 verlukast inhibits the reaction [Bleomycin results in increased activity of MPO protein]; more ... CTD PMID:17118201 bleomycin A2 multiple interactions EXP   6480464 pirinixic acid inhibits the reaction [Bleomycin results in increased activity of MPO protein] CTD PMID:16317386 budesonide multiple interactions ISO RGD:1592081 6480464 Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli 0111 B4 results in increased expression of MPO protein] CTD PMID:15734790 buta-1,3-diene increases oxidation ISO RGD:1346384 6480464 MPO protein results in increased oxidation of 1,3-butadiene CTD PMID:1328183 cadmium dichloride increases activity EXP   6480464 Cadmium Chloride results in increased activity of MPO protein CTD PMID:19748544 cadmium dichloride increases activity EXP   6480464 Cadmium Chloride results in increased activity of MPO protein CTD PMID:16413704 PMID:19748544 cadmium dichloride increases activity EXP   6480464 Cadmium Chloride results in increased activity of MPO protein CTD PMID:19748544 PMID:16413704 cadmium dichloride multiple interactions ISO RGD:1592081 6480464 Cadmium Chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:17292349 cadmium dichloride multiple interactions EXP   6480464 Carnosine inhibits the reaction [Cadmium Chloride results in increased activity of MPO protein] CTD PMID:19748544 camphor multiple interactions EXP   6480464 Camphor inhibits the reaction [cinnamic aldehyde results in increased activity of MPO protein] CTD PMID:21466812 candesartan multiple interactions ISO RGD:1592081 6480464 candesartan inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17763956 capsaicin affects activity ISO RGD:1592081 6480464 Capsaicin affects the activity of MPO protein CTD PMID:12893632 capsaicin multiple interactions ISO RGD:1592081 6480464 Capsaicin inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:10671773 capsaicin multiple interactions ISO RGD:1592081 6480464 Capsaicin inhibits the reaction [Diquat results in increased activity of MPO protein]; more ... CTD PMID:15046732 capsaicin multiple interactions ISO RGD:1592081 6480464 Indomethacin inhibits the reaction [Capsaicin affects the activity of MPO protein] CTD PMID:12893632 capsaicin decreases expression ISO RGD:1592081 6480464 Capsaicin results in decreased expression of MPO protein CTD PMID:12024109 capsaicin multiple interactions ISO RGD:1592081 6480464 Capsaicin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein] CTD PMID:15573930 carboplatin multiple interactions ISO RGD:1592081 6480464 [Carboplatin co-treated with Carnitine deficiency] results in increased expression of MPO protein CTD PMID:18852009 carnosine multiple interactions EXP   6480464 Carnosine inhibits the reaction [Cadmium Chloride results in increased activity of MPO protein] CTD PMID:19748544 carrageenan multiple interactions ISO RGD:1592081 6480464 Carrageenan inhibits the reaction [Raloxifene results in increased activity of MPO protein] CTD PMID:15860553 carrageenan increases activity ISO RGD:1592081 6480464 Carrageenan results in increased activity of MPO protein CTD PMID:15860553 carvedilol multiple interactions EXP   6480464 carvedilol inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of MPO protein] CTD PMID:17159805 carvedilol multiple interactions ISO RGD:1346384 6480464 carvedilol inhibits the reaction [Calcimycin results in increased secretion of MPO protein] CTD PMID:18987595 carvedilol multiple interactions ISO RGD:1346384 6480464 carvedilol inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased secretion of MPO protein]; more ... CTD PMID:16601795 PMID:18987595 carvedilol multiple interactions ISO RGD:1346384 6480464 carvedilol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MPO protein] CTD PMID:18987595 PMID:16601795 celecoxib increases activity ISO RGD:1592081 6480464 celecoxib results in increased activity of MPO protein CTD PMID:15309881 celecoxib multiple interactions ISO RGD:1592081 6480464 celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:21893697 ceruletide increases expression EXP   6480464 Caerulein results in increased expression of MPO protein CTD PMID:17484889 ceruletide multiple interactions EXP   6480464 HU 211 inhibits the reaction [Caerulein results in increased expression of MPO protein] CTD PMID:17484889 chlorphenamine decreases activity ISO RGD:1592081 6480464 Chlorpheniramine results in decreased activity of MPO protein CTD PMID:16437673 chlorphenamine multiple interactions ISO RGD:1592081 6480464 Famotidine promotes the reaction [Chlorpheniramine results in decreased activity of MPO protein] CTD PMID:16437673 chondroitin sulfate multiple interactions ISO RGD:1592081 6480464 [Chondroitin Sulfates co-treated with Hyaluronic Acid] inhibits the reaction [Carbon Tetrachloride results in increased activity of MPO protein] CTD PMID:14697411 cis-caffeic acid multiple interactions EXP   6480464 caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [MPO protein results in increased metabolism of Hydrogen Peroxide]]; more ... CTD PMID:22036979 cisplatin affects response to substance ISO RGD:1346384 6480464 MPO gene polymorphism affects the susceptibility to Cisplatin CTD PMID:16785472 cisplatin increases activity ISO RGD:1592081 6480464 Cisplatin results in increased activity of MPO protein CTD PMID:20676799 cisplatin multiple interactions ISO RGD:1592081 6480464 pycnogenols inhibits the reaction [Cisplatin results in increased activity of MPO protein] CTD PMID:20676799 cocaine increases activity ISO RGD:1592081 6480464 Cocaine results in increased activity of MPO protein CTD PMID:17420087 copper atom decreases activity ISO RGD:1346384 6480464 Copper results in decreased activity of MPO protein CTD PMID:15557676 copper atom increases activity ISO RGD:1346384 6480464 Copper results in increased activity of MPO protein CTD PMID:15557676 copper(0) decreases activity ISO RGD:1346384 6480464 Copper results in decreased activity of MPO protein CTD PMID:15557676 copper(0) increases activity ISO RGD:1346384 6480464 Copper results in increased activity of MPO protein CTD PMID:15557676 crocetin multiple interactions EXP   6480464 crocetin inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein] CTD PMID:21925167 crocidolite asbestos increases activity EXP   6480464 Asbestos, Crocidolite results in increased activity of MPO protein CTD PMID:12160931 crocidolite asbestos increases activity ISO RGD:1592081 6480464 Asbestos, Crocidolite results in increased activity of MPO protein CTD PMID:12051993 crocidolite asbestos multiple interactions EXP   6480464 NOS2 gene mutant form inhibits the reaction [Asbestos, Crocidolite results in increased activity of MPO protein] CTD PMID:12160931 curcumin multiple interactions ISO RGD:1592081 6480464 Curcumin inhibits the reaction [Dinitrochlorobenzene results in decreased activity of MPO protein] CTD PMID:17373747 curcumin decreases activity ISO RGD:1346384 6480464 Curcumin analog results in decreased activity of MPO protein CTD PMID:23291280 curcumin multiple interactions ISO RGD:1592081 6480464 Curcumin inhibits the reaction [Methotrexate results in increased expression of MPO protein] CTD PMID:20885979 curcumin multiple interactions ISO RGD:1592081 6480464 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:16867261 more ... curcumin multiple interactions ISO RGD:1592081 6480464 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:17276891 more ... curcumin decreases activity ISO RGD:1592081 6480464 Curcumin results in decreased activity of MPO protein CTD PMID:17461496 curcumin multiple interactions ISO RGD:1592081 6480464 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:16804969 more ... curcumin multiple interactions ISO RGD:1592081 6480464 Curcumin inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17351913 cyclophosphamide increases activity ISO RGD:1592081 6480464 Cyclophosphamide results in increased activity of MPO protein CTD PMID:17979934 more ... cyclophosphamide increases activity ISO RGD:1592081 6480464 Cyclophosphamide results in increased activity of MPO protein CTD PMID:17979934 more ... cyclophosphamide increases activity ISO RGD:1592081 6480464 Cyclophosphamide results in increased activity of MPO protein CTD PMID:10749792 more ... cyclophosphamide increases activity ISO RGD:1592081 6480464 Cyclophosphamide results in increased activity of MPO protein CTD PMID:18710439 more ... cyclophosphamide multiple interactions ISO RGD:1592081 6480464 Rolipram inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein] CTD PMID:18710439 cyclophosphamide multiple interactions ISO RGD:1592081 6480464 Hemin inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein] CTD PMID:17979934 cyclosporin A multiple interactions EXP   6480464 Cyclosporine inhibits the reaction [Picryl Chloride results in increased activity of MPO protein] CTD PMID:16442096 cypermethrin increases expression EXP   6480464 cypermethrin results in increased expression of MPO mRNA CTD PMID:21142847 cysteamine multiple interactions ISO RGD:1592081 6480464 Omeprazole inhibits the reaction [Cysteamine results in increased expression of MPO protein]; more ... CTD PMID:20165931 cysteamine increases expression ISO RGD:1592081 6480464 Cysteamine results in increased expression of MPO protein CTD PMID:20165931 D-penicillamine decreases secretion ISO RGD:1346384 6480464 Penicillamine results in decreased secretion of MPO protein CTD PMID:6324512 dexamethasone multiple interactions EXP   6480464 Dexamethasone inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:15138204 dexamethasone multiple interactions ISO RGD:1592081 6480464 Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:16867261 dexamethasone multiple interactions ISO RGD:1592081 6480464 Dexamethasone inhibits the reaction [Paraquat results in increased activity of MPO protein] CTD PMID:17015168 dexamethasone multiple interactions ISO RGD:1592081 6480464 Dexamethasone affects the reaction [1-Naphthylisothiocyanate results in increased activity of MPO protein] CTD PMID:18590720 dexamethasone multiple interactions EXP   6480464 Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein] CTD PMID:21511011 dextran sulfate multiple interactions ISO RGD:1592081 6480464 Oligosaccharides inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein] CTD PMID:16375993 dextran sulfate multiple interactions EXP   6480464 monotropein inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein] CTD PMID:23261679 dextran sulfate increases activity EXP   6480464 Dextran Sulfate results in increased activity of MPO protein CTD PMID:20637373 more ... dextran sulfate increases expression EXP   6480464 Dextran Sulfate results in increased expression of MPO protein CTD PMID:23261717 dextran sulfate multiple interactions EXP   6480464 resveratrol inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein] CTD PMID:20637373 dextran sulfate increases activity EXP   6480464 Dextran Sulfate results in increased activity of MPO protein CTD PMID:20637373 PMID:21724996 dextran sulfate increases activity ISO RGD:1592081 6480464 Dextran Sulfate results in increased activity of MPO protein CTD PMID:15573930 more ... dextran sulfate increases activity ISO RGD:1592081 6480464 Dextran Sulfate results in increased activity of MPO protein CTD PMID:16375993 more ... dextran sulfate increases activity ISO RGD:1592081 6480464 Dextran Sulfate results in increased activity of MPO protein CTD PMID:15339030 more ... dextran sulfate multiple interactions ISO RGD:1592081 6480464 Capsaicin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; more ... CTD PMID:15573930 dextran sulfate