Biological Process
| aging | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:2179786|PMID:11950998 | MGI | MGI:MGI:2179786 PMID:11950998 |
| aging | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:3798119|PMID:18545656 | MGI | MGI:MGI:3798119 PMID:18545656 |
| aging | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:3692802|PMID:17020410 | MGI | MGI:MGI:3692802 PMID:17020410 |
| apoptotic process | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:3798119|PMID:18545656 | MGI | MGI:MGI:3798119 PMID:18545656 |
| bone mineralization | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:3692802|PMID:17020410 | MGI | MGI:MGI:3692802 PMID:17020410 |
| cell cycle checkpoint | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| cell proliferation | | IMP | MGI:MGI:2183947 | 2290270 | MGI:MGI:3715429|PMID:17554309 | MGI | MGI:MGI:3715429 PMID:17554309 |
| central nervous system myelin formation | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:3771455|PMID:17952069 | MGI | MGI:MGI:3771455 PMID:17952069 |
| chromosome segregation | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| DNA repair | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:2179786|PMID:11950998 | MGI | MGI:MGI:2179786 PMID:11950998 |
| embryonic cleavage | | IMP | MGI:MGI:2183947 | 2290270 | MGI:MGI:1101629|PMID:9426063 | MGI | MGI:MGI:1101629 PMID:9426063 |
| erythrocyte maturation | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:3692802|PMID:17020410 | MGI | MGI:MGI:3692802 PMID:17020410 |
| extracellular matrix organization | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:1267106|PMID:9651581 | MGI | MGI:MGI:1267106 PMID:9651581 |
| hair cell differentiation | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:3692802|PMID:17020410 | MGI | MGI:MGI:3692802 PMID:17020410 |
| hair cell differentiation | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| hair cycle process | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:3692802|PMID:17020410 | MGI | MGI:MGI:3692802 PMID:17020410 |
| hair follicle maturation | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:1267106|PMID:9651581 | MGI | MGI:MGI:1267106 PMID:9651581 |
| hematopoietic stem cell differentiation | | IMP | MGI:MGI:2183947 | 2290270 | MGI:MGI:3715429|PMID:17554309 | MGI | MGI:MGI:3715429 PMID:17554309 |
| in utero embryonic development | | IMP | MGI:MGI:3696121|MGI:MGI:3693615 | 2290270 | MGI:MGI:3692802|PMID:17020410 | MGI | MGI:MGI:3692802 PMID:17020410 |
| induction of apoptosis | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| multicellular organism growth | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:3692802|PMID:17020410 | MGI | MGI:MGI:3692802 PMID:17020410 |
| negative regulation of apoptotic process | | IMP | MGI:MGI:2183947 | 2290270 | MGI:MGI:3715429|PMID:17554309 | MGI | MGI:MGI:3715429 PMID:17554309 |
| nucleobase-containing compound metabolic process | | IEA | InterPro:IPR006555 | 2290270 | MGI:MGI:2152098 | UniProtKB | MGI:MGI:2152098 |
| nucleotide-excision repair | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:2179786|PMID:11950998 | MGI | MGI:MGI:2179786 PMID:11950998 |
| nucleotide-excision repair | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:1267106|PMID:9651581 | MGI | MGI:MGI:1267106 PMID:9651581 |
| nucleotide-excision repair | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:2154458 | MGI | MGI:MGI:2154458 |
| nucleotide-excision repair, DNA incision | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| positive regulation of DNA binding | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:3771455|PMID:17952069 | MGI | MGI:MGI:3771455 PMID:17952069 |
