Gene: Ercc2 (excision repair cross-complementing rodent repair deficiency, complementation group 2)  Mus musculus

Symbol: Ercc2
Name: excision repair cross-complementing rodent repair deficiency, complementation group 2
Description: ENCODES a protein that exhibits 5'-3' DNA helicase activity (ortholog); DNA-dependent ATPase activity (ortholog); protein C-terminus binding (ortholog); INVOLVED IN aging; apoptotic process; bone mineralization; PARTICIPATES IN nucleotide excision repair pathway; ASSOCIATED WITH abnormal adipose tissue distribution; abnormal cell death; abnormal cell physiology; ASSOCIATED WITH Alzheimer Disease (ortholog); Asphyxia (ortholog); Cerebrooculofacioskeletal Syndrome 2 (ortholog); FOUND IN nucleus; cyclin-dependent protein kinase activating kinase holoenzyme complex (ortholog); cytoplasm (ortholog); INTERACTS WITH benzo[a]pyrene; clofibrate; imiquimod
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: AA407812; AU020867; AW240756; CXPD; CXPD; DNA excision repair protein ERCC-2; DNA repair protein complementing XP-D cells; Ercc-2; OTTMUSP00000026882; OTTMUSP00000026883; OTTMUSP00000026884; OTTMUSP00000026885; TFIIH basal transcription factor complex helicase subunit; TFIIH basal transcription factor complex helicase XPD subunit; xeroderma pigmentosum group D-complementing protein; XPD
Orthologs: Homo sapiens : ERCC2 (excision repair cross-complementing rodent repair deficiency, complementation group 2)  HGNC
Rattus norvegicus : Ercc2 (excision repair cross-complementing rodent repair deficiency, complementation group 2)
Latest Assembly: Mouse Genome Assembly Build 37
Position:
MapChrPositionStrandSource
Mouse Genome Assembly GRCm38719,382,039 - 19,395,692+NCBI
Mouse cM Map79.62 NCBI
Mouse Celera Assembly716,788,799 - 16,802,456+NCBI
Mouse Genome Assembly Build 37719,967,388 - 19,981,041+NCBI
Mouse Genome Assembly Build 36.1719,967,388 - 19,981,041+NCBI
Mouse Cytogenetic Map7 A3 NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Mouse Genome Assembly Build 37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ercc2
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RGD Object Information
RGD ID: 1319265
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2013-04-02
Status: ACTIVE