multiple interactions ISO RGD:1592081 6480464 rosiglitazone inhibits the reaction [Dextran Sulfate results in increased expression of MPO protein] CTD PMID:21893696 dextran sulfate increases expression ISO RGD:1592081 6480464 Dextran Sulfate results in increased expression of MPO protein CTD PMID:21893696 dextran sulfate increases activity ISO RGD:1592081 6480464 Dextran Sulfate results in increased activity of MPO protein CTD PMID:15339030 PMID:16375993 dextran sulfate increases activity EXP   6480464 Dextran Sulfate results in increased activity of MPO protein CTD PMID:21724996 dextran sulfate multiple interactions EXP   6480464 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; more ... CTD PMID:21724996 dextran sulfate multiple interactions ISO RGD:1592081 6480464 zileuton inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein] CTD PMID:15339030 dextran sulfate increases activity ISO RGD:1592081 6480464 Dextran Sulfate results in increased activity of MPO protein CTD PMID:16375993 PMID:15339030 diarsenic trioxide multiple interactions ISO RGD:1346384 6480464 [Tretinoin co-treated with arsenic trioxide co-treated with hexamethylene bisacetamide] results in decreased expression of MPO mRNA; more ... CTD PMID:12130515 diarsenic trioxide multiple interactions ISO RGD:1346384 6480464 arsenic trioxide inhibits the reaction [Tretinoin results in decreased expression of MPO protein] CTD PMID:11133770 diarsenic trioxide decreases expression EXP   6480464 arsenic trioxide results in decreased expression of MPO protein CTD PMID:20693187 diazoxide increases activity ISO RGD:1592081 6480464 Isoproterenol results in increased activity of MPO protein CTD PMID:20693123 diazoxide multiple interactions ISO RGD:1592081 6480464 caffeic acid phenethyl ester inhibits the reaction [Isoproterenol results in increased activity of MPO protein] CTD PMID:20693123 dichloroacetic acid increases activity EXP   6480464 Dichloroacetic Acid results in increased activity of MPO protein CTD PMID:20391627 dimethyl sulfoxide increases secretion EXP   6480464 Dimethyl Sulfoxide results in increased secretion of MPO protein CTD PMID:21633126 diquat multiple interactions ISO RGD:1592081 6480464 Capsaicin inhibits the reaction [Diquat results in increased activity of MPO protein] CTD PMID:15046732 diquat increases activity ISO RGD:1592081 6480464 Diquat results in increased activity of MPO protein CTD PMID:15046732 docebenone multiple interactions EXP   6480464 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein] CTD PMID:7812673 domperidone multiple interactions EXP   6480464 Domperidone inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:21691039 donepezil hydrochloride multiple interactions EXP   6480464 donepezil inhibits the reaction [Streptozocin results in increased activity of MPO protein] CTD PMID:23060470 doxorubicin multiple interactions ISO RGD:1592081 6480464 caffeic acid phenethyl ester inhibits the reaction [Doxorubicin results in increased activity of MPO protein] CTD PMID:15369732 doxorubicin increases activity ISO RGD:1592081 6480464 Doxorubicin results in increased activity of MPO protein CTD PMID:14745846 more ... doxorubicin increases activity ISO RGD:1592081 6480464 Doxorubicin results in increased activity of MPO protein CTD PMID:14745846 more ... doxorubicin increases activity ISO RGD:1592081 6480464 Doxorubicin results in increased activity of MPO protein CTD PMID:14745846 more ... doxorubicin increases activity ISO RGD:1592081 6480464 Doxorubicin results in increased activity of MPO protein CTD PMID:15369732 more ... doxorubicin increases activity ISO RGD:1592081 6480464 Doxorubicin results in increased activity of MPO protein CTD PMID:14745846 more ... doxorubicin increases activity ISO RGD:1592081 6480464 Doxorubicin results in increased activity of MPO protein CTD PMID:15369732 more ... doxorubicin multiple interactions ISO RGD:1592081 6480464 Withanolides inhibits the reaction [Doxorubicin results in increased activity of MPO protein] CTD PMID:17520333 doxorubicin increases activity ISO RGD:1592081 6480464 Doxorubicin results in increased activity of MPO protein CTD PMID:15369732 more ... doxorubicin multiple interactions ISO RGD:1592081 6480464 Plant Extracts inhibits the reaction [Doxorubicin results in increased activity of MPO protein] CTD PMID:20146931 edaravone affects expression ISO RGD:1592081 6480464 phenylmethylpyrazolone affects the expression of MPO mRNA CTD PMID:18031376 edaravone decreases activity ISO RGD:1592081 6480464 phenylmethylpyrazolone results in decreased activity of MPO protein CTD PMID:14654979 edaravone multiple interactions ISO RGD:1592081 6480464 phenylmethylpyrazolone inhibits the reaction [Taurocholic Acid results in increased activity of MPO protein] CTD PMID:20035747 edaravone decreases expression ISO RGD:1592081 6480464 phenylmethylpyrazolone results in decreased expression of MPO protein CTD PMID:19694712 emodin multiple interactions ISO RGD:1592081 6480464 Emodin inhibits the reaction [1-Naphthylisothiocyanate results in increased activity of MPO protein] CTD PMID:18590720 ethanol multiple interactions ISO RGD:1592081 6480464 Capsaicin promotes the reaction [Ethanol results in increased activity of MPO protein]; more ... CTD PMID:15046732 ethanol increases activity ISO RGD:1592081 6480464 Ethanol results in increased activity of MPO protein CTD PMID:15046732 more ... ethanol multiple interactions ISO RGD:1592081 6480464 Drugs, Chinese Herbal inhibits the reaction [Ethanol results in increased activity of MPO protein]; more ... CTD PMID:22446813 ethanol increases secretion EXP   6480464 Ethanol results in increased secretion of MPO protein CTD PMID:21633126 ethanol increases activity ISO RGD:1592081 6480464 Ethanol results in increased activity of MPO protein CTD PMID:15046732 PMID:17603938 ethanol increases activity ISO RGD:1592081 6480464 Ethanol results in increased activity of MPO protein CTD PMID:17603938 PMID:15046732 ethanol multiple interactions ISO RGD:1592081 6480464 Acetylcysteine inhibits the reaction [Ethanol results in increased activity of MPO protein]; more ... CTD PMID:17603938 etoposide increases metabolic processing ISO RGD:1346384 6480464 MPO protein results in increased metabolism of Etoposide CTD PMID:16841962 eugenol multiple interactions ISO RGD:1592081 6480464 Eugenol inhibits the reaction [Thioacetamide results in increased activity of MPO protein] CTD PMID:20036707 famotidine multiple interactions ISO RGD:1592081 6480464 Famotidine inhibits the reaction [Ethanol results in increased activity of MPO protein] CTD PMID:17603938 famotidine multiple interactions ISO RGD:1592081 6480464 Famotidine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:19497431 more ... famotidine multiple interactions ISO RGD:1592081 6480464 Famotidine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:19034656 more ... famotidine multiple interactions ISO RGD:1592081 6480464 Famotidine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:19034656 more ... famotidine increases expression ISO RGD:1592081 6480464 Famotidine results in increased expression of MPO protein CTD PMID:12023551 famotidine decreases activity ISO RGD:1592081 6480464 Famotidine results in decreased activity of MPO protein CTD PMID:20723003 famotidine multiple interactions ISO RGD:1592081 6480464 Famotidine promotes the reaction [Chlorpheniramine results in decreased activity of MPO protein] CTD PMID:16437673 famotidine multiple interactions ISO RGD:1592081 6480464 Famotidine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:18726076 more ... famotidine multiple interactions EXP   6480464 Famotidine inhibits the reaction [Acids results in increased activity of MPO protein] CTD PMID:16091555 fenoterol multiple interactions ISO RGD:1346384 6480464 Ascorbic Acid inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Fenoterol]; more ... CTD PMID:19462961 ferroheme b multiple interactions ISO RGD:1592081 6480464 Heme inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:17292349 fluconazole increases expression ISO RGD:1592081 6480464 Fluconazole results in increased expression of MPO mRNA CTD PMID:20623750 fulvestrant multiple interactions ISO RGD:1592081 6480464 fulvestrant inhibits the reaction [resveratrol results in decreased activity of MPO protein] CTD PMID:21192278 gadolinium trichloride multiple interactions ISO RGD:1592081 6480464 gadolinium chloride inhibits the reaction [Thioacetamide results in increased activity of MPO protein] CTD PMID:12963478 gamma-hexachlorocyclohexane multiple interactions ISO RGD:1592081 6480464 [Lindane co-treated with Iron] results in increased activity of MPO protein CTD PMID:11141352 gamma-hexachlorocyclohexane multiple interactions ISO RGD:1592081 6480464 [Triiodothyronine co-treated with Lindane] results in increased activity of MPO protein CTD PMID:7503757 gamma-hexachlorocyclohexane increases activity ISO RGD:1592081 6480464 Lindane results in increased activity of MPO protein CTD PMID:11141352 glutathione multiple interactions ISO RGD:1346384 6480464 Glutathione inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Albuterol]; more ... CTD PMID:19462961 halothane decreases activity ISO RGD:1592081 6480464 Halothane results in decreased activity of MPO protein CTD PMID:15564938 hemin multiple interactions ISO RGD:1592081 6480464 Hemin inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein] CTD PMID:17979934 hyaluronic acid multiple interactions ISO RGD:1592081 6480464 [Chondroitin Sulfates co-treated with Hyaluronic Acid] inhibits the reaction [Carbon Tetrachloride results in increased activity of MPO protein] CTD PMID:14697411 hydrogen chloride increases activity ISO RGD:1592081 6480464 Hydrochloric Acid results in increased activity of MPO protein CTD PMID:15309881 PMID:11574821 hydrogen chloride increases activity ISO RGD:1592081 6480464 Hydrochloric Acid results in increased activity of MPO protein CTD PMID:11574821 PMID:15309881 hydrogen peroxide multiple interactions ISO RGD:1346384 6480464 [MPO protein co-treated with Hydrogen Peroxide] promotes the reaction [hydroquinone results in decreased activity of TOP2A protein] CTD PMID:15935818 hydrogen peroxide multiple interactions EXP   6480464 caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [MPO protein results in increased metabolism of Hydrogen Peroxide]] CTD PMID:22036979 hydrogen peroxide increases metabolic processing EXP   6480464 MPO protein results in increased metabolism of Hydrogen Peroxide CTD PMID:22036979 hydrogen peroxide multiple interactions ISO RGD:1346384 6480464 [MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 2,4-dichloroaniline; more ... CTD PMID:20199096 hydrogen peroxide multiple interactions ISO RGD:1346384 6480464 Ascorbic Acid inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Fenoterol]; more ... CTD PMID:19462961 hydrogen peroxide multiple interactions ISO RGD:1346384 6480464 [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of nimesulide metabolite] which results in increased chemical synthesis of nimesulide metabolite; more ... CTD PMID:20939553 hydroquinone multiple interactions ISO RGD:1346384 6480464 MPO protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein] CTD PMID:15777082 hydroquinone increases oxidation ISO RGD:1346384 6480464 MPO protein results in increased oxidation of hydroquinone CTD PMID:10994872 hydroquinone multiple interactions ISO RGD:1346384 6480464 [MPO protein co-treated with Hydrogen Peroxide] promotes the reaction [hydroquinone results in decreased activity of TOP2A protein] CTD PMID:15935818 hypochlorous acid