| positive regulation of transcription from RNA polymerase II promoter | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| positive regulation of transcription, DNA-dependent | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| post-embryonic development | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:2179786|PMID:11950998 | MGI | MGI:MGI:2179786 PMID:11950998 |
| post-embryonic development | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:3692802|PMID:17020410 | MGI | MGI:MGI:3692802 PMID:17020410 |
| protein phosphorylation | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| regulation of transcription, DNA-dependent | | IEA | UniProtKB-KW:KW-0805 | 2290270 | MGI:MGI:1354194 | UniProtKB | MGI:MGI:1354194 |
| response to DNA damage stimulus | | IEA | UniProtKB-KW:KW-0227 | 2290270 | MGI:MGI:1354194 | UniProtKB | MGI:MGI:1354194 |
| response to oxidative stress | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:2179786|PMID:11950998 | MGI | MGI:MGI:2179786 PMID:11950998 |
| response to oxidative stress | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| response to UV | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:3692802|PMID:17020410 | MGI | MGI:MGI:3692802 PMID:17020410 |
| skin development | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:1267106|PMID:9651581 | MGI | MGI:MGI:1267106 PMID:9651581 |
| skin development | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:3692802|PMID:17020410 | MGI | MGI:MGI:3692802 PMID:17020410 |
| spinal cord development | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:3692802|PMID:17020410 | MGI | MGI:MGI:3692802 PMID:17020410 |
| transcription from RNA polymerase II promoter | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| transcription, DNA-dependent | | IEA | UniProtKB-KW:KW-0804 | 2290270 | MGI:MGI:1354194 | UniProtKB | MGI:MGI:1354194 |
| transcription-coupled nucleotide-excision repair | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| UV protection | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:2154458 | MGI | MGI:MGI:2154458 |
| UV protection | | IMP | MGI:MGI:2183949 | 2290270 | MGI:MGI:1267106|PMID:9651581 | MGI | MGI:MGI:1267106 PMID:9651581 |
Cellular Component
| cyclin-dependent protein kinase activating kinase holoenzyme complex | colocalizes_with | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| cytoplasm | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| cytoskeleton | | IEA | UniProtKB-KW:KW-0206 | 2290270 | MGI:MGI:1354194 | UniProtKB | MGI:MGI:1354194 |
| holo TFIIH complex | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| MMXD complex | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| nucleus | | IDA | | 2290270 | MGI:MGI:3771455|PMID:17952069 | MGI | MGI:MGI:3771455 PMID:17952069 |
| nucleus | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| spindle | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
Molecular Function
| 4 iron, 4 sulfur cluster binding | | IEA | UniProtKB-KW:KW-0004 | 2290270 | MGI:MGI:1354194 | UniProtKB | MGI:MGI:1354194 |
| 5'-3' DNA helicase activity | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| ATP binding | | IEA | InterPro:IPR006555|InterPro:IPR010614|InterPro:IPR002464|InterPro:IPR001945 | 2290270 | MGI:MGI:2152098 | UniProtKB | MGI:MGI:2152098 |
| ATP binding | | IEA | UniProtKB-KW:KW-0067 | 2290270 | MGI:MGI:1354194 | UniProtKB | MGI:MGI:1354194 |
| ATP-dependent DNA helicase activity | | IEA | InterPro:IPR010614|InterPro:IPR006554|InterPro:IPR001945 | 2290270 | MGI:MGI:2152098 | UniProtKB | MGI:MGI:2152098 |
| ATP-dependent helicase activity | | IEA | InterPro:IPR006555|InterPro:IPR002464 | 2290270 | MGI:MGI:2152098 | UniProtKB | MGI:MGI:2152098 |
| DNA binding | | IEA | InterPro:IPR010614|InterPro:IPR001945 | 2290270 | MGI:MGI:2152098 | UniProtKB | MGI:MGI:2152098 |