multiple interactions ISO RGD:1346384 6480464 [MPO protein co-treated with Hypochlorous Acid] results in increased oxidation of and affects the activity of nimesulide metabolite; more ... CTD PMID:20939553 indole-3-butyric acid increases activity ISO RGD:1592081 6480464 indolebutyric acid results in increased activity of MPO protein CTD PMID:19442822 indomethacin multiple interactions EXP   6480464 Domperidone inhibits the reaction [Indomethacin results in increased activity of MPO protein]; more ... CTD PMID:21691039 indomethacin increases activity EXP   6480464 Indomethacin results in increased activity of MPO protein CTD PMID:10567023 more ... indomethacin increases activity ISO RGD:1592081 6480464 Indomethacin results in increased activity of MPO protein CTD PMID:10210152 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 Famotidine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:18726076 more ... indomethacin increases activity ISO RGD:1592081 6480464 Indomethacin results in increased activity of MPO protein CTD PMID:17002672 more ... indomethacin increases expression ISO RGD:1592081 6480464 Indomethacin results in increased expression of MPO protein CTD PMID:12024109 PMID:16080005 indomethacin multiple interactions ISO RGD:1592081 6480464 Ranitidine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:16169175 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 pantoprazole inhibits the reaction [Indomethacin results in increased expression of MPO protein] CTD PMID:16080005 indomethacin multiple interactions ISO RGD:1592081 6480464 lansoprazole inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:18726076 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 Ampicillin inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11991626 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 16,16-Dimethylprostaglandin E2 inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11686837 more ... indomethacin increases activity EXP   6480464 Indomethacin results in increased activity of MPO protein CTD PMID:10567023 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 16,16-Dimethylprostaglandin E2 inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11686837 more ... indomethacin increases activity EXP   6480464 Indomethacin results in increased activity of MPO protein CTD PMID:21691039 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 Ranitidine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:18726076 more ... indomethacin increases activity ISO RGD:1592081 6480464 Indomethacin results in increased activity of MPO protein CTD PMID:16113693 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 lansoprazole inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17895592 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 lansoprazole inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17151854 more ... indomethacin increases expression ISO RGD:1592081 6480464 Indomethacin results in increased expression of MPO protein CTD PMID:12024109 indomethacin increases activity ISO RGD:1592081 6480464 Indomethacin results in increased activity of MPO protein CTD PMID:16133968 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 Indomethacin inhibits the reaction [Capsaicin affects the activity of MPO protein]; more ... CTD PMID:12893632 indomethacin multiple interactions ISO RGD:1592081 6480464 Famotidine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:19497431 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 16,16-Dimethylprostaglandin E2 inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11855677 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 Ampicillin inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11686837 more ... indomethacin increases activity EXP   6480464 Indomethacin results in increased activity of MPO protein CTD PMID:10567023 more ... indomethacin increases activity ISO RGD:1592081 6480464 Indomethacin results in increased activity of MPO protein CTD PMID:16133968 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 Famotidine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:19034656 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 16,16-Dimethylprostaglandin E2 inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11991626 more ... indomethacin increases activity EXP   6480464 Indomethacin results in increased activity of MPO protein CTD PMID:21691039 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 Ranitidine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:16169175 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 lansoprazole inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:18726076 more ... indomethacin increases activity ISO RGD:1592081 6480464 Indomethacin results in increased activity of MPO protein CTD PMID:19034656 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 Ampicillin inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11686837 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 16,16-Dimethylprostaglandin E2 inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11991626 more ... indomethacin increases activity EXP   6480464 Indomethacin results in increased activity of MPO protein CTD PMID:10567023 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 usnic acid inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:16169175 indomethacin multiple interactions ISO RGD:1592081 6480464 tianeptine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:19497431 indomethacin multiple interactions ISO RGD:1592081 6480464 thiaton inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11855677 indomethacin multiple interactions ISO RGD:1592081 6480464 Tacrolimus inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17202747 indomethacin multiple interactions ISO RGD:1592081 6480464 sildenafil inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:16113693 indomethacin multiple interactions ISO RGD:1592081 6480464 Rolipram inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:14567935 indomethacin multiple interactions ISO RGD:1592081 6480464 rebamipide inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11686837 indomethacin multiple interactions ISO RGD:1592081 6480464 Ranitidine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17895592 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 Pentoxifylline inhibits the reaction [Indomethacin results in increased activity of MPO protein]; more ... CTD PMID:16133968 indomethacin multiple interactions ISO RGD:1592081 6480464 ONO-AE1-329 inhibits the reaction [Indomethacin results in increased activity of MPO protein]; more ... CTD PMID:11991626 indomethacin multiple interactions ISO RGD:1592081 6480464 Omeprazole inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17151854 indomethacin multiple interactions ISO RGD:1592081 6480464 montelukast inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17895592 indomethacin multiple interactions ISO RGD:1592081 6480464 lansoprazole inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17895592 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 mirtazapine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:19034656 indomethacin multiple interactions ISO RGD:1592081 6480464 irsogladine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:18306037 indomethacin increases activity ISO RGD:1592081 6480464 Indomethacin results in increased activity of MPO protein CTD PMID:19497431 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 Indomethacin inhibits the reaction [NPPA protein affects the activity of MPO protein] CTD PMID:17522345 indomethacin multiple interactions ISO RGD:1592081 6480464 fucoidan inhibits the reaction [Indomethacin results in increased activity of MPO protein]; more ... CTD PMID:18209962 indomethacin multiple interactions ISO RGD:1592081 6480464 Famotidine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:19034656 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 Curcumin inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17351913 indomethacin multiple interactions ISO RGD:1592081 6480464 Capsaicin inhibits the reaction [Indomethacin results in increased activity of MPO protein]; more ... CTD PMID:10671773 indomethacin multiple interactions ISO RGD:1592081 6480464 candesartan inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17763956 indomethacin multiple interactions ISO RGD:1592081 6480464 bis(2-guanidinoethyl)disulfide inhibits the reaction [Indomethacin results in increased activity of MPO protein]; more ... CTD PMID:11713966 indomethacin multiple interactions ISO RGD:1592081 6480464 Ascorbic Acid inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:18726076 indomethacin multiple interactions ISO RGD:1592081 6480464 Ampicillin inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:18306037 more ... indomethacin multiple interactions ISO RGD:1592081 6480464 Amiodarone promotes the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:18087811 indomethacin multiple interactions ISO RGD:1592081 6480464 Allopurinol inhibits the reaction [Indomethacin results in increased activity of MPO protein]; more ... CTD PMID:12566098 indomethacin multiple interactions ISO RGD:1592081 6480464 16,16-Dimethylprostaglandin E2 inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11855677 more ... indomethacin multiple interactions EXP   6480464 rebamipide inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:16184426 indomethacin increases activity EXP   6480464 Indomethacin results in increased activity of MPO protein CTD PMID:21691039 more ... indomethacin multiple interactions EXP   6480464 Indomethacin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein] CTD PMID:16716910 indomethacin multiple interactions EXP   6480464 (glycyl-glycyl)GLP-2 inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:10567023 indomethacin multiple interactions EXP   6480464 Dexamethasone inhibits the reaction [Indomethacin results in increased activity of MPO protein]; more ... CTD PMID:15138204 iron atom multiple interactions ISO RGD:1592081 6480464 [Lindane co-treated with Iron] results in increased activity of MPO protein CTD PMID:11141352 iron atom increases activity ISO RGD:1592081 6480464 Iron results in increased activity of MPO protein CTD PMID:11141352 isoflurane decreases activity ISO RGD:1592081 6480464 Isoflurane results in decreased activity of MPO protein CTD PMID:15564938 isoorientin multiple interactions ISO RGD:1592081 6480464 homoorientin inhibits the reaction [Ethanol results in increased activity of MPO protein] CTD PMID:22446813 isoprenaline multiple interactions ISO RGD:1592081 6480464 caffeic acid phenethyl ester inhibits the reaction [Isoproterenol results in increased activity of MPO protein] CTD PMID:20693123 isoprenaline increases activity ISO RGD:1592081 6480464 Isoproterenol results in increased activity of MPO protein CTD PMID:20693123 ketoprofen multiple interactions ISO RGD:1592081 6480464 pantoprazole inhibits the reaction [Ketoprofen results in increased expression of MPO protein] CTD PMID:16080005 ketoprofen increases expression ISO RGD:1592081 6480464 Ketoprofen results in increased expression of MPO protein CTD PMID:16080005 L-ascorbic acid multiple interactions ISO RGD:1346384 6480464 Ascorbic Acid inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Fenoterol]; more ... CTD PMID:19462961 L-ascorbic acid multiple interactions ISO RGD:1592081 6480464 Ascorbic Acid inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:18726076 lansoprazole multiple interactions ISO RGD:1592081 6480464 lansoprazole inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17895592 more ... lansoprazole multiple interactions ISO RGD:1592081 6480464 lansoprazole inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17151854 more ... lansoprazole multiple interactions ISO RGD:1592081 6480464 lansoprazole inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:18726076 more ... lansoprazole multiple interactions ISO RGD:1592081 6480464 lansoprazole inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17151854 more ... lisinopril dihydrate multiple interactions EXP   6480464 Lisinopril inhibits the reaction [Streptozocin results in increased activity of MPO protein]; more ... CTD PMID:23060470 mercury atom decreases activity ISO RGD:1346384 6480464 Mercury results in decreased activity of MPO protein CTD PMID:15557676 mercury(0) decreases activity ISO RGD:1346384 6480464 Mercury results in decreased activity of MPO protein CTD PMID:15557676 methimazole multiple interactions ISO RGD:1592081 6480464 Methimazole inhibits the reaction [Thioacetamide results in increased activity of MPO protein] CTD PMID:22564261 methotrexate increases activity ISO RGD:1592081 6480464 Methotrexate results in increased activity of MPO protein CTD PMID:20816014 methotrexate increases expression ISO RGD:1592081 6480464 Methotrexate results in increased expression of MPO protein CTD PMID:20885979 methotrexate multiple interactions ISO RGD:1592081 6480464 Curcumin inhibits the reaction [Methotrexate results in increased expression of MPO protein]; more ... CTD PMID:20885979 metoclopramide multiple interactions EXP   6480464 Metoclopramide inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:21691039 mirtazapine multiple interactions ISO RGD:1592081 6480464 mirtazapine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:19034656 mono(2-ethylhexyl) phthalate increases expression EXP   6480464 mono-(2-ethylhexyl)phthalate results in increased expression of MPO mRNA CTD PMID:22401849 montelukast multiple interactions ISO RGD:1592081 6480464 montelukast inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17895592 montelukast multiple interactions ISO RGD:1592081 6480464 montelukast inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:11698051 N,N-dimethylformamide increases expression ISO RGD:1346384 6480464 Dimethylformamide results in increased expression of MPO mRNA CTD PMID:18063697 N-acetyl-L-cysteine multiple interactions ISO RGD:1592081 6480464 Acetylcysteine inhibits the reaction [Ethanol results in increased activity of MPO protein] CTD PMID:17603938 N-acetyl-L-cysteine multiple interactions ISO RGD:1592081 6480464 Acetylcysteine inhibits the reaction [Smoke results in increased activity of MPO protein] CTD PMID:22664789 N-acetyl-L-cysteine multiple interactions ISO RGD:1346384 6480464 [MPO protein co-treated with XDH protein co-treated with Acetaldehyde] promotes the reaction [Serotonin binds to Acetylcysteine] CTD PMID:23009681 N-acetyl-L-cysteine multiple interactions ISO RGD:1592081 6480464 Acetylcysteine inhibits the reaction [Methotrexate results in increased expression of MPO protein] CTD PMID:20885979 N-acetyl-L-cysteine multiple interactions ISO RGD:1592081 6480464 Acetylcysteine inhibits the reaction [Gentamicins results in increased activity of MPO protein] CTD PMID:11470263 N-formyl-L-methionyl-L-leucyl-L-phenylalanine multiple interactions EXP   6480464 carvedilol inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of MPO protein] CTD PMID:17159805 N-formyl-L-methionyl-L-leucyl-L-phenylalanine multiple interactions ISO RGD:1346384 6480464 carvedilol inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased secretion of MPO protein] CTD PMID:18987595 PMID:16601795 N-formyl-L-methionyl-L-leucyl-L-phenylalanine increases secretion ISO RGD:1346384 6480464 N-Formylmethionine Leucyl-Phenylalanine results in increased secretion of MPO protein CTD PMID:16601795 PMID:18987595 N-formyl-L-methionyl-L-leucyl-L-phenylalanine multiple interactions ISO RGD:1346384 6480464 wortmannin inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased secretion of MPO protein] CTD PMID:18987595 N-formyl-L-methionyl-L-leucyl-L-phenylalanine increases secretion ISO RGD:1346384 6480464 N-Formylmethionine Leucyl-Phenylalanine results in increased secretion of MPO protein CTD PMID:18987595 PMID:16601795 N-formyl-L-methionyl-L-leucyl-L-phenylalanine multiple interactions ISO RGD:1346384 6480464 carvedilol inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased secretion of MPO protein] CTD PMID:16601795 PMID:18987595 N-formyl-L-methionyl-L-leucyl-L-phenylalanine increases expression EXP   6480464 N-Formylmethionine Leucyl-Phenylalanine results in increased expression of MPO protein CTD PMID:17159805 nickel sulfate decreases expression ISO RGD:1346384 6480464 nickel sulfate results in decreased expression of MPO mRNA CTD PMID:17374397 nimesulide decreases activity ISO RGD:1592081 6480464 nimesulide results in decreased activity of MPO CTD PMID:11996850 nimesulide multiple interactions ISO RGD:1346384 6480464 [MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of and affects the activity of nimesulide metabolite; more ... CTD PMID:20939553 nitric oxide increases expression ISO RGD:1592081 6480464 Nitric Oxide results in increased expression of MPO protein CTD PMID:10706834 nitric oxide multiple interactions ISO RGD:1592081 6480464 [Paraquat co-treated with Nitric Oxide] results in increased activity of MPO protein CTD PMID:15820443 nitroglycerin decreases activity ISO RGD:1592081 6480464 Nitroglycerin results in decreased activity of MPO protein CTD PMID:8869312 o-toluidine multiple interactions ISO RGD:1346384 6480464 [MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 2-toluidine; more ... CTD PMID:20199096 omeprazole multiple interactions EXP   6480464 Omeprazole inhibits the reaction [Acids results in increased activity of MPO protein] CTD PMID:16091555 omeprazole multiple interactions ISO RGD:1592081 6480464 Omeprazole inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17151854 omeprazole multiple interactions ISO RGD:1592081 6480464 Omeprazole inhibits the reaction [Cysteamine results in increased expression of MPO protein] CTD PMID:20165931 p-toluidine multiple interactions ISO RGD:1346384 6480464 [[MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 4-toluidine] which results in increased expression of MPO protein modified form CTD PMID:20199096 pantoprazole multiple interactions ISO RGD:1592081 6480464 pantoprazole inhibits the reaction [Ketoprofen results in increased expression of MPO protein]; more ... CTD PMID:16080005 paracetamol increases activity EXP   6480464 Acetaminophen results in increased activity of MPO protein CTD PMID:20720158 paracetamol increases activity ISO RGD:1592081 6480464 Acetaminophen results in increased activity of MPO protein CTD PMID:18597074 paracetamol multiple interactions ISO RGD:1592081 6480464 Acetaminophen promotes the reaction [Carnitine deficiency results in increased activity of MPO protein] CTD PMID:18597074 paracetamol increases expression EXP   6480464 Acetaminophen results in increased expression of MPO protein CTD PMID:20933533 paracetamol increases expression EXP   6480464 Acetaminophen results in increased expression of MPO mRNA CTD PMID:18544908 paraquat multiple interactions ISO RGD:1592081 6480464 [Paraquat co-treated with Nitric Oxide] results in increased activity of MPO protein CTD PMID:15820443 paraquat increases activity ISO RGD:1592081 6480464 Paraquat results in increased activity of MPO protein CTD PMID:15820443 more ... paraquat multiple interactions ISO RGD:1592081 6480464 Ambroxol inhibits the reaction [Paraquat results in increased activity of MPO protein] CTD PMID:21921364 paraquat increases activity ISO RGD:1592081 6480464 Paraquat results in increased activity of MPO protein CTD PMID:17015168 PMID:15820443 paraquat increases activity ISO RGD:1592081 6480464 Paraquat results in increased activity of MPO protein CTD PMID:15820443 PMID:17015168 paraquat multiple interactions ISO RGD:1592081 6480464 Dexamethasone inhibits the reaction [Paraquat results in increased activity of MPO protein]; more ... CTD PMID:17015168 pentobarbital increases activity ISO RGD:1592081 6480464 Pentobarbital results in increased activity of MPO protein CTD PMID:15564938 perfluorooctanoic acid increases expression EXP   6480464 perfluorooctanoic acid results in increased expression of MPO mRNA CTD PMID:20118188 perfluorooctanoic acid multiple interactions EXP   6480464 PPARA promotes the reaction [perfluorooctanoic acid results in decreased expression of MPO mRNA] CTD PMID:20118188 permethrin increases activity ISO RGD:1592081 6480464 Permethrin results in increased activity of MPO protein CTD PMID:19772857 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:1346384 6480464 CMI 392 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein] CTD PMID:11529688 phorbol 13-acetate 12-myristate increases expression EXP   6480464 Tetradecanoylphorbol Acetate results in increased expression of MPO CTD PMID:10381133 phorbol 13-acetate 12-myristate multiple interactions EXP   6480464 resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO] CTD PMID:10381133 phorbol 13-acetate 12-myristate increases activity EXP   6480464 Tetradecanoylphorbol Acetate results in increased activity of MPO protein CTD PMID:16716910 more ... phorbol 13-acetate 12-myristate multiple interactions EXP   6480464 caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; more ... CTD PMID:22036979 phorbol 13-acetate 12-myristate increases activity EXP   6480464 Tetradecanoylphorbol Acetate results in increased activity of MPO protein CTD PMID:16716910 more ... phorbol 13-acetate 12-myristate multiple interactions ISO RGD:1346384 6480464 carvedilol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MPO protein] CTD PMID:16601795 PMID:18987595 phorbol 13-acetate 12-myristate increases activity EXP   6480464 Tetradecanoylphorbol Acetate results in increased activity of MPO protein CTD PMID:8273558 more ... phorbol 13-acetate 12-myristate increases secretion ISO RGD:1346384 6480464 Tetradecanoylphorbol Acetate results in increased secretion of MPO protein CTD PMID:18987595 PMID:16601795 phorbol 13-acetate 12-myristate increases activity EXP   6480464 Tetradecanoylphorbol Acetate results in increased activity of MPO protein CTD PMID:8273558 more ... phorbol 13-acetate 12-myristate increases secretion ISO RGD:1346384 6480464 Tetradecanoylphorbol Acetate results in increased secretion of MPO protein CTD PMID:16601795 PMID:18987595 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:1346384 6480464 carvedilol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MPO protein] CTD PMID:18987595 PMID:16601795 phorbol 13-acetate 12-myristate increases activity EXP   6480464 Tetradecanoylphorbol Acetate results in increased activity of MPO protein CTD PMID:8273558 more ... phorbol 13-acetate 12-myristate increases activity EXP   6480464 Tetradecanoylphorbol Acetate results in increased activity of MPO protein CTD PMID:8273558 more ... phorbol 13-acetate 12-myristate increases activity ISO RGD:1346384 6480464 Tetradecanoylphorbol Acetate results in increased activity of MPO protein CTD PMID:3030588 PMID:11529688 phorbol 13-acetate 12-myristate increases activity EXP   6480464 Tetradecanoylphorbol Acetate results in increased activity of MPO protein CTD PMID:8113982 more ... phorbol 13-acetate 12-myristate multiple interactions EXP   6480464 scalaradial inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein] CTD PMID:8113982 phorbol 13-acetate 12-myristate multiple interactions EXP   6480464 