| DNA binding | | IEA | UniProtKB-KW:KW-0238 | 2290270 | MGI:MGI:1354194 | UniProtKB | MGI:MGI:1354194 |
| DNA-dependent ATPase activity | contributes_to | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| helicase activity | | IEA | UniProtKB-KW:KW-0347 | 2290270 | MGI:MGI:1354194 | UniProtKB | MGI:MGI:1354194 |
| hydrolase activity | | IEA | UniProtKB-KW:KW-0378 | 2290270 | MGI:MGI:1354194 | UniProtKB | MGI:MGI:1354194 |
| hydrolase activity, acting on acid anhydrides | | IEA | InterPro:IPR014013 | 2290270 | MGI:MGI:2152098 | UniProtKB | MGI:MGI:2152098 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | | IEA | InterPro:IPR006555|InterPro:IPR006554|InterPro:IPR001945 | 2290270 | MGI:MGI:2152098 | UniProtKB | MGI:MGI:2152098 |
| iron-sulfur cluster binding | | IEA | UniProtKB-KW:KW-0411 | 2290270 | MGI:MGI:1354194 | UniProtKB | MGI:MGI:1354194 |
| metal ion binding | | IEA | UniProtKB-KW:KW-0479 | 2290270 | MGI:MGI:1354194 | UniProtKB | MGI:MGI:1354194 |
| nucleic acid binding | | IEA | InterPro:IPR006555|InterPro:IPR002464 | 2290270 | MGI:MGI:2152098 | UniProtKB | MGI:MGI:2152098 |
| nucleotide binding | | IEA | UniProtKB-KW:KW-0547 | 2290270 | MGI:MGI:1354194 | UniProtKB | MGI:MGI:1354194 |
| protein C-terminus binding | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| protein kinase activity | contributes_to | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| protein N-terminus binding | | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| RNA polymerase II carboxy-terminal domain kinase activity | contributes_to | ISO | UniProtKB:P18074 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 |
| 1301377 | Mprf_m | maternal performance (mouse) | | | Not determined | | 7 | 1 | 20266694 | Mouse |
| 1357660 | Manln7_m | mandible length 7 (mouse) | | | Not determined | | 7 | 1 | 20266694 | Mouse |
| 1301695 | Manz5_m | mandible size 5 (mouse) | | | Not determined | | 7 | 1 | 20266694 | Mouse |
| 1301177 | Vent3_m | ventricular size 3 (mouse) | | | Not determined | | 7 | 1 | 20464077 | Mouse |
| 1302188 | Lxw6_m | lupus BXSB x NZW 6 (mouse) | | | Not determined | | 7 | 1 | 21646749 | Mouse |
| 1558795 | Avptaq1_m | Avp transcript abundance QTL 1 (mouse) | | | Not determined | | 7 | 1 | 21955565 | Mouse |
| 1558887 | Crhr1taq1_m | Crhr1 transcript abundance QTL 1 (mouse) | | | Not determined | | 7 | 1 | 21955565 | Mouse |
| 1300693 | Mmtg3_m | modifier of mammary tumor growth 3 (mouse) | | | Not determined | | 7 | 2580218 | 36580441 | Mouse |
| 1301572 | Sluc30_m | susceptibility to lung cancer 30 (mouse) | | | Not determined | | 7 | 3283120 | 37283268 | Mouse |
| 4142339 | Spmd3_m | spermatogenesis defect 3 (mouse) | | | Not determined | | 7 | 10257545 | 44257688 | Mouse |
| 1300758 | Bomd4_m | bone mineral density 4 (mouse) | | | Not determined | | 7 | 10523163 | 44523313 | Mouse |
| 1558951 | mdlk1_m | modifier of Dlk1 (mouse) | | | Not determined | | 7 | 11074461 | 45074578 | Mouse |
| 1357699 | Nhdlq6_m | non-HDL QTL 6 (mouse) | | | Not determined | | 7 | 11074461 | 45074578 | Mouse |
| 1558893 | Spir1_m | Streptococcus pneumoniae infection resistance 1 (mouse) | | | Not determined | | 7 | 11391392 | 45391530 | Mouse |
| 1301627 | Vmbic4_m | ventral midbrain iron content 4 (mouse) | | | Not determined | | 7 | 14118079 | 48118215 | Mouse |
| 1301041 | Prnr2_m | prion resistance 2 (mouse) | | | Not determined | | 7 | 14118079 | 48118215 | Mouse |
| 1558790 | Mmtp1_m | modifier of mammary tumor progression 1 (mouse) | | | Not determined | | 7 | 14118079 | 48118215 | Mouse |
| 4141790 | Hfem1_m | Hfe modifier 1 (mouse) | | | Not determined | | 7 | 14118079 | 48118215 | Mouse |
| 1301352 | Bis4_m | beta-carboline induced seizures 4 (mouse) | | | Not determined | | 7 | 17527929 | 51528044 | Mouse |