Indomethacin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; more ... CTD PMID:16716910 phorbol 13-acetate 12-myristate multiple interactions EXP   6480464 bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein] CTD PMID:8273558 phorbol 13-acetate 12-myristate multiple interactions EXP   6480464 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; more ... CTD PMID:7812673 phorbol 13-acetate 12-myristate increases activity ISO RGD:1346384 6480464 Tetradecanoylphorbol Acetate results in increased activity of MPO protein CTD PMID:11529688 PMID:3030588 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:1346384 6480464 Potassium Cyanide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; more ... CTD PMID:3030588 pirinixic acid multiple interactions EXP   6480464 pirinixic acid inhibits the reaction [Bleomycin results in increased activity of MPO protein] CTD PMID:16317386 pirinixic acid decreases activity ISO RGD:1592081 6480464 pirinixic acid results in decreased activity of MPO protein CTD PMID:19058328 piroxicam decreases activity ISO RGD:1592081 6480464 Piroxicam results in decreased activity of MPO CTD PMID:11996850 piroxicam increases expression ISO RGD:1592081 6480464 Piroxicam results in increased expression of MPO protein CTD PMID:16080005 piroxicam multiple interactions ISO RGD:1592081 6480464 pantoprazole inhibits the reaction [Piroxicam results in increased expression of MPO protein] CTD PMID:16080005 piroxicam increases activity ISO RGD:1592081 6480464 Piroxicam results in increased activity of MPO protein CTD PMID:15309881 potassium cyanide multiple interactions ISO RGD:1346384 6480464 Potassium Cyanide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein] CTD PMID:3030588 prednisolone multiple interactions EXP   6480464 Prednisolone inhibits the reaction [Picryl Chloride results in increased activity of MPO protein] CTD PMID:16442096 prednisolone multiple interactions ISO RGD:1592081 6480464 Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:22119283 procainamide multiple interactions ISO RGD:1346384 6480464 [MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of Procainamide; more ... CTD PMID:20199096 prostaglandin E2 multiple interactions ISO RGD:1592081 6480464 Dinoprostone analog inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:22039321 pyridaben increases expression EXP   6480464 pyridaben results in increased expression of MPO mRNA CTD PMID:22563483 raloxifene multiple interactions ISO RGD:1592081 6480464 Carrageenan inhibits the reaction [Raloxifene results in increased activity of MPO protein] CTD PMID:15860553 ranitidine decreases expression ISO RGD:1592081 6480464 Ranitidine results in decreased expression of MPO protein CTD PMID:12023551 ranitidine multiple interactions ISO RGD:1592081 6480464 Ranitidine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:16169175 more ... ranitidine multiple interactions ISO RGD:1592081 6480464 Ranitidine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17895592 more ... ranitidine multiple interactions ISO RGD:1592081 6480464 Ranitidine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:16169175 more ... ranitidine multiple interactions ISO RGD:1592081 6480464 Ranitidine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17895592 more ... ranitidine multiple interactions ISO RGD:1592081 6480464 Ranitidine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:18726076 more ... resveratrol decreases activity ISO RGD:1592081 6480464 resveratrol results in decreased activity of MPO protein CTD PMID:15637762 more ... resveratrol decreases activity ISO RGD:1592081 6480464 resveratrol results in decreased activity of MPO protein CTD PMID:15637762 PMID:21192278 resveratrol multiple interactions ISO RGD:1592081 6480464 resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:16474422 PMID:22029500 resveratrol decreases expression ISO RGD:1592081 6480464 resveratrol results in decreased expression of MPO protein CTD PMID:21111721 resveratrol multiple interactions ISO RGD:1592081 6480464 resveratrol inhibits the reaction [Bleomycin results in increased activity of MPO protein] CTD PMID:17035056 resveratrol multiple interactions ISO RGD:1592081 6480464 chromium mesoporphyrin inhibits the reaction [resveratrol results in decreased activity of MPO protein]; more ... CTD PMID:21192278 resveratrol increases activity EXP   6480464 resveratrol results in increased activity of MPO protein CTD PMID:19066340 resveratrol multiple interactions EXP   6480464 resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO] CTD PMID:10381133 resveratrol multiple interactions EXP   6480464 resveratrol inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein] CTD PMID:20637373 resveratrol decreases activity EXP   6480464 resveratrol analog results in decreased activity of MPO protein CTD PMID:19066340 resveratrol multiple interactions ISO RGD:1592081 6480464 resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:16474422 resveratrol decreases activity ISO RGD:1592081 6480464 resveratrol results in decreased activity of MPO protein CTD PMID:15637762 resveratrol multiple interactions ISO RGD:1592081 6480464 resveratrol inhibits the reaction [lipopolysaccharide, Escherichia coli 0111 B4 results in increased expression of MPO protein] CTD PMID:15734790 resveratrol increases activity EXP   6480464 resveratrol results in increased activity of MPO protein CTD PMID:19066340 PMID:20067468 rolipram multiple interactions EXP   6480464 Rolipram inhibits the reaction [Picryl Chloride results in increased activity of MPO protein] CTD PMID:16442096 rolipram multiple interactions ISO RGD:1592081 6480464 Rolipram inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:14567935 rolipram multiple interactions ISO RGD:1592081 6480464 Rolipram inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein] CTD PMID:18710439 rosiglitazone multiple interactions EXP   6480464 rosiglitazone inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein] CTD PMID:19778788 rosiglitazone multiple interactions ISO RGD:1592081 6480464 rosiglitazone inhibits the reaction [Dextran Sulfate results in increased expression of MPO protein] CTD PMID:21893696 rosiglitazone multiple interactions ISO RGD:1592081 6480464 2-chloro-5-nitrobenzanilide inhibits the reaction [rosiglitazone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of MPO protein]] CTD PMID:16215386 serotonin multiple interactions ISO RGD:1346384 6480464 [MPO protein co-treated with XDH protein co-treated with Acetaldehyde] promotes the reaction [Serotonin binds to Acetylcysteine]; more ... CTD PMID:23009681 sevoflurane decreases activity ISO RGD:1592081 6480464 sevoflurane results in decreased activity of MPO protein CTD PMID:15564938 sildenafil multiple interactions ISO RGD:1592081 6480464 sildenafil inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:16113693 silicon dioxide increases activity EXP   6480464 Silicon Dioxide results in increased activity of MPO protein CTD PMID:20421647 silicon dioxide multiple interactions EXP   6480464 IL17R protein affects the reaction [Silicon Dioxide results in increased activity of MPO protein] CTD PMID:20421647 silver atom decreases expression EXP   6480464 Silver results in decreased expression of MPO mRNA CTD PMID:19429238 silver(0) decreases expression EXP   6480464 Silver results in decreased expression of MPO mRNA CTD PMID:19429238 simvastatin multiple interactions ISO RGD:1346384 6480464 Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of MPO protein] CTD PMID:17038636 simvastatin decreases activity ISO RGD:1592081 6480464 Simvastatin results in decreased activity of MPO protein CTD PMID:21764683 simvastatin multiple interactions EXP   6480464 Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein] CTD PMID:15665042 simvastatin decreases expression ISO RGD:1346384 6480464 Simvastatin results in decreased expression of MPO protein CTD PMID:17038636 sodium azide multiple interactions ISO RGD:1346384 6480464 Sodium Azide inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Albuterol]; more ... CTD PMID:19462961 sodium cyanide multiple interactions ISO RGD:1346384 6480464 Sodium Cyanide inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Fenoterol]; more ... CTD PMID:19462961 streptozocin multiple interactions EXP   6480464 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Lisinopril inhibits the reaction [Streptozocin results in increased activity of MPO protein]]; more ... CTD PMID:23060470 streptozocin increases activity EXP   6480464 Streptozocin results in increased activity of MPO protein CTD PMID:23060470 sulfasalazine multiple interactions ISO RGD:1592081 6480464 Sulfasalazine inhibits the reaction [Dinitrochlorobenzene results in decreased activity of MPO protein] CTD PMID:17373747 sulfasalazine multiple interactions ISO RGD:1592081 6480464 Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:22119283 sulfasalazine decreases activity ISO RGD:1592081 6480464 Sulfasalazine results in decreased activity of MPO protein CTD PMID:20380826 tacrolimus hydrate multiple interactions ISO RGD:1592081 6480464 Tacrolimus inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:17202747 tacrolimus hydrate decreases expression ISO RGD:1592081 6480464 Tacrolimus results in decreased expression of MPO protein CTD PMID:9655420 taurine multiple interactions ISO RGD:1592081 6480464 Taurine inhibits the reaction [Alloxan results in increased activity of MPO protein] CTD PMID:22138235 taurocholic acid multiple interactions ISO RGD:1592081 6480464 phenylmethylpyrazolone inhibits the reaction [Taurocholic Acid results in increased activity of MPO protein] CTD PMID:20035747 taurocholic acid increases expression ISO RGD:1592081 6480464 Taurocholic Acid results in increased expression of MPO protein CTD PMID:16440434 taurocholic acid increases activity ISO RGD:1592081 6480464 Taurocholic Acid results in increased activity of MPO protein CTD PMID:20035747 telmisartan multiple interactions EXP   6480464 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [telmisartan inhibits the reaction [Streptozocin results in increased activity of MPO protein]] CTD PMID:23060470 terbutaline multiple interactions ISO RGD:1346384 6480464 [MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Terbutaline CTD PMID:19462961 tetrachloromethane increases activity ISO RGD:1592081 6480464 Carbon Tetrachloride results in increased activity of MPO protein CTD PMID:14697411 more ... tetrachloromethane multiple interactions ISO RGD:1592081 6480464 IGF1 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of MPO protein] CTD PMID:15745444 tetrachloromethane increases expression ISO RGD:1592081 6480464 Carbon Tetrachloride results in increased expression of MPO protein CTD PMID:15745444 tetrachloromethane increases activity ISO RGD:1592081 6480464 Carbon Tetrachloride results in increased activity of MPO protein CTD PMID:14697411 more ... tetrachloromethane increases activity ISO RGD:1592081 6480464 Carbon Tetrachloride results in increased activity of MPO protein CTD PMID:16278809 more ... tetrachloromethane multiple interactions ISO RGD:1592081 6480464 [Chondroitin Sulfates co-treated with Hyaluronic Acid] inhibits the reaction [Carbon Tetrachloride results in increased activity of MPO protein] CTD PMID:14697411 thalidomide multiple interactions EXP   6480464 Thalidomide inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:15138204 theophylline decreases expression ISO RGD:1346384 6480464 Theophylline results in decreased expression of MPO protein CTD PMID:12016098 theophylline multiple interactions ISO RGD:1592081 6480464 Theophylline inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:16133968 thiabendazole increases metabolic processing ISO RGD:1346384 6480464 MPO protein results in increased metabolism of Thiabendazole metabolite CTD PMID:21513789 thioacetamide increases activity ISO RGD:1592081 6480464 Thioacetamide results in increased activity of MPO protein CTD PMID:16724977 PMID:12963478 thioacetamide multiple interactions ISO RGD:1592081 6480464 Methimazole inhibits the reaction [Thioacetamide results in increased activity of MPO protein] CTD PMID:22564261 thioacetamide increases activity ISO RGD:1592081 6480464 Thioacetamide results in increased activity of MPO protein CTD PMID:12963478 more ... thioacetamide increases activity ISO RGD:1592081 6480464 Thioacetamide results in increased activity of MPO protein CTD PMID:12963478 more ... thioacetamide increases activity ISO RGD:1592081 6480464 Thioacetamide results in increased activity of MPO protein CTD PMID:12963478 more ... thioacetamide increases activity ISO RGD:1592081 6480464 Thioacetamide results in increased activity of MPO protein CTD PMID:16724977 more ... thioacetamide multiple interactions ISO RGD:1592081 6480464 Eugenol inhibits the reaction [Thioacetamide results in increased activity of MPO protein] CTD PMID:20036707 thioacetamide increases activity ISO RGD:1592081 6480464 Thioacetamide results in increased activity of MPO protein CTD PMID:12963478 PMID:16724977 thioacetamide multiple interactions ISO RGD:1592081 6480464 gadolinium chloride inhibits the reaction [Thioacetamide results in increased activity of MPO protein] CTD PMID:12963478 trans-resveratrol decreases activity ISO RGD:1592081 6480464 resveratrol results in decreased activity of MPO protein CTD PMID:15637762 more ... trans-resveratrol decreases activity ISO RGD:1592081 6480464 resveratrol results in decreased activity of MPO protein CTD PMID:15637762 PMID:21192278 trans-resveratrol multiple interactions ISO RGD:1592081 6480464 resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:16474422 PMID:22029500 trans-resveratrol decreases expression ISO RGD:1592081 6480464 resveratrol results in decreased expression of MPO protein CTD PMID:21111721 trans-resveratrol multiple interactions ISO RGD:1592081 6480464 resveratrol inhibits the reaction [Bleomycin results in increased activity of MPO protein] CTD PMID:17035056 trans-resveratrol multiple interactions ISO RGD:1592081 6480464 chromium mesoporphyrin inhibits the reaction [resveratrol results in decreased activity of MPO protein]; more ... CTD PMID:21192278 trans-resveratrol increases activity EXP   6480464 resveratrol results in increased activity of MPO protein CTD PMID:19066340 trans-resveratrol multiple interactions EXP   6480464 resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO] CTD PMID:10381133 trans-resveratrol multiple interactions EXP   6480464 resveratrol inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein] CTD PMID:20637373 trans-resveratrol decreases activity EXP   6480464 resveratrol analog results in decreased activity of MPO protein CTD PMID:19066340 trans-resveratrol increases activity EXP   6480464 resveratrol results in increased activity of MPO protein CTD PMID:19066340 PMID:20067468 trans-resveratrol multiple interactions ISO RGD:1592081 6480464 resveratrol inhibits the reaction [lipopolysaccharide, Escherichia coli 0111 B4 results in increased expression of MPO protein] CTD PMID:15734790 trans-resveratrol decreases activity ISO RGD:1592081 6480464 resveratrol results in decreased activity of MPO protein CTD PMID:15637762 trans-resveratrol multiple interactions ISO RGD:1592081 6480464 resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:16474422 trichloroacetic acid increases activity EXP   6480464 Trichloroacetic Acid results in increased activity of MPO protein CTD PMID:20391627 trichostatin A multiple interactions ISO RGD:1346384 6480464 [decitabine co-treated with trichostatin A] results in increased expression of MPO mRNA CTD PMID:17185465 troglitazone decreases activity EXP   6480464 troglitazone results in decreased activity of MPO protein CTD PMID:12468449 urethane multiple interactions EXP   6480464 [Urethane co-treated with Chloralose] inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein] CTD PMID:16867022 ursodeoxycholic acid decreases activity EXP   6480464 Ursodeoxycholic Acid results in decreased activity of MPO protein CTD PMID:17888421 usnic acid multiple interactions ISO RGD:1592081 6480464 usnic acid inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:16169175 valproic acid affects expression EXP   6480464 Valproic Acid affects the expression of MPO mRNA CTD PMID:17963808 verapamil multiple interactions ISO RGD:1592081 6480464 Verapamil promotes the reaction [Paraquat results in increased activity of MPO protein] CTD PMID:17015168 wortmannin multiple interactions ISO RGD:1346384 6480464 wortmannin inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased secretion of MPO protein] CTD PMID:18987595 zafirlukast decreases activity ISO RGD:1592081 6480464 zafirlukast results in decreased activity of MPO protein CTD PMID:11438310 zafirlukast decreases expression ISO RGD:1592081 6480464 zafirlukast results in decreased expression of MPO protein CTD PMID:12962976 zinc atom multiple interactions ISO RGD:1592081 6480464 Zinc inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:12566098 zinc atom increases activity ISO RGD:1592081 6480464 Zinc deficiency results in increased activity of MPO protein CTD PMID:10938463 zinc protoporphyrin multiple interactions ISO RGD:1592081 6480464 zinc protoporphyrin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:17292349 zinc(0) multiple interactions ISO RGD:1592081 6480464 Zinc inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:12566098 zinc(0) increases activity ISO RGD:1592081 6480464 Zinc deficiency results in increased activity of MPO protein CTD PMID:10938463 Gene Ontology Annotations Biological Process Term Qualifier Evidence With Reference Notes Source Original Reference(s) defense response to fungus   IMP MGI:MGI:2176344 2290270 MGI:MGI:1333719|PMID:10085024 MGI MGI:MGI:1333719 PMID:10085024 defense response to Gram-positive bacterium NOT IMP MGI:MGI:2176344 2290270 MGI:MGI:1333719|PMID:10085024 MGI MGI:MGI:1333719 PMID:10085024 hydrogen peroxide catabolic process   ISO UniProtKB:P05164 2290270 MGI:MGI:2154458 MGI MGI:MGI:2154458 hydrogen peroxide catabolic process   IDA   2290270 MGI:MGI:1333719|PMID:10085024 MGI MGI:MGI:1333719 PMID:10085024 hydrogen peroxide catabolic process   IMP MGI:MGI:2176344 2290270 MGI:MGI:1333719|PMID:10085024 MGI MGI:MGI:1333719 PMID:10085024 hypochlorous acid biosynthetic process   IMP MGI:MGI:2176344 2290270 MGI:MGI:1333719|PMID:10085024 MGI MGI:MGI:1333719 PMID:10085024 low-density lipoprotein particle remodeling   ISO UniProtKB:P05164 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 negative regulation of growth of symbiont in host   IMP MGI:MGI:2176344 2290270 MGI:MGI:1333719|PMID:10085024 MGI MGI:MGI:1333719 PMID:10085024 oxidation-reduction process   ISO UniProtKB:P05164 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 oxidation-reduction process   IMP MGI:MGI:2176344 2290270 MGI:MGI:1333719|PMID:10085024 GOC MGI:MGI:1333719 PMID:10085024 oxidation-reduction process   IDA   2290270 MGI:MGI:2179579|PMID:11980719 GOC MGI:MGI:2179579 PMID:11980719 oxidation-reduction process   IDA   2290270 MGI:MGI:2157179|PMID:11792727 GOC MGI:MGI:2157179 PMID:11792727 oxidation-reduction process   IDA   2290270 MGI:MGI:3044469|PMID:15159534 GOC MGI:MGI:3044469 PMID:15159534 oxidation-reduction process   IDA   2290270 MGI:MGI:1333719|PMID:10085024 GOC MGI:MGI:1333719 PMID:10085024 removal of superoxide radicals   IMP MGI:MGI:2176344 2290270 MGI:MGI:1333719|PMID:10085024 MGI MGI:MGI:1333719 PMID:10085024 respiratory burst involved in defense response   IMP MGI:MGI:2176344 2290270 MGI:MGI:1333719|PMID:10085024 MGI MGI:MGI:1333719 PMID:10085024 response to oxidative stress   ISO NCBI:NP_001100506 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 response to yeast   IMP MGI:MGI:2176344 2290270 MGI:MGI:1333719|PMID:10085024 MGI MGI:MGI:1333719 PMID:10085024 Cellular Component Term Qualifier Evidence With Reference Notes Source Original Reference(s) extracellular space   ISO NCBI:NP_001100506 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 extracellular space   ISO UniProtKB:P05164 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 lysosome   IEA UniProtKB-KW:KW-0458 2290270 MGI:MGI:1354194 UniProtKB MGI:MGI:1354194 mitochondrion   IDA   2290270 MGI:MGI:2682130|PMID:14651853 MGI MGI:MGI:2682130 PMID:14651853 secretory granule   ISO UniProtKB:P05164 2290270 MGI:MGI:2154458 MGI MGI:MGI:2154458 Molecular Function Term Qualifier Evidence With Reference Notes Source Original Reference(s) heme binding   IEA InterPro:IPR010255|InterPro:IPR002007|InterPro:IPR019791 2290270 MGI:MGI:2152098 UniProtKB MGI:MGI:2152098 heparin binding   ISO UniProtKB:P05164 2290270 MGI:MGI:2154458 MGI MGI:MGI:2154458 metal ion binding   IEA UniProtKB-KW:KW-0479 2290270 MGI:MGI:1354194 UniProtKB MGI:MGI:1354194 oxidoreductase activity   IEA UniProtKB-KW:KW-0560 2290270 MGI:MGI:1354194 UniProtKB MGI:MGI:1354194 peroxidase activity   IDA   2290270 MGI:MGI:2179579|PMID:11980719 MGI MGI:MGI:2179579 PMID:11980719 peroxidase activity   ISO NCBI:NP_001100506 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 peroxidase activity   IDA   2290270 MGI:MGI:1333719|PMID:10085024 MGI MGI:MGI:1333719 PMID:10085024 peroxidase activity   IMP MGI:MGI:2176344 2290270 MGI:MGI:1333719|PMID:10085024 MGI MGI:MGI:1333719 PMID:10085024 peroxidase activity   IDA   2290270 MGI:MGI:3044469|PMID:15159534 MGI MGI:MGI:3044469 PMID:15159534 peroxidase activity   IDA   2290270 MGI:MGI:2157179|PMID:11792727 MGI MGI:MGI:2157179 PMID:11792727 peroxidase activity   ISO UniProtKB:P05164 2290270 MGI:MGI:2154458 MGI MGI:MGI:2154458 Molecular Pathway Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) interleukin-23 signaling pathway   ISO RGD:1346384 6484113   PID PID:200154 External Database Links KEGG Pathway Phagosome Transcriptional misregulation in cancer Pathway Interaction Database C-MYB transcription factor network (PID:200153) IL23-mediated signaling events (PID:200154) Phenotype Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) abnormal metabolism   IAGP   5509061   MGI PMID:10085024 abnormal muscle fiber morphology   IAGP   5509061   MGI PMID:15790660 abnormal neutrophil physiology   IAGP   5509061   MGI PMID:10085024 abnormal neutrophil physiology   IAGP   5509061   MGI PMID:15790660 abnormal neutrophil physiology   IAGP   5509061   MGI PMID:11181641 abnormal response to injury   IAGP   5509061   MGI PMID:15790660 atherosclerotic lesions   IAGP   5509061   MGI PMID:11181641 atherosclerotic lesions   IAGP   5509061   MGI PMID:15911707 decreased inflammatory response   IAGP   5509061   MGI PMID:16266986 increased monocyte cell number   IAGP   5509061   MGI PMID:11181641 increased physiological sensitivity to xenobiotic   IAGP   5509061   MGI PMID:16266986 increased sensitivity to induced morbidity/mortality   IAGP   5509061   MGI PMID:11181641 increased sensitivity to induced morbidity/mortality   IAGP   5509061   MGI PMID:11593004 increased susceptibility to experimental autoimmune encephalomyelitis   IAGP   5509061   MGI PMID:11108938 increased susceptibility to fungal infection   IAGP   5509061   MGI PMID:10085024 increased susceptibility to fungal infection   IAGP   5509061   MGI PMID:11181641 sepsis   IAGP   5509061   MGI PMID:11593004 Disease Annotations Acute Kidney Injury  (ISS) Acute Lung Injury  (IEP) Alzheimer Disease  (ISS) Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis  (ISS) Asthma  (ISS) Bronchiolitis, Viral  (ISS) Bronchitis, Chronic  (ISS) Burns  (ISS) Cardiovascular Diseases  (ISS) Contrast-Induced Nephropathy  (ISS) Cystic Fibrosis  (ISS) Cystitis  (ISS) Diabetes Mellitus, Experimental  (ISS) Enteritis  (ISS) Glomerulonephritis  (IPM,ISS) Hypertension, Renovascular  (ISS) Kidney Calculi  (ISS) Kidney Failure, Chronic  (ISS) Kidney Reperfusion Injury  (IPM,ISS) Lung Diseases  (ISS) Lung Diseases, Interstitial  (ISS) Lung Neoplasms  (ISS) Lupus Nephritis  (ISS) Multiple Sclerosis  (ISS) Myeloperoxidase Deficiency  (ISS) Myocardial Ischemia  (ISS) Pancreatic Neoplasms  (ISS) Pleurisy  (IEP) Pneumonia, Bacterial  (ISS) Pulmonary Disease, Chronic Obstructive  (ISS) Reperfusion Injury  (ISS) Sepsis  (IPM) Spinal Cord Injuries  (ISS) Status Asthmaticus  (ISS) Vasculitis  (ISS) Gene-Chemical Interaction Annotations (R)-camphor  (EXP) (R)-carnitine  (ISO) (S)-colchicine  (ISO) (S)-nicotine  (ISO) 1,2-phenylenediamine  (ISO) 1,7-dimethylxanthine  (EXP) 1-chloro-2,4,6-trinitrobenzene  (EXP) 1-chloro-2,4-dinitrobenzene  (ISO) 1-naphthyl isothiocyanate  (EXP,ISO) 17-HDoHE  (EXP) 2,2',4,4'-tetrachlorobiphenyl  (ISO) 2,4,6-trinitrobenzenesulfonic acid  (EXP,ISO) 2,4-dichloroaniline  (ISO) 2,4-dimethylaniline  (ISO) 2,6-dimethylaniline  (ISO) 2-amino-2-deoxy-D-glucopyranose  (ISO) 2-naphthylamine  (ISO) 3,3',5-triiodo-L-thyronine  (ISO) 3,4-dichloroaniline  (ISO) 3,4-dimethylaniline  (ISO) 3-aminobenzamide  (EXP) 4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP,ISO) 4-chloroaniline  (ISO) 4-fluoroaniline  (ISO) 4-nitroaniline  (ISO) 5-aza-2'-deoxycytidine  (ISO) 6-propyl-2-thiouracil  (ISO) 7,12-dimethyltetraphene  (EXP) acetaldehyde  (ISO) acetylsalicylic acid  (ISO) albuterol  (ISO) aldehydo-D-glucosamine  (ISO) all-trans-retinoic acid  (ISO) allopurinol  (ISO) aluminium atom  (ISO) aluminium(0)  (ISO) amifostine  (EXP) aminoglutethimide  (ISO) aminoguanidine  (ISO) amiodarone  (ISO) ammonia  (EXP) ampicillin  (ISO) aniline  (ISO) apocynin  (EXP) arachidonic acid  (EXP,ISO) arsenic atom  (ISO) arsenite(3-)  (EXP) asbestos  (ISO) benzene  (EXP,ISO) benzo[a]pyrene  (EXP) berberine  (EXP) beta-D-glucosamine  (ISO) biphenyl-4-amine  (ISO) bis(2-chloroethyl) sulfide  (EXP) bivalirudin  (ISO) bleomycin A2  (EXP,ISO) budesonide  (ISO) buta-1,3-diene  (ISO) cadmium dichloride  (EXP,ISO) camphor  (EXP) candesartan  (ISO) capsaicin  (ISO) carboplatin  (ISO) carnosine  (EXP) carrageenan  (ISO) carvedilol  (EXP,ISO) celecoxib  (ISO) ceruletide  (EXP) chlorphenamine  (ISO) chondroitin sulfate  (ISO) cis-caffeic acid  (EXP) cisplatin  (ISO) cocaine  (ISO) copper atom  (ISO) copper(0)  (ISO) crocetin  (EXP) crocidolite asbestos  (EXP,ISO) curcumin  (ISO) cyclophosphamide  (ISO) cyclosporin A  (EXP) cypermethrin  (EXP) cysteamine  (ISO) D-penicillamine  (ISO) dexamethasone  (EXP,ISO) dextran sulfate  (EXP,ISO) diarsenic trioxide  (EXP,ISO) diazoxide  (ISO) dichloroacetic acid  (EXP) dimethyl sulfoxide  (EXP) diquat  (ISO) docebenone  (EXP) domperidone  (EXP) donepezil hydrochloride  (EXP) doxorubicin  (ISO) edaravone  (ISO) emodin  (ISO) ethanol  (EXP,ISO) etoposide  (ISO) eugenol  (ISO) famotidine  (EXP,ISO) fenoterol  (ISO) ferroheme b  (ISO) fluconazole  (ISO) fulvestrant  (ISO) gadolinium trichloride  (ISO) gamma-hexachlorocyclohexane  (ISO) glutathione  (ISO) halothane  (ISO) hemin  (ISO) hyaluronic acid  (ISO) hydrogen chloride  (ISO) hydrogen peroxide  (EXP,ISO) hydroquinone  (ISO) hypochlorous acid  (ISO) indole-3-butyric acid  (ISO) indomethacin  (EXP,ISO) iron atom  (ISO) isoflurane  (ISO) isoorientin  (ISO) isoprenaline  (ISO) ketoprofen  (ISO) L-ascorbic acid  (ISO) lansoprazole  (ISO) lisinopril dihydrate  (EXP) mercury atom  (ISO) mercury(0)  (ISO) methimazole  (ISO) methotrexate  (ISO) metoclopramide  (EXP) mirtazapine  (ISO) mono(2-ethylhexyl) phthalate  (EXP) montelukast  (ISO) N,N-dimethylformamide  (ISO) N-acetyl-L-cysteine  (ISO) N-formyl-L-methionyl-L-leucyl-L-phenylalanine  (EXP,ISO) nickel sulfate  (ISO) nimesulide  (ISO) nitric oxide  (ISO) nitroglycerin  (ISO) o-toluidine  (ISO) omeprazole  (EXP,ISO) p-toluidine  (ISO) pantoprazole  (ISO) paracetamol  (EXP,ISO) paraquat  (ISO) pentobarbital  (ISO) perfluorooctanoic acid  (EXP) permethrin  (ISO) phorbol 13-acetate 12-myristate  (EXP,ISO) pirinixic acid  (EXP,ISO) piroxicam  (ISO) potassium cyanide  (ISO) prednisolone  (EXP,ISO) procainamide  (ISO) prostaglandin E2  (ISO) pyridaben  (EXP) raloxifene  (ISO) ranitidine  (ISO) resveratrol  (EXP,ISO) rolipram  (EXP,ISO) rosiglitazone  (EXP,ISO) serotonin  (ISO) sevoflurane  (ISO) sildenafil  (ISO) silicon dioxide  (EXP) silver atom  (EXP) silver(0)  (EXP) simvastatin  (EXP,ISO) sodium azide  (ISO) sodium cyanide  (ISO) streptozocin  (EXP) sulfasalazine  (ISO) tacrolimus hydrate  (ISO) taurine  (ISO) taurocholic acid  (ISO) telmisartan  (EXP) terbutaline  (ISO) tetrachloromethane  (ISO) thalidomide  (EXP) theophylline  (ISO) thiabendazole  (ISO) thioacetamide  (ISO) trans-resveratrol  (EXP,ISO) trichloroacetic acid  (EXP) trichostatin A  (ISO) troglitazone  (EXP) urethane  (EXP) ursodeoxycholic acid  (EXP) usnic acid  (ISO) valproic acid  (EXP) verapamil  (ISO) wortmannin  (ISO) zafirlukast  (ISO) zinc atom  (ISO) zinc protoporphyrin  (ISO) zinc(0)  (ISO) Gene Ontology Annotations Biological Process defense response to fungus  (IMP) defense response to Gram-positive bacterium  (IMP) hydrogen peroxide catabolic process  (IDA,IMP,ISO) hypochlorous acid biosynthetic process  (IMP) low-density lipoprotein particle remodeling  (ISO) negative regulation of growth of symbiont in host  (IMP) oxidation-reduction process  (IDA,IMP,ISO) removal of superoxide radicals  (IMP) respiratory burst involved in defense response  (IMP) response to oxidative stress  (ISO) response to yeast  (IMP) Cellular Component extracellular space  (ISO) lysosome  (IEA) mitochondrion  (IDA) secretory granule  (ISO) Molecular Function heme binding  (IEA) heparin binding  (ISO) metal ion binding  (IEA) oxidoreductase activity  (IEA) peroxidase activity  (IDA,IMP,ISO) Molecular Pathway Annotations interleukin-23 signaling pathway  (ISO) External Database Links KEGG Pathway Phagosome Transcriptional misregulation in cancer Pathway Interaction Database C-MYB transcription factor network (PID:200153) IL23-mediated signaling events (PID:200154) Phenotype Annotations abnormal metabolism  (IAGP) abnormal muscle fiber morphology  (IAGP) abnormal neutrophil physiology  (IAGP) abnormal response to injury  (IAGP) atherosclerotic lesions  (IAGP) decreased inflammatory response  (IAGP) increased monocyte cell number  (IAGP) increased physiological sensitivity to xenobiotic  (IAGP) increased sensitivity to induced morbidity/mortality  (IAGP) increased susceptibility to experimental autoimmune encephalomyelitis  (IAGP) increased susceptibility to fungal infection  (IAGP) sepsis  (IAGP) References - curated 1. Abul H, etal., Mol Cell Biochem. 2001 Jan;217(1-2):107-12. 2. Andersen GN, etal., Respir Med. 2007 Oct;101(10):2199-206. Epub 2007 Jul 20. 3. Barlak A, etal., Ren Fail. 2010;32(8):992-9. 4. Bouali H, etal., J Rheumatol. 2007 Oct;34(10):2028-34. Epub 2007 Sep 15. 5. Brovkovych V, etal., Am J Physiol Lung Cell Mol Physiol. 2008 Jul;295(1):L96-103. Epub 2008 Apr 18. 6. Cevik O, etal., Burns. 2012 Sep;38(6):861-71. doi: 10.1016/j.burns.2012.01.006. Epub 2012 Feb 20. 7. El Kebir D, etal., Am J Respir Crit Care Med. 2009 Aug 15;180(4):311-9. Epub 2009 May 29. 8. Ersahin M, etal., J Pineal Res. 2009 Aug;47(1):97-106. Epub 2009 Jun 22. 9. Ersahin M, etal., Prostaglandins Other Lipid Mediat. 2012 Sep 15. pii: S1098-8823(12)00119-0. doi: 10.1016/j.prostaglandins.2012.09.002. 10. Fiorini G, etal., Biomed Pharmacother. 2000 Jun;54(5):274-8. 11. Frode TS and Medeiros YS, Mediators Inflamm. 2001 Aug;10(4):223-7. 12. Gu J, etal., Acta Anaesthesiol Scand. 2011 Nov;55(10):1272-8. doi: 10.1111/j.1399-6576.2011.02526.x. Epub 2011 Sep 26. 13. Guilpain P, etal., Eur Respir J. 2010 Nov 11. 14. Kalayci O, etal., Turk J Pediatr. 2000 Jan-Mar;42(1):9-16. 15. Kantarci OH, etal., J Neuroimmunol 2000 Jun 26;105(2):189-94. 16. Karakoyun B, etal., Drug Chem Toxicol. 2009;32(4):312-8. 17. Kawai J, etal., Nature 2001 Feb 8;409(6821):685-90. 18. Kawashima S, etal., Nihon Jinzo Gakkai Shi. 2009;51(1):56-67. 19. Linares-Fernandez B and Alfieri AB, Invest Clin. 2009 Mar;50(1):23-33. 20. Ma N, etal., Zhonghua Nei Ke Za Zhi. 1999 Aug;38(8):523-6. 21. Matthijsen RA, etal., Am J Pathol. 2007 Dec;171(6):1743-52. Epub 2007 Nov 30. 22. Menozzi A, etal., Eur J Pharmacol. 2011 Jan 10;650(1):378-83. Epub 2010 Oct 13. 23. MGD and Homologene mouse data transfer 24. MGD data from the GO Consortium 25. MGD IEA 26. Misaka S, etal., Eur J Pharm Sci. 2009 Jun 28;37(3-4):469-76. Epub 2009 Apr 10. 27. Odobasic D, etal., J Am Soc Nephrol. 2007 Mar;18(3):760-70. Epub 2007 Jan 31. 28. Pecoits-Filho R, etal., Kidney Int Suppl. 2003 May;(84):S172-6. 29. Perianayagam MC, etal., Kidney Int. 2012 Oct;82(8):909-19. doi: 10.1038/ki.2012.235. Epub 2012 Jun 27. 30. Pipeline to import Pathway Interaction Database annotations from NCI into RGD 31. Polonikov AV, etal., J Asthma. 2009 Jun;46(5):523-8. 32. Reynolds WF, etal., Mediators Inflamm. 2006;2006(2):36735. 33. RGD automated import pipeline 34. RGD automated import pipeline for gene-chemical interactions 35. RGD Automated Pipelines 36. Sawicki M, etal., Eur J Clin Invest. 2011 Jan 12. doi: 10.1111/j.1365-2362.2010.02457.x. 37. Schabath MB, etal., Am J Epidemiol. 2005 Mar 1;161(5):412-22. 38. Sigurs N, etal., Acta Paediatr. 1994 Nov;83(11):1151-5. 39. Sommer SP, etal., J Heart Lung Transplant. 2011 Apr 4. 40. Tasdemir C, etal., Ren Fail. 2012;34(9):1144-9. doi: 10.3109/0886022X.2012.717490. Epub 2012 Sep 6. 41. Tsao KC, etal., J Clin Lab Anal. 2007;21(6):426-31. 42. Uluoglu C, etal., Gen Physiol Biophys. 2008 Mar;27(1):25-31. 43. Valenzuela DM, etal., J Neurosci 1995 Sep;15(9):6077-84. 44. Vasu VT, etal., Free Radic Res. 2011 Feb;45(2):165-76. Epub 2010 Oct 18. 45. Wang AY, etal., Am J Kidney Dis. 2010 Nov;56(5):937-46. Epub 2010 Jul 16. 46. Wheatley-Price P, etal., Cancer. 2008 Mar 1;112(5):1037-42. 47. Yamanishi Y, etal., Mod Rheumatol. 2012 Oct 21. References - uncurated PubMed 10085024   10349636   10945472   10979934   11042159   11076861   11108938   11181641   11410366   11593004   11792727   11831441   11980719   12085336   12089442   12359714   12466851   12477932   12584448   12615902   12755332   1346798   14651853   14657339   14681479   14691545   15020295   15159534   15507755   15579460   15661916   15711547   15790660   15850779   15911707   15914564   16141072   16141073   16266986   16416089   16489219   16517735   16585600   1675432   16914663   16956579   17035062   17108314   17134831   17200182   17316569   17384464   17476283   17660555   17828273   17901846   1794058   17991873   18272685   18281288   18353866   18505433   18617697   18619953   19039769   19221870   19305414   19383970   19494324   19778788   19907415   20018843   20035012   20061576   20153732   20156554   20230750   20647008   20980678   21267068   21543212   2164461   21677750   21704008   21880720   21930915   22082678   22211924   22322369   22479306   22955884   22976954   23066164   23306200   23384999   2548170   2552419   2567264   3029127   7514570   7557989   7557995   7579889   7594550   7601457   7650394   7789623   7920656   8182931   8188678   8268657   8384306   8423056   8449498   8530103   8662231   8683100   8777716   8835527   9001423   9087431   9177778   9434953   9611252   9819431   9864150 RGD Disease Portals Mpo has been annotated in the following RGD Disease Portals. Cancer Diseases Cancer Pathways Cardiovascular Diseases Cardiovascular Pathways Cardiovascular Phenotypes Diabetes Diseases Diabetes Pathways Biological Process Immune and Inflammatory Diseases Immune and Inflammatory Pathways Immune and Inflammatory Phenotypes Neurological Diseases Neurological Pathways Obesity Diseases Obesity Pathways Biological Process Respiratory Diseases Respiratory Pathways Genomics Comparative Map Data Mpo   (Mus musculus) Map Chr Position Strand Source Mouse Genome Assembly GRCm38 11 87,793,784 - 87,804,412 + NCBI Mouse cM Map 11 52.22   NCBI Mouse Celera Assembly 11 97,389,547 - 97,400,150 + NCBI Mouse Genome Assembly Build 37 11 87,607,286 - 87,617,914 + NCBI Mouse Genome Assembly Build 36.1 11 87,607,083 - 87,617,899 + NCBI Mouse Cytogenetic Map 11 C   NCBI MPO   (Homo sapiens) Map Chr Position Strand Source Human Alternate Assembly CHM1_1 17 57,362,800 - 57,373,877 - NCBI Human Genome Assembly HuRef 17 51,708,013 - 51,718,966 - NCBI Human Genome Assembly GRCh37 17 56,347,217 - 56,358,296 - NCBI Human Genome Assembly Build 36 17 53,702,216 - 53,713,295 - NCBI Human Cytogenetic Map 17 q23.1   NCBI Human Genome Assembly 17 53,702,215 - 53,713,295   NCBI Mpo   (Rattus norvegicus) Map Chr Position Strand Source Rat Cytogenetic Map 10 q26   NCBI RGSC Genome Assembly v5.0 10 75,004,128 - 75,014,496 - NCBI RGSC Genome Assembly v3.4 10 76,085,872 - 76,097,012 + NCBI Rat Celera Assembly 10 71,507,771 - 71,517,382 + NCBI Position Markers BB196773   Map Chr Position Strand Source Mouse Genome Assembly GRCm38 11 87,803,462 - 87,803,549   UniSTS Mouse Whitehead/MRC_RH 11 1137.78   UniSTS Mouse cM Map 11 49.0   UniSTS Mouse Celera Assembly 11 97,399,200 - 97,399,287   UniSTS Mouse Genome Assembly Build 37 11 87,616,964 - 87,617,051   UniSTS Mouse Cytogenetic Map 11 C   UniSTS D11Mit39   Map Chr Position Strand Source Mouse Genome Assembly GRCm38 11 87,800,372 - 87,800,540   UniSTS Mouse Whitehead_YAC 11     UniSTS Mouse Whitehead Genetic 11 44.8   UniSTS Mouse cM Map 11 49.0   UniSTS Mouse Celera Assembly 11 97,396,102 - 97,396,256   UniSTS Mouse Genome Assembly Build 37 11 87,613,874 - 87,614,042   UniSTS Mouse Cytogenetic Map 11 C   UniSTS Mpo   Map Chr Position Strand Source Mouse cM Map 11 49.0   UniSTS Mouse cM Map 11 49.0   UniSTS Mouse Celera Assembly 11 97,393,894 - 97,394,171   UniSTS Mouse Genome Assembly Build 37 11 87,611,685 - 87,611,934   UniSTS Mouse Cytogenetic Map 11 C   UniSTS X15378   Map Chr Position Strand Source Mouse Genome Assembly GRCm38 11 87,803,635 - 87,803,743   UniSTS Mouse Whitehead/MRC_RH 11 1138.16   UniSTS Mouse cM Map 11 49.0   UniSTS Mouse Celera Assembly 11 97,399,373 - 97,399,481   UniSTS Mouse Genome Assembly Build 37 11 87,617,137 - 87,617,245   UniSTS Mouse Cytogenetic Map 11 C   UniSTS RH144619   Map Chr Position Strand Source Mouse Genome Assembly GRCm38 11 87,803,481 - 87,804,410   UniSTS Mouse cM Map 11 49.0   UniSTS Mouse Celera Assembly 11 97,399,219 - 97,400,148   UniSTS Mouse Genome Assembly Build 37 11 87,616,983 - 87,617,912   UniSTS Mouse Cytogenetic Map 11 C   UniSTS Mpo   Map Chr Position Strand Source Mouse Genome Assembly GRCm38 11 87,798,183 - 87,798,432   UniSTS Mouse cM Map 11 49.0   UniSTS Mouse Celera Assembly 11 97,393,894 - 97,394,171   UniSTS Mouse Genome Assembly Build 37 11 87,611,685 - 87,611,934   UniSTS Mouse Cytogenetic Map 11 C   UniSTS Mpo   Map Chr Position Strand Source Mouse Cytogenetic Map 11 C   UniSTS Mpo   Map Chr Position Strand Source Mouse Cytogenetic Map 11 C   UniSTS QTLs in Region (Mouse Genome Assembly Build 37) The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer RGD ID Symbol Name LOD P Value Trait Sub Trait Chr Start Stop Species 4141612 Cia40_m collagen induced arthritis 40 (mouse) Not determined 11 53988346 117993212 Mouse 4142121 Tmc1m2_m Tmc1 modifier 2 (mouse) Not determined 11 56786703 114128445 Mouse 1301548 Idd4_m insulin dependent diabetes susceptibility 4 (mouse) Not determined 11 57677336 91677434 Mouse 1301182 Vmbic6_m ventral midbrain iron content 6 (mouse) Not determined 11 59777286 93777433 Mouse 4142202 Feml4_m femur length in high growth mice 4 (mouse) Not determined 11 59866991 93867100 Mouse 1301319 Dautb4_m dopamine uptake transporter binding 4 (mouse) Not determined 11 62078681 96078829 Mouse 1301956 Orch3_m autoimmune orchitis resistance 3 (mouse) Not determined 11 62736435 96736588 Mouse 1300765 Bbaa4_m B.burgdorferi-associated arthritis 4 (mouse) Not determined 11 66403911 100404032 Mouse 1301030 Bw4_m body weight QTL 4 (mouse) Not determined 11 66403911 100404032 Mouse 1300784 Prdt3_m prion disease incubation time 3 (mouse) Not determined 11 66656096 100656328 Mouse 1357766 Si5lq6_m serum IGFBP-5 level QTL 6 (mouse) Not determined 11 66656096 100656328 Mouse 1301546 Pcir2_m periosteal circumference 2 (mouse) Not determined 11 66656096 100656328 Mouse 1301833 Tbbmd5_m total body bone mineral density 5 (mouse) Not determined 11 66656096 100656328 Mouse 4141264 Qbis3_m QTL for body weight independent of sex 3 (mouse) Not determined 11 66656096 100656328 Mouse 4141767 Kwq15_m kidney weight QTL 15 (mouse) Not determined 11 66656096 100656328 Mouse 4142191 Lwq9_m liver weight QTL 9 (mouse) Not determined 11 66656096 100656328 Mouse 1300628 Lgth6_m body length 6 (mouse) Not determined 11 66656096 100656328 Mouse 1301161 Slthsr_m semilethal sex-restricted (mouse) Not determined 11 67654000 101654138 Mouse 1357580 Pltct2_m platelet count 2 (mouse) Not determined 11 69874328 103874451 Mouse 1302124 Eae7_m susceptibility to experimental allergic encephalomyelitis 7 (mouse) Not determined 11 69874328 103874451 Mouse 4141339 Nilac2_m nicotine induced locomotor activity 2 (mouse) Not determined 11 70613874 104614042 Mouse 1301681 Sle13_m systematic lupus erythematosus susceptibility 13 (mouse) Not determined 11 70613874 104614042 Mouse 1300651 Pcyts3_m plasmacytoma susceptibility 3 (mouse) Not determined 11 70613874 104614042 Mouse 1558812 Rafar_m retinoic acid induced forelimb autopod reduction (mouse) Not determined 11 70613874 104614042 Mouse 1300957 Pbd1_m peak bone density 1 (mouse) Not determined 11 71990137 105990222 Mouse 1301404 Sbmd4_m spinal bone mineral density 4 (mouse) Not determined 11 71990137 105990222 Mouse 1301654 Aliq1_m acute lung injury QTL 1 (mouse) Not determined 11 72696613 106696777 Mouse 1301310 Tmevd5_m Theiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse) Not determined 11 72696613 106696777 Mouse 1558996 Bomd7_m bone mineral density 7 (mouse) Not determined 11 72696613 106696777 Mouse 4142348 Pstc2_m periosteal circumference 2 (mouse) Not determined 11 72789103 106789221 Mouse 1357551 Stzid_m streptozotocin induced diabetes susceptibility (mouse) Not determined 11 73114273 107114396 Mouse 1301414 Heal10_m wound healing/regeneration 10 (mouse) Not determined 11 77407671 111407810 Mouse 4141332 Azdm5_m Alzheimer's disease modifier 5 (mouse) Not determined 11 77407671 111407810 Mouse 1301535 Pas5b_m pulmonary adenoma susceptibility 5b (mouse) Not determined 11 79146953 113147090 Mouse 1301038 C10bw3_m castaneus 10 week body weight 3 (mouse) Not determined 11 79868181 113868314 Mouse 1301153 Estq3_m estradiol regulated response QTL 3 (mouse) Not determined 11 79868181 113868314 Mouse 4142145 Wg7_m weight gain in high growth mice 7 (mouse) Not determined 11 79868181 113868314 Mouse 4142072 Brwq1_m brain weight QTL 1 (mouse) Not determined 11 79868181 113868314 Mouse 1300766 Skull16_m skull morphology 16 (mouse) Not determined 11 81544969 115545124 Mouse 1301313 Pas5a_m pulmonary adenoma susceptibility 5a (mouse) Not determined 11 81544969 115545124 Mouse 1558999 Ethm4_m ethanol induced thermoregulation 4 (mouse) Not determined 11 81544969 115545124 Mouse 1300649 Crhq1_m compensatory renal hypertrophy QTL 1 (mouse) Not determined 11 81544969 115545124 Mouse 4141508 Tailq8_m tail length QTL 8 (mouse) Not determined 11 82348186 116348308 Mouse 1301072 Eae22_m experimental allergic encephalomyelitis 22 (mouse) Not determined 11 82348186 116348308 Mouse Sequence Nucleotide Sequences Nucleotide RefSeqs NM_010824 (Get FASTA) Search GEO for Microarray Profiles GenBank Nucleotide AAHY01094975 (Get FASTA) Search GEO for Microarray Profiles   AK160229 (Get FASTA) Search GEO for Microarray Profiles   AK220229 (Get FASTA) Search GEO for Microarray Profiles   AL604022 (Get FASTA) Search GEO for Microarray Profiles   AY494708 (Get FASTA) Search GEO for Microarray Profiles   AY500847 (Get FASTA) Search GEO for Microarray Profiles   BC053912 (Get FASTA) Search GEO for Microarray Profiles   BY352425 (Get FASTA) Search GEO for Microarray Profiles   CA547566 (Get FASTA) Search GEO for Microarray Profiles   CH466556 (Get FASTA) Search GEO for Microarray Profiles   CN661559 (Get FASTA) Search GEO for Microarray Profiles   CU393486 (Get FASTA) Search GEO for Microarray Profiles   X15313 (Get FASTA) Search GEO for Microarray Profiles   X15378 (Get FASTA) Search GEO for Microarray Profiles Reference Sequences RefSeq Acc Id: NM_010824 RefSeq Status: VALIDATED Type: CODING Protein Acc Id: NP_034954 Peptide Label: precursor Position: Map Chr Position Strand Source Mouse Genome Assembly GRCm38 11 87,793,784 - 87,804,412 + ENTREZGENE Mouse cM Map 11   + ENTREZGENE Mouse Celera Assembly 11 97,389,547 - 97,400,150 + RGD Mouse Genome Assembly Build 37 11 87,607,286 - 87,617,914 + RGD Protein Sequences Protein RefSeqs NP_034954 (Get FASTA) GenBank Protein AAH53912 (Get FASTA)   AAR87486 (Get FASTA)   AAR99349 (Get FASTA)   BAD90154 (Get FASTA)   CAA33373 (Get FASTA)   CAA33439 (Get FASTA)   EDL15833 (Get FASTA)   P11247 (Get FASTA) Promoters RGD ID: 6885816 Promoter ID: EPDNEW_M6359 Type: preliminary Name: Mpo_1 Description: myeloperoxidase SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) Position: Map Chr Position Strand Source Mouse Genome Assembly Build 36.1 11 87,607,270 - 87,607,330   EPDNEW Additional Information External Database Links Database Acc Id Source(s) Ensembl Genes ENSMUSG00000009350 ENTREZGENE Ensembl Protein ENSMUSP00000020779 ENTREZGENE Ensembl Transcript ENSMUST00000020779 ENTREZGENE Entrez Gene 17523 ENTREZGENE Gene3D-CATH Haem_peroxidase_animal UniProtKB/Swiss-Prot Germonline ENSMUSG00000009350 HomoloGene Group ID 55450 ENTREZGENE InterPro Haem_peroxidase UniProtKB/Swiss-Prot   Haem_peroxidase_animal UniProtKB/Swiss-Prot   Haem_peroxidase_animal_subgr UniProtKB/Swiss-Prot IPI IPI00113480 UniProtKB/Swiss-Prot   IPI00648886 UniProtKB/TrEMBL   IPI00929801 UniProtKB/TrEMBL   IPI00974625 UniProtKB/TrEMBL   IPI01016228 UniProtKB/TrEMBL KEGG Report mmu:17523 ENTREZGENE, UniProtKB/Swiss-Prot MGD MGI:97137 ENTREZGENE Pfam An_peroxidase UniProtKB/Swiss-Prot PharmGKB MPO RGD PRINTS ANPEROXIDASE UniProtKB/Swiss-Prot PROSITE PEROXIDASE_1 UniProtKB/Swiss-Prot   PEROXIDASE_2; FALSE_NEG UniProtKB/Swiss-Prot   PEROXIDASE_3 UniProtKB/Swiss-Prot Superfamily-SCOP Peroxidase_super UniProtKB/Swiss-Prot UniGene Mm.4668 ENTREZGENE UniProt E9PUN4_MOUSE UniProtKB/TrEMBL   F7DC05_MOUSE UniProtKB/TrEMBL   F8WGZ9_MOUSE UniProtKB/TrEMBL   PERM_MOUSE UniProtKB/Swiss-Prot   Q571G0_MOUSE UniProtKB/TrEMBL   Q6RFG4_MOUSE UniProtKB/TrEMBL   Q7TMS4_MOUSE UniProtKB/TrEMBL

More on Mpo Entrez Gene Ensembl Gene Genome Browser MGI Report NCBI Map Viewer Vista Vista + UCSC RGD Object Information RGD ID: 10916 Created: 2000-05-25 Species: Mus musculus Last Modified: 2013-05-14 Status: ACTIVE